LOCUS gnlProkkaJCNLCHDG_31 25185 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|JCNLCHDG_31. ACCESSION gnlProkkaJCNLCHDG_31 VERSION gnlProkkaJCNLCHDG_31 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2025-04-28 10:03:09 Original ID :: gnl|Prokka|JCNLCHDG_31 NOTE: This is a single region extracted from a larger record! Orig. start :: 0 Orig. end :: 25185 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..25185 /aStool="rule-based-clusters" /category="NRPS" /contig_edge="True" /core_location="[1357:5185]" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" /tool="antismash" proto_core 1358..5185 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" cand_cluster 1..25185 /SMILES="NC(CC(C)C)C(=O)O" /candidate_cluster_number="1" /contig_edge="True" /detection_rules="cds(Condensation and (AMP-binding or A-OX))" /kind="single" /product="NRPS" /protoclusters="1" /tool="antismash" region 1..25185 /candidate_cluster_numbers="1" /contig_edge="True" /product="NRPS" /region_number="1" /rules="cds(Condensation and (AMP-binding or A-OX))" /tool="antismash" aSDomain 2..829 /aSDomain="Epimerization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg15_1_Epimerization.1" /evalue="1.10E-140" /label="ctg15_1_Epimerization.1" /locus_tag="ctg15_1" /protein_end="276" /protein_start="0" /score="461.6" /tool="antismash" /translation="MMLHAKKGFDPERVEKTLQALIEHHDALRMVYREENGDIVQVYKP IGESKVSFEIVDLYGSDEEMLRSQIKLLANKLQSSLDLRNGPLLKAEQYRTEAGDHLLI AVHHLVVDGVSWRILLEDFASGYMQAEKEESLVFPQKTNSFKDWAEELAAFSQSAHLLQ QAEYWSQIAAEQVSPLPKDCETEQRIVKDTSSVLCELTAEDTKHLLTDVHQPYGTEIND ILLSALGLTMKEWTKGAKIGINLEGHGREDIIPNVNISRTVGWFTAQYPVVLDI" aSModule 2..1288 /domains="nrpspksdomains_ctg15_1_Epimerization.1" /domains="nrpspksdomains_ctg15_1_TIGR01720.1" /incomplete /locus_tags="ctg15_1" /tool="antismash" /type="unknown" CDS 2..1321 /NRPS_PKS="Domain: Epimerization (0-276). E-value: 1.1e-140. Score: 461.6. Matches aSDomain: nrpspksdomains_ctg15_1_Epimerization.1" /NRPS_PKS="Domain: TIGR01720 (280-429). E-value: 6.8e-55. Score: 177.0. Matches aSDomain: nrpspksdomains_ctg15_1_TIGR01720.1" /gene_functions="biosynthetic-additional (rule-based-clusters) Condensation" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127:condensation domain-containing protein (Score: 128.4; E-value: 7e-39)" /gene_kind="biosynthetic-additional" /locus_tag="ctg15_1" /sec_met_domain="Condensation (E-value: 2.2e-75, bitscore: 246.9, seeds: 42, tool: rule-based-clusters)" /transl_table=11 /translation="MMLHAKKGFDPERVEKTLQALIEHHDALRMVYREENGDIVQVYKP IGESKVSFEIVDLYGSDEEMLRSQIKLLANKLQSSLDLRNGPLLKAEQYRTEAGDHLLI AVHHLVVDGVSWRILLEDFASGYMQAEKEESLVFPQKTNSFKDWAEELAAFSQSAHLLQ QAEYWSQIAAEQVSPLPKDCETEQRIVKDTSSVLCELTAEDTKHLLTDVHQPYGTEIND ILLSALGLTMKEWTKGAKIGINLEGHGREDIIPNVNISRTVGWFTAQYPVVLDISDADA SAVIKTVKENLRRIPDKGVGYGILRYFTETAETKGFTPEISFNYLGQFDSEVKTDFFEP SAFDMGRQVSGESEALYALSFSGMIRNGRFVLSCSYNEKEFERATVEEQMERFKENLLM LIRHCTEKEDKEFTPSDFSAEDLEMDEMGDIFDMLEENLK" CDS_motif 26..100 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_1_0001" /evalue="1.50E-06" /label="C2_LCL_024-062" /locus_tag="ctg15_1" /protein_end="33" /protein_start="8" /score="20.6" /tool="antismash" /translation="FDPERVEKTLQALIEHHDALRMVYR" CDS_motif 305..370 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_1_0002" /evalue="2.70E-12" /label="NRPS-E2" /locus_tag="ctg15_1" /protein_end="123" /protein_start="101" /score="38.7" /tool="antismash" /translation="LLIAVHHLVVDGVSWRILLEDF" CDS_motif 773..823 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_1_0003" /evalue="1.00E-08" /label="NRPS-E5" /locus_tag="ctg15_1" /protein_end="274" /protein_start="257" /score="27.1" /tool="antismash" /translation="NISRTVGWFTAQYPVVL" aSDomain 842..1288 /aSDomain="TIGR01720" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg15_1_TIGR01720.1" /evalue="6.80E-55" /label="ctg15_1_TIGR01720.1" /locus_tag="ctg15_1" /protein_end="429" /protein_start="280" /score="177.0" /tool="antismash" /translation="ASAVIKTVKENLRRIPDKGVGYGILRYFTETAETKGFTPEISFNY LGQFDSEVKTDFFEPSAFDMGRQVSGESEALYALSFSGMIRNGRFVLSCSYNEKEFERA TVEEQMERFKENLLMLIRHCTEKEDKEFTPSDFSAEDLEMDEMGD" CDS_motif 863..922 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_1_0004" /evalue="6.30E-12" /label="NRPS-E6" /locus_tag="ctg15_1" /protein_end="307" /protein_start="287" /score="37.5" /tool="antismash" /translation="VKENLRRIPDKGVGYGILRY" CDS_motif 956..985 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_1_0005" /evalue="1.10E-03" /label="NRPS-E7" /locus_tag="ctg15_1" /protein_end="328" /protein_start="318" /score="11.3" /tool="antismash" /translation="PEISFNYLGQ" aSDomain 1358..1453 /aSDomain="NRPS-COM_Nterm" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg15_2_NRPS-COM_Nterm.1" /evalue="1.40E-16" /label="ctg15_2_NRPS-COM_Nterm.1" /locus_tag="ctg15_2" /protein_end="32" /protein_start="0" /score="51.3" /tool="antismash" /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQ" CDS 1358..5185 /NRPS_PKS="Domain: NRPS-COM_Nterm (0-32). E-value: 1.4e-16. Score: 51.3. Matches aSDomain: nrpspksdomains_ctg15_2_NRPS-COM_Nterm.1" /NRPS_PKS="Domain: Condensation_DCL (9-308). E-value: 3.7e-119. Score: 389.1. Matches aSDomain: nrpspksdomains_ctg15_2_Condensation_DCL.1" /NRPS_PKS="Domain: AMP-binding (469-867). E-value: 3.6e-112. Score: 366.8. Matches aSDomain: nrpspksdomains_ctg15_2_AMP-binding.1" /NRPS_PKS="Domain: PCP (973-1042). E-value: 1.3e-25. Score: 81.3. Matches aSDomain: nrpspksdomains_ctg15_2_PCP.1" /NRPS_PKS="Domain: Thioesterase (1060-1266). E-value: 3.8e-37. Score: 120.7. Matches aSDomain: nrpspksdomains_ctg15_2_Thioesterase.1" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127:condensation domain-containing protein (Score: 332.5; E-value: 8e-101)" /gene_kind="biosynthetic" /locus_tag="ctg15_2" /sec_met_domain="Condensation (E-value: 1.5e-93, bitscore: 306.5, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 2.5e-122, bitscore: 401.8, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 6.7e-18, bitscore: 58.5, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVKG SLNIKCLEESMNVIMDRYDVFRTVFIHEKVKRPVQVVLKKRQFHIEEIDLTHLTGSEQT AKINEYKEQDKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQDLF KVYNALREQKPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEGFEGQTTFAEQRKKQ KDGYEPKELLFSLSEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLAFGTVV SGRPAEIKGVEHMVGLFINVVPRRVKLSEGITFNGLLKRLQEQSLQSEPHQYVPLYDIQ SQADQPKLIDHIIVFENYPLQDAKNEESSENGFDMVDVHVFEKSNYDLNLMASPGDEML IKLAYNENVFDEAFILRLKSQLLTAIQQLIQNPDQPVSTINLVDDREREFLLTGLNPPA QAHETKPLTYWFKEAVNANPDAPALTYSGQTLSYRELDEEANRIARRLQKHGAGKGSVV ALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLLTHQEMKEQAA ELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNITTHANIQGL VKHVDYMAFSDQDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHTLLDTERLTDLIL QENVNVMFATTALFNLLTDAGEDWMKGLRCILFGGERASVPHVRKALRIMGPGKLINCY GPTEGTVFATAHVVHDLPDSISSLPIGKPISNASVYILNEQSQLQPFGAVGELCISGMG VSKGYVNRADLTKEKFIENPFKPGETLYRTGDLARWLPDGTIEYAGRIDDQVKIRGHRI ELEEIEKQLQEYPGVKDAVVVADRHESGDASINAYLVNRTQLSAEDVKAHLKKQLPAYM VPQTFTFLDELPLTTNGKVNKRLLPKPDQDQLAEEWIGPRNEMEETIAQIWSEVLGRKQ IGIHDDFFALGGHSLKAMTAASRIKKELGIDLPVKLLFEAPTIAGISAYLKNGGSDGLQ DVTIMNQDQEQIIFAFPPVLGYGLMYQNLSSRLPSYKLCAFDFIEEEDRLDRYADLIQK LQPEGPLTLFGYSAGCSLAFEAAKKLEEQGRIVQRIIMVDSYKKQGVSDLDGRTVESDV EALMNVNRDNEALNSEAVKHGLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFDMPE WLASWEEATTGVYRVKRGFGTHAEMLQGETLDRNAEILLEFLNTQTVTVS" aSDomain 1385..2281 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg15_2_Condensation_DCL.1" /domain_subtypes="Condensation_DCL" /evalue="3.70E-119" /label="ctg15_2_Condensation_DCL.1" /locus_tag="ctg15_2" /protein_end="308" /protein_start="9" /score="389.1" /tool="antismash" /translation="QDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVKGSLNIKCLEE SMNVIMDRYDVFRTVFIHEKVKRPVQVVLKKRQFHIEEIDLTHLTGSEQTAKINEYKEQ DKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQDLFKVYNALREQ KPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEGFEGQTTFAEQRKKQKDGYEPKEL LFSLSEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLAFGTVVSGRPAEIKG VEHMVGLFINVVPRRVKL" aSModule 1385..5155 /complete /domains="nrpspksdomains_ctg15_2_Condensation_DCL.1" /domains="nrpspksdomains_ctg15_2_AMP-binding.1" /domains="nrpspksdomains_ctg15_2_PCP.1" /domains="nrpspksdomains_ctg15_2_Thioesterase.1" /final_module /locus_tags="ctg15_2" /monomer_pairings="Leu -> Leu" /tool="antismash" /type="nrps" CDS_motif 1394..1435 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_2_0001" /evalue="3.00E-05" /label="C1_DCL_004-017" /locus_tag="ctg15_2" /protein_end="26" /protein_start="12" /score="15.8" /tool="antismash" /translation="YYLSPMQEGMLFHA" CDS_motif 1457..1573 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_2_0002" /evalue="2.50E-12" /label="C2_DCL_024-062" /locus_tag="ctg15_2" /protein_end="72" /protein_start="33" /score="39.1" /tool="antismash" /translation="FYLEQITMKVKGSLNIKCLEESMNVIMDRYDVFRTVFIH" CDS_motif 1790..1855 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_2_0003" /evalue="1.70E-11" /label="C3_DCL_135-156" /locus_tag="ctg15_2" /protein_end="166" /protein_start="144" /score="36.5" /tool="antismash" /translation="YHHIILDGWCFGIVVQDLFKVY" CDS_motif 1901..1939 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_2_0004" /evalue="5.50E-04" /label="C4_DCL_171-183" /locus_tag="ctg15_2" /protein_end="194" /protein_start="181" /score="12.4" /tool="antismash" /translation="PYKDYIKWLEKQD" CDS_motif 2177..2272 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_2_0005" /evalue="1.30E-18" /label="C5_DCL_263-294" /locus_tag="ctg15_2" /protein_end="305" /protein_start="273" /score="59.4" /tool="antismash" /translation="DLAFGTVVSGRPAEIKGVEHMVGLFINVVPRR" CDS_motif 2321..2434 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_2_0006" /evalue="1.00E-17" /label="C67_DCL_14fromHMM" /locus_tag="ctg15_2" /protein_end="359" /protein_start="321" /score="56.6" /tool="antismash" /translation="QEQSLQSEPHQYVPLYDIQSQADQPKLIDHIIVFENYP" aSDomain 2765..3958 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg15_2_AMP-binding.1" /evalue="3.60E-112" /label="ctg15_2_AMP-binding.1" /locus_tag="ctg15_2" /protein_end="867" /protein_start="469" /score="366.8" /specificity="substrate consensus: Leu" /tool="antismash" /translation="FKEAVNANPDAPALTYSGQTLSYRELDEEANRIARRLQKHGAGKG SVVALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLLTHQEMKE QAAELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNITTHANI QGLVKHVDYMAFSDQDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHTLLDTERLTD LILQENVNVMFATTALFNLLTDAGEDWMKGLRCILFGGERASVPHVRKALRIMGPGKLI NCYGPTEGTVFATAHVVHDLPDSISSLPIGKPISNASVYILNEQSQLQPFGAVGELCIS GMGVSKGYVNRADLTKEKFIENPFKPGETLYRTGDLARWLPDGTIEYAGRIDDQVKIR" CDS_motif 2951..2992 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_2_0007" /evalue="2.60E-05" /label="NRPS-A_a2" /locus_tag="ctg15_2" /protein_end="545" /protein_start="531" /score="17.4" /tool="antismash" /translation="LGVLKAGAAYLPVD" CDS_motif 3185..3244 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_2_0008" /evalue="9.20E-08" /label="NRPS-A_a3" /locus_tag="ctg15_2" /protein_end="629" /protein_start="609" /score="24.4" /tool="antismash" /translation="AYIMYTSGTTGKPKGNITTH" CDS_motif 3752..3841 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_2_0009" /evalue="3.20E-13" /label="NRPS-A_a6" /locus_tag="ctg15_2" /protein_end="828" /protein_start="798" /score="41.8" /tool="antismash" /translation="PFGAVGELCISGMGVSKGYVNRADLTKEKF" CDS_motif 3923..3988 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_2_0010" /evalue="9.60E-12" /label="NRPS-A_a8" /locus_tag="ctg15_2" /protein_end="877" /protein_start="855" /score="36.8" /tool="antismash" /translation="YAGRIDDQVKIRGHRIELEEIE" aSDomain 4277..4483 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg15_2_PCP.1" /evalue="1.30E-25" /label="ctg15_2_PCP.1" /locus_tag="ctg15_2" /protein_end="1042" /protein_start="973" /score="81.3" /tool="antismash" /translation="EETIAQIWSEVLGRKQIGIHDDFFALGGHSLKAMTAASRIKKELG IDLPVKLLFEAPTIAGISAYLKNG" aSDomain 4538..5155 /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg15_2_Thioesterase.1" /evalue="3.80E-37" /label="ctg15_2_Thioesterase.1" /locus_tag="ctg15_2" /protein_end="1266" /protein_start="1060" /score="120.7" /tool="antismash" /translation="IFAFPPVLGYGLMYQNLSSRLPSYKLCAFDFIEEEDRLDRYADLI QKLQPEGPLTLFGYSAGCSLAFEAAKKLEEQGRIVQRIIMVDSYKKQGVSDLDGRTVES DVEALMNVNRDNEALNSEAVKHGLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFDM PEWLASWEEATTGVYRVKRGFGTHAEMLQGETLDRNAEILLEF" CDS_motif 4682..4756 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_2_0011" /evalue="6.30E-10" /label="NRPS-te1" /locus_tag="ctg15_2" /protein_end="1133" /protein_start="1108" /score="31.5" /tool="antismash" /translation="QPEGPLTLFGYSAGCSLAFEAAKKL" CDS 5214..5942 /NRPS_PKS="Domain: Thioesterase (14-231). E-value: 3.7e-55. Score: 179.7. Matches aSDomain: nrpspksdomains_ctg15_3_Thioesterase.1" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (rule-based-clusters) PF00561" /gene_functions="biosynthetic-additional (smcogs) SMCOG1004:thioesterase (Score: 213; E-value: 5.8e-65)" /gene_kind="biosynthetic-additional" /locus_tag="ctg15_3" /sec_met_domain="Abhydrolase_6 (E-value: 4.3e-15, bitscore: 50.3, seeds: 455, tool: rule-based-clusters)" /sec_met_domain="PF00561 (E-value: 1.9e-06, bitscore: 21.1, seeds: 48, tool: rule-based-clusters)" /transl_table=11 /translation="MSQLFKSFDASEKTQLICFPFAGGYSASFRPLHAFLQGECEMLAA EPPGHGTNQTSAIEDLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGI FPQAVIISAIQPPHIQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSD YRALEQFELYDLAQIQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQ TEEVAERIFAILNQHPIIQP" aSDomain 5256..5906 /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg15_3_Thioesterase.1" /evalue="3.70E-55" /label="ctg15_3_Thioesterase.1" /locus_tag="ctg15_3" /protein_end="231" /protein_start="14" /score="179.7" /tool="antismash" /translation="QLICFPFAGGYSASFRPLHAFLQGECEMLAAEPPGHGTNQTSAIE DLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGIFPQAVIISAIQPPH IQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSDYRALEQFELYDLAQ IQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQTEEVAERIF" CDS_motif 5439..5510 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg15_3_0001" /evalue="1.90E-08" /label="NRPS-te1" /locus_tag="ctg15_3" /protein_end="99" /protein_start="75" /score="26.7" /tool="antismash" /translation="PDRPFVLFGHSMGGMITFRLAQKL" CDS 6043..7269 /gene_functions="transport (smcogs) SMCOG1137:Major facilitator superfamily MFS 1 (Score: 339.3; E-value: 4.1e-103)" /gene_kind="transport" /locus_tag="ctg15_4" /transl_table=11 /translation="MRTSPRMKWFVLLFTFVFAIGMNSFRNSFQFFMLPMADAFHADRS LISVSVSIFMITTGIVQFFVGFFIDRFSVRKIMALGAVCISASFLVLPYSPNVHVFSAI YGVLGGIGYSCAVGVTTQYFISCWFDTHKGLALAILTNANSAGLLLLSPIWAAAPYHAG WQSTYTILGIVMAAVLLPLLVFGMKHPPHAQAETVKKSYDWRGFWNVMKQSRLIHILYF GVFTCGFTMGIIDAHLVPILKDAHVSHVNGMMAAFGAFIIIGGLLAGWLSDLLGSRSVM LSILFFIRLLSLICLLIPILGIHHSDLWYFGFILLFGLSYTGVIPLTAASISESYQTGL IGSLLGINFFIHQVAGALSVYAGGLFFDMTHGYLLIVAVCIVFVGLSAVIELVPFLDKQ KAKETHHSI" CDS complement(7284..7841) /locus_tag="ctg15_5" /transl_table=11 /translation="MIQYASESINLPGEITFKDVREIFFYQIAKISCFYFLLFCAIFAA VNFINGWPRIVYGSDALNLFMNSMLIIVMSVLFTLLLLLLLYVKFSRAYKKNERMKSKR TYTLNQEGIRICSKKYDLIFNWDEITAVFEYKNIFRVNTSSGQYIAIPKHFFHSEEEMN RFKEIILKNTETKKLKFKKDQH" CDS complement(7895..8833) /gene_functions="transport (smcogs) SMCOG1166:transporter, EamA family (Score: 156.9; E-value: 1.2e-47)" /gene_kind="transport" /locus_tag="ctg15_6" /transl_table=11 /translation="MVKHQQTPAYIAAILYSFIIGLSFLFVKIALQTAEPFDILAHRFT IAFAAATVPILFGWVKLSIRVKDVIDILPLALLYPALFFSFQAFGLVYSSSSEAGIIQA AIPIFTMVFAAYVLKERPTWTQKGFTVLSVAGVMFIFVMKGVDVESASLKGSLLILLSA LSSAMYNTAARKMTQRFKLTELTYIMSAIGFVVFNAIALVRHGAAGTVGTYFLPFREPG FVLAIVYLGVLSSLVTSFLSNYTLSRIEAFKMSAFNHVSTIVTMIAGFVILNESLAWYH LAGAVCIMIGVVGSNINLEKKTKRPGMPAKK" CDS 8957..10291 /NRPS_PKS="Domain: Aminotran_1_2 (96-438). E-value: 4.2e-23. Score: 73.9. Matches aSDomain: nrpspksdomains_ctg15_7_Aminotran_1_2.1" /gene_functions="biosynthetic-additional (rule-based-clusters) Aminotran_1_2" /gene_functions="biosynthetic-additional (smcogs) SMCOG1019:aminotransferase (Score: 264.9; E-value: 2e-80)" /gene_kind="biosynthetic-additional" /locus_tag="ctg15_7" /sec_met_domain="Aminotran_1_2 (E-value: 1.3e-22, bitscore: 73.8, seeds: 48, tool: rule-based-clusters)" /transl_table=11 /translation="MEKYMSLLTRIEEMMQSTSYQEGDRLPSIRQLSARYQVSKSTVIR ALQELEKRHLIYSVPKSGYYIVKKSGKSKSGQPGPIDFATSAPDPDVFPYLDFQHCINK AIDTYKNDLFIYGTPKGLPSLIRVLRKLLATQQVFADERHIFITSGVQQALSLLCAMPF PNGKEKIAIEQPGYHLMVEQLETLGIPAIGVKRTEEGLDIAKVERLFQTESIKFFYTMP RFHNPLGCSLSERDKQELVRLAEAYDVYLVEDDYLGDLEENKKADPLYAYDLSSHVIYL KSFSKMMFPGLRVGAAVLPEALTDTFYAYKKLNDIDCSMISQAALEIYLKSGMYGRHKE KIRDSYKERSLRLHQAIRTHRQLGSGRFTFSSGQAPCMHTHLVLPQDLPASRVIHRLEK QGVLLEAIDRHYLSDYPKENLLKINISNVKTEDIERGVKLLMSHL" aSDomain 9245..10270 /aSDomain="Aminotran_1_2" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg15_7_Aminotran_1_2.1" /evalue="4.20E-23" /label="ctg15_7_Aminotran_1_2.1" /locus_tag="ctg15_7" /protein_end="438" /protein_start="96" /score="73.9" /tool="antismash" /translation="DFQHCINKAIDTYKNDLFIYGTPKGLPSLIRVLRKLLATQQVFAD ERHIFITSGVQQALSLLCAMPFPNGKEKIAIEQPGYHLMVEQLETLGIPAIGVKRTEEG LDIAKVERLFQTESIKFFYTMPRFHNPLGCSLSERDKQELVRLAEAYDVYLVEDDYLGD LEENKKADPLYAYDLSSHVIYLKSFSKMMFPGLRVGAAVLPEALTDTFYAYKKLNDIDC SMISQAALEIYLKSGMYGRHKEKIRDSYKERSLRLHQAIRTHRQLGSGRFTFSSGQAPC MHTHLVLPQDLPASRVIHRLEKQGVLLEAIDRHYLSDYPKENLLKINISNVKTEDIERG VK" CDS complement(10464..10961) /NRPS_PKS="Domain: ACPS (103-155). E-value: 4.7e-18. Score: 57.2. Matches aSDomain: nrpspksdomains_ctg15_8_ACPS.1" /gene_functions="biosynthetic-additional (smcogs) SMCOG1012:4'-phosphopantetheinyl transferase (Score: 150; E-value: 1e-45)" /gene_kind="biosynthetic-additional" /locus_tag="ctg15_8" /transl_table=11 /translation="MKIYGIYMDRPLSQEENERFMSFISPEKREKCRRFYHKEDAHRTL LGDVLVRSVISRQYQLDKSDIRFSTQEYGKPCIPDLPDAHFNISHSGRWVICAFDSQPI GIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWSMKESFIKQGRQRLIA SA" aSDomain complement(10497..10652) /aSDomain="ACPS" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg15_8_ACPS.1" /evalue="4.70E-18" /label="ctg15_8_ACPS.1" /locus_tag="ctg15_8" /protein_end="155" /protein_start="103" /score="57.2" /tool="antismash" /translation="IGIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWS MKESFIK" CDS complement(11066..11713) /locus_tag="ctg15_9" /transl_table=11 /translation="MKQELVLRWTFYFAGLIILAFGVSLTIEGKALGISPWDAFHYSLF QHFGLTVGQWSIIIGALIVGFTSLFTRAWPKIGALLNMVLIGVFIDFFNFILPALSTYT GSIIVFSLGVVLIGYGVGVYVSAGLGAGPRDSLMMLITEKTGWNVQWVRNGMELTILFA AWGMGGPIGFGTILTAILTGLILRFSLPQSIQLLNYAVARRTAAVKASPPVH" CDS complement(12034..12777) /gene_functions="transport (smcogs) SMCOG1000:ABC transporter ATP-binding protein (Score: 222.5; E-value: 1e-67)" /gene_kind="transport" /locus_tag="ctg15_10" /transl_table=11 /translation="MLTVKGLNKSFGENEILKKIDMKIEKGKVIAILGPSGSGKTTLLR CLNALEIPNRGELAFDDFSIDFSKKVKQADILKLRRKSGMVFQAYHLFPHRTALENVME GPVQVQKRNKEEVRKEAIQLLDKVGLKDKMDLYPFQLSGGQQQRVGIARALAIQPELML FDEPTSALDPELVGEVLKVIKDLANEGWTMVVVTHEIKFAQEVADEVIFIDGGVIVEQG PPEQIFSAPKEERTQRFLNRILNPL" CDS complement(12791..13495) /gene_functions="transport (smcogs) SMCOG1096:polar amino acid ABC transporter, inner membrane (Score: 244.4; E-value: 1.7e-74)" /gene_kind="transport" /locus_tag="ctg15_11" /transl_table=11 /translation="MFLNNLPALTLGTAIPWDLVQQSFWPILSGGIYYTIPLTILSFIF GMILALITALARMSKVRPLRWVFSVYVSAIRGTPLLVQLFIIFYLFPAFNVTLDPFPSA VIAFSLNVGAYASEIIRASILSVPKGQWEAGYTIGMTHQKTLFRVILPQAFRVSIPPLS NTFISLIKDTSLASQILVAELFRKAQEIGARNLDQILVIYIEAAFIYWIICFLLSLVQH VIERRLDRYVAK" CDS complement(13482..14288) /gene_functions="biosynthetic-additional (smcogs) SMCOG1091:glutamine-binding lipoprotein glnH (Score: 234.7; E-value: 1.6e-71)" /gene_kind="biosynthetic-additional" /locus_tag="ctg15_12" /transl_table=11 /translation="MKKALLALFMVVSIAALAACGAGNDNQSKDNAKDGDLWASIKKKG VLTVGTEGTYEPFTYHDKDTDKLTGYDVEVITEVAKRLGLKVDFKETQWDSMFAGLNSK RFDVVANQVGKTDREDKYDFSDKYTTSRAVVVTKKDNNDIKSEADVKGKTSAQSLTSNY NKLATNAGAKVEGVEGMAQALQMIQQGRVDMTYNDKLAVLNYLKTSGNKNVKIAFETGE PQSTYFTFRKGSGEVVDQVNKALKEMKEDGTLSKISKKWFGEDVSK" CDS complement(14404..15276) /gene_functions="regulatory (smcogs) SMCOG1014:LysR family transcriptional regulator (Score: 244.1; E-value: 2.9e-74)" /gene_kind="regulatory" /locus_tag="ctg15_13" /transl_table=11 /translation="MDIRQLRYFITIAQEQKITSAAKKLHMAQPPLSRQLKQLEDELGV VLFDRNKKKQMTLTYEGAVFLKRAKEILHRFEDAVIEVQELKEEVAGTLAVGSTIYCAA LMLEKVTQIKERYPHLTFNIWENEPATLLELLESRQIDAAVTTTLIKSDTVQFKQLDDI PCVLVLSDEAGYPCGDTIKMVDIPSFPLILLRPVNGKGVYNQVMNEFHRLNLEPRIVCE CHDSATLLSLVSSGFGASILPVTMIPVHMRNHVHTVHIENNPFIMTPAVMWRTDSYLPK PAQQFLDLF" CDS 15366..15980 /gene_functions="biosynthetic-additional (rule-based-clusters) Flavoprotein" /gene_kind="biosynthetic-additional" /locus_tag="ctg15_14" /sec_met_domain="Flavoprotein (E-value: 1.3e-32, bitscore: 105.9, seeds: 143, tool: rule-based-clusters)" /transl_table=11 /translation="MKAEFKRKGGGKVKLVVGMTGATGAIFGVRLLQWLKAAGVETHLV VSPWANVTIKHETGYTLQEVEQLATYTYSHKDQAAAISSGSFDTDGMIVAPCSMKSLAS IRTGMADNLLTRAADVMLKERKKLVLLTRETPLNQIHLENMLALTKMGTIILPPMPAFY NRPRSLEEMVDHIVFRTLDQFGIRLPEAKRWNGIEKQKGGA" CDS 15983..17404 /locus_tag="ctg15_15" /transl_table=11 /translation="MAYQDFREFLAALEKEGQLLTVNEEVKPEPDLGASARAASNLGDK SPALLFNNIYGYHNARIAMNVIGSWPNHAMMLGMPKDTPVKEQFFEFAKRYDQFPMPVK REETAPFHENEITEDINLFDILPLFRINQGDGGYYLDKACVISRDLEDPDNFGKQNVGI YRMQVKGKDRLGIQPVPQHDIAIHLRQAEERGINLPVTIALGCEPVITTAASTPLLYDQ SEYEMAGAIQGEPYRIVKSKLSDLDVPWGAEVVLEGEIIAGEREYEGPFGEFTGHYSGG RSMPIIKIKRVYHRNNPIFEHLYLGMPWTECDYMIGINTCVPLYQQLKEAYPNEIVAVN AMYTHGLIAIVSTKTRYGGFAKAVGMRALTTPHGLGYCKMVIVVDEDVDPFNLPQVMWA LSTKMHPKHDAVIIPDLSVLPLDPGSNPSGITHKMILDATTPVAPETRGHYSQPLDSPL TTKEWEQKLMDLMNK" CDS 17421..17648 /locus_tag="ctg15_16" /transl_table=11 /translation="MHTCPRCDSKKGEVMSKSPVEGAWEVYQCQTCFFTWRSCEPESIT NPEKYNPAFKIDPKETETAIEVPAVPERKA" CDS 17645..18109 /locus_tag="ctg15_17" /transl_table=11 /translation="MIRVNCMSDRLFELLDGSCLNEKQHEAFVLQTVSEDGWPHAAMIS AGEIIALSRTDIRIALWKNTMTSANILRTGKAQFTAWWKGAAYYVKLECAPLPPLKDAE YERDRFSCRIVSVKEDVAKYADLTSGVRIQLHSPEEVLSRWKKTLEDLKR" CDS 18176..19021 /gene_functions="biosynthetic-additional (rule-based-clusters) PF00561" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (smcogs) SMCOG1036:alpha/beta hydrolase fold protein (Score: 63.5; E-value: 4.1e-19)" /gene_kind="biosynthetic-additional" /locus_tag="ctg15_18" /sec_met_domain="PF00561 (E-value: 2e-15, bitscore: 50.5, seeds: 48, tool: rule-based-clusters)" /sec_met_domain="Abhydrolase_6 (E-value: 3.5e-09, bitscore: 31.0, seeds: 455, tool: rule-based-clusters)" /transl_table=11 /translation="MERAGICHSDGFDLAYRIEGEGAPILVIGSAVYYPRLFSSDIKQK YQWVFVDHRGFAKPKRELRAEDSRLDAVLADIERMRTFLQLEDVTILGHSGHAFMALEY ARTYPKQVRKVALFNTAPDNSEERQRKSESFFMETASLERKKRFEKDIENLPQDIDKDP ERRFVHMCIRAEAKSFYQERPHAAALWDGVFTNMPIIDELWGNTFARIDLLQRLADVRM PVYIGLGRYDYLVAPVSLWDAVDGLYPHVDKVIFEKSGHQPMLEEPEAFDQSFRKWLDQ " CDS complement(19061..20539) /gene_functions="transport (smcogs) SMCOG1202:major facilitator transporter (Score: 53.5; E-value: 2.3e-16)" /gene_kind="transport" /locus_tag="ctg15_19" /transl_table=11 /translation="MASIDNESIIKSVPQKGFFGHPRGLFTLFFTEFWERFSYYGMRAI LLYYLYTETVNGGLGFDKGTAVAIMSIYGSLVYMSTIIGGWLADRVFGTANTVFYGGIF IMFGHIALAYPGSSIAFYISMVLIIVGTGLLKPNVSSVVGDLYTKEDPRRDSGFSIFYM GINLGGLLAPLIVGTLGQKYNYHLGFGAAAVGMLLGLIVFALTRKKNLGLAGSNVPNPL SKKSAIGTGIGVIIVAIAVIISVQTGVLTIKRFIDLVSILGILIPVIYFIIMFTSKKAD KTEKSRLAAYVPLFIGAVMFWAIQEQGATILAVYADERIRLSLGGFELQSSWFQSLNPL FVVIFAPIFAWLWMKLGKRQPSTPVKFSIGIILAGLSFIIMVFPAMQGKEALVSPLWLV LSFLLVVLGELCLSPVGLSVTTKLAPAAFSAQTMSMWFLTNAAAQAINAQVAGLFDKIP ETMYFGTIGLISIVLGGILLLLSPVIKRAMKGVL" CDS 20819..22573 /locus_tag="ctg15_20" /transl_table=11 /translation="MAEFILNAADFGVPRDGKTDSTERINQCLSTAVSKGYHTVWFPKG TYLIDATLGGDLNQRFRNAGIIVPGNLEIMMDPECIMKVIPNSSWGYSAFYVGKQENIT ISGGQIIGERDEHTYASAGIRSTHEWGFGICIEGCSNVVIDDVKISDFTGDGIIVSPRG LKTNQDYRTSEQIIIRRCEVRRSRRNNISITGCDMVTVEECLIEDAGTGNGTAPKFGID IEGYGEGDVDYEEPINVSIRNNHFVGNVSSSVTNFNGYGILIEGNHSDNTISYGYGTQT VIKGNILRRPEDAAAAPRVGITGLGVSQGKETSDAVIAGNLITGFSTGIDVRGKSVLVT NNKISNFENTGILVYQSSDVKVDGNQIQNGLSETRRSIGLRAVLSDDIAFLNNCLIQVV DGVNVSGGNMIIKDNLLRKFSRGIWIAQGNAVIEGNTLNPDAFEAVPESYSVSVTNNAG AIIKNNTFKEFKNYPIYCSTSAKTSIIGNHLERSPLLVTIYISAGVHEIFDNTISVNRT AGNPIVIYLNGSAGSIISGNTINNLSAGTATAIQTNTSTNSKIIGNRIFKGTINKHSSD TIDGNMIV" CDS complement(22589..22810) /locus_tag="ctg15_21" /transl_table=11 /translation="MKILGVTGFILICLLAISVLMDMLQGFSLTKAVYNNMSSFKMTTF AEWVVLLFFVLVLVREMYVIYKSKKKNP" CDS 22936..24570 /locus_tag="ctg15_22" /transl_table=11 /translation="MPLFSKRKNNTDSKDKQNTDERNQEQQQEKERPVLISPSLAKNIA ETKKEVGSSSDVIIREIKIGEQDHVHLAVIYISGLVDNNTIHESLIDPLVQDESIQNTH AIQQILEKTLPLGGVKAEKSWDKLFSELMLGNALIFADGHDEALICSTQGGEQRSIQEP STQVSFRGPRQGFTESLQTNISMIRRYIKNPNLWVEKMKKGSVTNTDIALMYIQGICDE KVLKEVKQRLEKIDIDSILESGYIEQLIEDETFTTFPTMYHTERPDVVAGNLLEGRFAI IVDGTPFVLIAPALFVQFFQSVEDYYSRFDIATSIRILRVLVFFISLVAPAVYVAATTF HQEMIPTQLLVVIAAQREIVPFPAVVEALTMEVAFEILREAGVRLPRVVGSAVSIVGAL VIGQAAVQAGIVSPAMVIIVALTAIASFATPAFAMAISARLIRFIFIIASAVMGFYGLI LGIIMMFVHLCSLRSFGVPYMSPLAPFSSQGVKDALFRVPWWADEKRPESVSKEDKVRQ GKDQRPEPAASRGMVNKDLEEGDQNGT" ORIGIN 1 ggtgatgctt cacgccaaaa agggctttga tcctgaacgg gtggagaaaa cattgcaggc 61 gctgatcgag catcatgacg cgctccgcat ggtctaccgc gaggaaaacg gggacatcgt 121 tcaggtgtat aaaccgatcg gtgagagcaa ggtcagcttc gaaatcgtgg atctgtacgg 181 ctccgatgaa gagatgctga gaagccagat taagcttctc gcgaacaagc tgcaaagcag 241 tctcgatctg cgaaacgggc cgcttttaaa ggcggagcaa tatcgcacag aagctgggga 301 tcacctgctc attgctgtac accatctcgt ggtcgacggt gtgtcatggc ggattttgct 361 tgaagacttt gcttcaggct acatgcaggc tgagaaagaa gagagccttg tcttcccgca 421 aaaaacaaac tccttcaagg attgggcgga agaactggcg gcattcagcc aatcagcgca 481 tcttttacag caggctgaat actggtcgca aattgccgct gaacaggttt ctcctttacc 541 taaggattgt gaaacagagc agcggatcgt caaggataca tcatctgtcc tatgtgaatt 601 aacggcagaa gacactaagc atcttttaac agatgttcat cagccatatg gaactgaaat 661 caacgatatt cttctcagcg cgctcggttt gacaatgaaa gaatggacaa agggggccaa 721 aattggcatt aaccttgagg gacacggccg ggaggacatt atcccgaatg tgaatatctc 781 cagaacggtc ggctggttta cggcacaata ccctgttgtg ctcgacatat ctgacgcaga 841 tgcctcagct gtgatcaaaa cagtcaaaga aaacctgcgc cgcattccgg acaaaggtgt 901 tggctacggc attcttcgtt atttcacaga aacagcggaa acaaagggct tcacaccgga 961 gatcagcttc aactatttgg gccaattcga cagtgaagtc aaaaccgatt tctttgaacc 1021 gtccgctttc gatatggggc gccaagtaag cggagaatca gaggcgctgt acgcattaag 1081 cttcagcggc atgatcagaa acggccggtt tgtgctttcc tgctcctaca atgagaagga 1141 gtttgaaaga gctacagtcg aggagcaaat ggaacggttt aaagaaaacc tcctgatgct 1201 aatccgccat tgcacggaaa aagaagacaa ggaattcaca ccaagcgact tcagcgccga 1261 agaccttgaa atggacgaga tgggagatat ctttgacatg cttgaggaga atttaaaata 1321 aaacgcaagg gaattacaga aggcgggagc gaaacatatg agtcaattta gcaaggatca 1381 ggttcaagat atgtattacc tatcgccgat gcaggaaggg atgctttttc atgccatcct 1441 gaatcccggc caaagctttt accttgaaca aatcacgatg aaagtaaaag gcagcttgaa 1501 tatcaaatgt cttgaagaaa gcatgaatgt gatcatggac cggtacgatg tatttcgtac 1561 cgtgttcatt cacgaaaaag taaaaaggcc tgtccaagtc gtattgaaaa aacggcagtt 1621 ccatatagaa gaaatcgatc tgacacactt aacgggcagc gagcaaacag ccaaaatcaa 1681 tgagtacaaa gaacaggata agatcagggg ttttgatttg acgcgggata ttccgatgcg 1741 ggcagccatt ttcaagaaag ctgaagaaag ctttgaatgg gtgtggagct accaccacat 1801 tattttggac ggatggtgct tcggcatcgt cgtacaggat ctatttaagg tatacaatgc 1861 tctgcgcgaa caaaagccgt acagcctgcc gcccgtcaaa ccgtataaag actacatcaa 1921 gtggcttgaa aagcaggata aacaagcatc actgcgttac tggcgcgaat atttagaggg 1981 ctttgaagga caaacgacgt ttgcggagca aagaaagaaa caaaaggacg gctatgagcc 2041 gaaagagctg ctcttttcac tgtcggaggc ggaaacaaag gcctttaccg agcttgcaaa 2101 atcgcagcat accactttga gtacggcgct gcaggcagtc tggagcgtat tgatcagccg 2161 ctatcagcag tctggcgatt tggccttcgg tacagttgtt tcagggcgtc ccgcggaaat 2221 caaaggcgtt gaacatatgg tcgggctgtt tatcaacgtt gtcccgagac gtgtgaagct 2281 gtctgagggt atcacattta acggcttgct caagcggctg caggagcaat cgctgcagtc 2341 cgagccgcat caatatgtgc cgctttatga catccaaagc caggccgatc agccgaaact 2401 gattgaccac atcattgttt ttgagaacta tccgcttcag gatgcgaaaa atgaagaaag 2461 cagtgaaaac ggctttgata tggtggatgt tcatgttttt gagaagtcga attatgatct 2521 caacctgatg gcttccccgg gagatgagat gctgattaag cttgcctata atgagaatgt 2581 gtttgatgag gcgtttatcc tgcgcttgaa atctcagctt cttacagcaa ttcagcagct 2641 catccagaat cctgatcagc ctgtcagcac gatcaacctc gttgacgaca gggagagaga 2701 atttttgcta accggcttaa acccgccggc tcaagctcat gaaacaaagc ctctgacgta 2761 ttggttcaag gaagcagtga acgccaatcc ggatgcaccg gcgcttacgt attccggcca 2821 gaccctgtct tatcgcgaat tagatgagga agcgaaccgc attgcacgcc ggctgcaaaa 2881 acacggtgcg ggcaaaggct ctgttgtagc gctgtacacg aagcgctcac ttgaactggt 2941 gatcggcatt ctcggtgtat taaaggcggg agcagcctat ctgccggttg atccgaagct 3001 gccagaggac cgaatctcgt atatgctggc tgacagtgcg gcagcctgtc ttctgacgca 3061 tcaggagatg aaagaacaag cggctgagct gccgtataca ggcacaacgc tcttcattga 3121 tgatcaaaca cggtttgaag aacaggcaag cgatcctgca accgcgattg atcctaatga 3181 tccggcatat atcatgtaca cgtccggcac aaccggaaag ccaaagggca atatcaccac 3241 tcatgccaat attcaaggat tggtcaagca tgtagactac atggcatttt ctgatcagga 3301 tacgttcttg tctgtttcga attacgcctt tgatgcattt acctttgatt tctatgcttc 3361 tatgctgaat gcggcacggc tcattatcgc agatgaacat acgctgcttg atacagaacg 3421 gctcacagat ctgatcctgc aagagaatgt caatgtcatg tttgcgacaa ccgcactatt 3481 taatcttctc acagatgcgg gagaggattg gatgaagggg cttcgctgta tattattcgg 3541 cggagagcgc gcgtcagtgc ctcatgtcag aaaagcgctg cggatcatgg ggccgggcaa 3601 gctgattaac tgctacgggc cgactgaggg aacagtgttt gcgacagctc acgtcgtgca 3661 tgatctgccg gattccatct cctcattgcc gatcggaaag ccgatcagca atgccagtgt 3721 ttatattctg aatgagcaaa gccagctcca gccattcggg gcggtcggtg aactgtgcat 3781 cagcggaatg ggcgtgtcaa aagggtatgt aaatcgtgct gacctcacga aggaaaagtt 3841 tatcgagaac ccgttcaagc cgggagaaac gctttaccgt acaggggatt tagcgcgctg 3901 gctgccggat ggaacgattg aatacgccgg ccgtattgac gaccaggtca aaatacgcgg 3961 acaccggatt gagcttgaag aaatcgaaaa gcagctgcag gaatacccag gtgtgaaaga 4021 tgcggtcgtt gtggcggacc gccatgagtc tggcgatgca tcaatcaatg cctaccttgt 4081 gaaccgaacg cagctttcag ctgaagacgt gaaggcgcac ctgaaaaaac agcttcctgc 4141 ttacatggtg ccgcaaacct ttaccttctt ggatgagctt cctttaacga cgaacgggaa 4201 agtcaataaa cggctgctcc caaaacctga tcaggatcag ctggcggaag aatggattgg 4261 accgcggaac gagatggaag aaacaatcgc acaaatatgg tctgaggttc tcggcagaaa 4321 gcaaattggc attcatgacg atttctttgc gctcggaggg cattccttga aggccatgac 4381 cgccgcgtcc cgcatcaaga aagagctcgg gattgatctt ccagtgaagc ttttgtttga 4441 agcgccgacg atcgccggca tttcagcgta tttgaaaaac gggggctctg atggcttgca 4501 ggatgtaacg ataatgaatc aggatcagga gcagatcatt ttcgcatttc cgccggttct 4561 gggctatggc cttatgtacc aaaatctgtc cagccgcttg ccgtcataca agctatgcgc 4621 ctttgatttt attgaggagg aagaccggct tgaccgctat gcggatttga tccagaagct 4681 gcagccggaa gggcctttaa cattgtttgg atattcagcg ggatgcagcc tggcgtttga 4741 agctgcgaaa aagcttgagg aacaaggccg tattgttcag cggatcatca tggtggattc 4801 ctataaaaaa caaggtgtca gtgatctgga cggacgcacg gttgaaagtg atgtcgaagc 4861 gttgatgaat gtcaatcggg acaatgaagc gctcaacagc gaagccgtca aacacggcct 4921 caagcaaaaa acacatgcct tttactcata ctacgtcaac ctgatcagca caggccaggt 4981 gaaagcagat attgatctgt tgacttccgg cgctgatttt gacatgccgg aatggcttgc 5041 atcatgggaa gaagctacaa caggtgttta ccgtgtgaaa agaggcttcg gaacacacgc 5101 agaaatgctg cagggcgaaa cgctagatag gaatgcggag attttgctcg aatttcttaa 5161 tacacaaacc gtaacggttt cataaatgaa gtgatgaaag gaggagacag ccaatgagcc 5221 aactcttcaa atcatttgat gcgtcggaaa aaacacagct catctgtttt ccgtttgccg 5281 gcggctattc ggcgtcgttt cgccctctcc atgctttttt gcagggggag tgcgagatgc 5341 tcgctgccga gccgccggga cacggcacga atcaaacgtc agccattgag gatctcgaag 5401 agctgacgga tttgtacaag caagaactga accttcgccc tgatcggccg tttgtgctgt 5461 tcggacacag tatgggcgga atgatcacct tcaggctggc gcaaaagctt gagcgtgaag 5521 gcatctttcc gcaggcggtt atcatttctg caatccagcc gcctcatatt cagcggaaga 5581 aagtgtccca cctgcctgat gatcagtttc tcgatcatat tatccaatta ggcggaatgc 5641 ccgcagagct tgttgaaaat aaggaggtca tgtccttttt cctgccttct ttccgatcag 5701 attaccgggc tcttgaacaa tttgagcttt acgatctggc ccagatccag tcgcctgttc 5761 atgtctttaa cgggcttgat gataaaaaat gcatacgaga tgcggaaggg tggaagaagt 5821 gggcaaaaga catcacattc catcaatttg acggcgggca catgttcctg ctgtcacaaa 5881 cggaagaagt cgcagaacgg atttttgcga tcttgaatca gcatccgatc attcaaccgt 5941 gatcaaaagc ggacagcttc ggctgttccg ctttttttgt gttgaatgcc aatttctgca 6001 tggtataata gtcgaaatac tcaaataaag gcaggtcgaa acatgcgcac gtctcccagg 6061 atgaaatggt ttgtattgct gtttacgttt gttttcgcca tcggaatgaa ctcattcaga 6121 aattcctttc aattttttat gctgccaatg gcagacgcct tccatgccga caggtcgctg 6181 atttcggttt ctgtcagcat ttttatgatc acaaccggca tcgtccagtt ttttgtcggt 6241 ttttttatcg accgtttcag tgtcagaaaa attatggcgc tgggagctgt ttgcatcagc 6301 gcaagctttt tggtgcttcc ttattcaccg aatgttcatg tgttttccgc catttacggt 6361 gtgcttggcg gaatcgggta ttcctgcgcg gtcggcgtga cgacccagta tttcatcagc 6421 tgttggtttg acacacacaa aggtctggcg cttgctattt tgaccaatgc caactctgcg 6481 ggcctgctgc ttctctcgcc catttgggct gcggctccgt atcatgccgg ctggcagagc 6541 acctatacca ttttgggaat cgtcatggcg gctgttctgc tgccgctcct cgtctttggg 6601 atgaagcacc cgccacatgc gcaagcggaa actgtgaaaa aatcttatga ttggcgaggg 6661 ttttggaacg tgatgaagca atcccgcctc attcatatcc tgtacttcgg cgtgtttact 6721 tgcggattta caatgggaat tattgatgct cacctcgtcc cgatactgaa ggatgcgcat 6781 gtctctcatg tcaacggaat gatggccgcg ttcggggcat ttatcatcat tggcggatta 6841 ttggcgggct ggctgtcaga tctcctcggc agcagaagcg tcatgctatc catcttattt 6901 ttcattcggc tgctcagcct catttgcctg ctcattccca ttctcggaat tcatcacagc 6961 gacctttggt acttcgggtt tatcctgtta ttcgggctca gttacacagg cgtgatcccg 7021 ctgaccgcgg cgtcaatttc ggaaagctat caaacaggat tgatcggatc gctgttaggc 7081 atcaatttct ttatccatca ggttgccgga gctctcagcg tgtatgcggg cggtttgttt 7141 tttgacatga ctcatggtta tttactgatt gtcgctgtgt gcatcgtgtt tgtgggttta 7201 tcggctgtaa tagagctggt gccgttttta gataaacaga aggcaaaaga aacccaccat 7261 tcaatataaa aggatcagca ctgtcaatgc tgatcctttt taaatttgag tttttttgtt 7321 tcggtatttt taaggataat ctccttgaat ctgttcatct cctcttcgga gtgaaaaaaa 7381 tgtttgggga tcgcaatata ttggccactt gatgtattga ccctgaagat atttttatat 7441 tcgaaaacag ctgtaatttc atcccaattg aaaatgaggt catatttttt agaacatata 7501 cgaattcctt cttggttcag agtatatgtt cttttggatt tcatccgttc gttcttcttg 7561 tatgctctgg aaaacttcac atatagaaga aggaggagca gcagtgtaaa cagaacggac 7621 atcacgataa tcaacatact gttcataaac aagttaagcg cgtcacttcc ataaacgata 7681 cggggccatc cgttaatgaa gttaactgca gcaaatatgg cgcaaaacaa tagaaagtaa 7741 aagcatgata tttttgcgat ttgataaaaa aagatttctc ttacatcctt aaaagtgatt 7801 tctcctggaa gattgatact ttcactagca tattgaatca tacggtaaac ctacacctct 7861 aaccatgttt ttccttttag tctagcataa tttctcattt ttttgcaggc ataccagggc 7921 gctttgtttt tttctccaga ttgatattgc tccccaccac gccaatcata atacaaacag 7981 ccccggcaag atgataccag gccaggcttt cgttgagaat cacaaatcct gcaatcatcg 8041 tcacaatggt agatacatga ttaaaagcgc tcattttaaa cgcctcaatt cgcgacagcg 8101 tatagttaga cagaaatgaa gtgacaagtg aagacagcac gcccaaatac acaatggcga 8161 gaacgaagcc gggctcccgg aacggcagaa aataagtgcc gactgttccc gccgctccgt 8221 gacgcacaag ggcgatggcg ttgaagacga caaagccgat ggctgacatg atgtaggtga 8281 gctcggtcag cttgaaccgc tgcgtcattt ttctggcagc agtattgtac atcgctgaag 8341 acaaagcgga caataggatc agcaaagacc cttttaagct ggctgattcc acgtcaacgc 8401 ctttcatcac aaaaataaac atgacgccgg caacggataa aaccgtgaac cccttttgcg 8461 tccacgttgg gcgttccttt aaaacataag cggcaaagac catcgtgaaa atcggaatgg 8521 ctgcctgaat aattcccgct tcagaggagg acgagtacac aaggccgaat gcctgaaagc 8581 tgaaaaataa cgcgggatac agcagggcga gcggcaaaat gtcaatgacg tcctttacgc 8641 ggattgatag ctttacccag ccgaataaga tcggtacagt ggccgcagca aacgcaatgg 8701 tgaaccgatg cgccaaaata tcaaacggct ctgctgtttg cagtgcgatt tttacgaata 8761 gaaaggataa accgataatg aacgaatata aaatagccgc tatataagcg ggggtttgct 8821 gatgtttaac cataatggga agggctcctt tacctgaatt gcagcgccgg tcgctccctt 8881 tattgtatgg ccgcggtcag aacggtacaa tgagaaaaac aatgaactgt accggtacaa 8941 aacaggggga gaaggcatgg agaaatatat gagtctatta acgaggatag aggagatgat 9001 gcaaagcacc tcatatcaag aaggagacag gcttccatct atccgtcagc tgtccgcccg 9061 ctaccaagtc agcaaaagca cagtgatccg cgcgctgcag gagctggaaa agcgccacct 9121 tatctattct gttccgaaaa gcggctatta tattgtgaaa aagtcaggga aatcaaaaag 9181 cgggcagcct ggccccatcg actttgccac atctgcgccg gatcccgatg tgtttccgta 9241 tcttgatttt cagcactgca tcaacaaagc gattgataca tacaaaaacg atttgtttat 9301 ttatgggacg ccaaaggggc ttccatcact catccgcgta ctccgaaagc tcttggccac 9361 tcaacaggta tttgcggatg aacggcatat tttcattaca tcaggtgtcc agcaggcgtt 9421 atccttgctt tgtgccatgc cgttcccaaa tgggaaagag aagatcgcca ttgaacagcc 9481 gggctaccat ttgatggtcg aacagcttga gacacttggg attcccgcca tcggggtgaa 9541 acgaacggaa gaagggcttg atatagccaa ggttgagcgg ttatttcaaa cagaatcgat 9601 taaatttttt tatacgatgc cgcgcttcca taacccgctt gggtgctcat tgtcagagcg 9661 tgataaacag gagcttgtga gactggcaga agcgtatgat gtctatctcg ttgaggatga 9721 ttacctcggt gatctggagg aaaataaaaa ggcagatccg ctgtacgcat atgatctgtc 9781 ctcacatgtc atctatttga aaagcttctc gaaaatgatg ttccccggcc tccgcgtggg 9841 ggcggctgtt ttgcccgaag cgctgactga cacgttctat gcgtacaaaa agctgaacga 9901 catcgactgt tcgatgattt ctcaagcggc attggagatt tacctgaaaa gcggtatgta 9961 cggcaggcat aaggagaaaa tcagagattc ttataaagag cggtcgctga ggctacatca 10021 agccattcga actcacaggc agctgggaag cggacgcttt acgttctcca gcgggcaggc 10081 accctgtatg cacacccatc tggtgcttcc tcaggatctg cccgcctcaa gagtgattca 10141 tagactggaa aaacaagggg ttctccttga ggcgatagac cgtcattatt tatcagatta 10201 tccgaaagaa aatctattaa aaatcaatat ttccaatgtg aaaacggaag atattgagcg 10261 cggtgtcaag ctgttgatga gccatttata aaagctcttc gtacgagacc attgtgatat 10321 cctcggggaa atcagggtgt acggcgcata cagccatttt gtagccggga tcgacctcat 10381 acgttttgat atagcatggg gaatggctgt ccggaagctc aatggatact tgtccgtcct 10441 ggtgcaggcg cactgaaaag gaatcaagcg gaagcgataa gcctttgcct tccttgtttg 10501 ataaagcttt ctttcattga ccatagatga taaaaatagt ctgtctgctc gtccttgtct 10561 tttgctaaaa ggtcgctgta ctctgttttt gaaaagaagc gcttggcgat ctcaaggctg 10621 atcggtttcg ttttttcgat atctatgccg atcggctgtg aatcaaacgc gcaaatgacc 10681 cagcgtccgg agtgagaaat gttgaaatga gcgtcgggaa gatcagggat gcacggcttc 10741 ccgtattcct gcgtgctaaa gcggatatcg gatttgtcca actgatactg cctgcttatg 10801 actgagcgaa cgagcacatc tcccagcagg gtgcggtgag catcttcttt atgataaaat 10861 ctccggcatt tctcccgttt ttcaggtgat atgaaagaca tgaaccgttc attttcttcc 10921 tgtgaaagcg ggcggtccat ataaattccg taaatcttca ttctagatcc tccgtctgca 10981 aaagattgtc aaaaccatcc tatcatactt ccacaagact catatagagg agaaaataaa 11041 aaaacaaagc caaggcggct ttgttttagt gtacaggcgg agatgctttc actgcggctg 11101 tccgccttgc cacagcataa ttcagcaact ggattgactg gggcaatgaa aaacgcaaaa 11161 taagtccggt gaggatggcg gtcaaaatgg tgccaaaacc gatcggtccg cccatgcccc 11221 atgccgcaaa caaaatggtt aattccatgc cgttccgcac ccattgcaca ttccagccgg 11281 ttttttctgt aatcagcatc atcagtgaat cacgcggccc cgcgccaagg cctgctgata 11341 cataaacacc gacgccgtaa ccaatcagca ccacgcctag agagaagacg atgatcgagc 11401 ctgtgtaggt cgagagggca ggcagaatga aattgaaaaa atctataaat acaccaatga 11461 gcaccatatt caggagggca ccaattttcg gccaagctct cgtaaacaat gacgtgaatc 11521 cgacgatgag cgctccaata atgatggacc actggccgac ggtaagcccg aagtgctgaa 11581 acaggctgta atgaaatgca tcccacggac taatgccgag tgcttttcct tctatcgtca 11641 gggatacacc aaaagccaaa atgatcaaac cggcaaaata aaatgtccag cgcagaacaa 11701 gttcttgctt cacgtgaggt cccttctttc gtaaaaatca gtcgattgtc attgtagcac 11761 atctgacaga agggcggaat aggcgaaagg ggctcaacaa aaaaacaggg ccgccggagg 11821 cgccctgttt cagcgtgttg gcaaaccctt gcattcgttg tcaggcctgt gcttcggtgc 11881 tcacgaattt aacattagct gtgctccaat gctcgccctt cctagacttc aaaggttttc 11941 aatcacgctg aaaatcacaa aatcctaaaa cgaatatcgt tttaggattt tgtcaataat 12001 ctgaaacagg gcgctgacgc tctgtttttc ttattacagc gggttcaaaa tccggtttaa 12061 gaaccgctgt gtccgttctt cttttggtgc ggagaaaatt tgctccggcg gtccctgctc 12121 cacgataacg ccgccgtcga tgaagatgac ttcatccgca acctcctgcg cgaacttgat 12181 ttcgtgggtc acgacgacca tggtccagcc ttcattggcc aagtccttga taaccttcag 12241 cacctctccg acaagctcgg gatcaagcgc tgaggtcggt tcgtcaaaca gcatgagctc 12301 aggctgtatc gccagtgcgc gggcgatgcc gacgcgctgc tgctggccgc cggaaagctg 12361 gaacggatat aaatccattt tgtccttcaa tccgacttta tcaagaagct gaatcgcttc 12421 ttttctgact tcctctttgt tccgtttttg cacctgaaca gggccctcca tcacgttttc 12481 gagggctgtg cggtgcggga acaggtgata cgcctgaaac accattccgg attttcggcg 12541 aagctttagg atatccgcct gtttcacctt tttggagaaa tcgatggaga aatcatcaaa 12601 tgcaagctct ccgcgattcg ggatctccag agcgttcagg cagcggagca gcgtcgtttt 12661 ccctgaacct gaaggcccaa gtatggcgat gacttttcct ttttcaatct tcatatctat 12721 cttttttaaa atttcatttt caccgaatga tttgtttaat cctttaacgg taagcatact 12781 cggaacctcc ttatttggcc acgtagcggt caagacgccg ttcgatgaca tgctggacga 12841 gtgagagcag gaagcagata atccaataaa taaaggctgc ttcaatatag atcactaaaa 12901 tttgatcaag attccgcgcg ccgatttcct gggcttttct gaacagctca gcgaccagaa 12961 tttgagaggc gagggatgta tctttaatca ggctgataaa ggtattggat aatggcggga 13021 tcgacacacg aaacgcctgc ggcaaaatga cgcggaacag cgttttttga tgtgtcatgc 13081 caattgtgta gccggcttcc cattgccctt tcggcacgga taaaatagat gcccgaatga 13141 tttcagatgc ataggcgccg acgtttaatg aaaaggcgat aactgcgctt ggaaatggat 13201 ctaatgtgac gttaaaggcc gggaacagat agaaaatgat gaacaattga acgagaagag 13261 gagtgccgcg tattgcggat acgtatacgc tgaacaccca tctcaaaggt ctcactttcg 13321 acattctggc aagcgccgta atcagcgcca ggatcattcc gaatataaag gaaagaatcg 13381 taaggggaat cgtatagtag attccccctg aaagtatcgg ccagaatgac tgctgcacca 13441 gatcccacgg gatcgccgtg ccaagcgtca atgccggcag attatttaga aacatcttcg 13501 ccgaaccatt ttttagaaat tttagaaaga gtcccgtcct ctttcatttc ttttaatgct 13561 ttgttgactt gatcaacaac ctcgccgctt cctttacgga acgtgaaata tgttgactga 13621 ggctcacctg tttcaaacgc gattttcacg tttttattgc cagatgtttt taagtagttc 13681 aatacggcaa gcttatcgtt gtatgtcata tcgacgcggc cttgctggat catttgaagg 13741 gcctgcgcca tgccttcaac gccttctact ttagcgccgg catttgtagc taatttgttg 13801 tagttgcttg tcagtgattg agctgacgtt tttcctttta catctgcttc agacttaata 13861 tcgttgttgt cttttttcgt tacgacaacg gctcttgatg ttgtgtattt atctgagaaa 13921 tcatatttgt cttcacgatc tgtttttccg acttggttgg caacaacgtc aaaccgtttg 13981 gaattcaggc cggcaaacat actgtcccat tgtgtttcct taaagtcgac tttaagcccg 14041 aggcgttttg cgacttctgt gataacttcg acatcatagc cagtcagttt atcagtgtct 14101 ttgtcgtggt aagtgaacgg ctcatatgtt ccttccgttc cgactgtgag cacacctttt 14161 ttcttaattg aagcccaaag atcgccatct ttggcattat cttttgactg attgtcattt 14221 cctgctccgc aagctgcaag agctgcaata cttacgacca tgaataaagc caataatgct 14281 tttttcatct tattccccac ttttctggtt gattttattg aaataaaaaa ttagcttaca 14341 aatctaaagg ataacttttt tttagtatga gtcaagtatt tggttttcat aagacaaaat 14401 cttttaaaat aaatccaaaa attgctgtgc cggtttaggc aaataactgt ccgttctcca 14461 catgacagcc ggtgtcataa tgaagggatt attttcgata tggacggtgt gaacgtgatt 14521 tctcatatga acgggaatca ttgtgacagg caaaatagac gcgccgaatc cggatgacac 14581 gaggctgagc aaagttgcag agtcgtggca ttcacaaaca atgcgcggct ccaggttcaa 14641 acgatgaaat tcattcatga cctgattata gacgcctttt ccgttgacag gccgcagcag 14701 gatcagcgga aatgaaggaa tgtccaccat cttaatggtg tctccgcacg gatatccggc 14761 ttcatctgaa agcacgagca cacatggaat gtcatcaagc tgcttgaatt gtactgtgtc 14821 acttttgatc agtgttgtcg tgaccgccgc atcgatttgc cggctttcca gcagttccaa 14881 cagtgtcgcg ggttcatttt cccaaatatt aaaggtgaga tgggggtatc tctctttgat 14941 ctgtgttact ttttcaagca tcagagccgc gcaataaatc gttgatccca cggcaagtgt 15001 accggctact tcctccttca gctcctgtac ctcaatgact gcatcttcaa acctatgcag 15061 aatctctttt gctcttttta gaaaaacagc tccttcatat gtaagagtca tttgtttttt 15121 cttgttacgg tcaaacagaa caacaccaag ttcgtcctcc agctgtttga gctgcctgct 15181 taaaggcggc tgcgccatgt gaagcttttt ggctgcggac gtaattttct gttcttgggc 15241 aatggtaatg aagtatcgaa gctggcgaat atccaaaaga aagcgcctcc ttatcatacc 15301 ttttaggtat taattataga tttaatagat atttttcata tggatatatc aggagtatga 15361 ttgaaatgaa agcagaattc aagcgtaaag gagggggcaa agtgaaactc gttgtcggaa 15421 tgacaggggc aacaggggcc attttcgggg tcaggctgct gcagtggctg aaggccgccg 15481 gagtggaaac ccatctcgtt gtgtctcctt gggcaaacgt cacgatcaaa cacgaaacag 15541 gctatacgtt acaagaagta gaacaactgg ccacatacac ttactcacat aaggatcagg 15601 cggcagccat ttcaagcggg tcgtttgata ccgatggaat gattgttgcg ccgtgcagca 15661 tgaaatctct cgcaagcatt cgcacaggaa tggcggataa tctgctgaca cgtgcggcgg 15721 atgtcatgct caaggagaga aaaaaactcg tcctcttaac gagagagacg cctttgaacc 15781 aaattcatct cgaaaatatg ctagcgctta cgaaaatggg caccatcatt cttcctccga 15841 tgccggcatt ttataatcgg ccgagaagct tagaggaaat ggttgaccat attgttttta 15901 gaacgttgga ccaattcggc attcggcttc ctgaagcgaa gcgctggaat gggattgaaa 15961 aacaaaaagg aggagcttga tcatggctta tcaagatttc agagaatttc tcgctgccct 16021 tgaaaaagaa ggacagctgc ttacagtgaa tgaagaggta aagccggaac cggatttagg 16081 ggcctccgca cgggcagcca gcaatcttgg cgataaaagc cctgcgctct tatttaacaa 16141 catttacggc tatcataacg cgcgaattgc gatgaatgtc atcggctctt ggccaaacca 16201 tgccatgatg ctgggcatgc cgaaagacac accggtaaaa gaacagtttt ttgaattcgc 16261 aaagcgttat gaccagtttc cgatgccggt caaacgtgag gaaacagcgc catttcatga 16321 aaatgaaatc acagaagata tcaatttgtt cgatatactg cctcttttca gaattaacca 16381 gggtgatgga ggctactatt tagacaaagc atgtgtcatt tcccgtgatc ttgaggaccc 16441 tgacaacttc ggcaaacaaa atgtcggcat ttacagaatg caagtcaaag gaaaagaccg 16501 ccttggcatt cagcctgtcc cgcagcacga tattgcaatc catctgcgcc aagctgaaga 16561 acgcggcatc aaccttccgg tcactattgc gctcggctgt gagccggtca ttacaacggc 16621 ggcatcgact ccgcttctct atgatcaatc agaatacgaa atggcaggtg cgattcaagg 16681 cgaaccatat cgcatcgtca aatcaaagct gtctgatctt gatgttccgt ggggcgctga 16741 agtggtgctt gaaggtgaga ttattgccgg agagcgcgaa tatgaagggc cgttcggtga 16801 attcacaggc cattattccg gcggacgcag catgccgatt atcaaaatta aacgcgtcta 16861 tcacagaaac aatccgatct ttgaacattt atacttaggc atgccttgga cagaatgcga 16921 ttacatgatc ggcattaaca catgcgtgcc gctttatcag cagttaaaag aagcgtatcc 16981 gaacgaaatt gtggcagtga acgccatgta cacacacggt ttaatcgcga ttgtttccac 17041 aaaaacccgc tatggcggat ttgcgaaagc ggtcggcatg cgcgcactca caacgccgca 17101 cggactcggc tactgcaaaa tggtcatagt cgttgatgag gatgtcgatc cattcaacct 17161 tccgcaggtc atgtgggcgc tttcgaccaa aatgcatccg aaacatgatg cggtcatcat 17221 tccggactta tctgtcctgc cgcttgatcc gggatccaat ccatcaggaa tcactcacaa 17281 aatgattctc gacgccacta caccggttgc gccggaaaca agaggccatt attcacagcc 17341 gcttgattct ccgctaacaa cgaaagaatg ggaacaaaaa ctaatggact taatgaataa 17401 ataaggaaag gatgttcgaa atgcatacat gtcctcgatg cgactcaaaa aagggagaag 17461 tcatgagcaa atcgcctgta gaaggcgcat gggaagttta tcagtgccaa acatgctttt 17521 ttacatggag atcctgtgaa ccggaaagca ttacaaatcc cgaaaaatac aatccagcgt 17581 ttaaaattga tccaaaggaa acagaaacag caattgaagt tccggcggtg ccggaacgaa 17641 aggcttgatc cgcgtgaact gtatgtcaga ccgtctcttt gagctgcttg acgggagctg 17701 cctgaatgag aagcagcatg aggccttcgt tctgcaaaca gtatcagagg atggctggcc 17761 gcatgccgct atgatcagtg caggtgaaat catcgcgctg agccgaactg atatccgaat 17821 cgctctgtgg aaaaacacaa tgacttcggc caacatcctt cgcacaggaa aagcacagtt 17881 cacggcgtgg tggaagggag cggcctatta tgtaaagctt gaatgcgcgc ctttaccgcc 17941 tttgaaagat gccgaatatg aaagagaccg tttttcctgc cgcatcgttt cagtgaaaga 18001 ggacgttgcg aaatacgctg atttgacttc aggtgtccgt atacagcttc acagccctga 18061 agaggtgctg agcagatgga aaaagaccct ggaagattta aaacggtaat atcgatagcc 18121 tgacgccatg cgtcaggctt tttttatata atgaaaacaa aagggggcgt gagaaatgga 18181 acgtgcgggg atctgtcact cggacggctt tgatttagct tatcgaattg agggcgaggg 18241 cgcacccatc cttgtgatcg ggagtgcggt ttactatccg cgcctttttt cctcagatat 18301 caaacagaaa tatcaatggg tctttgtcga ccatagggga tttgctaagc ctaagcggga 18361 gcttcgtgcg gaggattcga ggcttgatgc tgtcttggct gatatcgaaa ggatgagaac 18421 atttcttcag cttgaggatg ttactatcct gggacattcc gggcacgctt ttatggcttt 18481 ggagtatgcc aggacatatc ccaaacaagt tcggaaggtg gcgctcttta atactgcgcc 18541 tgataacagt gaagaaagac agcgaaaaag cgaatcattt ttcatggaaa cagccagtct 18601 tgagagaaag aaacgctttg aaaaagacat cgagaatttg ccgcaggaca tcgacaaaga 18661 tcctgaaagg cgctttgtgc acatgtgtat tcgcgctgaa gcgaaaagct tttatcaaga 18721 gcggccgcat gctgctgcct tatgggacgg tgtattcacg aatatgccga tcattgatga 18781 attatggggc aatacatttg cccggattga tcttcttcag cggttagctg atgttcgtat 18841 gccggtgtat atcggattag ggagatatga ttatttggtt gcgcccgttt cgctatggga 18901 tgctgttgac ggtttatatc cccatgttga taaggttatt tttgaaaaga gcggccatca 18961 gccgatgctg gaagaaccgg aagcctttga tcaaagcttc aggaaatggc ttgatcaata 19021 aaaaacagcc cgcagatcaa catccgcggg ctgtttctga ttataagacc cctttcatcg 19081 cgcgtttgat caccggcgag agcagcagga gaatgccgcc aagaacgata gaaatcaaac 19141 cgatggtgcc gaagtacatt gtttcaggaa ttttatcaaa caatccggct acttgggcat 19201 tgatcgcttg ggctgctgcg ttcgtcagaa accacatact cattgtctgt gcagagaagg 19261 cagctggtgc cagtttcgtt gtcacggata aaccgactgg agacaggcac agctctccaa 19321 gcacgacaag caggaagctg agaacgagcc aaagcgggct tacgagtgct tcttttcctt 19381 gcatagcagg gaataccata atgataaatg acaatccggc taaaataatt ccgattgaga 19441 atttaactgg tgtagacggc tgacgtttgc caagcttcat ccagagccat gcgaatattg 19501 gcgcaaaaat gacaacaaac aatggattta atgattggaa ccatgatgac tgaagttcga 19561 atccgcccaa tgaaagtctt atgcgttcat cagcgtatac cgcaagaatg gtcgctccct 19621 gttcctgaat ggcccagaac atgacagcac cgataaacaa aggaacgtaa gcggcaagac 19681 gggatttttc tgttttgtcc gcttttttgc ttgtaaacat gatgatgaaa taaatcacag 19741 gaatcaaaat accgagaata cttacaaggt caatgaaacg tttgatcgtc agcacgcctg 19801 tttgtacaga gataatcact gcgatcgcca caatgataac accgattccg gtgccaattg 19861 cagatttttt agacagcgga ttcggcacat tggaacctgc aagcccgagg tttttctttc 19921 ttgtcaaagc aaatacgata agtccgagaa gcattccgac cgcggcagct ccgaatccga 19981 gatgatagtt gtacttctgt ccgagtgttc cgacaattaa cggcgcgagt aaaccaccga 20041 ggttaatccc catgtagaaa atactgaaac ctgagtcgcg gcgcgggtct tctttcgtgt 20101 aaagatcccc aactacgctt gaaacgtttg gttttaataa gcctgttccg acaatgataa 20161 gcaccatact gatatagaat gctatcgaac tgcccggata ggcgagtgca atgtggccga 20221 acataatgaa tatgccgccg taaaacacgg tgtttgcggt accgaatacc cggtcagcga 20281 gccatccgcc aataatggtg gacatgtata cgagtgatcc gtaaatcgac ataatggcaa 20341 ccgcagtgcc cttgtcaaag ccgagccctc cgtttaccgt ctctgtatac aaatagtaaa 20401 gtaagattgc tctcattcca tagtaagaga aacgctccca aaattcggtg aaaaatagtg 20461 taaatagtcc tcgcgggtga ccaaagaacc ctttttgcgg gacgctttta atgatacttt 20521 cgttatcaat cgaagccatg tcagccaaac cctttctaaa aaaagtgtat tataaaaatc 20581 atattcttat ataatacttg tgtcaatata atttatactc atttcaaata gttccatatt 20641 ggaaaaatta taaataccta aaaatagtga tttcctccta atttttaaac tttttatcgt 20701 gagattttct tacacaacta ttcctttata tttttttaat aaaattttag agaaatgtac 20761 aagcagatcg ggcctttgtg agtaacatga tagtaatcat agagaaggag gctcgcaatt 20821 ggctgaattc atattaaatg cagcggattt cggtgttcct agagatggta aaacggattc 20881 gacagaacgg attaatcagt gcctcagtac agctgtttcg aaaggctatc atactgtctg 20941 gtttccaaag ggaacatatt taatagacgc aacgcttggc ggagatctta atcagaggtt 21001 tcgaaacgcg gggatcattg ttcccggcaa ccttgagatt atgatggacc ccgaatgtat 21061 catgaaagtg ataccgaata gttcgtgggg ttattccgca ttttatgtag gcaagcaaga 21121 gaatataact atttccggag gacaaattat cggcgaacgg gatgagcata cgtatgcctc 21181 ggcggggata aggtcaaccc atgaatgggg ctttggcata tgtattgaag gatgctcgaa 21241 tgttgtcatt gatgatgtga aaatttccga ttttaccggc gatgggatca tagtcagccc 21301 aaggggatta aagaccaatc aagattatcg aacgtcagag caaattatca tccgccgctg 21361 tgaggttcgg cggtcgagga gaaataacat ttccattacc ggatgtgaca tggtcacggt 21421 ggaggaatgc ttgattgaag atgccggaac ggggaatgga acagcgccga aattcggaat 21481 tgacattgaa ggatatggcg aaggtgacgt tgattatgag gaaccgatta atgtatcaat 21541 tcgcaataac cactttgttg gaaacgtttc aagttctgtg accaatttta acgggtatgg 21601 cattttaata gaaggaaatc actcagacaa tacaatcagc tacggatatg ggacgcaaac 21661 agtgatcaag ggcaatattc tgagacgccc tgaagacgcg gcggctgcgc caagagtcgg 21721 gataaccgga ctcggtgtat cacaaggaaa agagaccagt gatgcagtga tcgctggcaa 21781 cctcattacc ggattttcaa ctggaattga tgtcagggga aagagcgttc ttgtgacgaa 21841 caacaaaatc agcaactttg aaaacacagg gatattggtt tatcagtcct ccgacgtaaa 21901 ggtagacgga aaccaaattc aaaacggact gtctgaaaca aggcgcagca tcggtcttcg 21961 cgcagtgctg tcagatgaca tcgcatttct gaataactgt ctcattcaag tcgttgacgg 22021 tgtgaacgtt tccggcggaa atatgatcat taaagataat ctcctgagaa aattcagccg 22081 gggcatttgg attgctcaag ggaacgcggt gattgaaggg aatacactga atcctgacgc 22141 gtttgaagca gtgccggaat catattctgt ttccgtcaca aacaatgccg gcgccatcat 22201 caaaaacaat acatttaaag agttcaaaaa ttaccccatt tattgctcca caagtgcaaa 22261 aacctcaatt atcggcaacc acttagagcg atccccgctt ttggtcacca tctatatcag 22321 cgcaggtgtg catgagattt ttgataatac catttcagtc aacagaacag ccgggaatcc 22381 gattgtgatt tatctcaatg gctctgcagg ctctatcatc tctggaaaca ccatcaataa 22441 cctctccgcg ggcactgcga cagctattca aacaaacacg tcaaccaatt ccaaaatcat 22501 cggcaaccgc atttttaaag ggaccatcaa caaacacagc agtgatacaa tagacggcaa 22561 tatgattgtc tgaaaaaagc gccccccttt aggggttctt ttttttcgat ttatagatca 22621 cgtacatttc tctcacaagt actaacacaa aaaataaaag cacgacccat tccgcaaatg 22681 ttgtcatctt aaagctggac atattgttat aaacggcttt tgttaaactg aacccttgaa 22741 gcatgtccat caacacagaa atagctaata aacaaattaa tatgaatccg gtcacgccca 22801 atatcttcat gcttcatcat cctccgcttt tagtgtctat ctttggcgga gaagttatac 22861 cgcatctaac cctaatgcat aatctcaatt ttaaaaggaa gaatatgaga aaacgacaag 22921 gaaaggtatt tgtgtatgcc tttattttct aagcgaaaga acaataccga ttcaaaagac 22981 aagcagaata cagacgaaag gaatcaggaa cagcagcaag aaaaagaaag gccggttctc 23041 atttctccaa gtttagcaaa gaatatagcg gaaacgaaaa aggaagtcgg aagcagctct 23101 gacgtcatca ttcgcgagat taaaatcggg gagcaggatc atgtccacct agctgttatc 23161 tatatttctg ggctggtcga taataacacg atccatgagt cgttaattga cccattggta 23221 caggatgagt ctatccagaa tactcatgcg atccagcaaa ttcttgaaaa aacgctcccg 23281 ctgggcgggg tgaaagcgga aaagagctgg gacaagcttt tttccgagtt aatgcttggc 23341 aatgcgctca tttttgctga tggccatgat gaagctttga tttgcagcac tcaaggggga 23401 gagcagcgct ccatccaaga gccgagcacc caggtgtcat tccgcggccc gcgccaaggg 23461 tttacagagt ctctgcaaac caatatttcc atgatccggc gatacattaa aaatccgaat 23521 ttatgggttg aaaaaatgaa aaaaggttct gttacgaata cggatatcgc tctcatgtac 23581 attcaaggaa tatgtgatga aaaggtgctg aaggaagtga aacagcgcct ggaaaaaata 23641 gatattgaca gtattttgga atctggatat attgagcagc tgattgaaga tgaaaccttt 23701 acgacgtttc cgactatgta tcatacagaa cgccctgatg ttgtagcggg taatctgtta 23761 gaaggaagat tcgcgattat tgtggacgga acaccgtttg tgcttattgc cccagcctta 23821 tttgtccagt tttttcagtc tgttgaggat tattattcgc gttttgacat tgcgacaagc 23881 ataagaattc ttcgtgtttt agtctttttc atttcgcttg tggcaccagc tgtatacgtg 23941 gcagccacga cgtttcatca agaaatgata ccgactcagc tgttagtggt cattgcggcc 24001 cagcgggaaa ttgtcccgtt tccggctgtt gtggaggcgc tgacgatgga ggttgctttt 24061 gagattctga gggaagcggg agtcaggctg ccccgggttg tcggctcggc agtgtcaatc 24121 gtaggcgcgc tcgtaatcgg ccaggctgcc gtacaggctg gtatcgtctc tccggcaatg 24181 gtgattatcg tggcactcac cgcgattgcg agcttcgcaa caccggcgtt tgcaatggcg 24241 atttcagccc ggcttattcg gtttatcttt attattgcct cagctgttat gggtttttac 24301 gggctgattt tagggatcat tatgatgttt gtccacttat gcagtcttcg ttcattcggc 24361 gttccatata tgtcgccgct tgcacctttt tcttcacaag gcgtaaagga cgcgcttttc 24421 cgggttccgt ggtgggccga tgaaaaaagg ccggaatcgg tcagcaagga agataaggtg 24481 cggcagggga aagatcaacg cccagagccg gccgcttcac gaggaatggt gaacaaagat 24541 ttggaagaag gggatcagaa tggtacgtaa atgtctatta gccgttctca tgcttttgag 24601 cgtcattgtg ctgcccggct gctgggataa gcgggagctg acggatcttg cgattatctc 24661 ggcgattggc atcgatcgga caaacgacag caactacgtg ctgcatcttc aaattatcaa 24721 tccaggaaat gttgccggcg gccttcaggg aggcggtgct ggagacaggc cgcctgtatc 24781 tgtctattcg attgaaggta acaatataac ggaagcactc agaaaagcct ccatgaaggt 24841 atcacggcgg ctttattttg cccataccaa tctagtcgtg atcaatgaaa agctggcaaa 24901 agaagaaggt ttggattttg tattagataa tcttgaccgg gacacagaat tcaggacaac 24961 agcaacattc gtcgttgccc ataaaacaaa agcagaaaat attgtgaaaa tcttgacgcc 25021 gattgataaa attccgtcaa ataaagtcaa taaaacactc gatttcacgg aggcacaata 25081 cgggcgggtg gtcaaaatca atattcagga cgttttgaaa acacttgccg ccaacactat 25141 ggcaccggtc atccccggat atatgatgat tggtgacgat aaaaa //