LOCUS       gnlProkkaCAIBLCGG_59   15188 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CAIBLCGG_59.
ACCESSION   gnlProkkaCAIBLCGG_59
VERSION     gnlProkkaCAIBLCGG_59
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:59:55
            Original ID  :: gnl|Prokka|CAIBLCGG_59
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15188
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..225)
                     /locus_tag="ctg59_1"
                     /transl_table=11
                     /translation="MNGLWYNDFVLVIGAGGNSSDVSYRVHRDGEICIIKILLTNAQKP
                     VIVKNRFGVLLDRQALTGHKCYFLMFMGVS"
     protocluster    1..15188
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9642:9915]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9643..9915
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15188
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15188
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(314..1234)
                     /locus_tag="ctg59_2"
                     /transl_table=11
                     /translation="MNKKKALFLGVLCIVLIIVACFFALNRKDKINETSAEKVEQEKSA
                     TEEAKKEVKKETKRTEVKKKKNKAKKEEKTDTEDASQQSSDDTDEIYVGPLVDKDSGAQ
                     ETGPKESQAEPVEFPYDVPGTGITVQNISSYSGIYVEDGSDQEISNVSAMQMYNSGSNA
                     VEYVSVSVKCNGEQLEFEASDIPAGASVMVQEKNKKAYQSGTYTECVGTAAKVDGFGMS
                     EDKVQVTPNDDNTFTVTNLTEETIPCVRIFYKLYMEDKGIYVGGITYNVKVTELEAETS
                     QTVSPSHYAQGYSRLMMVRTYDTTE"
     CDS             complement(1227..2375)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_3"
                     /sec_met_domain="PF04055 (E-value: 9.5e-23, bitscore: 71.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.9e-08, bitscore: 22.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMSSVSAPITKYLMAKAVRQKIPLSGIFELTPLCNMNCRMCYVR
                     MNREEQEKIAPLGTVEQWLEVGKEARDSGMLYLLLTGGEPFLRKDFREIYQGLYDLGII
                     IEINSNGTLIDEQTVAWLREVPPQRINITLYGASDVTYGRLCRNPKGFTQVSRAIRLLK
                     EARINVRLNCSVTPYNADDLEDIFAFGRREYIPVRAASYMYPPVRRDASSVGVNDRFSP
                     EEAAYYDARIKAYSLGDEKFLEWADRNENILPELNDDICGEMKAEGVRCHAGRSSFWVT
                     WNGCMVPCGMFRGEEEHNVFQEGFTKNWKRVLEETARIRLAPECGACAKRDICKSCAAM
                     EITENGKFGNIPEYRCQMVKTMPDAVRKVKQEILEERRKCNE"
     CDS             complement(2366..3250)
                     /locus_tag="ctg59_4"
                     /transl_table=11
                     /translation="MLYLYTIAEICIFVESSFPIKIEEDSEDFLKSVDIKELKKLEDNQ
                     VYVRFSPVDKITVIESGGIKVENRYEVKEGEYKKIYVYSYGDFPYACLENKNNRIICRY
                     IKKYVHMLNCSRKLFNILGMESIFLLNKTFILHASFIRWKGKGILFSAPSGYGKSTQAS
                     LWEKYEKAEILNGDRAALRMKDDEWHAYGMPYAGTSGIYRNESAPVKIVFVIRKAGKNS
                     IRKLPLPEALRYLYPEVTVHRWDKEFLNTIMDYLICFATQVPIYMLECLPEKSAVELAK
                     TVLEYQKEDEEWK"
     CDS             complement(3397..3663)
                     /locus_tag="ctg59_5"
                     /transl_table=11
                     /translation="MDGFREEKEMKKVYKKPVLYIEKFTVDKNFANSCGAEPGTSEFGS
                     EFTCSWNAFFHDGVLSCELDPKDQGTEADCYNGLWNSASPFAS"
     CDS             complement(3650..7078)
                     /locus_tag="ctg59_6"
                     /transl_table=11
                     /translation="MQSKTKKAFRNVLAFLTVLTMMLGMLPTTLLAANTDDSGTAGESG
                     MHLSKTARLEDDGTYTINLEAYATGKTTTTITKEAVPLDIVLVLDQSGSMSDDMGYTYT
                     LEDKTSYSYDDINSSARYYLDTDGNYYKVQREKNGIGSWRKYYLFYKKDGTSYYLNGDE
                     VTTNKRECNYTGSGDTIWASQLYSRTITTKLDALKDAVSNFVGVVKEKATTDKVNHRIA
                     MVGFASESDYGNNTEILSVDGSNSGSVGVSYNSDKYADAKQNAFQDTSTDAGNTMLNNA
                     INALDANGATRADLGMTMAKDILDANSLGDDSKRKQLVIMFTDGKPTSWDTFDENIAND
                     AIGTSKGLKDQGTTVYTIGVFNGADPSSTSDVNKYMNYVSTNYPSAEKLDNSGKGGNNG
                     YYLAATSADGLNKIFTSISNTITTPSTTVALNKNAVMKDILSDDFTLPEGYNAGDKITV
                     STVPGSTEDGNSISWGTESKSKDIKATIDDNTINVTDFDYSNEYIAPRHNGEKLVVTIK
                     GVIPKDSAATGEKVYTNNEASGIYAEGAPEPAAKFPRPQVVLTNKAYVLDYAKPVTLSP
                     SDWKMSSDNMAITGSIGEKDASYAPKYGSLKNLVYSPKTTNWDGYDKFYAFGETTDNDI
                     KEINGNDNLWSRVSVLPANNVYYEDDFETNNEAGTVGIEYTGNWTTDTSNLGSANTESV
                     NTDIHGGWTNTDLSNDTKYSDGSAHMADADNKGDTGKAATATFTFSGTGVDIYSRTNGT
                     VGKVSAILSSITTDGKKVVKAVSMDNKSASGDYYQIPTLSFGPLDYGKYEVKLVVVAAG
                     KKGTEDRRGTYYLDGIRVYNPIQNKETDAVVSEAYGTDMLNATFKEVRDILLDTGTTTG
                     ELANGAIVFLDRTTDDNSKTSNKVAEFRDYGPKNEVYLAKGQKIAFKVIDSKASYYVGL
                     KAPEGKTTVRLTNDKNASSTEIGHSTDLYYKITPVSEGDYAGCIVIENTGDNLLAITKI
                     YYNNKLGGIEGISDTESAQTVTYSATSADAFDDGSQFTDASDGDMPEADNTDLFAAEAE
                     EVPEAEESVSVLENPLVLKLVEYANVFDTLSEVPYEDKTVEGTPDSGQDENTEVTEPDD
                     GNVDITNPEPNEDQKPIDKIHSWLNKLFQGFNGWL"
     CDS             complement(7233..9674)
                     /locus_tag="ctg59_7"
                     /transl_table=11
                     /translation="MRGEYLNRMFSSKTHYEPFNNQQYYIDKTEFLEKGMATFPSLYIE
                     GAAASGKTTVVRMFLSRYPDMEYFVFWMDTEQENPVAFYEKLEKLADRMEKHSLWVIFE
                     NMPKKMPPEMSVRTAKFLMHLPEECHAILIGRECPEREFLKLIWKRKMELFPQELLLFE
                     REEIRNFVEAVGSPLNPDEILKETGGWAGCVDMMLRMSVIQISGVHKRSHSVEELRQSY
                     EITSYIKSEILETLTSEEQELMRRTAVCPWVNEKLCADVWGIQWAEDCLNILGRKGILV
                     HDMHLNRWKTAPLFQSVCSVSYNSFRFWIRLGQWYDGHGFVKEALQCLKLSGKEKEIYS
                     CMIRNYQKVPFSGISFDEVMKWKESIPEVCYLRGMYCYFHQNFEGLNREIIRLNKMDSD
                     EKKKKEIILNLTYVKPDMSLEKWLNLLESYAQKAGTFSLYSMLGNSVTYLCGLRDLSEL
                     FACTRKEENRKAHLWRECLGENEYTGYCLARLDYYLEIQQKDAIRDEDWDVIREGTDQD
                     FWQLRLARMYLLCKFQTMQPDEEIAEYIRYLRETLVYEENEWCVRNVDAVDNLFFDRTN
                     KRERFSVWLLHSEDDLRQDLNEDNYLLFFCLAKGFILINQYEKAERIHRKLIPYLQCYR
                     RSYLLAEILFQQAIIYWEGRESSQMLRSMIESFMISGEYRYVRMYIDYGNRGRGVLEAY
                     IEWLRSSRPEGWHRKKKYNYGNVLRMPLEDYMETVLRLAKRETKYVLPLQDHSVEEKLT
                     IMETVILQDLAVGASNAEICKELNLKLPTVKSHIYSLYKKLNVKNRIQAVLKGKELGIL
                     K"
     CDS             complement(9643..9915)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_8"
                     /sec_met_domain="PF05402 (E-value: 1.8e-19, bitscore: 59.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.1e-17,
                     bitscore: 51.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDKKFVLREIAGEYIIIPTGKTALDFKGLITVNEVGVSIWKML
                     QNDVTLEELVQGILNEYEVEEEVAREDIQEFLDALIAGGILKQDV"
     CDS             complement(10100..11344)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_9"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.8e-53, bitscore:
                     171.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEIQEKFLEALRVSLKNGTVWWEEPLQPGQWRELFGLAETHHVL
                     PLIYEAVYRSPAAGQADPRLMMDYKWKTVQLTSLQALKTESFLCLMESLNRQGVYPVTV
                     KGIICRNLYPKPDCRISGDEDILIPKEQFHKCHQVLTESGLKVADENQDTEKEYEVSYT
                     ARKGTLYIELHKSLFPPESNAYGDFNRFFEQADEHCVKIETEGRKVRTLGHTDHFFYLI
                     CHAFKHFLHSGFGIRQICDIILYASRYGSEIDWNRVLKQCREIHGEYFTAALFQIGEKY
                     LDFHADSAGIPKKWQAMKVDETMMLEDLLSAGIYGYGSKSRMHSSNITLNTAADQWHGR
                     HSSNILKALFPSAGEMEKKYSYLRKHKWLLPVAWITRICRYCRETITRSDQTATEALQI
                     GKHRVKLMKTYRIIK"
     CDS             complement(11349..12221)
                     /locus_tag="ctg59_10"
                     /transl_table=11
                     /translation="MFISGKKLKSCLLYLLIILITLSAASLLASKYALSVTHITASTGK
                     ISSSLRIVQLTDLHDSSFGRGNSRLIRKVREQDPDVILITGDLVNAKQENTEIAVNLIK
                     NLVKIAPVYCSDGNHEVEYQENYGTDLHELYREAGAQILDREYQDVEIAGQQLRIGGIY
                     GYCLPAKYESEARADETEFLTRFQDTDRLKILMCHMPVCWVINESLDEWNVDYVFAGHV
                     HGGEVILPFAGGIYAPDMGWFPGRLEGEFKSKDQERTLILSRGLGTTEMIPRFNNIPEI
                     MVVDIDGEK"
     CDS             complement(12227..12328)
                     /locus_tag="ctg59_11"
                     /transl_table=11
                     /translation="MMDNKDCAEYFPYNIIDELRAKFGIQAPEAVRR"
     CDS             complement(12325..13857)
                     /locus_tag="ctg59_12"
                     /transl_table=11
                     /translation="MSKKKRNRNIWILIPVCLCAILVIANLIQYFYFYRVLDELYEICK
                     KTSGENVSAFIGYANNLETNSLLTTGLTIISITVAIWLGLNIYNVVNKQDVEDTLESYK
                     ETQKEVFENYEKRIDDSDEEREKKVQYLTRKTEFANLLYLTGERYYASDFFANLFWNTK
                     VEYNNIDSIIKYEKKYIYCCRCYENNEKAKANMLACDLAERYWDLMCEQPYTIWAETDP
                     MKNFLRMRLADILFYKNMTANAFHMEEAKASVNYYEEIMDHPNEIKLWDDEIRAYFCNS
                     QGYMLYQMSRHVPDRDKKEEYLDKALEKLDYAVSKAPYKGRYRRNLGLIYQSRDKYEEA
                     RETYIAAFKTDPLDYKAYNTVVALDLKAFDKDSGIDDRNEILLDEIVFKDEIKQKWQSI
                     IDQDISWCKTAEKLCFSFVDTHYNMAKAYLYKYICEERTDSRLLELANEQINIAEELNP
                     DAPGTVFIRRNIYEAEGNFVKAYECVGENLIKRNDKNAKLRNRYEEKIKQML"
     CDS             complement(13946..14800)
                     /locus_tag="ctg59_13"
                     /transl_table=11
                     /translation="MAQGIFGGATSYEEQSLTDIDLDIQKWIKYTEEIKKMMNSWLEES
                     KRNGFWEKVDFDFQMTIYSSISYYDTIISDMKMVHEAILYGTITKREVKLLQKIGRKAF
                     SYNNEYPKTYKSERRYWHDYGNPQFQIVENMYAKGRDYFVTLQDAANAAARLEDYMSSQ
                     NVSNNTMNISGDVIGSQIQQGTVSSTQNMQENKEFDYDKVLEALKKIEQYSNNNLFEEE
                     FGDKAKEVRVIISEAIDDTAKHKEPFKIKRNFSKIKQLAEGVTTGIIASGIVELIKQIP
                     NLF"
ORIGIN
        1 actaaccccc ataaacatta aaaaataaca tttatgaccg gttaatgcct gcctgtccag
       61 taacacacca aatctgttct ttactataac tggtttttga gcgtttgtca ataaaatttt
      121 tattatgcaa atctctccat cacgatgaac cctataggaa acatctgaac tgttgccacc
      181 agccccaata accagaacaa agtcattata ccacagtcca ttcatttatc tctgaattaa
      241 ataatgtggc ataagcatgg tatttttcat cgaatctcgt atgctgatag aaaaatatat
      301 gttctaattc cgtttactct gttgtatcat atgtacggac catcattaga cgactgtatc
      361 cctgtgcata atgtgaagga gataccgtct gacttgtttc tgcttcaagc tcagttacct
      421 ttacattgta agtaattcca ccaacataga ttcccttatc ttccatataa agcttgtaga
      481 aaatccggac acagggaatt gtttcttctg tcagatttgt tactgtaaat gtattatcat
      541 cattcggtgt aacctgtacc ttgtcttcag acattccaaa accatctact ttcgcagcgg
      601 ttccaacgca ttctgtataa gtaccggact ggtatgcttt cttatttttc tcctgcacca
      661 ttaccgaagc ccctgccgga atatctgacg cttcaaattc cagctgttca ccattacact
      721 tcacagaaac agatacatat tcaactgcat tgctgcctga gttatacatc tgcatagcag
      781 aaacattaga aatttcctga tccgatccgt cctccacata aatcccactg taggaagata
      841 tgttttgaac tgtgatacct gtaccgggaa catcatatgg aaactcaaca ggttcagcct
      901 ggctttcctt tggtcctgtt tcctgtgcac cgctgtcttt atctaccagt ggaccaacat
      961 atatctcatc tgtatcgtca gaggactgct gcgatgcatc ctcagtatca gtcttctctt
     1021 cttttttcgc tttattcttc tttttcttta cttcagtcct tttcgtttcc tttttcactt
     1081 cttttttcgc ttcttcagta gcagattttt cctgctctac cttttctgca gatgtctcat
     1141 ttatcttatc ttttctattc agtgcaaaaa aacaagccac aataatcagc actatacata
     1201 aaacacccaa aaacaatgct ttcttcttat tcattacact ttctcctttc ttccagtatt
     1261 tcctgtttaa ccttcctgac ggcatcaggc atagtcttta ccatctggca tctgtattcc
     1321 ggtatgtttc caaattttcc attctctgta atttccatcg cagcacaact tttacaaata
     1381 tctctcttcg cacaagcacc acattccggt gcaagcctta tcctggcagt ctcttccagc
     1441 acacgtttcc agttctttgt aaaaccttcc tgaaatacat tatgttcttc ctcgccccga
     1501 aacatcccgc agggaaccat gcatccattc caggtaaccc agaagctgct ccttcctgca
     1561 tgacatctta caccctctgc tttcatctca ccacagatat catcattcaa ctccggaagt
     1621 atattttcat ttctgtcagc ccactccaga aatttctcgt cccccaaaga atatgcttta
     1681 atccttgcat cataataagc tgcttcctct ggactaaaac gatcattcac acctacactg
     1741 gaagcatctc ttcggacagg cggatacatg taactggctg cacgcacagg aatatattct
     1801 cttcttccga acgcaaaaat atcctccaga tcgtctgcat tatacggtgt cacactacaa
     1861 ttaagtctaa cattgatccg tgcctctttc aaaagcctga ttgcccgtga tacctgcgta
     1921 aacccctttg gatttctgca taagcgtcca taggtcacat ctgatgcacc atataatgtg
     1981 atattaattc tctgaggtgg aacttctctt aaccatgcga ccgtctgctc atcaatcaac
     2041 gtaccgttag aattaatttc tatgataatt cccagatcat acaatccctg ataaatctcg
     2101 cggaaatctt tcctcagaaa tggctctcct cctgtaagaa gaagatacag cattccgcta
     2161 tccctggctt cttttcccac ttccagccac tgctctacag ttcctaaagg tgcaatcttt
     2221 tcctgctctt ctctgttcat tcgcacatag cacattctac agttcatgtt gcaaagaggt
     2281 gtcagttcaa aaataccact aagtggtatt ttctgcctta cagcctttgc catcaaatac
     2341 tttgtaatcg gtgccgatac ggaactcatt tccattcttc atcctccttt tgatattcta
     2401 atactgtctt cgccaattct acagcacttt tttccggcag gcattcaagc atataaattg
     2461 gtacctgtgt agcaaagcat atcagataat ccatgattgt attcaaaaac tccttatccc
     2521 atcgatgaac tgtaacttcc ggatacagat acctgagtgc ctccggcagc ggaagtttgc
     2581 ggatactgtt ttttcctgcc ttgcgaataa caaaaactat ttttacaggt gcggactcat
     2641 ttctgtatat tccagatgtg cctgcatatg gcatgccgta tgcatgccat tcatcatcct
     2701 tcatcctcag agcagctctg tctccgttga gaatttctgc tttttcatat ttttcccaca
     2761 gggatgcctg tgttgacttt ccatagccgg atggcgcaga aaaaagaatt ccctttccct
     2821 tccatcgaat aaaagaagca tgaagtataa atgtcttatt caaaagaaaa atgctctcca
     2881 ttcccaaaat attaaacaat ttccgagaac aatttaacat atgaacatat ttttttatat
     2941 atctgcatat tattctgtta tttttatttt ccaggcaggc atatggaaaa tctccataag
     3001 aatatacgta tattttttta tattcccctt cttttacttc atatctattc tcaaccttaa
     3061 tacctccgct ctctattaca gtaatcttat ccacaggaga gaacctaacg tatacctgat
     3121 tatcttcaag cttttttaac tcttttatgt ccacagattt cagaaaatct tcagaatctt
     3181 cctcaatctt aataggaaaa gaactctcta caaatatgca aatttctgca atggtgtata
     3241 aatataacat tattttttcc ttttattcaa tctatctcaa tagtccgtgt aatatcagaa
     3301 atgcagccat ggaaaccatg accgcatttt ctatataaat ataaatttaa aaattgctat
     3361 ttatcttaca gaatattttt gttccataaa atatacttaa gatgcaaacg gactagcaga
     3421 attccataaa ccattgtaac aatctgcttc agttccctga tcctttggat ctaactcgca
     3481 agaaagaaca ccatcatgaa agaacgcgtt ccacgaacat gtaaattcag atccaaactc
     3541 agaagttcca ggctctgcac cacaactatt tgcaaaattt ttgtccacgg taaatttttc
     3601 tatataaaga accggttttt tgtaaacttt tttcatttcc ttctcctctc taaagccatc
     3661 cattaaatcc ctggaacagc ttattcagcc aggaatgaat tttgtcaatt ggtttctgat
     3721 cctcattcgg ttccggatta gtaatatcta catttccatc gtctggttca gttacctctg
     3781 tattctcatc ctgaccagaa tctggtgtcc cttccacagt tttgtcttca taaggaactt
     3841 ctgataatgt atcaaacaca tttgcatatt ccaccagttt caaaactaac ggattttcca
     3901 aaacactaac agattcttct gcttccggta cttcttctgc ttctgctgca aataaatctg
     3961 tattatctgc ttctggcata tcaccatctg aagcatctgt aaactgagag ccgtcatcaa
     4021 aggcgtctgc tgatgttgca gaatacgtta ctgtttgtgc actttcggta tctgatatac
     4081 cttcgattcc tccaagctta ttgttatagt agattttggt aatagctaat aaattatcac
     4141 ctgtgttctc aataacaata catcctgcat agtctccttc tgatacaggt gttatcttat
     4201 aatacaaatc tgttgaatgt ccaatctctg ttgaacttgc atttttatca ttagtaagtc
     4261 ttaccgttgt cttaccttcc ggtgctttta atccaacata atagctagct tttgaatcaa
     4321 taactttaaa ggctatcttc tgtccctttg ctaaatatac ttcattcttc ggaccataat
     4381 ccctaaattc ggctacttta ttacttgttt tactattatc gtctgttgtt ctatccagga
     4441 acactatcgc tccatttgct aactcacctg tcgttgtacc tgtgtctaat aagatgtcac
     4501 gaacttcctt aaatgttgca ttcagcatat ctgttccata cgcctcgcta acaactgcat
     4561 ctgtttcttt attctgaatt ggattataaa cacgtattcc atctaaataa tatgtgccac
     4621 gtctatcctc agtgcccttt ttaccagctg ccactactac aagtttaact tcatatttac
     4681 cataatccaa tgggccaaat gataaagtcg gaatctgata atagtcacca gacgcagact
     4741 tattatccat gctaaccgct ttcactactt tctttccatc agtagttatc gagcttaata
     4801 tcgcagatac tttacccact gtaccattag tgcgactata gatatccaca ccggttcctg
     4861 agaaagtgaa tgtcgcagtt gctgcctttc cagtgtcacc tttgttatct gcatcagcca
     4921 tatgtgcact accgtcacta tatttcgtgt cattagaaag atccgtattc gtccatccac
     4981 catgaatatc tgtattcacg gattctgtat ttgcggaacc taaatttgaa gtatctgtcg
     5041 tccaattacc agtatattca ataccaactg ttcccgcttc attgttggtt tcaaaatcat
     5101 cctcataata tacattatta gcaggaagaa cactgactct ggaccaaaga ttatcattac
     5161 catttatctc tttaatatca ttgtccgtcg tctcaccaaa tgcataaaat ttgtcataac
     5221 catcccagtt agttgttttt ggagaataaa caaggttctt taatgaacca tacttaggtg
     5281 catagcttgc atctttctca ccaatacttc ctgtaattgc catattatca gaagacatct
     5341 tccaatctga tggcgaaagc gttacaggtt ttgcatagtc taaaacatat gctttatttg
     5401 ttaaaacgac ctgtggccgc gggaatttag cagccggctc aggtgcacct tctgcataaa
     5461 tacctgaagc ctcattgttt gtgtaaacct tctcacctgt ggctgctgaa tcttttggaa
     5521 ttactccctt aatcgtaaca accagctttt caccattatg tctcggtgca atatattcat
     5581 tcgaataatc gaagtcagta acattaattg tgttatcgtc tattgttgct ttaatatcct
     5641 ttgacttact ttcagtcccc caactaatgg aatttccatc ttcagtggaa ccaggtacag
     5701 ttgaaacggt aattttatct ccggcattat atccttccgg aagtgtaaaa tcatctgaca
     5761 gaatatcttt cataacagca tttttgttta aagcaactgt cgtacttggt gttgtaattg
     5821 tatttgaaat acttgtaaat atcttattca aaccatccgc actggtcgca gccagataat
     5881 agccattgtt gccgcctttt ccagaattgt ctaatttctc tgctgacgga tagttcgttg
     5941 aaacatagtt catatattta ttaacatctg atgttgatga cggatcagca ccattaaaaa
     6001 caccaattgt ataaacagta gttccctgat ctttaagacc ctttgatgta ccaattgcat
     6061 cattagctat attttcatca aaggtatccc aacttgtagg ttttccatcc gtaaacataa
     6121 ttaccagctg tttacgtttt gaatcatccc caagactatt tgcatccaag atgtctttgg
     6181 ccattgtcat accaagatct gctcgagtag cgccattcgc atctaacgcg ttaatcgcat
     6241 tgttcagcat ggtgtttcct gcatcagtag atgtatcctg aaaggcattt tgttttgcgt
     6301 ctgcgtactt atcactatta tagctaactc ccacagagcc gctattactt ccatccacgg
     6361 aaagtatttc tgtattatta ccataatcgg actcagatgc aaatccaacc atagcaattc
     6421 tatggttaac tttatcagtt gtcgcttttt cttttactac accgacaaaa tttgacactg
     6481 catctttcag tgcatccaat tttgtggtaa tagttcttga atacagctga ctagcccaga
     6541 ttgtatcccc tgagcctgta taattacatt cccgcttatt tgtagtaact tcatcaccat
     6601 tcaaataata agatgtaccg tcctttttat agaaaagata atactttctc caagagccaa
     6661 ttccattctt ctcacgctga actttataat aatttccatc tgtatctaaa tagtacctgg
     6721 cagaactatt tatatcatca taagaataac tagtcttatc ctcaagagta taggtataac
     6781 ccatatcatc actcattgac ccagactgat ccagcacaag gacaatatcc aacggcacag
     6841 cctcttttgt tattgtcgtt gttgtttttc cggtagcata agcttccaga ttgattgtat
     6901 aagttccatc atcttccaga cgagcggttt tgcttaaatg catcccactt tctccagctg
     6961 ttccgctgtc atctgtgttg gctgccagta atgttgttgg tagcatgcca agcatcatcg
     7021 tcaatactgt cagaaatgcc agcacattac gaaatgcttt ttttgtttta ctttgcataa
     7081 taatctcctt tcccatacaa aaaactacat tccagtcatt ttgtattttc ctaaatttta
     7141 ctaaattata cccttcctaa cgctatttgt tccacatact aaagtatgga ttatttactc
     7201 tttttttata ttttctgttt tgctgtctgc tcttacttta atattcccag ctccttacct
     7261 ttcagtaccg cctgtatccg gttctttaca ttcagctttt tatataaact gtaaatatga
     7321 ctttttacag taggaagttt caaattcagt tctttacata tttctgcatt ggaagcccct
     7381 accgcaaggt cctgaagaat aacagtttcc attatagtca gtttctcttc cacagaatga
     7441 tcctgcagag gcaaaacata ttttgtttcc cgttttgcca accgcagaac tgtctccata
     7501 taatcctcca gcggcatgcg aagtacattg ccataattat atttcttttt tctgtgccat
     7561 ccttcaggtc tgctgctgcg aagccattct atataagctt ccagcacccc tcgtccccta
     7621 tttccataat ctatatacat tcgtacataa cgatactctc cacttatcat aaaagattct
     7681 atcatacttc ttaacatctg actgctttct cttccttccc aatatataat tgcctgctga
     7741 aacagtattt ccgccaacag ataagaacgc cggtaacact gcagataagg aatcagtttt
     7801 ctatgtattc tttcagcttt ttcatactga ttaataagta taaacccttt cgccagacaa
     7861 aagaataaca aataattatc ttcatttaaa tcctgtcgca aatcatcttc cgaatgcaaa
     7921 agccaaacag agaatcgttc tcttttattc gtccgatcaa aaaacagatt gtcaaccgca
     7981 tctacattgc gcacacacca ttcgttctcc tcatacacca acgtttcccg caaatatcgg
     8041 atatattctg caatctcttc gtcgggctgc atggtctgaa acttacacag caaatacatt
     8101 ctggctagcc gaagctgcca gaaatcctga tccgttccct ctcgtataac atcccagtct
     8161 tcatcccgaa tagcatcttt ctgctgaatt tccagataat aatccagcct tgccagacaa
     8221 tatccagtgt attcattttc tcccagacat tctctccaaa gatgcgcttt tctgttttct
     8281 tcttttctgg tacacgcaaa caactctgat aaatcccgta gtccgcataa atatgtaaca
     8341 gaattaccca acatactata taaagaaaaa gtgcctgcct tctgtgcata actctccagc
     8401 aggttcagcc atttttccag cgacatatca ggtttgacat atgtaagatt taatataatc
     8461 tcttttttct ttttttcatc agagtccatc ttattaagtc tgatgatttc cctgtttaat
     8521 ccttcgaaat tctgatgaaa ataacaatac attcctctta aatagcagac ctcaggaata
     8581 ctttccttcc acttcatcac ctcatcaaaa gatattcctg aaaagggaac tttttgataa
     8641 ttgcgaatca tacaggaata aatctccttt tcttttccgg ataatttgag acactgtaaa
     8701 gcctctttca caaatccatg accgtcgtac cattgtccca atctgatcca gaatctgaaa
     8761 gaattatagg atactgaaca tacactctga aaaagaggtg ctgttttcca gcgattcaga
     8821 tgcatatcat gaaccagaat cccttttctt ccaagtatat tcaggcaatc ctcagcccac
     8881 tgaattcccc agacgtcagc acacaatttt tcatttaccc acggacaaac tgcagtacgc
     8941 cgcatcagtt cctgttcttc tgaggtaaga gtttccagta tttcactctt aatatatgaa
     9001 gtaatttcgt aactctgtct gagttcttct acactatgtg atcttttgtg cactccgcta
     9061 atctggatca cagacatacg aagcatcata tccacgcatc ctgcccagcc accggtttct
     9121 ttaagaattt catccggatt aagcggactt ccgacagctt ccacaaaatt ccttatttct
     9181 tctctttcaa aaagtaacaa ttcctgtgga aacagttcca tctttctctt ccatattaat
     9241 ttgagaaact cccgttccgg acactcgcgt ccgataagaa tggcatgaca ttcttccggc
     9301 agatgcatca ggaactttgc tgtacggact gacatttccg gtggcatttt cttcggcatg
     9361 ttttcgaaaa tcacccagag actgtgcttt tccatacggt cagccagttt ttccagtttt
     9421 tcataaaaag ccaccggatt ctcctgttct gtatccatcc aaaaaacaaa atattccata
     9481 tccgggtatc tggataaaaa catcctgaca acagtagttt ttcccgacgc agcggctcct
     9541 tcaatataaa gagaagggaa tgtcgccatc cccttctcta aaaattctgt cttatctatg
     9601 taatactgtt ggttgttgaa aggttcataa tgagttttcg aactaaacat cctgtttaag
     9661 tattcccccc gcaatcagcg catccagaaa ttcctgaata tcttctctgg ctacttcttc
     9721 ttccacttca tactcattca gaattccctg aacaagttct tctaaagtaa cgtcattctg
     9781 aagcattttc caaattgaaa ctccaacttc attcacagta atcaatccct taaagtcgag
     9841 agctgtcttc cctgttggta taatgatata ctctccggca atttcccgaa gaacaaattt
     9901 cttatctatt ttcatactta catcttcctt tactttcgtg aatcattata acttctttct
     9961 gtattaccgt catcaacatt ttcattatat ataaaaattc tgttaaatgc aactgttttt
    10021 tatatgtttc cggacgttag tctgaatcaa tgattattgt ttacttcgtt ctcaaaagct
    10081 atttcaggca ggaaaattat cattttatga tcctgtaggt tttcatcagt ttcacacggt
    10141 gcttcccgat ctgcagtgct tctgtggcag tctgatccga tcttgtgatc gtttcccggc
    10201 aatatctgca gatcctggtg atccatgcta ccggcaggag ccatttatgt tttctgagat
    10261 aagaatattt cttctccatt tcccctgctg aaggaaagag tgccttaaga atattgctgc
    10321 tgtgcctgcc atgccactga tctgctgctg tatttaacgt aatattactg ctgtgcatac
    10381 ggcttttgct tccgtatcca tagattcctg ctgaaagaag atcctccagc atcatggtct
    10441 catccacttt catcgcctgc cattttttcg gaatgcctgc actgtccgca tggaaatcca
    10501 gatatttctc tccgatctga aacaaagcag ctgtaaaata ctcgccatgg atttccctgc
    10561 attgcttcag aacccgattc cagtcgattt cgctgccata acgtgatgca tagaggatga
    10621 tatcgcagat ctgacggatt ccgaacccgc tgtgcaggaa gtgtttgaat gcatgacaga
    10681 tcagatagaa aaagtgatct gtatgcccca gagtccgtac ttttctgccc tctgtctcta
    10741 ttttcacaca gtgctcatct gcctgctcaa agaatctgtt aaaatctcca tacgcattgg
    10801 attccggcgg aaaaaggctc ttatgcaatt ctatatacaa agttcctttt ctggctgtgt
    10861 aagaaacctc atattctttc tctgtatcct ggttttcatc agcaacttta agtccactct
    10921 ctgtcagcac ctgatggcat ttgtgaaact gctccttcgg aatgaggata tcctcatctc
    10981 ctgatatacg gcagtccggt ttcgggtaca ggtttctgca gataatccct ttcacagtaa
    11041 ccggataaac tccctgtctg ttcaggcttt ccatcagaca caggaaactc tctgtcttca
    11101 gtgcctgcag agaagtcagc tgaactgttt tccatttata atccatcatc agccgcggat
    11161 cagcctgtcc ggctgcagga ctgcgataaa ctgcttcata tattaaagga agaacatgat
    11221 gtgtctccgc cagcccgaat aattccctcc actgtccggg ctgcagcggt tcctcccacc
    11281 aaacagtccc attcttcagg gaaacgcgca gagcttccaa aaacttctcc tgaatctcat
    11341 tcatatttct atttctctcc atctatatct acaaccataa tttccggtat attgttgaac
    11401 ctgggaatca tctcagtagt tccaagccct ctggaaagaa tcagagttct ctcctgatct
    11461 ttcgacttaa actctccttc cagacgtccg ggaaaccagc ccatgtccgg agcatagata
    11521 ccgcctgcaa acggcaggat cacctctccc ccatgaacat gcccggcaaa aacataatcc
    11581 acgttccatt catccaggct ttcattgatc acccaacata caggcatatg acacataagg
    11641 atcttcaatc tgtccgtgtc ctgaaatcgg gtcagaaact ctgtttcgtc cgctctggct
    11701 tcactctcat acttcgcagg cagacagtac ccgtaaatac cgccgatccg aagctgctgc
    11761 cccgcaatct ccacatcctg atactcacga tccagaatct gcgcacctgc ttcacgataa
    11821 agctcatgaa gatccgtccc atagttctcc tgatattcta cctcatgatt cccgtcagag
    11881 caatacaccg gagcaatctt taccagattt tttatgagat tcaccgcaat ttccgtgttc
    11941 tcctgtttcg cattcaccag atcccctgtg atcaggatca catccgggtc ctgctccctc
    12001 accttcctga tcagcctaga attccccctg ccaaaactgc tgtcatgcag gtccgtcagc
    12061 tgtacgatgc gaagagacga ggaaatcttc cctgtggaag cagtaatgtg tgtcacagac
    12121 agcgcatatt tagaagccag caggctggct gctgacagag tgatgagtat tatcagcaga
    12181 tagagcagac agctttttaa ttttttaccg gatataaaca tagatactac ctcctgactg
    12241 cttctggtgc ctgaattcca aattttgccc gcagttcatc aataatatta tatggaaagt
    12301 actctgcgca gtctttatta tccatcataa catctgcttt attttttctt catacctatt
    12361 tcttagtttg gcatttttat catttctttt gattaaattc tctcctacac attcatatgc
    12421 ttttacaaaa ttcccttctg cttcataaat atttcgtctt ataaatacag ttcccggtgc
    12481 atcaggattc aattcctctg caatattaat ctgttcattt gccagttcca acaaacggga
    12541 atccgttctt tcttcacata tgtacttata aagataagct tttgccatat tataatgggt
    12601 atcaacaaaa gaaaaacaaa gtttttcagc agtcttgcac cagctaatat cctgatctat
    12661 aattgactgc catttttgtt ttatttcatc tttaaaaact atttcatcaa gcaaaatttc
    12721 atttctgtca tctataccag agtccttatc aaatgctttt aagtctaatg ctacaacagt
    12781 attatacgct ttatagtcaa gtggatccgt cttaaaagct gctatatatg tttcgcgcgc
    12841 ctcttcgtat ttatctctgg actgataaat aagtccaaga tttcttctgt atctgccttt
    12901 ataaggcgct tttgaaaccg cataatccag tttctctaat gccttatcca aatattcttc
    12961 tttcttgtcc ctatccggta catgcctgct catttgatac agcatatatc cctgggaatt
    13021 acaaaaataa gcccttattt catcatccca taacttaatt tcatttggat gatccataat
    13081 ttcttcataa taatttacac ttgctttcgc ttcttccata tggaatgcat tcgcagtcat
    13141 atttttataa aacagaatat ctgccaaacg cattctcaga aaatttttca tcggatctgt
    13201 ttcagcccaa atcgtatacg gctgttcaca cattaagtcc caatagcgct ctgcgagatc
    13261 gcatgccagc atattagctt ttgccttttc attgttttca taacatctgc agcaataaat
    13321 atactttttt tcatatttaa taatactgtc aatgttgttg tattccactt tagtattcca
    13381 aaacagattg gcaaaaaaat cagatgcata atatctctca ccagttaaat aaagcaaatt
    13441 ggcaaattcc gtttttctgg taagatactg taccttcttt tctctttctt catctgaatc
    13501 gtctattctt ttttcataat tctcaaaaac ttctttttgc gtttccttat aactttccaa
    13561 cgtatcttct acatcttgtt tattcaccac attataaata tttaatccaa gccatatcgc
    13621 aacagtaatg ctgataattg taagccctgt agttaataaa ctatttgtct ccaaattatt
    13681 ggcataccct ataaatgccg acacgttttc cccagaagtt tttttgcata tttcatatag
    13741 ctcatctaac accctgtaaa aataaaaata ctgaatcaga tttgcaataa ccaatatagc
    13801 acataaacaa acaggaatta aaatccaaat atttcgattt ctttttttct tagacatatt
    13861 tcatccttcc tacatagtca aatctgtttt tccttataaa tcaaagattt agtcaagcgg
    13921 atattccgat ttctgtaatt cctgtctaaa ataaattagg tatctgtttt attagctcaa
    13981 caataccact agcaataata cctgttgtca caccttcagc cagttgcttt atttttgaaa
    14041 aattcctttt gattttaaat ggttctttat gcttcgctgt atcgtctatt gcctcactga
    14101 ttattacacg tacttcttta gccttgtctc caaattcttc ctcaaacaga ttattatttg
    14161 aatattgttc aattttcttc aacgcttcca gaactttatc ataatcaaac tctttgttct
    14221 cctgcatatt ctgcgtagag ctaactgttc cctgctgtat ttgtgaacca ataacatctc
    14281 cggaaatatt cattgtatta ttactaacat tctgactgct catataatcc tccaatcttg
    14341 ccgcagcatt agcggcatcc tgtaaagtta caaaataatc tctgcccttt gcatacatat
    14401 tttccacaat ttgaaactgt ggatttccat aatcatgcca atatctcctt tcacttttat
    14461 atgttttcgg atattcatta ttatatgaaa acgcctttct tcctatcttt tgaagcaact
    14521 tcacctcacg cttcgttatc gttccataca gaattgcctc atggaccatt ttcatatcgg
    14581 aaataatagt atcataatat gaaatagaag aatatattgt catctgaaaa tcaaaatcaa
    14641 ccttttccca aaagccattt ctttttgatt cctccaacca cgaattcatc attttcttta
    14701 tttcttccgt atatttaatc catttttgaa tatccaaatc aatatcggtc agagattgtt
    14761 cttcatacga agtcgctccg ccaaatattc cctgtgccat ttaatcttcc tctcttactg
    14821 cttactcatt cttatttata tggattgtgt catttatctt caccatataa caaaaaatgg
    14881 tttctgacta tcacatattt aaatcaaaat aatgataaca tgaaaccatt tttatataaa
    14941 gtaaaaaact actctctttt aatctttctc tggaaactca aatactattt agaactttgg
    15001 atatctttac tctaacatag attattctta aaagcatttg aggaaataat ttactatatt
    15061 aacaccactt tacaactttt tcataaaaaa atatcgtaca ggactttctg gtgtataatg
    15121 aatttgaccc aaaacattac aaaggaaagt gaccctgtac gacaaaaaca ttatacaacg
    15181 aaaaaaca
//
