LOCUS       gnlProkkaEIKHKFCI_77   10684 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EIKHKFCI_77.
ACCESSION   gnlProkkaEIKHKFCI_77
VERSION     gnlProkkaEIKHKFCI_77
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:18:25
            Original ID  :: gnl|Prokka|EIKHKFCI_77
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2582
            Orig. end    :: 13266
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10684
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10267]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10267
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10684
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10684
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             717..1565
                     /locus_tag="ctg77_3"
                     /transl_table=11
                     /translation="MNISEFNINAEFIACNHITTNELNPLVEKPYHTKASIFALCTKGV
                     LKTIINHTQFRVEANTLLVIPPETFVQLLHTSDDAEIYVVIFSQQLIQSSGAGKVMMDK
                     FHIIGKHYIFPLSKTDFQLYAEFMTYLSHLYQRTESPSSLVSLQTLLTYLLQGISELCP
                     ERPRIKETPGSRHFNQYRIFIRLVHTDYVREHQVSYYALKMNMRPAALCRLVKKESGHT
                     AMEIINNTIIMDAKAQLCTANTPIKDIAVSLGFNNAAFFNKFFKRHTGIPPQKFRTSSK
                     Q"
     CDS             complement(1640..2416)
                     /NRPS_PKS="Domain: oMT (51-145). E-value: 6.2e-11. Score:
                     32.8. Matches aSDomain: nrpspksdomains_ctg77_4_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 78.7; E-value:
                     7.7e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg77_4"
                     /transl_table=11
                     /translation="MSNENKTIHDFELSLICDFFSNMERQGPGSPEATLKALSFVDGLT
                     DKSLIADIGCGTGGQTIVVAGHVPGRITGIDLFPGFIDIFNRNARQLGLQDRVKGIVGS
                     MDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGYIAVSESSWFTDERPAEIN
                     DFWMDAYSEMDTLPNQVAKLYKAGYLPVATFILPENCWTEHYFASKVAAQEIFRKKYAG
                     NKIAEEFSSLQMIEDELYGKYKEFYGYVFFIAKKVD"
     aSDomain        complement(1982..2263)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg77_4_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="6.20E-11"
                     /label="ctg77_4_oMT.1"
                     /locus_tag="ctg77_4"
                     /protein_end="145"
                     /protein_start="51"
                     /score="32.8"
                     /tool="antismash"
                     /translation="DIGCGTGGQTIVVAGHVPGRITGIDLFPGFIDIFNRNARQLGLQD
                     RVKGIVGSMDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGY"
     CDS             complement(2650..2982)
                     /locus_tag="ctg77_5"
                     /transl_table=11
                     /translation="MKQLIACCGLDCENCAARIATVNNDDELREKTAKEWSVLNNTPEI
                     TAETIHCMGCRADGVKFAYCSDYCAIRKCVYEKGFNTCGDCKELDTCQVVGAVLQHAPG
                     AKENLY"
     CDS             3815..4174
                     /locus_tag="ctg77_6"
                     /transl_table=11
                     /translation="MDICKNMESLIMKNCYGIDFRSWRKELRTREKTKQTPCKLPDRVS
                     RSLQGVLFKVYQISVLILLKKILFSFFSVCLPLFIRHIAAMLLRKTSSKTMQTVTKYLK
                     ELSGVRSDNSPNSYK"
     CDS             complement(4315..4491)
                     /locus_tag="ctg77_7"
                     /transl_table=11
                     /translation="MFVYPLFRPSHCPFPGYTTVTHVVCVYTIPLMGENHINIDVSILV
                     VIFREIFKVAKFE"
     CDS             4541..4756
                     /locus_tag="ctg77_8"
                     /transl_table=11
                     /translation="MKQNKPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             4770..8348
                     /locus_tag="ctg77_9"
                     /transl_table=11
                     /translation="MMKLRNLMQVACMATAALTAFSCSQEEFENSGRKGNITVNATFEG
                     AGTDTRTTVNDEYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSG
                     ETAVFSIYPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMA
                     AMIKLTVNKIPAEATTFKIIASNNIAGTCTVDLTAADPILAVTSDESKEITASFTASAD
                     IKSRNFYIPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVEAT
                     TPSALSTALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLAFN
                     TAPTTSTAAPLTLTDKTNTSIGAPAATATNSVSLAVPETNAEQEAPSVAITMPSTTVTL
                     AAVGNKATYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGDTTIYI
                     IKGTEASLPATIDSKFVVQSDVAVLKAAFANGEDFKLSADADITGQSVSVPAGKSVVLD
                     LNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDAS
                     MTMESGNISAVRKTPNSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIIN
                     ITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGST
                     GNWGDGTGGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFS
                     DPSALKYMKTNANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETN
                     SCQLLEGSNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINN
                     TTINAGSNANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTEPMKLNITGG
                     TFNGDLKVDASVGTENAKSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTELA
                     TGYILNAANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASAT
                     AKDDGYRMVIEARGHGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYG
                     TPNNDTDGRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDG
                     SVYTAAHKVNDGRKEYIVGPTSQENR"
     CDS             8595..9521
                     /locus_tag="ctg77_10"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETATKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVATVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             9548..9988
                     /locus_tag="ctg77_11"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVTVLARDLTERIVFHRIIRRNGDILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             10001..10267
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg77_12"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-13,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.8e-16, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             10276..10683
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg77_13"
                     /sec_met_domain="NTP_transf_5 (E-value: 5.9e-23, bitscore:
                     71.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRVLYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIAN"
ORIGIN
        1 aacgcggttc tataatcatc agattatgtt ccatgtcgaa agaccattga aatatctggg
       61 tgcggctcag cgcaatattc agcaaatgct tctgtgtccg ttcttccaac acattcctga
      121 aatagagtac aatcctcacc aattgtccat cttcatgaat tcccaccata gcaccttgta
      181 tcagaaaact gataccactc ttcaattcac gtataaagca attgatatct aagggaataa
      241 tccgcacatc cctctcccga agttgcagca aaaggtcttc taacacattc tttttatcac
      301 ataccacttc caataagtca gtgatacgcc gccctatcac atactcattc aaatggagtt
      361 cattcatcac ctgctgattc agacgccaga tacaatcttc caaatcaatc ataataatgc
      421 tgacgggcca tgagttgaac aactgctcgg agatggcatt tattatacgt acttcttgag
      481 gaacattcgg attcatcaga attgttttat catacaagga gcaaagttcg ggctaaaatg
      541 cttatgccac aaacaaaccc ttataaatca atattccgtt ttagcatgta tatattctat
      601 tattcacaac tttaccttat ttaacagaga caaattgagc gtaatattga ttttaactgt
      661 tatctctgtc atttatacat tattatcccc catttttgtg tcttaaaatc tccaacatga
      721 atatatccga attcaatata aatgccgagt tcattgcctg caatcatatc acaaccaatg
      781 aactgaatcc gctagtggaa aagccatacc acaccaaggc cagtatcttc gctctatgca
      841 ccaaaggagt tctgaaaacc atcataaacc atactcaatt cagggttgaa gctaacaccc
      901 tcctagttat tcctcccgag accttcgtac aattgctaca cacgtcagac gatgctgaaa
      961 tatatgtcgt catattttcc caacaactta tccagagttc aggggccggc aaggtcatga
     1021 tggataagtt tcacattata ggcaaacact atatttttcc tctatcgaaa acggacttcc
     1081 agctttatgc cgagttcatg acctatttgt cacacctcta ccaaagaaca gaaagcccct
     1141 caagtctagt ttcattgcaa actctactga cctatctgtt acaaggtata tccgaactct
     1201 gtccggaacg ccctagaata aaagagactc cgggcagcag gcatttcaac caataccgca
     1261 tttttatccg attggtacac acagactatg tccgggagca tcaagtgtcc tattatgcat
     1321 tgaaaatgaa tatgagaccg gcagctcttt gccgccttgt caaaaaggaa tcaggacata
     1381 cagccatgga aatcatcaac aatactatca tcatggatgc caaagcacaa ctttgtaccg
     1441 ccaacactcc gataaaggat atagccgtga gtctaggttt taataatgcg gccttcttca
     1501 acaaattctt taaacgtcat acgggaatac ctcctcagaa gttccgcaca tcctcaaaac
     1561 aataaaatcc actcaaaaca caaaatgcgg atattctgcc atgagaatac ccgcattcct
     1621 caataagaga agtctgccat caatctacct tcttagcaat aaaaaacaca taaccgtaga
     1681 attccttata tttgccgtat agttcatcct caatcatttg gagtgagctg aactcttcgg
     1741 caattttatt accggcatat ttcttacgga aaatctcctg agccgcaacc tttgaagcaa
     1801 agtaatgctc tgtccagcaa ttctccggca gaatgaatgt agcaacgggg agataacccg
     1861 ccttgtacaa cttggctacc tgattgggaa gtgtatccat ttcagaatag gcgtccatcc
     1921 agaagtcatt gatttccgca ggacgttcgt ccgtaaacca tgaactctcg gatacggcaa
     1981 tataccctcc cggtttcaga tatttacgcc actccttcaa gccacgttca aagccgatgt
     2041 tatagatagc accttcacac caaatcatat ccagctcctc ctcaccgaaa gggagggcat
     2101 ccattgaacc gacaattcct tttactctgt cctgcaggcc caactgcctt gcattacggt
     2161 tgaagatgtc aataaagccg gggaaaaggt caattccggt aatccgcccc ggcacatgcc
     2221 cggctactac tattgtctga ccacccgttc cacaacctat atcggcaata agggatttat
     2281 cagtaaggcc gtctacaaag ctcaatgcct tcaacgtcgc ttcgggactg ccagggcctt
     2341 gccgttccat attggagaaa aagtcacaga ttaaactaag ttcgaaatcg tggatggttt
     2401 tattttcgtt actcattttc ttactatatt ttgcatatac ggaaagtatc acaatacctt
     2461 cagcataata cgcggattaa actttaatta taacaataga gaaacactct cgaaagaagt
     2521 tatccgagag taaacgaaag ggacaatctg tgcaaggaac acagattgtt tacaaaacca
     2581 aatccgattt aaatgtcttt gtcatactgc aaagataagc aatattttat ttaatcaaag
     2641 aatttacggt taataaagat tttcctttgc accgggtgca tgctgaagaa cggcacctac
     2701 cacctggcaa gtatccagtt ccttacagtc accgcaagta ttgaaacctt tttcgtacac
     2761 acatttgcgg atagcacaat aatcgctgca ataggcaaac ttcaccccgt ctgcacggca
     2821 ccccatacaa tggatggttt ctgccgtaat ttccggcgta ttgttcagca cactccactc
     2881 tttggcggtt ttctctctca gctcatcgtc attattgaca gtggctatac gggcggcgca
     2941 attttcgcaa tccagtccgc aacatgcaat taattgtttc atcacttggt tataaccatt
     3001 tatgtgtttc tcatagcaag catttgtcta cctcctcttt atctgaattt aagaggaggc
     3061 agacagccat gctacaaata tacggttatt attgtgtgaa tgccaaatta attttccatc
     3121 actttgcttc cacacttcca cccacctcct gcatccccct gtccatcggc atttgccctg
     3181 cggtggaagc aacctgaaaa ggtggaagca aaatttgctt ccacctgcct gaaacgcttg
     3241 agttttgcag taagctgcta tcccctacca taatacagca tgcagattac atgaatcggc
     3301 aggttcggtt ttcctgcatt ttcgggcttg tccttactgt gaagtcaacg gatatggagt
     3361 tggactgtag gggcatagta ggagttatcg ggaatcaaag gccgactatg aataatgcac
     3421 tctaatgtct tttacaccgt tgtataatac gtttgcgcct tgtgcgcaat aggttcgggc
     3481 tacgtacttc atccgtaata gctctggagt tagtgacgcc taacggccat gaacaactct
     3541 gcttacggtc gtcaagcgat cgctttatgg tcgaaagcag ggttgttcat ggccgttagg
     3601 cgtcataaat tccctatgcc acagcagaca aacaaaggga gaagagcaaa ggaataccta
     3661 tgttttagat aaaaatccac aagctttcac tcgtgctctc cataggttat gagagcaggc
     3721 ttcgcgctct gtgcgataaa ttcccattta tcagcaggca tactcactta cgaaacttca
     3781 attacttata taaattgttt cagccaaagg cagtatggac atttgcaaaa atatggaaag
     3841 tcttattatg aaaaattgct atggcatcga cttccgttcg tggcgtaaag agctacgtac
     3901 acgtgagaaa accaagcaga caccctgcaa actgccggac agagtaagcc ggagtttgca
     3961 gggtgttctg tttaaagtat atcaaatctc tgttttaatt ttgcttaaaa agattttatt
     4021 cagcttcttt tcggtctgtc ttcctctctt tattcgccac atagccgcta tgctcctcag
     4081 aaaaacatcc tcaaagacaa tgcagacagt tactaaatat ttgaaggagt tatcgggagt
     4141 tagaagtgat aactctccta actcctataa atgaaagaga cgtgagcctt tcccaaaaaa
     4201 aaatagagaa acatagatac acttaaacaa aaaacaatta tctttgtcac aaattcgcta
     4261 tagcgtagtg ggtttattta catattagta agagcattat tgaaattatc ttctttattc
     4321 aaacttcgca actttgaaaa tttccctgaa gataacaaca aggatgctca cgtctatgtt
     4381 tatatggttt tctcccatca gggggatggt atatacacaa acgacgtgag tgactgttgt
     4441 atatccaggg aaagggcaat gcgaaggcct gaataaagga tatacaaaca tagttactca
     4501 cgtttttttt tattgtttaa cctttaaata atttgtgtat atgaaacaga acaaaccaga
     4561 cggtagagaa gcatacatca ctccgtctat cgaagttatc aaaatggaga atgaaggagt
     4621 cattgcaaca agcggcgaac cttaccatcc cattacgcgc tcctattcgg gcagcacctc
     4681 tacccatagc tacaattcgg catccagcag cgacttggaa gacctaatca atgacatctt
     4741 aaccgtagaa aactaagggg gacttcatta tgatgaaatt aagaaacctt atgcaagttg
     4801 cctgcatggc aactgctgcc ttgaccgcat tcagttgcag ccaagaggaa tttgaaaaca
     4861 gcgggcggaa aggaaacatc accgttaacg caacgtttga aggcgcaggt accgacaccc
     4921 gtactaccgt aaacgatgaa tacaagattc tatggcaaga taccgatgcc ctagggttgt
     4981 tctgtagtaa tgcagaaagt aattatagca atacaaaatt agaatatgca agcggtgctg
     5041 gtcaaacttc cgccactttc aacggcagca agccaagcgg agaaacggct gtattctcca
     5101 tctatcctta ccaacaaaac atgagcgtaa gcggcaatac attgaccatg actctacctg
     5161 ccacgcttac aaattataac ggcagcagca atggcccgat gtatgccaag gtgacaaatc
     5221 ccgacaatct gagcgctctg tccttcaagc acatggcagc catgataaaa ctgaccgtca
     5281 acaagattcc ggcagaggcc actactttca agattattgc ctccaataac attgcaggta
     5341 cttgtacggt agacttaacc gcagcagacc cgatactggc agtaacgagc gatgaaagca
     5401 aggaaatcac cgcctccttc acagcctcag ctgatataaa gtctcgcaac ttctacattc
     5461 ctttgcccac aggtacttat agttccatca ctgcccaact gacgaatgga agcgacaagg
     5521 tatattttac caagacgctt aatgacaaaa tcctaggcag aagagacata ttggtagtac
     5581 ctcctttgga ttgcgttgtg gtagaggcta caacccccag tgcgcttagt acagctttag
     5641 ctgattcaaa aaatctccca caagaagcac cgacagcagc aaccgtaacc gacattgcag
     5701 tcagcggcag cttcaatacc acttccggca gcaacgacgg catcgccatc ccggttttac
     5761 agaactcgga catcaacctg gcgttcaata cagccccaac gaccagtact gccgctccgt
     5821 tgacgctgac cgacaagacc aataccagca taggtgctcc cgccgccact gccaccaaca
     5881 gtgtatcctt ggctgtgccg gaaaccaatg cagagcaaga agctccttct gtagccatca
     5941 ccatgccaag caccaccgtt acattggcag cagtaggcaa taaagccact tacaatgaag
     6001 tgactgccac taccgcccag cagacattga ttatcaatgc aggcgtcacc gtaaagaagc
     6061 tgaccgtaaa aggcggtaac ttgaagatat atggaaaggt agaacaattg gtacacgatg
     6121 ccggcgatac cacaatctat ataataaaag gaaccgaagc atcacttccg gcaacaatcg
     6181 acagcaaatt tgtagttcaa tccgacgtgg cagtcctaaa ggccgctttc gccaacggcg
     6241 aagattttaa attgtccgcc gatgccgaca tcacagggca aagcgtcagt gtacccgccg
     6301 gaaagtccgt ggttcttgac ttgaacggat atacactgac tgccgacaac agcgcaacag
     6361 gcaaaatcat cgtcttgggc aagatgacac tgaaggacag ctctaccgag aagaaaggca
     6421 agatagttgc cagccaggat tatacagcgg cttcttataa tggcagtctg attgaaatag
     6481 ccggtgaaga tgcctccatg accatggaaa gcggcaacat cagtgcagtc agaaagactc
     6541 cgaacagtaa cggccaatat ggcgtcggag tgacggacgg tggagacttc accatgacag
     6601 gcggcaagat agaagccgga tggtttgcag tggcaggcaa cggcaattac aagacgcaga
     6661 actccatcat caacatcaca gacggagaac tcatttctac tgctgactat gcagtctatc
     6721 tgccccaatc cggcacaacg accatcagtg gcggcaaggt ttatggtgcc gcaggaggtg
     6781 tatgcatcca acgaggcact ctgaacgtgg aaggcacagc cttgattacc agtaaaggca
     6841 caggcagcac cggcaactgg ggcgacggta ccggaggact ggactgcgcc gccatcaacg
     6901 taagtggagc atatggcatt gccacagtaa acatcaaagg cggtacactg attgccgaag
     6961 caaagtcact catcacagaa ggcaccactt atacaccggt catcaacgtt accggcggta
     7021 cattctccga cccaagcgcg ctgaagtaca tgaagacaaa tgcaaatgtg aacataaagt
     7081 tgaccgccga caagacctgc ccgggattca agaccacaag cggacaaacc ttgacgatgg
     7141 acttaggcgg caagatcctt acacttgctg acccgaccgt aggttccacc ggcaccgaaa
     7201 cgaacagctg tcaattactc gaaggttcaa acgttacttt caagaacgga acgctgaaga
     7261 gtgacaacaa caaaatcatg attcagaact actgcaacct gacattagat aatatgacag
     7321 tagaagacac aaatgcccaa tacgtagtaa gcaacaattg tggcaatata agcatcaaca
     7381 ataccactat caacgcagga agcaatgcga atcaatttgc attcgacgta tgcggctatg
     7441 caaagtacac tgctggagtc acggttacgg taagcggtac gagcgtcatc aatggaaaag
     7501 tggaaatttc caagagtgca ggaaataccg aacctatgaa gctgaatatc acaggcggta
     7561 ctttcaacgg tgacttaaag gtagatgcat ccgtgggaac cgaaaatgcc aaaagtatca
     7621 tctctgtttc cggaggtaca ttctccgacc caagcgtact gaagtacatg gcaaccaacg
     7681 caactgtgga tataaaactt ctctcaaata tcaacatcgc caagacggag cttgccacag
     7741 gctacatatt gaatgctgca aacgcaacgg caaacttaaa cctgaatggc cacgacatca
     7801 tcaattcctc agaaacagct gatgccactc ctttcacaca aatctttact gtacagaacg
     7861 gaacactaaa catttcaggc aacggcaatg tgaagtgcga tgcatctgct acagcgaaag
     7921 acgatggtta tcgcatggta attgaagccc gaggacacgg gacagtaaat attcatggcg
     7981 gttcttacta taacacccag aaactgaaca cccagataga cctgatttat gcaagagaga
     8041 atgggaaaat caatatctat ggaggaacat ttgaatccgg caaatatggt acacccaaca
     8101 acgacacgga tggcagatac tgggtactga acttaaagaa tacagacaag aacactgcca
     8161 gcatccaggt gtccggtgga acgttcatca atttcaaccc ggcaaatccg aatatggacg
     8221 acaatgaatc ctatttggta acaggttacg aggttacccg tgacggcagt gtatatacag
     8281 cagcccacaa agtcaacgat gggaggaaag aatatattgt tggcccaaca agtcaggaga
     8341 accgataagc caaattctaa gaaaggaagc aatatatcct cgcagaccaa acgaagaggt
     8401 atcggaatcg ccttattact atcttttaga tgcggcggac agcggatttt cttttataaa
     8461 tctgcgtcct ccgcgtctaa aaaatgacaa caagacagtt gaaaaatctc tcaaatcttc
     8521 ctcattcaca caaacattca ttatttttct gagtagccca aagtatcatg aataacaact
     8581 aacaatcaaa acatatgaga atacagatat tggattatca agtaggaccg cacaccttcc
     8641 gcatggtgaa accttccgac ttcaatatat tcaaggcgtt gccttcactg attccgttca
     8701 tcacgacaat agacacgacg caaaaagtaa tctttgaaac agagatagac gatgacgaaa
     8761 cagcgacaaa acgaaccata gcgaaaactc ccgatgatat atgtttcaac tgggaagatg
     8821 ccgattgcat cattcgccct ttgccccaca gctcacacct tgtatccatc accccacgga
     8881 aaagcgggaa aaactattgg atggagtgca acgataactt caggcaatgc ttcatccacc
     8941 taccggcctg caggacagaa acaccggctc cggaaaacga aacgaacttc gtactgaaca
     9001 acttcttgat gatgctctat gccttcaatg ccgcccgcca ccatacactg ctgatgcatg
     9061 cctcggttgt cgctactgaa acaggcaaag gctacctctt cttagggaaa agcggcacgg
     9121 gcaaaagtac gcacaccggg ctctggctgc aacagttctc ggactgccat ctactgaacg
     9181 atgacaatcc gatagtacat gtggacagcc tcggcaagca agccactgtt ttcggttctc
     9241 cgtggagcgg aaagacacca tgctatcgga aagaatccat gaccgtaggc gccttcgtcc
     9301 gcttggaaca agcaccgcag aatgaaatag agcaagagag agcagcacat gctttcgcca
     9361 ccctcctccc ctcctgctct tgcctaaagc agaacaagga aatctataac gccattgtcg
     9421 ccactgtgac ggaacttgcc acgctggcac ccgtctatca tctgaaatgc ctacccgacc
     9481 gtgaagcgac ggaactttgc agaaagacgg tagaaggata agttatgaat gatgaactga
     9541 acagccgatg aagaaaagca ttcccaacga gatattgctt cccgaagtgg cgcgtctcat
     9601 caaagaggga catacagtaa ccatcaccgt gcggggcaac agcatgaatc ctttcttagt
     9661 ggaccgccgt gaccgggtga cactgggcga tttcaccaca gaacagctgc aaccgggcgt
     9721 caccgtactg gcacgcgacc tgacggaacg catcgtcttt caccgcatca tccgtcggaa
     9781 cggagacata ctcatcctgc aaggcgacgg caacctcgcc cagaccgaag aaaccgacat
     9841 cggacgggta atgggcgtca tgaccgaagc catgcgaaaa gacaaacggt acaccgccga
     9901 cggcaaagtc tggaagctct actcctactg gtggatgaag ctaaaccccg ctcgccgctg
     9961 gctgctcgcc ctgttcagaa gaatataaaa caaaataacc atgaaaatca aacaaggatt
    10021 tatcctgcac cggataggcg atgactacat catcatgcaa gacggctcgt cgaacgtgga
    10081 cttcagcaaa gtcatcagcc tgaaccaaac ttccgccatg ctttggcaag agatagaaaa
    10141 caaagagttc gatacagaca gcgtgacaga agccctgacc agccgctatg atgtagataa
    10201 cgaatcggcc cgtcgcgatg cgcagaagtt tatcgactcc cttgaccgcg aaggaatcat
    10261 agaataagga cggatatgca acacgctttc ttttcattgg tacgctccgg cctgtggggc
    10321 actccggcag accgacaact cttccggtcg gtctcgccgg acgactggga aaccgtgtac
    10381 cgcatggcaa actcacaagc cctgcttgca ctgacttttg acggcataag cagtctgccg
    10441 gccgaactgc gccctccacg cgtcctctat ctgaaatggg ctgcccggac tgcacagata
    10501 gaacaagcca acaaacgcct caaccagctt ctgcccgaac tcaataccct ttaccgggaa
    10561 gccgggctgc atcccgtact gctgaaaggg caaggcatcg gcaccaacta ccgcactccc
    10621 ttgcaccggc aatgcggaga catcgacatc tatttaggaa aacaagggca acccatagcc
    10681 aacc
//
