LOCUS       c00065_gnlPro..        14859 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PEPJJACL_65.
ACCESSION   c00065_gnlPro..
VERSION     c00065_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:32:28
            Original ID  :: gnl|Prokka|PEPJJACL_65
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14859
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14859
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1419:4859]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1420..4859
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14859
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14859
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             3..98
                     /locus_tag="ctg65_1"
                     /transl_table=11
                     /translation="TPGSYALIDPGVGGGYMGVLGKFYYVFFIDL"
     CDS             complement(207..1160)
                     /locus_tag="ctg65_2"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPAPGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             1420..2094
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_3"
                     /sec_met_domain="SucD_FumR (E-value: 1.4e-66, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             2133..4076
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_4"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.4e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.2e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             4104..4859
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_5"
                     /sec_met_domain="Fer2_3 (E-value: 1.4e-25, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 4.1e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.4e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             5054..5212
                     /locus_tag="ctg65_6"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5185..6216)
                     /locus_tag="ctg65_7"
                     /transl_table=11
                     /translation="MKIGTIDLGERPIFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDISREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLDILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             6597..7856
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_8"
                     /sec_met_domain="Peptidase_U32 (E-value: 1.9e-68, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNN
                     FTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAM
                     NYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITG
                     PKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIEL
                     DIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNG
                     TFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDK
                     IGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEK
                     IRPSDRLYKMEKVQLEKVFE"
     CDS             7856..8263
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_9"
                     /sec_met_domain="HBT (E-value: 2.7e-08, bitscore: 27.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 4.2e-09, bitscore: 30.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             8260..9375
                     /locus_tag="ctg65_10"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRIGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATSVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
     CDS             complement(9626..10516)
                     /locus_tag="ctg65_11"
                     /transl_table=11
                     /translation="MLSFILVLLLGGFMPAGNLLASDKEQNPHYITVKNSRDLQAYFRY
                     APDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLIHDETID
                     RTTTGKGKVSDYTYAELQQFNLVDRNGNVTAFKIPTLKECLEWSKGKTILNLDIKDVPL
                     EVMADFIETEKPVNVMYTVHNASQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPWKQ
                     VMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYRSEISTRPDVI
                     ETDYPYLFQGLDLTK"
     CDS             11124..11486
                     /locus_tag="ctg65_12"
                     /transl_table=11
                     /translation="MERLTRQEEDVMRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVK
                     NLERKKYVKAKRYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKIS
                     TDELKEIIDMIEKGRE"
     CDS             11507..13243
                     /locus_tag="ctg65_13"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLPGISYLYWS
                     GVIALSFRFLVQLSSILLLARRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDEILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPV
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREEYVLSEEGI
                     EAARRARNQVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKNGIEGRVSCSFVVGKD
                     GAISEAEVIRGVSPELNEEALRVINSMPVWSPGKQRGKVVNVKYTVPVTFRLSGGKKKT
                     SSRIVQRQIKEVDTSGRVFTVVQQMPEFPSGQASLLKYLATRIKYPAIAQENGIQGRVS
                     CSFVVDTDGSLKNIEVIRGIDPSLDREAVRMIREMPKWNPGVQNNMAVAVKYTVPVTFR
                     LQ"
     CDS             13277..14830
                     /locus_tag="ctg65_14"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYQCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTGLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLGKTYDRKRAYELFDLAETNMQPKKFLVNMLTTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNADEVTMLAPDGKKTKLAVADLRALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSGAKLDTLALSKEEKEKARKMLKDADLE
                     "
ORIGIN
        1 cgacacccgg atcttacgct cttatagatc cgggtgtcgg gggcggatac atgggggtgt
       61 tgggtaagtt ttattacgtg tttttcattg atttgtagct gtatttacat aaaagagcct
      121 tgtctttgat gatataggag aacaagccct ttttcctttt cttgtttacc ttgccctgca
      181 aattgtcagc ttgttttagt agaaattcaa tcacgttcga aatcggacag cacttctgcc
      241 gtagtagcgt tgatgttctt gtccaataca taaatgcggt aagacaggct cagttcttta
      301 ccgggttcca atgtgaatgc cttctgcttg gtcggtgaga aattccacat gacgtcaccg
      361 gcaggcttgt tgactgtttt gtcccatacg cgtaaaggct caggatagtt caggttggaa
      421 ggggaggcaa cgattaggat acaggccttt tcgtttccgg ctttcccttg gtagtagcac
      481 caacgggctc tcgaaccgtc agcttcgtcg cgggaaaggc cttccgaggt gagcatttcg
      541 gctgtctgat cgttccagtc ttcgcgcgta cggatgcata tgccgccata acggtaagct
      601 tccatggtga tcgggctagg gctggcgagg cggatagtgg tatgatagtc gatgtaataa
      661 cctggtaagg atgttgtccc gatgttgatc tccaggcgtt cgttcattgc tactttttct
      721 gcgggagaat cggggtagac cacatggtcc agtgtcgcaa caaaaccgtt gtcggatacg
      781 tgttcgaagt tgcggaagcg aactgttcct tgttttttgt ggagattcca gaaatcgatc
      841 tcgtttcctt cgaacgtggt tttcgtccag gcataccaca aaccgaaatg atggtaatgg
      901 tcggcgggag aacaattggt catcacttcg cctcccaatg tcttcaaagg atggatgaaa
      961 ccgctgcgtt tatagaccga gtcaacgcca ggggctgggt aaaccgtggt atagttgtaa
     1021 gagaacaaca gtttatctcc tatcttatag tctaaggttt tccccgtgtc gacgacggaa
     1081 caggatgttt cggaaggctg acaagagcct aagaacagag aaatcaaaaa aacaccaata
     1141 gaaaaaatag cagttttcat aatatgacaa ttaaataata atcagttatc cggcaagacc
     1201 ttgcctgtat cggctacaaa aaaacgaaat tttttcattt cgcacaatcc gtttgtgata
     1261 tctgatgcaa ataaaaccag ccagcaagca gtgttctaat tgatgaaata tttctttaat
     1321 cgtttgcgtg atatggggat ttagcatacc tttgcacgat aataaccata gattggagga
     1381 aatttctaaa tacaattaaa taacttaaat tattatctta tgtggttact taattcttct
     1441 atcgggaaga agctgataat gagtatatca ggtctttttc tcattctgtt cttggtgttc
     1501 cacttatgta tgaacattgc ggcagtattt tctggtgaag cgtataacgt gatttgcggt
     1561 ttgctgggtt ctaactggta tgctttgctc ggtacattgg tgttggctgc aggtgtagtc
     1621 gtgcacttcg tgtatgctat tatcttgact ctgcagaatc gtaaggctcg cggtaacgac
     1681 cgttatgcca tcaacgctcg tccgaaaggt gttgaatggg cttctcagaa catgtttgtt
     1741 ttgggtgtga tcgttatcct gttcatggtt ctgcacttta ctcagttctg gtacaacatg
     1801 atgtttgccg aactggcagg tattcatggt gacattcatc cgcaggatgg tgcagcgttt
     1861 atcaatttct acttccaggg caatgttgtg aatacggtgt tgtatctgat ctggttcgtt
     1921 gctctgtggt ttcacctgac tcacggtttc tggtctgcga ttcacacaat tggctggaac
     1981 aataccgttt ggttaagccg ttgggaatgt atctctaaat gggttgccac tattatttgt
     2041 ggcttattcg ctgttatcac agttatcttc tacctgaacg gtgtaggtgc ttaatttcgg
     2101 atattatttt ttcaatttga aaataaaaca ttatgactca aatagattct aaaattcctc
     2161 aaggcccgtt ggctgagaag tggacaaatt ataaaaatca ccagaaattg gtgaatcccg
     2221 caaacaaacg tcgtttggac ataattgtag taggtactgg tctggcgggt gcttctgctg
     2281 ctgcctctct ggctgaaatg ggattcaatg tattgaattt ctgtattcag gactctcccc
     2341 gtcgtgcaca ctctatcgct gcacagggcg gtatcaatgc ggcaaagaat tatcagaatg
     2401 atggtgactc ggtttatcgt ctgttctacg atacaatcaa aggtggtgac taccgtgccc
     2461 gcgaagcaaa cgtctatcgt ctggctgaag tgtcaaactc tattatcgac cagtgtgtgg
     2521 cacagggtgt accattcgct cgcgaatatg gtggtctgtt ggataaccgc tcattcggtg
     2581 gtgctcaggt atcccgtacg ttctatgccc gtggtcagac cggacagcag ctgctgttgg
     2641 gtgcttactc tgcattgagt cgtcagattg gtttgggaaa ggtgaagatg tacacacgcc
     2701 atgaaatgct ggatgttgtg aaggttgacg gacgtgctcg cggtattatt gcccgtaatt
     2761 tgattaccgg taagatcgaa cgttttgccg ctcacgcagt cgttgttgcg acaggtggtt
     2821 atgtaaatac attcttcttg tctactaacg cgatggcgtc taacggttct gctgcatggc
     2881 agtgctacaa gaaaggggct tactttgcta atccttgtat ggtgcagatc cacccgactt
     2941 gtgtgccggt gaaaggtgac ttccagtcta aactgacttt gatgtcagaa tcactgcgta
     3001 acgatggtcg catctgggtt ccgaagaaac tggaagatgc gaaggcattg caggccggaa
     3061 caaaaaaggg aaaggatatt cctgaagcag atcgcgacta ctatctggaa cgtcgttatc
     3121 cggcattcgg taacttggtt cctcgtgatg tggcttcacg tgccgctaaa gaacgttgtg
     3181 atgccggttt cggtgtaaat agcacgggct tggcggtatt cctggatttc tccgacgcta
     3241 tcaaccgttt gggtaaggaa gtggttaaac agaaatatgg taacctgttc gatatgtacg
     3301 aagagatcac gaacgatgat ccgtacgaaa ctccgatgat gatttatcct gcattgcact
     3361 actcaatggg tggtttgtgg gtagactatg aattgatgac ttctattccg gggctgttcg
     3421 caatcggtga agccaacttc tctgaccacg gcgctaaccg tctgggtgct tctgctttga
     3481 tgcagggatt ggctgatggt tactttgtat tgccttacac gatccagaac tatctgtctg
     3541 accagatcca ggttccgcgc ttcagcactg acctgcctga atttgtggaa gcagaaaagg
     3601 ctattaacgc ccgtatcgcg aagttgatga acgtgaaggg taaagaaaca gtcgattcta
     3661 tccaccgtaa gctgggacat atcatgtggg aacacgtcgg tatggcacgc gacgcggaag
     3721 gcttgaaaga agctatccaa atgttgaaag acctgaagaa ggaattctgg agcaatgtat
     3781 tcattccggg tgaagcgaac agcttgaacg tggaattgga caaggcattg cgtttggctg
     3841 actttatcga aatcggtgca ttgatggcac acgatgcgtt agaccgcgca gaatcttgtg
     3901 gtggccactt ccgtacggaa catcagaccg aagaaggcga agctatgcgt catgacgata
     3961 agttcatgta cgtctcttgt tgggaatacc agggtgaaga caaagacccg gttatgctga
     4021 aggaagattt gaactatcag ttcgttgttc ctcaaacacg taactacaag aagtaataat
     4081 catcaatcac aaaaattaga atcatggata aagatataaa ggtaacactt aaagtttggc
     4141 gtcagaaagg tccgaaagat aaaggacagt ttgagactta ccaaatcgac aaaatcaatc
     4201 agagtgtttc tttcttggaa atgttagaca ttttgaatga acgtttggtt agcgaaggca
     4261 aagaacctat cgtattcgac cacgactgcc gtgaaggtat ctgcggtatg tgttcattgt
     4321 atgtaaacgg acatccgcac ggaccggcaa caggtgcaac aacctgtcag ctctatatgc
     4381 gccgtttcaa tgatggtgag acgattacga tcgagccgtg gcgttctgcc ggtttcccgg
     4441 taatccgcga cttgatggta gaccgttatg cttatgataa gattatccag gcaggtggtt
     4501 tcgtttctgt aaacacaggt ggggttcctg atgctaatgc aattcctatt tctaaggctg
     4561 atgcggattt ggctatggat gctgctgctt gtatcggctg cggtgcttgt gctgctgctt
     4621 gtaagaacgg ttcagctatg ctgttcgtct ctgcaaaggt tagccagctg gctcttttgc
     4681 ctcagggtaa ggtggaagct gctcgtcgtg caaaagcaat ggttgctaag atggatgaac
     4741 tgggctttgg taactgtacg aacactcgtg cttgcgaaat ggaatgtccg aagaacatct
     4801 ccgttagcaa catcgctcgc ttgaaccgcg agttcatctc tgctaagtta caagactaat
     4861 acattatata tatatatgta tatggaaaag ctcgtcgcca atggcaacgg gctttcttta
     4921 tgttcgttca aacccacaaa aaagccgcac tccctataat aaaagtggat gcggcttttt
     4981 tgttgctttc cagtgaaaca gtctctcgat tccctctctg caaagacttt gttaacctta
     5041 gatctaaaat actatgaaaa aaactcactg caaatataaa gtatatttac tgaatacgca
     5101 agagtttgta attacatttt attgcaaatt tgctactttt tgttttaaaa ttgacactgt
     5161 gtgcggattc acactgttat tatatcaaca atcgatcgat tctgacactt gagagtcact
     5221 ttgaaatccg tatcctgtat gaaatttgtc ggggatggaa tccagaatgt cgaataatgc
     5281 ttccactgtt tccgcacgta gcatggcgac gcgtgtctgc ttgaagtctg caataccttt
     5341 aaacagcgga gttgcagcca aatggcggcg aatgtggaga attccccggc gctcatccaa
     5401 acgttccacg ctttgttcca cctgcttttt cagtatgtcc agataccatg aaaaagattc
     5461 ggcaggcaat gtctcgcctg tatccagata atgcctcact tctctgaaaa tccaggggcg
     5521 gcctatgctg ccccggccaa tcataacggc atccacgcca tattgttcga aacgttgttt
     5581 gcagatttcg gcggaagtca catcgccatt gccgatgatg ggaatttgta tgcggggatt
     5641 gttttttact tcaccgatca gtgtccagtc tgcctctcct gtgtacatct gtgcccgggt
     5701 acgtccgtgg atggaaaggg ctgcgatacc gcaatcctgt agctgttcgg ccaagtctac
     5761 gatgatccgg ttgtcggcat cccagcccaa gcgggttttt acggtgacag ggatgttcac
     5821 cgctttgacg acttcacggc tgatgtccag catcagtgga atattgcgca gcatgccggc
     5881 gcctgctcct ttgcctgcca ctcgtttgac agggcaaccg aaattgatat cgagaatgtc
     5941 cggatgagcg gcttcgcaaa tttgcgcggc ttcgaccatt gtcggaacat cacggccata
     6001 tatttgtatg gcgaccggac gttcttcatc cgccacattc agcttttgct gtgttttatt
     6061 tacactgcgg atcagggcgt ctgctgaaac gaattcggta taaaccatat cggcaccaaa
     6121 acgtttgcac atcaaccgga aagaaatatc tgtaacgtct tccatcggag ctaagaagat
     6181 ggggcgttcg cctaaatcta ttgtacctat tttcatattt atattatcaa tgacggggac
     6241 aaaggtactg atttcctgct aaaaacaggg ataaaaggat atctactaaa aaatgtagta
     6301 attgatcaat aaaaagtaca aatgtcatac tgtcaatgat ataggtaaaa tgataagctg
     6361 aaatcatgat agttacatga tagtagtatg atagttaaaa atagaaacta tcatgtctta
     6421 aggtattgaa taacaggttc taaaggacaa caatgacagt atgatggttg ttttgcaaat
     6481 ctttatagaa aatggtattt gatcacgatt ttgatgctct gagaaacgga tacccatgca
     6541 attcttctcg gatattattc ctacctttgc gaacgaacca gtaaatgtat aagaacttga
     6601 acgagaaaga ttttgaaata atggcgcctg tcggttcgta cgaatcactg atggcggcta
     6661 tccaaggggg agccgattct atctatttcg gtatcgaagg attgaatatg cgttcgcgct
     6721 cttccaataa ctttacgaca gacgatttgc gcaagatcgt tgcgctttgt cgtgagcacg
     6781 gtattaagag ctatttgacc gtcaatacgg ttatttatgg ggaagacctg cctctgatgc
     6841 gcgagattat cgatgcggcg aaggaggcgg aagtttcagc gatcattgcg gccgatgtgg
     6901 cagctatgaa ctatgccaac agcatcggac aggaggtgca tctttccaca cagctcaaca
     6961 tttccaatgc ggaagcactg aaattctatg cccgttttgc cgatgttgtc gtcttggcgc
     7021 gtgagctgaa tttgaaacag gtgcatgaaa tctatcggca gatcgtcgac cagcagatta
     7081 cgggaccgaa aggagaactg atccgtatcg aaatgtttgc ccacggagct ctctgtatgg
     7141 ccgtttccgg taaatgttac ctgagcctgc acgaaatgaa cgcttccgcc aaccggggag
     7201 cttgcatgca gatttgtcgg cgtgcttatt cggtaaaaga taaagacagc aatatcgaac
     7261 tggatatcga aaaccagtat attatgtcgc ctaaagacct taagacaatt catttcatga
     7321 ataagatgat ggatgcaggt gtacgggtat tcaagatcga aggacgtgcc cgcggtcccg
     7381 aatatgtccg cctggtgacc gaatgctata aggaagctgt gcgtgcttat tgcaatggca
     7441 cgttcgatga aaagaaagtt gccgcttggg acgaacgcct gcgcagtgtg ttcaaccgag
     7501 gattctggga cggctattat ttggggcaac ggttgggtga gtggagtagc aaatatggct
     7561 ccggcgcgac taagaagaaa gtgtatgttg ccaaaggaat caaatatttc gacaagatcg
     7621 gcgtggcgga gttcgaaatg gaatccggta acctgaaagt gggtgatgag atcctgatta
     7681 ccggaccgac aacgggtgcg gttatgcaga cgatagaaga aatccgtgtg gacttgaagc
     7741 cggtggacga gaccgttaaa ggtgaacggt tctctctcaa ggtgaacgag aagattcggc
     7801 cgtctgaccg attgtataaa atggaaaagg ttcaacttga aaaggtattt gaataatgaa
     7861 agagtatatt tttaaactga cagacaaggt ccgtgactac gaatgcgacc tgcaaggagt
     7921 ggtcaacaac tccaattatc agcattatat ggaacatact cggcatgaat tcttggagtc
     7981 gcttggcgag aacttcggaa agatgcacga aaaaggggtt gacggatttg tatcgcgggt
     8041 agaaatccag tataagacct cgctcaagag cggcgacagc tatatctctt gcctcaatgt
     8101 ctataaaaaa ggagtcaagc tcgtattcga gcaggatata tatagggctt ctgacaatgc
     8161 attggcgacg aaaggaatcg tcgagtcggt tatcgttgag aacggaaagt tgacacgcgg
     8221 tgaatatttc gacgaaatgc taaaaagaat agaacataca tgactgacaa acggatttac
     8281 caaatcggcc ttactatgat aaacggcgtg ggagatatcc tggcgcgtca tctcctgcag
     8341 gctttgggag aagcagaggc tgtgtttact gaaaaacaac agttgttagg aaggatccct
     8401 ggtatcggca gcaatattgc tgccgaaatc aaacgcccgg aaatcttgca acgggcggaa
     8461 aaagagttgg cttttatcga gaaaaacaat atttcctgtt attatctgac tgatacagat
     8521 tatccggtgc gcttgagaga atgtccggat gcccctatac ttttctattt taagggaaat
     8581 actaaccttg atgcgacccg tatcatcagt attgtgggta ctcgcaacgc gaccgaatat
     8641 ggtcgggagc ttaccgaatc ccttataaaa gacttggcaa aagtgatccc ggacttgttg
     8701 gtcgtgagtg gattggctta cggcatcgat atctgtgccc accggaacgc tttgtacaac
     8761 cgacttccga ctgttgctgt gctggcgcat ggcttggatc gtatctatcc ttcctgccat
     8821 cggaatacgg ctgtcgaaat gctggaatcg ggcggtctgt tgaccgattt tcccagcggt
     8881 acagaaccag accgtccaaa tttcctccgg aggaaccgga ttgtcgccgg aatctcggat
     8941 tgtacgatcg tggttgaatc ggcagaaaaa ggaggctctt tggtaactgc cgatattgca
     9001 ttctcttatg gccgggatgt ctatagcttt ccagggcgca tcggtgacag ccattccaaa
     9061 ggatgcaaca atttgatccg acaaaataaa gccggcctga tcacttctgc ggacgatctg
     9121 ctctccgctc tttgttggga tatccaagct ggggctactt ccgttcaaac ggagttgttt
     9181 ttcgccgagg cggaaacatt cacctcggaa caaaatccgg ttttagccat tatgcgaacg
     9241 cggaatgaga tccatatcaa cgagcttgcc tcagtgttgg agataccggt acatcaactc
     9301 tctatgctat tgttcgaact ggaaataaac gggaaggtaa aagcgttgcc gggaaatctc
     9361 tataagctgt cctgaccggc tttttcgtat acgatttgta tgtgggagaa gaaacggaac
     9421 ctctataaac aattaaaggc tgtctcacga caacccctaa ccaactttgt taaccttaaa
     9481 tctaatacta ttatgaaaaa accacattgc aaagatacac tcgtcaagag cgtttgtcaa
     9541 gcattttgtc gctaatactt gttaatcaga tgagcataaa tagcaaaaag attttaatcg
     9601 gctataaaga gtcctttaaa ctgcgttatt ttgttaaatc gagtccttga aacaggtacg
     9661 gatagtccgt ttcgatcacg tcgggacgag tgctgatctc tgaccggtaa ccggcggttt
     9721 tctctgtttc cgttttcgcg cgatcatgtg tcggagcaac ggaaatcatg cacatgactc
     9781 cgttacggtg cagagcgtca tacagtggtt gctgttcagg cttcatcttc gggcctacat
     9841 aagccattac ctgtttccag gggatgccgg ctttttcata attatcgaat tcttcccgat
     9901 tcttacacca gcaagaaaac atcgcatccg gtttccggtc gagataatag cgggcttgac
     9961 tggcgttatg taccgtgtac atgacgttaa caggcttttc tgtttctata aaatcagcca
    10021 taacttctaa aggtacatcc ttgatatcca aattcaggat tgttttgcct ttgctccatt
    10081 ccaggcattc ttttaaagtt ggaattttga aggctgtcac gttgccgttt cggtccacca
    10141 gattgaattg ttgcagttct gcataagtgt aatctgaaac ctttcctttc ccggtagttg
    10201 tccggtcgat ggtttcgtcg tgtatcaata cgattatccc gtcttttgtc aaacgcggat
    10261 ctatctcgaa aaacgattcc atataggaca aggtcttttc gaatgattcg atgcagttct
    10321 ccggatagcc gtctagcatt ccaccacgat gtccactgat tacaatcggg cgatcgggag
    10381 cataccggaa ataggcttgt agatcccggc tgttcttcac agtaatgtaa tgaggatttt
    10441 gttctttgtc tgaagccaaa agattcccgg caggcataaa accccctaaa aggagtacca
    10501 aaataaaaga tagcattttc atgatattgt atttatatag attctttgtc aattatgcgg
    10561 cttaaaagta agactttttt atcagtggcg tactataaaa gcactataaa aacatgaaaa
    10621 tatgacaggc aacaagatgt gcaaagaaag aggcaggtat ataaaaaatt aaggattgtc
    10681 atctcgacaa cccctaacca actttgttaa ccttaaatct aatactatta tgaaaaaacc
    10741 acaatgcaaa aatacactag ctaagcttgt ttgtcaaacc ttttacggat aatatatgtt
    10801 aagctctaat agctattttg tcaaaaaatg ttggttattt ataaactata cagattccat
    10861 gtaaaaactg ctaattcaaa tactttttat cgtcggaaaa agtgaaatcc catgcttaaa
    10921 aagtgtcccc ttggagtata taaaatcatt aattaatata ggggatgctt tggtgtggct
    10981 gcttatagat aaattccttt ttggcgcatg cagcgaatag atgatagatt attaattgtt
    11041 aatacaaatt aacgcattat ttcttgcata tttacgatgt attcgtagat ttgcgatacg
    11101 atcgtaaaaa ataatataga aacatggaaa gattaacaag acaggaagag gatgtaatgc
    11161 gctggatctg gcagatcgag ccgtgtttta tcaaagacat cctggcgaag tatgaagagc
    11221 ctaagcctcc ttatacgaca ctcgcttcta ttgtgaagaa tctggaacgt aagaaatacg
    11281 tgaaagcgaa acgttacgga aatacttacg aatacaggcc gctgatccca caggaggaat
    11341 ataaacggac gtttatggga agtgtggtga acaactattt cgagaactct tacaaggaaa
    11401 tggtctcctt ttttgctaaa gaacagaaga tatcgaccga tgagttgaaa gagattatcg
    11461 atatgattga aaaaggacga gaataaactg ttaaatacat aatgccatga caccggaatt
    11521 tgcctacttc ttgaaggtaa atgtagcttt tatactcctt tatgccttct accggctgtt
    11581 cttttataag gacaccttct ttaaactacg ccgtaccatc ttgttggcat ttttcggggt
    11641 gtcattgctt tatccgctga tgaatattca ggattggatc cgggagcagg ggccgatagt
    11701 ggaagtcata caaatgtatt cagccatttt gcccgaaacg acaataaccc ccggcaatgt
    11761 tccccaaaca aattggcatg atttgttact tcccggtatt tcttatcttt attggagcgg
    11821 tgtaattgcc ttatcgttcc gttttttagt gcagttgagc agcatcttgt tactggcacg
    11881 gcggtcggaa gtgactttga tccgtaacgt acgtgtacat ctgttgaata aaccggccgg
    11941 tcctttttct tttttccggc tggtatttct gcatcccgac agccattccg agaaagagat
    12001 cgatgagatt ttggtacacg agtgtacgca tgtcagccag tggcattcga ttgacgtgat
    12061 tatttgcgaa ttggtttgta tcatctgttg ggtgaatccg tttgtctggc tgttgaaaag
    12121 agaggtacgt cataatctgg aatatttggc ggatgatacg gtacttgaat cgggctatga
    12181 cagtcgtagc taccaatatc accttttggg gttggcacat accaatagat cggtgacctc
    12241 tttatctaat aactttaata tgctgcatct gaaaaatcgg atcagcatga tgaataagaa
    12301 acgttcccgg agcataggta ggacgaaata cttgattttt ataccggttg tgggcgcctt
    12361 gctgatttta agcaatgtcg atgcattggc ccggatcacg gacgaactga cggaaagcac
    12421 gtttgccgat gtcttgctac cggaggctat cttgccgttc ccttttgtcg gtgatgcttc
    12481 tcctgctgaa aaacgtgagg agtatgtgct atcggaggaa ggaattgagg ctgccagacg
    12541 tgcccgtaac caggtgttta ccgttgtgga ggtaatgccg gaattccctg gcggacaggg
    12601 tgctctgctg aaattcctgg cgacgaatgt cagatacccg gaatcggccg ttaaaaatgg
    12661 tatagaggga cgggttagct gttctttcgt tgttggaaaa gacggggcta tctcggaggc
    12721 agaagtgatt cgtggggtaa gtccggaact gaatgaggag gctttgcgtg tgataaactc
    12781 catgccggta tggtcgccgg ggaaacagcg gggcaaagtg gttaatgtca aatatacggt
    12841 accggtaact ttccggcttt ccggtggaaa gaaaaaaaca tcctctcgta tcgtgcagag
    12901 gcagattaaa gaagtcgata cgtccggtcg tgtctttacg gtagtgcaac agatgccgga
    12961 atttccgagt ggacaggctt cgttgttgaa atatctggca acacgcataa aatatccggc
    13021 tattgctcag gagaatggaa tacaaggacg tgtctcttgc tctttcgttg tcgacacgga
    13081 tggaagtttg aaaaatattg aagtgatccg tggaatcgat ccttcgctgg acagggaggc
    13141 tgtccggatg atccgggaaa tgccgaaatg gaatcctggc gtacaaaaca atatggctgt
    13201 agccgtaaaa tatacggttc cggttacttt ccgtttgcag taattgacca gaatcggtca
    13261 ttaatacgat accattatga aatgtaagtt ttctctatta ctgtttcttt gcgtactgtc
    13321 cctttgggga caggcgcaga gtcttaatct tcaggaattg gtcaataaaa aacaatttca
    13381 ggaagttgta gcacgtgcgg atagtcttac tcctgccgat tcagccgatt atgctacaat
    13441 gtcggcaatc gggcaggcgt atgagggact gttgcgctat aaggaggcct atcagtgttt
    13501 ttctcattgc ttgaagatgg atacgaacaa tgtggatgca ttgaacgccg ttgccaggaa
    13561 tgcgatcaat ttcggaagga tagcggaagc taaacaatgt tatcgtaaag tattgggaac
    13621 cgacagcatg aacttctatg ccaactatca gttggcgcgt ctctattatc agttgggaga
    13681 ttatggtcga gcgacggaac actatcatat acttgcttcc atcgaaggtg aaaatccttc
    13741 tatcctgacc gggctggctg attgccatat taaaagaggg accggtccta atacgatgat
    13801 cgctctttct ttgtatgccc gtgctttgga gctgaacccg gaaaatgtac gtgtggcatc
    13861 ttctctgata aatacgttat tgcggatggg ggacggacag ggagctttgc aggtgtgcga
    13921 taccgccttg ttctataatc cggataacag ccagatacgg cagagtaaag ggatggctct
    13981 ctatatgacg aaagattata agcaggctga ttcagtctat accggtctat tggccgatgg
    14041 cgattcttct tttttgaatc ttaaatatgc gggggcggcc cgctatatgt ccggtcatgc
    14101 acttgatggg gtcgagctgc tggagaaggc ctatgaaata gattcgacgg atgtggaaac
    14161 agtcatgttg tatggcgctt ccctgggaaa aacatacgac cgtaaacggg cttatgagct
    14221 tttcgatctg gcggaaacga atatgcagcc gaaaaaattc ctagttaata tgttgacgac
    14281 cttccgaggt gatgccttgg aaagggacgg ccgttggccc gaagcggaaa agctgtatta
    14341 tgccgcatgg aaggaagacc caacccagtt gcacttcctg tataagatca gtacacaata
    14401 ctgggatgtc gatccgggac tctttcagca ggaggaaaaa ttgcaaaaga cgattttcag
    14461 tagatacact tacctgacag cctatatgaa gacagacaag tcgcaaaagt atctttataa
    14521 ttaccgccct ttcttggaag cggtttgtga agatgccttt ttccggaatg ccgatgaagt
    14581 gacgatgttg gctcccgatg ggaagaagac gaagttggct gtcgctgatc tgcgtgcctt
    14641 ggtcgcccaa ctgccgcaga tgccggaaga tgaacgtttg aggcgcgaga agatgcagga
    14701 acatattaaa aaagccaggg aaaaagaaaa ggaattgcgt aaaagcggtg ctaaactcga
    14761 tacgctcgcc ctgagtaagg aagaaaaaga gaaagcacgg aaaatgttga aagacgccga
    14821 cttggaatag atagaatatc tgaacaatat aatcgatat
//
