LOCUS       c00004_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FFBOGIFK_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:52:36
            Original ID  :: gnl|Prokka|FFBOGIFK_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 43035
            Orig. end    :: 66284
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[53035:56284]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1513..2970
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_41"
                     /sec_met_domain="FGGY_C (E-value: 2.4e-37, bitscore: 120.9,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 2.3e-79, bitscore: 258.8,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEDSGKICNIVSKEYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRTQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKEKLSEYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSEDVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARSLGIKIERTKICGGGA
                     KSLLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(3082..4017)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_42"
                     /sec_met_domain="LysR_substrate (E-value: 1.1e-32,
                     bitscore: 105.5, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIEAVEKVMDIENNLENFLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFEHYIYQKEQ
                     LLLAVPKNYSINTRLQEYQIPIGEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELIFYKLPG
                     QSSKRTVFFYWKKGRYISRAMKEFLKLPFS"
     CDS             4167..5591
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_43"
                     /sec_met_domain="Lyase_1 (E-value: 1.6e-94, bitscore:
                     309.1, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 7.1e-22, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKAVEFDHVIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5700..7385)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_44"
                     /sec_met_domain="FTHFS (E-value: 5.2e-275, bitscore: 905.2,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGRTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKRVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_45"
                     /sec_met_domain="OKR_DC_1_C (E-value: 2e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 4.5e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVERLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_46"
                     /sec_met_domain="Spermine_synth (E-value: 2.5e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 3.7e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_47"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 3.1e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.5e-35,
                     bitscore: 114.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKVDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_48"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 3.5e-14,
                     bitscore: 45.3, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKDVCTRASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENGIRTLVLDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_49"
                     /sec_met_domain="PAD_porph (E-value: 4.4e-128, bitscore:
                     419.3, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGTFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTRED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14489..15367
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_50"
                     /sec_met_domain="CN_hydrolase (E-value: 2.2e-55, bitscore:
                     180.1, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTVEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15591..16052
                     /locus_tag="ctg4_51"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETEFPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIILLILIIGVAIPFFIILAIILYFLSWLKKRNNQ"
     CDS             16274..20983
                     /locus_tag="ctg4_52"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFSIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDVGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQLLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDEKSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAKDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGETETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEMVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEAYVKAKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYANSGGYSGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             20980..21867
                     /locus_tag="ctg4_53"
                     /transl_table=11
                     /translation="MKKLRTFAVSMVIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSR
                     MAGVKNREGAGLLADGKKTDEDSSTENSEKKRRKKQRRSSKSKNKNHADEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TESHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEIITPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             22059..23150
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_54"
                     /sec_met_domain="Peripla_BP_3 (E-value: 4.4e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
ORIGIN
        1 gaaacttcgg accggaaatt tccgaaacac ttcttgctaa acacttcgaa ggaccgaaga
       61 tgttctgtgc agcagctgaa gaaacacagg gcgacctgat ccagggacgt ggagatgcat
      121 actgcggtat gttaaatgca agctacaact tacagcttcg taatgtaaaa gcatatattc
      181 cggaatatcc ggttggtgat gcagaagact gcgcagatat gatccatgac ttccttccaa
      241 tcgcaagagc agttgaagga ttaagcaact taaagatcat cagctttgga ccacgtccaa
      301 caaacttcct tgcttgtaac gctccgatca aacagcttta caaccttggt gttgaaatcg
      361 aagagaactc tgaacttgat ctgttcgaag cattcaacaa acatgcagga gatgagagaa
      421 tcccggcagt tgttaaagaa atggaagaag aacttggtgc aggaaacaag aaacctgaaa
      481 ttcttgagaa acttgctcag tatgaactga ctctgaaaga ctgggtagag gctcacagag
      541 gatatcgtaa atatgtaaca ttaacaggaa aatgctggcc ggcattccag acacagtttg
      601 gatttgttcc ttgctatgta aacagccgtc tgactgctca gggcattccg gtatcctgtg
      661 aagttgatat ctatggtaca ttaagtgagt tcatcggaac tgttgtaagc caggatacag
      721 ttacactgct tgacatcaac aactctgtac cgaaggatat gtacaaagag tctatcgaag
      781 gcaaatataa ctacacactg aaagatacat ttatgggatt ccattgtgga aatacagctt
      841 ccagcaagct ttccttctgt gagatgaaga accagatgat catggcaaga tctcttccgg
      901 tagaggttac aaacggaact cttgaaggag atatcgtacc tggagatatc acattctatc
      961 gtctgcagag cacagctgat aacaaactcc gtggatatat tgcacatggt gaagttcttc
     1021 ctgttgcaac gaaatccttt ggttctatcg gtgtattcgc tattccggaa atgggacgtt
     1081 tctaccgtca tgtactgatc gagggaggat acccacatca cggagcagta gcattcggac
     1141 attatggaaa agctctgttt gaagtattca aatacatcgg tgttccggtt gaagagattg
     1201 gatacaacca gccggcaggc gtaagatacc caacagagaa tccatggggc taatcagaat
     1261 tcaacagtat tgaatcaaga ttgaaaaaat aatagactga cacgacaatt tataaggcat
     1321 cccgggggtt taccctggga tgtattagat taaatgagtg tgagaaatta acttcaataa
     1381 aaatctgaat gaacttcata tgaaagatac gaagatataa ttgcctggta agagcaatct
     1441 ggcgatttat ttcagataaa cgaacagcaa tgaaatgcag taatgcaata aagactaata
     1501 ggagagaaaa ttatgtatta tattggtatt gaccttggta cttccgctgt aaaacttctt
     1561 cttatggaag attcaggaaa aatctgtaat attgtttcaa aagaatatcc tttattcttc
     1621 ccacatccgg gctggtctga acagaaaccg gaagactggt ttgcacagag catggaaggt
     1681 atgaaagaac tgacaaagga tattgacaga actcaggtag caggaattgg tttcggcggt
     1741 cagatgcatg gtctggtaac tctggacaaa gatgacaatg taatccgtcc tgcaattctc
     1801 tggaatgatg gtcgtacagg cgaggaaaca gagtatctga atactgtgat cggaaaagag
     1861 aaactctctg agtatacagc aaatattgct tttgcaggat ttacagcacc gaagattctc
     1921 tggatgcaga aaaatgagcc ggagaatttc aagaaagtag ttaaaattat gctgccgaaa
     1981 gattacctgg catatcgtct gtctggttct ttctgcacag atgtttccga tgcttccggt
     2041 atgcttctgc ttgatgtaaa gaaccgttgc tggtcaaagg aaatgctgga aatctgcggt
     2101 atcacagaag agcagcttcc gaaactgtat gagagctggg aagtagtagg aactctgaaa
     2161 cctgaaattg caaaagaact tggattctca gaagatgtaa aagttgttgc aggtgccgga
     2221 gataacgcgg cagcagctgt tggaacaggt acagttggtg acggacagtg caatatttct
     2281 cttggaacat ccggaactgt atttatttcc agcaagaatt ttggcgtaga cgaaaataac
     2341 gcacttcatt ctttctgtca tgcagatgga agctatcatc tgatgggatg catgctcagc
     2401 gcagcttcct gtaacaaatg gtgggcagag gagattcttc agacaaagga tttcgcagca
     2461 gagcaggctc caattcagaa gctgggagag aatcatgtat tcttccttcc atatctgatg
     2521 ggagaacgtt cacctcataa taatcctgat gcaagaggtg tattcttcgg aatgtccatg
     2581 gacagcacaa gagcagacat gacacaggct gttctggaag gtgttgcctt tggtcttcgt
     2641 gattccctgg aggttgcaag aagccttgga atcaagattg agagaaccaa gatctgtggt
     2701 ggcggagcta agagtctgct gtggaagaag atcattgcaa acgttatgaa cctgaaggtt
     2761 gatgttctgg agaacgaaga aggaccgtcc atgggtggag ctatgctggc agcagtgggc
     2821 tgcggtgctt atccggatgt agaaaccatc ggaaagaaat ttgccaaagt tgttgataca
     2881 gtagaaccgg atcctgaact ggttgcaaaa tatgaagaga gatatcagaa gttcagaact
     2941 ctgtatccgg ctatgaagcc actgttctaa tcgaatatct gcctgacata ctggggttgt
     3001 tgtgcttatt tagcacaaca accccatttt gacgtacatc tgatgatgac caatcaccat
     3061 agcctgtttg attatggcat atcaggaaaa gggcagcttg aggaattctt tcatggctct
     3121 gctgatatag cggcctttct tccagtaaaa aaatacagtg cgtttactgc tctgaccggg
     3181 cagcttataa aaaataagtt ctgaatttgt tggaactctg gagagcagca gatccccgat
     3241 gaaagtgata cccattccca aacatgcaat attataggca gtcatctgct gatccaggcg
     3301 aaataccaca gaaggtgaaa agtgattttc ctgacaaatg gtcagtgcac gcttaccggt
     3361 atcgttatct gaacgaagaa taataaatgg ttcgttctcg aatttgttta atggaacaga
     3421 aggaatatga gaagaacgga actgcccgtt ccggatttcc ccaataggaa tctgatattc
     3481 ctgcagtctg gtattgattg aataattttt gggaaccgct agaagaagtt gttctttctg
     3541 gtagatataa tgttcaaaaa tctggttatc cagaatacag ttatcgatta ccagatctaa
     3601 ctttccggcc tggagaaact gggatagctt tgctgtactt tcttctacaa gagaaatttg
     3661 aacatggggg aatttttggg aaaaatcagc aataagggga ggcagaatcc acgaagaaaa
     3721 aaagttactg ccacctacat tgagagttcc tgttttgaga tttccaagat ctaataggaa
     3781 attttcaaga ttattttcaa tatccatgac tttttcaaca gcctctatat aatgttttcc
     3841 aacttcggtt aactgcaaag gtttggtact tcgatcaaaa ataggataac caatgcggtt
     3901 ttccacacgt tttacatttg cacttaaaga aggctgcgaa atgaaaaggg cagcagcagc
     3961 tttggaaaag cttttttcct tgtatacttc ataaatatat tccattccct gaaacatatg
     4021 atccctccaa tatataattt agttactgtt cactctgttc atagtaacat aatttaaaca
     4081 ctatatattt tataaaaata tatgtatttg attatattat agcagagata tataataagg
     4141 gcaaatacat gggagggcga ataactatga aaaaaataga ctatcgtgta gaaagggatt
     4201 ctattggtgt aaaggatatt ccggaagatg tatattatgg agtacaatcc ttacgtgcgg
     4261 ctgaaaattt tcacattacg gggctgaata tgcatccgga aattattaac agtcttgcat
     4321 acataaaaaa agcagcagcg ataactaatt gtgaagtggg gcttcttgag aagaaaaaag
     4381 cacaggcgat tgtccaggca tgtgatgaaa ttgtttcagg aaaattccat aatgaattta
     4441 ttgtggatcc tgttcaggga ggagcaggca catctttaaa tatgaatgcc aatgaagtaa
     4501 ttgcaaatcg cgcaattgag atactgggag gaaaaaaggg cgattataca attataaatc
     4561 ctaacgatga tgtgaattgt ggacagtcta ccaatgacgt tattcctact gccggtaaaa
     4621 tgacttctct tcgtctgctg cagaatctga agaaacagct tcttcgtctc tacgatgctc
     4681 ttaacgaaaa agcggtagag tttgatcacg taatcaaaat gggacgtaca cagatgcagg
     4741 atgcagtgcc gattcgtctg ggacaggaat ttaaggcata ttcggtagca atcatgcgtg
     4801 atatccacag aatggataaa gcaatggatg agatgcggac ccttaatatg ggaggcactg
     4861 ctattggaac aggaattaat gcagatgagg gttatctgag aagaattgtt ccaaatctta
     4921 ctgaaatatc aggaatggac tttatacagg cctttgatct gattgattcc actcagaatc
     4981 tggatccatt tgtagctgtt tccggtgctg tgaaagcatg tgcggtaact ctttccaaaa
     5041 tgtcaaatga tctccgcctg atgtcctctg gtcctcgtac cggatttgga gaaatcaatc
     5101 ttccggcaaa acagaatggc tcctctataa tgccgggtaa agtcaatccg gttattcctg
     5161 aagtagtgaa tcaggtggct tttaatatta ttggtaatga tgttacgatt actatggctg
     5221 cagaggctgg tcagctggaa ttaaatgctt ttgagccgat tattttctat tgcatgtttc
     5281 agtctatcga tactcttggc tatgcagtcc agacattggt agataattgt attgtaggaa
     5341 ttacggcaaa tgaagaaaga tgccgttatc tggtagaaaa cagtgtaggt attatcactg
     5401 cgatcagccc ccatcttggg tatcagaagg ctgcggatat tgcaaaaaag gcaattaaga
     5461 caggcgaatc tgtaagaagt ctgattctga aagaaaagct tatggatgag gatgaactca
     5521 atcgtattct ggatccgatc catatgacgg aacctggtat ttccggaaaa gattatctta
     5581 taaaaaaata aagaaaaaaa caggcgggaa aatcttcccg cctgtaaaat cgtctggaca
     5641 catatcatat ataaatatga tttttatatt tttgaattat tcgattgatt tcaaccggat
     5701 tagaacagac ctgtgatctt acctgtctcg tctacgtcga ttctctcagc agccggaacc
     5761 ttaggaaggc ctggcattgt catgatctca cctgtaagag ctacgatgaa tcctgcacct
     5821 gcggaaatct tcaggttacg tactgtaact tcaaagtctg taggagcacc cagtttggtc
     5881 tggtcatctg ttaagctgta ctgtgtctta gctacacaga tcgggcagtt gccgaagcca
     5941 agagcttcta actgtttcgc ctgtttctga gcatttgctg tcagaacaac tctcttgccg
     6001 ccataaactt tctgaacaat ctggttcagt ttgtcttcga tagaaccttc cagttcatat
     6061 gcataggaga agtcgtttgg ttcttctaca agacggataa cttcttctgc aagtttgatt
     6121 ccgccttcgc cgccttttgc ccatacttca gaaagagcaa cgttaacgcc cagttcttta
     6181 catttagctt ctacaaagtc aagctctgct tttgtatctg tagggaatgc gttgatagca
     6241 acaacacatg gaagtttgta tacgtttttg atgttggaaa cgtgttttaa caggttcggg
     6301 ataccttttt caagagcttc caggttttca ttgttgaggt cagcttttgc aacgccaccg
     6361 ttgtatttca gggcacgtac tgtagctacg attacaactg cgcttggttt taaaccagcc
     6421 atacggcatt tgatatcaag gaatttctca gcaccaaggt cagcaccgaa accagcttct
     6481 gtgattgcat aatcagcaag cttcatagcc atctttgtag ctgttacaga gttacatcca
     6541 tgagcgatgt ttgcgaatgg tccgccatgt acgattgcag gaacgtgttc cagagtctgt
     6601 acaaggtttg gtttcagagc atcttttaac agagctgtca tagcgccttc tgcgtgaagg
     6661 tcaccggctg ttaccggttt ctgctcggaa actttaccat atgtataacc gatgatgatc
     6721 ttggataatc tttctttcag gtctttgatg tcacttgcga ggcaaagaac tgccatgatc
     6781 tcagatgcaa ctgtgatgtc gtatccgtct tcacgaggca taccgtttgt tcttccgcca
     6841 aggccgtcta ctacgttacg aagctgacgg tcgttcatat ccacacatct tctccatgtg
     6901 atcttacgtg ggtcaatgtt taatgcgttg ccctggaaga tatggttatc gatcatagct
     6961 gccagtaagt tgttagctgc gccgattgca tggaagtcac ctgtgaagtg aaggttgatg
     7021 tcttccatag gaacaacctg tgcatatccg ccgcctgctg caccgccttt aacaccgaat
     7081 accggtccta aggatggctc acgaagagct accataacac tcttgccaag tctctgcata
     7141 ccatctgcaa gacctacagt agtagtagtt ttaccttctc ctgcaggagt tgggttgata
     7201 gctgtaacga ggattaattt tccgtccttc ttatcgcttt ctttcagaag attgtagtcg
     7261 atttttgctt tgtattttcc gtactgctcc agatatttgt cgtcaatacc tgctttttct
     7321 gcaatctgag taattggaag catctcgcat tcctgtgcaa tttcaatgtc tgatttgaat
     7381 cccataattg tttttctcct ttcgtttccg cataacatga aaaacttctg ttgctgttca
     7441 ctccgcgatc agcaacaatt attaattgaa agaagtattg gccggtctgc ctggtattcc
     7501 tgatttctgc cctgaaagtt ataaaaaaag gccagtatct gaatatttca aatactgccc
     7561 agacggtcgg ctcccacaaa cctccgactc cacgtggttt gcactccact ctttccgtca
     7621 gtactcgaag gttctttcaa ttgatgaata caatatatca ttttgagaaa aaaatgtcaa
     7681 gaaaattttt gctgaaacgt caaaaaatgt gagtaaactg gataaaagtt gtgcaaattg
     7741 ataagagaag agaatcgtaa tccctggtaa tgaaagaaaa tacgttttct caaggaaaga
     7801 aattgttaaa aaatagacac agttttccct gataaatgaa gaaaatataa aaagcgggta
     7861 aagactgtgc aaaatatgga aaatggaatt gacaacagtt cagaagatat gttattctca
     7921 tctttagtat gaaaagacac tatcgttttc atgcaaatat ttgctcacat tcagagacag
     7981 tttctgaatg ttaagccata cggacaggcg gggcagttgc cgggtgggag acaccacatt
     8041 attgattgag ttagaagctc aaattttata agttgattac tttataataa tcagtgcgta
     8101 agcacacatc atcttgtgaa acggtcaata agagcatagc atatatttgc cagcgattga
     8161 agacgacagc agtcatgaat atttcagaat acgggaacag gcacaggata cagacggatt
     8221 tatacgggaa atccggtcag tatataaaga gacagagcct gagaaattct atagatcatg
     8281 agagaagcag atggtgaatg aacttatctg cttctttttt tgtgcagata tagcaaatat
     8341 aaaggatatg gttggagata aacgctttgc ggggatgtgt agcgattcta tagaatcgtg
     8401 tgccgagtct cacatgcgtt cgacttgaat atatagagaa ataattgaat cattgtgccg
     8461 gttttgagcc agtatacaat tgctgtatga ttgaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccggagctt gcacagcttc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc atccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcgc atgcatttct gatggtagga ggaaccacat
     8821 ctgcagtgca gagtatgatc ctttctgtct gtaaggcagg ggacaagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg cggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgcg cagctgggca tttcccttgg catggaagtc agtcaggtgg
     9001 agaaggctat ggatgagaat ccggatgcgg tggcagttct tgtaaataac cctacctatt
     9061 atggaatctg ttcggatctg cggactatcg taaagaaggc tcatgcaaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtatccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agtgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcactcagg ggagaggaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gttattatgc atatggtatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc catttataca ctgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccatcgg agacaggctt caggatattg
     9661 agagactggt aggggcattg gctgatattg aacgtctgta taagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagtggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctgggga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaacg tcttcaggtc ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtattct ctgacaagga tgaatttatt tatgatgaaa tggtcacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg atcatcggcg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtggaatc
    10321 tgataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggtggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaacagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaaggtagat
    11041 gcggataatg cagcagaggt cgcagaattg atcagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctacgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgagaaatt taaggaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgcc tatgccctga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaacggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct acgatttccc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa aaatattccg
    11641 ggagtacaga ggatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaatgg acaggagatc
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttcag gctttgccct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatagag gaactggatc gtatctgtga
    12421 ccatattatc tttaattcca cagcacagct gaagaaattt aaagatgtgt gtaccagagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg caatctatga
    12541 tccctgtgcg ccgggttcca ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatc gacggactgc atttccatac gctctgcgaa cagaatgcag atgacctgga
    12661 gaaaacattg caggcagtag aggagaagtt tggagaattt ctgtctgagg tttcctggtt
    12721 gaatatgggc ggcggacatc acattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatggaat
    12901 cagaacgctg gttctggatg cttctgcagc ttgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgcctgg caggagatgt aatcggagat tattcctttg acagagagat
    13081 ccggatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcacaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agcttgggaa tgtttccggt gtgactttgc tggaatgcga gacagatgac gcctgggcca
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggaggt acctttgacg ggctttaccg gaactgggag aaggacgaca
    13681 gggtggctgc ctttatctgc aggactcttg gttgtccatg tctggatgcc agaccttttg
    13741 tgcttgaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtctct ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccgg gaagatgtgg atggctttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggctgcca gttatgtgaa tttctatatt tccaatggag
    14221 ggatcatcct tccacaattt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gttggcggtg
    14341 gaaatattca ctgtatcacc cagcagattc ccggaaaaaa tatctgaccc tgatgcagaa
    14401 aactttgaga gtcatgtgtt tgagggttat tacctgaaag ttatgaaaaa acttacttat
    14461 gtaaacagga gcaggaggaa cagacaggat gagaaatgta acagtggcag cagttcagat
    14521 gaaatgcagt aaaagtgtgg agaaaaatat tgcccatgca gaggaactgg tgcgtcaggc
    14581 agcagcaaag ggagctgaga ttgttcttct tccggagctt tttgaacggc cctatttctg
    14641 ccaggagcgc agatatgagt attatgaata tgcgcagact gtagaggaaa accctgcagt
    14701 gcgtcatttc agcagagtag cggcagagct ggggattgtg atcccggtca gcttttatga
    14761 aaaagaggtc aataatactt ataacagcgt tgcggttctg gatgcagatg ggaagaatct
    14821 cggcatttat cgaaaaacac atattccgga tgatcattat tatcaggaaa aattctattt
    14881 cacaccggga gacaccggct ttaaggtttt tgataccaga tttggaacca tcggagttgg
    14941 aatctgctgg gatcagtggt tcccggaaac agcaagatgt atggcgttgc agggagcaga
    15001 gcttctcttt tatcccactg ccatcggaag tgagcccatc ctggaatgtg acagcatgga
    15061 acactggaga agatgtatgc agggacacgc tgcctccaat ctgatccctg tgatcgctgc
    15121 caacagaatc ggtgaggaaa cagtagagcc atgtccggaa aacggaatgc agaaatctgc
    15181 tcttaatttt tacggttcct cttttattac agataacaca ggtgctctct gcgcagaact
    15241 gcccggaggg gaagaggggg tgcttgtaag cacttttgat ttggatgcat taaaggcaga
    15301 cagactgaac tggggacttt tcagagaccg cagaccggag atgtatgcaa aaattgtcgg
    15361 gaaatgacat acaagccaaa attccattgc cacaggcaat ctggaatgaa ttttggctca
    15421 gttactgaga acggagtgaa cagtaactga gtttataaga atttcataaa aagtttatga
    15481 ttatattagt tgctacctgt agtatatatg gtaaaataag agtacgaacg ttactgataa
    15541 cggagcagga aagttttgac atgtatttct ggcaaaatgg agtgtaaaag atgaacagaa
    15601 aagaattttt ggaaatcctg agaagccagc ttgccggtca gatgcaggag ggcaaagcag
    15661 cggcacatat caggtattat gaagattata tacagtctca ggtacgtggc ggacgttcag
    15721 agcaggaagt actgcaggaa ctgggagacc cacatctgat agcaaagact ctgattgata
    15781 cagatgatgg aagtacacag gaagattacg gagagtattc ttcttacgga agcagttatg
    15841 gcaatgagac agagtttcct catcagcagg agaaacgatg gaaaaaagta attgatcttt
    15901 ctacctggca tggcagggct gttgttattg cagcagcggc tgttataatt attttactga
    15961 tactgataat cggagttgcg attccgtttt ttattattct tgcaattatt ctttattttc
    16021 tttcatggct gaagaaaaga aataatcaat gaaaatctat gcagggtttc agaaaagaaa
    16081 ccctgcgcaa aatcttaaaa attttaaaaa tctaaaaaat cttaagtgta aacattcttg
    16141 tttcacgata ttaattcccc ttgaatattt ataatcatat aatttcaact tatttctatt
    16201 ctttaatcct gccttgtgca gggaaaaatc ccacattcat ttttatattt tttgttcgga
    16261 aaggagacgg aaaatgaaac acaatttcaa actgaaagaa cgccttggag ctttgctgct
    16321 tgcaatgctt tttattctgc aggcaattct ggggcttgtg cctgtctgtg taactcaggc
    16381 ggcaccgtta actgtagaaa catgggacag tgacaaggtg gtagattatg gttatcgctt
    16441 taacatgaag tttcagcccg gaattaccac atatgaatct tttgggtgtg ataatctgga
    16501 cagggaagct ttttcagaca atggaaaaag cgaacgtgac acagagtgcg ttcgtgtagg
    16561 agcggactat aaagccggaa gcgcagggat gcgttataac aatgtaggaa aagatggaaa
    16621 tggaaatatt gttgatgtca gactcattct tgtgggagta gagaatgcag aacctcgtta
    16681 tgatctgcgc actgcagaat cgattgttca gaataaaggc ggagctacgt ttgcatggaa
    16741 agataatgaa gcttatccaa tggttggctt ttccaaaaac agtatcggtg tatttattta
    16801 ttctgtagga tacgcaaagg ttaagtttca gtttctgaag catggaacag aagaaacact
    16861 gccgatcagt ggccatggaa ccatacgtga tattgatgcg ggacagggag tccgtattcc
    16921 atcagacagc agtctggata atgcatatgt tctgaaaaac aatgattatc tgacggtaga
    16981 tgggaattct gtaagctcac cccttggttc cgttgagccg gatgatccga gaggatggct
    17041 gaatcttttt tataatacag ataattttac ggtagaattc tgtcatcagt tcagactgga
    17101 taaatgggat aaaagtcgtg aagatgctat tgcaaaagct ggttctcagg aaagatgggc
    17161 agagattaca agaaataaat atctggatcc atcaggcaac agttattgtc cgaactttaa
    17221 aggacagaaa tactgcaaag catatgcata ttttgatttt acatcctatt gtttcggtga
    17281 tgttgagatg aaaaaagcgc ctgagaaacg tgtgggagag gcaaactgta catgggaaca
    17341 ggcagctgcc gcatcaaaag aaaaaccttt tagcattcgt cagggacagg aatttcagta
    17401 tatgatccgg gcagaggtga cacccaatag actgaaatcc tttgtggtac aggatatact
    17461 tgaggattgt cttactatag aggatgcatc aaaagtcagt attgtgaatg atgtagggca
    17521 gacagtgaca gactggtttg atgttgctgt tgaaggacag aaagtgacct gcagggccaa
    17581 agcagagagc cttcaggatg aagcatttac agataatcag acttacacat ttactttaaa
    17641 agtacgccag aggccggaat cagaaattaa catttcaaaa taccttgcag aggatggata
    17701 cagtattctt gtaccaaacc atgcatccat gagttatgaa cgtacaaacg gaagcggaga
    17761 tacaatggat acggaaacag tgtgggtaaa gggtgtgatt ccaccggaac tggaagtaaa
    17821 gaaaaatact tctcagtatg aatggaaaac gggagatatc atagattatg aggttctggt
    17881 ttctcagaca aaacaggatg taaaagcagt aaatgttgtt attacagacg agcttccatc
    17941 atgtctgcag cttctggaag ggcagtatgc tgtagagaca agtcagggag gcgagaactg
    18001 tacgcttacc ggacagggag aaaatggatg gaaagcagag tgtccgtccc tgaagtatgg
    18061 ggagacgatc acaatccgtt ttaaatgtca ggcatctgcg gattccaatg gacaggaatg
    18121 ggaaaatatt gtgactgcaa cagcggataa tctgatcaat cctgagacag gagaacagga
    18181 atctagaaag gatatggcag aagtatggcc gaacagtcca cagcttgaaa ttgataaaac
    18241 agcagacaaa tatgaatggc aggcaggaga gcaggtagct taccggatcg tggtgaataa
    18301 tgtaacggca ggaacaatcg caaaagatgt aactattact gatattggtt tgccgcaggg
    18361 actggttctg gcaggtggtg cacagagcat ggaagtactg ggagttcagc aacaggtaaa
    18421 ctatcccgta ccggataaga aaacaggaca ggcatatgaa gcgagacctg tggattctca
    18481 gttgaatgca gatgagaacg gattttcctt ttattgttct tatgtaccat acagtcagcc
    18541 tgtaacgatt attttccatt gtatcgcaca ggaggaggca aatggacacg aaagcgtaaa
    18601 tgcagcaact gtaaaagctg ctaatacaga tgagaaatct gatgatgcag aagtatatgt
    18661 aaattcagga gaattctgga ttgagaaatc tgcagatcat tatgaatggc aggtcggaga
    18721 acaggtacag tacaatgtgg tggtggagaa taaaaaagca ggtacagtgg cccggaacgt
    18781 aactgtctgg gataccggta tgccggcagg acttgcgctt tcatcggcaa aggatgtatc
    18841 ggtaagcgga atcccacaga atattacgca gctgacagca gggaccaaag atgttttgaa
    18901 ccagctcaat ccggaatttt ataatgagac atcagagaaa ccagtgaatt atgaatttct
    18961 tcaggaggga agcggatgga gactgaacat ttcagatctt ccggcaaata ctccggttat
    19021 gatttctttc ctttgcacag ttacggaagc ggcaaatgga atggaaagca ttaatgttgc
    19081 caatgtgcag gcgcagaatg cccctgtttc acaggatgac gcagaagtgt atgtaaatac
    19141 agcagttctt tctattgaga aaagttttca gaatccatat ctggcagccg gggacggacg
    19201 tgcggaaaat gaatttcggg taggagaaca ggtgaattat caggttacgg ttaataatct
    19261 tcagaaggga tctatcgcaa gaaatcttgt gatcagtgat ctttcccttc ctgaagggct
    19321 ggctctggac ggagctgaag atgctgttac tgtaagcggt gttccggctg ttattcagaa
    19381 tccggtggca ggaactgatg atgcaggaaa tcagctgaat ccggaaaatt ataaagaaac
    19441 agtggaaaaa ccggtcagct gtcaggttac acgtcaggga actggttgga tcgtgacgat
    19501 ttcagatctt ccgtatcaga cacctgtgac tgttaatttc cgctgtactg cgcaggaaag
    19561 cgtaaatggg atggagattg taaatacagc acaggcatat gcagataatg cacagaaagt
    19621 aaaggactcc tcaaaaatct gggtgaactc gcctgttcta aaagtagaga agacgacgga
    19681 caaaccattt tacaaatatg gtgatattat tacataccgc attgtcctga cacaggagca
    19741 gaccggatgt gtggcgcgta atgttactct gcaggatgtg atcgatactc agggagtacg
    19801 tcttctgaaa gattcggtga ttctgatgga tgagaaagga aatgtggcag atgctgatgt
    19861 acagatcaat gatgataata ctttcctgat gtcaacaggc aggacactgg tcagggatag
    19921 cagatatagt atctgcgata atgataaagg cggtcttttt gagcaggtaa tgtataatcc
    19981 tctggactgt caggaacaga aaagtatgat cgtggaatat caggcagcgg tgattgatgc
    20041 agccctggca ggacagaaag tgcacaatac tgcagttgca gacagcagtg aaaagatacc
    20101 tgcaaccggg gaaacagaga cagaggtaca cagtccgatt ctggaaattg tgaaggaatc
    20161 agataagaaa gagtatgcgt ccggtgagaa aggatactat aaactgacag taagacaact
    20221 gcgtgaggat gtcacagatc agaatattgt tatcgaagat aaattggaaa cccaaggggc
    20281 ttccattgta aaagacagca tttttgtgaa gaaaaacggt atagaactga aagatgccaa
    20341 aatagaggca gatgatacag gatttgtaat tcagacagga gcatcgttgt cagatatgga
    20401 taaaattgaa gtctgctatg aaatggtatt taaaacagaa agcacagagc ctgaaaaaat
    20461 tgtaaacaca gcgaaagcaa gaggtgatat ttcaccggaa attactgcac agcaggaggc
    20521 atatgtgaaa gcaaaagcag aaccgactgc cacaccaaca ccgtctgcaa caccgaaacc
    20581 aacagaaaca ccaaagccga cagagacacc aaaacctaca gaagtaccga aaccgacaga
    20641 gcagccaaaa gccacaccaa caccatctgt accgggaacc tgcccgaaaa tgactcctgt
    20701 accgacgaaa gcaccgttag catcttataa tggtggaaat aatggaggca caacttccgg
    20761 aagcggaggc agcagttacg caaattcggg tggatattcc ggtggatacg gaagctatca
    20821 gggtggttcc atggcaggaa gttctaaaac aggagatgtc agaccgttta aaatgatggc
    20881 tgttcttgga ctcatcggaa tgggactgct gacaggaggt gtggtgatct acagaagaac
    20941 tgtttccggg aaaagaaata taaagggtat gccgcggaaa tgaaaaaact cagaacattt
    21001 gcagtaagta tggtcatagc agcaattggg cttcttatat attgtgccgg cttctatata
    21061 aaaagttatg aacagaatct tgcagcaagg caggaatatg cagagctttc ccgaatggca
    21121 ggggtgaaga acagagaagg tgccggatta ttggcagatg gcaaaaaaac tgatgaagac
    21181 agcagtacag aaaacagtga aaaaaaacgc aggaaaaaac agagaagatc ttctaaatca
    21241 aaaaacaaaa accatgcaga tgaaatcagg gaatccttcg ggatttcctg ggaaaattta
    21301 agaaaaatca actctcagac agttgcctgg attactgttc cgggagccga tatttcttat
    21361 cctgtagttc aggcggcaga tgatgaatat tacctgaaac ataatttcag gggagaggaa
    21421 gatctgtttg gctgtatttt tctggaacat gacataaaaa agaactttac agaatcccac
    21481 agtattcttt acgggcacaa tatagaaggt aatatgatgt tcgcaaatct gaaccgttat
    21541 gaacagcctg aatttctgaa aaaatgtcct gaaattgaga tcataacacc aaaaagaaag
    21601 tttctgtaca aaattttttc tgtggaacag gcatcttccc aaagcccggc atttgaatat
    21661 ggatacaagt tatccagtcc tgcatacagg agacaattat ctatattgaa aaataattcc
    21721 atgtatgaca caggagtaga gcctgatgaa agggagagaa tggtgactct gatcacctgt
    21781 aattcacgtc tggataaaga aatacgtatg gcggtacatg ggatttgcca tgaatgttat
    21841 ggtatagaaa aagctgagcc gaagtgatgt tgaaatcaat cggatattgg taactttcgt
    21901 aaaggatgaa ctgttactgt tcacatatca ctatccctcg aggtgttttg gaaaaaacta
    21961 atgaaaaatc tctcgatatt ttgtataatt tatgcataaa aaacaacttg ttcgtacgtg
    22021 cgtacaagtt gtatcctaaa tacaggaggg aagaagacat gacagataat ggaaagccga
    22081 aatatttctc actgatggaa cagctcagaa gtgatattat gtcaggagct atccgaccgg
    22141 gagagaagct tccttcagaa aacgagcttt cacagaaata ttccctgagc agacatacgg
    22201 ttcgtaaggc actgggaatc ctggagcagg acggatatgt agaggcattt cacggaagag
    22261 gtacttattg ctctgagaat atgcgccata taaagaattc aaagaatatt gcggtagtga
    22321 ccacatatat ttctgattat atttttccga gactgataca gggaatggat aatgtccttt
    22381 cagaaagcgg ttacagtatt atcctgaaaa acacagcaaa cagcagacag aaagaggcca
    22441 gatgtctgga ggaacttctg aagaaagata ttgatggact gatcattgaa ccaagcaaaa
    22501 gtgagatgat ctgtaaacac agaaatcttt atcagaatct ggataaattt gaaattccgt
    22561 atgtgtttat tcagggaatc tattcagaaa tgagggataa acctcatatt cttatggatg
    22621 atgcacaggg aggctatctt gtaacaaaat atctgctgga actgggacat aaaaagatca
    22681 agggtttctt taaggcagac gatatgcagg gactggagcg ccacaaggga tatgtgaagg
    22741 ccttacagga gtcagggatt gcctatgatc ctgatgatgt tgtctggttt catacagagg
    22801 acaggaaagt aaaacctgca ctgatggcaa aagaaatggt acagagcgga cagcttccgg
    22861 atggaatcgt ctgttacaat gatcagattg ctgttcaggt tatggaagaa ctggagaaaa
    22921 tgggagtcag gataccggat gatatttcca ttaccggtta tgacaattca ctgtatgctc
    22981 agcgaggaag cggaatcaca acgatagctc atccgcagga aaagttggga gaaatggcag
    23041 cagagcttat acttgagaag atcaacggag ttcctgaaga agaaagtaag gttgaaagac
    23101 tgatttatcc ggaactgatc atacggggat catgcagaaa aatattgtaa acaaatgaaa
    23161 taaataaaaa ataaaaataa atccaggagg aattttatca tgaaaacagg aagaaactat
    23221 aagttttggt tttgtacagg ttcacagga
//
