LOCUS       c00175_gnlPro..        14171 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EIKHKFCI_175.
ACCESSION   c00175_gnlPro..
VERSION     c00175_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:49:52
            Original ID  :: gnl|Prokka|EIKHKFCI_175
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14171
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14171
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1327:4171]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1328..4171
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..14171
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14171
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             complement(3..992)
                     /locus_tag="ctg175_1"
                     /transl_table=11
                     /translation="MNNRDRFGNQIDPNTQPDNLEDSTNTEIQSLPPKLYMWKLSETLG
                     NRTIIPADTASLNFQSTNLVEGMFGHYNYLGNLGSPRLSRLFFEREESEPTIFMAPFSS
                     FFTRPDQVLFTNSNVPYTNLTYYKAGSKVNGEERFKSYFSVNVNKQLAFGFNIDYLYGR
                     GYYQNQSTSHFNAGLFGSYIGEKYQVQAVYNNFFLKMNENGGIADDQYITRPENMSGGK
                     KEYESTTIPVKLEQSSNRNKDFYIYLTQRYRLGFTRRVRNTQEGKPTVSAPKASSSPSS
                     EAEISASNNDIALPNDSIASKSVSTLAAANDSLPSVSTADNDSLFEEEF"
     CDS             complement(967..1248)
                     /locus_tag="ctg175_2"
                     /transl_table=11
                     /translation="VILIYCKGLFHFKPEKVWIQGQRTGSSIEQNRKQDSLKEAKKAEF
                     SKQIIFYCIFAPNYETNCTDIYISVRYRDMGGYGAKHLKPDEQSRPVR"
     CDS             complement(1328..1873)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg175_3"
                     /sec_met_domain="POR (E-value: 2.5e-36, bitscore: 116.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVTWMPAYGPEQRG
                     GTANVTVIVSDEKISSPILSKYDAAIILNQPSLEKFESKVKPGGVLIYDGYGIINPPTR
                     KDIHVYRINAMDAANEMNNAKAFNMIVLGGLLKIKPMVTLDSVLRGLKKTLPERHHHLI
                     PMNEEAIKKGMELIQGMK"
     CDS             complement(1896..2657)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg175_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.3e-26, bitscore:
                     83.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEDIIKPENLVAKKPTLMNDNPMHYCPGCSHGVVHKLVAEVIE
                     EMGLEDKAIGISPVGCAVFIYNYIDIDWQEAAHGRAPALATAIKRLWPDRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKTSTSPYGRDVHLH
                     GYPLKMADIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMAGKGSNLVEIVSTC
                     NSGWKMSPAKSNEWMVENMFPFYPLGDLKDK"
     CDS             complement(2669..2842)
                     /locus_tag="ctg175_5"
                     /transl_table=11
                     /translation="MNPDKIRNVLNILFMVLALAAIIIYFAAKDDFKLFIYVCGAAIFV
                     KLMEFFIRFTNR"
     CDS             complement(2839..3924)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg175_6"
                     /sec_met_domain="PFOR_II (E-value: 4.1e-28, bitscore: 88.7,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 4.1e-49, bitscore: 158.3,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRCGADGYFGYPITPQSEVLETLAELK
                     PWETTGMVVLQAESEVAAINMVYGGAGSGKMVMTSSSSPGVSLKQEGISYLAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLIALAPASVQEMADFVGLAFELAFK
                     YRNPAIILADGVIGQMMEKVVLPVQKPRRTDAEVIEQCPWATTGRTNGRKPNVITSLEL
                     KPEEMEKNNIRFQAKYKQIEENEVRFEEIHCDDADYLIVAFGSMARIGQKAMELAREEG
                     IKVGMLRPITLWPFPTKVIAAYADKVKGMLVTELNAGQMVEDVRLAVNGKVKVEHFGRL
                     GGIVPDPDEIVDALKEKLIKK"
     CDS             complement(3944..4171)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg175_7"
                     /sec_met_domain="Fer4_7 (E-value: 3e-13, bitscore: 41.2,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 7e-09, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.1e-08, bitscore: 25.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.7e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLNVIALTKEVNVKGYNYAH
                     QILEDTCNGCASCATVCPDGCISVYKIKVE"
     CDS             complement(4188..4463)
                     /locus_tag="ctg175_8"
                     /transl_table=11
                     /translation="MERLNTIKELINQGNVEQAIQQLDEILQTDFPGKDEAYYLRGNAY
                     RKQGNWQQALNNYQYAIDLNPESPAQHAYQMAMDILNFYNKDMYNQ"
     CDS             complement(4639..5076)
                     /locus_tag="ctg175_9"
                     /transl_table=11
                     /translation="MKTIGICSDHAGFELKEYVRGWLEAKGWAYKDFGTYSTESCDYPD
                     FAHPLALAVEAGECYPGIAICGSGEGISITLNKHQGIRAALCWTAEIAHLARQHNDANV
                     LVMPGRFISTEEADMIMREFFSTPFEGGRHQRRVDKIPVHL"
     CDS             complement(5168..7159)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg175_10"
                     /sec_met_domain="Transket_pyr (E-value: 2.6e-35, bitscore:
                     112.7, seeds: 81, tool: rule-based-clusters)"
                     /sec_met_domain="Transketolase_N (E-value: 9.9e-94,
                     bitscore: 304.9, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLVYD
                     PENPAWEGRDRFFLDPGHMSPMLYSTLALTGKFTLDELKEFRQWGSPTPGHPERDIMRG
                     IENTSGPLGQGHTFAVGAAIAAKFMKARFEEVMPQTIYAYISDGGIQEEISQGSGRIAG
                     ALGLDNLIMFYDANDIQLSTETKDVTIEDTGKKYEAWGWKVIKINGNDPDAIRGALNEA
                     KAEKECPTLIIGHTVMGKGARKADGSSYEADCATHGAPLGGDAYINTIKNLGGDPTNPF
                     VIFPEVAELYAKRATELKKIMAEKYAAKAVWAKANPEKAAKLEMFFSGKAPEVNWAAIE
                     QKAGVATRAASATVLSALATQVENMIVASADLSNSDKTDGFLKKTHAFKKGDFSGAFFQ
                     AGVAELTMACCCIGMALHGGVIPACGTFFVFSDYMKPAVRMAALMEVPVKFIWTHDAFR
                     VGEDGPTHEPVEQEAQIRLMEKLKNHKGHNSMLVLRPADAEETTVAWKLAMENTTTPTG
                     LIFSRQNIANLPEGNDYEQAAKGAYIVAGSDENPNIILVASGSEVATLVAGTELLRKDG
                     IKVRIVSVPSEGLFRSQAPGYQEGIIPCGAKVFGLTAGLPVTLQGLVGPRGKVWGLESF
                     GFSAPYKVLDEKLGFTAENVYKQVKAML"
     CDS             complement(7368..7598)
                     /locus_tag="ctg175_11"
                     /transl_table=11
                     /translation="MSNVDADNAQEVTINLSGTKAKKAVGEILTSTNLTDYNSFENPDN
                     VKPVPFKEVKINKDILKIKLPAKSIVTIELQ"
     CDS             7605..8831
                     /locus_tag="ctg175_12"
                     /transl_table=11
                     /translation="VYLAVWVFGGGSADHWYSAVVAYIHHVAVQLKRNVGGILVYIVHF
                     EYIISGGEYHVFSAGQNHGLQYIDDLGNVCHFQTVGIFMEDVEAEGSDKSITQCILLVQ
                     MSGIGTRFSVPPGSPFVKHKSHVLLRVVFIHNGAMLLDDIFYFAAFAQCPVIVVFTELG
                     GGAFTAVPSADGIVVQGKTVHTAAYAVHQHFGPVIVVVAGTAGYLEKTIAVIVAAVGGI
                     AAVEVGIIFGTHASTATPAFVTHAEVFYFPGFVATVLAAQACHGGVSFGGHVFHPFGKF
                     FYGTTAYVSTDIGFTSQHFAEIEELMGSETVVFDSASPVVVHHFGAVFFRADTVHPVVF
                     IGKAASRPAKDGYTELLQCIEYVGAITVDVGNIGVFTYPKSTIDTSSQMLCKLAVDFFG
                     NDLPALVCV"
     CDS             complement(8936..9526)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg175_13"
                     /sec_met_domain="FGGY_C (E-value: 2.4e-20, bitscore: 64.1,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIPVDMDEIYGKLYNHALTGNADCGGLISYNYISGEPITGLAAG
                     RPLFVRSANDKFNLANFMRTHLYASVGVLKIGNDILFNEEKIRVDRITGHGGLFKTKGV
                     GQRILAAAINSPISVMETAGEGGAWGIALLASYLANNGNDQSLADFLDKHVFTGNAGIE
                     ISPTAEDVSGFNTYIESYKAGLPIEEAAVRFKN"
     CDS             9797..10150
                     /locus_tag="ctg175_14"
                     /transl_table=11
                     /translation="MSRYVEATGSFGSKEACVFTGRQYLRQNIPKFPVVSFRSNKFVEL
                     IHHFRRIVFGDGIDGEHTGGISYAQYLLAGYLPVDKTCKGGQVIDGWNVLFIIQDGLVE
                     VGDAPTQRDVVDK"
     CDS             10247..10393
                     /locus_tag="ctg175_15"
                     /transl_table=11
                     /translation="VHHGTDTDGCQGFYLCIVEALYIGTKVCVAILQPIPDSLDAICPQ
                     SVD"
     CDS             11304..11867
                     /locus_tag="ctg175_16"
                     /transl_table=11
                     /translation="LVKVAQIVEVGGEAFGTRVFQHAANGDFGLGGVPYFGVGFRTCVF
                     QFGSVVVELEVFCYECLHVLVADSIVVCHHIIDGIVVHMIAQYLFGADLVTVCHSHVVH
                     LVAEADDEHILRISPCGSYAHPCGNLVLGFFVLPVAYYHFAVLSHTCHNVSELAVAVSR
                     LVQVHKIHVHRLPGNFLVELCMEV"
     CDS             complement(12206..12892)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldolase_II"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg175_17"
                     /sec_met_domain="Aldolase_II (E-value: 2.3e-53, bitscore:
                     171.8, seeds: 389, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEALKDKVFHANLELVKHGLVIFTWGNVSGIDRESGLVVIKPSG
                     VSYDEMKAEDMVVVNLDGKVVEGRLKPSSDTPTHLVLYKAFPEIGGVVHTHSTYATAWA
                     QAGCDIPNIGTTHADYFHDAIPCTADMTKEEVEGAYELETGNVIVKRFEGLNPVHTPGV
                     LVKNHGPFSWGKDAHEAVHNAVVMEQVAKMASIAYAVNPNLTMNPLLIEKHFSRKHGPN
                     AYYGQK"
     CDS             complement(12935..13612)
                     /locus_tag="ctg175_18"
                     /transl_table=11
                     /translation="MSNYYSSNPKLYVGIDCIIFGFNEGELNLLLLKRNFEPAMGEWSL
                     MGGFVQEDESVDDAAKRVLNELTGLEDVYMEQVQAFGAIDRDPGERVVSIVYYALININ
                     EYDKESVQQHNAFWVNINELPALIFDHPQMVEKARKLMQQKASTEPIGFNLLPKLFTLS
                     QLQSLYEAIYGESIDKRNFRKRIAEMDYIEKTDKIDKTGSKRGAALYQFNEKAYRKAPK
                     FKL"
ORIGIN
        1 acgaactctt cttcgaaaag tgagtcgttg tctgcggtag aaacagacgg caggctgtca
       61 ttggcagctg caagtgtgct gaccgatttt gatgctatgc tgtcgtttgg caatgctatg
      121 tcgttgttcg aagcggatat ttcggcttca gaggacgggg aggatgaggc tttgggtgcg
      181 gataccgtcg gtttgccttc ttgtgtgttc cgtactctcc gcgtaaaacc aagacgatag
      241 cgctgtgtca gatagatata aaaatccttg ttacggttgg aactctgttc caatttgacc
      301 ggaatagtgg tggactcgta ctctttcttt cctccggaca tgttttcggg acgggtgatg
      361 tattggtcgt ctgcaatacc gccgttctcg ttcatcttca ggaaaaagtt gttgtagact
      421 gcttgtacct ggtatttctc gccgatatag ctaccgaaca gacctgcatt gaagtgcgag
      481 gtggactggt tctggtaata accgcgtccg tatagatagt cgatgttaaa gccaaatgcc
      541 aactgcttgt tgacgttgac ggagaagtag gacttgaagc gttcttcacc gttcactttg
      601 ctgccggctt tgtagtaggt aagattggtg taaggcacgt tgctgttggt gaaaagcacc
      661 tggtcgggac gtgtgaaaaa actggagaag ggagccatga agatggtagg ttcgctttcc
      721 tcccgttcga agaacagacg tgagaggcgt ggagaaccta aatttcccaa gtagttgtaa
      781 tggccgaaca ttccttccac cagattggtg ctctggaagt tgaggctggc tgtgtcggca
      841 ggtatgatgg tacggttgcc cagtgtctca cttagtttcc acatgtaaag cttgggtgga
      901 agactttgaa tctcagtatt ggtactgtct tccagattgt ccggctgggt attcgggtca
      961 atctggttac cgaaccggtc gcgattgttc atcgggttta aggtgttttg cgccatagcc
     1021 ccccatatcc ctataacgga cagaaatata tatgtcagta caattcgtct cataattagg
     1081 cgcaaagata caataaaaaa ttatttgctt actgaattca gccttttttg cttcttttaa
     1141 actgtcttgt tttctgtttt gttctatact gcttccggtt ctctgccctt gaatccatac
     1201 tttttccggc ttgaaatgaa ataagccctt gcaataaatc aatatcacaa gggcttatcc
     1261 gttttccttt atctcttatt ctggcgtaaa gttcctcctc ttatggggag tggctttaca
     1321 tagcctttca tttcattccc tgaataagtt ccattccttt cttgatagct tcttcgttca
     1381 tcggtatcaa gtggtggtgg cgttcgggca gtgtcttctt caatcctctg agtacactgt
     1441 ccagtgtaac catcggcttg attttcaata atccacccaa tacaatcatg ttgaatgcct
     1501 tggcgttgtt catttcattg gcggcatcca tggcgttgat gcggtaaacg tggatgtcct
     1561 tacgcgtcgg cgggttgatg atgccgtaac cgtcgtagat aagtacgcct ccgggtttta
     1621 ccttgctttc gaatttctcc aatgacggct ggttcaggat gatggcggca tcgtacttgc
     1681 ttaagatggg tgaggatatt ttctcgtcac ttacgatgac tgttacgttg gctgtaccac
     1741 cacgttgttc cggtccgtaa gccggcatcc aagtcacctc tttgccttcc atcaatccgg
     1801 aatatgccaa aatctttccc atggacaata caccttgtcc accgaagcct gctataatga
     1861 tttcttcttt cattgttctt ctgtctttag catgattatt tatctttcag gtcgcccagc
     1921 ggatagaagg ggaacatgtt ctctaccatc cattcattgg atttcgcagg agacatcttc
     1981 cagccggagt tacaggtgga aacgatttcc acaaggttgg aacctttgcc tgccatagag
     2041 ttctcgaatg ctttgcggat agcctttttc gctttgcgga tggcgggaac ggactgtacg
     2101 ctttggcgtg tcacgtaagc ggttccttcc aattgtgcag caatatcggc catcttcagc
     2161 ggatagccgt gcagatgcac gtcacgtccg taagggctgg tcgatgtctt catgcctaca
     2221 agggtagtgg gagccatttg tcccccggtc ataccataga tggcattgtt gatgaagatg
     2281 atggtgatgt tttcgccgcg gttcaaggcg tggatggttt cggcagtacc gatacaagcc
     2341 aggtcgccgt ctccttggta agtgaacacc aggcggtctg gccaaaggcg cttgatggca
     2401 gtggcaagtg cgggcgcacg tccatgggcg gcttcctgcc agtcgatgtc tatataatta
     2461 tagatgaaca cggcacatcc cacgggggag atgcctattg ctttgtcttc cagtcccatt
     2521 tcttcgataa cttcggctac gagtttatga actacgccgt gactgcatcc cgggcagtag
     2581 tgcatgggat tgtcgttcat cagagtcggt ttcttggcaa ccagattctc gggctttata
     2641 atatcttctt ttgtcataat cacttctcct atctgttggt gaaccgtatg aaaaactcca
     2701 tcaacttgac gaatatcgcc gcgccgcaga cgtagatgaa cagcttgaag tcatcttttg
     2761 cagcaaaata tataatgata gctgccaggg caagtaccat gaagagaatg ttcagtacgt
     2821 ttcttatttt atcaggattc atttcttaat cagtttttct ttcaatgcat ctactatctc
     2881 atccggatcg ggaacaatgc cgccgaggcg tccgaaatgt tccactttca ctttaccgtt
     2941 cacggcaagg cggacatctt ccaccatctg tccggcattc aattctgtaa cgagcatacc
     3001 tttcaccttg tcggcatacg cggcaatgac tttggtcggg aacggccaca acgtgatggg
     3061 gcggagcata cctaccttta ttccttcttc gcgtgccagc tccattgctt tctgtccgat
     3121 gcgtgccata gagccgaagg ctacaatcag gtagtcggca tcatcgcaat gaatttcctc
     3181 gaagcgaacc tcattctctt ctatctgctt gtatttggcc tggaaacgga tgttgttctt
     3241 ttccatttct tccggtttca gttccaatga ggtgatgacg ttgggtttgc ggccattggt
     3301 tctgccggta gtggcccatg ggcattgttc gatgacttcc gcatcggtgc ggcgtggctt
     3361 ttgtaccggg agcaccactt tttccatcat ctggccgatg acaccgtcgg caaggatgat
     3421 tgccggatta cggtatttga aggcaagttc gaatgccagt cctacgaaat ctgccatttc
     3481 ttgtacggaa gccggagcaa gggcaatcag acgatagtca ccgtggccgc ctccttttac
     3541 tgtctggaaa tagtcggcct ggctcggttg gatggttccc agaccgggac cgccgcgcat
     3601 aacgtttaca atcaagcaag gcagctcggc acctgccaga taagagatac cttcctgctt
     3661 taggctgaca ccggggctgg aggaggaggt catgaccatt ttaccacttc cggcaccgcc
     3721 gtacaccata ttgatagctg ccacttcact ttctgcctga agaaccacca tgccggtcgt
     3781 ctcccagggt ttcagttcgg caagagtttc caatacctcc gattgcggag taatgggata
     3841 tccgaagtaa ccgtctgcac cgcaacggat ggctgcgtgg gcgatggctt cgtttccttt
     3901 cattaataca acttcttctg ccatattcta ctgatttaca gatttattct acttttattt
     3961 tatatactga gatacatccg tccggacata ctgtggcgca cgaggcgcag ccgttacaag
     4021 tatcttccaa tatttggtgg gcatagttat accctttcac attcacctcc ttggtgaggg
     4081 ctattacgtt gagcggacac gctaccacac acaagttgca gcctttgcaa cgttcggtgt
     4141 ctactacgat tgctcctttg atttttgcca taatttacgt tctttattta ttgattgtac
     4201 atatccttgt tgtagaagtt caggatgtcc atagccattt gataggcatg ttgtgccggg
     4261 ctttcggggt tcaggtcgat ggcatactga tagttgttca gtgcttgttg ccagttgcct
     4321 tgtttccgat aggcatttcc ccgcaggtag taagcttcgt ctttgccggg aaagtctgtt
     4381 tgcagtattt cgtcaagctg ctggatggct tgctctacat ttccctggtt gataagctct
     4441 tttatggtat tcagtcgttc catatctaaa aaatatccgg gttatcgaac cacaaagata
     4501 gtttttattt gaagacaatg agcatcttca ctgtgaaaaa taagaaaaag gggcaaataa
     4561 aaagcccgaa gtttctcacg attctatcag aatgtcagag cttcgggcgg atatcataaa
     4621 gaaggtgatt ctattgcttt acaagtgtac cggtatcttg tccactcttc gttggtggcg
     4681 tccgccttcg aatggtgtac tgaagaattc cctcataatc atgtcggctt cttcggtact
     4741 gatgaatcgc cctggcatga caagcacatt ggcatcattg tgctggcgtg ccaaatgggc
     4801 tatttctgcc gtccagcaga gggctgcgcg gataccctga tgcttgttca gcgttatgct
     4861 gataccttca ccgcttccgc agatggcaat tcccggatag cactctccgg cttcaacggc
     4921 cagtgccaaa ggatgtgcaa agtcgggata gtcgcaactc tcggttgagt aggtcccgaa
     4981 gtccttgtaa gcccagcctt tggcttccaa ccagccgcga acatattcct tcaattcgaa
     5041 gcctgcatgg tcggaacaga ttcctattgt tttcatgatg gtcagttaat ataccaatgt
     5101 gccaatgtgc tgatgcctgc agcttgtagg gcgcgggcaa tcagcacatc agcacattgg
     5161 ataatgatta taacattgct tttacttgtt tgtaaacgtt ctctgcggtg aaaccgagct
     5221 tttcgtccag cactttataa ggtgccgaga atccgaatga ttccaatccc catactttac
     5281 cgcggggacc taccagccct tgcagtgtga cgggcagacc ggctgtcagg ccgaatacct
     5341 tggcaccaca cgggataatg ccttcttgat atcccggagc ttggctacgg aacagacctt
     5401 cggaaggaac ggacacgata cgcaccttga tgccatcctt gcgcagcaat tcagtaccgg
     5461 ctaccaatgt ggcaacttcc gagcctgaag caacgaggat tatatttgga ttttcatcgg
     5521 agccggctac aatataagcg cctttggcag cttgttcgta atcgttgcct tcgggcaggt
     5581 tggcgatgtt ctggcgggag aaaatcaaac cggttggggt tgtggtattt tccattgcca
     5641 gtttccatgc cacagttgtt tcttctgcat ctgccgggcg gagtaccaac atggaattat
     5701 gtcccttgtg gtttttcagt ttttccatca ggcggatttg ggcttcctgc tctaccggtt
     5761 catgggtagg accgtcttca cctacacgga aggcatcgtg tgtccagatg aacttcacgg
     5821 gaacttccat cagggctgcc atacgtacgg caggtttcat gtagtcggag aatacgaaga
     5881 aagttccgca agcggggatt acaccgccat gcagtgccat accgatacag caacatgcca
     5941 tagtcagctc ggcaacaccg gcctggaaga atgcaccgct gaagtcacct ttcttgaagg
     6001 catgtgtttt cttgaggaat ccgtctgtct tgtcggaatt ggaaaggtcg gcagaagcaa
     6061 caatcatatt ttctacttga gtggcgagag cactgagcac agtggcagat gctgcgcggg
     6121 tggcaacgcc tgctttctgt tcgatggcgg cccaattcac ttcgggagcc ttgccggaga
     6181 agaacatttc cagtttggca gccttttccg gattggcttt tgcccatacg gctttggctg
     6241 catacttttc agccatgatt ttcttcagct cagttgcacg cttggcatat agttcggcca
     6301 cttcggggaa gatgacaaac ggatttgtcg ggtcaccacc caaattcttg atagtgttta
     6361 tataagcgtc gccgcccaga ggagcaccgt gcgtggcaca atcagcttcg tagctgctgc
     6421 cgtctgcctt gcgggcacct ttacccatta cggtatggcc gataatcagc gtcggacact
     6481 ctttctcagc tttggcttcg ttcagtgcac cgcggatggc atcgggatcg ttaccattga
     6541 ttttaatgac tttccagccc caagcttcgt atttcttgcc ggtatcttcg atggtcacat
     6601 cctttgtctc ggtagaaagc tgaatgtcgt tggcatcata gaacatgatg agattatcca
     6661 accctaatgc tccggcgata cggcctgagc cttgggagat ttcttcctgg atgccaccgt
     6721 cagaaatata agcgtagatg gtctgtggca ttacttcttc gaaacgtgcc ttcatgaact
     6781 tggctgcgat ggctgcaccg actgcaaatg tgtgtccctg gccgagcggt ccggaagtgt
     6841 tttcgatgcc gcgcatgatg tcacgttcgg gatgtcccgg agtagggctt ccccattggc
     6901 ggaactcttt cagttcgtcc agcgtgaact tgccggtcag ggccaatgta gagtaaagca
     6961 tcggtgacat gtgtcccggg tcgaggaaga aacggtcacg accttcccaa gccggatttt
     7021 cagggtcata taccaggaac tctgagaaga gtacatttac aaagtcagca ccacccatgg
     7081 caccgcccgg atgcccggag ttggctttct caaccatgga tgcagcaagg atacggatat
     7141 tgtccgccgc acggttcata agtttgttgt cgttcatatt gaatctaatt aattttgaat
     7201 attatcaata ggttatttgg tccttgtagg ttttccaagg gcaaagataa ctctttatgc
     7261 gtaattcaca acactcgaag agtgtctttt ttatcagtat tactgccttt ttgctgctaa
     7321 aatgatacta aacgtattta gctgattttg tgcggtgcac ggtagtttta ctgtaactca
     7381 atagtaacga ttgatttggc cggaagttta atcttgagaa tatctttatt gatttttacc
     7441 tctttgaacg gaacgggttt cacattgtcg ggattttcaa atgaattgta gtccgtcaga
     7501 ttggtggaag tcaatatttc accaactgct ttcttggctt tcgttccaga cagattgatg
     7561 gtcacttcct gtgcattgtc tgcatctacg ttggacatgg aaatgtgtat cttgccgttt
     7621 gggtctttgg aggcggtagc gctgaccatt ggtattctgc ggttgtcgcg tacatccatc
     7681 atgtcgcagt tcagctcaag aggaatgtag gtggcatcct ggtgtacatt gtacattttg
     7741 aatacataat aagtgggggt gagtaccatg ttttttccgc tggtcagaat catggattgc
     7801 aatacattga cgatttgggc aatgtttgcc attttcagac ggtcggtata tttatggaag
     7861 atgtcgaagc tgagggaagc gacaaaagca tcacgcaatg tattctgttg gtacagatgt
     7921 ccgggattgg tacccggttc agtgtcccac caggttcccc attcgtcaag cataagagcc
     7981 acgttctttt gagggtcgta ttcatccata atggtgcaat gcttcttgat gacatcttct
     8041 atttcgcggc atttgcccag tgtccagtaa tagtcgtctt tactgaattg ggtggcggcg
     8101 cctttactgc cgttccatcc gctgacggta tagtagtgca aggaaagacc gtgcatacgg
     8161 ccgcctacgc ggtccatcag cactttggtc cagttatagt cgtagtcgct ggcaccgctg
     8221 gctatcttga aaagactatt gccgtcatag ttgcggcagt aggtggaata gcggcggtag
     8281 aggtcggcat aatattcggg acgcatgctt ccaccgcaac cccagctttc gttacccacg
     8341 ccgaggtatt ttactttcca ggctttgtcg cgaccgttct ggcggcgcag gcgtgccatg
     8401 ggggagtctc cttcggaggt catgtattcc acccatttgg caagttcttc tacggtacca
     8461 ctgcctacgt ttccactgat atagggttca catcccagca tttcgcagag attgaggaac
     8521 tcatgggttc cgaaactgtt gtcttcgata gtgcctcccc agttgttgtt caccattttg
     8581 gggcggtttt ctttagggcc gataccgtcc atccagtggt attcatcggc aaagcagcct
     8641 cccggccagc gaaggacggg tacacggagc tccttcagtg cattgaatac gtcggtgcga
     8701 taaccgttga tgttgggaat atcggagttt tcacctaccc aaagtccacc atagatacaa
     8761 gttcccaaat gctctgcaaa ttggccgtag atttctttgg gaatgatttg cccgctctgg
     8821 tctgtgtgta aagtgatagt ggcacttttc tgtgcgaaga gtgacaacga ggtggagaga
     8881 aatatgctac tgataaataa ctttgtgttc atagtttttt agtgttatta aatacttagt
     8941 tcttgaatct tactgctgct tcttcgatgg gcaaaccagc tttatagctt tcgatgtagg
     9001 tgttgaatcc gcttacatct tcagctgtcg gtgagatttc aataccggca tttccggtga
     9061 atacatgctt gtccaggaag tcggcaaggg attggtcgtt tccgttgttt gcaaggtagg
     9121 aagcgaggag ggcaataccc caggcaccac cttcgccggc tgtttccata acggaaatgg
     9181 gtgaattgat ggcagctgcc agtattctct ggcctactcc tttggttttg aagagtcctc
     9241 cgtgaccggt gattctgtct actctgattt tctcttcatt gaaaaggatg tcgttgccga
     9301 ttttgagaac tcccactgaa gcatacagat gggtgcgcat gaagttggca aggttgaact
     9361 tgtcgtttgc cgaacgtaca aacagtggac gtccggctgc cagtcccgtt ataggctcgc
     9421 ctgatatgta gttgtaagag atgaggcctc cgcaatctgc attgcctgtc agggcgtggt
     9481 tatagagttt tccgtagatt tcgtccatat ctacggggat acccatcagt tcctggtatt
     9541 ctttgaaaat attgatccag gcattgaggt cggaagtgca gttgttgcaa tgcaccatag
     9601 ctacgaggct tccgtcgggg gtggttacca tgtcaatcat ttcgtagggc ttggacaatt
     9661 ctttttccaa tacaatcatt gagaaagagg aggtgcctgc cgatacgttt ccagtgcgct
     9721 gctttacggc gttggtggca accatgccgg ttccagcgtc accttcgggt ggacagacgg
     9781 gaattcctgc tttcagatgt cccgatacgt cgaggcgact ggctccttcg ggagtaagga
     9841 agcctgcgtt ttcaccggcc gacaatacct tcggcagaat atcccgaagt ttccagtcgt
     9901 atcctttcgg agcaataagt ttgtcgaact tatccaccat ttcagaagaa tagtttttgg
     9961 tgatgggatc gatggggagc ataccggagg catctcctat gcccagtacc ttttggccgg
    10021 ttatttgcca gtggacaaaa cctgcaaggg tggtcaggta attgatggat ggaacgtgct
    10081 cttcattatc caggatggct tggtagaggt gggagatgct ccaacgcaga gggatgttgt
    10141 agacaaatag ttcggatagg gctgcggcag cctggctggt attagtattt ctccaggtac
    10201 ggaagggtac aaggatttct tctttttcat tgaatgccat atagccgtgc atcatggcac
    10261 tgacaccgat ggctgccagg gtttctatct ctgtatcgta gaggctcttt acattggtac
    10321 gaaggtctgc gtagcaatcc tgcaacccat accagacagc ctcgacgcta tatgtccaca
    10381 gtccgtcgac taactgattc tcccaagtat ggcttccctg ggcgatgggt ttgttttcct
    10441 ggtcaatcaa aaccgccttg attcgtgtgg aaccgagttc tataccaagg atggccttac
    10501 ctgcctcaat ggttgatttt gcatctaatt tcatggtatt aatgataaat tacggattta
    10561 tagtacgatt ataaactacg gattactgat tgcaaactac tagttacgtt tgtggtacgt
    10621 gtaattagta gtccgcaatc ggtaatctgt aatgattatc agcaaagtgc cttgttcagc
    10681 atatagtaga cttcattcat acgcaattct tttttgaact cgctaatggt ggtattttca
    10741 tcgataacca ccatttcgat gccggccatt tcggcaaagt cttcccaata ttccaccgtc
    10801 aagtcgtagg agaagctggt atgatgtgta cctccggcca gaatccaggc tgcagcgccc
    10861 acctcgaggt tgggcattgg aatccacagt gcactggcaa cgggcaactt gggcagaggc
    10921 ttgctcttga tgcattctac tttgttcaca atgaggcgga agcggttgcc caggtctacg
    10981 atggtagcgg ctacaccttc accttgcttg ctggtaaata ccaggcgggc tgtttcgctg
    11041 tcgataccga tgctcagacg gtgcacttcc agtttcggct tctgttcggc aatcagtgga
    11101 cagacttcca acatatgtgc ttgcaggatg gcgctctttt ctccgtcgaa gttcagcgta
    11161 tagtcttcaa ggaaggagca ccccttcggc ataccttgac tcatcaccca agtggtacgg
    11221 tacagtgctg cagttttcca gtcgccttcg gcaccgaagc cgtaaccttc tgccatcagt
    11281 cgctgtgagg ccagtccggg gatttggtca aagtcgccca aatcgttgaa gttggtggtg
    11341 aagcctttgg cacccgtgtc tttcagcacg cggcgaatgg cgatttcggc cttggcggag
    11401 ttccatactt tggtgtaggc ttccgtacgt gcgtcttcca gttcgggagc gtggtcgtag
    11461 agcttgaagt attctgctac gagtgccttc acgtcctcgt cgctgacagc attgtagtat
    11521 gtcatcacat cattgatggg atagtagtcc acatgatagc ccaatacctg ttcggcgctg
    11581 accttgtcac cgtctgtcac agccacgttg ttcatctggt cgccgaagcg gatgatgagc
    11641 atatcctgcg catcagccca tgcggcagct acgcgcatcc atgcggcaat ctggttttgg
    11701 gctttttcgt cctgccagtg gcctactacc actttgcggt tctttcgcat acgtgtcaca
    11761 atgtgtccga actcgcggtc gccgtgagcc gattggttca ggttcataaa atccatgtcc
    11821 atcgtctccc agggaatttc cttgttgaac tgtgtatgga agtgtagtaa tggcttcttc
    11881 agttcctgca aaccgtgaat ccacattttg gcaggagaga aggtgtgcat ccaggtgatg
    11941 accccgatac acttttcgtc gttgttggcg gccttgaagg cagcagttac ttctttggat
    12001 gaattgaccg tacctttata tactaccttt acgggcagtt tcccggaatc attcagacct
    12061 ttcaccattt cattgctatg tgcgtctacc gcgataactg cgtcacctcc gtacaagagc
    12121 tgtgctccgg ttacgaacca tacttcatat tgttcaaatg cgttcataca atttattttt
    12181 atagtttata tttaaagaat gatagttatt tctgtccata ataagcgtta ggaccgtgct
    12241 tgcggctgaa atgcttttct atcagtaacg gattcatggt cagattgggg ttcacggcat
    12301 aggctatact tgccattttt gccacctgct ccatcactac ggcattatgt accgcttcgt
    12361 gtgcgtcttt tccccacgag aaaggaccgt ggttctttac caatactccg ggagtatgta
    12421 ccgggttcag cccctcaaag cgttttacga tgacatttcc cgtttccagt tcatacgctc
    12481 cttccacttc ctccttcgtc atgtctgctg tgcagggtat ggcgtcgtgg aagtaatcgg
    12541 catgtgttgt cccgatattc ggtatgtcac atccggcttg tgcccaggct gtggcgtaag
    12601 tagagtgcgt gtgcaccaca ccgccgattt cggggaatgc tttatagaga accaggtggg
    12661 tcggcgtgtc tgaagagggc tttaaccgtc cttccacgac cttgccgtca agattcacta
    12721 ccaccatatc ctctgctttc atttcatcgt aactcacccc actgggcttg atgactacca
    12781 gaccagattc gcggtcaatg cccgatacat tgccccatgt gaagataacc aatccgtgct
    12841 tcaccagttc aaggttagca tggaatactt tgtctttcag tgcttccagc atattattta
    12901 aattactaat tacaagttgt tgaatattag gttctcagag cttaaatttc ggagctttgc
    12961 ggtatgcctt ctcattaaac tgatataaag cagctccacg tttggacccc gttttgtcta
    13021 ttttgtcagt tttttctata tagtccattt ctgctatgcg ttttcggaag ttccgtttgt
    13081 caatgctctc gccgtatata gcttcgtata agctttgcag ttgtgacagc gtgaacagtt
    13141 taggtagtag attaaagccg attggttcgg tggacgcttt ttgttgcatc aacttccgag
    13201 ctttctccac catttgcgga tgatcaaaga ttagcgctgg cagttcattg atatttaccc
    13261 agaaagcatt gtgttgctgt acggattctt tgtcgtattc gttgatgttg atgagcgcat
    13321 agtaaacaat ggagactacg cgttctcctg ggtcacgatc tatggctccg aaagcttgga
    13381 cttgttccat atatacatct tccagtccgg ttagttcatt caggactcgt ttggctgcat
    13441 catccacgct ttcgtcttcc tgcacgaatc cacccatcag cgaccattcg cccattgccg
    13501 gttcgaagtt acgcttcagc aacagcaggt tcaattctcc ttcattgaaa ccgaaaataa
    13561 tgcagtcgat acctacataa agtttcggat ttgaactata gtaattactc atatcttaat
    13621 ttttgtttaa ggggtatgct gcatggatat atatcatagc aacataccga tttaccagaa
    13681 ataccaataa aaagcagcag taatacccag gatgataagg gtatgaatga tatcccattt
    13741 attccaactc gcacgtgtag ctgctttttg ttcaggagtt gaagttccga ataccagccc
    13801 ttgaatcttt tcagcgcttg gggcagctgt aaacatgctg actgcgataa ccactacgat
    13861 gcagaacaag aacatccatc cgcagaaaaa cagccagttc atatcataga acagatactt
    13921 gaaggtactg cttgacacat ctcctacatt gctgtaatat acttttgccc ccagacgggt
    13981 taaaccgata atcattccgg caatcagtcc ccacataccg ccttgtgcag aggtgcgttt
    14041 ccagcagatc cccaagagga aggctgcggc aatgcctggt gctaatacag attgtacatc
    14101 ttgtaagtag gtgtaaagta catcgcctac actgcgcata atgggaatcc agagtatacc
    14161 caatatcaca a
//
