LOCUS       c00297_gnlPro..        10340 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CAIBLCGG_297.
ACCESSION   c00297_gnlPro..
VERSION     c00297_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:54:22
            Original ID  :: gnl|Prokka|CAIBLCGG_297
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10340
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10340
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3809:6753]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3810..6753
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..10340
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10340
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(3..1754)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     286.5; E-value: 2.5e-87)"
                     /gene_kind="resistance"
                     /locus_tag="ctg297_1"
                     /transl_table=11
                     /translation="MSRSTIKDPAKSKSSETFFKVLRFIGRYRFLLILSIILAAVSVIL
                     QLYVPILFGNAIDQVIAQHQVNFEMMWYYLSRILVMVILSSAATWLMNVINNRMTYQTV
                     KDIRAKAIRHIQVLPLSYLDGHSTGDIISRIIADTDILSDGMLLGFTQLFSGIVTIIGT
                     LIFMFSKNFWITLMVIVLTPVSFLVAKFISSHTFQMFRKQSDARGRQTALIEEMIGNQK
                     VVQAFGYEEKSSKRFAKVNEELQECSLKAVFYSSLTNPSTRFVNNIIYACVALVGAFII
                     PGGRLTVGGLSVLLSYANQYMKPFNDISSVVTELQNALACAGRIFDLLEEEPEVAEASE
                     TLKDVKGEVDIKNMCFHYDESKKLIEDFNLHVKPGMRVAIVGPTGCGKSTFINLLMRFY
                     DVNSGSISVDGKPIRDITRHSLRSSYGMVLQETWIKNGTVRDNISIGKPEATDTEIIEA
                     AKLTHSWEFIRRLPKGLDTMLNEDSLSQGQKQLLCITRVMLCLPPMLILDEATSSIDTR
                     TELQIQEAFERMMEGRTSFIVAHRLSTIRNADLILVMKDGSIIEQGTHDELIAKGGFYH
                     TLYNSQFA"
     CDS             complement(1751..3565)
                     /locus_tag="ctg297_2"
                     /transl_table=11
                     /translation="MRSLTVYLKNYKKESILAPFFKFLEVVFDLIVPIVIAQIIDVGIA
                     NHDNGYIVQRFSILILMAALGLASTITAQFFAAKASVGFATELRQAVYDHVQHLSYTEL
                     DTLGTDTLITRLTDDVNQIQNGLNMGLRLLLRSPFIVLGSMVMAFTIDFKCALVFAVAI
                     PFLFLVVFVIMFLSIPLFKKVQGKLDTVTGLTRENLTGVRVIRAFCREKEAVAEFDTRN
                     QELTKLNLFVGKLSALLNPVTYVLINIATVILIQKAGVEVNLGGMQQGQVVALYNYMAQ
                     MIVELIKLASLIITLNKSAACAGRVADILKVKSTMDYPSSSTYSAQISKDLATATADAS
                     LSENAIVFNDVTFEYSKAGAPSLSHISFSVKKGQTVGIIGGTGSGKTTLVNLISRFYDA
                     SKGTVLLDGQNIENYTRSDLRSRIGVVPQKAALFKGSIRDNLKWGREDASDEDLWQALT
                     TAQGKEVVEGKPGQLDFMLEQNGKNLSGGQKQRLTIARALVKKPEILILDDSASALDFA
                     TDAALRKSLNRLDWKVTTFLVSQRSSSIQQADLILVLDNGTLAGKGTHAELLRTCDTYR
                     EIYFSQFPEERARYSSVSAGNIMKEVTV"
     CDS             3810..5081
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg297_3"
                     /sec_met_domain="HGD-D (E-value: 5.1e-57, bitscore: 182.9,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWEAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLRPIQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERAFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPAFAIDVPWQPNEENVQYVADQLKELKIFLEKHTGKTISEDALKKRLACSKRTLEN
                     YKKYQQMRADRYVPSDLVSPLYAGMTNNILLGTEEEEKYTQMLLKDIKKAPAAKGKHIY
                     WMHTIPFWSDAVKQELCFSEKAQIVGCELAETCEPDFDPEKPFEAMARRMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     CDS             5074..6753
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg297_4"
                     /sec_met_domain="HGD-D (E-value: 9.4e-18, bitscore: 53.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 6.5e-66, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPEGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
     CDS             7417..8832
                     /locus_tag="ctg297_5"
                     /transl_table=11
                     /translation="MWEAINSFLTTVDNLVWGVPLMVLIMAGGILLTARLGLLQMRRLP
                     LALKWMFKNEEEGDGEISSFAALCTALSATIGTGNIVGVATAVCAGGPGALFWMILAAF
                     FGMATKFSEGLLAVKYRVVAEDGHSLGGPFYYIEKGMGTKWKWLAKIFAFFGVCVGLFG
                     IGTFSQVNGISSAVQNFFDPNKSNCVNIPFLGEYSWAVVISSLILAACVAAILIGGLKR
                     IATVSQIIVPFMAVIYLIFSVALILLNVTEIPAAIVTVVKGAFNPSAVTGGVVGTMIVS
                     MQKGVARGIFSNEAGLGSAPIAAAAAQTKEPVRQGLVSMTGTFIDTIVICTMTGLSIVL
                     TGAWQVEGLEGVQVTTYAFQHGLPIPGQISAFVLMICLVFFAFTTILGWDYYSERCLEY
                     LTNGHKKTILTYRWLYILAVFIGPYMTVSAVWTIADIFNGLMAIPNMIALFALSGVIVK
                     ETKAFFAAEKHKM"
     CDS             9151..10062
                     /locus_tag="ctg297_6"
                     /transl_table=11
                     /translation="MIYTVTFNPSLDYIVSVDDFKLGLTNRTSSELMLPGGKGINVSTV
                     LMNLGIENTALGFTAGFVGKEIIRRLHEMGVKSEFIQISEGVSRINLKLKSIDGTEING
                     AGPVISKDKVEELMKKLEELGEGDVLFLAGSIPSSMPDDMYEQIMARLDGKGVMIVVDA
                     TKDLLVNVLKYHPFLVKPNNHELGEIFGVELKTRKDVIPYGKKLQEKGARNVLISMAGE
                     GAVLVAEDGQVFEEPAPKGRLVNGVGAGDSMVAGFVAGWMEKKDYEHAFHMGIAAGSAS
                     AFSENLATKEEIEAVYRQITEK"
     CDS             10083..10286
                     /locus_tag="ctg297_7"
                     /transl_table=11
                     /translation="MRITDLLDRRSVSLTAAPKTKSETLEKIAPVLIYTVVGILIMGLL
                     MTFIVEPVSYCSHATVPRGVLA"
ORIGIN
        1 tttgcaaact ggctgttata taaagtatgg taaaatccac cttttgcaat cagctcatca
       61 tgagtaccct gttcaatgat acttccgtct ttcataacaa gaatcagatc tgcatttcgg
      121 atggttgaaa gcctgtgagc tacgataaag cttgttcttc cctccatcat tcgttcaaac
      181 gcttcctgaa tttgtaattc tgttcgtgta tcaatactgg aagtggcttc atccaggatc
      241 agcatcggag gcagacagag cataactcgt gtgatacaca gcagctgttt ctgtccctgg
      301 cttaagctgt cttcgttgag catggtgtcc agtcctttag gaagcctccg gataaattcc
      361 cagctgtggg taagcttggc tgcttcgatg atttcagtat ctgtagcttc cggttttcca
      421 atcgagatat tgtcgcggac agttccgttt ttgatccatg tttcctgaag caccatacca
      481 tagctgcttc tgagagaatg gcgggtaatg tctctgatcg gtttgccgtc aacggaaata
      541 gatccggaat ttacatcata gaatctcatc agaaggttga taaaggttga cttaccgcat
      601 ccggtaggtc ctacaatggc aacgcgcata cctggtttta catggagatt aaagtcctca
      661 atcagtttct ttgattcatc ataatggaag cacatatttt taatatctac ttcacccttt
      721 acatctttca gtgtctcaga agcctctgca acttccggtt cctcctccag cagatcgaag
      781 attctgcctg cacaggcaag agcattctga agttctgtaa caacggaact gatatcattg
      841 aatggtttca tatactggtt ggcataggag agaagtacgg aaagtcctcc gactgtcagt
      901 ctgcctccag ggataatgaa tgcacccacc agtgcaacac aggcataaat aatattattg
      961 acaaaacggg tggaagggtt tgtcaggctg ctgtaaaaaa cagccttcag actgcattcc
     1021 tgtaattctt cgttaacctt tgcaaagcgt ttagaagatt tttcctcata tccaaaagcc
     1081 tgaacaacct tctggtttcc aatcatctct tcgatgagag cagtctgacg tcctctggca
     1141 tcgctttgct tccggaacat ctggaaggta tgggaagaaa taaatttggc caccaaaaag
     1201 cttacggggg tcaggacaat gaccatcaat gtaatccaga agtttttgga gaacatgaag
     1261 atcagtgttc cgatgatcgt tacgattccg gaaaaaagct gggtaaatcc aagcagcata
     1321 ccatcggata gaatatctgt atctgcgata atacggctga tgatatctcc ggtactgtgt
     1381 ccgtcaaggt aagagagggg aagtacctga atgtgtcgga tggctttggc acggatatcc
     1441 tttactgtct ggtaggtcat gcggttattg attacattca taagccacgt ggcagcagaa
     1501 gagaggatga ccattacaag gatacgtgac aggtaatacc acatcatttc gaagtttacc
     1561 tgatgttggg caatgacctg atcaatggca tttccgaaca ggattgggac atacaactga
     1621 aggataacgg aaactgctgc cagtatgata ctgaggatca gcagaaaacg gtatcttccg
     1681 atgaaacgca gtactttaaa aaaagtttcg ctgcttttgc ttttagcagg atcttttatt
     1741 gttgatctgc tcatacagtc acctccttca ttatattacc tgcagataca gaggagtatc
     1801 tggctctttc ttccggaaac tgagagaagt agatttcccg gtaagtatca caggtacgca
     1861 gcagttcagc atgagtaccc ttacctgcca gagtaccgtt atcaaggaca aggatcaggt
     1921 ctgcctgctg aatgctggag gaacgctggg ataccagaaa tgtagttact ttccagtcaa
     1981 gtctgttgag agacttacgc agtgctgcat cagtggcaaa gtccagggca ctggcactgt
     2041 catccaggat caggatttca ggttttttta ccagggcacg ggcaatggta agtctttgtt
     2101 tctggccgcc ggaaaggttt ttaccgttct gttccagcat aaaatcaagc tgtcccggtt
     2161 taccctctac tacctctttt ccctgtgctg tggtaagtgc ctgccacaga tcctcgtcag
     2221 aggcatcttc ccggccccat ttcagattgt cccggataga gcctttgaaa agagctgcct
     2281 tctgtggaac aacgccgatt ctggagcgga gatcacttct ggtgtaattt tcaatattct
     2341 gaccatccag cagaacagtt cctttgctgg catcatagaa tctggagatc agatttacca
     2401 gagtggtttt tccgcttcct gtaccaccga taatacctac ggtctgtccc ttttttacag
     2461 aaaaactgat atgggaaaga ctgggggcac cggctttgct gtactcaaag gttacgtcat
     2521 tgaatacgat ggcattttca gaaagtgatg catcagcagt tgctgttgca aggtccttcg
     2581 atatctgagc agaatatgtg gaggaagagg ggtaatccat agtagatttc actttcagga
     2641 tatctgccac acgtcctgcg caggctgcag atttgttcag ggtgatgatc agggaggcaa
     2701 gcttgatcag ttccacgatc atctgagcca tatagttata aagggcaaca acctgtccct
     2761 gctgcatacc gccaagattt acttctactc ctgctttctg gatcagaata acagtagcaa
     2821 tattgatcag tacgtaagtg accggattta acaaagcgga aagctttcct acaaagagat
     2881 ttaactttgt cagctcctga ttgcgggtat caaattctgc aactgcctct ttttcgcggc
     2941 agaatgcacg gataacgcgg acgcctgtaa ggttttctct ggtcagtccg gttactgtgt
     3001 ccagttttcc ctgtactttt ttaaacagag gaatactgag aaacataatg acaaagacaa
     3061 ccagaaacag aaacgggatc gcaacagcaa aaaccagggc acatttaaag tcaatggtaa
     3121 atgccatgac catggaacca agtacgataa acggacttcg aagaagaaga cgaagtccca
     3181 tatttaatcc gttctgaatc tgattgacat catcggtgag tcttgtgata agagtatctg
     3241 ttcccagtgt atccaactct gtataggaca gatgctgtac atggtcataa actgcctgtc
     3301 ttaattctgt ggcaaagccc acgctggctt tagcggcaaa gaactgagct gtgatggtac
     3361 tggcaagacc aagagccgcc attagtataa gaatagaaaa tctctggaca atgtatccgt
     3421 tgtcgtggtt tgcaatacct acatctatga tctgtgcaat gacgataggt acgatcaggt
     3481 caaatacaac ctccagaaat ttaaaaaatg gcgcaaggat gctttctttt ttgtagtttt
     3541 ttaaataaac cgtcaatgaa cgcattttaa aaattccttc ctttcgtaaa aaatctttcc
     3601 tatattattt cttccttttt ttgaaaaata atacattcaa aagtgtatca tttgagactt
     3661 ttttgtcaag aagaatgtgc aaaaacagat gaactttgga gaaaattcag cttgacttca
     3721 aaaaaagata ttactaaaat attccgtagc gctatttgta cgctggcaac tgataaatta
     3781 ttattaccat aatgaggaag agacagacta tggagattat tgagacattt ggtcattatg
     3841 tggaaaatct gacggataaa aagcctcagt cagcccgccg gctgttaaaa accggctggg
     3901 aggcgcagaa tctgaagttc cgttatatgc aggacaagag actgatgcct gcagacaggc
     3961 atcttgcaaa tctgatgatg gataccatgc tgcggcccat tcagaaaccg gaagattctg
     4021 ttattgtaag tatttttaca ccctgcgaaa tgatgcagga ggtgggatta catccctata
     4081 atgtagaggg attttcctgc tatctttctg caagcaaagc agagagggcg tttctgcagc
     4141 aggcagagaa tcagggaatt gcagagacac tgtgcagtta tcacaagaca tttcttggtg
     4201 cagcgcagaa aggacttctg ccaaagccga aatgtattgt ttatactaat ctaacctgcg
     4261 atgctaacct gttgacgttt cgtacacttg ctgattttta ccaggtacct gcatttgcta
     4321 ttgacgtacc gtggcagccg aatgaggaga atgtacagta cgtagcagat cagttaaaag
     4381 aactgaaaat atttctggaa aagcatacag gaaaaacaat ttctgaggat gcgttgaaga
     4441 aacgtcttgc atgcagcaag cggactctgg agaattataa aaaataccag cagatgcgtg
     4501 cggacagata tgtaccgtcc gatctggttt cgccgctgta tgcgggaatg acaaataata
     4561 tcctgcttgg aaccgaagaa gaggagaaat atacccagat gcttcttaag gatattaaga
     4621 aagcacctgc agcaaagggc aagcatattt actggatgca taccattccg ttctggtctg
     4681 atgcagtaaa acaggaactt tgcttcagtg agaaagccca gatcgtgggc tgtgaacttg
     4741 cagaaacctg tgagccggat tttgatcctg agaaaccgtt tgaagctatg gcaagaagaa
     4801 tggtatatca ttcgctgaat ggaagtgcac tgagaagaat cgaagctgga attcgtcatg
     4861 caaaacaggc cggtgctgat ggtgcggtgt ggtttggaca ttggggctgt aagcataccc
     4921 ttggtgccgc ccagcttgca aagaaaaaat tcgaagaagc cggtctgccg cttctgatcc
     4981 tggatggaga cgggtgtgac cgaagccacg gaggagaagg acagacatcc accaggctgg
     5041 gagcttttct ggaaatgttg ggaggtgctg agaatgaata aaacttatta tgtctgtaaa
     5101 tataccccaa ttgaacttct ggaatctctt ggcggggaat gtgagaactt taatcatatg
     5161 ccggagggat ttgacctggc cgatcaggtt tcacatccca atatctgcgg ttttggaaaa
     5221 acacttctgg aaggagtcat ggagggaaaa atcaaggaac ttgtcctggt gagctgctgt
     5281 gatactatcc ggagtgtcta tgacattctg ctggaaagcg gcaagctgga ttttctctat
     5341 attttggatg tgcttcactg tgacagtgcc tgcagcagag agcgtatggc tgtacagtta
     5401 aaagggctgg cgaaggctta tgcacagtac aaaggcacag agtttgatgc cggaaaattc
     5461 cgggctgctt tccatgcaca ggagaaaatc acaaagtccc atattgcagt gcttggcgcc
     5521 agaatggggc aggaattatt tgaaatgacc agcaaagcta tgcctcttcc tgtagagaat
     5581 gatacctgcg tgcataaccg ttctgtggga aatatacttc caccggaggg tgcttctttt
     5641 gatgagctga tggactggta tgcaggtgag attctggggc agattccatg tatgcgtatg
     5701 atggacccga caggtcgtaa gaagctttat aatgatccgt ctgttgcggg gattatttat
     5761 catacagtga agttttgtga tttttacagc ttcgaatatg ctgagatcaa gaatcataca
     5821 gatgtacctc ttttaaaaat cgaatcagat tatactattc agagcagcgg tcagcttctt
     5881 accagactgg aagcttttgc agagagcatt cagcctgaaa cactggagca gaccatagat
     5941 ggagacacaa aaggagagag aaaaatggga aaaggttatt tcgcagggat tgacagtggt
     6001 tccaccagta cagatgtggt gattttaaat aaagatcatg agattgtgac cagcattatc
     6061 ctgcctacag gagcaggagc tgctatcgga gcagaccgtg cccttgcaga ggcattgaag
     6121 gaggccggat tgcagagaga agatattgat gcgctggtta ctaccggata cggacgtaca
     6181 gctattaaaa atggtgataa gagtatcaca gagatcacct gtcatgcaag aggtgcgcat
     6241 ttcctgaatc cggaagtccg tactgttatt gatattggcg gacaggacag caaggtgatc
     6301 cgactggatg agaacggtgc agttgcaaac tttgttatga atgacaaatg tgcggcagga
     6361 accggacgat ttctggaaat gatggcacgt accatggaaa tgaatctgga tcagatgagc
     6421 gaatgtgggc tggaattcaa agaagatatt acaatttcca gtatgtgtac agtatttgca
     6481 gaatcagaag ttgtatccct gatcgcccag aataaggcaa cagatgatat tgtccatggc
     6541 ctgaataagg cggttgccgt aaagactgcc gcccttacca gacgtgtggg cggtgaggag
     6601 aaatatatga tgaccggtgg tgtttctaag aataagggcc tggtaaagac actggaagag
     6661 aagcttggaa caaagctggt gatcagtgac aaggctcagc tttgcggtgc acttggcgcg
     6721 gcactgtttg cggctgatat ggctgatgtg taaattttta gttactgttc actccgttct
     6781 cagcaacacg cttcgcgatg caggaaatat gaacctcctt gtgcaatgct caaggagtat
     6841 cgtttgcttc gcaaacttaa tttatgctaa tcgcataaat tcgcgcggta tgtctcgggt
     6901 tttctgtgac cttcgctcac aaaaaacacc tcgctggata ttaccggtga acagtaacaa
     6961 tttttatact ttttttataa aagtttaatt ttctattgac gagttcaaat ttaagagcta
     7021 tagtatacca cagtaacagc aaattaacga ggtgaagttt gcaggaaaga ggaagccaca
     7081 caaaaggcta tacccgccga aggagtaaaa ctctcaggtt ccctggatgc agggaagaac
     7141 tgcaaatgga tcgtttctct ggagacaccc gttagatcgg gggccgaagg tgcaaataac
     7201 acggaatgct gataacttcc cacaattggt tatctgaccc gtgtcttgaa tctctcaggc
     7261 aaaaggacag aggatgcttt atcatccccg ctgattcata tgaactatat gaacagtatt
     7321 ttctgaactt ctgatttttg aaacggtctg ttattacttt gtttcccagc tgtacaatat
     7381 attacacttt ttaaaagaaa aaggagattt attattatgt gggaagcgat taattctttt
     7441 ttgacaacag tagacaatct ggtctggggc gtgcccctta tggtcctgat catggcaggt
     7501 ggcatcctgt taactgccag acttggactt cttcagatgc gaagactccc tcttgcattg
     7561 aaatggatgt ttaagaacga agaagaaggc gatggtgaga tttccagctt tgcagcttta
     7621 tgtacagcac tgagcgccac aatcggaacc ggtaatatcg tcggtgttgc aactgctgtc
     7681 tgtgccggag gtcccggagc tttattctgg atgattcttg cagcattctt cggaatggca
     7741 acaaaatttt ccgaaggtct tcttgcagtg aaatatcgtg tggtagcaga agacggtcac
     7801 agccttggcg gtcctttcta ttatattgag aaaggtatgg gaacaaaatg gaaatggctt
     7861 gcaaagatct ttgcattctt tggtgtatgt gtaggtcttt tcggaatcgg tacattcagc
     7921 caggtaaatg gtatttccag tgcagttcag aacttctttg atccgaacaa atcaaactgc
     7981 gtaaatattc cgttccttgg agagtattcc tgggcagttg taatttcttc cctgattctt
     8041 gcagcctgtg ttgcagcaat cctcatcggt ggtctgaaac gaattgcaac agtcagccag
     8101 attattgtac cgtttatggc ggtgatctat ctgatcttca gtgtagcgct gattctttta
     8161 aacgttacag agatcccggc agctatcgta acagttgtga agggagcctt taatccgtca
     8221 gcagtgacag gcggtgtggt aggaacaatg atcgtatcca tgcagaaagg tgtggctcgt
     8281 ggtatttttt caaatgaagc aggtcttggt agcgcaccta tcgcagcggc agcagctcag
     8341 acaaaagagc ctgtacgtca gggtcttgta agcatgactg gtacatttat tgatacgatc
     8401 gtgatctgta caatgacagg tctttccatc gtactgacag gtgcatggca ggtagaaggt
     8461 ctggaaggtg ttcaggtaac aacctatgca ttccagcatg gacttccgat ccctggacag
     8521 atttctgcat ttgtattaat gatctgtctg gtattctttg catttactac aattcttgga
     8581 tgggattatt acagtgaaag atgtctggaa tatctgacaa acggacataa gaaaacaatc
     8641 cttacatacc gctggcttta cattctggca gtatttatcg gaccgtacat gacagtaagt
     8701 gctgtatgga caatcgcaga tatcttcaac ggactgatgg cgattccgaa tatgatcgca
     8761 ttgttcgcat taagtggagt gatcgtaaaa gaaacaaaag cgttctttgc agcagaaaag
     8821 cataaaatgt aaggaatcaa aagtaataaa ataacagaaa acagtaaatc ctctgattat
     8881 ggaatttata gcaatcctga tcagaggatt tttttgctta catttgactg attatgactt
     8941 ttttgtgcaa agtgaaccaa aatcagtcat tatttttatg gattagtttg attgactttg
     9001 aacgaatatg acagtatact aagaacgtaa acaaaaaaca gtcacgaaca tgcagaaaag
     9061 acatgacaat atgtactttt ggaatctttt ggtgcaagtg aaataaagac tccgaaagga
     9121 taccaatata aaacgggagg gaaagaagag atgatttaca cagtgacttt taatccatct
     9181 ctggactaca tcgtttcggt agatgatttt aaactggggc tgacaaacag aacaagttca
     9241 gagctgatgc ttccgggggg aaagggaatt aatgtttcca cagtccttat gaatcttggg
     9301 attgagaaca ctgcacttgg atttaccgca gggtttgtag ggaaagaaat tatccgtaga
     9361 ttacatgaga tgggagtaaa atctgagttc attcaaatta gtgaaggggt ttcaagaatc
     9421 aatctgaaac tgaaatctat tgacggaacc gagatcaatg gtgcaggacc ggtgatcagc
     9481 aaggataaag tagaggaact gatgaagaaa ctggaagagc ttggagaagg cgatgtactt
     9541 ttcctggcag gcagcattcc atcttctatg ccggatgaca tgtatgaaca gatcatggca
     9601 aggctggatg gaaaaggtgt gatgatcgta gttgatgcca caaaggatct tctggtcaat
     9661 gtcctgaaat atcatccatt ccttgtaaaa ccaaataatc atgaactggg cgagattttc
     9721 ggtgtagaat taaaaacaag aaaagatgta attccttatg gaaagaaact tcaggaaaaa
     9781 ggtgcaagaa atgtgctgat ctccatggcc ggcgaaggtg cagttctggt agcagaggat
     9841 ggacaggtat ttgaagaacc tgcaccaaaa ggcaggctag taaatggtgt gggtgcagga
     9901 gattccatgg tagcaggatt cgttgcaggc tggatggaga agaaggatta cgaacatgca
     9961 ttccacatgg gaattgcagc aggaagtgca agtgcatttt ctgaaaatct tgcaacaaag
    10021 gaagaaatag aagcggttta tcgtcagata accgaaaaat aataaagggg ggggaagaag
    10081 agatgagaat aacagacctg cttgacagac gaagcgtatc gttaacagct gctccgaaaa
    10141 caaagtcaga aactctggaa aagattgccc ctgttttgat ctatactgta gttggaatcc
    10201 ttattatggg actcctgatg acatttattg tagagccggt tagttactgt tcacacgcca
    10261 ctgtcccgcg aggtgttttg gcatgaatat gccaaaatcc cgagacatac aagccaaaat
    10321 tccattgccg caggcaatct
//
