LOCUS       gnlProkkaOPMKIGFG_101  13904 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OPMKIGFG_101.
ACCESSION   gnlProkkaOPMKIGFG_101
VERSION     gnlProkkaOPMKIGFG_101
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:45:48
            Original ID  :: gnl|Prokka|OPMKIGFG_101
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13904
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13904
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3553:3904]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3554..3904
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13904
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13904
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             562..2073
                     /locus_tag="ctg101_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCHTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYST
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWQLVSE"
     CDS             2147..3214
                     /locus_tag="ctg101_2"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKMPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(3554..3904)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg101_3"
                     /sec_met_domain="PqqD_RRE (E-value: 8.9e-11, bitscore:
                     32.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.2e-17, bitscore: 54.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQYEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(4002..5390)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg101_4"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5639..6034)
                     /locus_tag="ctg101_5"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(6041..6814)
                     /locus_tag="ctg101_6"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQSAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6820..7347)
                     /locus_tag="ctg101_7"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7334..8575)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg101_8"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8585..9679)
                     /locus_tag="ctg101_9"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQANFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPIVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9684..10724)
                     /locus_tag="ctg101_10"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             complement(10743..11753)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg101_11"
                     /sec_met_domain="PF04055 (E-value: 5e-18, bitscore: 57.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDDMTNLSLKH
                     RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC
                     KMNCKFCMTGKQGYTANLTASQIINQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE
                     LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF
                     SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI
                     PGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKNNES"
ORIGIN
        1 tatgacttgt tgcattgtaa ctcttaatga tgtggtgtct ttaaagttac taaaaagcaa
       61 acatatctac aacttttaat aggattaaga aagaagaaga cagttgaaat aaaaaagaga
      121 ttaccaccaa atttgacgaa gaaccgaaat ctttggttct tcttcaaatt ccgtgctact
      181 tatttatgtt caattacctt attcatggct attccggagt actttaagat gcatatagtt
      241 tggataattt atttgctatt tctaatatgc cgatatccct ttatccatcg gcctttcaat
      301 gagctttact agcacggaat ttgattaaga accaaatctt tttcaggaga aataaaagta
      361 agttcataat ggtgctgcat tgaattattt tttggcggag ttattctaac acttaatagt
      421 tcaaaagcag atatttctct gacccaaaga tagaactaat gatgaattaa aagttgcaat
      481 tatggttttc ttcccacaac aaacgggaaa agtcagaaga atcatgtaca tttgtaatcc
      541 gaaaactaaa agaacatcgc aatgaaaata tttccaagca gcagtatcaa gaaattggac
      601 gcttatacca ttgagaacga acctattgca tcaatcgatc tgatggaacg tgcagcaacc
      661 gtattaacaa aagccatcac agacagatgg aatacggaaa cgccggtcac tatctttgcc
      721 ggaccgggga ataatggcgg agacgctctc gccgtagccc gcatgatggc tgaaaaagga
      781 tataaaatcg aggtatttct cttcaacacg aaaggagaac tttcacccga ctgccaaacc
      841 aataaagaac tggtagaaat gatggaagaa gtaaaattcc acgaaatcag tacccaattc
      901 gtacctcccg tcctgacgcc cgaccatctg gtaatcgacg gattattcgg ttcaggcctg
      961 aacaaaccgt taagcggcgg attcgctgcc gtagtgaaat acatcaattc ctcccctgct
     1021 atggtagtag ccatcgacat tccttccgga ctgatgggag aagaaaacac attcaacgta
     1081 aaagctaata ttatccgtgc cgacgtaact ttcagtctgc aactgccgaa gctcgccttt
     1141 cttttcgcag agaacacgga atttgtcgga gaatgggaag tgctggacat ccaattaagc
     1201 gaagacggta ttgaagagat ggaaacgaac tacgaaatgt tggaaataga gcaaatccgt
     1261 tcactcatca agccacgcaa acagtttgcc cacaagggga acttcggcca tgcactattg
     1321 attgccggtt caaaaggaat ggcaggagcc tctgttctcg ctgcccgcgc ctgcctccgt
     1381 tcgggagtag ggttgctgac tgtccatgcg ccaatgtgca acaacgacat cttgcagacc
     1441 tccatacccg aagcaatcgt agaaaccgac atcaacgaaa cctgttttgc cgtacctacc
     1501 gacacggacg actatcaagc agtcggcatc ggcccagggc tgggacgaaa cgaggaaacg
     1561 gaagctgctt tattggagca actggaacat tgccatactc ctgttgtggt ggatgccgac
     1621 gcacttaata tcctcgccaa ccaccgtcat gcacttaccc acctgccgaa gggttccatc
     1681 ctcaccccgc atccgaaaga actggaacgt ctgaccggca aatgccagga ctcttacgaa
     1741 cgtctgatga aggcttgcga attggctcgt gccgcccatg ttcacattat tttaaaagga
     1801 gcctactccg ccattatcac cccagaaggt aaatgtttct tcaacccaac cggaaatccg
     1861 ggaatggcaa ccggaggtag cggtgacgta ctgaccggag taatcctggc actgcttgcc
     1921 caaggttact caaccgaaga agccgctaaa atcggcactt acattcacgg attggcgggc
     1981 gatgtcgctc aaaagaagca aggaatgatc ggaatgatcg caagcgatat tatcacctgt
     2041 ctgccgacag catggcaact tgtaagcgaa taaaagttaa gaacttaccc ttttttcaat
     2101 aacttcatta actttgtttt caaaaccagt taaaaaagaa ccgaatatga aaaagttgat
     2161 tatagcagca ggactactaa tgacaacgtc cgcctatgca caaaccgaag tactgacagg
     2221 ggttacccga ggaaaagact atggagtggt ttacagtctt cccaaaaccc aaatagaact
     2281 tgaaataaaa gccaacaaag tcaactatac tccgggagaa ttcagcaaat atgctgatcg
     2341 ttacctgcga ctgaccaacg tctccgccga ccctgaagag tactgggaac tggctagcgt
     2401 aaaagtgaaa tccgtaggtg tgcccaacag cgaaactacg tatttcgtaa aattgaagga
     2461 taagacagta gcaccgctca tggaactgac agaggatggc attgtgaaaa cgatcaatgt
     2521 tccttacagc aatagcagtg taggcaaaaa agctgctccc gcccccgcag tcctccaaaa
     2581 gaaagcgaat cctcgtgaat tcctgaccga ggagattctg atggccagct ctaccgccaa
     2641 gatggccgag ctggtggcta aagagatcta taacatccgc gaaagcaaaa atgccttatt
     2701 gcgcggacag gctgacaata tgccttcaga cggagcacag cttaaaatta tgctcgacaa
     2761 tctgaatgca caggaagaag ccatgacgca aatgttctcc ggcacctgca acaaagaaga
     2821 gagaacattc actgtccgcc ttacccctga caaggaattc aacaatgaag ttgctttccg
     2881 cttctcgaag aagttaggtg tagttgccaa caatgatttg gcaggaactc cgttttatat
     2941 cagtctgaaa gacctgaaat cggtcaagat gccacaggaa gatggtaaga agaagaaaga
     3001 tttggatgga atcgcctaca acgtccccgg acaagctatg gttacactga ccgacggtaa
     3061 aaagaaactt tacgaaggtg agcttcctat tactcaattt ggtgtgatag aatatctggc
     3121 tccggttttg ttcaacaaga attctaccat caaagtttat tttgatccga atacgggagg
     3181 attgctcaaa gtggacagag aagaagggaa atagaaaaac gaggaagtaa acttctaaaa
     3241 aacaaagaat atggttggtg aaggacatgc attcgacatg atacgccgaa taaaagaggg
     3301 acgggaagct tcccgcctac gtcgtgaacg tgctaacgat aagttgaagc atctaaaccg
     3361 tgcaaacgaa ccttatccac tacccaacac cacccccgaa gaaatggaac gtatcatcca
     3421 cgactcggag aaaaagaaag agaaagacag caattatttt gtttggggaa cgcttattat
     3481 catgggggtc ctgatagcaa ttgccgtcat actttgggct gtatttatca aataaataat
     3541 aataagttcc tatttatacg actggtatca ccagttttat aaatccatct ttctgcattt
     3601 gagaaagata agccgataca cgcgactcgt agccctcttc atattgaaag tggtctgcga
     3661 gtttttctat aatctcacga acattgcgtt ttccatctat cagttcccat acagccgtac
     3721 cgtgttcttc caatttcaca tgaagttctt tcgacattcc tttcggcaca aggaagcgtt
     3781 gcatccacgg atatttaaaa cggggaaagg agagcacaat tgtctcccct tccctttctg
     3841 ctgtaatatg ttcactgcga cagggaatga cctctaacag gttgattttc tctttggcag
     3901 ccatacttct tattttttat ttcagagtat tcatactgat actcttctgt ttacaccttg
     3961 atacaaaatt cctttgtcac tttaggtatt gaatttccca gttacttttg gatattcgcc
     4021 tcttccagac cgtatccctt cttcttgttc tctgccttta acatcaaagc cacaatcaga
     4081 gcaagcacac caaagagagc aaaaatagcc atcggcaacg tgtagtcata agtctgtgca
     4141 ccgtctacta ccggaccttt gcaataagta ttcaacaccc atccgatcaa caaaggaaca
     4201 cccatcaatc cccagttctg tacccagaaa atcaatgcgt atgcggtacc caactgtttt
     4261 tccggaataa tcttcggaac agacggccac atagctgaag gcaccaacga gaaggcaaat
     4321 cccaatataa tcatgatgat agtagcaaac caccatatat tcagtatagg cagagcgaac
     4381 atcgtatgca caaaaataag catcactgat ccgattatca tcaacgtagc tcccttaccg
     4441 atacggtcat aaagcgagcc gaacaacgga gtcaggataa tcgcaccaat cggcaacaat
     4501 ccgggaatcg ttcccgccaa cttcggatct acattatact tctgcaccat caagtcggca
     4561 gcatacttga taaaggggaa tacagccgag tagaacaata cacatagtaa tgcaatcaac
     4621 cagaatccct tattcgtaat gatatacaca atatctttca tacggaacgg ttcttccggt
     4681 tccaatccct ctgcatccaa agaagcatcc aacttcttat catagaaagt ataaaggaag
     4741 aaagcaatcg tacccacgca caacataatc agacaaaaca aaatcggagc aggaatattg
     4801 gtatggaatg tgccactctc atccgtagat ccgaagaagt cggccaaagg aaccgtgagc
     4861 accattgcca gagttgttcc gatacgtgcc gtagccattt caagtcccat agccaatgcc
     4921 atttccttac ccttgaacca ttttacgata attttggaaa ctgtgatacc ggcaatttcc
     4981 acacctacac cgaagatagc ataccccaat gcggccaggg ttacctgtgt tttgaatcca
     5041 aagagcatgg caccttccgg aaaagtagta gaaatcgcat agtatttcaa tccacaacca
     5101 aacaccatca ataagcaagc ccccattccg gtgaaacgaa ctcccatctt atccaaaatg
     5161 ataccaccga aaatcagcat caacaggaat acattaaacc acccgtaagc gcttgtgaag
     5221 aaaccataat caagactgtc ccatagtagt tctttctcaa gcatgggttt tagaggagac
     5281 attacgtcgg tgaggaaata gccgcatagc atagtaaatg cgaccaatgc tagaacactc
     5341 catcggagta cggcggagtc attcaatttc tgtttcaaat gttctgtcat tgttatattt
     5401 aaaaaagtag ttaataatct tcatacgacc aacaaaggta gttaaatctc gtttgtttct
     5461 atcaaaaaga gattgttttt acaagaaaaa gttaagtgcg gattacactg accacgcgga
     5521 agattgaaaa tccgtgtaat ctgcgtaatc cgcacttaaa tatcaaagaa atgcagcatc
     5581 cgtctgcacc ttcccattaa tggttttacc ccaaagtctt acctgacaac ggagtgaatt
     5641 actctgctgc aggagcagga gtttcagtag ccggtgccgg agtttctgta gcaggtgcat
     5701 tggtagcagg agcttcagtt tgcggcgcag ccgtacctgc gggtaagtta tacgggttag
     5761 tctgttgttc tttctgtgcc tgttccaaca ctgcgtcttt agcaacagca gagcgaggaa
     5821 ctacataagc agtagcaatg ctcattacca ccatgaagat agctaagccc catgttgctt
     5881 tttccagaaa atctgtagtc ttgcgcacgc ccatgatggc gttagatgaa gagaaaccag
     5941 aagcaagtcc gcctcctttt gagttctgaa tcagcacgat gaaacacatc aacaaggctg
     6001 caataaccat taagataacg aataataagt acatttttag ttattttgaa ttagcgttaa
     6061 taatcaattt ctccaaaaat ctgatttggt ctgcaaagta agcatttttt tttggatatt
     6121 tcaagcttaa ttttttaatt atttcaagag cttttgaata tcgttgctgt ttaacataga
     6181 tttttgccaa agtttccgta aaacagctgt catcttcctc ttcttccttc attgtttctt
     6241 cttcggtaag ttcgtccgaa gaggttggcg aagatggcat ttcttctctt aaaggtttct
     6301 tgcagagggg agagtcgctc tcgctctttt ctataaagtc gtcaatcagt tcgtagcctt
     6361 tgagtttggg cgtttcttcg gccgactgtt ccgtggccgg agtctcctcc aaaagataag
     6421 aggtgtaatc catcgaatag tcgaagctgg tgcgggcagt cacctcttcg ggtactgtag
     6481 acaagaaagc gtcgatcaat gctaatgtgc ggtctacgga cggttcgtct ttcagcacct
     6541 ccgtgagagg tactcccttt ttccgtgcct gcacatcata gcggtcacct tcaatcaacc
     6601 ggaacaactg ccgtctgtct gcaatgtaaa gaactgcttt ccgcagttct ccaccgaaac
     6661 taatatcatg gagaatatac agattcttca gatacagcag acgaagtgac tgaaaatacg
     6721 gatacctcgc aagaagattg cgcagttcgt acaaagtatc cctattcagc gtctcgggat
     6781 gctgaatcca ttgttgaaag ttaacagaag tcatttatat taccagtttg ctacagttgc
     6841 attaaaaatt tggtcggtga tctctttaga catttcagca atcaatccgt cctgtacggc
     6901 agtcagcaac tggctagagt cgtaggtacg gaacgcagaa aactgttgtt caaagtcttc
     6961 ggcatgattg gtgttgttga caaaacgtac attgacggta atagtcaact tcgtctccga
     7021 agagtaaccg tcggcagata ctgcctggtt gtactgattg tatcctgtga tttctccgtc
     7081 aatctgcaag tccgcattct gattcggctt gagcagttgc agacgggtct gccggatgaa
     7141 gatatctttc aggtcctcat tgaatttggt tgctaacgga gcatatacat actccgactt
     7201 gatcgggaag tcggctatcg aaatggtctt taccttatca taattgatag acgatccgtt
     7261 aaacttatag gaaacagtgc acgcaatgac taccaacggc aagccgaaca gtaacaaagg
     7321 gcgtattatt ttcttaatcc aattcatatt cttttatttt tctataaagt gtacgctcgg
     7381 aaatattcaa gtccttggcc gcactcttcc gctttccatg atgcctctca agtgccttgc
     7441 gtatcatttc tttctccact tcgtccagtg acaaagggga ttcttctaca tattcttccg
     7501 tgtcttgtat gtcatcatca tccttgcaaa ccgtaggctg catggtgtga atgatagcag
     7561 gtaccgaagg ttgatgcgcc gtcactaccg gagtagtaac caccgttccc atttgtccta
     7621 cctgccccac ctgtccggca cgttccgcca tcaggttgtg caccatcttc ttcagctccg
     7681 ccacttcctg gcgcatatcg aacagaacag aataaagaat ctcccgttcg ctctcaaagc
     7741 ctttactctc acgcgttccc atcaacgcgg gaagacgttg cgtattttgt gcaggaagat
     7801 aattctgcaa gatagcagca gagatctccc tattggtttc aatgatagat atttgctcgg
     7861 tgatgttctt caactgacgc acgtttccgg gccacgggta agccaacaac tctttcttcg
     7921 catcctccgt caactgaata gcgggcatcc ggtatttctc tgcaaagtct gcggaaaact
     7981 tacgaaacaa caaaagtaca tcgtcaccac gttcacgcaa aggcggtatc tggataggca
     8041 ccgtattcaa ccggtaatat aaatcttcac ggaaacgtcc ttctgcaatc gcttgtgtaa
     8101 gattgacgtt ggtagccgcc accacacgca catccgtttt ttgtactttg gacgaaccta
     8161 ctttcataaa ctcgccactc tccagtacac ggagcaaacg tgcctgggta gacatcggca
     8221 actcccctac ttcatcaaga aaaatagtac caccgtcagc ttcgccaaag taccctttcc
     8281 gttcgccaat cgcaccggta aacgcacctt tctcatgtcc gaacagttcg gaatcaatcg
     8341 taccttccgg aatagcgcca cagttgacag caatatactg tccgtgcttc ctccggctat
     8401 attgatgaat aatctgcgga aaactttctt ttccgactcc actttctccg gtaatcagca
     8461 cagacaaatc ggtaggagct acctgaatgg caacatctat ggcgcgcgac aatgcttcag
     8521 tatttccaat aataccgaaa cgctgtttca cttgttgtat ctctgctttc gtcatcactc
     8581 gtttttaatc ttcgtctact gtatccagct tcagtttatc actatcgtca cgtttctcgt
     8641 aatactgttt acgcaacgga ttggcacgag ccactttttc ccgctgacga ttacggaaca
     8701 cgtcgatggc aacatagatt gcctgacgga aagaatcttc acaagccact cccttgcctg
     8761 caatatcgta tgccgttcca tgagccggag aagtacgtac tatcggcagg cctgccgtat
     8821 agttcacccc gtcttccata gccaaggcct taaacggagc cagcccttga tcgtgataca
     8881 tcgccagaat accgtcaaaa tgagtataat tgcccgaacc cataaagccg tcggccgcat
     8941 aaggaccgta gcaaaggatt cctttctctt ccatttcttt catggcaggg ataatcactt
     9001 cctgctcttc cattcccaac aaaccaccgt ctccggcatg aggattgaga gagagcaccg
     9061 caatacgcgg agcgccgata ccgaaatcct gtttcagaca acgatggaat atcatcagtt
     9121 tctcctgaat cagttctttg gtaatcgtag tcgcgatctc tctgacaggg atatgtgtcg
     9181 tcaccaaagc cacccggaag tcattcttca tcaaaatcat caatgactta tcaccattac
     9241 ccagacgttc ttcgatatat tccgtatgtc cggggaagga gaactcttcc gactgaatcg
     9301 tatgtttgtt gatcggagct gttacgataa cgtctatcaa cccttcgcga tattcttcga
     9361 tggcacgttc caaagccccc agcgcagctt taccggcttc ggggtcgggt ttggaaaatt
     9421 ccactttcac ctcatcatcc gtacagttca ccacgctcaa acggttgtac cccgcttcgg
     9481 tagcagagtt gacaatgctg aaattggcct gtatatccag cgctttgcga tgataagccg
     9541 ctactttcgg tgagccataa atgatcggag tacatagttc caacatcgta gggtcggaaa
     9601 atgtcttaag aatcacctca tagcccaccc cgttaatatc tccttgggtg atacctatcc
     9661 ttatcttgtt atcttccatg tttttattta ttagtttgtt ccgcttcctt agatgcttct
     9721 cccaatggaa tctgcttctg ctgaacttca ttcggaagtt tcagtgtata cagagatgct
     9781 tccatctggc gtaccaggtt gcgtttcatt ttatcaggtg aataaacaaa tatttctgct
     9841 gtaataattc gttggttttt ctcgtccaga cgagtatgag atacatacgg accacccata
     9901 aagtcgccct tcatacgcca caggccacgt gcttccattg tgtagctgtt ctgtacattg
     9961 atcggacgga catcggtcag caaactatcg gtcgacatat aaacgccctc cttgaatccg
    10021 gggatattgg ctttcatcac ggagtcacgt ttgtgcacaa aatattcttt ggtaaacgta
    10081 tccttgtcag tgtacggata agagtacatc acaaagttac ggtcggcagt acctgtgttg
    10141 gtagaagccc agaagaaatc atccccggtc tttgaattag ccagttcggc atccacccag
    10201 atgtcgcatc cgaacaaact gtccactttc tgcgaaatga aattactgtg tttcccttcc
    10261 aggaacgtaa tctgacggtt catctccgca cgggtaaaga agtcgacaat cgtctttttg
    10321 ttctcttcca caaacttctc gaactcttct tcgttcggag cctggatagt caatatcatc
    10381 tgcggattgg catacacgtc cttcgcatat ttgaacgagg ctttcgtata tatatcctgt
    10441 atatctacaa taataatgtt acgtatcaac ttcagcgtag aatcataatc tttcggcgaa
    10501 gtatacataa tccggaaaga aggttccgac tgcggcaaac cgggcatatc agcatcgagc
    10561 gcatcatgta aagcccttcc ggcagcacga tcccaaacac cgtgatctac tacaaccaaa
    10621 agctcgtaag cacgaccact agaggtgtga tttcctttca gaccacaaga tgcaacgaca
    10681 aaggctacca aagcgatgca taaaataaaa gagtactttt tcatgatgtt cggttttata
    10741 tattaacttt cattattttt ctcctgtttc gctgtcgaca gcataccgca agcggcaaaa
    10801 atatcttcgc ccctggatga acggatagtg gtgaaaagtc cgtgtgacgt cagataatca
    10861 cgaaaacggg tcatcgtatc catgtccgct ccctcgaggt ctacccccgg tatggcatga
    10921 aaacgaatca gattcaccct gcaatccagc ccgcgaagaa gtttcagcaa ctctttggca
    10981 tagacctgcg aatcattgag ccctttaaaa acaatatatt caaacgaaag tcgacgttgt
    11041 ttactaaaat catagttttt taacagttcc accatttcgg tgattgaaaa cgccttttcc
    11101 gccggcatta attcagcacg ctgaacggtc agcggagagt gaaggctgat ggcaaggtgg
    11161 cagtcatttt cttcgataaa acgctgcaat cctttccgta gcccgacagt agaaagcgtg
    11221 atacgcttcg gactccatgc gtaaccgtag gtagcggtca gtagttccaa tgccttcaat
    11281 acctcatcca ggttatcgag cggctcgccc attcccatca ttacgacatt agtcagtttg
    11341 tcccgttccg gcagcgaatg aatctggttt atgatctggc tggcggtcag gttagctgta
    11401 tacccctgtt tgccggtcat acagaactta cagttcattt tgcagcccac ttgtgacgac
    11461 acgcacaacg ttgcccggtc atcatccggt atataaaccg actctacaaa atggttctca
    11521 cccactttat aaagatactt caccgtacca tctacagagc gcatttcatc taccggagct
    11581 tccgctccca cctcatagtt ctgcttgagc aactcccggt gtttcaatga caaattagtc
    11641 atatcatcaa tcgaggctac cttcttttcg taaagccagg atgcaatctg cttggcagca
    11701 aagccgggca tacccagtct ttttgtcaat gattgaagct ctacaagagt cattcctaaa
    11761 aggggatatt tagacattct tctttctgtt gatagtttat atctgcaaat gtaaggaaat
    11821 aaagtcgatt tccgtatagc aggaatgtaa aagttaacaa aaaagggaag tatgcctccg
    11881 ttatgattca accacgctga tatattgaag tagcttttgc gccatttcag aatcctcgcc
    11941 attctttttc acttcataac cgtacgcctc acggaaacaa gccagcgcct cttcccgttc
    12001 attacaaaag ctgtgcaaaa cccctaagtt ctgacaagcc agaatcgtat cttcttcctc
    12061 ccatcccaga tatttctttc gcagttcaag ctctctgaag aaagcctctt tcgccattgg
    12121 ataattctcc aacttcacat aagcctgtgc tttgtaataa tataccagac aggaagcatt
    12181 agggtcagca tcatcgtgaa aatccaaaga cgttgcaata cgaatcacgt tatcatagtc
    12241 tttattcatg taatactgct gcataatatc acatctcaat gcctcgtagc ggacagtcag
    12301 ttccgccaga cgcggttttt cgctgaaata catttcatgc agaagagact cacggaagaa
    12361 taaagtagac gcctgctcat cgccacgttc attcatcatc cgtttgaatt ccctgcatag
    12421 ataatacaac tgtttatgac aagcgacgat ctgtcttttg ctgtctatct gtatagcaat
    12481 gtccaacgcc tgattcatca gcatccatgc ttcatcgtat cgtttgatat aataaagaca
    12541 tttaccctgc atacgcaaac atttagccac tccaccagac agtctgccat tcaacgactc
    12601 gtgcatttca gctactttcc ggaatttctc ggcagccctc tcttcctcat ccttatagta
    12661 atcacaataa gccagatatt cggaaagttc aatgacttct gcctgactct tctcatcagc
    12721 agaagccgca tgataatcaa gcgccctatt caaataggtc actgcttcat tgtattgctc
    12781 attgtagtaa tatgccagag ctagatttcg gcaggtgttg gcaatctcca gttccggagt
    12841 cggtactatg ttttcctgca tcaccaatgc tttcaggaaa cagtcgcatg ccgtttcgta
    12901 ctcttcatta cgggcatacc ggcatccctc attcatcttc aataccgact tggcaatgag
    12961 tggcatggca gcaccttcca tactcttctc actcacagca gctgccgcct tcgtcagatg
    13021 gaaagaactg ctcaagaaag tagccatatc attagcaatg acaggaatta aaaaagaatc
    13081 gatctcatca aagtccaatt cagcatagac ttcaggcgta acttcaggat tgtcgttcat
    13141 gatcgccttc cagctatctt ccaacagaga acgattcgtg cgatacagaa tctcgaaaat
    13201 ctccacatca caaatccaat ccttcaatat atcccattct tgcatcttat agcattgata
    13261 ggtaatctcc actttatagc gatacgaatc atggtagcag aactgtttca tgcgatagtt
    13321 ataatcggca aaagtcaacg gatgggaaag gatctcttcc tcatccagca gagcggaaat
    13381 aatttcatgg cgactatcat ctatacattc gtcatcttga gcgaaatagc gttcgatcgc
    13441 ctctaccatt tgtgtatcac caatgcaata tcgtcctcct ttgttggtga gccagctgct
    13501 catttccact ctcaactgcg accaaagtat ctgattaatg tctgccatgc tcttcacttc
    13561 atcttcggta aatccttcta aagtaagtga aagcatcaga agcgttcttc caatctcttc
    13621 ggaaccataa tcagccgaca aacgccgtag cacactgtca tagaattgcc caacctcatt
    13681 gagccggcaa tatccacgca tatattcatt gagagcatcg tactgaccga acgaaaccag
    13741 ctcgttgagc aatacactta aacagcgcgg ttgttcagcc agcacccacg aagcaagaat
    13801 atcttcctgc tgtgcagaca aagccttgga gtaagtagac aaatattgct ttgagaacga
    13861 cttggcatcc gcctgtgaaa agccattcaa ctggaaatga gcgt
//
