LOCUS       c00311_gnlPro..        10698 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DBJELEOO_311.
ACCESSION   c00311_gnlPro..
VERSION     c00311_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:17:50
            Original ID  :: gnl|Prokka|DBJELEOO_311
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10698
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10698
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5449:10698]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5450..10698
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10698
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10698
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..194)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg311_1"
                     /sec_met_domain="HMGL-like (E-value: 1.2e-16, bitscore:
                     50.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTTLRDGEQTSGVSFAAHEKLSIAQALLDLGVNRLEIASARVSD
                     GEFEAVKRLASWAGRTGNI"
     CDS             complement(255..842)
                     /locus_tag="ctg311_2"
                     /transl_table=11
                     /translation="MKQKFNIITSTCVPLPLENVDTDQIIPARFLKATDKKGFGENLFR
                     DWRYDKQGNKIESFVLNDPTYGGQILVAGKNFGSGSSREHAAWAIADYGFRVVVSSFFA
                     DIHKNNELNNFVLPVVVSEPFLAELFDSIFADPKTEVEVNLPAQTITNKATGKSEHFDI
                     NAYKKDCFVNGLDDIDYLLSNKEKIEAFERRR"
     CDS             complement(870..2264)
                     /locus_tag="ctg311_3"
                     /transl_table=11
                     /translation="MNTLFDKIWDSHVVTMIEEGPTQLYIDRLYCHEVTSPQAFASMRR
                     RGLKPFRPERIYCMPDHNTPTHDQDKPIEDPVSKNQVDTLAKNAAEFGLTHYGMMDERN
                     GIIHVVGPERGLTLPGMTIVCGDSHTSTHGAVGAVAFGIGTSEVEMVMASQCILQAKPK
                     TMRICVEGNLGKGVTAKDVALYIMSKVTTSGATGYFIEYAGAAIRSLTMEGRLTLCNLS
                     IEMGARGGMIAPDETTFAYLKGRENAPAGEEWDKAVAYWKTLKSGDDAVFDKEILFDAA
                     DIEPMVTYGTNPGMGMGVTEHIPTVEGMNDVEKASFMKSMEYMGFEPGESLLGKKIDYV
                     FLGSCTNGRIEDFRAFASIAKGRKKADHVVAWLVPGSWLVDAQIREEGLDKIFEEAGFR
                     LRQPGCSACLAMNDDKIPAGKYAVSTSNRNFEGRQGPGARTILAGPLVAAAAAVTGEIT
                     DPRTFF"
     CDS             complement(2275..3771)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg311_4"
                     /sec_met_domain="HMGL-like (E-value: 8.8e-94, bitscore:
                     303.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRLFIFDTTLRDGEQVPGCQLNSIEKIQVAKALEELGVDVIEA
                     GFPVSSPGDFNSVVEISKAVTWPTICALTRAVEKDIDVAAEALKYAKHGRIHTGIGTSD
                     YHIRYKFNSNQEDILERAVAAAKYAKRYVEDVEFYCEDAGRTDNEYLARVVEAVIKAGA
                     TVVNIPDTTGYCLPDEYGAKIKYLMDHVDGIENAIISTHCHNDLGMATANTVQGVLNGA
                     RQVEVTMNGIGERAGNTSLEEIAMIFKSHKERGIITNINTTKIYGVSRMVSSLMNMPIQ
                     PNKAIVGRNAFAHSSGIHQDGVLKNRESYEIIDPKDVGIDDNAIVLTARSGRAALKHRL
                     QVLGVELSQEKLDKVYEEFLKLADRKKDINDDDILMLAGKDRTAMHRIKLEYLQVTSGV
                     GLQSVASICLNIAGERFEAAASGNGPVDAAIKAVKSIIHRTMTIQEFLIQAINKGSDDM
                     GKVHMQVEYEGNRYYGFAANTDIIAASVEAFIDAINKFVK"
     CDS             complement(4119..5306)
                     /locus_tag="ctg311_5"
                     /transl_table=11
                     /translation="LLKYYIMKKFQILVMLLWLSVCLAGAVESKIRLVHGPYLQNLGPD
                     EVTIVWLSDKPSVGWVELAPDDDTNFYATERPKYYDARNGVKNTSTIHTVKIKGLKPGT
                     NYRYRVFVQEVLSHVGHKIIYGNYASTDVYSKKPLVFKTSDPADNSVSFAMVNDIHGKN
                     DLLTNLVSKCDLKKTDFFLFNGDMVSVFNEENHIFDGFMDTATKLFASEIPMYYTRGNH
                     ETRGAFATEFQRYFSAKEENIYYTFRQGPICFVILDTGEDKPDSDIEYAGITVYDEYRT
                     EQAEWLRRVLDSKEYKDAPFKIIVAHIPPIGGWHGNLEVEQKFMPLLRDAKPDVMLCGH
                     LHRFIHQDATDRTPFPIIVNSNTAILKAAADPKELKIQVVDVDGKVVDQFSIKKP"
     CDS             complement(5450..6493)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg311_6"
                     /sec_met_domain="IlvN (E-value: 5.5e-45, bitscore: 142.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.8e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDEVIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRPGKTYDKAVADGWVPGETLFGIEEACERATIIQVLLSDAAQIE
                     CWPRIKKYLTPGKALYFSHGFAITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQGR
                     GLNSSYAIFQDATGRAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQGL
                     LLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWMG
                     PFHDAVKPVFEKLYREVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVVR
                     KLRPENN"
     CDS             complement(6579..7349)
                     /locus_tag="ctg311_7"
                     /transl_table=11
                     /translation="VVCELPQQKRTMDKDKSKIGEFHFVTEPYLLDFRGRVTIPMIGNY
                     LIHVASSHAAERGFGFNDMSERHTAWVLSRLAIEMIEYPAMSEPITLYTWVDEVGRLFT
                     SRCFELVDGNGKTFGYARSIWAAIDVETRRPTLLDIARLSAYVTDRPCPIEKPGKIAAV
                     ENETEGVPYFIKYSDLDINGHLNSIKYMEHLLDLFDLDLFKTKDIKRFEIAYQSEGKYG
                     MKLMLYKREADNGKYDMAICNEGKAICRAAVMWH"
     CDS             complement(7292..7909)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg311_8"
                     /sec_met_domain="ALS_ss_C (E-value: 7.5e-18, bitscore:
                     54.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENTVGLLNQITIIFTRRQLNIETLSVSPSAIQ
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVFQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNETCVVLEKSGHYDETQALFRELSETIGVLQFIRSGRVAITKS
                     RVERLSDMLAEMERKLQEKKITYGWFANCPNRKEPWIKIKAK"
     CDS             complement(7922..9622)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg311_9"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-51, bitscore:
                     163.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKSLIAEGVDTIFGYPGGQAIPIYDSLYDYRDK
                     LKHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGFVDYEYKKVDYIRSYQPEPDINQDRIKAAAALINKAEKPFCLVGQGVLLGG
                     AEEELKAFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKVIHLDIDNSEIGKNVSVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDAQEEYEKVIEKELYPMNGSLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKRTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLDVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAVRTVE
                     KREELDEAIAEMLNHNGAFVLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(9646..10698)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg311_10"
                     /sec_met_domain="ILVD_EDD (E-value: 2.9e-122, bitscore:
                     398.2, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="FLNAMSLDIAMGGSTNTVLHLLAIAQEAEAGFTMDDIDMLSRKTP
                     CLCKVAPNTHTYHVQDVNRAGGIMGIMNELLKNGLVDGNVKRVDGMTLAEAVDKFAITS
                     PNVTDEAVKKYKSAPAHRFSIRMGSQETYYKELDTDRAAGCIRDIEHAYSKDGGLAVLK
                     GNIALDGCVVKTAGVDESIWKFAGPAKVFDSQDAACEGILGGKVVSGDVVVITHEGPKG
                     GPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGTSGLSIGHISPEAAAGGAIGLVKDG
                     DIIEIDIPERTINVKVSDEELAERRKAEEARGTKAFTPPHRQRVVSKALRAYGKMVSSA
                     DKGGVRVVED"
ORIGIN
        1 tggatgtttc cggtacgccc cgcccaggaa gccagacgct tcacggcctc aaactcaccg
       61 tccgagacac gtgcagatgc gatctccaga cggttcacac ccagatcaag caatgcctgt
      121 gcaatgctca acttctcatg cgccgcaaaa gaaactcccg atgtctgttc cccgtcacgc
      181 agggtggtat ccattatttc tatcataatt gttcatatat aacgctactt ttagcttgat
      241 ccaaaagcaa caaactaacg tctcctttca aatgcttcaa tcttttcctt attggaaagc
      301 agataatcga tgtcatcgag gccattcaca aagcagtctt ttttgtaggc gttgatatcg
      361 aagtgctcgc tcttacccgt agccttattg gtgatggttt gggcaggcag gttgacttcg
      421 acttctgttt tcggatcggc aaaaatcgag tcgaaaagct cggccagaaa aggttcgcta
      481 accaccacag ggagaacaaa gttattcagt tcattgtttt tgtggatatc cgcaaaaaaa
      541 ctggacacaa ctacacgaaa cccataatcg gcaatcgccc aagcagcatg ttcgcgactg
      601 gaacccgagc cgaagttttt ccccgccacc agtatctgtc cgccgtaggt cggatcattc
      661 aagacaaacg attctatttt atttccctgc ttgtcgtacc gccagtcgcg gaacaaattt
      721 tcaccaaacc cttttttgtc ggttgctttc aggaaacgag caggaatgat ctggtccgta
      781 tccacattct ctaaaggaag ggggacgcag gttgatgtaa tgatattgaa tttctgtttc
      841 atgaatgtta aaatttatga tttatgattt cagaaaaacg ttctcggatc ggtaatttcc
      901 ccagtcacgg ctgccgcagc agctactagc ggtccagcca gaatcgtacg ggcccccggc
      961 ccctgacgtc cttcaaagtt acggttgctt gtcgaaactg catattttcc tgccgggatc
     1021 ttatcgtcgt tcattgccag acaagccgag catcccggtt gacgtaaccg gaaaccggct
     1081 tcttcgaata tcttgtctaa cccttcttca cggatctgcg catctaccag ccaggagcca
     1141 ggaaccagcc aggcgaccac atggtcggct ttcttccgtc ccttagcaat ggaagcaaaa
     1201 gcacgaaagt cctcgatacg gccattggta caagagccta agaacacata gtcgatcttc
     1261 ttgcccaaca aggattcacc cggttcgaac cccatatact ccatcgattt cataaaagaa
     1321 gctttctcca catcgttcat accctcgaca gtcgggatat gttcggtaac tcccattccc
     1381 atacccggat tggtaccata cgtcaccatc ggttcgatat cggcagcatc aaacagaatc
     1441 tctttgtcaa acacagcatc atcgccactt ttcaaagtct tccaataagc aaccgcctta
     1501 tcccattctt cgccggcagg agcattttca cgtcccttaa gataagcgaa tgtcgtttcg
     1561 tcaggagcga tcataccacc acgcgctccc atttcaatag acaggttgca caaagtcaaa
     1621 cgcccctcca tcgtcaagct acggatcgcc gcaccagcat actcgatgaa atatccggtt
     1681 gcaccgctgg tcgtcacttt cgacatgata taaagggcga catcctttgc tgtcacccct
     1741 ttccctagat taccttccac acagatacgc atggttttcg gctttgcctg caaaatgcac
     1801 tgggaagcca taaccatttc cacttcactg gttccgatac cgaaagcgac cgcaccgact
     1861 gctccatgag tagaagtatg cgaatcaccg caaacgatcg tcatccccgg caaggtcagt
     1921 ccacgttccg ggcctaccac atgaataata ccattcctct catccatcat tccataatga
     1981 gtcaaaccaa attcggcagc attctttgcc agcgtatcga cttgattctt cgaaacagga
     2041 tcttcgatcg gtttatcctg atcgtgtgtc ggcgtgttat gatccggcat acaatagata
     2101 cgttccggac gaaacggctt caaaccacgt cgacgcatac tggcaaaagc ctgtggacta
     2161 gttacttcat gacagtacaa cctgtcaatg taaagttgtg tgggcccctc ttcgatcatc
     2221 gtcactacgt gggaatccca aatcttgtca aataatgtat tcataattat caattcactt
     2281 cacaaattta ttaattgcat cgataaatgc ctctacagaa gcggctataa tatcggtatt
     2341 ggcagcaaaa ccataataac ggttcccttc gtactcaacc tgcatatgta ctttccccat
     2401 atcgtcactg cctttattaa tcgcttgaat caaaaactcc tgaatcgtca tcgtacggtg
     2461 aataatagat ttcaccgcct tgatagcagc atcaacagga ccgttgccag aagcggcggc
     2521 ctcaaacctc tcaccagcta tattcaggca aatgctggcc acagactgca aaccgacacc
     2581 ggaggtcacc tgtaaatatt ccaacttgat acgatgcatg gccgtgcggt ctttgccagc
     2641 aagcatcaag atatcgtcgt cgttgatatc tttcttacgg tcagccagtt tcaagaattc
     2701 ttcataaacc ttatctagtt tttcctgaga caattcgacg cccaatacct gtaaacggtg
     2761 tttcaatgcc gcacgtccgc tacgggcagt cagcacgatt gcattatcgt cgattcctac
     2821 atctttcgga tcgatgattt cataactttc acgattcttc aaaacgccat cctgatggat
     2881 gccggaagaa tgagcgaacg cgttacgtcc gacgatcgcc ttattcggct ggataggcat
     2941 gttcatcagg ctagacacca tacggctgac tccgtaaatc tttgtcgtat tgatattggt
     3001 aataatgcca cgttctttgt gactcttgaa aatcattgcg atttcttcca aggatgtatt
     3061 accggcacgt tcacctatac cgttcatggt gacttccacc tgacgtgcac cattcaagac
     3121 accctgcaca gtattggcgg tagccatccc caaatcatta tgacagtggg tagaaatgat
     3181 agcattctcg ataccgtcta catgatccat cagatatttg attttcgccc catattcgtc
     3241 cggcaggcaa taaccggtcg tatcagggat attgacaact gtcgcgccag ctttgatgac
     3301 cgcttctacc acacgtgcca gatattcgtt gtcagtacgt ccggcatctt cgcaataaaa
     3361 ttcgacgtct tccacatatc tcttggcata tttggcagca gcgacagccc gttccaaaat
     3421 atcttcctga ttcgaattga acttatacct gatatgataa tcggacgttc caatacctgt
     3481 atgaatacgt ccgtgctttg catatttcag tgcttcggca gccacatcaa tatctttttc
     3541 taccgcacgg gtaagcgcac agattgtagg ccacgttacg gctttcgata tttcaacaac
     3601 gctattgaaa tctcccggac tcgatacggg gaaaccggct tctatcacgt ctactcccag
     3661 ttcttccaga gctttggcta cctgaatctt ttcaatacta tttaactggc aacccggcac
     3721 ttgttcaccg tcacgcaatg tcgtgtcgaa aataaataat ctgtctgaca tagttcttat
     3781 cgtcttaaat ttgttaatat cttttctgaa tgaaaaaagc ctctctcaca aggaagcgag
     3841 aaaggctttt tcatatctta atgccctgta aagcatacac agtctcactt cctattccgt
     3901 ttccagagta gaataatgtt tagagaaata atgagactat ttagcattac ctgtttcata
     3961 ttgtcttttc aaccgttttt gtttgaacgc tgcaaagata cggtcttttt ccaaacaacc
     4021 aaatataatt taaagttttt atcactattt tcttataaaa tagaagacaa atacacctaa
     4081 attcttcaat tcataaccaa taatctactt atcatttttc aaggcttctt tatggagaat
     4141 tgatccacca ctttcccgtc cacatctacg acctgtattt ttagttcttt cggatcggca
     4201 gccgctttca aaatagctgt attggaattg acgataatcg ggaacggtgt acgatccgtt
     4261 gcatcctgat ggatgaaacg gtggaggtga ccacacaaca taacgtccgg cttggcatcg
     4321 cgtagcaaag gcatgaattt ctgctccact tccaagtttc catgccatcc gccgatcggt
     4381 gggatatggg ctacgataat tttaaacggc gcgtccttat attctttgct atccaatacc
     4441 cggcgcaacc attcggcttg ttctgtccgg tattcgtcgt agactgttat accggcatat
     4501 tcaatatcgg aatccggctt gtcctctccc gtatccaaaa tgacaaaaca gatcggacct
     4561 tgccggaatg tatagtagat attctcttct tttgcagaga aatagcgttg aaactcggtt
     4621 gcaaaagcgc cacgtgtttc gtggttgcct cttgtataat acatcggaat ttcagaggca
     4681 aacagcttgg tcgccgtatc cataaaaccg tcgaagatat gattttcctc attgaagacc
     4741 gacaccatat caccgttaaa aagaaaaaag tccgtctttt tcaaatcaca cttggaaact
     4801 aggttcgtca acaggtcatt tttgccatgt atatcgttca ccatcgcaaa tgagacggaa
     4861 ttatccgcag gatcgctcgt cttgaacacc aacggctttt tggagtaaac atcagtcgag
     4921 gcatagttcc catagatgat cttatgtccg acatggctca atacttcctg tacgaagaca
     4981 cgataacggt agttcgtacc cggtttaagc cctttgatct tcacggtatg gatcgtagat
     5041 gtatttttta ctccgttacg ggcatcataa tatttgggac gttcggtagc ataaaagttc
     5101 gtatcgtcat ccggcgccag ctccacccaa ccgacagaag gtttatccga caaccacacg
     5161 atcgtcacct catcaggccc tagattctgc aaataaggac catgcaccaa ccgaatcttc
     5221 gactctactg ctcctgctag acaaacagac agccacaata acattactaa aatttggaat
     5281 ttcttcatga tataatattt aagcaattaa attcgaattt atagctacga agatatcgat
     5341 tactattcaa aaatttctta tcaaaatgat acattttcat taaaaaaagt gacaattcat
     5401 accgaattgc cactttcttt atgcactcaa ataaaaaatg cgatgtctat caattgtttt
     5461 ccgggcgcaa tttacgaacg actgcacctg cacgccacat ttcgctttcg cgcaatgctg
     5521 ccagttcttt ttccaaacct tcacgataat ccggcttact gttcgtatcg atagaacgct
     5581 gcgcttcgtt accgcaggcg acctcccggt ataatttttc aaatacaggc ttaacggcat
     5641 cgtggaacgg ccccatccag tctaaagcgc cacgctgtgc agtagtcgaa cagtttgcat
     5701 acatccagtc cattccgttt tcagcaaaca gcggcatcaa agactgagtc agctcttcga
     5761 ctgtttcgtt gaatgcttcg gaaggttcgt ggccgttttc acgcaatgtt tcgtattgag
     5821 ccaacaataa accttggata gcccccatca aagttccacg ttcaccagtc agatcggaat
     5881 aaacttcctt cttgaatgtc gtttcgaaca gatagcctga accaacgccg atacccaaag
     5941 cgatcacacg atcccatgct ctaccggttg catcctggaa aattgcatag cttgaattca
     6001 agccacgtcc ctgcaggaac atacgacgca aagaagtacc agaacctttc ggtgcgacta
     6061 gaatcacgtc aacatcagca ggagggataa tattggtacg ttccttgtaa gtgatagcaa
     6121 aaccatgaga gaaatacagc gcttttcccg gagtcagata ttttttgata cgcggccagc
     6181 attcgatctg agcggcgtcg gaaagcaaca cctgtatgat agttgctctt tcgcaagctt
     6241 cttcaatacc gaacagtgtt tcacccggta cccagccgtc ggcaacagct ttgtcatagg
     6301 ttttaccagg acgctgtcct acgataacgt tgaaaccatt atcacgcaag ttcaagctct
     6361 gtccaggacc ttgaacaccg taaccgataa ctgcaatcac ttcatctttc aatacttctc
     6421 ttgccttttc caacggaaat tcttcgcggg ttactacgtt ttcgtcaaca ccgccaaaat
     6481 tcattactgc cattttttct actattaaat gtaatgtgtt aataaaataa ttcttttgtc
     6541 aggacagttc gcaaaccatc cgcccgtacc atgtttgttc aatgccacat aacagcagca
     6601 cggcaaatcg ctttgccttc attacagatc gccatatcat attttccgtt atcagcctcc
     6661 ctcttgtaca acatgagttt catcccatat ttgccttcag actggtaggc gatttcgaaa
     6721 cgtttgatat cttttgtctt gaacaggtct agatcaaaca ggtctagaag atgttccata
     6781 tacttgatac tgttcaggtg gccgttgata tcaaggtcgc tgtacttaat gaaataagga
     6841 accccttccg tctcattctc cacagccgca atctttcccg gcttttctat cgggcagggg
     6901 cgatccgtga cataagcgct caacctggcg atatccaaca aggtcggccg gcgtgtttcc
     6961 acatcgatag ccgcccaaat agaacgggcg taaccgaatg tcttaccgtt gccatccacc
     7021 agctcgaaac aacggctggt aaagaggcgg ccgacttcat ccacccaggt ataaagagtt
     7081 ataggttcgg acatggctgg atattcgatc atttcgatcg ccagacggga aagaacccaa
     7141 gccgtatgcc gttctgacat atcgttgaaa ccgaatccgc gttcagcagc atggctggat
     7201 gcgacatgta tcagatagtt tccgatcatc ggtatcgtta cacgtccacg aaaatccaac
     7261 aggtacggtt ccgtgacgaa atgaaattcc cctattttgc ttttatcttt atccatggtt
     7321 cttttctgtt ggggcagttc gcaaaccacc cgtacgttat ttttttttcc tgcaacttac
     7381 gttccatttc ggccaacata tcgctcaaac gttcgacacg gctttttgtg atcgcaacgc
     7441 gaccggaacg gatgaactgc aagacaccga tcgtttcgct caactccctg aaaagggctt
     7501 gcgtctcatc gtaatgacca ctcttttcga gaacgacaca cgtttcgttc atttccagaa
     7561 tacgggcgtt atatttgcga atcagatcct cgaccgtccc catcttgata aacaactcgg
     7621 tgctcagctt ataaagggcg atctcctgga aaaccagatc ttcatccgta ttatagtaag
     7681 ccttcaagat atccacccgt ttgtcgatct gcttcacaac cttgtcgatc atatcttcat
     7741 cggcaaatgt cgtgattgta aatttatgta taccctgtat ggcggaaggt gaaacggaaa
     7801 gcgtctcgat gttcaactgc cgacgcgtaa agataatcgt aatctggttc agaagaccta
     7861 ctgtattctc tgaaaagata ataacggtat ataatttttt tgttgtcata gcttcacctc
     7921 cttacttatc tcctaatatc atgttcgtta cgcttcctcc ggcaggcacc atcggatata
     7981 ccataccaca cgtttccaca ttggcgacca acacaaacgc tccgttatgg ttcaacatct
     8041 cggcaatagc ctcatccagt tcctcccgtt tttcaacggt acggacagcg ataccgtacg
     8101 ctttcgcgat cgccacgaaa tccgggttct ccatgatcgt attcgaataa cgttcgtgga
     8161 agaacaactc ctgccactga cgtaccattc ctaagaaatt attattgagg ataatgattt
     8221 tcacatccag tttttcctgc ataatggttc ccaactcctg aatcgtcatc tgcatcccac
     8281 cgtcaccggt aaagaagcag accgtacggt caggtgcacc gaacttggct cccatagcag
     8341 cgggaaggcc aaagcccatc gtccccagac cacctgaagt aaccacgcta cgagtgcgtt
     8401 tatatttgaa atagcggaca cccatcatct ggttctgtcc gacatccgta actaaaacag
     8461 catcgtttcc ggtcgcctcg gacacttttc gaacgacttc acccattttc aaagatccgt
     8521 tcatcggata caactccttc tcgatcacct tttcatactc ttcctgtgca tccggctcaa
     8581 actcagcatt ccactccgga cgtttccgtt cttccaacaa cgcagttatc atcggaatgg
     8641 tatgtttggc atttccgaga accttcacat cgaccgatac attcttcccg atctccgagt
     8701 tgtcgatatc caaatggatc actttcgcct gcttggcgta tgtcttcaaa tcgccagtaa
     8761 cacgatcgtc gaaacgcata ccgatggcga tcaacacgtc acattcattg gtcttcctgt
     8821 tcggaccgac attgccgtgc atacccaaca tacccttatt caaaggaaaa tcggaaggca
     8881 acgccgatag accgagaaca gtcgaaccgg caggaatgtc attcttcaac aggaatgctt
     8941 tcagctcctc ttcagcacct cccaacagaa caccctgtcc gaccaggcag aacggtttct
     9001 ccgctttatt gatcaacgcg gcagccgctt taatccgatc ctggttgata tccggttccg
     9061 gctgatagct gcggatatag tctactttct tatattcata atccacaaat ccaacctgag
     9121 catcctttgc caaatcgagt acaacaggcc ccggccgtcc ggtagaagcg atataaaaag
     9181 cacgtgaaac agcccacgct atctcttccg gcttgcgaat ctggtacgcc catttggtga
     9241 tcggttgcgt aatgccgatc acatcgactt cctggaaagc atctgttcca agcaatggag
     9301 aagggacctg tccggctatg accaccatag gcgtgctgtc catcagtgca tcggcaatgc
     9361 cggtgatggt atttgttgcg ccgggtcctg aagtaaccaa cgtcacccct actttaccgg
     9421 atacacgggc atacccttgt gcagcatgcg tcgccccttg ttcatgacgc accaatacat
     9481 gcttcaattt atccctgtaa tcgtacaaac tatcgtaaat aggaatcgct tgcccgccgg
     9541 gataaccgaa aatcgtatct actccttcag ctatcagtga cttcagcaaa gcttccgaac
     9601 cggttatctt ctgtttctcc atatctcttt attttagtct tgtgtttaat cttctactac
     9661 tctcactcca cccttatcgg ccgaactgac catcttaccg taagctctca aggcttttga
     9721 gacgacacgc tggcgatgag gcggcgtaaa ggcttttgtg ccgcgggctt cttccgcttt
     9781 acggcgttct gccaactctt catcgcttac cttcacatta atcgtacgtt cagggatatc
     9841 aatctcgatt atatcgccgt ctttcaccag tccaatcgct cctcctgccg cagcttcggg
     9901 agaaatatga ccgatagaaa gaccggaagt accgccactg aaacgaccgt ctgtgatcag
     9961 cgcgcactcc ttgcctaaat ggcggctttt tatataagaa gtaggataaa gcatttcctg
    10021 catacccgga ccacccttcg gtccttcgtg tgtgatcacc accacatcgc ccgagacgac
    10081 ttttccaccg aggatgcctt cgcaagccgc atcctgcgaa tcgaacactt tcgccggacc
    10141 ggcaaacttc cagatgcttt catccacacc ggccgtcttg accacacaac cgtccagcgc
    10201 gatatttcct ttcaggacag ccaggccgcc atctttggaa taagcatgct cgatatcacg
    10261 gatacatccg gcggcacgat cggtatccag ttccttataa taggtttcct gcgatcccat
    10321 ccgaatgctg aaacgatggg cgggagcgct cttgtatttc ttgacagcct cgtccgtcac
    10381 attcggcgag gtgatagcaa atttatccac agcttcggca agcgtcattc cgtccacacg
    10441 cttcacattc ccgtctacca agccgttttt cagcagctcg ttcatgattc ccatgatacc
    10501 accggcacgg ttcacatcct ggacgtggta ggtatgcgtg ttgggagcaa ccttgcagag
    10561 gcaaggagtc ttgcgggaga gcatatcgat atcgtccatc gtgaagcccg cctcagcttc
    10621 ctgcgcgatg gcgagcaagt ggagaaccgt attggtggaa ccacccattg caatatccaa
    10681 tgacatggca ttcaggaa
//
