LOCUS       gnlProkkaEIKHKFCI_443  10302 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EIKHKFCI_443.
ACCESSION   gnlProkkaEIKHKFCI_443
VERSION     gnlProkkaEIKHKFCI_443
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:18:25
            Original ID  :: gnl|Prokka|EIKHKFCI_443
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10302
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10302
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2:302]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..302
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10302
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10302
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..302
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg443_1"
                     /sec_met_domain="PqqD_RRE (E-value: 1.9e-10, bitscore:
                     31.6, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.3e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGHITTEWEGECAVLAYPRFKYEWMRRFLLPKGMSPDIHVRLEEH
                     GTAVWNLIDGHRTVREIISLLARHFGEEENYIPRVTAYVMQLRKDGFIQLTIRN"
     CDS             complement(310..1278)
                     /locus_tag="ctg443_2"
                     /transl_table=11
                     /translation="MRGKDYGVTYMLPKTEIEIVLQATKHTYTPGEFCRYADRYLRLNN
                     VSAEPEEFWTLDKIETRIAGVPDKDNVYFVKMKDKTVAPLMELTEDGIVRSINIPFSGK
                     PAAKTPEAKATESSIDPRSFLTEEILMSNSSAKMAELVAKEIYSIRESKNALLRGEADN
                     MPKDGAQLKLMLDNLNQQETAMTEMFSGKIKKEPKTFTIRLTPKEMKDEVAFRFSRKLG
                     VVANNDLAGEPYYISVTDLKSPDVSATEEGKKKVDGVAYNLPGKAQVTLVYNNKKLFDD
                     QLPITQFGTVEYLAPVLFNKNSTIKVLFDTATGGLIKVDRE"
     CDS             complement(1430..2557)
                     /locus_tag="ctg443_3"
                     /transl_table=11
                     /translation="MKTLLFCMLGLGLTACGSSPKGTNGDQDELAMLIGTYTNGSSKGI
                     YTFRFNQETGTAVPLSSAALPNPSYLVPSGDGEFVYAVSEMNDSTAALSSLSLDRETGE
                     LRLLNTVPTFGADPCYVATNGREVLTANYSGGTMSVFPLQKDGTLAPADTLFQGSATGP
                     DAIRQATPHIHCTVFSPDGKYIFATDFSADRILRFVMHPDDPIPHASLEAVDIEADSGP
                     RHLTFSPNGKFAYLITELSGKVIAFSYDDGCLEQIQTITADTVAARGSADIHLSPDGKY
                     LYASNRLKEDGIAIFAVNPENGTLAKVGYQPTGIHPRNFNITPNGKYLLAACRDSNVIQ
                     VYKRNEVTGLLEDTHQDIVVDMPVCVQFVSSVNNL"
     CDS             complement(2659..5631)
                     /locus_tag="ctg443_4"
                     /transl_table=11
                     /translation="MEDIFSKRKTLRTIKADTSDYFIPLFHTLAVFLSTKETIITKRFL
                     EHIMKNLIALTLLLGGSTLLCAQKPAKTPATYKPVKSEMYRKGWIDFNKNGVKDVYEDP
                     SAPLEARIENLLQQMTLDEKTCQMVTLYGYKRVLKDDLPTPEWKELLWKDGIGAIDEHL
                     NGFQQWGLPPSDNAYVWPASRHAWALNEVQRFFVEDTRLGIPVDFTNEGIRGVESYRAT
                     NFPTQLGLGHTWNRELIRQVGLITGREARMLGYTNVYAPILDVGRDQRWGRYEEVYGES
                     PYLVAELGIEMVRGLQHNHQVAATGKHFAAYSNNKGAREGMARVDPQMSPREVENIHIY
                     PFKRVIREAGMLGVMSSYNDYDGIPVQGSYYWLTTRLRGEMGFRGYVVSDSDAVEYLYT
                     KHGTAKDMKEAVRQSVEAGLNVRCTFRSPDSFVLPLRELVKEGGLSEEVINDRVRDILR
                     VKFLIGLFDAPYQTDLAGADREVEKEENEAIALQASRESIVLLKNAGELLPLDINSTKK
                     IAVCGPNANEEGYALTHYGPLAVEVTTVLEGIQEKTKGKAEVLYTKGCDLVDAHWPESE
                     IIDYPLTDDEQAEIDKAVENARQADVAVVVLGGGQRTCGENKSRTSLDLPGRQLQLLQA
                     IQATGKPVVLILINGRPLSINWADKFVPAILEAWYPGSKGGTALADILFGDYNPGGKLT
                     VTFPKTVGQIPFNFPCKPSSQIDGGKNPGPTGNMSRINGALYPFGYGLSYTTFEYSDLD
                     ITPRVITPNESATVRLKVTNTGKRAGDEVVQLYIRDVLSSITTYEKNLAGFQRIHLEPG
                     EAQELSFTIDRKHLELLDADMKWVVEPGDFVLMAGASSEDIRLNGTLTVEDYQTRAKAI
                     EAQKPAKRVSASTNPEDAENVLDEKINTAWQGNKGDYITFALKNGAKVDKVAIAFTRDN
                     NLPATFEIQLSGGGGQFLTVYSGTVSEYGKLISYPFKGTTASDLRIVLNDDRVSIAEVK
                     F"
     CDS             6215..6325
                     /locus_tag="ctg443_5"
                     /transl_table=11
                     /translation="MKNKVAFIPFSPSLLSNELRNLLNFRPLQSHGVDWI"
     CDS             complement(7090..7197)
                     /locus_tag="ctg443_6"
                     /transl_table=11
                     /translation="MPYPLKFRKSYEEKLKLFPILLCHFIKRFGTRAFE"
     CDS             complement(7182..7310)
                     /locus_tag="ctg443_7"
                     /transl_table=11
                     /translation="MWTWGESNSRPNEETICFLHAYLCLKFSNISKTKATNLCLIL"
     CDS             complement(7415..9304)
                     /locus_tag="ctg443_8"
                     /transl_table=11
                     /translation="MKKNERISSINSVLQDYFTKHPQSEMTLAKEFMHLFIKNGIFNKD
                     YKEGLPIRKILRALDDENSLDKIPYVHAERKPKITNWYFRPLFLSFVIFMGTLSSCSFK
                     SNTDFPEVTHVAFQKEKHGKWGMVGVDGNILFENKFDKRPSYAVNGVFRVWDYDTNQYL
                     YYSATPTPKLIGTPKGYKQGGVCSEGIIPVVSTDERIHYLTETGETAFYLLPYQGKEFL
                     CVSPFFTEQRAWFRLENRKCGYIDPQGNVVIEPIYDNAFPFHEGKAIVYNKEVDKWLVI
                     DPNGKELFEASSNGYQQYSYTFFENGYCLIENFLLNEKGEKAQRFPSNIYSISPFIDNV
                     ALFQDSKTGLWGQLNIQGESIVEPKYSRALGIVGDWIYVADTIANLKDDWDNQYMNVYA
                     INSKGEIKNKIENVSCFYPLSQYIIMAENEKYYFANKKGNPVDNNSYYKISVPPFTNSP
                     SYSSFWSSLIAPHSLSDYDAWGVVTNYIDEKKTLASIFDKLTSDGIDSLKMGQPISRIM
                     DLYNIKQMPASGMVDLHNRDWGINQVFATYSVGILYECKCVIVIKVEINANASPIGDNP
                     QKLFDAIPQYLTETLGLKREDENLYRSKDACYDIVYCKGENSFFLMSKAMTEE"
     CDS             complement(9323..9937)
                     /locus_tag="ctg443_9"
                     /transl_table=11
                     /translation="MKKIITSIFILMFYLGCSPSQKDVLFANASDEQIIEWGKQYVVHS
                     IEDSLKEGESYKIMEWILAEKKTSIPVEVWQMDNTYKKDSIPGCTKLLDTRGIFDELAF
                     IGNGDSAFVAFAVAYTINEKNGNCSFLEKTFTLDKNGKVSNCSDYLSPSQKMKQTEEKF
                     HKALEQLGPFLIQAVKEGAAMAGKDTSGITNVTINGKTYSE"
ORIGIN
        1 gctgtggaca tataacaacc gaatgggaag gtgagtgcgc cgtactcgcc tacccacggt
       61 ttaaatacga atggatgcgt cgttttttat tgccgaaggg gatgtctcct gacatccatg
      121 tgaggctgga agaacacggt acagctgtct ggaatctgat agatggacat cgtaccgtgc
      181 gcgaaatcat ctctctactt gccaggcact ttggggagga agagaattat attccccggg
      241 tcaccgccta cgtaatgcag ttgcgtaagg atggatttat ccagttgaca atccggaatt
      301 agaattcctt tattccctat ccacttttat caatcctccc gttgccgtat caaacagcac
      361 tttgatggta gaattcttgt tgaacagtac cggtgcgagg tattctacgg tgccgaattg
      421 ggtaatggga agttggtcgt caaacaattt cttattgtta tacaccaatg tcacttgtgc
      481 cttgcccgga aggttatagg ctacaccgtc cactttcttt ttgccttcct cggtggcaga
      541 tacatcggga cttttgaggt cggtgacgct gatataatac ggttcaccgg caaggtcatt
      601 attggccacc actcccagct ttcgggaaaa acggaaagcc acttcatctt tcatctcttt
      661 aggcgtcagc cggatggtga atgtcttggg ttctttcttt attttgcccg agaacatttc
      721 cgtcatagcc gtttcctgct ggttcagatt gtcaagcatc agcttgagtt gggcgccgtc
      781 cttgggcata ttgtctgctt cgccgcgcag gagggcattc ttgctttcgc ggatgctgta
      841 tatttcctta gccaccagct cggccatctt ggcactggag ttggacatca gtatttcttc
      901 cgtcagaaaa ctgcgtgggt caatgctgct ttcggtggct ttggcttcgg gcgtcttggc
      961 agcaggctta ccgctgaacg gaatgttgat ggagcggaca attccgtctt cggtaagctc
     1021 cataaggggt gctacggtct tgtctttcat cttcacgaaa tagacgttgt ccttatccgg
     1081 tacaccggct atgcgggttt ctatcttatc cagtgtccag aactcctcgg gttcggcaga
     1141 cacgttgttg agacgcagat agcggtcggc atatctgcaa aattctccgg gagtgtaggt
     1201 atgcttggtg gcttgcaata cgatttctat ttctgttttg ggtaacatat aggtcactcc
     1261 gtagtctttg ccacgcatca caccggtggt tacgtctgtt tgcgccaggg cagtggtaga
     1321 caagaacaga gctgagaaca tcaatatatt cttcttcata atgtacattc gtttagactg
     1381 atttagctaa gggacaaagt taatgaagtt atctttgcta aatattgctt tataaattat
     1441 taacagagct gacgaactgt acgcaaaccg gcatgtcgac tacaatgtcc tgatgagtat
     1501 cttccaagag tccggtaact tcgtttcgtt tgtatacctg aatgacattg ctgtcgcggc
     1561 aggcggcaag caagtattta ccgttgggcg tgatgttgaa gttgcgggga tggatgccgg
     1621 tgggctgata acctaccttt gccaaggtcc cattttcggg attcacggca aagatggcga
     1681 tgccgtcttc tttcagacgg ttgctggcgt agaggtattt cccatccgga ctgaggtgga
     1741 tgtctgcact tccacgggcg gctacggtgt cggctgtgat agtctgtatc tgttccaggc
     1801 agccgtcgtc gtaactgaag gcaatgacct taccggacag ttcggtgatg agataggcaa
     1861 acttcccgtt agggctgaat gtcagatggc gcgggccgga atccgcttca atgtcaacgg
     1921 cttccagaga agcatgagga atagggtcgt cggggtgcat cacaaagcgc aggatacggt
     1981 cggcactgaa gtcggtggcg aagatatact ttccgtccgg tgaaaagacc gtgcaatgga
     2041 tgtggggagt ggcttgccgt atggcgtcgg gaccggtggc agagccttga aagagcgtgt
     2101 ctgcaggagc caaagtgccg tctttctgta aaggaaagac ggacatggtt ccaccgctgt
     2161 agttggcagt caacacttcc cggccattgg tggccacgta gcaggggtcg gcgccgaagg
     2221 tgggaacggt gttcagcagg cgcagttctc ccgtttcccg gtctaaggaa agggagctga
     2281 gggctgctgt gctgtcgttc atttcactga cggcatagac aaattcgcca tctcccgagg
     2341 ggacgaggta ggagggattg ggcaatgccg ctgaactgag cggaacggct gttcccgtct
     2401 cctgattaaa gcggaaggta tagataccct tgcttgagcc attcgtgtaa gtacctatta
     2461 gcatggcgag ttcgtcctgg tcaccgttag tgccctttgg agaagagcca catgctgtca
     2521 aacctaatcc gagcatacag aaaagaagtg ttttcattaa tttaatgtgt taatgtgcca
     2581 atatgctaat gtgctaattg gctgcgctgt atatgctgca tggtcattgg tacattagca
     2641 tattggcaca ttagcacatt aaaatttaac ttcggcaata ctgacgcggt catcgttcag
     2701 cacgatgcgg aggtcgctgg cggtagtgcc tttgaacgga taggaaatca gtttgccgta
     2761 ttcgctgacg gtgcccgaat atacggtgag gaactgtccg ccaccgcccg agagctggat
     2821 ttcgaaggtt gccggcaggt tgttgtcacg tgtaaaggca atggcaactt tatctacctt
     2881 ggctccgttc ttcaaggcaa aggtaatata atctccctta tttccttgcc atgcggtatt
     2941 gattttttcg tcgagcacgt tttcggcatc ctctgggttg gtgctggcac tcacacgctt
     3001 tgctggtttt tgggcttcaa tggctttggc acgggtctgg tagtcttcta cggtcagcgt
     3061 tccgttcagg cggatgtctt cggaagaggc gccggccatg agcacgaagt cgccgggttc
     3121 caccacccat ttcatgtcgg cgtccagaag ctccaggtgc ttgcggtcga tggtgaagga
     3181 cagctcctgg gcttcgcccg gttcgaggtg gatgcgctgg aagcctgcaa gattcttttc
     3241 gtaggtggtg atgctgctca gtacgtcgcg gatatagagc tgcactactt catctccggc
     3301 acgtttgccg gtgttggtca ccttcaggcg gacggtggca gactcgttcg gggtgatgac
     3361 tcggggggtg atgtcgaggt cggagtactc gaaggtggtg tagctcaagc cgtaaccgaa
     3421 ggggtagagt gctccgttga tgcgtgacat gttgcccgta ggtcccggat tcttaccgcc
     3481 gtctatctgt gaagaaggct tgcaggggaa gttgaagggg atttgcccta cggtcttggg
     3541 gaaggtcact gtcagctttc caccagggtt atagtcgccg aagaggatgt cggccagggc
     3601 cgttccgcct ttggagccgg gataccaggc ttcgaggatg gcggggacga acttgtctgc
     3661 ccagttgatg gagagcgggc gtccgttgat gagtatcagt acgacgggct tgcccgtggc
     3721 ttgtatggct tgaagcagtt gcaactgccg gccgggcagg tcgaggctgg tgcgcgattt
     3781 gttttcgccg caggtgcgtt gtccgccgcc caatactacg acggcaacat cagcttggcg
     3841 ggcattttct acggctttgt ctatctcggc ttgctcgtcg tcggtcagag gatagtctat
     3901 gatttcactt tcgggccagt gggcatccac taggtcgcag cctttggtgt agagcacctc
     3961 tgccttgcct tttgtctttt cttgaatgcc ttccagtaca gtggtcacct ctacggcaag
     4021 ggggccgtaa tgggtcagcg cgtagccttc ttcgttggca ttgggaccac agacggcaat
     4081 cttcttggtg gagttgatgt ctaagggcaa cagctcaccg gcattcttca gcagaacgat
     4141 ggactcgcgg gatgcctgca aggcgatggc ttcgttctct tctttttcca cttcacggtc
     4201 ggcaccggca aggtctgtct ggtagggggc atcgaacaga ccaatgagga actttacccg
     4261 gaggatgtcg cgcacacggt cgttaatgac ttcttcgctc agcccgcctt ccttcaccag
     4321 ttcgcggagg ggaaggacga aggagtcggg cgagcggaag gtacagcgta cgttcagccc
     4381 ggcttccacg ctttggcgga cggcttcttt catgtctttg gcggtgccgt gcttggtgta
     4441 gaggtattct acggcgtcac tgtcggatac gacgtagcca cggaatccca tttcgccacg
     4501 caggcgggtg gtgagccagt agtagctgcc ctgtacgggg atgccgtcgt aatcgttgta
     4561 cgaactcatt acgcccagca tgccagcttc ccggatgacg cgtttgaagg ggtagatgtg
     4621 tatgttttcc acttcgcgcg gcgacatttg cgggtccacg cgtgccatgc cttcgcgggc
     4681 gcctttgttg ttactgtaag cggcaaagtg cttgccggtg gcggccactt ggtggttgtg
     4741 ctgcaagccg cgcaccattt cgatgcccag ttcggctacg aggtagggag attcgccgta
     4801 aacttcttcg tagcgtcccc agcgctggtc gcgtcctacg tcgaggatgg gggcgtagac
     4861 gttggtgtag cccagcatgc gggcttcgcg tccggtgatg agtcctactt ggcgaatcag
     4921 ttcacggttc caggtatgtc ccagtcccag ttgggtgggg aagttggtgg cgcggtagct
     4981 ttccacgccg cgtatgcctt cgttggtaaa gtctacgggg atgccgagac gggtatcttc
     5041 cacaaagaac cgttgcacct cgttcagtgc ccaggcgtgg cgcgaggcgg gccagacgta
     5101 ggcattgtcc gagggaggca gcccccattg ctggaagccg ttcaggtgtt cgtcgatggc
     5161 gccgataccg tctttccaga gcagctcttt ccattcgggg gtggggaggt cgtctttcag
     5221 tacgcgtttg tagccgtaga gggtgaccat ttggcaggtc ttttcgtcca gcgtcatctg
     5281 ttgcagcagg ttttcgatgc gtgcttcgag cggggcggag gggtcttcgt acacgtcttt
     5341 cactccgttt ttgttgaagt ctatccaacc tttgcggtac atttcacttt tcaccggctt
     5401 gtaggttgcc ggtgttttgg caggcttttg tgcgcagagc agtgtgcttc ctccaagcag
     5461 cagggttagg gcaataaggt tcttcatgat atgttctaaa aatctcttgg ttattattgt
     5521 ttcttttgtt gacaaaaata cggctaatgt gtgaaataaa gggataaaat agtccgaagt
     5581 atcggctttt attgtccgaa gggtcttcct cttactaaaa atatcctcca agacgctacc
     5641 ggggaattca aatcattatt agacgaaaca tatcattcac ttttaaaaag aaagagagaa
     5701 cactataata acctgaaaag tagatgcaat cgcggtgtat acaagtatta cggctacatc
     5761 tgttaaacga gggtgtattt atataatagg aatctgttgg cggaattgtt gcttgtacgg
     5821 aagaactttc ttttcaacct tgggatgtct aaacccaacc ttggtttaga catcccaagg
     5881 ttgggtatgg aaaaaccaaa gtttgggata gattgcttcc ttaattcttt ccggtttttc
     5941 agttaacttc agagactttt tccgttaact tcccatctct tttgtgcaaa tatccattac
     6001 agaagataga tattccctct tgcagggggt aattccgtca acggatactg gctttggtag
     6061 ctgtttgaac attgatgaca atggggtgca catattctat gtatggaaga ttattgtttt
     6121 tatcacgaaa agtcagtatt agctaatatt tgtaaatata tggtgattgc taataaaaga
     6181 atatgtatct ttgggccaaa gaaagcggta gaggatgaaa aataaagtag catttatccc
     6241 tttttcaccc tccctactta gcaatgagtt acgcaatctt ttaaatttca gaccgttaca
     6301 aagtcatggg gttgactgga tttgacagcg ggcagaaatg gtaagtaagc atgcagtgcg
     6361 tcgttgattt gcactttaat ctcagtcctc aaaattttat ctggcgaaac tcgttacgct
     6421 ctcgctgctt aatcgaagta tagtagattg aagcttaatc ccggcaccag gtgctgggac
     6481 gtgacatcac tcggaagctg ttgctccgaa gcattccgat aaagtggtgc agtcaaatcg
     6541 gggatagttc gtgtcagcct cgtggcgcgg gtgaaaattt agaggataag gcaacggttg
     6601 atggctttgg ttctgccgct gcacgaaaat ttaggcaaag ataagcatgt agaaagctta
     6661 tgatttcctc gtttggacga gggttcgatt ccctccagct ccacaataga tgttgattat
     6721 taggtagtta tgaataatac accctaattt acacccggtt taatgtggca gatgtttatt
     6781 tatcattctt tatattgaat gatagtctat ttcttaaata aattaacagt atgatatttt
     6841 ctaatataca aagatactaa tctatggatt tgtttaagta ataaagaaac gttatctttg
     6901 caaaatcatt ttgggcttga ctggaattga cagcgagttg gaatggtatg taagcatgca
     6961 gtgcgtggtt gattggcact ataatcccag ttttcaaaaa tttatctggc aacgaaaatt
     7021 atgctctcgc tgcttaatcg aagtatagta gattagcttt atttccgcca aagtggtaga
     7081 aacgagatgt cactcaaaag ctcttgttcc gaagcgtttg ataaagtggc acagtaaaat
     7141 cgggaatagt ttgagttttt cctcgtaact cttacgaaac tttagaggat aaggcataag
     7201 ttggtggctt tggtcttgct tatgttcgaa aattttaggc aaagataagc atgtagaaag
     7261 catatggttt cctcgtttgg acgggagttc gattctcccc aggtccacaa tacttagata
     7321 attatttttt atgtataaaa gtattcccgt acagaatttg atgtcctgtg cgggaatatt
     7381 tttaagtgtt cgatgataca tgaatatttc ttaactattc ctctgtcatc gctttagaca
     7441 ttaaaaagaa cgaattttct cctttacaat aaacaatatc ataacaagca tctttagagc
     7501 gataaaggtt ttcatcttcc ctttttagtc ccaaagtttc tgtaagatat tgtggtatag
     7561 catcaaataa tttttgagga ttatcaccta tcggtgaagc attcgcatta atctctactt
     7621 taatcacaat tacacactta cattcataaa gaatgccgac ggaatatgtt gcaaaaactt
     7681 gatttatacc ccaatctctg ttatgcaagt caaccatccc acttgctggc atttgtttta
     7741 tattgtataa atccataatt cttgaaatag gttgacccat ttttaaacta tcaatgccat
     7801 cggatgttaa tttatcaaat attgacgcca atgttttctt ttcatctata taattggtta
     7861 caactcccca agcatcataa tcagacaagg agtgaggtgc tattaaagaa gaccaaaagg
     7921 atgagtaact gggggaattt gtaaatgggg gaactgaaat tttgtaataa gagttgttgt
     7981 ctactggatt ccctttcttg ttagcaaagt aatatttctc attttctgcc attatgatat
     8041 attgggataa tgggtaaaaa catgaaacgt tttctatttt atttttaatc tcacctttag
     8101 aatttattgc atatacattc atatattgat tatcccagtc atcttttaaa ttagcaattg
     8161 tatcagcaac atatatccaa tcacctacaa tacctaaagc tcgcgaatac ttaggctcta
     8221 caatgctttc tccttgtatg ttaagttgtc cccataatcc agttttactg tcttgaaata
     8281 aagcgacatt gtcaatgaaa ggtgaaatac tataaatatt agaggggaat ctctgtgctt
     8341 tttcgccttt ttcattgagt aagaagtttt ctattaaaca atatccgttt tcaaaaaaag
     8401 tgtatgaata ttgttggtat ccattggaac tggcttcaaa taattctttt ccattggggt
     8461 cgataactaa ccatttgtca acttctttgt tatatacaat agcttttcct tcatggaaag
     8521 ggaaagcgtt atcataaata ggttctatca caacattgcc ttgtggatct atatatccgc
     8581 atttacgatt ttctaatcga aaccaagcac gttgctccgt aaagaacgga gatacacata
     8641 agaattcctt cccctgatac ggaagcaaat aaaaagcagt ttctcccgtt tctgttaaat
     8701 agtgaatacg ttcatccgta gacacaactg ggattattcc ctcactacat acacctcctt
     8761 gcttataacc ttttggagtc cctattaatt taggagttgg agttgcggaa tagtaaagat
     8821 attgatttgt atcataatcc caaactctaa acactccatt tactgcataa gacggtcttt
     8881 tatcaaattt gttttcaaac aagatgtttc catcaactcc aaccatgccc catttcccat
     8941 gtttttcttt ttggaaagct acatgggtca cttcaggaaa atcggtattt gacttaaaag
     9001 aacaactcga aagcgtaccc ataaatatta caaacgataa aaacaaaggg cgaaaatacc
     9061 aattagtaat tttaggtttc ctttcggcat gaacgtaggg gattttgtct aatgaatttt
     9121 catcatccaa agctctcaga atttttcgaa tgggtaaacc ttccttataa tctttattga
     9181 aaatgccatt ctttataaaa agatgcataa actcttttgc aagagtcatt tcgctttgag
     9241 gatgtttcgt aaaataatct tgcaatacac tgttgatact tgaaatacgt tcatttttct
     9301 tcataatacg tcatattata agttattcgg aatatgtttt tccattaatc gtcacatttg
     9361 ttatgccact tgtatctttg cctgccatag cggcaccttc ctttaccgcc tgaatgagaa
     9421 aaggtcccag ttgttccaaa gctttgtgga atttttcttc tgtttgtttc atcttttgag
     9481 aagggctgag gtaatcgctg caatttgata ctttaccgtt tttatcgagg gtaaatgttt
     9541 tttctaagaa tgagcagttc ccattctttt catttattgt atatgcaaca gcgaaagcta
     9601 caaatgcgct atcaccgttt cctataaatg cgagttcatc aaaaatacct cgtgtatcta
     9661 atagcttggt gcatcctggt attgaatctt ttttatatgt attatccatt tgccatactt
     9721 caacgggaat acttgtcttt ttttctgcca aaatccattc cattattttg taactttctc
     9781 cttcctttaa actatcctca atggaatgga ctacgtactg tttaccccat tctatgattt
     9841 gttcatcgga agcgtttgca aatagtacat ccttctgtga tggtgaacaa ccaagataaa
     9901 acatcaaaat gaaaatagaa gtaataattt ttttcatgat gctatattat ttaagttaga
     9961 attaaatttt ttgattaatc cataaaagga gaagcgatta gacctattaa aattactata
    10021 caaagtagaa tgataatgat gattggaatc atcaggcaac cgccacatcc ttgtagaaac
    10081 tccgctttac cttttgcaaa ctctatttgg gctttctcat attcagaaag tctttcagca
    10141 ttttgctcct tcataacttc attgtttgtt cattggaaat atcaataacc attaatgact
    10201 tcattcatgt catctacaac ttttataaca ttcccgtcag aatccaatac aaaaagtttt
    10261 tcttccacta cgtaaccgcc ataactgttt ttagccctat at
//
