LOCUS       c00022_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ODLGFHOP_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:43:48
            Original ID  :: gnl|Prokka|ODLGFHOP_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 45874
            Orig. end    :: 69123
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[55874:59123]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1415..2872
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_44"
                     /sec_met_domain="FGGY_C (E-value: 1.2e-37, bitscore: 123.0,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 7.9e-80, bitscore: 261.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARNLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(2984..3919)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg22_45"
                     /sec_met_domain="LysR_substrate (E-value: 5.9e-33,
                     bitscore: 107.5, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 6.8e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFERYIYQKEQ
                     LLLAVPKNYSVNTRLQKYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4035..5459
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_46"
                     /sec_met_domain="Lyase_1 (E-value: 4.3e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 1.6e-21, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5568..7253)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_47"
                     /sec_met_domain="FTHFS (E-value: 8.1e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_48"
                     /sec_met_domain="OKR_DC_1_C (E-value: 4.6e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 1e-125,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_49"
                     /sec_met_domain="Spermine_synth (E-value: 1.6e-52,
                     bitscore: 171.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 8.5e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYTALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_50"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 7.1e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 7.4e-35,
                     bitscore: 113.6, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKIDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKKAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_51"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 3.6e-14,
                     bitscore: 46.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTGASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_52"
                     /sec_met_domain="PAD_porph (E-value: 9.5e-128, bitscore:
                     419.4, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGTFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTRED
                     VDGFVFEEGEDERETGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14488..15366
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_53"
                     /sec_met_domain="CN_hydrolase (E-value: 3.3e-55, bitscore:
                     180.7, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGVYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15594..16055
                     /locus_tag="ctg22_54"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIVLLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             16259..20956
                     /locus_tag="ctg22_55"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFVLQAILGLVPVCETQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLRSFVVQDILEDC
                     LTIEDASKISIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHVSMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQLLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARSVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVAEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLNVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGETETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEVVFKTESTEPEKIVNTAKA
                     RGDISPEIAAQQEVYVKTKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGNGGSSYGNSGGYGSYQGGSMAGSS
                     KTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKDMPRK"
     CDS             20953..21840
                     /locus_tag="ctg22_56"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             22032..23123
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_57"
                     /sec_met_domain="Peripla_BP_3 (E-value: 1e-32, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
ORIGIN
        1 tggaaacttc ggacctgaaa ctcctgaaac tctgatcgca gagagatttg acggaccttg
       61 tatgtatgta gcagcagcag aaggtgacgg tgatatgatc aacggcagag gtgatgctta
      121 ctgtggtatg cttaactgct cctacaactt aaaaatgcgt catctgaaag catatattcc
      181 ggaatatcct gttggaacag cagatgatat tgcaaagatg atcgctgatt tcgtaccggt
      241 tgcacgtgca gtcatcggtg tcagcaatct taagatcatt actttcggac cacgtccaca
      301 ggacttcttc gcatgcaacg cacctattaa aggcctctat gagctgggtg ttgagattga
      361 agagaactca gagcttgatc ttcttgtttc tttcaaagag catgaaaatg atcctcgtat
      421 cccggaagtt tgtgcagata tggcaaaaga gatgggcgaa ggcaaatatt atgctgacct
      481 taatgtgaaa atggcacagt ttgagcttac acttcttgac tgggcagagg ctcataaggg
      541 agcaagaaaa tacgttgcat ttgctgacaa atgttggcct gcattcccgt cacagtttgg
      601 atttgaacct tgctatgtaa atagccgtct ggtttccaga ggaattccgg tatcctgtga
      661 ggttgatatc tacggagcac tcagcgagta catcggactt tgcatttcca atgatgcagt
      721 tacactgctt gatatcaaca actctgttcc acagtatatc tatgatgaag atattaaagg
      781 aaaatacgat tataagctta ctgatacatt tatgggattc cattgtggaa atactcctgc
      841 atgcaagatg tgtgattcca gagctgttaa atatcagctg atccagcaca gacttcttga
      901 gccggcagga tctgaaccag acttcacaag aggaactctt gaaggtgata tcgctgcatc
      961 tgacattaca ttctatcgtt tacagtgcaa ttccgagggc gagctggttt cttatgttgc
     1021 agaaggtgaa gtactggatg tacctacaag atcattcggt ggtatcggta ttttcgcaat
     1081 caaagaaatg ggaagattct accgtcacgt actgatcgag ggcaactatc cgcatcatgg
     1141 agcagttatg tttggacatt acggaaaagc attctatgag gtagtgaaat tccttggact
     1201 ggatgttaag aagattggat ataaccagcc ggcaggcgta agatacccga cagaaaatcc
     1261 atggggttaa tgagaaatca gtaaaacgga ttattaatgt tcatgtgaag tgaatgaatc
     1321 tgaatacaga ataaataaac tgacactata ttaaaggcat cccggggctt tgctctggga
     1381 tgtattagat tagaaataga aaaggagagc acttatgtat tatattggta ttgatcttgg
     1441 tacttccgct gtaaaacttc ttcttatgga agaatcagga aaaatctgta acatcgtatc
     1501 cagagaatat cctttattct tcccacatcc gggctggtct gagcagaaac cggaagactg
     1561 gtttgcgcag agtatggaag gcatgaaaga gctgacaaag gatatcgaca gagcgcaggt
     1621 agcaggaatt ggttttggcg gccagatgca tggtctggta acacttgaca aggatgataa
     1681 tgtgatccgt cctgcaatcc tctggaatga cggacgtaca ggcgaagaga cagaatatct
     1741 gaatacagtg atcggaaaag acaaactttc acagtataca gcaaatattg ctttcgcagg
     1801 cttcacagca ccgaagatcc tctggatgca gaaaaatgag cctgagaact ttaagaaggt
     1861 agtaaagatt atgcttccta aggattatct ggcatatcgt ctgtctggtt ctttttgtac
     1921 agatgtttct gatgcttccg gtatgcttct tcttgatgtg aagaaccgct gctggtcaaa
     1981 agaaatgttg gagatctgtg gaatcacaga agagcagctt ccgaaactgt atgagagttg
     2041 ggaagtagta ggaactctga aacctgagat tgcgaaagaa cttggattca gtgagaatgt
     2101 aaaagttgtt gcaggtgcag gtgacaatgc ggcagctgct gtaggaacag gtacagttgg
     2161 tgacggtcag tgtaatattt ctcttggaac atccggaact gtgtttattt ccagtaaaaa
     2221 ctttggtgtg gacgaaaata acgcacttca ttctttctgt catgcagatg gaagctatca
     2281 tctgatggga tgcatgctca gcgcagcttc ctgtaacaaa tggtgggcag aggagattct
     2341 tcagacaaag gatttcgcag cagagcaggc tccaattcag aagctgggag agaatcatgt
     2401 attcttcctt ccatatttga tgggagaacg ttcacctcat aataatcctg atgcaagagg
     2461 tgtattcttc ggaatgtcca tggacagcac aagagcagac atgacacagg ctgttctgga
     2521 aggtgttgcc tttggtcttc gtgattccct ggaagttgca agaaaccttg gaatcaagat
     2581 tgagagaacc aagatctgcg gtggtggagc taagagccca ctgtggaaga agatcattgc
     2641 aaacgttatg aacctgaagg ttgatgttct ggagaacgaa gaaggaccgt ccatgggtgg
     2701 agctatgctg gcagcagtag gctgtggtgc ttacccggat gtagaaacca tcggtaagaa
     2761 atttgccaaa gttgttgata cggtagaacc ggatcctgaa ctggttgcaa aatatgaaga
     2821 gagatatcag aagttcagaa ctctgtatcc ggcgatgaag ccattgttct aatcgaatat
     2881 ctgcctgaca tactggggtt gttgtgctta tttagcacaa caaccccatt ttgacgtaca
     2941 tctgatgatg accaatcacc atagcctatt tgattatgac atatcaggaa aagggcagct
     3001 tcaggaattc ttccatggct ctgctgatat agcggccttt cttccagtaa aaaaacacag
     3061 tgcgtttact gctctgaccg ggcagcttat aaaaaacaag ttctgaattt gttggaactc
     3121 tggagagcag aagatccccg atgaaagtga tacccattcc caaacatgca atattatagg
     3181 cagtcatctg ctgatctagg cgaaatacta cagaaggcga aaagtgattt tcctgacaaa
     3241 tggtaagtgc acgcttaccg gtatcattat ctgaacgaag aataataaat ggttcgttct
     3301 cgaatttgtt taatggaaca gaaggaatat gagaagaacg gaactgcccg ttccggattt
     3361 cctcaatagg aatctgatat ttctgcagtc tggtatttac tgagtaattt ttgggaactg
     3421 caagaagaag ttgttctttc tggtagatat aacgttcaaa aatctggtta tccagaatac
     3481 agttatcaat caccagatct aactttccgg cctggagaaa ctgggatagt tttgctgtac
     3541 tttcttctac aagagaaatt tgaacatggg ggaatttttg ggaaaaatca gcaataaggg
     3601 gaggcagaat ccacgaagaa aaaaagttac tgccacctac attaagagtt cctgttttga
     3661 gatttcccag atccagtagg tagttttcga gattattttc aatatccatg actttttcaa
     3721 cagcctgtat ataatgtttt ccaacttcag ttaactgcaa aggtttggta cttcgatcaa
     3781 aaataggata gccaatacgg ttttccacac gttttacatt ggcgcttaaa gaaggctgcg
     3841 aaatgaaaag agcagcagca gctttggaaa agcttttttc cttgtagacc tcatagatgt
     3901 attccattcc ctgaaacata taaactcctc cgatatataa tttaaacact atatatttta
     3961 taaaaatata tgtatttgat tatattatag cagagatata taatgagggc aaatacatgg
     4021 gagggcgaat aactatgaaa aaaacagact atcgtgtaga aagggattct attggtgtaa
     4081 aggatattcc ggaagatgta tattatggag tacaatcctt acgtgcggct gaaaatttcc
     4141 acattacggg gctgaatatg catccggaaa ttattaacag tcttgcatac ataaaaaaag
     4201 cagcagcgat aaccaattgt gaggtggggc ttcttgagaa gaaaaaagca caggcgattg
     4261 tccaggcatg tgatgaaatt gtttcaggaa aattccataa tgaatttatt gtggatcctg
     4321 ttcagggagg agctggcaca tctttaaata tgaatgccaa tgaagtaatt gcaaatcgcg
     4381 cgattgagat actgggagga aaaaagggcg attatacaat tataaatcct aacgatgatg
     4441 tgaattgtgg acagtctacc aatgacgtta ttcctactgc cggtaaaatg acttctcttc
     4501 gtttgttgca gaatctgaaa aaacagcttc ttcgcctcta tgatgctctt aatgaaaaag
     4561 ctacagagtt tgatcacata ataaaaatgg ggcgtacaca gatgcaggat gcagtaccaa
     4621 ttcgtctggg acaggaattt aaggcatatt cggtagcaat catgcgtgat atccacagaa
     4681 tggataaagc aatggatgaa atgcggactc ttaatatggg aggtactgct attggaacag
     4741 gaattaatgc agatgagggc tatctgagaa gaattgttcc aaatctcact gaaatatcgg
     4801 gaatggactt tatacaggct tttgatctga ttgattccac tcagaatctg gatccatttg
     4861 tagccgtttc cggtgctgtg aaagcatgtg cggtaactct ttccaaaatg tcaaatgatc
     4921 tccgtctgat gtcctccggt ccacgtactg gttttgggga gattaatctt ccggcaaaac
     4981 agaatggttc ctctattatg ccaggtaaag ttaatccggt tattcctgaa gtagtgaatc
     5041 aggttgcttt taatattatt ggtaatgatg ttaccattac catggctgca gaggctggtc
     5101 agctggaatt aaatgcgttt gagccgatta ttttctattg catgttccag tctatcgata
     5161 ctcttggcta tgcagtccag acattggtgg ataattgtat tgtaggaatt acggcaaatg
     5221 aagaaagatg ccgttatctg gtagaaaaca gtgtaggtat tatcactgca atcagccccc
     5281 atcttggata tcagaaggct gcggatattg caaaaaaggc aattaagaca ggcgaatctg
     5341 taagaagtct gattctgaaa gaaaagctta tggacgagga tgaacttaat cgcattctgg
     5401 atccgatcca tatgacggaa cctggtattt ccggaaaaga ttatcttata aaaaaataaa
     5461 gaaaaaaaca ggcgggaaaa tcttcccgcc tgtaaaatcg tctggacaca tatcatatat
     5521 aaatatgatt tttatatttt tgaattattc gattgatttc aaccggatta gaacagacct
     5581 gtgatcttac ctgtctcgtc tacgtcgatt ctctcagcag ccggaacttt aggaagacct
     5641 ggcattgtca tgatctcgcc tgtaagagct acgatgaatc ctgcaccagc ggaaatcttc
     5701 aggttacgta ctgtaacttc aaagtcagta ggagcaccca gtttggtctg gtcatctgtt
     5761 aagctgtact gagtcttagc tacacagatc gggcagttgc cgaatccaag agcttctaac
     5821 tgtttcgcct gtttctgagc gttagctgtc agaactactt tcttaccgcc atatactttc
     5881 tgaacgatct ggttcagttt gtcttcgata gaaccttcca gttcatatgc ataggagaag
     5941 tcgtttggtt cttcaacaag acggataact tcttctgcaa gtttgattcc gccttcgccg
     6001 ccttttgccc atacttcaga aagagcaacg ttaacgccca gttctttaca tttagcttct
     6061 acaaagtcaa gctctgcttt tgtatctgta gggaatgcgt tgatagcaac aacacatgga
     6121 agtttgtata cgtttttgat gttggaaacg tgttttaaca ggttcgggat acctttttca
     6181 agagcttcca ggttttcatt gttaaggtca gctttagcaa cgccgccgtt gtatttcagg
     6241 gcacgtactg tagctacgat tacaactgcg cttggtttta aaccagccat acggcatttg
     6301 atatcaagga atttctcagc accaaggtca gcaccgaaac cagcttctgt gattgcataa
     6361 tcagcaagct tcatagccat ctttgtagct gttacagagt tacatccatg agcgatgttt
     6421 gcgaatggtc cgccatgtac gattgcagga acgtgttcca gagtctgtac aaggtttggt
     6481 ttcagagcat cttttaacag ggctgtcata gcgccttctg cgtgaaggtc acctgctgtt
     6541 acaggtttct gctcggaaac ttttccgtat gtatatccga tgatgatctt ggataatctt
     6601 tctttcaggt ctttgatgtc gcttgcaaga cagagaactg ccatgatttc agatgcaact
     6661 gtgatgtcgt atccgtcttc acgaggcata ccgtttgtct ttccgccaag accatctact
     6721 acgttacgaa gctgacggtc gttcatatct acacatcttc tccatgtgat cttacgtggg
     6781 tcgatgttta atgcattgcc ctggaagata tggttatcga tcatagctgc cagtaagttg
     6841 ttagctgcgc caatggcatg gaagtcacct gtgaagtgaa ggttaatatc ttccatagga
     6901 acaacctgtg catatccgcc gcctgctgca ccacctttta caccgaatac cggtcctaag
     6961 gatggctcac gaagagctac cataacactc ttgccaagtc tctgcatacc atctgcaaga
     7021 cctacagtag tagtagtttt accttctcct gctggagttg ggttgatagc tgtaacgagg
     7081 attaattttc catccttctt atcactttct ttcagaagat tgtagtcgat ttttgctttg
     7141 tattttccgt actgctccag atatttgtcg tcaatacctg ctttctctgc gatctgagta
     7201 attggaagca tctcgcattc ctgtgcaatt tcaatgtctg atttgaatcc cataattgtt
     7261 tttctccttt cgtttccgca taacatgaaa aacttctgtt gctgttcact ccgcgatcag
     7321 caacaattat taattgaaag aagtattggc cggtctgcct ggtattcctg atttctgccc
     7381 tgaaagttat aaaaaaaggc cagtatctga atatttcaaa tactgcccag acggtcggct
     7441 cccacaaacc tccgactcca cgtggtttgc actccactct ttccgtcagt actcgaaggt
     7501 tctttcaatt gatgaataca atatatcatt ttgagaaaaa aatgtcaaga aaattttgtt
     7561 gaaacgtcaa aaaatgtgag taaactggat aaaagttgtg caaattgata agagaagaga
     7621 atcgtaatcc ctggtcatga aagaaaatac gttttctcaa ggaaagaaat tgttaaaaaa
     7681 taaacacagt tttccctgat aaatgaagaa aatataaaaa gcgggtaaag ctagagcgtg
     7741 tctgaaaaat cattcccgca atctgtacgc ccccactttg cgggatattt cacccgaatt
     7801 cagttgccgt agcccgctac ggcgccctca tccgggcaaa atatcccaca aattgtgacg
     7861 cacatcttgc agaaagcctt tttcagacac gctctagtgc aaaatatgga aaatggaatt
     7921 gacaacagtt cagaagatat gttattctca tctttagtat gaaaagacac tatcgttttc
     7981 atgcaaatat ttgctcacat tcagagacag tttctgaatg ttaagccata cggacaggcg
     8041 gggcagttgc cgggtgggag acaccacatt attgattgag ttagaagctc aaattttata
     8101 agttgattac tttataataa tcagtgcgta agcacacatc atcttgtgaa acggtcaata
     8161 agagcatagc atatatttgc cagcgattga agacgacagc agtcatgaat atttcagaat
     8221 acgggaacag gcacaggata cagacggatt tatacgggaa atccggtcag tatataaaga
     8281 gacagagcct gagaaattct atagatcatg agagaagcag atggtgaatg aacttatctg
     8341 cttctttttt gtgcagatat agcaaatata aaggatatgg ttggagataa acgctttgcg
     8401 aggatgtgtc tcacatgcgt tcgacttgaa tatatagaga aataattgaa tcattgtgcc
     8461 ggtttgaggc agtatacaat tgctgaatga tagaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccagagctt gcacagttgc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc atccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcgc atgcattcct tatggtagga ggaaccacat
     8821 ctgcagtgca gagcatgatc ctgtctgtct gcaaggcagg ggataagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg cggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgcg cagctgggca tttcccttgg catggaagtc agccaggtgg
     9001 agaaggctat ggatgagaat ccggatgcgg tggcagttct tgtaaataac cctacctatt
     9061 atggaatctg ttcggatctg cggactatcg taaagaaggc tcatgcaaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtatccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agcgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcacttagg ggagaggaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gttattatgc atatggcatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc catttataca ctgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccatcgg agacaggctt caggatattg
     9661 agagactggt aggggcattg gctgatattg aacgtctgta taagaaggac agtacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctggaga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaaca tcttcaggtc ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtattct ctgataaaga tgaatttatt tatgatgaga tggttacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg atcatcggcg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtggaatc
    10321 cgataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttatac ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggtggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaacagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaagatagat
    11041 gcggataatg cagcagaggt cgcagaattg attagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctacgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgagaaatt taagaaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgcc tatgccctga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaacggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct acgatttccc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa aaatattccg
    11641 ggagtacaga ggatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaatgg acaggagatc
    11761 gtgccgattc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgattgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttccg gctttgctct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatagag gaactggatc ggatctgtga
    12421 ccatattatc tttaattcca cagcacagct gaagaaattt aaagaagtgt gtaccggagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg cgatctatga
    12541 tccctgtgcg ccgggttcca ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatc gacggactgc attttcatac gctctgcgaa cagaatgcgg atgatctgga
    12661 gaaaaccttg caggcggtag aggagaagtt tggagaattt ctgtctgagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatgagat
    12901 cagaacgctg attctggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgcctgg caggagatgt aatcggagat tattcctttg acagagagat
    13081 ccggattggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcacaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agcttgggaa tgtttccggt gtgactttgc tggaatgtga gacagatgac gcctgggcca
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggaggt acctttgacg ggctttaccg gaactgggaa aaggatgaca
    13681 gggtggctgc ctttatctgc aggactctcg gttgtccatg tctggatgcc agaccttttg
    13741 tgctggaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtctct ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacacgg gaagatgtgg atggttttgt gtttgaagag ggagaagacg
    14161 aacgggaaac cggagaacgg atggccgcca gttacgtgaa tttttatatt tccaatggag
    14221 gaattattct tcctcagttt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc agagagaagg atttatccca ttgatgccag agccatcatt gttggcggtg
    14341 gaaatattca ctgtatcacc cagcagattc ccgggaagaa tatctgaccc tgatgcagaa
    14401 aactttgaga gtcatgtgtt tgagggttat acctgaaagt tatgaaaaaa cttacttatg
    14461 taaacaggag caggaggaac agacaggatg agaaatgtaa cagtggcagc agttcagatg
    14521 aaatgcagta aaagtgtgga gaaaaatatt gcccatgcag aggaactggt gcgtcaggca
    14581 gcagcaaagg gagctgagat tgttcttctt ccagagcttt ttgaacggcc ctatttctgt
    14641 caggagcgca gatacgagta ttatgaatat gcgcagactg cagaggaaaa ccctgcagtg
    14701 cgtcatttca gcagggtagc ggcagagctg gggattgtga tcccggtcag tttttatgaa
    14761 aaagaggtca ataataccta taacagcgtt gcggttctgg atgcagatgg gaagaatctc
    14821 ggcgtttacc ggaaaacaca tattccggat gaccattatt atcaggaaaa attctatttc
    14881 acaccgggag ataccggctt taaggttttt gataccagat ttggaaccat tggagttgga
    14941 atctgctggg atcagtggtt cccggaaacg gcaagatgta tggcactgca gggagcagag
    15001 cttctctttt atcccactgc catcggcagt gaacccatcc tggaatgtga cagcatggaa
    15061 cactggagaa gatgtatgca gggacacgct gcctccaacc tgatccctgt gatcgctgcc
    15121 aacagaatcg gtgaggaaac agtagagcca tgtccggaaa acggaatgca gaaatctgct
    15181 cttaattttt acggctcttc ttttatcaca gacaacacag gtgctctctg tgcagaactg
    15241 cccggagggg aagagggggt gcttgtaagc acttttgacc tggatgcatt aaaggcagac
    15301 agactgaact ggggactttt cagagaccgc agaccggaga tgtatgcaaa aattgtcggg
    15361 aaatgacata caagccaaaa ttccattgcc gcaggcaatc tggaatgaat tttggctcag
    15421 ttactgagaa cggagtgaac agtaactgag tttataagaa tttcataaaa agtttatgat
    15481 tatattagtt gctacctgcg gtatatatgg taaaataaga gtacgaacgt tactgataac
    15541 ggagcgagca gtagagtttt gacatgtatt tctggcaaaa tggagtgtag aagatgaaca
    15601 gaaaagaatt tttggaaatc ctgagaagcc agcttgccgg tcagatgcag gagggcaaag
    15661 cagcagcaca tatcagatat tatgaagatt atatacaatc tcaggtacgt ggcggacgtt
    15721 cagagcagga agtactacag gaactgggag acccgcatct gatagcaaaa actctgatcg
    15781 atacagatga tggaagtaca caggaagatt acggagagta ttcttcttac ggaagtagtt
    15841 atggcaatga gacagagctt cctcatcagc aggagaaaag atggaaaaaa gtaatcgatc
    15901 tttctacctg gcatggcagg gctgttgtta ttgcagcggc ggctgttata attgttttac
    15961 tgatactgat aatcggagtt gcgattccgt tttttattat tcttgcaatt attctttatt
    16021 ttctttcatg gctgaagaaa agaaatgatc aatgaaaatc tgtgcaggat ttcagaaaag
    16081 aaaccctgcg cagaatctta aaaatcttaa gtgtaaacgt tcttgtttca cgatattaat
    16141 tccccttgaa tatttataat catacaatct caacttattt ctattcttta atcctgccag
    16201 gtgcagggaa aaatcccaca ttcattttta tattttttgt tcggaaagga gacggaaaat
    16261 gaaacacaat ttcaaactga aagaacgcct tggagctttg ctgcttgcaa tgctttttgt
    16321 tctgcaggca attctggggc ttgtgcctgt ctgcgaaact caggcggcac cgttaactgt
    16381 agaaacatgg gacagtgaca aggtggtaga ttatggttat cgctttaaca tgaagtttca
    16441 gcccggaatt accacatatg aatcttttgg gtgtgataat ctggacaggg aagctttttc
    16501 agacaatgga aaaagtgaac gtgacacaga gtgcgttcgt gtaggagcgg actataaagc
    16561 cggaagcgca gggatgcgtt ataacaatgt aggaaaagat ggaaatggaa atattgttga
    16621 tgtcagactc attcttgtgg gagtagagaa tgcagaaccc cgttatgatc tgcgcactgc
    16681 agaatcgatt gttcagaata aaggcggagc tacgtttgca tggaaagata atgaagctta
    16741 tccaatggtt ggcttttcca aaaacagtat cggtgtattt atttattctg taggatacgc
    16801 aaaggttaag tttcagtttc tgaagcatgg aacagaagaa acactgccga tcagtggcca
    16861 tggaaccata cgtgatattg atgcgggaca gggagtccgt attccgtcag acagcagtct
    16921 ggataatgca tatgttctga aaaacaatga ttatctgacg gtagatggaa attctgtaag
    16981 ctcacccctt ggttccgttg agccggatga tccgagagga tggctgaatc ttttttataa
    17041 tacagataat tttacggtag aattctgtca tcagttcaga ctggataaat gggataaaag
    17101 tcgtgaagat gccattgcaa aagccggttc tcaggaaaga tgggcagaga ttacaagaaa
    17161 taaatatctg gatccatcag gcaacagtta ttgtccgaac tttaaaggac agaaatactg
    17221 caaagcatat gcatattttg attttacatc ctattgtttc ggtgatgttg agatgaaaaa
    17281 agcgcctgag aaacgtgtgg gagaggcaaa ctgtacatgg gaacaggcag ctgccgcatc
    17341 aaaagaaaaa ccttttggca ttcgtcaggg acaggaattt cagtatatga tccgggcgga
    17401 ggtgacaccc aatagactga gatcctttgt ggtacaggat atacttgagg attgtcttac
    17461 tatagaggat gcatcaaaaa tcagtattgt gaatgatgca gggcagacag tgacagactg
    17521 gtttgatgtt gctgttgaag gacagaaagt gacctgcagg gccaaagcag agagccttca
    17581 ggatgaagca tttacagata atcagactta cacatttact ttaaaagtac gccagagacc
    17641 ggaatcagaa attaacattt caaaatacct tgcagaggat gggtacagta ttcttgtacc
    17701 aaaccatgta tccatgagtt atgaacgtac aaacggaagc ggagatacaa tggatacgga
    17761 aacagtgtgg gtaaagggtg tgattccacc ggaactggaa gtaaagaaaa atacttctca
    17821 gtatgaatgg aaaacgggag atatcataga ttatgaggtt ctggtttctc agacaaaaca
    17881 ggatgtaaaa gcagtaaatg ttgttattac agatgagctt ccatcatgtc tgcagcttct
    17941 ggaagggcag tatgctgtag agacaagtca gggaggtgag aactgtacgc ttaccggaca
    18001 gggagaaaat ggatggaaag cagagtgtcc gtccctgaag tatggggaga cgatcacaat
    18061 ccgttttaaa tgtcaggcat ctgcggattc caatggacag gaatgggaaa atattgtgac
    18121 agcaacagcg gataatctga tcaatcctga gacaggagaa caggaatcca gaaaggatat
    18181 ggcagaagta tggccgaaca gtccacagct tgaaattgat aaaacagcag acaaatatga
    18241 atggcaggca ggagagcagg tagcttaccg gatcgtagtg aataatgtaa cggcaggaac
    18301 aatcgcaaaa gatgtaacta ttactgatat tggtctgccg cagggactgg ttctggcagg
    18361 tggtgcacag agcatggaag tactgggagt tcagcaacag gtaaactatc ccgtaccgga
    18421 taagaaaaca ggacaggcat atgaagcgag atctgtggat tctcagttga atgcagatga
    18481 gaacggattt tccttttatt gttcttatgt accatacagt cagcctgtaa cgattatttt
    18541 ccattgtatc gcacaggaag aggcaaatgg acacgaaagc gtaaatgcag caactgtaaa
    18601 agctgctaat acagatgaga gatctgatga tgcagaagta tatgtaaatt caggagaatt
    18661 ctggattgag aaatctgcag atcattatga atggcaggtc ggagaacagg tacagtacaa
    18721 tgtggtggtg gagaataaaa aagcaggtac agtggcccgg aacgtaactg tctgggatac
    18781 cggtatgccg gcaggacttg cgctttcatc ggcagaggat gtatcggtaa gcggaattcc
    18841 acagaatatt acgcagctga cagcagggac caaagatgtt ttgaaccagc tcaatccgga
    18901 attttataat gagacatcag agaaaccggt gaattatgaa tttcttcagg agggaagcgg
    18961 atggagactg aacatttcag atcttccggc aaatactccg gttatgattt ctttcctttg
    19021 cacagttgcg gaagcggcaa atggaatgga aagcattaat gttgccaatg tgcaggcgca
    19081 gaatgcccct gtttcacagg atgacgcaga agtgtatgta aatacagcag ttctttctat
    19141 tgagaaaagt tttcagaatc catatctggc agccggggac ggacgtgcgg aaaatgaatt
    19201 tcgggtagga gaacaggtga attatcaggt tacggttaat aatcttcaga agggatctat
    19261 cgcaagaaat cttgtgatca gtgatctttc ccttcctgaa gggctggctc tggacggagc
    19321 tgaagatgct gttactgtaa gcggtgttcc ggctgttatt cagaatccgg tggcaggaac
    19381 tgatgatgca ggaaatcagc tgaatccgga aaattataaa gaaacagtgg aaaaaccggt
    19441 cagctgtcag gttacacgtc agggaaccgg atggatcgtg acgatttcag atcttccgta
    19501 tcagacacct gtgactgtta atttccgctg tactgcgcag gaaagcgtaa atgggatgga
    19561 gattgtaaat acagcacagg cgtatgcaga taatgcacag aaagtaaagg actcctcaaa
    19621 aatctgggtg aactcgcctg ttcttaacgt agagaagacg acggacaaac cattttacaa
    19681 atatggtgat attattacat accgcattgt cctgacacag gagcagaccg gatgtgtggc
    19741 gcgtaatgtt actctgcagg atgtgatcga tactcaggga gtacgtcttc tgaaggattc
    19801 ggtgattctg atggatgaga aaggaaatgt ggcagatgct gatgtacaga tcaatgatga
    19861 taatactttc ctgatgtcaa caggcaggac actggtcagg gacagcagat atagtatctg
    19921 cgataatgat aaaggcggtc tttttgagca ggtaatgtat aatcctctgg actgtcagga
    19981 acagaaaagt atgatcgtgg aatatcaggc agcagtgatt gatgcagccc tggcaggaca
    20041 gaaagtgcac aatactgcag ttgcagacag cagtgaaaag atacctgcaa ccggggaaac
    20101 agagacagag gtacacagtc cgattctgga aattgtgaag gaatcagata agaaagagta
    20161 tgcgtccggt gagaaaggat actataagct gacagtaaga caactgcgtg aggatgtcac
    20221 agatcagaat attgttatcg aagataaact ggaaacccaa ggggcttcta ttgtaaaaga
    20281 cagcattttt gtgaagaaaa acggcataga gctgaaagat gccaaaatag aggcagatga
    20341 tacaggattt gtaattcaga caggagcatc gttgtcagat atggataaaa ttgaagtctg
    20401 ctatgaagtg gtatttaaaa cagaaagcac agagcctgaa aaaattgtaa acacagcgaa
    20461 agcaagagga gatatttcac cggaaattgc ggcgcagcag gaggtatatg tgaaaacaaa
    20521 agcagaaccc actgccacac caacaccgtc tgcaacaccg aaaccaacag aaacaccaaa
    20581 gccgacagag acaccaaaac ctacagaagt accgaaaccg acggagcagc caaaagccac
    20641 accaacacca tctgtaccgg gaacctgccc gaaaatgact cctgtaccga cgaaagcacc
    20701 gttggcatct tacaatggtg gaaataatgg aggcacaact tccggaaacg gaggcagcag
    20761 ttacggaaat tcgggtggat acggaagcta tcagggtggt tccatggcag gaagttctaa
    20821 aacaggagat gtcagaccgt ttaaaatgat ggctgttctt ggacttatcg gaatgggact
    20881 gctgacagga ggtgtggtga tctacagaag aactgtttcc gggaaaagaa atataaagga
    20941 tatgccgcgg aaatgaaaaa actcagaaca tttgcagtaa gtatgatcat agcagcaatt
    21001 gggcttctta tatattgtgc cggcttctat ataaaaagtt atgaacagaa tcttgcagca
    21061 aggcaggaat atgcagagct ttcccaaatg gcaggggtga agaacagaga aggtgccgga
    21121 ttattggcag atggcaaaaa aactgatgaa gacagtagta caaaaaacag tgaaaaaaaa
    21181 cgcaggaaaa aacagagaag atcttctgaa tcaaaaaaca aaaactgtac agatgaaatc
    21241 agggaatcct tcgggatttc ctgggaaaat ttaagaaaga tcaactctca gacagttgcc
    21301 tggattactg tcccgggagc cgatatttct tatcctgtag ttcaggcggc agatgatgaa
    21361 tattacctga aacataattt cagaggagag gaagatctgt ttggatgtat ttttctggaa
    21421 catgacataa aaaagaattt tacagattcc cacagtattc tttacgggca taatatagaa
    21481 ggtaatatga tgtttgcaaa tctgaaccgt tatgaacagc ctgaatttct aaaaaaatgt
    21541 cctgaaattg agatcacaac accaaaaaga aagtttctgt acaaaatttt ttctgtggaa
    21601 caggcatctt cccaaagccc ggcatttgaa tatggataca agttatccag tcctgcatac
    21661 aggagacaat tatctatatt gaaaaataat tccatgtatg acacaggagt agagcctgat
    21721 gaaagggaga gaatggtgac tctgatcacc tgtaattcac gtctggataa agaaatacgt
    21781 atggcggtac atgggatttg ccatgaatgt tatggtatag aaaaagctga gccgaagtga
    21841 tgttgaaatc aatcggatat tggtaacttt cgtaaaggat gaactgttac tgttcacaca
    21901 tcactatccc tcgaggtgtt ttggaaaaaa ctaatgaaaa atctctcgat attttgtata
    21961 atttatgcat aaaaaacaac ttgttcgtac gtgcgtacaa gttgtatcct aaatacagga
    22021 gggaagaaga catgacagat aatggaaagc cgaaatattt ctcactgatg gaacagctca
    22081 gaagtgatat tatgtcagga gctatccgac cgggagagaa gcttccttca gaaaacgagc
    22141 tttcacagaa atattccctg agtagacata cagttcgtaa agcactggga atcctggagc
    22201 aggacggata tgtagaggca tttcacggaa gaggtactta ttgctctgag aatatgcgcc
    22261 atataaagaa ttcaaagaat attgcggtag tgaccacata tatttctgat tatatttttc
    22321 cgagactgat acagggaatg gataatgtcc tttcagaaag cggttacagt attatcctga
    22381 aaaacacagc aaacagcaga cagaaagagg ccagatgtct ggaggaactt ctgaagaaag
    22441 atattgatgg actgatcatt gaaccaagca aaagtgagat gatctgtaaa cacagaaatc
    22501 tttatcagaa tctggataaa tttgaaattc cgtatgtgtt tattcaggga atctattcag
    22561 aaatgaggga taaacctcat attcttatgg atgatgcaca gggaggctat cttgtaacaa
    22621 aatatctgct ggaactggga cataaaaaga tcaagggttt ctttaaggca gacgatatgc
    22681 agggactgga gcgccacaag ggatatgtga aggccttaca ggagtcaggg attgcctatg
    22741 atcctgatga tgttgtctgg tttcatacag aggacaggaa agtaaaacct gcactgatgg
    22801 caaaagaaat ggtacagagc ggacagcttc cggatggaat cgtctgttac aatgatcaga
    22861 ttgctgttca ggttatggaa gaactggaga aaatgggagt caggataccg gatgatattt
    22921 ccattaccgg ttatgacaat tcactgtatg ctcagcgagg aagcggaatc acaacgatag
    22981 ctcatccgca ggaaaagttg ggagaaatgg cagcagagct tatacttgag aagatcaacg
    23041 gagttcctga agaagaaagt aaggttgaaa gactgattta tccggaactg atcatacggg
    23101 gatcatgcag aaaaatattg taaacaaatg aaataaataa aaaataaaaa taaatccggg
    23161 aggaatttta tcatgaaaac aggaagaaac tataagttct ggttttgtac aggttcacag
    23221 gatctttacg gagatgagtg cttaagaaa
//
