LOCUS       c00099_gnlPro..        13057 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GFOGEDAG_99.
ACCESSION   c00099_gnlPro..
VERSION     c00099_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:38:46
            Original ID  :: gnl|Prokka|GFOGEDAG_99
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13057
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13057
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[84:3057]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      85..3057
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13057
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13057
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             2..73
                     /locus_tag="ctg99_1"
                     /transl_table=11
                     /translation="IYADHMKKRCNFVRSKEKDNYNL"
     CDS             85..2313
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_2"
                     /sec_met_domain="Gly_radical (E-value: 2.8e-46, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2329..3057
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_3"
                     /sec_met_domain="Radical_SAM (E-value: 2.5e-29, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(3102..3527)
                     /locus_tag="ctg99_4"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRADRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDEDGKAADTRTSCQKESLHRLVRELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWGGSKSVPVSR"
     CDS             complement(3702..4205)
                     /locus_tag="ctg99_5"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             4399..4629
                     /locus_tag="ctg99_6"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             4717..6834
                     /locus_tag="ctg99_7"
                     /transl_table=11
                     /translation="MEHFTIFQDFYRVIAEMTEEEIVSAISNGTYRETVEDVRRIFAEQ
                     GEKAANEKKIELPEITFSANYRGGRSNATLVKYLGYIVVDIDHQTQEALARILALAKKC
                     AHTRIAFISPKGMGLKIVVRVCRTDGTLPETIQEIEDFHHAAYHKIASFYAQLCGVEVD
                     TSGQDVSRTCLFSYDPDIYFNPDATAVIVEQPPMFFKSQKKKRASGKKKKTTAPDNNPL
                     TEQVALNYHSSHASLMVTLNYYHNKSEKYVTGNRNNYLHCLACMYNRYGVPQEEAAAFI
                     KSQFTDLPADEMDALIGSAYGHNEEFDTRKLNSTQKRILQIEQHIKENYDTRYNEVLHI
                     MEYRRRKTDTEQPEPFHILDEMMENSIWMEMNELGYSCTVKTIQNLIYSDFSITYHPIR
                     EYLDSLPEWDGTDYIGILANSVHTSHQKFWVECLERYLVGMCAAATQDDVVNHTVLLLC
                     SEIQNIGKTTFINNLLPPELRAYLSTGLINPSNKDDLAKIAQAMLINLDEFEGMSGREL
                     NIFKDLVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVDSME
                     FIKINYAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPE
                     RFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIID
                     TEQVKSNRLYE"
     CDS             complement(7078..7443)
                     /locus_tag="ctg99_8"
                     /transl_table=11
                     /translation="MTKIENQTQYEWAVKRVEDLLPLVKDDTPLNDPNSIELELLSNLV
                     ADYSEEHFSLGEPSLVDVLKLRMYEMGLNQKSLSQLIGVSPSRLSDYISGKCEPTLKVA
                     REISKKLNIDASIVLGV"
     CDS             complement(7448..7741)
                     /locus_tag="ctg99_9"
                     /transl_table=11
                     /translation="MRIFTEQALKEYAEEHPDSKVALQEWVTIVKKSEWACFADIKKTF
                     NSADSVGNQHYVFNVKGNNYRLVVVVKFTVKFVYIRFIGTHKEYDKIDCANI"
     CDS             complement(7839..8141)
                     /locus_tag="ctg99_10"
                     /transl_table=11
                     /translation="MQINNHQIVDYDAVLDAKFGAEGTPERAEAEEKAYAFYTGQIIED
                     ARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCRIEFSMSL"
     CDS             complement(8263..8487)
                     /locus_tag="ctg99_11"
                     /transl_table=11
                     /translation="LNNNSYICSMEKKRKIRTYGGYFEAFMETLTEKEQDKIQYGLLLL
                     KTQERLSTKFVKFVQDGVFELRTEYNGNI"
     CDS             complement(8517..8762)
                     /locus_tag="ctg99_12"
                     /transl_table=11
                     /translation="MSHLTPVIIEYRGNPKQYVSVVLDAINLGRLTYDGVANCEQTFRA
                     LASVVDVISPKNGKTLSVETLVSYEKKKRAGEFEEK"
     CDS             complement(8771..8905)
                     /locus_tag="ctg99_13"
                     /transl_table=11
                     /translation="MENSLNDELLCSLKDELREVTAQINVHSEKLMDLLDQKKESSVN"
     CDS             complement(9032..10387)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 152.3; E-value: 5.6e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg99_14"
                     /sec_met_domain="MFS_1 (E-value: 6e-47, bitscore: 152.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKQLINFYKVSSPRPCNGETLSSSDARRLKFLKWSTFLSATFGY
                     GMYYVCRLSLNVVKKPIVDEGIFSETELGIIGSVLFFTYAIGKFTNGFLADRSNINRFM
                     TTGLLVTALVNLCLGFTNSFILFAILWGISGWFQSMGAASCVVGLSRWFTDKERGSYYG
                     FWSASHNIGEALTFLIIASIVSVLGWRYGFFGAGIVGLIGALIVWKFFHDTPESMGFPS
                     VNVPKQKKEMSETETADFNKAQRQVLLMPAIWILALSSAFMYISRYAINSWGVFYLEAQ
                     KGYSTLDASFIISICPVCGIIGTMFSGVISDKLFGGRRNVPALIFGLMNVFALCLFLLV
                     PGAHFGIDVLAMVLFGLGIGVLICFLGGLMAVDIAPRNASGAALGVVGIASYIGAGLQD
                     VMSGILIEGQKTVQNGVDVYDFTYINWFWIGAALLSVLFALLVWNAKSKEMD"
     CDS             complement(10401..11294)
                     /locus_tag="ctg99_15"
                     /transl_table=11
                     /translation="MRKLFIFSLLLIAISGINAQNRKLRANLLDKNNHSVMVVSHRGDW
                     RNAPENSLQAIQNCIDMGVDMVEVDLKKTKDGHLIVMHDQTIDRTTTGKGKPENYTLEE
                     LRRFRLKNGAAHKTTHLIPTLEEVMLLCKGKILVNIDKGYDYFKEAYCILEKTGTVDQC
                     VIKAGLPYEQVKVENGEVLDKVIFMPVINLNKEDAEKIIDSYQKHLKPIAYELVFDNDE
                     KETLRLIQKVRDSGARLFVNSLWPKLCGGHDDDRAVEFHQPDESWGWIIAQGAKLIQTD
                     RPALLLEYLRNKKLHD"
     CDS             complement(11310..11987)
                     /locus_tag="ctg99_16"
                     /transl_table=11
                     /translation="MELVIEAIHDFPKDIDANEALKRITEKIHSFYVQHRLLEELEKTP
                     GSRFTANGVIYSYEKNEIWQIGDCQCLFGNTYSSNEKEIDAIMANARAVVNEIALLNGA
                     TPDDLLSNDPGRNFIYRFLQQQAILQNNPDKNQPYSFPVFDGFPINMHQVRIFSIGNHT
                     QIVLSSDGYPCLFPTLRESECYLMNILENDPLCMRQYKSTKGIKKGNCSFDDRAYLKIR
                     INR"
ORIGIN
        1 tatttatgct gatcatatga aaaaacgttg taactttgtg cgctctaaag aaaaggataa
       61 ctacaacctc taattttatc atttatggaa ttaaataaga tctttaaaga cggtctttgg
      121 agcacagaaa tcaacgtaag agatttcgtt agtcacaaca tcactccgta ttatggagat
      181 gcttctttcc tcgaaggacc taccgaacgc acaaaagctg tatggaaccg ctgcctcgaa
      241 gcactggcag aagaaagagc caataacggc gtacgctcac tggataatgt caccgtctca
      301 accatcactt ctcataaagc cggatatatc gacaaagaaa atgaactgat cgtcggtctg
      361 cagacagacg aacttctgaa acgtgccatc aagcctttcg gaggtatcaa cgtagtgagc
      421 aaagcctgcc acgaaaacgg cgtggaagtg gacgaccgtg taaaagatat attcactcac
      481 taccgcaaga cgcacaacga cggagtattt gacgtatata ccgaagaaat ccgttcgttc
      541 cgttctctgg gattcctcac cggacttcct gacaactatg cccgtggacg tatcatcggc
      601 gactaccgcc gtatggctct ctatggtatc gaccgactga ttgaggcaaa aaaagaagac
      661 ttgcgtaacc ttaccggtcc gatgaccgaa gcccgcatcc gcctgcgcga agaagtggca
      721 gagcaaatca aggcattgaa agacatgaaa gtaatgggcg aatactacgg actcgacttg
      781 agccgtcctg cctacaccgc acaagaagca gtacaatggg tatacatggc ttaccttgct
      841 gccgtaaaag aacaagacgg tgctgctatg tcactaggta acgtctcttc gttcctcgac
      901 atttatatgg aatatgaatt gagcaaagga accatcacag aatctttcgc acaggagctg
      961 atcgaccagt ttgtcatcaa actgcgtatg gtgcgtcacc tgcgtatgca atcttacaac
     1021 gacatcttcg ccggcgaccc gacatgggta accgaatccc tgggtggacg cctcaacgac
     1081 ggacgtacca aggtgacaaa gacttctttc cgctttctgc aaacactcta caacctcggc
     1141 ccttcaccgg aaccgaacct gactgtattg tggagcccgg aactgccgga aggattcaaa
     1201 gaattctgcg caaaagtatc tatcgacact tcttccatcc aatatgaaaa cgacgacctg
     1261 atgcgtgaag tgcgccagtc tgacgattac ggaatcgcat gctgcgtatc ttatcaggaa
     1321 atcggaaaac aaatccaatt cttcggcgca cgttgcaacc tggcaaaagc cctgttgctt
     1381 gccatcaacg gcggacgttg cgaaaacacc ggtacggtaa tggtgaaaaa tatccccgta
     1441 ctaaccagcg acacactgaa cttcgaagaa gtaatgagca actacaagaa ggtattgaca
     1501 gaaatcgccc gtgtttacaa cgaagcgatg aacatcatcc attatatgca tgataagtat
     1561 tactacgaaa aagcccaaat ggctcttgta gataccaacc cacgcatcaa ccttgcttat
     1621 ggtgtagccg gactttctat cgccctcgat tcactgtcgg ccatcaaata tgccaaagtg
     1681 accgcacgcc gcaacgacat cggtctgaca gaaggtttcg atattcaagg cgaattccct
     1741 tgcttcggta atgacaacga caaggtagac cacctgggtg ttgacctggt ctatttcttc
     1801 agcgaagaat tgaagaaact tccggtttac aaaaatgccc gtcctacttt atctttgctc
     1861 accatcactt ccaacgtgat gtatggcaag aagacaggtg ctactcccga cggacgcgcc
     1921 aaaggtgtcg cttttgctcc gggagccaac cctatgcacg gacgtgacaa gaacggtgcc
     1981 atcgcctctt tgagttccgt agcgaaatta cgttaccgcg actcacagga cggtatcagc
     2041 aacactttct ccatcgtccc caaatcactg ggagctactg aagaggatcg cgtagaaaat
     2101 ctggtgacaa tgatggatgg ctatttcacc aaaggcgctc accacctgaa cgtgaacgta
     2161 ctgaaccgtg aaatgcttta cgatgccatg gaacatccgg aaaaatatcc gcaactcacc
     2221 atccgtgttt ccggttatgc cgtaaacttc gtgaagttga gccgcgaaca tcaattggaa
     2281 gttatcagcc gtagcttcca cgaacgtatg taatcagatc tactcaatat gacgataaac
     2341 gtacattcat acgaaagtat gggaacattc gacgggccgg gcttacggct cgtcgttttt
     2401 cttcaaggat gcaatttccg ctgcctgtat tgtgccaacc ccgacacgat agccggaaaa
     2461 ggaggcacac ctaccccacc ggaagaaatc gtccgcatgg ctatgagcca acgtcctttt
     2521 ttcgggaaac gcggaggagt cactttctcc ggaggagaac ctacgtttca ggccaaagca
     2581 ctagtccctt tagtgcgtga actgaaagaa aagggaatac atgtatgcat agacagcaac
     2641 ggcggtatct ggaacgaaga agtagaagaa cttttcaaac tgacggatct tgtattgctg
     2701 gatattaaag agttcaatcc ggcacgccat caagcactga ccggaagaag taacgagcaa
     2761 accatccgca cggcagcatg gctggaagaa aacgagaaac ctttctggct gcgttatgta
     2821 ttagtgcccg gatacagcga tttcgaagag gatatccgcc gcttgggaga ggctctggga
     2881 aaatataaga tggtgcaacg agtggaaatc ctgccttatc atacattagg cgtacataag
     2941 tatgaagcga tggagcagga atacaagctg aaagacgtaa aagaaaatac ccccgaacaa
     3001 cttgaaaaag ccgcggaggt atttaaagag tatttcacta ctgtggtggt caattaacca
     3061 ccacagtaat aaataggata aaaatcacca tgtctctgct ttcacctcga aacagggaca
     3121 ctctttgatc cgccccaagg gtcaacaatt ccattataat tggtgtcagg actcaagtcc
     3181 cgatgaccga ccacctttgc atccggataa cgctgcaaca gttcgcgcac caggcgatgc
     3241 aaagattctt tctggcagga agtacgtgta tccgctgcct ttccgtcctc atccagtccg
     3301 ccttcatagc acacccctaa actaatcgca ttaaaaccgc gtgcatgagc acccaccgta
     3361 tcttcatccc tcatcggttc tatctgtccc gacttgcgga tataataatg atacccccaa
     3421 caagaaaagc cccgaaagcg atgggcagtg tccacatcct tcgccgtgaa gtcgcgatca
     3481 gcacgggtag cagagcagtg aatcacaatc agactaatct ttctcatcgt ccttctccct
     3541 ttccgttgtt ttcacattac acacttcctt atgggtagca ttgaagcgca cctctctcac
     3601 aattctgttc cgctttcttt ttccgaagaa aggcacaagg aacatgatta catccaaaat
     3661 cttagttaca atttctttca tttgatctaa tattaaagtt atcatgctgc cggatccgga
     3721 gcttctccgc ttccaccacc gtctgaaccg ccaccggaac ctttgtcatc gtcttctcct
     3781 tcattgccgc taccgcccgt ttgggccacc gcacgcgtcg ttacttgctg gtagctaaga
     3841 atcttcgtga tgtccgccaa cgtctttccg ggacggaaaa taatatgggc agccgtaatc
     3901 agcgaacttg aaaactcctt gaccgacaca gctccttcac tgttcaaccc gatctgcaaa
     3961 ctgcccaaat cacccagccg gactattctt cccgctttca acgcacgctt cgcctcataa
     4021 agaatacccg aaatggcggc acgcacatct gtctccgtac aggtagaccg actggtgatt
     4081 ccctcgcaca actcttcaaa atccaactct cccgaagcct gtgcctgcgc gtaatacttt
     4141 gccgactcat cctttttggc aggattcttg cgcggcacta ctgaataagt tactgtcatt
     4201 gccataataa aataatttta aattttcata catttcgaac gcgttcctta tttgttaacg
     4261 acataaagat aacacatttt tcaccctccg gattccccaa cgaagtttcc tgatattcta
     4321 tgaataataa tgacgttatt cttttaataa accattaatt ttcagtaact ttatagcata
     4381 aaccaaacat cattcatcat gtattatccg gatcagccgt ttcatatccg cacttataaa
     4441 aagtcggaac tagctcatct ttacaacccc aacgtatgcc tcaaagtagc cttacaaata
     4501 ctacgtcgtt ggattgtcta caaccttccg ctcctgcaag aactcgaaca agaaggctat
     4561 cgtgcccgca accgccttct ctctccccgg caagtggcaa cgatcatacg ctatttggga
     4621 gaaccctagg aacttaatca aaaaaacgaa aagttccatt ctattatttt acaaacaaat
     4681 ttctttgcaa ccgcaaatta aaaagaacaa accaacatgg agcattttac catctttcaa
     4741 gacttttacc gcgtcatagc cgaaatgaca gaagaagaaa tcgtatcggc catcagcaac
     4801 ggcacatacc gggaaacggt ggaggacgtg cgccgaatct tcgcggaaca aggcgagaaa
     4861 gcagccaacg aaaagaaaat agaactaccg gaaatcacct tttcagccaa ctaccgggga
     4921 ggacgttcaa acgcaactct cgtcaagtat ctgggataca tcgtggtaga catcgaccat
     4981 cagacacagg aagcattggc acgcatcctc gcactggcaa aaaagtgtgc ccacacccgc
     5041 atcgctttca tcagccccaa aggaatggga ctgaaaatcg tggtacgtgt atgccggaca
     5101 gacgggacat tgcccgaaac aattcaggaa attgaagatt tccatcatgc tgcttatcac
     5161 aaaatcgctt ccttttatgc ccagctctgc ggagttgagg tcgacacttc cgggcaggat
     5221 gttagccgca cttgcctgtt ctcttacgat ccggatattt atttcaatcc cgatgccaca
     5281 gctgtcatcg tggaacagcc accgatgttc ttcaagtctc aaaagaagaa aagggcatcc
     5341 ggcaaaaaga aaaagacgac agcaccagac aacaatcccc tcaccgaaca agtggccctc
     5401 aactaccatt cctcgcacgc ttccttaatg gtgactctga actattatca caataaatcc
     5461 gaaaagtacg tcaccggcaa ccggaacaac tacctgcatt gcctggcttg tatgtacaat
     5521 cgctacggcg tcccccagga agaggcggca gcttttatca agagccagtt caccgatctt
     5581 cccgcggatg aaatggacgc actgatcggg agtgcttacg gacacaatga ggaattcgac
     5641 acccgcaagc tgaatagtac gcagaagcga atattacaga ttgagcaaca tatcaaagaa
     5701 aattacgata cacgctacaa cgaagtgctt catatcatgg aatatcgcag aaggaaaacg
     5761 gacacggagc aaccggaacc tttccatatt ctcgacgaaa tgatggaaaa cagcatttgg
     5821 atggagatga acgaactggg ctattcgtgc accgtcaaga cgattcagaa tctgatctac
     5881 tccgacttca gcatcaccta ccatcctatt cgcgagtatt tagactcgct gcctgaatgg
     5941 gacggaacgg attatatcgg tatccttgcc aacagcgtgc atactagtca ccagaaattt
     6001 tgggtagaat gtctggaacg ttatctggtg ggaatgtgcg ctgccgccac acaagatgat
     6061 gtggtgaacc acactgtttt gttgctttgc agcgaaatac agaacatcgg aaagactacg
     6121 tttatcaaca acctgctgcc gcccgaattg cgcgcctatc tttctaccgg tcttatcaac
     6181 ccgagcaaca aggatgatct agccaaaata gcgcaggcaa tgcttatcaa tctggatgaa
     6241 tttgaaggga tgagcggacg ggaactgaat atcttcaagg atttggttac ccgcaaagta
     6301 atcagcatcc gcctgccata cgcgcggcgt tcgcaaaact ttcctcatac ggcttctttt
     6361 gccggcacat gcaattacca ggaagtgctt cacgacacca caggtaaccg ccgttttctc
     6421 tgctttcatg tcgactcgat ggagtttatc aaaataaact acgcgcagtt gtatgcacaa
     6481 atcaagtatc tgctcaacaa gccggggtat cagtattggt tcacccagtc ggaaaactca
     6541 cggattgaag agaacaacga ggatttcatt ttccactcac cggaagaaga actggtgttg
     6601 acacatatcc gcaaaccgga acgtttcgaa aaggtgcatt atctgacggt cactgaaatt
     6661 gcggaattga ttcgcgaacg gacggggtat caatattctc acggaaccaa agcccaacta
     6721 ggaaaagtga tgtccaaaca cggcttcgaa tttcataagg gaaaaaacgg gagaagatac
     6781 actgtattca ttattgatac ggaacaggtg aaatcaaaca ggctatatga ataagatttc
     6841 atctccttcg cacgcaaaaa ggtgagggtt ggtgagggta cttttgcaac ttttcatttt
     6901 tatatttctt atttctattc ttctattttc ttctaaaaaa aaatacgaat gttagaaatt
     6961 taccctcacc taccctcacc ttttcctttt tcttcctcaa aaaaacggta ggaaatttga
     7021 aaaagacagt tatctttttc aaatttccta ccatgttttt tttaatctga atcgaagtta
     7081 tactcctagc acaatactag catcaatatt cagtttttta cttatttcac gagccacttt
     7141 caatgtcggc tcacattttc cggaaatgta gtcactaaga cgcgaaggac taactcctat
     7201 cagttgtgat agtgatttct gattgagccc catttcgtac atacgaagct tcagaacatc
     7261 cacaagcgaa ggttctccca aagaaaagtg ttcctctgaa taatcggcaa caagattaga
     7321 aagaagttcc aactcgatgc tgttagggtc attcaaagga gtatcatcct tcactaacgg
     7381 aagaagatcc tccactctct ttacagccca ttcatactgg gtttggtttt ctatctttgt
     7441 catattttca aatattagca caatctattt tatcatattc tttatgagta ccaataaagc
     7501 gaatatatac aaactttaca gtgaacttca ccactactac caagcgataa ttattccctt
     7561 taacattgaa aacataatgc tggttaccta cactatcggc actattaaag gtcttcttta
     7621 tatcagcgaa acaagcccat tcacttttct ttactatagt aacccattct tgcaaagcaa
     7681 cttttgaatc gggatgctcc tctgcatatt cttttaacgc ttgttctgta aatattctca
     7741 ttagttactc acttatcatg caacaaaaat aagaatataa ttccaatttt caaaattata
     7801 ttccgatatt tgtaattatg gataaaaaga ttcgcttctt ataaagacat cgaaaattcg
     7861 atcctacaac ctaacgcatt catgatgcga tagaaagtag aaaccttagg ttctgtctga
     7921 ccactttcca ctcttgaaat ataagaacgg tcggaaccga tacgccgggc taactctgct
     7981 tgagtaatct tagccttttt ccttgcgtct tcgataattt gcccggtgta gaaagcatac
     8041 gctttttctt ctgcttccgc acgttcggga gtaccttctg ctccaaattt cgcatcaaga
     8101 acagcgtcat aatctactat ttgatgattg tttatctgca taatattcct cctttatttt
     8161 taatgcttta tctatttcac tacccggtgt tttttgcgcc ttcttttgaa agccattaaa
     8221 caacactaca atatttccat catcaaaaat gaaaaatacc cgttatatat taccattata
     8281 ttctgtacga agttcaaaaa ctccgtcctg aacaaatttt acaaatttag tggagagtct
     8341 ttcttgtgtt ttcaacaaga gtagtccata ctggatttta tcttgttcct tttcggttaa
     8401 agtctccatg aaagcctcaa agtaacctcc gtatgtacgg atcttacgtt tcttttccat
     8461 actgcaaata tacgaattgt tgttcaacta tacaacaatc gtctttttat tttatattat
     8521 ttttcctcaa attctccagc acgctttttc ttctcataag acaccagcgt ctctacacta
     8581 agcgttttcc cattcttagg gcttatcaca tctacaacgc ttgctaacgc acgaaaagtc
     8641 tgttcgcaat ttgctactcc gtcatacgtc aacctaccca gattgatggc atcgagcaca
     8701 acagagacat attgcttcgg atttccccga tactcgatga tgacaggcgt gagatgcgac
     8761 atctctcgag tcagttgact gacgattctt ttttttggtc gagcagatcc attaattttt
     8821 cactatgcac attgatttgt gcggttactt cacgaagttc gtctttcaat gaacacaata
     8881 attcatcatt caatgaattt tccataaaac tttctattta attgattata aaaaagccat
     8941 tccagaaaga taagcaatca ttacttactt cccggaatgg tgtctaatac ctcgaaaaca
     9001 aagacttata ttctaaccta atgtactcac tttaatccat ttcttttgat tttgcattcc
     9061 ataccagcaa agcaaacaac accgaaagca aagcagcacc aatccaaaac caattgatat
     9121 aggtgaagtc ataaacatct actccattct gaacagtctt ttgcccttct atcagtatac
     9181 cgctcatcac gtcctgcaat ccggcaccga tataactggc aataccaact actcccaatg
     9241 cagcacccga cgcattacgg ggagcaatat ccactgccat caaaccaccc agaaaacaga
     9301 tcaaaactcc gatacctaaa ccgaaaagaa ccattgccaa cacgtctatc ccaaaatgag
     9361 ctcccggaac taagagaaac aaacaaagag caaacacatt catcaacccg aaaattaacg
     9421 caggaacatt gcgacgtcca ccaaataact tatcggaaat aacacctgaa aacatagtac
     9481 cgattatgcc acagaccgga caaatagaaa tgataaaact ggcatccaag gtggagtaac
     9541 ccttttgagc ttccaaataa aaaacgcccc aactattgat agcataacga ctgatataca
     9601 taaaagcact cgaaagagcc agtatccaaa tggcaggcat cagcaatacc tgacgctgtg
     9661 ctttattaaa atcagccgtt tctgtctcac tcatttcctt tttctgtttg ggaacattca
     9721 ccgaaggaaa tcccatgctt tcgggagtat catggaagaa cttccagacg atcaacgctc
     9781 ctatcaatcc cactataccg gctccgaaga aaccataccg ccagcccaac acactgacaa
     9841 ttgaggctat tatcagaaaa gtcaacgctt cgcctatatt atggctcgca gaccaaaagc
     9901 catagtatga accgcgctct ttgtccgtga accaacggga aagccctact acacaagagg
     9961 ctgctcccat agattgaaac cagccgctaa tcccccaaag gatagcgaac aggataaaag
    10021 aattagtaaa accgagacag aggttaacca aagcggttac caataaaccg gtagtcataa
    10081 aacggttgat attactacgg tcggcaagga aaccgttcgt gaatttcccg atggcatagg
    10141 tgaaaaacaa tacggaacct atgatgccta actctgtttc cgaaaaaatg ccttcatcta
    10201 caataggttt ctttacgaca ttcagactaa gacggcacac ataatacata ccgtaaccaa
    10261 aagtcgcaga aaggaaggta gaccatttca gaaacttcaa acggcgggca tcggatgaag
    10321 acaaagtttc tccgttacaa ggtctcggtg aagagacctt gtaaaaattg attagttgtt
    10381 tcaacatgaa ggaagtgcgt ttaatcgtga agtttcttgt tacgcaaata ctccaataat
    10441 aaagcaggac gatctgtttg aattagcttg gctccctggg caattatcca cccccaactt
    10501 tcatccggct gatgaaattc tactgcacgg tcgtcatcat ggccgccaca gagtttaggc
    10561 cacaaagaat taacaaaaag ccttgcgcca ctatcacgca ctttctgaat caatcgaaga
    10621 gtctcttttt catcattatc aaagactaat tcataagcta tcggtttcaa atgtttctga
    10681 taactatcta ttattttttc agcatcttcc ttatttaaat ttatcactgg cataaaaatc
    10741 actttatcca atacttcccc gttctccact tttacttgtt catagggaag tccagctttg
    10801 ataacacatt ggtcaactgt tcccgttttt tccagaatac aataagcctc tttaaaataa
    10861 tcatacccct tatcaatatt gactaatatt ttgcccttac ataataacat gacttcttct
    10921 aaagtaggaa taagatgagt agtcttgtga gctgctccat tttttagacg aaaacgccgc
    10981 aattcttcca aagtgtaatt ttccggtttc ccttttcctg ttgttgtgcg atcaattgtt
    11041 tgatcatgca tcacaatgag atgtccgtct ttcgttttct tcaagtcaac ttcgaccata
    11101 tcaactccca tatcaataca attttgtatt gcttgcaaag aattttccgg tgcatttctc
    11161 caatcaccac gatgagaaac caccatcacc gaatgattat ttttatctaa caaattcgca
    11221 cgtaactttc tattctgagc atttatcccc gaaatagcaa tgagcaacaa actaaaaatg
    11281 aataactttc tcatattgtt tcagtatttt tatctattga ttctgatttt taaataagct
    11341 ctatcgtcaa aggagcagtt tcccttctta atacctttag tacttttata ttggcgcata
    11401 caaagaggat cattctccaa gatattcatc aaataacatt ctgattccct caaagtcgga
    11461 aacaaacaag gatagccgtc agacgacaag actatttgtg tatgatttcc tatggagaaa
    11521 atacgtacct gatgcatatt aatgggaaaa ccatcaaaaa ccggaaaaga atatggttga
    11581 tttttatcag gattgttttg aagtatagct tgctgctgga gaaaacgata aataaaatta
    11641 cgccctggat cattgctcaa taaatcatcc ggtgtagcac catttaacaa agctatttca
    11701 tttactaccg cacgcgcatt agccattata gcgtcaattt ccttttcatt tgaagagtaa
    11761 gtattaccaa aaagacactg acagtccccg atttgccata tttcattctt ttcataacta
    11821 taaatcactc cattggcagt aaaacggcta ccgggtgttt tctccaactc ttccaacaaa
    11881 cgatgctgaa cataaaaaga atgtattttc tctgttatcc ttttcagagc ttcattggca
    11941 tcaatatctt tagggaaatc gtgtatcgcc tcaatgacca gttccatcgc tatacgcccc
    12001 gtttttttcc atcaatctcc aattccgatt ttgccgtagc tccatcaatg actgctgcaa
    12061 aatagggagt tacaattatc ccatcttcat ttgtagcagg agtatgctta cctttcaaga
    12121 atacttcttc tacatcaaaa ttaggacttg tttgcattgt ccattcattc tctacggaaa
    12181 ggtaatccca attttcaata cattcccatt tctttttcaa ttctttcttt ttcaaataat
    12241 ttattaaata tgcaggtctg tctgtttgca atatagaagc cccgagcgaa tctatcaaat
    12301 agccataacc ttcatccgga tcaactaaag agcaatcatc atcgtgaccg cctgcatggg
    12361 tattccacaa agtattatac caaattcgtg ctcgcccttt catcgcattt tttacatcat
    12421 agggtaatct gttcaaatca gatgcaaatt tgaactctac cgccacagga tttattattt
    12481 gtaaatagtc atccaaacgc tgcattgcat ttttatcgtc caaattaatc tttggcataa
    12541 agacgacctt ttttagatat ttcccatagt tctttttcac ataatctgcc ggagcatcgc
    12601 ttttcattat taccatatcg gtcgttcctg tcttctccaa tagggtataa acctgatcaa
    12661 aataatcaaa agctttgtcc aaattaagca tcactctacc tttagcaaac agtaatgcct
    12721 cttctaaggt cggtacttta taaatagttt ttatatgaca accatttcgc aattgaagtg
    12781 ctttaatttc tgccagcgta tgatctgcaa ccagtccttt gccggtcgtt gtccggtcca
    12841 acttagaatc atgcattaat atcaagtgtc catctttcgt tcttgccaaa tcaacttcta
    12901 caatgtctac ccccattttt actgcattat ctattgcctc tatagaattc tcgcaagcat
    12961 ttcgccaatc acctctatga gaagctacta atacattctt gttttcagga gcaaacagtt
    13021 tattgcgaat actgtctaat ctggtctgag caaatga
//
