LOCUS       c00286_gnlPro..        13889 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JKKHPPIG_286.
ACCESSION   c00286_gnlPro..
VERSION     c00286_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:33:05
            Original ID  :: gnl|Prokka|JKKHPPIG_286
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13889
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13889
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6625:13089]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6626..13089
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
     cand_cluster    1..13889
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /kind="single"
                     /product="OD_unknown"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13889
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_unknown"
                     /region_number="1"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /tool="gutsmash"
     CDS             complement(3..74)
                     /locus_tag="ctg286_1"
                     /transl_table=11
                     /translation="MFYSTTFAPAFERERRSKMMKQTF"
     CDS             305..529
                     /locus_tag="ctg286_2"
                     /transl_table=11
                     /translation="MKSCEMHLVLVLSDHVNVGKDPLYRPPKTQKAEEGRTTQTTVYPH
                     VKASGKFPGKNPRAQKAHLYAFKETFLEK"
     CDS             complement(770..2500)
                     /locus_tag="ctg286_3"
                     /transl_table=11
                     /translation="MRRVYSIALLLLVALGLSATMKEVKLKLVETSDIHGNFFPYNFIE
                     QREWGGSLARVYSFVQEERRAYGDNLLLLDNGDILQGQPSAYYYNFMDTVSTHIASAMM
                     NYMGYNAGNMGNHDVEAGHAVFDRWIKQCDFPILGANIIRTSDRETYLKPYEVFERDGV
                     KIVVLGMITPAIPVWLPETLWQGLYFADMEETARKWMKIIQEKEKPDVVVGIFHAGNEA
                     RTMSGQYREDASMEVAQRIPGFDVVMMGHDHRRYCGKVANIEGDSVLLINPASNGRVVG
                     SVDVVLKMEHGKVLDKQVSGVLTDVDKLEPSEEFMEKFAPQYKAVNDFVSEKVGTFTES
                     IATRPAYFGPSAFIDFIHSLQLELTGADVSFAAPLSFDAKIDKGDITISDMFSLYKYEN
                     MLYTMNLTGAEIKGFLEESYAMWTNQMKSPDDHVLLLKERKKGQENYVSFVNFSFNFDS
                     AAGIIYTVDVTKPEGEKITILKMADNRPFDENKTYKVALNSYRGNGGGELLTKGAGIPQ
                     DELKSRIIHSTDKDLRYYMIQYIKEKGVLSPQPLNQWQMIPQDWTRPAAERDCKFLFGE
                     "
     CDS             complement(2519..4945)
                     /locus_tag="ctg286_4"
                     /transl_table=11
                     /translation="MKTYLFLLLFVFQAFSLSSQISLKGYNQEKIDPSLFEGRWKARWI
                     SYPGEAPNVYGVYHFRKSFDLEVVPSRFIVHVSADNRYKLYVNGKLVSLGPARGDIYNW
                     SFETVDLAPYLRKGKNTLASVVWNYAERKPVAQISYDQTGFILQGNTGHEAVVNTDTTW
                     VCLRNKAYAPWTEWQVLGYYVAGPGEELEASAYPWGWEQPDYDDRKWEKAVRGMEGATK
                     GSRDYPGRLLVPSPIPPMDSRIERLAKLRRSEGIECPQGFPYWPKALTIPANTEVRLLL
                     DNDYLTTGYFSLAFSKGKEAEIHIGYSEALYKQEEESTTKSYALNGKGHRDELTDKQFI
                     GYGDKILADGGDNRLFTSLWWRTWRYVELKVKTASEPLVIEDMYGTFSAYPFRNETTFS
                     APGHEELGRMLKIGWRTARLCANETYMDCPYYEQLQYFGDTRIQAMISMYNTSDPYMVK
                     NAIEQGRQSMVAEGITMSRYPSSVHQFISSFSLWWICMGHDYWMYRGDEAYMKTLLPAY
                     RQVLSWYEQWLKPDYSLSYVPHWFFVDWAAGFDYGEPIREKEGNSALQDLMYIMTLEFA
                     AEMEQAIGLPAMADHYRKIATEMRKTIRPKYWDAARNLFADTQDHRSYSQHVNALAILT
                     GVTKGEEAVKVMNQTLADTSLIQCTIYFRYYLNQALKASGLGDQFLDNLQIWRDQMALG
                     LTTWAEMPEPSRSDCHAWGASPNIEFYRILLGIDSDAPGFRKIRIAPSLGKLKEVSGTI
                     PHPLGSVTAAYKLDERGEGTARLVLPEGTTGIFIWDGKEIPLKPGEQVISLSSRH"
     CDS             complement(5067..5855)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg286_5"
                     /sec_met_domain="Fer4_7 (E-value: 4.9e-11, bitscore: 32.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 5.1e-11, bitscore: 31.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1e-05, bitscore: 15.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYSNIHLIYFSPTHTSAKIVYAIAEGMGATSMSESDVTCESLDM
                     EEYIDDELTIIAAPVYGGRVAETAMERFRMFRSAHHAPVVPVVLYGNRDYEDALKELCD
                     LVSEQGFVPVAAGAFIGEHSFSRKGMPIAEGRPDESDLNQATEFGKKIIEELEKVSCVE
                     CLSALEVKGNFPYRVKGPSTPQAPVTDNDLCTQCEYCVDVCPTHAISLADEGMYSDPNL
                     CIKCCACVKECPEGARTFDTPYTAMLHKNFSARREPEIFF"
     CDS             complement(5861..6436)
                     /locus_tag="ctg286_6"
                     /transl_table=11
                     /translation="MRFDENFNVSLSLNPKREMIKVMKKYLLVSLLALLAFVGKAQEDN
                     SDIVKVGDTMPSFTIVSDNGSKLQSASLKGKVILVNFFATWCPPCQKELAAVQQTLWPK
                     YKNNKDFVLLVIGREHSDADLQKYNEKKGFDFPLYPDKDRAIFGAFAKNLIPRGYLVGK
                     DGKIIYTSKGYTDEEFAELMTKIEGALK"
     CDS             complement(6626..7207)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg286_7"
                     /sec_met_domain="POR (E-value: 5.5e-44, bitscore: 140.0,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTDIILSGVGGQGILSIAAVIGEAALKEGLYMKQAEVHGMSQRG
                     GDVQSNLRLSDEPIASDLIPKGHADLIISLEPMESLRYLPYLKKEGWLVTNSRPFVNIP
                     NYPEIEKVNAELDKLPHKVVLDVEEIAKEAGSVRAANIVMLGAAAPFIGIEYDKIEAGI
                     RQIFGRKGEDIVNMNLKALKAGYDLAQSLR"
     CDS             complement(7204..8805)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg286_8"
                     /sec_met_domain="POR_N (E-value: 1.3e-14, bitscore: 44.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-18, bitscore:
                     56.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHLFLGDEAIAQAAIDAGISGVYAYPGTPSTEITEYIQGSPVT
                     KERGIHCRWSANEKTAMEAALGMCYAGKRALCCMKHVGLNVAADCFMNAAMSGINGGMI
                     ILTADDPSMHSSQNEQDNRIYGNFAMIPMFEPSSQQEAYDMVYHGFELSEKLGYPILLR
                     VTTRMAHSRAGVVTSPLKPENRMNCPEDGRQRFILLPALARKRFKSLLASQEAFTEASE
                     NSAYNKYFDAPNKDLGIITTGIAFNYLSENYPDGFEHPVLKISQYPLPRKQVEKIVGEC
                     KEILVLEEGYPVVEEQLKGFLGKGVTVHGRLDGTLQRDGELTPDAVGKALGKEIQSYYA
                     IPEVVEQRPPALCQGCGHRDMYEALNEVIAEYNGTAKVFGDIGCYTLGALPPFRAIDSC
                     IDMGASITMAKGASDAGVFPAISVIGDSTFTHSGMTGLLDCVNENTNITIVISDNETTA
                     MTGGQDSAGTGRLESICAGIGVDPAHIRVMVPLKKNFEEMKSIIREEIEYKGVSVLIPR
                     RECIQTLTRKKKASKK"
     CDS             complement(8911..9960)
                     /locus_tag="ctg286_9"
                     /transl_table=11
                     /translation="MDLNKQILSRRPIIIALIAILVVLIGGGGFWVYRLAWAPNFKPDK
                     TVYVYIDDKKDFNDLCRQLRDSANCLRIGSFKQLSGLLKYPASMRTGRYAVKPGMSNLT
                     LLNDLRRGHQVAARVTFNNIRFKEDLAERISDQLMFGKENLLRLLNDSVYCDSLGFTPE
                     TIHALFIPNTYEIYWNISADKFIRRMKREYDAFWTPERLKKAEEIGLTPVEVSILASIV
                     EEETAASDEYPIVAGLYINRLHAGIPLQADPTVKFAVGDFSLQRILFEHLEIDSPYNTY
                     KYAGLPPGPLRIPTIKGLNSVLNHTKHKYLYMCAKEDFSGRHNFAVTLAEHNRNANRYR
                     AELNRRRIR"
     CDS             10326..10940
                     /locus_tag="ctg286_10"
                     /transl_table=11
                     /translation="MTIAFIRTYNNKQNSEVQEAVIREFAESQKIEIGKWAKEVGNSPR
                     ANRRLESIVKSLSPGDEILVSDISRVSRKMIEIIHIILLCIERKVTLRSVSDGYVFEDN
                     IDSKTLAFTFGLVSEIERKLVSIRTKEALALIRSKGVVLGRPKGSQQMGRLEPYKEQIE
                     KDLKDPSLTYAQIAEKYNVSLSSFKRFLKEYLPDKKKKKKK"
     CDS             complement(11029..13089)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: CoA_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: Succ_CoA_lig"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg286_11"
                     /sec_met_domain="Succ_CoA_lig (E-value: 5.3e-37, bitscore:
                     116.4, seeds: 149, tool: rule-based-clusters)"
                     /sec_met_domain="CoA_binding_2 (E-value: 4.6e-22, bitscore:
                     68.5, seeds: 225, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINRELINPQSIVVVGGSNNVHKPGGRIVRNLLDGKYKGELCVVN
                     AKETDVQGVKSYPSVHDIPETELAIISIPSKSCPEVMEVLARQKGVKAFIVISAGFGEE
                     THEGGILEQQMLDVVNEAGASLIGPNCIGLMNMNYHGVFTQPIPEFHPDGVDFISSSGG
                     TALFIIESALTKGLRFSSVWSVGNSKQNGVEDILEYMDRNFDPVLDSKIKMLYIEQIKQ
                     PDKLLYHASSLIRKGCKIAAIKAGSTESGKRAASSHTGAIASSDSAVEALFRKAGIVRC
                     FSREELTTVASIFTLKDVKGKNCAIVTHAGGPAVMLADALSKGRLNVPSLEGPIADELK
                     SKLYPGAAVGNPIDIIGTGTPEHLATAIDFCENRFDNVDLMMVIFGSPGLVKLYDTYEV
                     LHKKMEECKKPIFPILPSIVTAGPEVKSFVKKGHVNFSDEVTLGTALSRVINTPKPMST
                     DIQLYGVDVPEVRRIIDRLPGSGYLNPEEVRTLLRAANIPLVEEYASDDRDALLAFAKK
                     VKYPVVAKVVGPVHKSDIGGVALNIRGEEHLLFEYERMMRLPGVTGIMVQPMLKGQELF
                     LGAKYEDRFGHVVLCGLGGIFVEVLKDVSYGLAPLSYDETYSMIRSLRGYPIIKGTRGQ
                     KGIDEQQYADIIVRLSTLLRFASEIKEMDINPLVATDRGLFAVDARIRIEK"
     CDS             complement(13169..13888)
                     /locus_tag="ctg286_12"
                     /transl_table=11
                     /translation="HHHDHTHEHSHGHEHHHHPDEGIVINLEQDILQRNNLLAERNRGY
                     FEAKNLFCLNLMSSPGSGKTTLLEETIRRLKAKRPIYVIEGDQQTSNDADRIAALEIPV
                     FQVNTGTGCHLEADMVNHAVKHLNPKEGAILFIENVGNLVCPAMFDLGESKKVVIVSTT
                     EGDDKPLKYPHIFQEADICVINKIDLAPYLNTKVEVLRENALKVNHHLQIFEVSATKGD
                     GMDAWCDWLQTESAKCK"
ORIGIN
        1 ctaaaagttt gtttcatcat tttggaccgg cgttctctct cgaatgcggg tgcaaaagta
       61 gtgctataaa acataacctc caaacttttc cggtattatt tttcaagttt ttttcacgag
      121 ggggatcgcg tacattaata atacgtcgat atccattctc ggctcacatg gcccaccacg
      181 tggcctcacg tgtcaccacg tgcacttaaa acaagtgctc cacgagtaca tttgcacgta
      241 tgaaaacgac aaaaacgatc ttggccccga taggaaatca cacagaaaaa acggctttta
      301 gctcatgaaa tcatgcgaaa tgcacttggt tttagtgctt tcggatcacg taaacgtggg
      361 taaggaccca ttatatcgcc ccccaaagac ccaaaaagcc gaagagggaa gaaccacaca
      421 aacaactgta tatccacatg ttaaggcatc aggaaaattc cccggcaaaa atcctagggc
      481 gcaaaaggcg catctttacg ctttcaaaga aacattttta gaaaaataat atttacatca
      541 ctctacagac aagaggggta taaacgttat ttacagaaaa agttttagaa acatacgtaa
      601 agatgcgccc cttgcgccct aacctatcag caacatccct aatacgggat acaaaaaagt
      661 caatgggaca cggccgtaaa gtcattgaga aaccatctct attccattga ctttaccacc
      721 gtttcccatt gagatactat cgcaaaccag acacttcaag gacggaaact cattccccga
      781 aaagaaactt acaatcccgt tcggccgccg gtctcgtcca atcctgcggg atcatttgcc
      841 attggtttaa aggttgtggg ctaagtacgc ccttttcctt tatatattga atcatataat
      901 aacggaggtc tttatcggtc gaatgaatga tacgactctt taactcgtct tggggaatac
      961 cggccccttt cgtcaataac tcacctcctc cattacctcg gtaagagttg agagctactt
     1021 tatacgtttt attctcgtcg aagggcctgt tatccgccat tttcaagatc gtaatcttct
     1081 caccctctgg tttcgttacg tccacggtgt aaatgatacc agctgcggag tcaaagttaa
     1141 aactgaagtt gacgaatgag acataattct cctgtccttt ctttctctct ttcaataata
     1201 agacatgatc gtccggagat ttcatctggt tggtccacat agcgtatgat tcctccaaga
     1261 aacctttgat ctcggctccc gtcaaattca tcgtataaag catattctca tatttgtaaa
     1321 gactgaacat atcgctgatc gtgatatccc ctttatctat ttttgcgtca aaggataacg
     1381 gggcggcaaa agagacgtcc gcaccagtca actccaattg taaagagtga ataaaatcaa
     1441 taaaagcgga tggcccaaag taagcgggac gggtcgcgat actctccgta aaagttccca
     1501 ccttctcgga gacaaaatca ttcaccgctt tgtattgcgg agcgaatttc tccataaact
     1561 cctcgctagg ctccaactta tccacatccg tcaaaacacc cgatacttgt ttatccaaaa
     1621 cctttccatg ctccatcttt aacacgacat caacggaacc gactacacgc ccattacttg
     1681 ccggatttat cagtaacacg gaatctccct cgatattcgc caccttacca caataccggc
     1741 gatgatcatg ccccatcata accacatcga agcccggaat gcgctgggca acctccatcg
     1801 acgcatcctc acggtactgg ccggacatgg tacgagcctc atttcccgca tgaaagatac
     1861 ctaccacaac atccggtttc tccttctcct gaatgatctt catccattta cgggccgtct
     1921 cttccatatc ggcgaaataa agaccttgcc acagagtctc cggcaaccat acaggaatgg
     1981 caggagtaat catccccagt acaacgatct tcacaccgtc acgctcaaat acctcataag
     2041 gctttaaata ggtctcccgg tcggaggtac ggataatatt ggcacccaag attgggaaat
     2101 cacattgttt gatccaacga tcgaaaacgg catggccagc ctctacatca tggttaccca
     2161 tatttcccgc attgtacccc atataattca tcatggcgga agctatatgc gtagagaccg
     2221 tatccatgaa attgtaataa tacgccgaag gttgtccttg caagatatcg ccattatcca
     2281 atagcaaaag gttatcgcca tacgcccggc gttcttcttg cacgaacgaa tatacccgtg
     2341 ccagacttcc tccccactcc cgctgctcga taaaattata cgggaagaag tttccatgga
     2401 tatcactggt ttccactaat ttcaacttta cttccttcat tgtcgccgac agaccgagag
     2461 cgaccagcag caataaggca attgaataaa ctcgtctcat atcaggattt tagatagatt
     2521 aatgacgcga agataacgaa ataacctgtt cgcccggttt caacgggatt tcttttccat
     2581 cccagataaa tatacccgta gtaccttccg gcaagaccag acgggcggtt ccctcacctc
     2641 tctcatccaa tttataagcg gcggtcacgc ttccaagcgg atgtgggatc gtaccggaaa
     2701 cctccttcag ttttcccaaa gacggagcga tccgtatctt cctaaatccg ggagcatcgc
     2761 tatctatccc caacaagatc cggtaaaact cgatattcgg actggctccc caagcatggc
     2821 aatcagaacg ggatggctcc ggcatctctg cccatgtggt caatcccaac gccatctgat
     2881 cccgccatat ttgtaagtta tccaagaact gatcccctaa accggaagct ttcaacgctt
     2941 gattcaagta ataacggaaa tagatcgtac actggatcaa gctcgtatcc gccaaggttt
     3001 ggttcatcac ctttacggcc tcctcccctt tcgtaacccc agtcaagatc gccaaggcgt
     3061 tcacatgctg ggaatagctg cgatgatcct gcgtatcggc gaatagatta cgggcagcgt
     3121 cccaatattt cgggcggatc gtcttacgca tctcggtagc gatcttccgg taatgatccg
     3181 ccatggcagg gaggccgatc gcttgttcca tctccgccgc aaactccaag gtcattatat
     3241 acatcaaatc ttggagcgcc gagtttccct ctttctcccg tatcggctcg ccataatcaa
     3301 aaccggccgc ccaatccacg aagaaccaat gaggaacgta cgacaaacta taatccggct
     3361 tcaaccattg ctcgtaccac gacaaaacct gacggtaagc gggaagcaag gtcttcatgt
     3421 atgcctcatc cccacggtac atccaataat cgtgccccat acaaatccac cagagagaga
     3481 acgaggatat aaactgatgt acgctagacg gatatcggct catcgtaatc ccttccgcca
     3541 ccatggactg ccgtccttgc tctatggcat tcttcaccat ataagggtct gatgtattat
     3601 acatggaaat cattgcctgt atgcgtgtat ccccgaaata ttgcagttgc tcgtaatacg
     3661 ggcagtccat atacgtctca ttggcgcaca gacgggcggt acgccatcct atcttgagca
     3721 tacggcccag ctcctcatgt cccggagcgg agaaagtggt ctcgttacgg aaaggatagg
     3781 cggagaaagt cccatacata tcctcaatca ccaaaggctc ggaagccgtc ttcactttca
     3841 actccacata tctccatgta cgccaccaca gggacgtgaa gagacgatta tctcccccat
     3901 cagccagtat cttatccccg tacccgataa actgcttatc cgtcaactcg tcccgatgtc
     3961 ccttgccatt caacgcatac gatttagtgg tcgattcctc ttcttgctta tagagggctt
     4021 ccgaataacc gatatggatc tcggcctcct ttcctttgct gaaggctaag gagaaataac
     4081 ccgtcgtcaa gtaatcatta tccagaagca agcggacctc cgtattcgcc gggatcgtca
     4141 aagcttttgg ccagtaagga aatccttgcg ggcattcgat cccttccgac cggcggagct
     4201 tggccagacg ctcgatccgg ctgtccatcg gaggtatcgg gctaggaacc agcaaccgtc
     4261 ccgggtaatc tctcgatcct tttgtggcac cctccatgcc ccgtacggcc ttctcccatt
     4321 tcctgtcgtc gtaatccggt tgttcccagc cccaaggata agcggaggct tccagttcct
     4381 cacccgggcc agccacgtaa taccccaata cctgccattc ggtccaagga gcatacgcct
     4441 tattacgcag gcagacccaa gtggtatccg tatttaccac cgcctcatgc cccgtattgc
     4501 cttgcaggat aaaacccgtc tgatcgtaac tgatctgggc gacaggtttc cgctcggcat
     4561 aattccagac aacggaggcc agcgtattct tccctttcct cagataagga gccagatcca
     4621 ccgtctcgaa actccagtta tagatatccc cacgggccgg gcccaaggat accaatttcc
     4681 cgtttacata taatttataa cggttatcgg cggaaacatg gacgataaac cgggaaggaa
     4741 ccacctccag atcgaacgat ttacgaaaat gatagacccc atatacattc ggggcctcac
     4801 ccgggtagga gatccaacgg gctttccatc gtccctcgaa aagagaagga tcgatcttct
     4861 cctgattata ccctttcagg ctaatctggg aggaaaggga gaaggcttga aacacaaaaa
     4921 gcaaaaggaa taaataggtt ttcatacaaa cacggtatta tttgagatta acgatccgaa
     4981 caaaggtaca aaaaaagaga aagcgccaaa agaacttttg ccttttgacg ctttccctca
     5041 caatataccg gatgcccggt cctccattag aagaatatct ccggctccct gcgtgcgcta
     5101 aagttcttat ggagcatcgc cgtgtaagga gtatcgaaag tacgtgcgcc ctcgggacac
     5161 tctttcacgc aggcgcaaca tttgatacat aggttcgggt cgctatacat accctcgtct
     5221 gccaaggata tcgcatgtgt aggacacaca tccacgcaat actcacattg cgtacataaa
     5281 tcattatccg taacaggagc ttgaggagtg gaagggcctt tcacccgata cgggaaatta
     5341 cctttcacct ccaaggcgga caagcattcc acgcaggaaa ccttctccag ctcctcgata
     5401 atctttttcc cgaattccgt agcctgatta agatccgact cgtccggacg cccctcggca
     5461 atgggcatcc ccttgcggct gaaagaatgc tcgccgataa acgctccggc agccacaggt
     5521 acgaacccct gctccgacac taaatcacag agctctttca aggcatcctc ataatcccgg
     5581 ttcccataca gtaccacggg gactaccggc gcatggtggg cagaacggaa catgcgaaaa
     5641 cgttccatgg cagtctccgc cacacggcca ccgtatacag gagcggctat aatcgtcagc
     5701 tcatcatcaa tatactcttc catatccaga ctctcacaag tgacatcaga ctcggacatc
     5761 gaagtggcac ccattccttc cgctatcgcg taaacgatct tggcggacgt gtgtgtcgga
     5821 gaaaaataaa ttaaatgtat gttactatat ttcatgattc ttattttaac gcaccctcta
     5881 ttttagtcat taactcagca aattcctcat cggtatagcc tttgctcgta taaatgatct
     5941 tcccgtcttt tccgaccaaa tagccacgag ggatcaagtt cttggcgaaa gcgccgaaaa
     6001 tagcccggtc cttatcggga tacaaaggaa aatcgaagcc ttttttctcg ttatatttct
     6061 gtagatcggc atcggaatgc tcacgcccga tcaccaagag aacgaagtcc ttgttgttct
     6121 tgtatttcgg ccagagggtt tgttggacag cggccaattc tttttggcag ggaggacacc
     6181 aagtggcgaa gaaattcacg aggatcactt ttccctttaa cgaagcggac tgcaacttac
     6241 tcccgttgtc ggaaacaatc gtaaatgacg gcatggtatc accgaccttc acgatatcgg
     6301 aattatcctc ctgagctttg cctacgaaag ccaataacgc tagtaaacta accaataaat
     6361 acttcttcat aaccttaatc atttctcgtt taggattcag cgacaaagat acattaaaat
     6421 tctcatcaaa ccgcataatt ctaaggctta cgaaagttct acgatgccgt acctacccct
     6481 cgacagtgcc tacggagttt ttttgatgcc gtacctaccc ctcgacagct cttctaaaag
     6541 ttctaggggg ttagatgtta aaaaaaacgt acgtgaaacc cggagatgtc acgtacgctg
     6601 ataccatgca aacccggaga aagatttacc gcaaactttg cgctaagtca taaccggctt
     6661 tcaatgcctt taggttcata ttaactatat cctcgccctt acgaccgaat atctgacgga
     6721 ttcccgcctc gatcttatca tactcgatcc cgataaatgg ggcagctgca cccaacatca
     6781 cgatattggc ggcacggaca gaacccgctt ccttggcgat ctcctccacg tccaatacga
     6841 ccttgtgagg gagcttgtcc aactcggcgt tcactttctc gatctccgga tagttcggga
     6901 tgttcacgaa cggacgggag ttcgtcacca gccaaccctc tttcttcagg taaggcagat
     6961 aacgcaagct ctccatcggt tccaaggaga tgatcaaatc ggcgtggccc ttcgggatca
     7021 agtccgaggc gatcggctcg tcggaaagac gcaggttaga ctgcacgtct ccaccccgtt
     7081 gactcatacc gtgtacttcc gcttgcttca tatacagacc ttcttttaag gcggcttctc
     7141 caataacggc ggcgatagaa aggataccct gtcctcctac acctgatagt ataatatctg
     7201 ttttcatttc ttgcttgctt ttttctttct ggttaatgtc tggatacact cacggcgggg
     7261 gatcaatacg gatacgccct tgtactcgat ttcctcacgg atgatagact tcatctcctc
     7321 gaagttcttt tttaaaggaa ccatcacacg gatgtgagcc ggatccacac cgataccggc
     7381 gcagatagac tccagacgtc ctgttccggc ggaatcctgc cctccggtca tggccgtcgt
     7441 ctcattatcg gagataacga tggtgatatt cgtgttctcg ttcacgcaat ccagcaaacc
     7501 agtcataccg gaatgggtaa acgtagaatc gccgatcacg gagatagccg ggaatacacc
     7561 cgcgtcggaa gcgcccttcg ccatcgtgat ggaggcgccc atatcgatac aagaatcgat
     7621 cgcccggaaa ggaggcaaag ctcccaaggt ataacagccg atatcgccaa acaccttagc
     7681 cgtaccgtta tactcggcga tcacctcgtt caaggcctca tacatatccc ggtgtccaca
     7741 accttggcac aaggcgggcg gacgttgctc aaccacctcg gggatcgcgt aatagctctg
     7801 gatctcctta cccaaggctt tgcctaccgc gtctggcgta agctcgccgt cacgctgaag
     7861 cgtaccgtcc aaacggccat gaaccgtcac tcccttcccc aagaaaccct tcaattgctc
     7921 ctcgacaacc ggatacccct cttccagcac caagatctcc ttacactcgc caacgatctt
     7981 ctccacttgc tttctcggaa gcggatactg ggagatcttc aatacgggat gctcgaaacc
     8041 gtccggataa ttctcggaaa gataattgaa agcgataccc gtcgtgatga tacccaagtc
     8101 tttattcggg gcatcgaaat acttattata cgcggaattc tcggaagctt ccgtgaaagc
     8161 ctcttgagac gccagcaaac tcttgaaacg tttacgggcc aatgccggga gtaagataaa
     8221 acgttgacga ccgtcttccg gacaattcat ccggttctcc ggcttcaacg ggctggttac
     8281 gacaccggca cgagaatgcg ccatacgggt cgttacacgc agcaagatag gataccctaa
     8341 tttctcggat aactcgaatc catgatatac catatcataa gcctcttgct ggctggatgg
     8401 ctcaaacatc gggatcatgg cgaaattgcc ataaatacgg ttgtcttgct cattctggga
     8461 agagtgcatg gatgggtcgt cggccgtaag gatgatcata cctccgttga taccgctcat
     8521 agcggcgttc ataaagcaat cggcggctac attcaaaccc acgtgcttca tgcagcaaag
     8581 cgcacgttta ccggcatagc acatacccaa agcggcttcc atggcggttt tctcattcgc
     8641 gctccagcga caatggatac ctctttcctt cgttaccgga gaaccttgga tatattctgt
     8701 gatttcagta gaaggggttc ccgggtatgc gtataccccg gagattccag cgtctatagc
     8761 ggcttgcgct atggcctcgt cccccaaaaa taaatgtttt tccatgtgta tctgttttct
     8821 taaatattga ctattcacac tatttagccg ccaaaggtaa tgaaaaatgt tcaatttaga
     8881 atgagagact tatgatttat actagatcca ttaccgtatc cggcgcctat tcaactccgc
     8941 ccgataccgg ttggcattac ggttatgctc cgccaacgtc acggcgaaat tatgccgtcc
     9001 cgagaaatcc tccttagcgc acatgtataa gtatttatgt ttcgtatgat tcaatacgct
     9061 attcaagccc ttgatagtag gaatccgtag aggaccggga ggcaggcccg catatttata
     9121 ggtattatag ggagaatcta tttccaaatg ctcaaataag atacgttgca aagaaaaatc
     9181 ccccaccgca aactttacgg tagggtctgc ctgtaaagga ataccagcat gaaggcggtt
     9241 gatataaagc cccgccacga ttggatattc gtccgatgcc gccgtctcct cttctacgat
     9301 agaagccaag atagatacct cgactggagt aagcccgatc tcctctgcct ttttcaatcg
     9361 ttccggtgtc cagaaagcgt catattcacg cttcatgcga cgtataaatt tatccgcgga
     9421 tatattccaa taaatctcat aggtattagg aatgaaaagg gcatggatcg tttccggggt
     9481 aaaacctaaa gagtcgcaat acacagaatc attcaataga cgcaggagat tttccttccc
     9541 gaacatcaat tgatcactta tacgttccgc caaatcttcc ttgaaacgga tattattaaa
     9601 agtaacccgg gccgctactt gatgtcctct ccgcaagtca ttcaataagg ttaaattact
     9661 catgccgggc ttcacggcgt atcgaccggt acgcatggac gcaggatact tcaacaatcc
     9721 actcaattgc ttaaagctac cgatacggag acagttcgcc gaatccctca actgccggca
     9781 aagatcatta aaatcctttt tatcatctat atagacatag accgtcttat ccggcttaaa
     9841 attcggagcc caagccaaac ggtacaccca aaagcctcca ccgcctatca aaacaacgag
     9901 aatcgctatc aaggcgataa ttattgggcg cctcgataaa atttgtttgt tcaaatccat
     9961 gaataatcta ttgaatatca gaataaggca caaaagtagt atcttttttc gaaaaaaatg
    10021 atgtgcagag ccttgtttat ttaaaattat agttctacct ttgcatcgca attctaagga
    10081 agaagcacag aacacacaag gaagtgtggg tgagtggctg aaaccaccag tttgctaaac
    10141 tgacgtactc gtaagggtac cgggggttcg aatccccccg cttccgcaaa gagccaacta
    10201 ataaatttat tagttggttt ttttgttttt aagccaaccg aattaaagtg tttcatatat
    10261 ttgtcatatt tgaacttatc gtaagtcgat ctgttattaa aaggagataa ttaaatatat
    10321 acattatgac aattgctttt atccgaacat ataataataa gcaaaactcc gaggtccaag
    10381 aagctgtgat ccgggaattt gccgaatctc agaagataga gatcgggaag tgggctaaag
    10441 aggtgggaaa tagtcctcgt gcgaaccgca gactggaaag tattgtcaaa tctttaagtc
    10501 ccggggatga gatacttgtg tccgatatat cccgtgtgag ccgtaagatg atcgagatca
    10561 tccatatcat tttgctttgt atagagcgaa aggtaacgct tcgtagcgta agcgacggat
    10621 atgtgttcga ggataatatc gacagtaaga ctttggcctt taccttcggt ctggtctccg
    10681 agatcgagcg aaagctggtc tctatccgta cgaaggaagc ccttgccttg atcagaagta
    10741 aaggtgtggt gctgggccgt ccgaaaggta gtcaacaaat gggacgcttg gagccttata
    10801 aggaacaaat cgagaaagac ttgaaagacc cgagcttgac ttacgcccag atagcggaga
    10861 aatacaatgt atcgctaagt agcttcaaac gcttcctgaa agagtatctt cccgataaga
    10921 aaaagaagaa gaagaaataa tgattcaatg tgccaatatg ccaatgaaat accagaagtg
    10981 gataatttag atattagcat attcgcatat tggcacattg aatcattatt atttctctat
    11041 acggatacgg gcgtctacag cgaacaagcc tctatccgta gccaccaacg gatttatatc
    11101 catttccttt atctcgctgg caaaacgcaa taaggtagag aggcgaacga taatgtccgc
    11161 atattgttgc tcgtcgatgc ccttttgccc acgcgtacct ttaatgatcg gataccctct
    11221 caaggaacga atcattgaat aagtctcatc atatgataac ggtgccaaac cataagacac
    11281 atccttcaat acctccacga agattccacc caacccgcaa agtaccacat ggccgaaacg
    11341 atcctcatat ttagctccca agaataattc ctgtcctttc aacatcggtt gtaccatgat
    11401 gcccgtaaca cccggcagac gcatcatacg ttcatactcg aacaataaat gctcttctcc
    11461 acggatattc aaggccacac caccgatatc gctcttatgc acaggcccca caaccttggc
    11521 taccaccgga tatttcacct tcttggcaaa agccagcaac gcatccctat catccgaagc
    11581 atattcctcc actaacggga tattagcggc acgcaacaat gtacgcactt cctccggatt
    11641 taaataaccg ctacccggca accggtctat gatacgacga acttccggta catccacgcc
    11701 atatagctgg atatccgtgc tcatcggttt cggcgtattg atcacccgtg aaagggcagt
    11761 acccaatgtc acctcgtccg agaagttcac atggcctttc ttgacaaagc tcttcacttc
    11821 cggtccggcc gttacgatag acggtaatat cgggaagatc ggcttcttgc actcttccat
    11881 ctttttatga agtacctcgt aggtatcata aagttttacc aaaccgggac taccgaagat
    11941 gaccatcatc aaatccacat tatcgaaacg attctcacag aaatcgatgg ctgtagccaa
    12001 atgttccggt gtccccgtac cgataatatc aatcggatta ccgacagcgg cacccggata
    12061 cagtttggat ttcaactcat cagcgatagg gccttccaaa ctaggaacat tcaaacgccc
    12121 cttggataaa gcgtccgcca gcattaccgc aggccctccg gcatgtgtca cgatcgcaca
    12181 attcttccct ttcacgtctt tcaaggtaaa gatactcgcc acggtagtca attcctcacg
    12241 gctaaaacaa cgcacgatac ccgccttacg gaacaaagcc tccacagcag agtccgaact
    12301 agcgatagcg cccgtatgcg aagaggcagc tcgctttccc gactccgtac ttcccgcctt
    12361 gatagcggcg atcttgcatc ccttacgtat caaggaagac gcatgataca acaatttatc
    12421 cggttgcttg atttgctcga tatacaacat cttgatcttg gaatccaata ccggatcaaa
    12481 gttccgatcc atatattcaa ggatatcctc tactccattc tgcttggagt ttccaaccga
    12541 ccaaacagaa gagaaacgca gcccttttgt cagcgccgac tcgataatga acaaggccgt
    12601 accgccggag ctagagatga aatccacgcc atcgggatgg aattccggta tcggttgcgt
    12661 aaacacgcca tgataattca tattcatcaa cccgatacag ttcgggccga tcaaggaagc
    12721 tcccgcctca ttcacgacat ccagcatctg ttgttccaag ataccgcctt cgtgtgtctc
    12781 ctcgccgaaa ccggctgaga tcacgataaa agcttttacc cccttttgcc gggccagcac
    12841 ttccatcacc tcggggcacg atttactcgg aatcgagatg atcgccaact ccgtctccgg
    12901 gatatcatgt acagaaggat aagacttgac gccttgcacg tctgtctcct tggcgtttac
    12961 cacacataat tctcctttat attttccatc caacaggttt cgcacgatac gaccgcccgg
    13021 tttatgtacg ttgttggaac ctcccaccac tacgatgctt tgaggattaa tcaattctcg
    13081 gttaatcata acattttgat tagttagatt caatgaatgg gagcaaatat agtttttttc
    13141 tccatttatt cattaaaacc cgtggtattt atttacactt tgcactctct gtctgcaacc
    13201 agtcacacca tgcatccatc ccgtctcctt tcgtggcgga tacctcgaat atctggagat
    13261 ggtgatttac cttcaaggcg ttttcccgaa gcacttccac ttttgtattc agataaggag
    13321 ccagatcaat cttgttgatt acgcagatat ctgcctcctg aaagatatgt gggtatttca
    13381 acggtttatc atctccctcc gtcgtactca cgataacgac tttcttggac tctccgagat
    13441 cgaacatggc cggacagacc agattgccga cattctctat aaaaaggatc gctccctcct
    13501 tcggattcag atgcttaacg gcatgattga ccatgtcggc ttccaaatga cagccggtac
    13561 cggtatttac ctgaaacacg ggaatctcca acgccgctat acggtcggca tcgtttgagg
    13621 tttgttgatc gccttctatc acatagatcg gtcgcttcgc tttcaaacgg cggatcgtct
    13681 cttccagcaa ggttgtctta ccggatccgg gcgaactcat caagttcagg cagaacaggt
    13741 tcttagcctc gaaatatccc cggtttcgct ccgccaataa gttgttacgt tgaagtatat
    13801 cttgttccag attaattacg atcccttcat caggatggtg atgatgttca tggccatgag
    13861 aatgctcatg cgtatgatcg tgatggtga
//
