LOCUS       c00113_gnlPro..        15533 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IHPOLOGB_113.
ACCESSION   c00113_gnlPro..
VERSION     c00113_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:40:44
            Original ID  :: gnl|Prokka|IHPOLOGB_113
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15533
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15533
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2577:5533]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2578..5533
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15533
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15533
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             261..1019
                     /locus_tag="ctg113_1"
                     /transl_table=11
                     /translation="MKRHNYNIAIAITISCILFFINGYHNYIKDKRKDNLEKYKAGYYD
                     NVTVKNKNIEPSTTKNYVPPKNWTKYIIANAFSISVPPTVELRKSNDSYTKDIKNLNWH
                     GHKINSNNVVFQQKGLSVNTPEAHQTYCRIIIDIQKGSLGEYPKFSDYEDLTIEDIHTF
                     QELAKQNSYEYKILGQPEVRWIKIEDTYGIEVEYVRNGANNSRTHVCNYYFFNDNLFAT
                     IILSYRQDDIRKWETDFSNIIKTFKWNNKK"
     CDS             1023..1682
                     /locus_tag="ctg113_2"
                     /transl_table=11
                     /translation="MEKISFMRRLSSSLIDKVLILVLFIISALCISPYGMASHLGSYYA
                     LLDAVPSSYPAQDTYKAMHSVYDNTIYESTEKWVQCYKEISQKPELIAPHKGETLSWDL
                     QITGLFIIVNFIYYLLWEWIFRASLGKFLCGLTVASDNNQPTTEKEIIKRCFLLLLLMI
                     AAVGLRFTFDINYYMTILLFFLIVDTSVIIKGKSLIDIMTNTYITKRKIYKNENLK"
     CDS             1759..2172
                     /locus_tag="ctg113_3"
                     /transl_table=11
                     /translation="LRRDRDSNPGCLAAQRFSRPPQSTTLXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXRRDRDSNPGCLAAQRFSRPPQSTTLPPLQNFFFRSAFLLKRCKD
                     TNHFLFYKLFCTKTEQLYQNSCLYPLRNEHNGI"
     CDS             2578..4806
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg113_4"
                     /sec_met_domain="Gly_radical (E-value: 7.1e-46, bitscore:
                     148.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1169.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFTNGLWNKEINVSDFVSKNIAPYTGDASFLQGPTERTKR
                     IWDICLKALEEERNNNGVRSLDNTTVSTITSHKAGYIDKDNELIVGLQTDELLKRSIKP
                     FGGINVVAKACRENGVEVDDKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLIEAKQEDLRNLTGPMTEARIRLREEVAEQIKALKDIK
                     VMGEYYGLDLSHPATSAQEAVQWVYMAYLAAIKEQDGAAMSLGNVSSFLDIFIEYDLAH
                     GKINETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRVKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKDFCAKVSVDTSSIQYENDNLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKGIPVLTGETL
                     KFEEVMANYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMAFIDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAKVTARRNEIGLTEGFDTEGSFPCFGNNDDRVDHLGVDLVYYFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGPTPEERVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             4808..5533
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 75.5;
                     E-value: 1.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg113_5"
                     /sec_met_domain="Radical_SAM (E-value: 1.9e-30, bitscore:
                     99.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCPFRCLYCANPDTIDVKGG
                     TPTTPEEILQMAISQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKANGIHICLDSNG
                     GIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHEHPFWLRYV
                     LVPGYSDSEEDTRLLGESLGKYQQIQRVEILPYHRLGVHKYEAMGWDYKLKEVKENTPE
                     QLERAEKLFKEYFTNVITN"
     CDS             complement(5602..7806)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 84.6; E-value: 1.3e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg113_6"
                     /sec_met_domain="Fn3-like (E-value: 2.6e-26, bitscore:
                     84.6, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 4.7e-74, bitscore:
                     242.6, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 9.5e-52,
                     bitscore: 168.9, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIILMVCLWGLGNTFTSAQTTEKEKFISSLMKQMTLDEKIGQ
                     LAQCTYRGNFTGPDGGNIPKEEYVRQGRIGSMLNVIGVKDIRRYQELALQSRLRIPLIF
                     GLDVIHGYRTGFPLPLAEAASFDLAMIEEAARYNALESAADGLNWVFAPMVDISWDARW
                     GRVMEGAGEDPYYGSRVAEARVRGLQGDDLADTTTVMACMKHFAGYGAPIAGKEYNSVD
                     MSMGHFANFYMPPYKAAIKVGAATVMSAFNDFNNIPCTANDFLLNRLLREQWGFKGFVV
                     SDYNSVEELVNHRYAVDKKDAAAKALNAGLDMEMVSTCYLTYLKELVQEGKVKESVLDD
                     AVRRILEKKYELGLFEDPFRYCNPERAARILNAPEVRNASLRMAERSVVLLENRESVLP
                     LTAQTRKIALIGGLSKSQYDMAGAWAATTDRNKVVTLYDALVRKGLEVSYAEGYDMKSN
                     QLTGLQEALQAAEASDVIVVAVGERFGQSGEKASKVNIAIPEGQQKLVSELAKTGKPVI
                     ALVMCGRPVIFNEIREHADAVLCTWWLGSEAGNAICNVLWGEYNPSAKLPMTFPAHVGQ
                     IPIYYQNKSTGRPTALKQTYKASYIDASTEPAYPFGYGLSYTDFGYSDLKLLPGKAAGV
                     HTEVSVKVTNTGKCAGEEVVQLYVQDKVASVTRPIKELKGFRKIHLNVGESKTVAFQIT
                     DDALGFYDNEMNYMVEPGDFVFMVGGSSDDVQQITYNLKE"
     CDS             complement(7837..10299)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 80.1; E-value: 3.4e-25)"
                     /gene_kind="other"
                     /locus_tag="ctg113_7"
                     /sec_met_domain="Fn3-like (E-value: 7e-25, bitscore: 80.1,
                     seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 7.3e-56, bitscore:
                     182.8, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 4.7e-50,
                     bitscore: 163.4, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKKVALSGLLLCCAITAKAQVCITPQVEQRARELVSQMTLEE
                     KIDYISGPKSFYIRAVPRLGIPEIRMADGPQGIRNNTQSTLYPCGILSASTWNRKLARE
                     LGHGLARDAKARGVSILLGPGVNIYRSPLCGRNYEYFGEDPYLTGETAKEYILGVQEEG
                     VMATVKHFAANNQEWSRHHASSDVDERTLQEIYFPAFRKAVQEAGVGAVMDSYNPLNGV
                     HATENSWLNIDVLRKQWGFKGILMSDWTSVYSGVGAANGGLDLEMPVGKFMTREILIPA
                     IENGIVKEETIDAKVRHILQTLIAFGALDTPREDKSIDKDNAQSKEIALDLAREGVVLL
                     KNDNGTLPYRNGRTLVIGPNADIIPTGGGSGFVTPYSVVSLYDGMVQLKGGRQIELLSD
                     SILYKDMSQQIYTDGSFTQNGFKGEYYNTRNLTGELFQAAIEPAIDHAWKYGAPFDGMP
                     VDQFSARWTGVYKADKDGTVKFQLAGDDGYRLFVNDKLITGDWGNHSFSTRSAFMQVSA
                     GEIYRLRIEYFDNVGEATVSFQAGMMDEERLASSLKHARNVIVCAGFNSSTEGEGFDRP
                     FALSYGQEYLINKVASLHDNVAVVVNAGGGIDFRNWGQSVQAILMAWYPGQEGGKALAE
                     IITGKLSPSGKLPVSIEEKWEDNPVYGNYYDNRNVPHKRVQYAEGVFVGYRGYDRNGKQ
                     PLYPFGYGLSYSSFEYSNLSVEKTGGSRVTVSFDIKNTGKMDAAEAAQVYVRDVECSVP
                     RPLKELKGYDKVYLKKGETKRVRILLDEEAFAYYDVESHRFVVEKGTFEILAGPSSADL
                     PLKATVVL"
     CDS             complement(10476..11789)
                     /locus_tag="ctg113_8"
                     /transl_table=11
                     /translation="MEDELWLKKIKDKLEDYSEPLPVAGWERLEKELSVSGAPITGPHR
                     MIPFRRWAVAAAAVLLVAVSSVSLWLLQSPVGNEMRHTSVPALAVAPDVLPEQTVPAIR
                     TNSIEPAYRAHGNASAPNKEASHPLVAQHIRISVGEEQQEEMLPVETADEVVGIGQQAE
                     EPVVEDTDHETTMQTEEPETREDRYRPSGRDKLHLPEKNSSGRDAKGWAVGLSVGNTGG
                     FSLANEGEANVMSDYMPGSPIYGGNVDLSSTANGIVTIPDGQELVFKDGMPYLQRREKK
                     IADIDHKQPLSFGVSVRKNLAKGFSVESGLTYTYLASDVRYEGSSEKISQKLHYIGIPV
                     RANWNFVDAKNFTMYVSAGGAIEKCVYGKIGTESETVKPVQLSVMGAVGAQYNISNRVG
                     LYVEPGVSYFFDDGSSIQTIRKENPCNFTLQAGIRLTY"
     CDS             complement(11802..12350)
                     /locus_tag="ctg113_9"
                     /transl_table=11
                     /translation="MEEQELAERCRQGDNLARKELYERYAGRMLSVCLRYAGDRETAQD
                     LMHDGFLKLFDSFDKFTWRGEGSLRAWMERVMVNTVLQYLRKNDVMNQSSALENAPEAY
                     EEPEGSSIDVIPQKVLMQFISELPAGYRTVFNLYIFEEKSHKEIARLLGINEKSSASQL
                     TRAKATLAAKVREWMKRND"
     CDS             12531..13235
                     /locus_tag="ctg113_10"
                     /transl_table=11
                     /translation="MKKLRMTLATSMLLFLTAIVLQSCLDDWDDKYDTLFAVGTVKVIE
                     GKDYYFSLDEGSKLYPSDTTYVHDYAVTDGQRAFIYFRELEEKLPGYEYNAQIKHIENI
                     LTKDIYSMPAEKADSIGDDNINATDLWITGEYLNIKYQFYHSNNEDKKHMLNLVINEAS
                     TGENDKPDYVNLEFRHNAYNDSQLTLGTGLASFKLDNIAEQLKEKKGLNIRVKSLYDGE
                     RFMTIDIKKENN"
ORIGIN
        1 tttaaggggg cattgttgaa tgttttaagg gggcagaatc gcttggtttt agggggcagc
       61 ttacactgga ttttccacca ttacccaaag gttataatag acttctcatt gtttttgctt
      121 gtcttattat tgtttatacc gtacatgaat atcctgaaaa ggttaacact tttttcttca
      181 cgctgctagt tgagattatt acttatatag ctactatatg gatttatcgt ggatttaaag
      241 aattacccta aaataaaaat atgaaaagac ataattataa tattgcaata gctatcacaa
      301 ttagttgtat tctttttttt attaatggtt accataacta tataaaagat aaaagaaaag
      361 ataacttaga aaaatataaa gccggatact atgacaatgt aacggtcaaa aacaaaaata
      421 tagaacctag tacaacaaaa aactatgttc ctcccaagaa ttggactaaa tacataatag
      481 caaatgcttt ttctattagt gtacctccta ctgttgaact aagaaaaagt aatgattcat
      541 acactaaaga tattaaaaat ctgaattggc atggacacaa aataaatagc aataatgttg
      601 tttttcaaca gaaagggtta tctgttaata cccccgaagc gcatcaaaca tattgccgaa
      661 ttataataga tatccaaaaa ggaagtctag gagaataccc taaattttca gattacgaag
      721 atttgactat agaagacatc catacatttc aagaactagc aaaacagaac tcttatgaat
      781 ataaaatttt aggtcaacca gaagtgcgct ggattaagat tgaagatact tacggaatag
      841 aagttgaata tgtgcgaaat ggagcaaaca attcccgtac tcacgtctgc aattattatt
      901 tctttaatga caatctattt gcaacaataa tattatcata tagacaagat gatataagaa
      961 aatgggaaac agatttttca aatataatta aaacatttaa gtggaataat aaaaaatgag
     1021 ttatggaaaa aattagtttt atgcgaagat tatcaagttc tttaatagac aaagtcttaa
     1081 tcctggtatt atttattatt agtgctttat gtatatctcc ctacggaatg gcttctcatt
     1141 taggaagtta ttacgcccta ttagatgcag tcccatcatc ttatcccgct caggatacat
     1201 ataaagcaat gcatagtgtt tatgacaata ctatttatga aagtacagaa aaatgggttc
     1261 aatgttataa agaaatatca cagaagcctg aattaatagc tccacataag ggtgaaaccc
     1321 tatcttggga tttacaaata acggggcttt ttataattgt aaattttata tattatcttt
     1381 tatgggaatg gatatttcgc gcatcactag gcaaatttct atgtggactt actgttgctt
     1441 ccgataataa tcaaccaaca acagaaaaag aaattatcaa acgctgtttc ttattactac
     1501 tcttaatgat agccgcagta ggtctaagat ttactttcga catcaattat tacatgacta
     1561 ttttattgtt tttcctgatt gtagacacat ctgtaatcat aaaagggaaa tcattaattg
     1621 atattatgac taacacatat atcacaaaaa gaaaaatcta taaaaacgaa aatcttaaat
     1681 aaaacaaaac acccagtttt acattatagg gtgtaaaact gggtgtaaat cttataaacc
     1741 gctaattatc aaggtttatt gcggagagac agggattcga accccgggtg cctcgcagca
     1801 caacggtttt caagaccgcc gcaatcgacc actctgnnnn nnnnnnnnnn nnnnnnnnnn
     1861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1921 nnnnnnnnnn nnnnnntgcg gagagacagg gattcgaacc ccgggtgcct cgcagcacaa
     1981 cggttttcaa gaccgccgca atcgaccact ctgccacctc tccaaaactt ctttttcaga
     2041 agtgcttttc ttttaaagcg gtgcaaagat acaaatcatt ttttattcta caaacttttc
     2101 tgcacaaaaa cagagcaatt ataccaaaat tcttgtttat acccactacg gaacgaacat
     2161 aacggcattt aggctatttg ttgaaattta tcaagggcaa gacagagttt tataacttac
     2221 tggctatcag tatatttaca aagagccaca ttcagtatac gattgaaccc tattcagtat
     2281 acgactgaat ggcattcact atacgactga attaggttca gaatacgact gttccttaaa
     2341 cctacatcat ttgtaaataa tgcagattat tattcggttc ttgtttcaat tcataaacca
     2401 catataaaga aagtattaac atctctactc ccccggacat tcactaccta ataatagtta
     2461 ttttatgctg ttcaacataa aaagagaagt atctcttata aaattacgga atttattcag
     2521 tatttttgcg cgctctaaag gataacatta tctaacctac taacaaaaac aaattttatg
     2581 gaattgaaca aaacctttac caatgggctt tggaataaag aaatcaatgt cagtgatttc
     2641 gtcagtaaaa acatcgcacc ctataccggg gatgcatctt tcttgcaggg acctaccgaa
     2701 cgtaccaaac gtatctggga catctgtctg aaggctctcg aagaagaaag gaacaacaat
     2761 ggcgtccgtt cactggacaa taccaccgta tctaccatca cttctcataa agccgggtat
     2821 attgataagg acaatgaact tattgtcggt ttgcagactg atgaactgtt gaaacgatcc
     2881 atcaaacctt tcggaggcat caacgtggta gcaaaagcat gccgtgaaaa cggagtggaa
     2941 gtggacgata aagtaaaaga catcttcacc cattaccgca aaacacataa cgacggcgta
     3001 ttcgatgtat ataccgaaga aatccgttcc ttccgctcac tgggattcct taccggattg
     3061 cccgacaact atgcccgcgg acgtatcatc ggcgactacc gccgattggc tctctacggc
     3121 atcgaccgtc tgattgaagc caagcaggag gacttgcgca acctcaccgg cccgatgacc
     3181 gaagcacgca tccgtctacg cgaagaagtg gcagaacaaa tcaaagcttt gaaggacatc
     3241 aaggttatgg gcgaatatta cggactcgac ctcagccatc cggctacatc agctcaagag
     3301 gccgtgcaat gggtatacat ggcatatctt gctgccatca aagagcagga cggagcagcc
     3361 atgtcactgg gtaacgtatc ttcgttcctc gatatattca ttgaatacga tctggctcac
     3421 ggaaaaatca atgagacgtt tgcacaggaa ctgatagacc agttcgtcat caagctgcgc
     3481 atggtacgcc atctgcgtat gcaatcatac aatgatatct ttgccggtga cccgacttgg
     3541 gtgaccgaag ccatcggagg acgcttcaat gacggacgcg tgaaggtcac caagacttct
     3601 ttccgctttt tgcagacgct atacaacctc ggtccttctc cggaaccgaa cttgaccgta
     3661 ttgtggagtc ccgaactgcc ggaaggcttc aaggatttct gcgccaaagt ttctgtagat
     3721 accagctcca tccagtacga aaacgacaac ctgatgcgtg aagtgcgcaa ctgcgacgac
     3781 tacggcatcg cctgctgtgt atcctaccaa gccatcggca aacaaatcca gttcttcggc
     3841 gcacgtgcca accttgccaa ggccctgctg ctcgccatca acggtggacg ttgcgaaaat
     3901 accggaactg tcatggtgaa aggtattccc gtattgaccg gtgagacatt gaagtttgag
     3961 gaagttatgg ccaactacaa gaaggtactg actgaaatag cccgtgtcta caacgaggcc
     4021 atgaatatca tccactacat gcatgataag tattattatg agaaagccca gatggcattc
     4081 atcgataccg acccacgcat caatctggca tacggtgttg ccggcctttc catcgccata
     4141 gactcactgt ccgccatcaa atatgccaaa gtcactgcac gccgcaacga aatcggcctg
     4201 accgaaggtt tcgacactga aggttcattc ccctgcttcg gcaataatga cgaccgtgtg
     4261 gaccacctgg gagtagacct cgtttactat ttcagcgaag aactgaaaaa gctgcctgtc
     4321 tacaagaatg cccgtcccac cctttccttg ctgactatca cctccaacgt gatgtacggc
     4381 aagaagaccg gtgccactcc ggacggacgc gccaaaggtg ttgcctttgc tccgggtgcc
     4441 aacccaatgc acggacgtga caagaacggt gccatcgctt ccttgagctc cgtagccaaa
     4501 ttgcgctacc gcgactcgca ggacggcatc agcaatacgt tctccattgt tcccaaatca
     4561 ctgggcccga caccggaaga acgtgtagag aacctggtaa ccatgatgga cggctacttc
     4621 accaaaggtg cccaccattt gaacgtaaac gtactgaacc gcgaaatgct ggaagatgcc
     4681 atggaacatc ctgaaaagta tccgcaactc accatccgcg tttccggcta tgccgtgaac
     4741 ttcgtgaagt tgagccgcga gcatcagttg gaagtcatca gccgttcatt ccacgaaaga
     4801 atgtaatatg ataaatgtac actcctacga aagtatggga acattcgacg ggccgggtct
     4861 ccggctcgtc gttttcctgc aaggatgtcc gttccgttgt ctgtattgtg ccaatccgga
     4921 tacgattgat gtaaaaggag gcactcccac cactccggaa gagattctgc aaatggctat
     4981 cagccaaaag gcattcttcg ggaagaaagg aggtattact ttctccggcg gtgagcctac
     5041 cctgcaagca gaagcgctga ttcctctttt caaggagctg aaggcgaacg gcatccatat
     5101 ctgtctggac agtaacggag gcatctggaa tgaaaaggtg gaagagctct ttagcctgac
     5161 tgacctcgtg ctgctggaca tcaagcaatt caatcccgaa cgccaccgta cgctgacggg
     5221 acgaagcaac gaacagacac tccgcaccgc tgcctggctc gaagaacatg aacacccctt
     5281 ctggctgcgc tatgtactgg tccccggtta cagcgattcg gaagaagaca cccgcctgct
     5341 gggtgaaagt cttggcaaat accagcagat acaacgggtg gaaatacttc cttatcaccg
     5401 tctgggtgtt cacaaatacg aagccatggg atgggattac aaattgaaag aagtgaagga
     5461 aaatactccg gaacaactgg aacgggcaga aaaactgttc aaagagtatt tcacgaatgt
     5521 gataaccaac taaaacagaa aagcaaggct gtccggatat gattccagac agccttgctt
     5581 ttcatttata gggtaagaat cctattcttt caagttatag gtaatctgct gtacatcatc
     5641 actactgcca cccaccataa agacgaaatc accaggttct accatataat tcatctcatt
     5701 gtcatagaat cccagtgcat cgtcagttat ctgaaaagct acagttttgc tttcacccac
     5761 attcagatga attttcctga agcccttcaa ttcctttatc ggacgcgtaa cagaggctac
     5821 cttatcctgc acatacaatt gaactacttc ctctcctgca cacttaccgg tattagtcac
     5881 ttttaccgac acctccgtat ggacgcctgc agccttgccc ggcagcagtt tcaaatcaga
     5941 atatccaaaa tccgtgtacg aaagcccata tccgaaagga taggcaggct cagtggaagc
     6001 atcgatataa gatgccttat aggtctgttt caatgcggta gggcggccgg tgctcttatt
     6061 ctgataataa atgggaatct gtcctacgtg tgcaggaaat gtcatgggca atttagccga
     6121 aggattatac tctccccaca acacattgca tatggcattg ccggcctcac ttcccagcca
     6181 ccaagtacac agtaccgcat cagcatgttc ccttatctca ttgaagatta ccggacgccc
     6241 acacatgaca agagcaatga caggttttcc agtctttgcc agttccgaca ccagcttctg
     6301 ctgcccctcg ggtatggcta tattcacttt ggaagccttc tcgccactct gaccgaatct
     6361 ctcgcctacc gccacaacaa tgacatccga agcctcagca gcctgtaatg cttcctgcaa
     6421 tccggtcaac tgattgctct tcatatcata gccttcagca tagctcacct ccagtccttt
     6481 ccggaccaat gcatcatata aggtcaccac tttgttccgg tccgtagtgg cagcccaagc
     6541 acctgccata tcgtactggg attttgagag tcctcctatc aaggctatct tcctcgtctg
     6601 tgccgtcaac ggaagcacag attccctatt ctccagcaat acaacggaac gctcggccat
     6661 acggagcgaa gcattacgga cttcgggcgc attgagtatt ctggccgctc tttccggatt
     6721 acagtagcga aaagggtcct caaacaatcc caactcatat ttcttctcca atatacgccg
     6781 tactgcatca tcaagcacac tctcctttac tttcccttct tgaacaagct ccttcagata
     6841 agtcaagtag caggtactta ccatctccat gtccagacca gcattcagcg ctttggctgc
     6901 ggcatctttc ttgtcaacag cataacggtg gttcaccaat tcctctaccg aattataatc
     6961 ggacacaaca aatcccttaa atccccactg ctctctcaat agccggttga gcaagaaatc
     7021 attggcagta caaggaatat tattaaaatc attgaaagca ctcatcacgg tagctgctcc
     7081 tacctttatg gccgccttat agggaggcat ataaaaattg gcaaagtggc ccattgacat
     7141 atccacacta ttatactcct ttcctgctat cggtgcacca tatccggcaa aatgtttcat
     7201 acatgccatg acagtcgtcg tgtctgccaa atcgtctcct tgcaagcctc tgacacgcgc
     7261 ctccgctacc cgagaaccat aataagggtc ctcaccggcc ccttccatga cgcgtcccca
     7321 acgtgcgtcc cacgaaatat ccaccatcgg ggcaaaaacc cagttcaaac catcagcggc
     7381 actttccaaa gcattgtagc gtgcagcttc ctcaatcatg gccaaatcga aacttgcagc
     7441 ctcggcaagc ggaagcggaa atccggtacg atagccgtgg ataacatcca gtccgaaaat
     7501 taaaggaatg cgcaaacgcg attgcaaagc aagctcttga taacggcgta tatcctttac
     7561 tcctatcaca ttcagcatag agcctattct gccttgccgg acatactctt ctttaggaat
     7621 atttccaccg tcgggtccgg taaaattccc tcggtaggtg cattgtgcaa gctggcctat
     7681 cttttcatcc agcgtcatct gcttcatcaa gcttgagatg aatttctcct tctccgtagt
     7741 ttgtgccgag gtaaaggtgt taccaagtcc ccacagacaa accatcagta ttattatctt
     7801 tttcatactg ccattcttgt tttgatattt attttatcat aaaacaacag ttgccttcaa
     7861 tggtaaatca gctgaagaag gacctgccag aatctcaaaa gtcccctttt ccactacaaa
     7921 ccgatgtgat tccacatcat agtaggcaaa ggcttcctca tccagcaata tccgaacgcg
     7981 cttggtttca cccttcttca agtaaacctt atcgtagcct ttcaactcct tcaatggacg
     8041 cggaacagaa cattccacat cccgcacata tacctgagcc gcttccgcag catccatctt
     8101 tccggtattc ttgatgtcaa agcttaccgt aacccggctt ccccccgtct tctcaacact
     8161 cagattacta tattcaaaac tactgtatga cagtccatac ccgaaaggat agagcggctg
     8221 ctttccgttc cggtcatatc ccctataacc tacgaaaaca ccttcggcat actgcacccg
     8281 tttatgaggt acattgcgat tgtcataata attaccatat accggattat cttcccattt
     8341 ttcctcgatg ctgactggta gtttgccact tggcgaaagc ttgcccgtaa tgatttcggc
     8401 aagggccttt ccaccctcct gccccggata ccatgccatc aaaatagctt gtacactctg
     8461 cccccaattg cggaaatcta ttccacctcc ggcattcacc accacagcca cattatcatg
     8521 aagtgaagcc actttattaa tgagatattc ctgcccgtat gacaatgcaa acggacggtc
     8581 gaacccttca ccttctgtac tgctgttgaa cccggcacat acaataacat tcctggcatg
     8641 cttcagtgaa gaggccaaac gctcctcatc catcattcct gcctggaaac tgacagtcgc
     8701 ctcacccaca ttatcaaaat attcaatacg caaccggtat atctcccctg cactgacctg
     8761 cataaatgca ctgcgggtac tgaatgaatg gttcccccaa tctccggtaa tcagcttatc
     8821 gtttacaaac agacggtatc cgtcatcgcc agccagctgg aacttgacag ttccatcctt
     8881 gtcagccttg taaactcccg tccaacgggc agaaaactga tctaccggca tgccgtcgaa
     8941 cggtgcaccg tatttccagg catggtctat ggcaggctct atggcagctt gaaagagttc
     9001 tccggtaaga ttacgagtat tataatattc gcccttaaaa ccgttttgcg taaaactgcc
     9061 atccgtataa atctgttggg acatatcctt ataaagaatg ctgtcagaca gcagctctat
     9121 ctgtctgccg cccttcaact gaaccatacc gtcatagagt gacactaccg aataaggggt
     9181 gacaaatccg cttcctcctc ctgtgggaat aatatcggca ttaggcccga ttaccaatgt
     9241 tctaccgttc cggtaaggca acgtaccgtt atcatttttc aataagacta ctccttctct
     9301 cgccaagtca agtgcaattt ccttagactg tgcattgtct ttatcgatag atttatcttc
     9361 tctcggagta tcaagtgctc caaaagcaat caatgtctgg agtatatgcc ggactttggc
     9421 gtcaatggtc tcttccttca cgataccatt ctctattgcc ggaataagaa tttccctggt
     9481 catgaattta ccgacgggca tttccaaatc caaccctcca ttagcggctc ccacaccaga
     9541 atatacagat gtccagtcag acatcaggat acctttaaat ccccactgct tgcgtaatac
     9601 atcaatgttc agccagctgt tttcggtggc atgtaccccg ttcagcggat tatagctatc
     9661 cataaccgcc cctactcctg cttcctgcac agcttttcgg aacgcgggaa aataaatttc
     9721 ctgcagcgtg cgttcatcca catctgagct ggcatgatgt ctgctccact cctggttatt
     9781 ggccgcaaaa tgcttcaccg tagccataac tccctcttcc tgcactccca agatatattc
     9841 tttagcagtt tcgcccgtca aataagggtc ttcaccaaaa tactcatagt ttcgcccgca
     9901 tagaggagag cggtagatat tgactccagg ccccaacaga atacttaccc cacgggcctt
     9961 tgcatcccgg gccaaaccat gtcccagctc tctagccaac ttacggttcc atgtcgaagc
    10021 cgacaagatg ccacaaggat acaaggtact ttgagtattg ttacgtatgc cttgcggacc
    10081 atcggccatc ctgatttcgg gtatgccaag ccggggtaca gcccggatat aaaaagattt
    10141 gggaccggaa atgtaatcga ttttttcttc cagcgtcatt tgagaaacca actccctggc
    10201 acgctgctcc acctggggag taatacacac ttgtgctttt gccgtgattg cacaacaaag
    10261 caatagcccg cttaaggcta ctttcttttt aatcttcatt ttgtctattt tactacgtgt
    10321 ttgttatatt gccgggcatg tcccgaccta ctttctttct tctcaatcaa taaaaaaccg
    10381 tgtcccttca tccaccaacg aagaaacacg gccgaaagtt attaagaaaa ttctgaatct
    10441 acaagaaagt ggacaaaaac atgtctgtcc tgctatcaat aagtaagacg tataccggcc
    10501 tgcaacgtaa agttacacgg gttctccttg cgtatagtct gtatcgacga accgtcatca
    10561 aagaaataag atactcccgg ttccacatac aggcccaccc tattgcttat gttatactgg
    10621 gcaccgacag cacccatgac agaaagctgt accggtttca cagtctcact ctcagtacca
    10681 atcttgccat acacacattt ttcaatggca ccccccgccg aaacgtacat cgtaaagttc
    10741 tttgcatcca caaagttcca gttggcccgt accggaatgc caatataatg cagcttctgg
    10801 cttatctttt ccgagctgcc ctcatacctt acgtcagaag caagataggt atacgtcagc
    10861 ccgctttcca cagagaaacc cttcgccaag tttttccgca ccgaaacacc gaaactgagc
    10921 ggttgtttat ggtctatatc cgcaattttc ttttcgcgtc tttgcagata gggcatacca
    10981 tccttaaaaa ccagttcctg cccgtcggga atagtaacaa tgccattggc cgtagaggat
    11041 aaatctacgt taccgccata aataggactt ccaggcatgt agtccgacat cacattcgct
    11101 tccccttcat tcgccaatga aaaacctccc gtatttccta cggacaagcc aaccgcccat
    11161 cctttagcat ccctaccaga actgtttttt tccggaagat gcagtttgtc ccggcctgac
    11221 ggacgatagc ggtcttccct tgtctccggt tcctcggtct gcattgtagt ttcatggtcc
    11281 gtatcttcca ctaccggttc ttccgcctgc tgtccaatac cgacaacctc atctgcagtt
    11341 tcaaccggca gcatttcctc ctgctgttct tcgccaaccg atattctgat atgttgtgca
    11401 accaaagggt gacttgcctc cttattgggc gccgatgcat ttccatgtgc ccgataagca
    11461 ggctctatgg aattagtccg tatggcaggt actgtctgtt ccggcaagac gtccggagcc
    11521 acagccaaag cgggcactga cgtatgccgc atttcattcc ctaccggact ctgcaacagc
    11581 cacagactga cggacgaaac cgccaccagc aacacagctg ccgcggccac cgcccagcga
    11641 cggaaaggta tcatcctatg cggtccggtt atcggagctc cggaaacgga caattccttc
    11701 tccaaccgct cccatccggc aaccggcagc ggttcggaat agtcttccag cttgtccttt
    11761 atctttttca accacaattc atcttccata cgttccttca tttaatcatt tcttttcatc
    11821 cactcacgta cttttgccgc taaagtcgct ttagcacgcg tcaactgcga ggcagaggat
    11881 ttttcattaa ttcccaatag tcgagcaatc tccttatggg atttctcttc aaaaatatat
    11941 aagttgaata cggtacgata gccggcaggc aattcactga taaactgcat tagtaccttt
    12001 tgaggaatga catctattga cgaaccttcc ggttcctcat aagcttcagg tgcattctcc
    12061 aaggccgatg actgattcat cacatcattt ttccgcaaat actgcaacac cgtattcacc
    12121 attacgcgtt ccatccatgc ccgcagagaa ccctctcccc gccaagtgaa cttatcgaaa
    12181 gaatcaaaaa gtttcagaaa accgtcatgc atcaggtctt gggcagtctc ccggtcacct
    12241 gcataacgaa ggcatacgct gagcatgcgt cccgcatagc gctcatacag ttctttgcgg
    12301 gcaagattgt ctccttgcct acagcgttct gccaattcct gttcttccat tctctctttt
    12361 aacacgtgtt taccctataa atgcaatcgg cgcaaaaata ctgcatcagg cagagaagaa
    12421 aatcatactt tcatttcttt aacagtatac tacgcagtat ttagcttttc accgcatttt
    12481 ctgaatacaa aaataagttt taaacagaaa agagctaaaa cctaccactt atgaagaaac
    12541 tgagaatgac attggcaaca tccatgcttt tattcctgac tgccattgta ttgcaatcat
    12601 gcctggacga ttgggatgac aaatatgaca ctttgttcgc cgtaggtacg gtaaaggtca
    12661 tcgaaggaaa agactactat ttctcactgg acgaaggcag taaactatat cccagtgaca
    12721 caacctatgt tcacgactat gccgtaacag acggccagag ggctttcatc tacttccgcg
    12781 aactggaaga gaaacttcca ggctacgaat acaatgccca aataaagcac atcgaaaata
    12841 ttctgaccaa agacatctac tccatgcctg ccgaaaaggc ggacagtatc ggagacgaca
    12901 acatcaacgc cacggattta tggattacgg gtgagtatct gaacatcaag tatcaattct
    12961 accacagtaa caacgaagat aagaagcaca tgctgaacct ggtcatcaac gaagcatcca
    13021 ccggcgagaa cgacaaaccg gattacgtca atctcgaatt ccgccacaat gcctacaatg
    13081 acagccagct cacactgggc accggactgg cctccttcaa gctggacaat atagcggaac
    13141 agctgaaaga gaaaaaagga ctgaacatcc gcgtcaaaag tctatatgac ggtgaacggt
    13201 tcatgaccat agacattaaa aaagaaaaca actaaatctc ctgaaaacac atttttcaac
    13261 atctcaatga gaagcggagt aacatttcaa tatgttgctc cgctttgttt ttccataact
    13321 tatcagaatt cattgttcaa gcaagtcagc ctcaacgaag cgttgaacgc ttcggcagac
    13381 aatcgcgtcc tgacctgtac ctgcacgctg ctcttcggct ggacatcaaa ataattgtcg
    13441 ctatatacac tttcattgtc agcaacggac aagcatacgg cacgggcaaa cttgtctgtt
    13501 gataccgtca cttcatatcc gccttcaatg gaacggactt cggtctgcaa atccactttc
    13561 ggataattca tattcttctg cttgtccaga cagtagttgt tatggtacac cctgcccgat
    13621 ttgtccgtat agtctacgcg gacatatacc gttcctctat ctgccccctc cagcagcttg
    13681 gcaagcggtg cggaaaaaca gacacggctg tcattaccgg aaatgccgac agatttgtcc
    13741 cagtgataaa ccacagtgcc gtcgaaccgg cagacctgga gctgcagccg gccggaagta
    13801 ttctccaagc ggtcggacac tgcatatact ttcaaatcat ccccctccac caccggagaa
    13861 atcaggatgt catcatagac cttgcgagta taatagtgct gcgccttcca gcgtccgtaa
    13921 tagtcacggc tcgcccagga agctacgggc caacagtcgt tgtgctgcca gaaaagcgtc
    13981 cccatattat acggcatctg gcggcggtgc gactcgatgg ccgtcttgat ggcatctccc
    14041 tgcagcacat ggttcatata aaggaatgcc cggaaatcac gcggcttttt atattcattc
    14101 aataggtaag tctcaatcag cccgttggca tggtcgccac cacgctgatg ggacatcatc
    14161 acctcggaac gtatatccca gtcttcgggg taaggagcat agcgcttgac ggagtcgaac
    14221 tctggaaaag actgaaagcc gtactcgctg aaaaagcggg atttctcgct gtcataatcg
    14281 gaaatgggtg ctttaccatg ccagacactc caatagtgac ggtccccgtc agtagtaccg
    14341 gacatctctc cctcgaatgc gaacggagaa gaaggccaat agaaggttcc gggtgcatac
    14401 tccctgacca ccccgggtaa ggtgacatga tactgctgcc ggtactgtgc ccaaatcttg
    14461 tcggcatatt ccttgttctg ccgttctatc tcgcacttcc agccccagcc cagccaggca
    14521 tcctggcatt cattgtttcc acaccacaaa gcaatgcagg catgattgcg caaacgtttc
    14581 acattgtcca ccgcctcctg atggatatta tcgagcaggg cgccttctgc cggatacatg
    14641 ctgcaggcaa acataaagtc ctgccaaatc ataattccat gctcatcaca caaatcatag
    14701 aagacatcgt tctcatagat acctccgccc cagacacgca acatattcat gtttacaccg
    14761 gcggcatcga gaatcgtcct tttataattc tcgggagtga cgcgcggcag gaagttatcc
    14821 gaagggatgt aattggctcc tttggcaaaa accggacgcc cgttcagctc tatatagaaa
    14881 gtatgcccgt ccttatccgg ctgatgcacc accttcaaag agcgtatgcc caccctttcg
    14941 gttttagagt ccaacaattc cccgcctgca atgatatccg tacggaaacg gtaaaggaaa
    15001 ggctccccca gtccattact ccaccacagc ttcggcttgt gaaggacgaa atcaacggtc
    15061 acccgattgg tgcctcgctt caaatccgct tgccactcgc caagcactct tccggtagcc
    15121 tcgtctgtta tcgtgaccag cactccgtcc atatccttat cggcatccag ctccacatgt
    15181 ccggcaatca cggccctgcc tgcaccgact tccttctgct cgataaacac atcgttgatt
    15241 ctcaaatcgc tccaagccct gatatacacc ggacgccaga tgccggaggt aaccagacgt
    15301 gggccccagt cccagccata atgataaccc gccttacggg caaaaatgct tatcttcttg
    15361 ttgaacaagc ctccgttttc agactggtca ttggatgccg gatactggta aggaagtgca
    15421 tcccatttgg ggacgtctat ctttaccggc gaatggaagt acaccttcaa tatattattc
    15481 tcctccctga tgtactgcct aacggggata gaccagcggc gaaacatatt gtc
//
