LOCUS       c00022_gnlPro..        15583 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DADJJIOI_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:21:40
            Original ID  :: gnl|Prokka|DADJJIOI_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15583
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15583
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2143:5583]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2144..5583
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15583
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15583
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(931..1884)
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPAPGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             2144..2818
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_2"
                     /sec_met_domain="SucD_FumR (E-value: 2.1e-66, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             2857..4800
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 5.1e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.3e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             4828..5583
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="Fer2_3 (E-value: 2.1e-25, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.2e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.5e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             5594..5779
                     /locus_tag="ctg22_5"
                     /transl_table=11
                     /translation="MYVYGKARRQWQRAFFMFVQTHKKAALPIIKVDAAFLLLSSETVS
                     RFPLCKDFVNLRSKIL"
     CDS             5776..5934
                     /locus_tag="ctg22_6"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5907..6938)
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLDILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             7044..7454
                     /locus_tag="ctg22_8"
                     /transl_table=11
                     /translation="VLLNNIVVFVHSSNKKRIMVRLTSKEEEILGYFWAKGPLFVRELL
                     DLQEESKPHYNTLSTIVRSLEEKGYIGYKVYGNTHQYYALVSEDEYRRNSLKQVISKYY
                     DNSYTRVVSTLIEEEVLTIDELQKLIQQIKNK"
     CDS             7468..8100
                     /locus_tag="ctg22_9"
                     /transl_table=11
                     /translation="MDAFLLYILKSGICLTVFYVCFKALFSNDTFFRFNRWILLVGTGV
                     CMLLPLCRIQTARPFPLSRPVSQLEIVFYEEEMKAFPVPESKEEITIPTEQRNISVPWT
                     GIIGIAFLTGSGICLTTTILSFGKMYQLTRKNRKLKQGKYTLILTPDPVSPFSWGRYIF
                     LSENDYRNHPNEILMHEKMHLRYNHSVDLIYMKRFFFCNGLILPYGY"
     CDS             8268..9236
                     /locus_tag="ctg22_10"
                     /transl_table=11
                     /translation="MMLKKKSNNWARLKLALLVPVGFAALSAFARPETSPPPAATMTDN
                     IHLSINKSTVNQETMQQDHAVFLTYKESGSEDLNSIVCKTLDRIRTRVAEGQFKNALEV
                     TVNPAFDDIPASYLETVKDVLEERDIKCKIDMTVPNTIMDDVAKPYRKYDDVVYLIQNK
                     KIVAALSISKFSANQNDPRLDKISKSASLILQPENPKVSRQEMEKLKNLLDKKGLTSEI
                     NMNIFKIGDAAAPPPPPPAGQVIFSYRDGQPDQQFVLYDRHAKPGANLGQRIDKIYKDN
                     ITKVSIKINKSTPKDLLETVKQELKKKINYPVQYEILQFVD"
     CDS             9348..10583
                     /locus_tag="ctg22_11"
                     /transl_table=11
                     /translation="MIHNVKILFFICFFTACSSTEQKEIVTAGELLRQAAFYGERLQFL
                     PALETYQQAIKLAEKEKDSTVFSLAYLEMGKIYRYQSLKQKALQSEKKALSYIKSPACD
                     SLRLELYREIGDMYTLSGQADSAFHYYEMAGCRIKQAKILQQNGSNKEAETLLKTELEQ
                     TIFPKEKAEVCLALADLQITLGKLDEAEKSLSQVPPSHPHLYAALSRIAQSRGDSLQAD
                     FYHKSYLHHLSVLRQEKEQNQITQLLRTSEQKEWEKRLTDSQKAQKEQIYVWVTLLVSC
                     STGIWGYSRYRQKRNVVSLSETDFFSSEIYLRFHRKEEWKPVPKDWEELLQAFNRTYPD
                     FRERLKRKIPKLSEQEWRMCCLIKMEVPPSTAAMLLCCTNQAISMRRVRLYQKITGEKG
                     TPELCDSFIRDF"
     CDS             10650..11846
                     /locus_tag="ctg22_12"
                     /transl_table=11
                     /translation="MKKMLFGLMTAIATFTGCESKQPAGELPRIDLTATSFAFDQVEIA
                     DEIESIEYVPLELTDESLIADVLDLCVSDEYIFVYSTRQDGVLQFDRKGKYLRCIAKTG
                     NGPGETGQIISLTVDEENRLFCVSEYFSTSFYSFDGEFIKKIENPRPYSYQFSVGPNTM
                     AELGRMYVPMNTPGMFSLGVFNWGTDDTIAFRHTIGDMDLMPLEETSLKGWIFSGSKDG
                     ILCYSEGIDTVWDVNARNIAPAFLINTGYSVEEEKEMRSSKTGNEAVDGKYSVFSFFET
                     PRHYFVKCFEGSNQSKFYLYGLDKATGELKRETSPLNAQELFKNNWTLAGIGFRNTKDN
                     GLPIWPYLSYPGKKQMVQFNTAVEIEYLKEKYPDLKKHLVLQQITEDSNPLITIYHLR"
     CDS             11889..13160
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_13"
                     /sec_met_domain="Peptidase_U32 (E-value: 2.9e-68, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKNLNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSR
                     SSNNFTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAAD
                     VAAMNYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQ
                     QITGPKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDS
                     NIELDIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRA
                     YCNGTFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIK
                     YFDKIGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLK
                     VNEKIRPSDRLYKMEKVQLEKVFE"
     CDS             13160..13567
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_14"
                     /sec_met_domain="HBT (E-value: 1.8e-07, bitscore: 25.6,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 2.6e-08, bitscore: 28.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNAYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             13564..14679
                     /locus_tag="ctg22_15"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRVGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATPVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
ORIGIN
        1 agttctatca gaactatggt ttttaattat ctcatatccg ggtcaaaggt atgaaatttt
       61 catttcgttg tatgtttttt tattaaaaaa gttcatatag cactcatttt taacaattca
      121 gacttacagg ctaccaacaa gcatcagaca atatcagact tttgaacctt tttaagcaca
      181 agaagtaatt tgcggcttat cattcaactc tatttttgta caatattcac acttatcaga
      241 tacatttctt cataaataca tgagttctga tagaacttat atctctttct gtgcatgggt
      301 ggtcaaaaaa taatcttatt tttataatat tgcatatttg tctgaaagtt ttgtggttat
      361 gcatattctc atcagcacag aacatgattt tgtatctgtc gaaaaactgg gaaaagggca
      421 ataggcaatg aaatacaatg cctgtgttaa tttatctaat tttagtgcaa ctttattgaa
      481 gctcagtagt cgggatgggg tgatttctag gatgtttttt catgaacatc tgtcactcta
      541 tcactaaatg tcgtgtgagt cttgataatc agtgcgtatc tgaagtgata gatacctgtt
      601 ttatatatca cgcttctatc actatctgta atcgctcatc tatctgtttt aaatgaataa
      661 actccaagca ttttaaggta aaagtaggga gacaatttta tcaacacccc catgtatccg
      721 cccccgacac ccggatctta cgctcttata gatccgggtg tcgggggcgg atacatgggg
      781 gtgttgggta agttttatta cgtgtttttc attgatttgt agctgtattt acataaaaga
      841 gccttgtctt tgatgatata ggagaacaag ccctttttcc ttttcttgtt taccttgccc
      901 tgcaaattgt cagtttgttt tagtagaaat tcaatcacgt tcgaaatcgg acagcacttc
      961 tgccgtagta gcgttgatgt tcttgtccaa tacataaatg cggtaagaca ggctcagttc
     1021 tttaccgggt tccaatgtga atgccttctg cttggtcggt gagaaattcc acatgacgtc
     1081 accggcaggc ttgttgacag ttttgtccca tacgcgtaag ggctcaggat agtttaggtt
     1141 ggaaggggag gcaacgatta ggatacaggc cttttcgttt ccggctttcc cttggtagta
     1201 gcaccaacgg gctctcgaac cgtcagcttc gtcgcgggaa aggccttccg aggtgagcat
     1261 ttcggctgtc tgatcgttcc agtcttcgcg cgtacggatg catatgccgc cataacggta
     1321 agcttccatg gtgatcgggc tggggctggc gaggcggata gtggtatgat agtcgatgta
     1381 ataacctggt aaggatgttg tcccgatgtt gatctccagg cgttcgttca ttgctacttt
     1441 ttctgcggga gaatcggggt agaccacatg gtccagtgtc gcaacaaaac cgttgtcgga
     1501 tacgtgttcg aagttgcgga agcgaactgt tccttgtttt ttgtggagat tccagaaatc
     1561 gatctcgttt ccttcgaacg tggttttcgt ccaggcatac cacaaaccga aatgatggta
     1621 atggtcggcg ggagaacaat tggtcatcac ttcgcctccc aatgtcttca aaggatggat
     1681 gaaaccgctg cgtttataga ccgagtcaac gccaggggct gggtaaaccg tggtatagtt
     1741 gtaagagaac aacagtttat ctcctatctt atagtctaag gttttccccg tgtcgacgac
     1801 ggaacaggat gtttcggaag gctgacaaga gcctaagaac agagaaatca aaaaaacacc
     1861 aatagaaaaa atagcagttt tcataatatg acaattaaat aataatcagt tatccggcaa
     1921 gaccttgcct gtatcggcta caaaaaaacg aaattttttc gtttcgcaca atccgtttgt
     1981 gatatctgat gcaaataaaa ccagccagca agcagcgttc taattgatga aatatttctt
     2041 taatcgtttg cgtgatatgg ggatttagca tacctttgca cgataataac catagattgg
     2101 aggaaatttc taaatacaat taaataactt aaattattat cttatgtggt tacttaattc
     2161 ttctatcggg aagaagctga taatgagtat atcaggtctt tttctcattc tgttcttggt
     2221 gttccactta tgtatgaaca ttgcggcagt attttctggt gaagcgtata acgtgatttg
     2281 cggtttgctg ggttctaact ggtatgcttt gctcggtaca ttggtgttgg ctgcaggtgt
     2341 agtcgtgcac ttcgtgtatg ctattatctt gactctgcag aatcgtaagg ctcgcggtaa
     2401 cgaccgttat gccatcaacg ctcgtccgaa aggtgttgaa tgggcttctc agaacatgtt
     2461 tgttttgggt gtgatcgtta tcctgttcat ggttctgcac tttactcagt tctggtacaa
     2521 catgatgttt gccgaactgg caggtattca tggtgacatt catccgcagg atggtgcagc
     2581 gtttatcaat ttctacttcc agggcaatgt tgtgaatacg gtgttgtatc tgatctggtt
     2641 cgttgctctg tggtttcacc tgactcacgg tttctggtct gcgattcaca caattggctg
     2701 gaacaatacc gtttggttaa gccgttggga atgtatctct aaatgggttg ccactattat
     2761 ttgtggctta ttcgctgtta tcacagttat cttctacctg aacggtgtag gtgcttaatt
     2821 tcggatatta ttttttcaat ttgaaaataa aacattatga ctcaaataga ttctaaaatt
     2881 cctcaaggcc cgttggctga gaagtggaca aattataaaa atcaccagaa attggtgaat
     2941 cccgcaaaca aacgtcgttt ggacataatt gtagtaggta ctggtctggc gggtgcttct
     3001 gctgctgcct ctctggctga aatgggattc aatgtattga atttctgtat tcaggactct
     3061 ccccgtcgtg cacactctat cgctgcacag ggcggtatca atgcggcaaa gaattatcag
     3121 aatgatggtg actcggttta tcgtctgttc tacgatacaa tcaaaggtgg tgactaccgt
     3181 gcccgcgaag caaacgtcta tcgtttggct gaagtgtcaa actctattat cgaccagtgc
     3241 gtagcacagg gtgtaccatt cgctcgcgaa tatggtggtc tgttggataa ccgctcattc
     3301 gggggtgctc aggtatcccg tacgttctat gctcgtggtc agaccggaca gcagctgctg
     3361 ttgggtgctt actctgcatt gagtcgtcag attggtttgg gaaaggtgaa gatgtacaca
     3421 cgccatgaaa tgctggatgt tgtgaaggtt gacggacgtg ctcgcggtat tattgcccgt
     3481 aatttgatta ccggtaagat cgaacgtttt gccgctcacg cagtcgttgt tgcgacaggt
     3541 ggttatgtaa atacattctt cttgtctact aacgcgatgg cgtctaacgg ttctgctgca
     3601 tggcagtgct acaagaaagg ggcttacttt gctaatcctt gtatggtgca gatccacccg
     3661 acttgtgtgc cggtgaaagg tgacttccag tctaagctga ctttgatgtc agaatcactg
     3721 cgtaacgacg gccgtatctg ggttccgaag aagctggaag atgcgaaggc attgcaggcc
     3781 ggaacaaaaa agggaaagga tattcctgaa gcagatcgcg actactatct ggaacgtcgt
     3841 tatccggcat tcggtaactt ggttcctcgt gacgtggctt cacgtgccgc taaagaacgt
     3901 tgtgatgccg gtttcggtgt aaatagcacg ggcttggctg tattcctgga tttctccgat
     3961 gctatcaacc gtctgggtaa ggaagtggtt aaacagaaat atggtaacct gttcgatatg
     4021 tacgaagaga tcacgaacga tgatccgtac gaaactccga tgatgattta tcctgcattg
     4081 cactactcaa tgggtggttt gtgggtagac tatgaattga tgacttctat tccggggctg
     4141 ttcgcaattg gtgaagccaa cttctctgac cacggcgcta accgtctggg tgcttctgct
     4201 ttgatgcagg gattggccga tggttacttc gtattgcctt acacgatcca gaactatctg
     4261 tctgaccaga tccaggttcc gcgctttagc actgacctgc ctgaatttgt ggaagcagaa
     4321 aaggctatta acgcccgtat cgcgaagttg atgaacgtga agggtaaaga aacagtcgat
     4381 tctatccacc gtaagctggg acatatcatg tgggaacacg tcggtatggc acgcgacgcg
     4441 gaaggcttga aagaagctat ccaaatgttg aaagacctga agaaggaatt ctggagcaat
     4501 gtattcattc cgggtgaggc caatagcttg aacgtggaat tggacaaggc attgcgtttg
     4561 gctgacttta tcgaaatcgg tgcgttgatg gcacacgatg cgttagaccg tgcagaatct
     4621 tgtggtggtc acttccgtac ggaacatcag accgaagaag gcgaagctat gcgtcatgac
     4681 gataagttca tgtacgtctc ttgttgggaa taccagggtg aagacaaaga cccggttatg
     4741 ctgaaggaag atttgaacta tcagttcgtt gttcctcaaa cacgtaacta caagaagtaa
     4801 taatcatcaa tcacaaaaat tagaatcatg gataaagata taaaggtaac acttaaagtt
     4861 tggcgtcaga aaggtccgaa agataaagga cagtttgaga cttaccaaat cgacaaaatc
     4921 aatcagagtg tttctttctt ggaaatgtta gacattttga atgaacgttt ggttagcgaa
     4981 ggcaaagaac ctatcgtatt cgaccacgac tgccgtgaag gtatctgcgg tatgtgttca
     5041 ttgtatgtaa acggacatcc gcacggaccg gcaacaggtg caacaacctg tcagctctat
     5101 atgcgccgtt tcaatgatgg tgagacgatt acgatcgagc cgtggcgttc tgctggtttc
     5161 ccggtaatcc gcgacttgat ggtagaccgt tatgcttatg ataagattat ccaggcaggt
     5221 ggtttcgttt ctgtaaacac aggtggggtt cctgatgcta atgcaattcc tatttctaag
     5281 gctgatgcgg atttggctat ggatgctgct gcttgtatcg gctgcggtgc ttgtgctgct
     5341 gcttgtaaga acggttcagc tatgctgttc gtctctgcaa aggttagcca gctggctctt
     5401 ttgcctcagg gtaaggtgga agctgctcgt cgtgcaaaag caatggttgc taagatggat
     5461 gaactgggct ttggtaactg tacgaacact cgcgcttgcg aaatggaatg tccgaagaac
     5521 atctccgtta gcaacatcgc tcgcttgaac cgcgagttca tctctgctaa gttacaagac
     5581 taatacatta tatatgtatg tatatggaaa agcccgtcgc caatggcaac gggctttctt
     5641 tatgttcgtt caaacccaca aaaaagccgc actccctata ataaaagtgg atgcggcttt
     5701 tttgttgctt tccagtgaaa cagtctctcg attccctctc tgcaaagact ttgttaacct
     5761 tagatctaaa atactatgaa aaaaactcac tgcaaatata aagtatattt actgaatacg
     5821 caagagtttg taattacatt ttattgcaaa tttgctactt tttgttttaa aattgacact
     5881 gtgtgcggat tcacactgtt attatatcaa caatcgatcg attctgacac ttgagagtcg
     5941 ctttgaaatc cgtatcctgt atgaaatttg tcggggatgg aatccagaat gtcgaataat
     6001 gcttccactg tttccgcacg tagcatggcg acgcgtgtct gcttgaagtc tgcaatacct
     6061 ttaaacagcg gagttgcagc caaatggcgg cgaatgtgga gaattccccg gcgctcatcc
     6121 aaacgttcca cgctttgttc cacctgcttt ttcagtatgt ccagatacca tgaaaaagat
     6181 tcggcaggca atgtctcgcc tgtatccaga taatgcctca cttctctgaa aatccagggg
     6241 cggcctatgc tgccccggcc aatcataacg gcatccacgc catattgttc gaaacgttgt
     6301 ttgcagattt cggcggaagt cacatcgcca ttgccgatga tgggaatttg tatacgggga
     6361 ttgtttttta cttcaccgat cagtgtccag tctgcctctc ctgtgtacat ctgtgcccgg
     6421 gtacgtccgt ggatggaaag ggctgcgata ccgcaatcct gtagctgttc ggccaagtct
     6481 acgatgatcc ggttgtcggc atcccagccc aagcgggttt ttacggtgac agggatgttc
     6541 accgctttga cgacttcacg ggtgatgtcc agcatcagtg gaatattgcg cagcatgccg
     6601 gcgcctgctc ctttgcctgc cactcgtttg acagggcaac cgaaattgat atcgagaatg
     6661 tccggatgag cggcttcgca aatttgcgcg gcttcgacca ttgtcggaac atcacggcca
     6721 tatatttgta tggcgaccgg acgttcttca tccgccacat tcagcttttg ctgtgtttta
     6781 tttacactgc ggattagggc gtctgctgaa acgaattcgg tataaaccat atcggcacca
     6841 aaacgtttgc acatcaaccg gaaagaaata tctgtaacgt cttccatcgg agctaagaag
     6901 acggggcgtt cgcctaaatc tattgtacct attttcatat ttatattatc aatgacgggg
     6961 acaaaggtac tgatttcctg ctaaaaacag ggataaaagg atatctacta aaaaatatag
     7021 taaaataact atatgatata gttgtgttac taaataatat agttgtattt gtgcattcct
     7081 ctaacaaaaa acggattatg gttagattaa catcaaaaga agaagaaata ttgggctact
     7141 tttgggcgaa aggccccctg ttcgttcgcg aactactcga cttacaggaa gaatctaagc
     7201 cgcattataa caccttgtcc acgattgtcc gctcattgga agaaaaagga tatatcggat
     7261 acaaggtata cggtaatacg caccaatact atgcactggt atcggaagac gaataccggc
     7321 gtaattcctt gaaacaggtg atcagcaaat attatgacaa ctcgtacacc cgtgtcgttt
     7381 cgacgctgat agaagaagag gtgctcacga tcgacgagtt acagaagctg atccagcaga
     7441 taaaaaacaa ataaaaaacc aacgcttatg gacgcttttc ttctatacat attaaaatct
     7501 ggtatttgcc tgacagtctt ttatgtctgt ttcaaggcat tattcagtaa cgacacgttt
     7561 ttccggttca accgctggat attactggta gggacaggag tttgcatgtt gctgccactt
     7621 tgccggatcc aaacagcccg gccttttcct cttagccggc cagtcagcca actggagata
     7681 gttttctatg aagaagagat gaaagcgttt cctgttccgg aaagcaaaga agaaattacg
     7741 attccgacag agcagagaaa tatatctgtt ccctggacgg gaattatcgg gattgctttt
     7801 ctaacaggca gtggtatctg cctgaccaca acgattctgt cattcggaaa aatgtatcaa
     7861 ctaacaagaa aaaacaggaa actaaaacag gggaaataca cgttaatcct gactcccgat
     7921 cccgtatccc ctttcagttg gggacgttat atattccttt cggaaaacga ttaccggaac
     7981 catccgaacg aaatcctcat gcacgaaaaa atgcacctcc gctataacca ttcggtcgat
     8041 ctgatctata tgaaacgatt cttcttctgc aatggtttaa tcctgccgta tggttattaa
     8101 aaagggaatt acggggcata cacgaatacc aggcggataa aggcgtactc agtcaaggca
     8161 tcgatgcaac aaaatatcaa ctattactcg tgaaaaaagc tgtcggctcc agcctctaca
     8221 ctcttgccaa cagcttcaat cacagtaaaa ttaaaaaacg tattactatg atgttaaaaa
     8281 agaaatcaaa caattgggcc cggttgaagc ttgcgctcct ggtcccggta ggcttcgcgg
     8341 ccttaagtgc attcgcccgt ccggaaacaa gtccgccgcc ggcagcgaca atgaccgaca
     8401 acattcatct atcgattaac aaaagtacgg taaatcagga aacgatgcaa caggatcatg
     8461 cagttttcct cacctacaaa gaatcgggtt cggaggatct gaacagtatt gtatgcaaaa
     8521 ctctggacag aatcagaaca cgagtagcgg agggacaatt caagaacgcc ctggaagtta
     8581 ctgttaatcc ggccttcgac gatatcccgg cttcttatct ggaaacagta aaagatgttt
     8641 tggaagaaag agatattaaa tgcaagatcg acatgactgt tccgaatact atcatggatg
     8701 atgttgccaa accttaccgc aaatatgacg atgtggttta tctgattcag aataaaaaga
     8761 ttgtcgcagc actaagcatc agtaagttta gtgcaaacca gaatgatccg aggctggata
     8821 agatatccaa atcagcttcc ttaattctcc aacctgaaaa tccgaaagta tccagacaag
     8881 aaatggagaa attaaaaaac ttgttggaca aaaaaggatt gacaagcgaa atcaacatga
     8941 atattttcaa gatcggagat gctgcggctc cacctccccc acctcctgcc ggacaggtta
     9001 ttttcagtta ccgggacggg cagccggacc aacagttcgt tttatacgat cgccatgcca
     9061 aaccgggagc caatctcgga caacgcatag acaagattta caaggacaat attacgaaag
     9121 taagtataaa gattaacaaa agtactccca aagacctgtt ggaaacggtt aagcaagaac
     9181 tgaaaaagaa aatcaattac cctgtccaat acgagatcct gcaattcgtc gattaaaatc
     9241 agaaacacgg attatctatt tatcatcctc tccgtttaca aaacctgctc cagggggtaa
     9301 acggagagga atattattat ctttactcct tcaaaagaag gattcagatg atacacaatg
     9361 taaagatact ctttttcatt tgctttttca ccgcctgttc ttctaccgaa caaaaagaga
     9421 ttgtcaccgc cggagagctc cttcgacagg ctgctttcta tggggaaaga ttgcaatttc
     9481 ttccggcatt ggaaacctat caacaggcaa tcaaattggc ggagaaggag aaagacagca
     9541 ccgtcttttc ccttgcctac ctggaaatgg gaaaaatcta tcggtatcaa tctttaaaac
     9601 aaaaggcact acaaagtgag aaaaaagcat taagctatat caaaagtcct gcctgcgatt
     9661 cgctacggct ggaactttac cgggaaatag gggatatgta taccttgtcc ggacaagcag
     9721 acagtgcctt tcactattat gaaatggctg gatgtcggat aaaacaggca aagatattgc
     9781 aacagaatgg aagcaataaa gaggctgaaa ctttattaaa aacggagttg gaacaaacga
     9841 ttttcccgaa agagaaagca gaagtatgtc tggctttggc tgatttgcag attactttgg
     9901 gaaaattgga cgaagccgaa aagagtttaa gtcaggtccc cccttcccac ccgcatctgt
     9961 atgctgccct gtcccgcatc gcccaaagcc gtggagacag cctgcaagct gatttctacc
    10021 acaaaagcta cctccatcac ttatccgtcc tgcgacagga aaaagaacaa aatcaaatta
    10081 cccaactcct tcgtacctcg gaacagaaag aatgggaaaa acgtttaacc gatagccaaa
    10141 aggcacaaaa agaacaaata tatgtctggg tcacgctact tgtctcttgc agtaccggaa
    10201 tctggggata ttcccgctac cggcagaaaa gaaatgtcgt ttccctgtcc gaaacagatt
    10261 tcttttcttc agaaatctac ctgcgcttcc accgaaaaga agaatggaaa ccggttccca
    10321 aagactggga agaattgttg caagctttca accggaccta tccggatttc cgggaacggc
    10381 tgaaaaggaa aataccaaag ttgagcgaac aggaatggcg catgtgctgc ctgatcaaaa
    10441 tggaagttcc cccttctact gccgccatgc tcctttgctg cacgaaccag gcgatttcga
    10501 tgcgccgcgt acgcctgtac cagaaaatca caggtgaaaa gggcactcct gagctgtgtg
    10561 attcctttat tcgtgatttt taagcagatg tgaactgatg tgaaaccggg gaaatagccg
    10621 tatcttctac ttttgtctaa aaaaagcgta tgaaaaagat gttgttcggg cttatgacag
    10681 ccattgccac ttttaccgga tgcgaatcca aacaacccgc cggagaactc ccccggatcg
    10741 atctgacagc aacaagtttt gctttcgatc aagtagagat tgcagacgaa atcgaatcca
    10801 tcgaatatgt tccgttggaa ctaacggatg aatccctgat cgcagacgta ttggatctgt
    10861 gtgtttcaga cgaatatatc ttcgtctatt ctacccgtca ggacggtgtc ttgcagttcg
    10921 accggaaagg gaagtacttg cgctgcatcg ctaaaacagg aaacgggccg ggagaaaccg
    10981 gacagatcat ttcgctaacc gtagacgaag agaaccgcct cttctgtgtc agcgaatact
    11041 tctccacctc tttctactcc tttgatggag aatttatcaa aaagatagag aatccgcgcc
    11101 cttactcgta ccaattctct gttggcccga atacgatggc ggaattaggg aggatgtatg
    11161 ttcccatgaa cacgccgggc atgttcagtc tcggagtctt taattggggc acagacgata
    11221 cgatcgcatt ccggcatacg atcggggata tggatctgat gccgttggaa gaaacgagcc
    11281 tgaaaggttg gatattcagc ggcagtaagg acggcatact atgctattcg gaagggatag
    11341 acacggtctg ggatgtaaat gcaagaaata tcgctccggc ttttcttatc aacacgggat
    11401 attctgtcga ggaagaaaaa gaaatgcgct cttccaaaac cggtaatgag gcggtagacg
    11461 ggaaatatag cgtcttcagc ttctttgaga caccccggca ttacttcgtt aaatgtttcg
    11521 aaggttccaa ccaatccaaa ttctatttgt acggcttgga taaggctacc ggtgagttga
    11581 aacgtgaaac ttctccgctt aatgcccagg aattattcaa aaacaactgg acgctggcag
    11641 gaataggctt ccgaaatacg aaagacaacg gtcttcctat ctggccttac ctgtcttatc
    11701 ccggcaaaaa acaaatggta cagtttaata cagccgtgga aatcgaatat ctcaaagaga
    11761 aatatcctga tctcaagaag catctggtcc tgcaacagat aacggaagat tcaaatccgc
    11821 tcatcacgat ttatcatttg cgctgatctt ctcggatatt attcctacct ttgcgaacga
    11881 accagtaaat gtataagaac ttgaacgaga aagattttga aataatggcg cctgtcggtt
    11941 cgtacgaatc actgatggcg gctatccaag ggggagccga ttctatctat ttcggtatcg
    12001 aaggattgaa tatgcgttcg cgctcttcca ataactttac gacagacgat ttgcgcaaga
    12061 tcgttgcgct ttgtcgtgag cacggtatta agagctattt gaccgtcaat acggttattt
    12121 atggggaaga cctgcctctg atgcgcgaga ttatcgatgc ggcgaaggag gcggaagttt
    12181 cagcgatcat tgcggccgat gtggcagcta tgaactatgc caacagcatc ggacaggagg
    12241 tgcatctttc cacacagctc aacatttcca atgcggaagc actgaaattc tatgcccgtt
    12301 ttgctgatgt tgtcgtcttg gcgcgtgagc tgaatttgaa acaggtgcat gaaatctatc
    12361 ggcagatcgt cgaccagcag attacgggac cgaaaggaga actgatccgt atcgaaatgt
    12421 ttgcccacgg agctctctgt atggccgttt ccggtaaatg ttacctgagc ctgcacgaaa
    12481 tgaacgcttc cgccaaccgg ggagcttgca tgcagatttg tcggcgtgct tattcggtaa
    12541 aagataaaga cagcaatatc gaactggata tcgaaaacca gtatattatg tcgcctaaag
    12601 accttaagac aattcatttc atgaataaga tgatggatgc aggtgtacgg gtattcaaga
    12661 tcgaaggacg tgcccgcggt cccgaatatg tccgcctggt gaccgaatgc tataaggaag
    12721 ctgtgcgtgc ctattgcaat ggcacgttcg atgaaaagaa agttgccgct tgggacgaac
    12781 gcctgcgcag tgtgttcaac cgaggattct gggatggcta ttatttgggg caacggttgg
    12841 gtgagtggag tagcaaatat ggctccggcg cgactaagaa gaaagtgtat gttgccaaag
    12901 gaatcaaata tttcgacaag atcggcgtgg cggagttcga aatggaatcc ggtaacctga
    12961 aagtgggtga tgagatcctg attaccggac cgacaacggg tgcggttatg cagacgatag
    13021 aagaaatccg tgtggacttg aagccggtgg acgagaccgt taaaggtgaa cggttctctc
    13081 tcaaggtgaa cgagaagatt cggccgtctg accgattgta taaaatggaa aaggttcaac
    13141 ttgaaaaggt atttgaataa tgaaagagta tatttttaaa ctgacagaca aggtccgtga
    13201 ctacgaatgc gacctgcaag gagtggtcaa caactccaat tatcagcatt atatggaaca
    13261 tactcggcat gaattcttgg agtcgcttgg cgagaacttc ggaaagatgc acgaaaaagg
    13321 ggttgacgga tttgtatcgc gggtagaaat ccagtataag acctcgctca agagcggcga
    13381 cagctatatc tcttgcctca atgcctataa aaaaggagtc aagctcgtat tcgagcagga
    13441 tatatatagg gcttctgaca atgcattggc gacgaaagga atcgtcgagt cggttatcgt
    13501 tgagaacgga aagttgacac gcggtgaata tttcgacgaa atgctaaaaa gaatagaaca
    13561 tacatgactg acaaacggat ttaccaaatc ggccttacta tgataaacgg cgtgggagat
    13621 atcctggcgc gtcatctcct gcaggctttg ggagaagcag aggctgtgtt tactgaaaag
    13681 caacagttgt taggaaggat ccctggtatc ggcagcaata ttgctgccga aatcaaacgc
    13741 ccggaaatct tgcaacgggc ggaaaaagag ttggctttta tcgagaaaaa caatatttcc
    13801 tgttattatc tgactgatac agattatccg gtgcgcttga gagaatgtcc ggatgcccct
    13861 atacttttct attttaaggg aaatactaac cttgatgcga cccgtatcat cagtattgtg
    13921 ggtactcgca acgcgaccga atatggtcgg gagcttaccg aatcccttat aaaagacttg
    13981 gcaaaagtga tcccggactt gttggtcgtg agtggattgg cttacggcat cgatatctgt
    14041 gctcaccgga acgctttgta caaccgactt ccgactgttg ctgtgctggc gcatggcttg
    14101 gatcgtatct atccttcctg ccatcggaat acggctgtcg aaatgctgga atcgggcggt
    14161 ctgttgaccg attttcccag cggtacagaa ccagaccgtc caaatttcct ccggaggaac
    14221 cggattgtcg ccggaatctc ggattgtacg atcgtggttg aatcggcaga aaaaggaggc
    14281 tctttggtaa ctgccgatat tgcattctct tatggccggg atgtctatag ctttccaggg
    14341 cgtgtcggtg acagccattc caaaggatgc aacaatttga tccgacaaaa taaagccggc
    14401 ctgatcactt ctgcggacga tctgctctcc gctctttgtt gggatatcca agctggggct
    14461 actcccgttc aaacggagtt gtttttcgcc gaagcggaaa cattcacctc ggaacaaaat
    14521 ccggttttag ccattatgcg aacgcggaat gagattcata tcaacgagct tgcctcagtg
    14581 ttggagatac cggtacatca actctctatg ctattgttcg aactggaaat aaacgggaag
    14641 gtaaaagcgt tgccgggaaa tctctataag ctgtcctgac cggctttttc gtatacgatt
    14701 tgtatgtggg agaagaaacg gaacctctat aaacaattaa aggctgtctc acgacaaccc
    14761 ctaaccaact ttgttaacct taaatctaat actattatga aaaaaccaca ttgcaaagat
    14821 actctcgtca agagcgtttg tcaagcattt tgttgctaat acttgttaat cagatgagca
    14881 taaatagcaa aaagatttta atcggctata aagagtcctt taaactgcgt tattttgtta
    14941 aatcgagtcc ttgaaacagg tacggatagt ccgtttcgat cacgtcggga cgagtgctga
    15001 tctctgaccg gtaaccggcg gttttctctg tttccgtttt cgcgcgatca tgtgtcggag
    15061 caacggaaat catgcacatg actccgttac ggtgcagagc gtcatacagt ggttgctgtt
    15121 caggcttcat cttcgggcct acataagcca ttacctgttt ccaggggatg ccggcttttt
    15181 cataattatc gaattcttcc cgattcttac accagcaaga aaacatcgca tccggtttcc
    15241 ggtcgagata atagcgggct tgactggcgt tatgtaccgt gtacatgacg ttaacaggct
    15301 tttctgtttc tataaaatca gccataactt ctaaaggtac atccttgata tccaaattca
    15361 ggattgtttt gcctttgctc cattccaggc attcttttaa agttggaatt ttgaaggctg
    15421 tcacgttgcc gtttcggtcc accagattga attgttgcag ttctgcataa gtgtaatctg
    15481 aaacctttcc tttcccggta gttgtccggt cgatggtttc gtcgtgcatc aatacgatta
    15541 tcccgtcttt tgtcaaacgc ggatctatct cgaaaaacga ttc
//
