LOCUS       c00158_gnlPro..        14465 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJLHHPMI_158.
ACCESSION   c00158_gnlPro..
VERSION     c00158_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:22:38
            Original ID  :: gnl|Prokka|CJLHHPMI_158
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14465
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14465
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1436:11637]"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1437..11637
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
     cand_cluster    1..14465
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /kind="single"
                     /product="NADH_dehydrogenase_I"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14465
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NADH_dehydrogenase_I"
                     /region_number="1"
                     /rules="(Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and
                     Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2
                     and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7,
                     Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3,
                     NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))"
                     /tool="gutsmash"
     CDS             82..1296
                     /locus_tag="ctg158_1"
                     /transl_table=11
                     /translation="MIFLSRTHVTNEKKEIALISIDNTERIDAMNRIRDFENFFLMISD
                     YAKVGYAKLNLLNRKGYAIKQWYKNLGEEEDIPLSEVVAVYSQMHPEDRKRFLDFYDGV
                     RDGKRRHFQGEMRIRRPGTKNEWNWVSSNVMVTNYKPEENEIEIIGINYDITELKETEA
                     ELIQARDKAEMMDRLKSAFLANMSHEIRTPLNAIVGFSDLLVETEELAERQEYIKIVRE
                     NNELLLQLISDILDLSKIEAGTFEFTNGDVDVNLLCEDIVRSMGMKAKEEVELVFDDHL
                     PVCHVISDRNRIHQVISNFVNNAMKFTSEGSIHVGYKLKDGELEFYVEDTGIGIEKEQL
                     PHIFERFVKLNSFVHGTGLGLSICQSIVEQLGGRIGVDSEKGKGSRFWFTIPGVIVTEE
                     MNCAR"
     CDS             complement(1437..2876)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_2"
                     /sec_met_domain="Proton_antipo_M (E-value: 5.6e-73,
                     bitscore: 235.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYSQFLNMREELSLIAVLLLLFLADLFMSPDAHKNSGKARLNTM
                     LPVILMAIHTAINLIPGTAADAFGGMYHYVPMHTVVKSILNVGTLIVFLMAHEWMKRED
                     TSFKQGEFYVLTLSTLFGMYLMISAGHFLMFFIGLETASIPMAALIAFDKYRHNSAEAG
                     AKYILTALFSSALLLFGLSMIYGSAGTLYFDDLPAHIDGNPLQIMAFIFFFTGMAFKLS
                     LVPFHLWTADVYEGAPSTVTAYLSVISKGSAAFVLLAVLIKVFAPMINDWQEVLYWVTI
                     ASITIANIFAVRQQKLKRLMAFSSISQAGYIMLGVIGGTAQGMTALVYYVLVYAAANLG
                     VFAVITIVALRSQKFTLEDYAGLYKTNPKIALLMTLSLFSLAGIPPFAGFFSKFFIFMA
                     AFDAGFHLLVFIALVNTVISLYYYLLIVKAMYITPSDNPIPTFRSDRCTKWGLALCTLG
                     IIGLGIASIVYQSIDKLSFGI"
     CDS             complement(2914..4398)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_3"
                     /sec_met_domain="Proton_antipo_M (E-value: 2.2e-68,
                     bitscore: 220.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSIFVLIPLLMLAGLWAARGIKAIRGVMVTGASALLIASVVL
                     TFLYLGERSAGNTAEMLFRADTLWYAPLHISYSVGVDGISVAMLLLSAVIVFTGTFASW
                     RLQPLTKEYFLWFTLLSMGVFGFFISVDLFTMFMFYEIALIPMYLLIGVWGSGRKEYAA
                     MKLTLMLMGGSAFLLIGILGIYFGSGATTMNLLEIAQLHNIPFAQQCIWFPLTFLGFGV
                     LGALFPFHTWSPDGHASAPTAVSMLHAGVLMKLGGYGCFRIAMYLMPEAANELSWIFLI
                     LTGISVVYGAFSACVQTDLKYINAYSSVSHCGLVLFAILMLNQTAATGAILQMLSHGLM
                     TALFFALIGMIYGRTHTRDVRELAGLMKIMPFLSVCYVIAGLANLGLPGLSGFIAEMTI
                     FVGSFQNNDVFHRTLTIIACSSIVITAVYILRLVGKILYGTCTNKHHLELTDATWDERV
                     AVICLIVCVAGLGMAPFWVSHMIGESVLPVVSQLIP"
     CDS             complement(4437..6368)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_4"
                     /sec_met_domain="Proton_antipo_N (E-value: 2.3e-25,
                     bitscore: 78.5, seeds: 433, tool: rule-based-clusters)"
                     /sec_met_domain="Proton_antipo_M (E-value: 1.9e-87,
                     bitscore: 283.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTILILLLPFFSFLILGIGGKWMSHRTAGTIGTLILGAVAVLS
                     YVTAIQYFSAPRLEDGTFATLMPYNFTWLPFTETLHFDLGILLDPISVMMLIVISTVSL
                     MVHIYSFGYMKGEVGFQRYYAFLSLFTMSMLGLVVATNIFQMYLFWELVGVSSYLLIGF
                     YYTKPAAIAASKKAFIVTRFADLGFLIGILIYGYYGGTFGFTPDTVSLISGGASMLPLA
                     LGLMFVGGAGKSAMFPLHIWLPDAMEGPTPVSALIHAATMVVAGVYLVARMFPLFITYA
                     PNTLHMVAWVGAFTAFYAASVACVQSDIKRVLAFSTISQIGFMMVALGVCTSMNPHEGG
                     LGYMASMFHLFTHAMFKALLFLGAGSIIHAVHSNEMSAMGGLRKYMPITHWTFLIACLA
                     IAGIPPFSGFFSKDEILAACFQYSPVMGWVMTVIAAMTAFYMFRLYYGIFWGSEPPRAG
                     SHSEHNTPHGNLEAAPCRPHESPLAMTFPLMFLAVVTCGAGFIPFGHFISSNGESYSIH
                     LDPSVAITSVVIAIISIAIATWMYKNAKQPVADSLAKRFKGLHKAAYNRFYIDDIYQFI
                     THKIIFRCISTPIAWFDRHVVDGFFDFLAWATNTTSDEIRGLQSGQVQQYAYVFLCGAL
                     ALILLLIL"
     CDS             complement(6560..6868)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_5"
                     /sec_met_domain="Oxidored_q2 (E-value: 3.1e-22, bitscore:
                     68.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHMEYYLVVSTIMMFAGIYGFFTRRNTLAILISVELMLNATDIN
                     FAVFNRFLFPGGMEGYFFALFSIAISAAETAIAIAIMINIYRNLRSIQVRNLDELKW"
     CDS             complement(6906..7418)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_6"
                     /sec_met_domain="Oxidored_q3 (E-value: 4.9e-38, bitscore:
                     120.0, seeds: 708, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSTLETVVFYFLAAFIIAMSIMTVTTQRIVRSATYLLFVLFGTA
                     GIYFLLGYTFLGSVQIMVYAGGIVVLYVFSILLTSGEGDRAEKAKRSKVLAGLFTMIAG
                     LAIILFITLKHDFMQTANLAPQEISIHAIGNALLSSDKYGYVLPFEAVSILLLACIIGG
                     IMIARKR"
     CDS             complement(7421..7909)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_7"
                     /sec_met_domain="Fer4_7 (E-value: 3.6e-13, bitscore: 39.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.1e-05, bitscore: 15.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYKDKKYTYLGGLVHGISTLATGMKTSIKVYFRKKVTEQYPENR
                     KELKMFDRFRGTLNMPHNENNEHRCVACGLCQMACPNDTIKVTSETVETEDGKKKKILA
                     TYEYDLGACMFCQLCVNACPHDAITFDQNFEHAVFDRTKLVLKLNHDGSKVIEKKKEV"
     CDS             complement(7922..8998)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: NADHdh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_8"
                     /sec_met_domain="NADHdh (E-value: 4.6e-123, bitscore:
                     400.1, seeds: 435, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDFSIVTNWIHELLLSIMPEGLAIFIECVAVGVCLVALYAILAI
                     ILIYMERKVCGFFQCRLGPNRVGKWGSIQVVCDVLKMLTKEIFMPKGADHFLYNLAPFM
                     VIIASFLTFACIPFNKGAAILDFNVGVFFLLAASSIGVVGILLAGWGSNNKFSLIGAMR
                     SGAQIISYELSVGMSIMTMVVLTGTMQFSEIVEGQANGWFIFKGHIPAVIAFIIYLIAG
                     NAECNRGPFDLPEAESELTAGYHTEYSGMGFGFFYLAEYLNLFIVASVAATIFLGGWMP
                     LHIVGLDGFNAVMDYIPGFIWFFAKAFFVVFLLMWIKWTFPRLRIDQILNLEWKYLVPI
                     SMVNLLLMACCVAFGFHF"
     CDS             complement(9019..10611)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_30kDa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_49kDa"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_9"
                     /sec_met_domain="Complex1_30kDa (E-value: 1.2e-36,
                     bitscore: 115.9, seeds: 586, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_49kDa (E-value: 9.3e-66,
                     bitscore: 211.5, seeds: 265, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQEIQFIAPAALHDEMLRLRNEKQMDFLESLTGMDWGVADEKDAP
                     EKLRGLGVVYHLESTITGERIALKTATTNRELPEIPSVSDIWKIADFYEREVFDFYGIT
                     FVGHPDMRRLYLRNDWIGYPMRKDNDPEKDNPLCMTNEETFDTTQEIELNPDGTIKNKE
                     TKLFGEEEYVVNIGPQHPATHGVMRFRVSLEGEIIRKIDANCGYIHRGIEKMNESLTYP
                     QTLALTDRLDYLGAHQNRHALCMCIEKAMGIEVSERVQYIRTIMDELQRIDSHLLFYSC
                     LAMDLGALTAFFYGFRDREKILDIFEETCGGRLIMNYNTIGGVQADLHPNFVKRVKEFI
                     PYMRGIIHEYHDIFTGNIIAQSRMKGVGVLSREDAISFGCTGGTGRASGWACDVRKRMP
                     YGVYDKVDFKEIVYTEGDCFARYLVRMDEIMESLNIIEQLIDNIPEGPYQEKMKPIIRV
                     PEGSYYAAVEGSRGEFGVFLESQGDKTPYRLHYRATGLPLVAAIDTICRGTKIADLIAI
                     GGTIDYVVPDIDR"
     CDS             complement(10694..11296)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q6"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_10"
                     /sec_met_domain="Oxidored_q6 (E-value: 1.2e-26, bitscore:
                     83.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITKKPKIKSIPYDEFIDNESLEKLVKELNAGGANVALGVLDDF
                     INWGRSNSLWPLTFATSCCGIEFMALGAARYDMARFGFEVARASPRQADMIMVCGTITN
                     KMAPVLKRLYDQMPDPKYVVAVGGCAVSGGPFKKSYHVVNGVDKILPVDVYIPGCPPRP
                     EAFYYGMMQLQRKVKIEKFFGGVNRKEKKPDYLRNEE"
     CDS             complement(11287..11637)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_11"
                     /sec_met_domain="Oxidored_q4 (E-value: 2.9e-38, bitscore:
                     120.0, seeds: 391, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFTFLVVVLLTALAFVGVVIALSRAISPRSYNLQKFEAYECGIP
                     TRGKSWMQFRVGYYLFAILFLMFDVETAFLFPWAVVMRDMGPQGLISVLFFFIILVLGL
                     AYAWRKGALEWK"
     CDS             complement(11756..12133)
                     /locus_tag="ctg158_12"
                     /transl_table=11
                     /translation="MKQSLKFGLLLVLALLIHCATNGAMEDMCKVSSPTYRQEKCYVSQ
                     DRPIQDALERLYNLYTTQTCDMSHTDVAHVPTDKSMFLLIAYFCDHYKHQSPPYPVSSH
                     SPTYYYDPISYYIYGLRKIVI"
     CDS             12394..13998
                     /locus_tag="ctg158_13"
                     /transl_table=11
                     /translation="MKRTLWFIFFLLNSLFYLYADSENDSLLKVLDKVISERLIYTQKK
                     EATIKELKKKKVGLNSLEDIYNLNKEIIHQYETFVCDSAEQYIHENIDIAKTIGNKEYL
                     LEEQLRLAFVYSLSGLFIQANDIFKSIKCADLPDHLKALYCWNRIRYYENLIKYTDDVR
                     FSNEYISEKEAYRDTVMSILFDQSDEYRKEKAVKLQDKGSTKEALLILTEIYDKQEPAS
                     HGYAMMAMGLARAYRLIGNYALEEKFLMLAAMTDTKLAVKENEALLTLAVNLYHKGDID
                     RAYNYIKVALDDAIFYNSRFKNTVIARIHPIIENTYLIRLEKQKQNLRFYIFLTSLFVV
                     ALAITLYFTYKQTKIVSRAKRHLKAMNEELVGLNKNLDEANLIKEKYVGYFMNQCAVYI
                     NKLDEYRKNVNRKIKTGQIDDLYKSSSRPFEKELEELYHNFDKAFLKLYPNFVEKFNSL
                     LKPEERYKLEKDQLNTELRIFALIRLGITDVGQIAVFLHYSVQTIYNYKSKVKRMSTLD
                     SNIFEEEVKKLGSLSQK"
     CDS             14191..14427
                     /locus_tag="ctg158_14"
                     /transl_table=11
                     /translation="MSFSELYLIYYPKLVRFAKEFVMSEEDAENITQDVFTDLWEKRES
                     MNHIENMNAYLFRLVRNKCLDGSSSNLVVLLLL"
ORIGIN
        1 ctaaagctca caaattgggc agttaaagag ttctgctgtc tgatacaaga ggataaattg
       61 aattgataga actcaccttt tatgattttc ttatcccgaa ctcacgttac taatgaaaaa
      121 aaagaaattg ccttaataag cattgacaat acggagcgta ttgatgcaat gaaccgtatt
      181 cgtgattttg agaatttctt cttgatgata tccgattatg caaaagtagg atatgctaaa
      241 ttgaatctct tgaaccgcaa aggttatgct ataaaacagt ggtataagaa tttaggtgag
      301 gaggaagata ttcctttgag tgaggtggta gcagtttata gccaaatgca tcccgaagac
      361 cgtaagcgtt tccttgattt ttatgatgga gtcagagacg gaaaaaggag gcatttccaa
      421 ggggagatgc gtattcgtcg tcccggaacg aagaacgaat ggaattgggt cagcagtaat
      481 gtaatggtca ccaattataa accggaagaa aatgaaatag aaatcatcgg tatcaattat
      541 gacattacag aattgaagga gactgaagcc gaattgattc aggcacgtga taaagcagag
      601 atgatggatc gtttgaaaag tgctttcctt gccaatatga gtcatgaaat ccgtacgccg
      661 ctgaatgcca ttgtcggttt ctccgatttg ctggtagaaa ctgaagagct ggcagaacgt
      721 caggagtata ttaagattgt acgtgagaat aatgaacttt tgttgcaatt aatttcagat
      781 atactcgatt tgtcaaagat tgaagcgggt acatttgagt ttactaacgg agatgtagat
      841 gtaaatctgt tatgtgagga tattgtccgc tctatgggga tgaaagcgaa agaagaggtg
      901 gaactggtgt ttgatgatca tcttccggtt tgtcatgtca ttagtgaccg taaccgtata
      961 catcaggtga tctctaactt tgttaacaat gcaatgaagt ttacctctga aggaagtatt
     1021 catgtggggt ataaactaaa agacggagaa ttggagtttt atgtcgaaga tacgggaatc
     1081 ggtattgaaa aagagcagtt gccacatatc tttgagcgtt ttgtgaagct taattctttt
     1141 gtacacggta caggattggg actttctatt tgtcagagca tcgttgaaca attaggtggg
     1201 cggattggcg ttgattctga aaaaggaaaa ggatcaaggt tttggtttac tattcccgga
     1261 gtgatcgtga cggaagagat gaactgtgcc cggtagagtg gtaataaggc aggtgaatat
     1321 cttccttcct cattaataaa agcggctttt atatagaaga aacagtcttg gttttgatgt
     1381 cgattgatac tgacatgaaa ccaagaccgt ttctttggtg aaaaggtgta gtccgtttaa
     1441 attccgaacg acagtttatc gatagattga tatacaatac ttgcaatacc cagtccgatg
     1501 atacccagcg tgcaaagtgc cagtccccat tttgtgcagc ggtcgctgcg gaaagtagga
     1561 attgggttgt cggaaggagt gatatacatt gcttttacaa tcaatagata gtaatacaac
     1621 gaaatcactg tatttaccaa tgcgatgaat accagcaagt ggaaacctgc atcgaaagca
     1681 gccatgaaga taaagaactt agagaagaat ccggcaaacg gagggatgcc tgccaatgag
     1741 aacagagaca gagtcatcaa gagagcgatt ttgggattcg ttttataaag tcctgcgtaa
     1801 tcttcgagcg tgaatttctg actgcgtaat gccacgatag tgataacggc aaatactccg
     1861 aggttggcgg cagcgtacac taatacataa tataccaatg ccgtcatgcc ttgtgctgtg
     1921 cctccgataa cgcctaacat aatatatccc gcttgcgaaa tactggagaa cgccatcaaa
     1981 cgtttcagtt tttgctgacg gacagcaaat atattggcaa tagtgataga agcgatggtt
     2041 acccaataaa gtacttcctg ccagtcatta atcattggag cgaatacttt gataaggacg
     2101 gccaataata caaatgctgc cgatcctttt gatataacac tcaaataagc ggtaactgta
     2161 ctcggagcgc cttcgtaaac gtctgctgtc cataagtgga atggaaccag tgataacttg
     2221 aatgccattc ctgtgaagaa gaatataaat gccatgatct gtaacggatt tccgtcgata
     2281 tgggcaggga ggtcatcgaa ataaagagtc ccggcagaac catagatcat ggacagacca
     2341 aacaacagca atgcactgga gaaaagagct gtcagaatgt atttggcacc tgcttcggca
     2401 gagttgtgac ggtatttatc gaaggcaatc aatgctgcca tcggaataga agctgtttca
     2461 agaccgatga agaacatcag gaaatgtccg gcggaaatca tgagatacat accaaacaag
     2521 gtagagagtg taagcacata gaattctcct tgtttgaatg aagtgtcttc tcttttcatc
     2581 cactcgtgcg ccatcaggaa aacaatcagt gtaccgacat tcaggatcga tttaacaaca
     2641 gtgtgcatcg gtacatagtg atacatacca ccgaatgcat cggcagcagt tcccggaatc
     2701 aagttgatag ccgtatggat agccatcaga ataacgggca acatggtgtt caggcgtgct
     2761 ttcccactat ttttgtgtgc atccggactc atgaagaggt cagctagaaa tagcagcagt
     2821 aagacagcta tgagcgacag ctcttctcgc atatttagaa attgtgaata atccatcttg
     2881 tttatttatg aattaagaat tatgatttat gagttagggg attagttgtg agacaaccgg
     2941 taatacgctt tcaccaatca tgtggctaac ccagaaagga gccataccta gtccggcaac
     3001 gcaaacgatg aggcagataa cggctacacg ttcgtcccaa gttgcgtcgg tcagttcgag
     3061 gtgatgtttg ttggtgcagg ttccgtatag aatcttacct accaggcgca ggatgtagac
     3121 tgcggtaatc acaatcgaag agcaggcgat gatggtcagt gtgcggtgaa atacgtcgtt
     3181 gttctggaaa gagccgacga agatggtcat ttcagcaatg aaaccgctta atcccggcag
     3241 accgaggttg gcaagaccgg caatcacata acatacacta aggaacggca taattttcat
     3301 taaaccggca agttcgcgaa cgtcacgtgt gtgtgtacgt ccatatatca taccgatcag
     3361 agcaaagaac aaggctgtca ttaatccgtg tgaaagcatt tgaaggattg ctcctgttgc
     3421 tgctgtctgg tttagcatca gaatggcgaa aagaaccagt ccgcagtgag atacggatga
     3481 ataagcattg atatatttca agtcggtctg tacgcaagcg gagaaggctc cgtagactac
     3541 agagatacct gtcagtatca ggaatatcca ggaaagttcg ttggctgctt ccggcatcag
     3601 atacatggcg atacggaaac atccgtaacc tcccagtttc atcaatactc cggcatgaag
     3661 catggatacg gcagtcgggg cagaagcgtg accgtcagga ctccatgtgt ggaacgggaa
     3721 aagggcgccc aatacaccga agccgaggaa agtcagcggg aaccagatgc attgctgtgc
     3781 aaaaggtatg ttgtgcaact gtgcaatttc gagaaggttc atggtggttg ctcccgagcc
     3841 gaaatagatt ccgagaatac cgatcaatag gaaagcggaa ccgcccatca acataagggt
     3901 cagtttcatg gctgcatatt ctttacgtcc tgatccccat acaccaatca gcaggtacat
     3961 cggtatcaac gcaatttcat agaacatgaa catggtgaac aaatcgacgg atataaagaa
     4021 tccgaatact cccatagaca acagggtgaa ccagaggaaa tattctttcg tcagcggttg
     4081 caggcgccag gaagcgaatg taccggtgaa tacgatgaca gcagacaata acaacatggc
     4141 taccgaaatt ccgtcaacac ctactgaata agatatgtga agcggggcat accaaagcgt
     4201 atctgcacgg aaaagcattt ctgccgtatt tccggcgcta cgctctccca gatacaggaa
     4261 tgtaagtacg acggaggcaa tcagaagtgc cgatgcgcca gtaaccataa ccccccggat
     4321 ggctttgatt cctcgtgctg cccaaagtcc ggccagcatc aataagggga taagtacgaa
     4381 tatggataag aaattcatct ttatgattta ctatttaaag atttactatt tactatttag
     4441 agaatcagca gtaggataag tgccaatgca ccgcaaagga acacatacgc atattgttgt
     4501 acctgaccgc tctgcaaacc acgaatctcg tcgcttgttg tattggtggc ccatgccagg
     4561 aagtcaaaga atccatccac tacatgacgg tcgaaccatg cgataggagt agagatgcag
     4621 cggaagataa tcttatgcgt aataaactgg tagatatcat caatatagaa gcgattatag
     4681 gctgccttgt gcagaccttt gaatcgtttt gccaacgaat cagcaacagg ctgtttggca
     4741 ttcttgtaca tccatgtagc gattgcaatc gaaataatcg caataacaac gctcgtaata
     4801 gctactgacg gatcgagatg gatagaataa gattcaccat tcgaactgat gaagtgtccg
     4861 aaaggaataa atcctgctcc acaagttaca actgccagga acatcagcgg gaaagtcata
     4921 gccaacggac tctcatgtgg gcggcaaggt gccgcttcca agtttccgtg cggcgtgtta
     4981 tgttccgaat gggaacctgc ccggggcggc tcgctccccc aaaaaatacc gtagtaaagg
     5041 cggaacatat agaaagctgt cattgcagcg atgactgtca tcacccatcc cattacaggg
     5101 ctgtattgga aacaagcagc cagaatttca tccttcgaga agaagcccga gaacggagga
     5161 ataccggcaa tagccagaca agcaatcagg aatgtccagt gagtgatcgg catatatttg
     5221 cgtaaacctc ccatagcgga catttcatta gaatgtacgg catggataat gctacctgca
     5281 ccgaggaaga gtaatgcctt aaacatggca tgtgtgaaaa ggtggaacat ggaagccatg
     5341 tagcccaaac ctccttcgtg cggattcatg gaagtacaaa cacccagagc taccatcatg
     5401 aagccaatct gtgaaatggt agagaaagcc agtacacgtt tgatgtctga ttgtacgcaa
     5461 gccacacttg ccgcgtagaa tgctgtaaat gcacctaccc aagcaaccat gtgcagcgta
     5521 ttcggtgcgt atgtaatgaa aagtgggaac atacgtgcca ccagatatac accggcaact
     5581 accatggtag ccgcatgaat caatgcgctg accggagtag gaccttccat tgcatccggc
     5641 aaccagatat gcaacgggaa catggcactt ttaccggcac caccgacaaa catcagtccg
     5701 agagccaacg gaagcataga agctccaccg cttatcaagg atactgtatc cggagtgaag
     5761 ccgaatgtac caccgtaata tccgtaaatc aggataccga tcaggaagcc caagtcagca
     5821 aagcgagtaa caataaacgc tttcttggaa gcagcaatgg cagccggttt tgtataataa
     5881 aaaccgatta gcaggtaaga acttaccccc accagctccc aaaaaaggta catctggaag
     5941 atgttggttg caacgaccaa tcccagcata gacatggtaa acagggatag gaaagcgtaa
     6001 tagcgttgaa aaccgacttc tcctttcatg taaccgaaag agtagatatg taccatcagt
     6061 gacactgtag agatgacgat caacatcatt accgatatag gatcgagcaa gatgcccaaa
     6121 tcgaagtgta aagtctctgt aaaaggaagc cacgtgaagt tgtaaggcat cagtgtggcg
     6181 aatgttccgt cttccagtcg tggagcggag aaatattgga tagctgtaac gtaggatagt
     6241 actgctactg ctcccagtat cagcgtaccg attgtacccg ctgtccggtg ggacatccat
     6301 ttacctccga ttcccaatat gagaaaggag aagaaaggaa gaaggagtat tagaattgtt
     6361 agttccatac agttttattt aattacttga gttattatta ttaatttttg gtcttatagc
     6421 tgataatcac tatactcgga ccttctgttt ggtttcccgg tgtgaaacta gttgttcctc
     6481 ggtgagaaac actttgtttc tcggtgtgaa acgaagtgtt tcaagggatg aaacaccttg
     6541 ttcctgggaa tgaaacaaat caccacttca actcgtccag gttgcgcacc tgaatgcttc
     6601 gaagattacg ataaatgtta atcatgatgg cgatagctat tgcagtttcc gcagccgaga
     6661 tggcgatgga aaagagtgca aagaaataac cctccattcc ccccggaaaa aggaatcgat
     6721 tgaacacggc gaagttgatg tccgtagcat tcagcattaa ctctacagaa atcaggatag
     6781 ccagtgtatt tcggcgggta aagaatccat agattcctgc aaacatcatg atggtagaaa
     6841 ctaccaggta atattccatg tgtatcatat tcgaactcta ttttgatagt taatacttaa
     6901 aattcctatc tcttacgtgc aatcatgatg ccaccgatga tacacgccag caataatatg
     6961 ctgacggctt cgaaaggcaa tacataaccg tatttgtcac tacttaataa agcgttcccg
     7021 atagcatgaa tgctaatttc ttgcggggcc aaattagctg tctgcatgaa atcgtgcttc
     7081 agtgtgataa aaaggataat ggctaaaccg gcaatcatag tgaagagtcc ggctaagact
     7141 ttacttcgtt ttgctttctc ggcccggtcg ccttctccac tggtcagcag gatggagaat
     7201 acataaagaa cgacgatacc accggcataa accataatct gaacggaccc cagaaaggtg
     7261 taacccagca aaaaatagat gccggccgtg ccgaagagca cgaagagcag gtaggtggcc
     7321 gagcgtacga tacgttgggt agtcaccgtc atgatggaca tagcaataat aaatgctgcc
     7381 aaaaagtaga atactactgt ttcaagtgtt gatcccatat ctaaacttct tttttctttt
     7441 ctattacttt actaccgtcg tggttcaact tcaggacaag tttcgtccgg tcgaagactg
     7501 catgttcgaa gttctgatcg aacgtgatgg catcgtgcgg acaagcattg acacagagct
     7561 ggcagaacat acaggcaccc aaatcatatt cataggttgc caggattttc ttcttctttc
     7621 catcttctgt ttcgacggtt tcgctggtca ctttgattgt atcgttcgga caggccattt
     7681 gacacagtcc gcaagctaca cagcgatgtt cattattctc attgtggggc atattcagcg
     7741 taccacggaa acggtcgaac attttcagct ctttccggtt ttcggggtat tgttcggtca
     7801 ctttcttacg gaagtatacc ttgatgctgg ttttcatacc cgttgccagt gtactgatgc
     7861 catgcaccag accacctaag tacgtatatt ttttatcttt atattccata attttcattt
     7921 atcaaaagtg gaagccgaaa gctacgcagc atgccattaa taatagattt accatagaaa
     7981 ttggaaccag gtatttccat tccagattca agatctggtc gatacgcaag cgtgggaaag
     8041 tccatttgat ccacatcaga aggaatacca caaagaatgc tttggcgaag aaccagataa
     8101 agcccggaat ataatccatt acagcattaa atccatccaa accaacaatg tgcagcggca
     8161 tccatcctcc caggaagatg gtggcggcaa cactggctac gataaacaga ttcaagtatt
     8221 ctgccagata gaagaaaccg aaacccatac cggagtattc tgtatgatat ccggctgtca
     8281 gctcactttc cgcttcggga aggtcgaacg ggccacggtt acattctgca tttccggcaa
     8341 tcagatagat gatgaaagca atgaccgcag gaatatgtcc cttgaagatg aaccaaccat
     8401 tagcttgtcc ttctacgatt tcagaaaatt gcatggttcc cgtcagcact accattgtca
     8461 tgatactcat accaaccgaa agttcataac tgataatctg tgcaccgctt cgcatggcac
     8521 cgatcaaaga gaatttgttg ttactacccc aaccggccag caagataccg acaactccaa
     8581 tgctggaagc tgccaacagg aagaacacgc ccacattaaa gtccagaatc gccgcacctt
     8641 tattaaaagg aatacaagcg aaagtcagga atgaagcgat aatcaccatg aatggagcaa
     8701 gattgtaaag gaaatggtcg gcacccttcg gcatgaagat ttctttggtc agcattttga
     8761 gcacgtcgca gaccacttgg atagaacccc atttaccaac acggttcgga ccaagacgac
     8821 actggaagaa accgcaaacc ttacgctcca tgtagatcaa tatgatagcc aggatggcat
     8881 acagtgctac gaggcacacg ccgacagcta cacattctat aaagatggct aatccctccg
     8941 gcataatgga gagcagtagc tcatgtatcc agtttgttac tatactaaag tcgaacatat
     9001 atttttaata attaagtatt atctgtcaat atccggaacg acataatcta ttgttccgcc
     9061 aatagcaatt aagtcggcaa tctttgtgcc ccgacaaatg gtgtcaattg cagcaacaag
     9121 cggcaagccc gtagcacggt agtgcaggcg gtaaggcgtt ttgtcaccct gactttccag
     9181 gaagacacca aattcaccac gacttccttc tactgctgca tagtaactgc cttccggaac
     9241 acggatgata ggtttcatct tctcctgata aggtccctcg ggaatattgt ctattaattg
     9301 ctcaatgatg ttcagacttt ccatgatctc atccatacgc accaggtaac gggcaaagca
     9361 gtcaccttcc gtataaacga tttctttgaa atcgactttg tcatatacac cgtatggcat
     9421 tcgtttacgt acgtcacacg cccatcctga tgcacggcct gtacctccgg tacaaccgaa
     9481 agagatggca tcttcacggc ttaacacacc gacgcctttc atacggcttt gtgcgatgat
     9541 gttacccgtg aatatatcat gatattcgtg gatgattcct ctcatatatg gaatgaactc
     9601 ttttactcgt ttgacgaagt taggatgaag atcagcctgt acaccgccaa tcgtattgta
     9661 gttcataatc agacgtccgc cgcaagtttc ttcaaaaata tcgagaatct tctcgcggtc
     9721 acggaatcca taaaagaatg ctgtcaatgc tcctaggtcc attgcaagac aagagtaaaa
     9781 cagcaagtga gaatcgatac gttgcaactc gtccattatg gtacggatgt actgtacgcg
     9841 ttcactgacc tcaatgccca tggctttttc aatgcacata cacaatgcat ggcggttctg
     9901 atgcgcgccc aaatagtcca gacggtctgt caaagccaat gtttgagggt aagtgaggct
     9961 ttcattcatt ttctcgatgc ctcggtggat atacccgcag ttcgcatcaa tcttacgaat
    10021 aatttcacct tccagagaaa cacggaagcg cattacacca tgagtagcag ggtgttgcgg
    10081 accgatgttg actacatatt cttcttcgcc gaacagtttc gtctctttgt tcttgatggt
    10141 tccgtccggg ttcagttcta tttcttgagt cgtatcaaac gtctcttcat tagtcatgca
    10201 cagtgggtta tccttttccg ggtcgttatc tttacgcatc ggataaccga tccaatcgtt
    10261 gcgcaggtag agccggcgca tatcaggatg accgacaaag gtgatgccat aaaaatcaaa
    10321 aacttcacgt tcgtagaagt cggctatctt ccagatgtcg ctgacagacg gaatttccgg
    10381 tagctcgcgg ttggttgtcg ctgtttttag tgctatccgt tcgcctgtaa tggtagattc
    10441 cagatggtag actacgccta agccgcggag tttttccgga gcgtctttct catcggctac
    10501 tccccagtcc ataccggtga ggctttcgag aaagtccatc tgtttttcat ttcgcaagcg
    10561 cagcatctcg tcgtgtaacg ctgcaggagc tataaattgt atttcttgca taaatcaaat
    10621 taaattaaga atgaaaaatt aagaatgaaa aatctgccgg gatgttgcat gcgaattctt
    10681 cattcatcat tcatcattct tcatttctta aataatccgg tttcttctct tttctgttta
    10741 ctccaccaaa gaacttttct attttcactt tgcgttgcaa ttgcatcatg ccataataga
    10801 atgcttcagg acgtggcggg catccgggaa tatatacatc taccggaaga atcttgtcca
    10861 ccccgtttac tacgtgatag gacttcttga aaggacctcc gctgacagcg catccgccta
    10921 cggcaaccac atacttcgga tcgggcatct ggtcgtaaag tcgtttcagt accggagcca
    10981 ttttattggt gattgttccg cataccataa tcatatcagc ctgacgcggg ctggcacgtg
    11041 ctacctcaaa cccaaagcgg gccatgtcat aacgcgcggc acccagtgcc ataaattcga
    11101 taccacaaca actggttgca aaggtaagcg gccacagtga attgctgcgc ccccagttga
    11161 taaagtcgtc aagtactccg agggcaacat tggctcctcc agcattaagt tctttgacca
    11221 acttttccaa tgattcattg tcgataaact catcatacgg aatagatttt atttttggct
    11281 ttttggttat ttccattcca aagctccttt cctccaggca taagcaagac ccagaactaa
    11341 aatgataaag aagaagagaa cactaataag tccctgtggt cccatgtcac gcataactac
    11401 cgcccacgga aacagaaaag ctgtttcgac atcgaacata aggaatagga tggcaaacaa
    11461 gtagtagcct acacggaact gcatccatga tttaccacgt gtcggtatac cacattcata
    11521 agcctcaaac ttttgcaggt tgtatgaacg gggagagata gcacgcgaga gggctattac
    11581 tacaccgaca aaagcaagcg ctgtcagtaa aacaacaact aaaaatgtaa aattcataat
    11641 tcaatagctg tttagattga atattatata gaaataagca attagtctat tcgccctatg
    11701 gagaataaaa ccaactgtaa taaatgacga gcaaaagagt ctactgtact gtaggctaaa
    11761 tgacaatctt tctcaaccca tatatataat aggagatagg atcgtaataa tatgtaggag
    11821 aatgggatga gacagggtaa ggtggacttt gatgtttgta atggtcacag aaataagcga
    11881 ttaacaaaaa catgctttta tctgtcggaa catgtgcgac gtctgtatga ctcatgtcac
    11941 aggtttgagt cgtataaaga ttataaaggc gttccaaagc atcctgaatc ggacgatctt
    12001 gtgatacata gcatttctcc tgccgataag tcggggagga aactttgcac atatcttcca
    12061 ttgctccgtt agttgcacaa tggatgagca aagccaacac taaaagtagt ccgaatttta
    12121 agctttgttt catctttctc ctttaacggc tgcaaatata gaactaatat ttatactttt
    12181 tgcaaagtcc gtatagcaaa aaagcttttt ttaactccat atcttttaga ttcatttttt
    12241 agtcagcatg gtttcacaaa tatcatttag aatgggggaa tttctccatc ttcatttgtt
    12301 aaaagatgca ataaaaagaa tgatttacgc tctttttggc gaataacaca aagaaaatac
    12361 atttttttgc agattaagaa agaatacatg attatgaaac gcacactttg gtttatattt
    12421 ttccttctaa actctttgtt ttacctctat gcagatagtg agaatgattc tttgttgaag
    12481 gtgttagaca aagtgatttc tgaacgtttg atatataccc agaaaaaaga agctaccata
    12541 aaagaattaa agaaaaagaa agttggcctt aattcgttgg aggatatata caatttaaat
    12601 aaagagatta tccatcaata tgagactttt gtctgtgact cggcagaaca atatattcat
    12661 gagaatattg atatagcaaa aacgattggt aataaagaat atcttttgga agagcagctc
    12721 cggttggctt ttgtctattc tttatccggt ttgtttattc aagcaaatga tatttttaag
    12781 tcgataaaat gtgcggattt acccgatcat ttgaaagctt tgtattgctg gaatcgtata
    12841 cgttattatg aaaatctcat taaatacacg gacgatgtac ggttttcaaa cgagtatata
    12901 tcggaaaaag aggcttatcg ggatactgtg atgagcatct tatttgacca gtcggatgaa
    12961 tatagaaaag aaaaagctgt gaagcttcaa gataagggaa gtaccaaaga ggctcttctg
    13021 attttgacag agatatatga taaacaagag ccggcatctc atggatatgc tatgatggct
    13081 atggggcttg ccagagctta tcggttgatt gggaattatg cactggaaga aaagtttcta
    13141 atgctggctg ctatgacaga tacaaaactg gctgtcaaag agaatgaggc attattgaca
    13201 ttggcagtta atttgtatca taaaggagat atagacaggg cttataatta tattaaagta
    13261 gcattggacg atgccatctt ttataattcc cgctttaaga atacggtaat tgcccgcatc
    13321 catccgatta tagaaaatac atacttgatc cggttggaaa aacaaaagca gaaccttcgt
    13381 ttctatatat ttctgactag cttgtttgtg gtagctcttg ctatcaccct gtattttaca
    13441 tataaacaaa caaaaattgt atcccgggct aaacggcatc ttaaagctat gaatgaggaa
    13501 ctggtcgggc tgaataagaa tctcgacgaa gctaatctga ttaaggaaaa gtatgtgggg
    13561 tatttcatga atcaatgtgc cgtttatatt aataaactcg atgagtacag gaagaatgtg
    13621 aacaggaaaa tcaagaccgg acagattgat gatttatata agtcatcctc ccgacctttt
    13681 gaaaaggaac ttgaagaact atatcataac tttgataaag cgttccttaa attgtatcct
    13741 aactttgtgg aaaagttcaa ttctttgttg aaaccggagg agcgttataa actggaaaag
    13801 gaccaactga atacagaatt acgcatattt gcattgatac ggttaggaat taccgatgtt
    13861 ggacagattg ctgtattttt gcattattct gtgcagacaa tctataatta taagagtaaa
    13921 gtgaagagaa tgtccactct tgatagtaat atctttgagg aggaggtaaa aaagcttggt
    13981 tctttgtctc aaaaatgatt ctatccggtt taccaaaact aaaaaatggt cttgttataa
    14041 actgttgatt attaaatgta tatataataa ttgatctata aaacgtttac tttcccgcct
    14101 acttccacta agaagtaggc ttttttcatc tctatatttg catcacaaga tttttgataa
    14161 ctgaatacta atctaaagaa acacacaact atgagttttt cagaattgta tcttatttat
    14221 tatcccaaac tagttcggtt tgcaaaagaa tttgtgatgt cggaagagga tgctgagaac
    14281 ataacgcaag acgtgtttac agacttatgg gaaaagagag agtcaatgaa tcatattgag
    14341 aatatgaatg cttatctttt cagacttgtg agaaacaaat gtttggatgg ttcttcgtca
    14401 aatttggtgg tacttcttct attgtgaata aataatcttc gctctcagta gtttaattcc
    14461 tgccc
//
