LOCUS       gnlProkkaODLGFHOP_30   17923 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ODLGFHOP_30.
ACCESSION   gnlProkkaODLGFHOP_30
VERSION     gnlProkkaODLGFHOP_30
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:52:53
            Original ID  :: gnl|Prokka|ODLGFHOP_30
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 19857
            Orig. end    :: 37780
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17923
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10734]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10734
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..17923
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17923
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(1052..1279)
                     /locus_tag="ctg30_15"
                     /transl_table=11
                     /translation="MSQSKIKLNATEEVQEFVNAASRCDFDIDVYYNRFLIDAKSILGV
                     LSLDLTRELTVDCHGESREFDRTLKKFAVA"
     CDS             complement(1549..2970)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_16"
                     /sec_met_domain="GATase_7 (E-value: 2.4e-23, bitscore:
                     73.4, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGIKEECGVFGIYDLDGGNVVPSIYYGLTSLQHRGQESCGLAVS
                     DTKGERGNVKFHKDLGLVSEVLRQDVVRKYEGDIGIGHVRYSTTGASVAENAQPLVLSY
                     VKGTLALAHNGNLVNTPELKWELIQNGAIFHTTTDSEVIAFHIARERVHSKTVEEAVLK
                     TAKKIKGAYGLVVMSPRKLIAVRDPYGLKPLCLGKRGNAYVIASESCALTSVSAEFIRD
                     IEPGEILTITKDGLKSNKELASAAAKRAHCVFEYIYFARLDSTIDGVKVYDARIRGGKS
                     LAKSYPVEADIVTGVPESGLPAAKGYSEASGIPFAFAFYKNSYIGRTFIKPTQEERESS
                     VHLKLSVLESVVKDKRIVLVDDSIVRGTTIANLIHMLKEAGAKEVHVRISSPPFLHPCY
                     FGTDVPSNDQLIAASHSTEEICKMIGADSLGYMQTDYLEGMAGGLPLCKACFDGNYPME
                     IPDYTNAEFADIVKC"
     CDS             3387..5486
                     /locus_tag="ctg30_17"
                     /transl_table=11
                     /translation="MAQNIPELYGSLVFNDKVMRSKLPKDMYKALKKTIESGTHLELDV
                     ANSVAVAMKEWATENGATHYTHWFQPMTNVTAEKHDSFISPTGDGQVIMDFSGKELVKG
                     EPDASSFPSGGLRATFEARGYTAWDPTSPAFIKDGTLYIPTAFCSYSGEALDKKTPLLR
                     SMQTLDKEATKLLHIIGNKDVKHVNTTVGPEQEYFLVDKELYKQRKDLVFCGRTLIGAP
                     APKGQEMEDHYFGALKPRVAAYMHDLDVELWKLGIPAKTKHNEVAPAQHELAPVFDTTN
                     VAVDHNQLTMEVMKKVADKHGLVCLLHEKPFEGINGSGKHNNWSMITDTGINILDPGKT
                     PAENTQFLIFLTAVIKAVDEYADVLRISVASAGNDHRLGANEAPPAVVSVFLGDELTEV
                     LKSIENDEYFAGSRAVQMDIGAKVLPHFVKDNTDRNRTSPFAFTGNKFEFRMLGSEASV
                     ANPNIILNTAVAECVHQFAEQLKDVPEDKMEDAIHELIKKTIIDHKRVIFNGNGYTDEW
                     IEEATKRGLFNLKSTPDALPQWIAEKNIELFTKYHIFTKEEIESRYEIWLESYSKILNI
                     ESNTMVEMVQKDFLPSVFAYIDKVAATAVAKKSVVSDVSTASEGKLIKELSQLADEIST
                     GLETLRADTAKALATEDPLANAKAYQTVVLSDMDELRKSVDAAETLIPDALLPYPTYDK
                     LLFSV"
     CDS             5785..7497
                     /locus_tag="ctg30_18"
                     /transl_table=11
                     /translation="MEFSAVNTIWVLVGAALVFFMQAGFAMVETGFTRAKNAGNIIMKN
                     LMDFCIGTPVFWLVGFGLMFGAGNGFIGKIGGIATEAHYGSGMLPDGVPFWAFLIFQTV
                     FCATSATIVSGAMAERTKFLSYCVYSLMISLVVYPVSGHWIWGGGFISQMGFHDFAGSC
                     AVHMVGGVAALIGAIILGPRIGKYTKDGKSKAIPGHNLTVGALGVFILWFCWFGFNGAS
                     TVSMEGDAIVSAGKIFVTTNLAAAVATVTVMIITWVRYKKPDVSMSLNGSLAGLVAITA
                     GCDTVSPTSAAIIGIASGFIVVFGIEFIDKVLKIDDPVGAVGVHGLNGAFGTLAVGLFS
                     DGSGTDWKGLLTGGGFHGFGVQFTGMIITIAWVVVTMTIIFQVIKHTIGLRVSAEEEIA
                     GLDSKEHGLASAYDGFAMAGVPTPMGTSIKAPVVTARPSAPAESVPELPKEGVHKLTKV
                     VIITRQNKLDEFMQAMNEIGVTGITITNVLGCGVQKGAPSYYRGVEMEMNLLPKVKIEI
                     VVSLVPVQKVIETAKAVLHTGQIGDGKVFVYDIENVVKIRTGEEGYLALQDTK"
     CDS             complement(7836..7994)
                     /locus_tag="ctg30_19"
                     /transl_table=11
                     /translation="MALAQATKSHEPTYTINDAMDVLLSRLDEAIDDMESDRVQIVEEA
                     WAEIDAI"
     CDS             complement(8300..8872)
                     /locus_tag="ctg30_20"
                     /transl_table=11
                     /translation="MQVSQHCFSLQKKTSGGIINVGSPTALIYTGGIHMDNNSLSHTKW
                     NCKYHIVFAPKYRRKVAYGKIKQDIADILSMLCKRKGVKIVEAEICPDHVHMLVEIPPS
                     ISVSYFVGYLKGKSTLMIFERHANLKYKYGNRHFWCRGYYVDTVGKNAKKIQEYIANQL
                     QDDLEYDQMTLKEYIDPFTGEPVKRNK"
     CDS             complement(9257..9406)
                     /locus_tag="ctg30_21"
                     /transl_table=11
                     /translation="MMIWCKKIMGGKDYEVYEKKLICSVFGHKCNSFDKFICNAGACCG
                     KYRN"
     CDS             complement(9403..9786)
                     /locus_tag="ctg30_22"
                     /transl_table=11
                     /translation="MTHKKEVVFSLLFVIMVLCTGCSDKDNGDTSKNNRTSGESFVQEE
                     TIESTDNTDNADGSSAPTPELKTPRTKKELEDALGTVNESGKWTPPAGSHIDPKTGNIL
                     NKDGVVVGTTQEPYSKARPGSQG"
     CDS             complement(10001..10585)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_23"
                     /sec_met_domain="AgrB (E-value: 2.2e-36, bitscore: 115.9,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKCTDTVVNWMIRCNAINEADKELYKYALYSFFLLVSPLILAGV
                     IGFGLGSVKHGVALIFPFVVLRKFSGGYHAKNLHTCILGSGFLLFLCIMLSMHVQCDLK
                     LAIATVIASVSLITFSPIDSENRRLDTNEKRTYKKTTVFFVILFGLLDIALFLLGKYIY
                     TICFSVGILLTAGLQVPCIVKKMCKSTKNRL"
     CDS             complement(10585..10734)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_24"
                     /sec_met_domain="TIGR04223 (E-value: 1.9e-14, bitscore:
                     44.5, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKEVTKSVAKGMKAALDVVLRTEANTASCLIMYQPKAPKELMNY
                     RRNK"
     CDS             11030..11359
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 57.2; E-value: 4.5e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg30_25"
                     /transl_table=11
                     /translation="MGNRIKIRRKELRIKQAELAERLNISNSHMSSIENGRQKPSLDIF
                     IQICNLLNVTPDYLLLGSMHAYNIPQDIIDKLRLCNQSDIELAGDFIELLVKRNNKATH
                     NEPKL"
     CDS             11451..12158
                     /locus_tag="ctg30_26"
                     /transl_table=11
                     /translation="MRILICDDDTLIIEQLKKYIESYFESNHLKCPELVSFTSGEALLT
                     DKGEKDIVFLDIEMPGMNGIYVGNELKKANRNVIVFVVTSYSEYLDEAMRFHVFRYLSK
                     PLDKQRFFRNLKDALAYYNSITLKIPVETKQAVYSFPASQIIAIEAQGRKVIVHTARQD
                     FDSIHNMNYWLEKLPQNSFFQTHRSFIVNFEHIVDFDHSTVHLSNPQITAYLTRRKYSS
                     FRNAYLLYLESMR"
     CDS             12165..13463
                     /locus_tag="ctg30_27"
                     /transl_table=11
                     /translation="MEYIILLIFSFFTEAVILWQYAASLFSPSHSGKKRLTLLSVLYVL
                     LFFLSLLGQTWLNIISFFVINTVFLYIMFNLKLLLALFHSAILTAIMGISELAVLGMIS
                     RFFPHFLLEASVGLVFYTVFSKITFFAVVYLLSWLFKGNKAAQEPYGHSEILLMFIPLS
                     SILMMFTLLSIGETTAYAPPVDFLVTICAVFLLLVNLLVFGINQYNTKRSQEYADLQLL
                     LQKESDSVEYYEMMLAQNENQSILIHDIKKHLQSIRLLNEKNDSDKINDYIQQLMESSD
                     LKETTKLCDHEMLNSILCRYQRHCNDKHIIFHTDIRSGTVQHIYPRDLTSLFCNLLENA
                     VESAENIPDSFIELTVQKKENSPFLIIILINSCQNTPVYNPEGLPISHKSDNGRHGFGI
                     KSIKKVVKQYHGNLQMYYDNDSGTFHTILTLKQ"
     CDS             13954..14466
                     /locus_tag="ctg30_28"
                     /transl_table=11
                     /translation="MRKKLNITEGIFPMPVLMVATYNEDGSINVMNAAWGTMQERDTVA
                     LNLTETHKTVQNIKARGAFTVSIADAAHVTEADYFGVESGNREPDKFARSRLTATKSET
                     VDAPIINNFPPRTKRQSDKLSLTALNITCLILYGILPIHVVTAWADSSGNVLPDIGSAP
                     LQLMILP"
     CDS             complement(14375..15028)
                     /locus_tag="ctg30_29"
                     /transl_table=11
                     /translation="MDYQSIVTFVMEMAGSVAFAASGAMVGVERNMDIFGVSVLGVATA
                     VGGGMIRDIVLGIIPPAVFTNPVYALVSVLASCIVFFIFYFKRELLQGHRRETYDKIML
                     AMDSVGLGIFTVVGVNTGIRQGYMDNVFLLVFLGTITGVGGGLLRDMMASVPPYIFVKH
                     IYACASIIGAVVCVYMNRFVGNVQAMVVSSIVVVLIRYLAAHYRWNLPRLSPHE"
     CDS             15988..17196
                     /gene_functions="other (smcogs) SMCOG1237:transposase
                     (Score: 217.5; E-value: 5.7e-66)"
                     /gene_kind="other"
                     /locus_tag="ctg30_30"
                     /transl_table=11
                     /translation="MNAVGIDVSKSKSVVAIMRPFGEIVSTPFEIKHTASDIHSLIELI
                     NSVEGESRIVMEHTGRYYEVLAHQLLEANLFVSAINPKLIKDFDNDSLRKVKSDKADAV
                     KIARYALDKWQNLKQYNVMNELRNQLKTMNRQFGFYMKHKTAMKNNLIGILDQTYPGVN
                     TYFDSPARSDGSQKWVDFASTYWHVDCVRKMSLNAFIDHYQNWCKRKKYNFSQSKAEEI
                     YGKAKELVPVLPKDAITKLIIKQAVDQLNSASTTVESLRTLMNETASKLPEYPVVMAMK
                     GVGTSLGPQLMAEIGNVSRFTHKSAITAFAGVDPGVNESGTYEQKSVPTSKRGSADLRK
                     TLFQVMDVLIKTHPQDDPVYQFLDKKRAQGKPYYVYMTAGANKFLRIYYGRVKEYLASL
                     PES"
     CDS             complement(17286..17921)
                     /locus_tag="ctg30_31"
                     /transl_table=11
                     /translation="MTYQIHENFLYLENKIFRGMDQIKQLRIYPPEKGNCKIIVVYEVS
                     GQEELPQNGHELSIDLGLHNLMTCYDSGNGKTFILGRKYLALERYFHKEIARVQAQWYG
                     QQSGKGVKYLATSKHIRKLYKRKHDSVTDYLHKVTRYLAEYCREQGITCVVAGDIRNIR
                     REKDLGHRTNQKFHSLPYNRIYIMLEYKLKRYGIRFIKQPANKKSRLN"
ORIGIN
        1 gattttttct ttgatgtcct ctgtcagctc atgttcactt ctgcacacca gtacatccgg
       61 ctggattccc attccctgaa gttcctttac gcttgcctgt gtaggttttg ttttcagttc
      121 ttcagatgcc tttaaataag gaattaatgt tacgtggatc aggattgcat tgtcatgtcc
      181 cacattgagc tggaactgac gaattgcttc caggaacggt tggctttcaa tatcaccgac
      241 tgttcctccc acctcgataa tggcaatctt gttttcctcc ggtgatttgg cgcggtagaa
      301 acggctctta atctcatttg taatatgagg aattacctgt acggtacccc cgccgaaatc
      361 cccgtgacgt tctttctgaa gaacagacca gtaaacctta ccggttgtca cattggaatt
      421 tttatcaaga ctctcatcaa tgaatctctc ataatgtccc agatccaggt ctgtctctgt
      481 accatcgtct gttacaaaaa cttctccgtg ctgaatcggg ttcatggttc cggggtcgat
      541 attgatataa ggatcaaact tctgcatggt tacctggtat cctctcgctt tcagaagacg
      601 ccccagagat gcagctgtga ttccctttcc gagaccggaa acaactcctc ctgtaacaaa
      661 tacgtatttc actgccattt tgatttcctc ctccatcatc ctttgttaat aaaaaagcgt
      721 cagatgcagc tatcagaggg cacttgaccc atctggtatt ctgcatctga cgcctttgtc
      781 agatcatcat atcttctata ataatatgtt caattggctt tctttaaaaa tatgctatac
      841 tataaaacat tttttttcgt ttgtcaataa tgaatttccc gtttttaagc aaaaacaaat
      901 caaataagtt ccttctgata aactatgaag cagttatatt ttatggaatt actctgaaca
      961 cagtcataat acagaaaaaa cgaatctgta gaagttcatc ctccagaccc gtcttctctg
     1021 cgataattat tcggttataa aaatgtaaaa tttatgcaac tgcaaatttc ttcaatgtac
     1081 gatcaaattc tcggctctcc ccgtggcagt ctactgtcag ttctctggtc agatccagac
     1141 taagtacacc aaggattgat ttggcatcaa ttaaaaatct gttgtaataa acatcaatat
     1201 caaaatcaca tctgcttgca gcattcacaa attcctgcac ctcttcagtt gcatttaact
     1261 tgattttact ctgtgacatc gtgatcaccc tttctgaaaa cattctttgt ttttttctat
     1321 cagacgccca tattatgttc cacatttcag aatttgtcaa gtttttaaat ttatccaatt
     1381 ttcataaagc gcaggggttc tattgtgcat tttgttcgtt tatatatgtt ttcacagcat
     1441 tattttatac attatgtatg acttcatcct atattggttt taccattatg tgagattgat
     1501 tccatatatc atcgacaggt ttctgcattt tttatgaatt tttgcgactt aacacttcac
     1561 aatatctgca aactccgcat ttgtataatc cggaatctcc atcggataat ttccatcgaa
     1621 gcatgcctta cataagggca ggccgcccgc cattccttcc agataatctg tctgcatgta
     1681 gccaagagaa tctgctccga tcattttaca gatttcctct gtgctgtggc tggctgcaat
     1741 gagctgatca tttgacggca catccgttcc gaaatagcat ggatgtaaaa atggcggtga
     1801 actgatacgt acgtgcactt cctttgctcc cgcctctttt aacatgtgga tcaggtttgc
     1861 aatggttgtt ccacgaacaa tagaatcatc caccagaaca atcctcttat cttttacaac
     1921 agattccagc acactcagtt tcagatgaac actggactca cgttcttcct gagtcggttt
     1981 gataaatgtt cttccaatat agctgttttt atagaacgca aatgcaaacg ggattcctga
     2041 tgcttcggag tatccctttg cagcagggag tccggactcc ggtacacctg ttacaatatc
     2101 tgcctctaca ggataagact tggcaagaga tttaccgccg cggattctgg catcatagac
     2161 cttcacccca tcaatggtac tgtcaagtct tgcaaaatat atatactcaa acacacaatg
     2221 cgcgcgtttt gcagcagcag acgcaagctc tttatttgac ttcagtccgt cttttgtaat
     2281 cgtaagaatc tcacccggct caatgtcacg gataaattcc gcacttacag atgtcagagc
     2341 acagctctca gaagcaataa cataagcatt tcctctttta ccgagacaca atggtttcag
     2401 tccatatggg tcgcggactg cgatcagttt tctcgggctc ataactacca gaccatatgc
     2461 acctttgatc ttctttgcag tctttagcac tgcctcttct actgttttag aatgcacacg
     2521 ttctcttgcg atatggaacg caataacctc tgaatctgta gttgtatgga aaatcgctcc
     2581 attctggatc agttcccatt tcagttccgg tgtattaacc agatttccgt tatgtgcaag
     2641 tgcaagagtt ccctttacat aagacaaaac aaggggctgt gcattctctg caacagaagc
     2701 tcctgttgtg gaatatctta catgaccaat accaatatcc ccctcatatt tacggacaac
     2761 atcctgtctg agaacttcac ttacaagtcc cagatcctta tgaaacttca catttccacg
     2821 ctctccctta gtatcagaaa ctgcaagtcc gcaggattcc tgtcctctgt gctgcaggga
     2881 agtcagtcca taatatatgg acggaactac attgccgcca tccagatcat aaattccaaa
     2941 gacgccgcac tcttctttta ttccagccat ctgatttcct ccgatcgtat tctcttgtct
     3001 gactttaact ttactttcaa aacccgctga cattgttttc ttatgtttga cgggttccaa
     3061 aatcaaatta taataataga aacaaatttg tcaacctatc ctttttttgc catatctcaa
     3121 aaattttttc tgaatttttt caaaaaaagt gcttgacatc tgttttcatt tcgtttatag
     3181 tacagcacat aaagcaaagg cgctttggaa agatctacag agatctcatc cagggcgctt
     3241 ttttcgtttt ataaaacttt cgtttcatag aaaatgttcg atgaggaatt ttctatgaga
     3301 cgaaaaccgc aggcagtcac aatggtgatc tgcagcggca ctacacatat tcagaaaata
     3361 ttgcaaaccg aaaggagagt acctatatgg cacagaatat ccctgaactg tacggcagcc
     3421 tggtcttcaa cgacaaagta atgagaagta aactgccaaa agacatgtac aaagcattaa
     3481 agaaaacaat cgagagcggt acacaccttg aacttgatgt tgccaactcc gttgctgttg
     3541 caatgaaaga atgggctacc gagaacggcg ccactcatta tactcactgg ttccagccaa
     3601 tgacaaacgt aactgcagag aaacatgaca gtttcatttc tcctacagga gatggtcagg
     3661 tgatcatgga tttctcaggt aaagaacttg taaaaggtga gccggatgct tccagtttcc
     3721 cgtcaggcgg tcttcgtgcc acattcgaag caagaggata tacagcatgg gatccgacat
     3781 caccggcatt catcaaagac ggaactcttt acattcctac agcattctgc tcctacagcg
     3841 gagaagctct tgataaaaag acccctctcc ttcgttccat gcagacactt gataaagaag
     3901 ctacaaaact tctccatata ataggtaata aagatgtcaa acacgtaaat acaactgtag
     3961 gtcctgaaca ggaatacttc ctggtagaca aggaattata caagcaaaga aaagaccttg
     4021 tattctgcgg acgcacactg atcggtgctc ctgctcctaa gggtcaggaa atggaagatc
     4081 attacttcgg tgctctgaaa cctcgtgttg cagcttatat gcatgacctg gatgtagagc
     4141 tctggaaact tggtattcct gccaaaacaa aacataacga agttgctcct gcacagcacg
     4201 agctggctcc tgtattcgat acaacaaacg ttgcggttga ccacaaccag ttaacaatgg
     4261 aagtaatgaa gaaagttgcc gacaagcatg gacttgtatg cctccttcat gagaaaccat
     4321 ttgagggaat caacggaagc ggtaaacaca acaactggtc tatgatcaca gatactggta
     4381 taaatatcct tgatccggga aaaacacctg ctgaaaatac acagttcctg attttcctga
     4441 cagctgttat caaagcagtt gatgaatacg cagatgtact tcgtatttct gtagcaagtg
     4501 caggaaatga tcaccgtctt ggtgcaaacg aggctccgcc tgctgttgta tccgtatttc
     4561 tcggtgatga actgacagaa gtattaaaat ctatcgaaaa tgacgaatat tttgcaggaa
     4621 gccgcgcagt ccagatggat atcggtgcaa aagtacttcc acatttcgta aaagacaata
     4681 cagacagaaa ccgtacttca ccattcgcat ttacaggtaa caaattcgaa ttccgtatgc
     4741 tcggttccga agcttctgtt gcaaacccga acattatctt aaacactgct gttgctgagt
     4801 gtgttcacca gtttgcagaa cagttaaagg atgtaccgga agacaagatg gaggatgcaa
     4861 tccacgaact gatcaagaaa acaattattg atcataaacg tgttatcttt aacggaaacg
     4921 gttatacaga cgaatggatt gaagaagcta cgaaacgtgg tctctttaac ctgaaatcta
     4981 caccggatgc tcttcctcag tggatcgcag agaagaatat tgaactcttt accaaatatc
     5041 atatcttcac aaaagaagaa attgaatccc gttatgagat ctggctggaa tcctattcca
     5101 agattcttaa cattgagtcc aatactatgg ttgaaatggt acagaaggat ttccttccat
     5161 ctgtattcgc atatatcgac aaagttgcag ctactgctgt tgctaaaaaa tcagttgttt
     5221 cagatgtcag cacagcttct gaaggaaaac tgatcaaaga gctgtcacag cttgctgatg
     5281 agatttccac aggtcttgag accttaaggg cagacactgc caaagcactt gctacagaag
     5341 atcctctggc taatgcaaaa gcataccaga cagttgttct ttctgatatg gatgaactca
     5401 gaaaatctgt agacgcagca gaaactctga tcccggatgc actgcttcca tatcctacat
     5461 atgacaagct tctgttttcc gtttaactaa caggtaataa caggggaata tctttatgaa
     5521 ctctacttca taattcatta tcgatttcct catccattaa tcacacgata ttttgatgtt
     5581 cccctgtttt acatataatt ttgattttaa actgcattgc atacagtcat acaaaatgtc
     5641 ttttctatta catcagttat gcaatacact ataaatatgg attttatatt cgcaaaagcg
     5701 cgatgaactg gctacatttc caggcattgc gctttttgca ttttataaaa tatgaggaaa
     5761 tttttatgag ggaggaatat tattatggaa ttttccgcag taaacacaat atgggtgttg
     5821 gtcggcgccg cgctggtctt ctttatgcag gccggattcg caatggtaga aacaggcttc
     5881 acacgagcca aaaacgcagg taacattatt atgaaaaacc tgatggactt ctgtatcgga
     5941 accccggtct tctggctggt cggcttcggt ctgatgttcg gtgcaggtaa tggatttatc
     6001 ggaaagatcg gtggtattgc cacagaagca cactatggtt caggaatgct tcctgacgga
     6061 gttcctttct gggcattctt aatcttccag acagtattct gtgcaacatc cgcaacaatt
     6121 gtttccggtg caatggcaga acgtaccaag ttcctttcct attgcgtcta cagccttatg
     6181 atcagtcttg ttgtatatcc ggtatccgga cactggatct ggggcggtgg atttatcagc
     6241 cagatgggat tccacgattt cgcaggttcc tgtgcagtac atatggtagg tggtgtggca
     6301 gctctgatcg gcgccatcat ccttggacct cgtatcggta agtatacaaa ggacggcaaa
     6361 tcaaaagcta tccctggaca caaccttaca gttggtgctt taggtgtatt tatcctctgg
     6421 ttctgctggt tcggatttaa cggtgcttcc acagtcagta tggaaggcga tgcaatcgta
     6481 agtgcaggta aaatcttcgt tactactaac cttgcagcag ctgttgcaac tgtaactgtt
     6541 atgatcatca catgggtacg ttacaaaaaa ccggatgttt ccatgtctct gaacggttct
     6601 cttgcaggac ttgtagcaat tacggcagga tgcgacacag tttctcctac atccgcagca
     6661 atcatcggta ttgcttccgg ttttatcgta gtatttggta ttgaatttat tgacaaagtt
     6721 ctgaaaattg atgaccctgt tggtgctgtc ggtgttcatg gtttaaacgg tgctttcggt
     6781 acccttgcag ttggtctttt ctcagacgga tcaggcacag actggaaagg actccttaca
     6841 ggcggcggct tccacggatt tggtgttcag ttcactggta tgatcatcac aatcgcatgg
     6901 gttgttgtta ctatgacaat tatcttccag gtaatcaaac atacaatcgg acttcgtgtt
     6961 tcagctgaag aagagatcgc aggtcttgac tccaaagaac atggtcttgc aagtgcttat
     7021 gacggtttcg caatggctgg tgttccgact cctatgggaa cttccataaa agctcctgtt
     7081 gtcacagcca gaccttctgc tcctgctgaa tcagttcctg aacttccgaa agaaggcgtt
     7141 cataagctta caaaagttgt tatcatcacc cgtcagaata agcttgatga atttatgcag
     7201 gcaatgaatg agatcggtgt tacaggtatc actattacga acgttctcgg atgcggtgta
     7261 cagaaaggtg ctccatccta ctatcgtggt gttgagatgg aaatgaatct tcttcctaag
     7321 gtcaaaattg agattgttgt aagtctcgta cctgtacaga aagttatcga aactgccaag
     7381 gcagtcctcc ataccggtca gattggtgat ggtaaagtat ttgtatatga cattgaaaat
     7441 gtcgttaaga tccgtacagg cgaagaaggt tatctcgcac tgcaggatac aaagtaaatt
     7501 atttatcaac aatcaggtaa tattaataag agacatcagc gtattgattg ctggtgtctc
     7561 ttattttaat ctttctttct aacaattcca atggcgttaa aaaacaggca gtatatttca
     7621 tgtaaatatc atagccacga tatcggaagc ctattgtatt atatctggta ggaagtgtgt
     7681 caagtgcaag aaccgctttt taatcttttg ggaaaaatcc tctgcatact cccggtattt
     7741 aaattgctga aggatatatt tcttttttcc ttcacatcca gcttgccgct ctgggcaatt
     7801 acaactttgt attttctttt ttccatccgt accccttata ttgcatcaat ttctgcccat
     7861 gcttcttcca ctatctgcac tctgtcactt tccatatcat caatggcttc atccagcctt
     7921 gacaaaagaa catccattgc atcattgatt gtataagttg gttcatggga ttttgttgcc
     7981 tgtgccaatg ccataaccat caccctttct tgaaatagca cttttgtttc tatttttatc
     8041 ataccacgaa ccaccggaaa tatctatata ttttaaattt gtctttataa cccaaacaca
     8101 gaatactgtt tttgggacgt tttttagaat ttgtccattt gtagtttcaa ttaaaaaagt
     8161 aaatcacgac caccggctta gccggtggtt tgctttgacc ctataagggt ctattaccgg
     8221 cactggagtc taaagactca tcgaaatagg ttcgtcaagc gcaacatcat ttacctacaa
     8281 agccctttcg ggcttatctt tatttgttac gttttactgg ctcacccgta aacgggtcaa
     8341 tatactcttt cagtgtcatt tgatcatatt ccagatcatc ctgtaactga tttgctatat
     8401 attcctgtat tttctttgca tttttcccta ccgtatctac ataatatccg cgacaccaga
     8461 aatgtctgtt tccatatttg tacttcagat ttgcatgtct ttcgaatatc attaatgtac
     8521 tctttccttt taagtaccct acaaaatacg atacacttat gcttggcgga atttctacta
     8581 acatgtgtac atgatctgga catatctctg cttcaacaat ttttacacct tttcttttgc
     8641 ataacatact caaaatatct gctatatcct gtttaatttt tccatatgct acttttcttc
     8701 tatattttgg tgcaaaaaca atatgatact tacaattcca ctttgtatgt gataaactat
     8761 tattatccat atggatacct cctgtgtata ttagtgcggt tggcgaacct acattaatta
     8821 taccaccgga ggtttttttc tgtaagctga agcaatgctg actcacctgc atagcaggtg
     8881 gtttatttgt tttccaaagc tccgtttttc ggatcagcga aaaactccac aatggcaaac
     8941 agggctttgc cctaacaaca aaagtgctgc cgcaccaaac ttttcagtgc ggcagcccat
     9001 acagctattt acctatgcct cgtttatatt aaatgttttt ccttaaagct cccgaaggta
     9061 atcggcacta acataacggt aaatgccgcc aagagaaatt ttggcccacc cattactgat
     9121 agaatataca tatacttttg tgccataatt caatgtgcct actattgtat attgtgttcc
     9181 agggcctgat ctgatattta catccgaccc tgtgcacttg taatatcccg gtacgcttct
     9241 cgtgacagag cttgtttcaa ttcctgtatt ttccgcagca agcaccggca ttgcaaatga
     9301 acttgtcaaa agaattgcac ttatgaccaa acacactaca aatgagtttt ttctcatata
     9361 cttcataatc ttttcctccc ataatttttt tacaccatat catcatcctt gagaacctgg
     9421 acgtgcttta ctataaggtt cctgcgtagt tccaaccacg accccatctt tattcagtat
     9481 attacctgtt ttgggatcta tatgagaacc ggctggtggc gtccattttc ccgactcatt
     9541 cactgtacca agcgcatctt ccaattcctt tttcgttcgg ggcgttttca gttctggcgt
     9601 tggtgccgag ctgccgtctg cattgtctgt attgtctgta ctctcaatag tttcttcttg
     9661 aacaaatgat tctcctgaag tcctgttatt tttagacgta tctccattat ctttatcact
     9721 gcagcctgta cataacacca ttattacaaa caacaagcta aaaacaactt ctttcttatg
     9781 tgtcatttta atcttttacc tccattatgc ccgtttaact actccgaacc gaactactca
     9841 atttaaagtg atagaattct atcattgtcc cattggaatc cactcccttt caatgaacaa
     9901 actgaattaa ctgtaaataa agaactttga tcaaatcaat gacaaacttt attatcttta
     9961 tttttgccat gatttcaacc ccttttgcac caaacgacat ttacagtctg tttttggtcg
    10021 atttacacat tttctttacg atacaaggta cttgtaagcc tgctgtcagt aatatcccaa
    10081 cagaaaaaca gattgtatag atgtactttc ccagcaaaaa taaagctata tctaacagcc
    10141 caaacagtat cacgaagaac actgttgttt ttttatatgt ccttttctcg ttagtatcaa
    10201 gtcttctgtt ttcactgtct attggactaa atgtaatcag gctcacagac gcaataactg
    10261 tagctattgc caacttcaaa tcacattgca catgcattga taacattatg cacagaaaca
    10321 atagaaaacc agatccaaga atacaagtgt gcaaattttt tgcatgataa ccaccactaa
    10381 attttctcag aaccacaaac ggaaaaataa gagcaactcc gtgttttacg cttcccaagc
    10441 caaagccaat aactcctgca aggataagtg gtgataccaa tagaaaaaaa ctatataatg
    10501 catacttgta aagttcctta tccgcctcgt ttatcgcatt acaccggatc atccaattta
    10561 ctactgtatc tgtacatttt tccattactt gtttctcctg tagttcatta attctttcgg
    10621 tgccttaggc tgatacatga taagacaaga agctgtgtta gcttctgtcc gtaacacaac
    10681 atctaatgct gctttcattc cttttgcaac cgatttagtt acctctttct tcataatgac
    10741 ctctctcctt tccactaaaa tttgtcattg attttcacat aagcaatcat ataccacttt
    10801 aatcaaataa acgacccctt tggaatgaac ggaatgattc tttacaatat tggataattt
    10861 ccctcttttc tacgaaaaat aatatgtgat acagaattat ttatatataa atatcagttt
    10921 gtttaatata ttgcagaata gttctttgtt acattcttct ttttatttag ttctattggt
    10981 aaaattctac tgaaagaagg tgggataaat agaatttcaa tatgaaggta tgggaaaccg
    11041 catcaaaata cgcagaaaag aattacggat aaaacaggca gaacttgccg aaagattaaa
    11101 tatatccaat agccatatgt catcaatcga aaacggaagg caaaaaccaa gtctggatat
    11161 tttcattcag atttgtaatt tactcaatgt tacacctgac taccttctgc tcggcagtat
    11221 gcacgcttat aatattccac aggatattat tgataaacta cggttatgta atcaatccga
    11281 catagagctt gccggagact ttatcgaact gcttgtaaaa cgaaataaca aagcaacaca
    11341 taatgaacca aaattgtaat taaattgtct tttcatacgc attttttgca tttggaaatt
    11401 ctatgtgata agatgtacac atacatctat ttagaaagtc aggtgaaaaa atgcgtattt
    11461 taatttgtga tgatgacact ctgatcattg aacaattgaa gaagtatatc gaatcctact
    11521 ttgagtccaa ccatttaaaa tgtcctgaat tagtttcttt taccagtggt gaagctttgt
    11581 taactgacaa aggtgaaaag gatattgttt ttctggatat cgaaatgcct ggcatgaatg
    11641 gaatctatgt tgggaatgaa ttaaaaaaag caaatagaaa tgtgatcgtt tttgttgtca
    11701 cctcttattc tgaatatttg gatgaagcaa tgcgttttca tgtattccgt tacctttcca
    11761 aacctctaga taagcagcgt tttttccgaa atctgaagga tgccttagct tattacaatt
    11821 ccattacact caaaattcct gtggaaacaa aacaggcggt atattcgttt cctgcttcgc
    11881 agattattgc catagaagct caggggcgaa aagtaattgt acatactgcc cgtcaggact
    11941 ttgactctat tcataatatg aattactggt tggaaaagct tccccaaaac agtttttttc
    12001 agacacaccg gagctttatt gttaacttcg aacatattgt ggactttgat cactccaccg
    12061 tacatttatc aaatcctcag attaccgctt acctgacacg caggaaatac agttccttca
    12121 gaaatgcata tctactatat ctggaaagca tgaggtgaaa ataaatggaa tatattattt
    12181 tacttatttt tagttttttt acagaagcgg ttatcttatg gcagtacgcc gccagccttt
    12241 tttccccttc tcatagcggt aaaaagagac tgactctatt aagtgttctt tatgtactgt
    12301 tgttttttct ttccctgctt gggcaaacat ggctgaatat tatcagtttt tttgtgataa
    12361 acactgtttt cctctatata atgtttaacc tcaagttatt attggcactc ttccattccg
    12421 ctatacttac agcgattatg ggaatatctg aacttgcagt tttggggatg atatcaagat
    12481 tctttcccca ttttctctta gaagcaagtg tcggacttgt tttttatacc gtatttagca
    12541 aaattacctt ttttgcagtc gtttacttgt taagttggct cttcaagggg aacaaagcag
    12601 ctcaagaacc gtacggtcac tccgaaattc tcttgatgtt catcccgctt tcctctattc
    12661 ttatgatgtt tactcttctt tctattggtg aaacaaccgc atatgcccca ccggttgatt
    12721 ttctagtaac aatctgtgcc gtttttctgt tgctggtcaa cctacttgta tttggaatca
    12781 accaatataa cacaaaaaga tcacaggaat atgccgattt gcagttactg ctccagaaag
    12841 aatccgattc tgttgaatac tatgaaatga tgcttgcaca aaacgagaac cagagcattt
    12901 tgatccacga tataaagaaa catcttcaat caatcagatt actgaacgaa aaaaatgatt
    12961 ccgataaaat aaatgactat atacaacaac tcatggaatc ttccgactta aaggaaacca
    13021 caaaactctg tgatcatgaa atgctaaact ccattctgtg ccgctatcag cgccactgca
    13081 atgataagca cattattttt cacactgaca tcagaagcgg cacggtacaa catatatatc
    13141 cgcgcgattt gacttcttta ttctgtaact tattggagaa tgcagtggaa tcagcagaga
    13201 atattccaga ctcttttatt gagctcaccg tacaaaagaa agaaaattca ccctttctta
    13261 ttatcatact catcaactcc tgccaaaata cccctgtata taatccagag ggacttccta
    13321 tatcccataa atcagacaat ggcagacatg gattcggaat caaaagcatt aaaaaagtcg
    13381 taaaacagta ccatggaaat ttgcaaatgt attatgataa tgattccggt accttccata
    13441 caatcctaac cttaaagcag taaatattaa aatctggcaa tcgcaatttt atacgattgc
    13501 ctttttacat atttcagcat gcattgatgt tgttttatat cactataaat gagcaagttc
    13561 gtgattttgc ataaaagaaa gagatctttt cctgttatgt gtgtcgatgg ccgatcgaga
    13621 tatttttcag gcaatgtaaa aaccgtctgg cactggatac ataccagatc cgtttctcaa
    13681 aggaaataca gagatactgg ctgctgatgt cactggcaca ttgtatttgt gtcacaggaa
    13741 ctggcaaata tcgatctttt caagatggat atcatcgaat ctgtagtgcc gttcatcagg
    13801 aaaagtatca gtatctattc ctatgtgcaa aagcaagtga tgattttgaa gcatttatga
    13861 aattagcagg ataattttgt gcattttttc aaacttgctc atttatagca ggatatatta
    13921 tcctgtcaat tgaatctgaa aggggctgtt gtaatgagaa aaaaattaaa tattacagaa
    13981 ggcatttttc ctatgcctgt attgatggtt gcaacctata atgaagacgg aagcatcaat
    14041 gtaatgaacg ctgcctgggg tacgatgcag gaacgtgaca cagttgcatt gaaccttacc
    14101 gagacccata aaaccgtaca gaatatcaaa gcacgcggtg catttaccgt cagcatcgcg
    14161 gatgccgcac atgtaacaga agctgactat ttcggtgtag aatccggtaa tcgcgagcct
    14221 gataaatttg cccgcagccg tctgaccgcc acaaaatctg aaactgtaga tgctccgatt
    14281 atcaataatt ttcctcctcg aacaaaaaga cagtcagaca aactcagcct gactgcgcta
    14341 aatattacct gtctgatttt atacggtatc cttcctattc atgtggtgac agcctgggca
    14401 gattccagcg gtaatgtgct gccagatatc ggatcagcac cactacaatt gatgatacta
    14461 ccatagcctg tacatttccc acaaatcgat tcatatatac gcatacaact gcaccaatga
    14521 tggaggcaca ggcatagata tgttttacaa aaatatacgg cggtacactc gccatcatat
    14581 ctctaagcag accgccgcct actcccgtaa tggttccaag aaatacaagc aggaacacat
    14641 tgtccatata tccctggcgg attcctgtat ttactcctac tactgtaaaa atcccaagcc
    14701 cgacagagtc cattgccagc atgattttat cgtaggtctc acgcctgtgc ccctgaagca
    14761 attctctctt gaaataaaaa ataaagaaaa caatgcagga agcaagcact gacaccagtg
    14821 catatacagg attggtaaat acagccggag ggatgatccc cagaacaata tccctgatca
    14881 ttcctccgcc tactgctgtt gcaactccca gaacgctcac gccgaaaata tccatattcc
    14941 gttcaacgcc caccatcgct ccggaagcag caaacgccac tgaaccggcc atttccataa
    15001 caaatgttac aattgactga taatccatat ttgtttttta actccccatc ctatctttct
    15061 tttataatcc cagaaaacaa tgcaactaat gcactcctgc aaagcacgaa agacaggaaa
    15121 atgctgaact gtcttaattg cattattttc tggaattgct ataaaaatat cagtaaatct
    15181 ccgttcatca cttaatgttt tcataattga agcaggagat tccactgaat tatccaagat
    15241 aaaaagtcga ttttttgaac gtcacgtgaa agagtcttta ctctcaatca gtatcagaaa
    15301 atcgactatt tattccattt catatagata aacttatata cttcgcgaac accttcagca
    15361 tagtatagta agtgaattac tcggcaactg agttaccaga gcatctgaat taaggcggga
    15421 taccgccttt ttttcagggt gcatccatga caccactact gtttgctctt tagagctata
    15481 cagctacttt tattatttcc ggtgttttca gtccggttac ggacagttct ttttttactc
    15541 cggatacgga gtgatatttt ctcaggatat tatatgcgcc tacggcatct gcgttatagg
    15601 ttctgtttcc atctctgtac aaccctctct ctttccgttt ggacggctct gcatatcttt
    15661 tccccacttt cggtgacagc ggactgcact ggctggtata actttcttcc tactacaata
    15721 tatttatggt taatatccct tacatccagt aaggaattat ccatcttgtt gcttaagctg
    15781 ttagaatgta ggtagcaatt ggatatcttt ttcttccttg gacttcgcgt ccgtaaaaca
    15841 gactgataac cagttcctca ttcgcagcgt tcgttttatg caggttgaat caccttaggt
    15901 gcattcgtgt cacaccacag tagattgaat aggcaatgag taaaactggt acttatccat
    15961 tgcaataatc ttaaggagtg acaatttatg aacgcagtag gtatcgatgt ttctaaaagt
    16021 aaaagtgtgg ttgctattat gcggcctttc ggtgaaattg tttccacacc tttcgaaatc
    16081 aaacacacag ccagcgatat ccattcactt atagaactca tcaactctgt tgaaggtgag
    16141 tctcgaatcg taatggagca cacaggacgt tattatgaag tcctcgctca tcagcttttg
    16201 gaggcaaatc ttttcgtcag tgccattaac ccaaaactta tcaaagactt tgataatgat
    16261 tctcttcgta aagtgaaatc tgacaaagcg gatgctgtta agattgcccg atatgctctt
    16321 gacaaatggc aaaaccttaa acagtataat gttatgaatg aattacgcaa tcagctcaaa
    16381 accatgaatc gccagttcgg cttttacatg aagcataaga cagctatgaa aaataatctt
    16441 atcggcatcc ttgaccaaac ctatcctggt gttaatactt actttgacag tcctgcacgc
    16501 agtgacggca gccagaaatg ggttgatttt gcatctacat actggcatgt ggactgtgtc
    16561 cgtaaaatgt ccctgaatgc ctttatcgac cattatcaaa actggtgcaa acgcaagaag
    16621 tacaacttca gtcagtcaaa agctgaagaa atctatggaa aagcaaagga acttgttcct
    16681 gtacttccaa aggatgccat tacaaagctt attatcaagc aggctgtaga ccagcttaat
    16741 agtgcctcta caactgttga gtcactacgc actctcatga atgaaactgc atccaaactc
    16801 ccggagtatc ctgtcgttat ggctatgaaa ggtgttggaa cttcacttgg tcctcagttg
    16861 atggctgaga ttggaaatgt ttcccgtttc actcacaaaa gtgctattac tgcatttgcc
    16921 ggtgtagatc ccggtgttaa tgaatccgga acctatgaac aaaaaagtgt tcctacctca
    16981 aaacgaggtt ccgctgatct aagaaagact ttatttcagg taatggatgt cctaattaaa
    17041 acgcatcctc aagatgatcc tgtttatcag ttcttagata agaaacgtgc tcaaggcaag
    17101 ccttactatg tctatatgac tgcaggtgcc aacaagtttc taagaatcta ctacggacga
    17161 gtgaaagaat atctcgcatc tcttccagag tcttaattat ccaccaaaat tttcagacca
    17221 gcactggcgt ggtggtctaa ttttgatacc caattttcaa cctgtataaa tttttcaata
    17281 ttctttcaat ttagccttga ctttttattt gcaggctgtt ttataaaacg gatcccatat
    17341 cttttcagct tatattccag catgatgtag atcctgttat acggcaggct gtggaacttc
    17401 tggtttgtcc tgtgtcccag gtctttttct ctccggatat tccggatatc ccctgcaacg
    17461 acacaggtga tcccctgttc ccggcagtat tctgcaagat accttgtgac cttgtgcaga
    17521 taatccgtta ctgaatcatg ttttctctta tataacttcc tgatatgttt tgatgtagcc
    17581 agatacttta ctccctttcc ggactgctgc ccataccact gggcctgcac ccttgcgatc
    17641 tctttatgga aatatctttc cagtgcaagg tacttcctgc ccaagataaa cgtcttaccg
    17701 ttcccggaat cataacacgt cataagatta tggagtccca gatcaatgga cagttcatgt
    17761 ccgttctgtg gaagttcttc ctggccagaa acctcataaa caacaataat tttacagttt
    17821 cccttctccg gcggatagat ccgcagctgt ttgatctgat ccatgcccct gaaaatctta
    17881 ttttcaaggt aaagaaagtt ttcatggatc tgatacgttt ctt
//
