LOCUS       c00086_gnlPro..        10976 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EDGALAIC_86.
ACCESSION   c00086_gnlPro..
VERSION     c00086_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 02:48:35
            Original ID  :: gnl|Prokka|EDGALAIC_86
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10976
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10976
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4268:8492](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(4269..8492)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..10976
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10976
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             89..1846
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg86_1"
                     /sec_met_domain="Transketolase_C (E-value: 2e-17, bitscore:
                     52.0, seeds: 80, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 1.1e-18, bitscore:
                     56.2, seeds: 81, tool: rule-based-clusters)"
                     /sec_met_domain="Transketolase_N (E-value: 6.3e-08,
                     bitscore: 20.5, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYLENIYSPADVKKLSFQELNDLSHEIRASLLQKLSAHGGHFGPN
                     FGMVEATIALHYVFNSPKDKIVYDVSHQSYVHKMLTGRKDAFLHPAEYDHVSGYSEPQE
                     SEHDFFVIGHTSTSVSLASGLAKGRDLTGGNENIIAVIGDGSLSGGEAFEGLDYVAELG
                     TNMIIIVNDNQMSIAENHGGLYKNLKDLRDSNGQCECNFFKAMGLDYMYVNDGNCVEAL
                     IEAFSKVKDIQHPIVVHINTLKGKGYEPAEQDKETYHWRTPFDLETGKSKMNDDAEDYS
                     EVTAQYLLKKMKEDKRVVTITSGTPAVLGFTPDRRQEAGKQFVDVGIAEEHAVALASGI
                     AANGGKPVYGVYSTFIQRSYDQLSQDLCINNNPAVLLVFWGTLSGMNDVTHLCFFDIPL
                     ISNIPNMVYLAPTCKEEYLAMLEWSIHQNEHPVAIRVPATDVISCGEPVESDYSNLNRY
                     KVAHRGSKVAILALGSFFGLGQSVLSLLKEKANIDATLINPRYITGVDSELMDELKADH
                     ELVITLEDGVLDGGFGEKIARYYGATDMKVLNYGAKKEFVDRYDIQELLRANHLTDEQI
                     VEDILSLIG"
     CDS             complement(1933..2823)
                     /locus_tag="ctg86_2"
                     /transl_table=11
                     /translation="MVKSRIFDNRQLLKEHPEIPHYKEEVVCFMSEYKDRSYPENERYF
                     NRELYMILVLEGRSEILLNGEFIVIEPDMLLVHGANYLTDHLYSSPDIKFITLSISESM
                     RTDDSYLTQITAILLATMRQNKQYTIQLTAYEAQIIRNELEVLMRLLNIKHQFLFRRIQ
                     AACNALFLDIADFLSRKTIIKKEVSRKDHVLQEFHALVTRNFREEHFVSFYADKLAISE
                     QYLARIVRAGTGKSVNTIINELLIMEARTLLSSTKSTVGDIASRLGFSDAAGFCKFFKR
                     NMGQTPLNYRKGLWI"
     CDS             2980..3651
                     /locus_tag="ctg86_3"
                     /transl_table=11
                     /translation="MGMKDVFKRYLVFVIGLYFLAAGIVLIVRSALGTTPISSINYVLS
                     LNSPLSLGTCTFLINMLLILGQFWVIRKNRTRQDTIEILLQLPFSFIFSAFIDFNMALT
                     SNLHPDNYGMSIALLLTGCMIQSIGVVLELKPKVAMMSAEAFVKYASRRYNKEFGKFKV
                     CFDVTLVTLAVILSLLLSQCIEGVREGSLIAACITGYIVSFLNQKIMTRKTLYKLLPVL
                     K"
     CDS             complement(3659..4282)
                     /locus_tag="ctg86_4"
                     /transl_table=11
                     /translation="MTTTNNNEDLEKKIIEAAKELFIENGFAETSMSDIAAKVGINRPA
                     LHYYFRTKDKMFQAVFGNIILSFIPKIHDIIIQQDKPVSESIGEIVDAYYKVFTENPCL
                     PLFMVREMHRDMNHLSDTIKELRLEQYLHKIMDVLQEEMNDGRLKTVPLPFVFYTFYSA
                     LTVPFLTKNLSASFFLEKDDSFEDILVQWKPYIVRQMETLLVVS"
     CDS             complement(4269..8492)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_5"
                     /sec_met_domain="HGD-D (E-value: 4e-29, bitscore: 91.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 7.3e-36, bitscore:
                     112.6, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIGIDVGSTTAKLVAVDENDNLLFSKYERHNAKAKETILSFLK
                     ELLSEIGDKDISVRITGSIGMGISEKCSLPFVQEVVAAAKAIQKDYSHVTSMIDIGGED
                     AKVVFFKDAEATDLRMNGNCAGGTGAFIDQMAIILGVNIDELNQLAMNATQVYPIASRC
                     GVFCKTDIQNLIAKNVSRENIAASIFRAVAVQTVVTLAHGCDITTPVLFCGGPLTFIPA
                     LRKAFIDYLSLDEKEIILPANGTLLPALGAALFHLDKEDYCKLSHLIDKIDTTLNGNGN
                     LASTGLEPVFASNEEYEAWKERISRHKMISSGLKAGTQDVFIGIDSGSTTTKIVVLDED
                     SRLLYSYYNINGGNPIKAVEEGLNQLNDECLKQNAVLNIKGSCSTGYGEDLIRSAFQLH
                     SGIIETIAHYMAAHYLNKDVSFILDIGGQDMKVIFVNNGVIDRMEINEACSSGCGSFLE
                     TFAKSLGYSAQEFSLAACHSEAPCDLGTRCTVFMNSKVKQVLREGATINDIAAGLAYSV
                     VKNCLYKVLKLKDISVLGKDIVVQGGTMRNDAVVRAIELLSGAEVARCDTPELMGAFGC
                     ALYAMKHQGESVSLDEIINKAQYSARSLYCKSCDNRCLVIRYEFESGKSYYSGNRCEKV
                     FTNGESSNRKGLNVYRQKEELLFHRSAEIAAPEQIIGIPRCLNMYEEYPFWHTLFTSCG
                     IQVCLSDPSNFRKYEHNARMVMSDNICFPAKLVHSHVQDLIEKKVDRIFMPFVIFERKG
                     MEQNSYNCPIVTGYSEVIKSVQSEGISVDSPAITFKDRNLLFKQCREYLSGLSVDDRTI
                     QQAFQKAESEQHSFINTLVDYNKNILQQTGKGETLTVMLAGRPYHTDSLIQHKVSDMLS
                     DMGVNVITDDLVRQMDIPTGDAHFVAQWAYTNRILKAAKWCATQGKNIQFVEMTSFGCG
                     PDAFLVDEVRDLLMRHNKSLTLLKLDDINNIGSMKLRVRSMIESLKLANADGTEGDVKD
                     FTTVPVYDKSYRDRKILVPYFTPFISPLIPAIMKVAGYDAENLPLSDNDSSEWGLKYAN
                     NEVCYPATLIVGDIIKALKSGKYDISKIAVAITQTGGQCRASNYISLIKKALVDAGYTD
                     IPVISISVGSDIDNDQPAFKVNWMKVVPITFHAVLYSDCIAKFYYASVVREKEAGASAK
                     LRDKYLQLAPEVILRRNIKGLNSLLQSAITEFNEVCRAVDTPKVGIVGEIFLKFNPFAQ
                     KEIIDWLIGRKIEVVPPILADFFMQGFVNRKVNTDSYIKNRQLPEFIYDWIYKFVKKQI
                     DKINETASKFRYFAPFNDIFEEAEGAKSVISLNAQFGEGWLLPAEIVSYARQGVNNVVS
                     LQPFGCIANHIVSRGVEKRIKSFYPDINLLSLDFDSGVSDVNITNRMLLFIDNLKNATM
                     NYDNN"
     CDS             complement(8612..10975)
                     /locus_tag="ctg86_6"
                     /transl_table=11
                     /translation="ATLRFSQGATSASVSPDGKQVAFIVRGDVFVTSTDYATTKQITNT
                     PAKEAGVSFAPDNRTLVYASERTGNWQLYTAKIARKEEANFPNATLIEEEVLLPSKTIE
                     RAYPQYSPDGKELAFIEDRNRLMVLNLKTKKVRQVTDGSTWYNTGGGFDYEWSPDGKWF
                     TLEFIGNRHDPYSDIGIVSAQGGTITNLTNSGYISGSPRWVLDGNAILFQTERYGMRAH
                     ASWGSQQDVMLVFLNQDAYDRYRLSKEDFELLKEFEKEQKKAKEKDGDKKKDGSKSKKE
                     KADKEGDKEDTEEDKADKKDIVVELSGIEDRIVRLTPNSSDLGSAILSKDGENLYYFSA
                     FEEGYDLWKINLREKDTKRLHKLNSGWSSLMLDKKGDIFLLGSRNMQKMDAKSDALKSI
                     SYQAEMKMDLAAEREAMFDHVYKQHQKRFYNLNMHGVDWDAMTAAYRKFLPHIDNNYDF
                     AELLSEWLGELNVSHTGGRYSPRGNGDVTSNLGLLFDWNYLGKGMQIAEIVEKGPFDHS
                     RTKVKAGCIIEKINGEEITPDKDITDLLNNKAGKKTLVSLYNPQNKERWEEVVKPVTSG
                     QLNGLLYKRWVKQRAEDVEKWSGGRLGYVHIQSMGDGSFRTVYSDILGKYNNCDGIVID
                     TRFNGGGRLHEDIEILFSGQKYFTQVVRGREACDMPSRRWNKPSIMLQCEANYSNAHGT
                     PWVYKHQNIGKLVGMPVPGTMTSVSWETLQDPSLVFGIPIIGYRLPDGSYLENTQLEPD
                     IKVANSPETVVKGEDTQLKMAVDELLKEIDSRKK"
ORIGIN
        1 gtaattcata tacaaacaga tttcaaatcc gtcagtatct ttgcagtgaa ataaaaatat
       61 aggtataaac ataaaaaaac aaattgatat gtatttagaa aatatttact ctcccgcaga
      121 cgtaaagaag ttatcgtttc aggaactgaa tgatttaagt catgaaatcc gtgcatcact
      181 cttacaaaaa ctgagtgcac acggtgggca cttcggccct aacttcggaa tggtagaagc
      241 aaccattgcc ctgcactatg ttttcaattc gccgaaagat aaaattgtat atgatgtgtc
      301 acatcagagt tatgtacata agatgctaac cggacgcaaa gatgcttttc tccatcctgc
      361 tgaatatgat catgtatccg gctactcaga accacaggaa agtgaacatg atttctttgt
      421 gatcggtcat acttctactt ctgtcagctt ggcaagcgga ctggcaaaag gacgtgacct
      481 gacaggcggc aacgaaaata tcatcgctgt aataggcgac ggttcactaa gcggaggcga
      541 agccttcgag ggactggact acgtagcaga gctcggtact aacatgatta ttattgtcaa
      601 tgacaatcag atgtccatcg ccgaaaatca cggaggctta tacaaaaatc tgaaagattt
      661 gcgcgacagt aacggtcaat gtgaatgcaa tttcttcaaa gcgatggggc tggactatat
      721 gtacgtgaat gacggcaact gtgtggaagc actgatcgag gctttctcca aagttaaaga
      781 tatacagcat ccgatagtag tccacatcaa tacattaaaa ggcaaaggtt acgaacctgc
      841 agaacaggac aaggagacct atcactggcg tactccgttt gatctagaaa ccggaaaatc
      901 aaaaatgaac gacgacgcag aagattatag tgaagtaacc gctcaatatc tgctgaaaaa
      961 gatgaaagaa gacaagcgtg tagttaccat tacttcgggc acccccgctg ttttgggctt
     1021 cactcccgac cgtcgtcagg aagcaggcaa gcagtttgta gatgtcggta ttgccgaaga
     1081 gcatgcagtg gcacttgctt ccggtatcgc agccaatggc ggaaaaccgg tttacggagt
     1141 gtacagcacc tttatacaac gttcttacga ccagctatcg caagacctct gcatcaataa
     1201 taatccggca gttctgttgg tattctgggg gacgttatcc ggtatgaatg atgtaactca
     1261 cctctgtttc ttcgatattc cacttatcag caatatcccc aatatggtct atctggcacc
     1321 tacctgtaag gaggaatatc tcgccatgct ggaatggagc atccaccaaa atgagcatcc
     1381 ggtagctatc cgtgtacctg ccacagatgt aatcagttgc ggtgaaccgg tggaatccga
     1441 ctatagcaat ctcaatcgtt ataaagtcgc ccaccgtggc tccaaagtag caatccttgc
     1501 attaggctcc ttcttcggat tagggcaatc ggttctgtca ctgctgaaag aaaaagccaa
     1561 cattgatgcc acccttatca atccccgcta catcacaggt gtggacagcg aactgatgga
     1621 cgaactgaaa gccgaccacg aattagtgat tacactggaa gacggagttc tggatggtgg
     1681 tttcggtgaa aagattgccc gttactatgg cgctacagat atgaaagtgc tcaactacgg
     1741 agctaaaaaa gaatttgtag accgttatga tatacaggaa ctgcttcgtg ccaaccatct
     1801 gacggatgaa cagatcgtag aagatatcct atcactcatt ggctgataag tcaaaaccag
     1861 ttcattatat atttcatgta ggttgatgta tccgttcgtt atgggatcac atcaacctac
     1921 attcattttc acttaaatcc ataatccctt ccgataattg agaggagtct gccccatatt
     1981 cctcttgaaa aacttacaga aaccggcagc atcactaaag ccaagccggg aagcaatatc
     2041 ccctaccgta gattttgtgg aactcagcaa ggtacgggct tccatgatca gtaactcatt
     2101 aataatcgta ttcacacttt ttcccgttcc ggcacgaacg atacgtgcaa ggtactgctc
     2161 actgatggcc aacttatccg catagaaact aacgaaatgc tcttctctga aatttcgggt
     2221 aacaagcgca tgaaattcct gtaaaacatg gtctttacga ctgacctcct tttttatgat
     2281 agtcttacgg gaaagaaaat cggctatatc caaaaacaag gcattgcaag ccgcctgtat
     2341 tcgccggaaa agaaactgat gttttatatt cagcaaacgc atcaacactt ccagttcatt
     2401 acgaatgatt tgagcttcgt atgcggtcag ctgtatggta tattgcttat tctgcctcat
     2461 cgttgccaac agaatagccg ttatctgggt aagataagag tcatctgtcc gcatggactc
     2521 ggaaatggag agggtgataa acttaatatc cggactcgaa taaagatgat cggtgagata
     2581 attcgctcca tgaacaagca acatatcagg ctctatcaca ataaattccc cattcagcaa
     2641 aatctcggaa cgaccttcaa gaacgagtat catataaagt tcacgattaa agtaacgttc
     2701 gttttccgga tagctcctgt ccttatattc actcataaag cagactactt cctctttata
     2761 atgaggaatt tccggatgtt cctttaacaa ctgcctatta tcaaaaatac gagattttac
     2821 catttatacc tccttctttt cgacgtaaaa atacaatttg tttcggatat gacaaaaact
     2881 gtgtggaatc ggataactta tatcagacga aaaaacggga cctttgcata ttcttcttta
     2941 tagaatgaag aaaaatacga ttatataaga tagtaagata tgggaatgaa agacgttttt
     3001 aaaaggtatt tggtatttgt tatcggattg tattttctgg ctgccggaat agtgttgatt
     3061 gtgcgttctg cattaggaac cacacctata tccagcatca attatgtgtt aagcctgaac
     3121 agccctttat cattaggaac ttgtacgttt ctgatcaata tgctgcttat cctgggacag
     3181 ttctgggtca tcagaaaaaa taggacccga caggacacca ttgaaatact ccttcaattg
     3241 ccgttctctt ttatcttttc ggcattcatt gattttaata tggcgctcac cagtaatctg
     3301 catcccgaca attacgggat gtcaatagcc ttattactca caggatgcat gatacaatcc
     3361 ataggagtcg tactcgaact caaacccaaa gtagcaatga tgagcgcaga ggcttttgta
     3421 aaatacgcct cccgccgtta taacaaagag tttggaaagt tcaaagtctg ttttgatgtt
     3481 acgctggtca ctctggcagt catactctct ctcctgcttt cacaatgcat cgaaggtgtt
     3541 cgcgaggggt ctcttatcgc cgcctgcatc accggatata tcgtcagctt cctgaatcag
     3601 aaaataatga caaggaagac tctctacaaa ttattacctg tattgaaata agttttctct
     3661 agctcactac cagcaacgtt tccatctgcc tgacgatata aggtttccac tgaaccagaa
     3721 tatcctcaaa agaatcatcc ttctccaaaa agaaagaagc actgagattc tttgtcagga
     3781 aaggaactgt caatgcacta taaaaagtat agaatacgaa tggcaaagga actgttttca
     3841 gtctcccgtc attcatttct tcctgtaaaa catccatgat tttatggaga tattgttcca
     3901 ggcgcaactc cttgatagta tcgcttaaat gattcatatc acgatgcatc tccctcacca
     3961 tgaacaatgg caaacatgga ttttccgtga atactttata ataagcatct acaatttcac
     4021 cgatactctc ggagacaggt ttgtcctgct gaatgattat atcatgtatt ttgggaataa
     4081 aagaaagtat gatgttacca aaaacggcct gaaacatctt atccttcgtc cggaaataat
     4141 agtgaagtgc cggtctgttg atacctactt tagcagcgat atcactcata ctggtttctg
     4201 cgaacccatt ctctataaat agttctttgg cagcctcaat tatctttttc tccaaatctt
     4261 cattattatt agttgttgtc ataattcatt gtcgcatttt tcagattatc aataaacaaa
     4321 agcatacggt ttgttatgtt tacgtcgctc acaccactat caaagtctaa agatagcaaa
     4381 tttatatccg gatagaaact ttttatacgt ttttcgactc ctctggatac gatatgattc
     4441 gctatgcagc caaaaggttg caaactcact acattgttca ccccttgccg ggcgtaagac
     4501 acgatttcag ccggcaacaa ccagccttca ccgaattggg cattcagcga aataacgctt
     4561 ttagctcctt ccgcttcttc aaagatatca ttgaaggggg caaagtaacg gaacttactt
     4621 gctgtctcat ttattttatc aatctgtttc tttacaaact tgtagatcca gtcgtaaata
     4681 aactcaggca actgtctgtt ttttatgtaa gaatccgtat tgactttcct gttcacaaac
     4741 ccctgcatga aaaagtcagc cagaatcggc ggaaccactt ctatcttgcg gcctatcagc
     4801 caatcaatga tctctttttg tgcgaaagga ttgaatttca agaagatttc tcctacaatt
     4861 ccgactttag gagtatctac agccctacac acctcattaa attcagtgat tgccgattgc
     4921 aacaaagagt tcaacccctt tatgtttctt ctcagtatca cttcaggtgc cagttgcagg
     4981 tatttatcac gcagctttgc cgatgcacct gcttctttct cacgtaccac agacgcataa
     5041 taaaacttag caatgcaatc actatacaaa acggcatgaa aagttatcgg tactactttc
     5101 atccagttga ccttgaacgc gggctggtca ttatctatgt cactgcccac agagatagag
     5161 attaccggaa tatccgtata tccggcatcc accaacgcct tttttatcaa ggaaatatag
     5221 ttgctggcac ggcattgtcc tcccgtttgg gtgatggcta cggctatttt tgaaatatca
     5281 tatttcccgc ttttaagtgc ttttataata tcgccgacta tcagagtagc cggataacag
     5341 acctcattat tcgcatactt cagcccccat tcacttgaat cattatcact gagaggaagg
     5401 ttttccgcat cataaccggc tactttcata atagcaggaa tcaaaggtga aatgaacgga
     5461 gtaaagtaag gaaccagtat cttacggtca cggtaagact tgtcatagac aggaacggtc
     5521 gtaaagtcct ttacatcgcc ttccgttcca tccgcattcg caagtttgag gctttcaatc
     5581 atggaacgta ctctcaactt cattgaaccg atattattga tatcatccag tttcaataaa
     5641 gtcagcgatt tgttatgacg catcagcaaa tcccttactt catccaccag aaaagcatcc
     5701 ggtccacatc cgaacgaagt catctctaca aactgaatat tctttccttg tgtcgcacac
     5761 catttcgcag ccttcaggat acggttcgta tacgcccatt gagcaacaaa atgcgcatca
     5821 cccgtcggta tatccatctg acgcaccaaa tcatccgtta tcacattcac tcccatatcc
     5881 gaaagcatat ccgagacttt gtgctgtatc agagaatcgg tatgataagg acgtccggca
     5941 agcatgacag tcagagtctc tccctttcca gtctgctgca atatgttttt gttataatcg
     6001 accaatgtat taataaaaga gtgctgttcg ctttccgctt tttggaatgc ttgctgaatc
     6061 gtccgatcgt ccacgctcaa accgctcaga tattcacggc attgtttaaa caacagattc
     6121 cggtctttga aagttattgc aggggaatca accgatatac cttcggactg cacacttttg
     6181 ataacctccg aataacctgt cacaatcgga caattataac tgttttgttc catccctttt
     6241 ctttcgaaaa taacaaaagg cataaaaatc cggtcgacct tcttttctat caagtcctga
     6301 acatgactat gtaccagctt agccggaaag cagatattgt ccgacatcac catacgcgca
     6361 ttgtgctcat actttctgaa attggacgga tcagacaaac agacttgtat gccacaggaa
     6421 gtgaaaagag tgtgccagaa tggatattcc tcgtacatat tcagacatcg ggggattccg
     6481 ataatctgct cgggtgctgc aatctctgcg ctgcgatgaa acaaaagctc ttctttttgc
     6541 cgatagacat tcagaccttt ccggttactg ctctctccat tcgtgaaaac tttctcgcac
     6601 ctgtttcccg aataataact tttgccgctt tcgaactcgt aacgaatgac cagacaacga
     6661 ttatcgcaac tcttgcaata taaagaacgt gccgaatatt gagctttatt gataatctca
     6721 tccaatgata cggactcccc ctgatgtttc atcgcatata atgcacatcc gaatgctccc
     6781 atcaattcgg gtgtatcaca ccttgccact tccgctcccg agagaagttc aatggcacgg
     6841 accaccgcat cattgcgcat ggtgcctccc tgcacaacaa tatcttttcc caaaacagat
     6901 atatctttca gtttcaacac cttatacagg caattcttga caacggaata tgccagtccg
     6961 gcggcaatat cattgatcgt tgccccctcc ctgagtacct gtttcacttt tgagttcata
     7021 aaaacggtgc accttgttcc caaatcacac ggtgcttccg aatggcaggc tgccagagaa
     7081 aactcttgtg ccgaataccc cagagattta gcaaacgttt caagaaaaga accacatccg
     7141 gaagagcatg cttcattaat ctccatccgg tcaatcacgc cattattcac aaaaataacc
     7201 ttcatatcct gtccgccgat atcgaggata aaagacacat ccttgttcag ataatgcgct
     7261 gccatataat gggcgatcgt ttcgataatc cccgaatgaa gctgaaaggc agacctgata
     7321 aggtcttccc catatccggt agaacagctt ccttttatat tgagtacggc attctgcttc
     7381 aaacattcat cgttcaactg attcagcccc tcttccacag cttttatcgg attgccgcca
     7441 ttaatattat aataagaata cagaagcctt gaatcttcat ccagtacaac aatctttgtc
     7501 gtagtagaac ctgaatcgat gccgataaag acatcctgtg ttccggcttt caagccggaa
     7561 gatatcatct tatgacggga tattctttct ttccatgctt catattcttc attacttgca
     7621 aaaacaggtt ccaatcctgt tgaggcaagg ttaccgttac cgtttaaagt agtgtcaatc
     7681 ttatcgatca aatgggacag tttacagtaa tcctctttat caagatgaaa tagagcagca
     7741 cctagtgcag ggagcaaagt gccgttggcc ggcagtatga tctctttttc atcgagggac
     7801 aaataatcaa tgaaggcttt ccgcagtgcc ggaatgaagg ttaacggacc accgcaaaac
     7861 aatacgggag ttgtaatatc gcaaccgtgc gccagcgtca ctaccgtttg aactgctacc
     7921 gcacgaaaga tggaagccgc aatattctca cgacttacat ttttagctat cagattctga
     7981 atatccgttt tacagaaaac gccacaacgg gaggcaatag gatatacctg tgtcgcattc
     8041 atggcaagtt gattcaattc atcaatattc actcccagta taatcgccat ctggtcaata
     8101 aaagcgcccg tccctcctgc gcaattgccg ttcatacgca aatcggtcgc ttcggcatcc
     8161 ttaaagaaga cgactttcgc atcttctcct ccgatgtcta tcatagaagt cacatgagaa
     8221 taatcctttt gtatcgcttt cgctgccgca acaacctcct gtacaaacgg caacgaacat
     8281 ttctctgaaa ttcccattcc gatagagcct gttatcctca cggaaatatc tttatctccg
     8341 atttcagata acagctcttt caagaatgat agaattgtct cttttgcttt cgcattgtgt
     8401 ctctcgtact ttgaaaataa tagattatca ttttcatcga cggcaactaa cttcgccgtc
     8461 gttgaaccta catcaattcc tattttaatc atgttctaca ctatgttccc cttagtttga
     8521 cactattgtc aaacacaaaa gtaagaataa gttggacaca tcatttcaat aagctctttt
     8581 tttcggttct tttaacacaa acaaacgatg tctatttctt ccggctatct atttctttaa
     8641 gcaattcatc tacagccatt ttgagttgcg tgtcctctcc tttcactacc gtctccgggc
     8701 tgttggcaac tttgatatca ggttccagct gagtattttc cagataactg ccatccggta
     8761 ggcgatagcc gatgatagga atcccaaata ctaatgaagg gtcctgcaaa gtttcccaag
     8821 atacacttgt catagttccc gggacaggca tacctaccag ttttccaatg ttctgatgct
     8881 tgtacaccca cggagtgcca tgcgcattcg aataattggc ttcacactgc aacataatag
     8941 aaggcttgtt ccagcgacga cttggcatat cacaggcttc acgtccgcgt accacctgag
     9001 tgaaatattt ctgaccactg aaaagaattt caatatcttc atgcagacga ccgcctccgt
     9061 taaaacgggt atcgatcaca attccgtcac agttattgta ttttcccaga atatccgagt
     9121 aaacagtacg gaaactgcca tctcccatag attgaatatg aacgtatccc aaacgaccgc
     9181 cggaccattt ctccacatcc tcagcacgtt gtttcaccca acgtttatat aataagccat
     9241 taagctgtcc gcttgtgaca ggttttacca cttcttccca acgttcctta ttctgtgggt
     9301 tgtacagcga aaccagtgtt tttttccctg ccttattatt caaaagatca gtgatgtcct
     9361 tatccggagt tatttcttcc ccgttgattt tttctataat gcaccctgcc tttactttgg
     9421 tacgggaatg atcgaacggg cctttctcta cgatttcagc aatctgcata ccttttccca
     9481 gataattcca gtcaaacaat aagcccagat tagaggttac atccccattg cccctcggag
     9541 aatagcgccc tccggtatgc gaaacattca gttcacctaa ccattcgctc agtaattctg
     9601 caaaatcata gttattatca atatgcggca gaaatttacg ataggcagct gtcatggcat
     9661 cccagtccac tccgtgcata ttaagattgt agaaacgttt ttgatgttgt ttatatacat
     9721 gatcgaacat tgcctcacgt tcggctgcca aatccatttt catttcagcc tgataactga
     9781 tagatttcag agcatctgac tttgcgtcca ttttctgcat atttctgctt cccagcaaga
     9841 agatatctcc ttttttatcc agcatcagtg atgaccagcc ggaattaagt ttatggagac
     9901 gcttcgtatc tttttcacga agatttattt tccaaaggtc atacccctct tcgaaagctg
     9961 agaagtaata cagattttct ccatcttttg aaagaatggc actacctaaa tcagaagagt
    10021 taggagtcag gcgtacaata cggtcctcaa taccgctgag ttccacaaca atatctttct
    10081 tgtctgcctt gtcttcttcg gtatcctcct tatctccttc tttgtctgcc ttttcctttt
    10141 tagacttact tccgtccttt ttcttatcac cgtctttctc ctttgctttc ttctgctcct
    10201 tttcaaattc tttgagcagt tcgaaatcct ctttactcaa acgataacgg tcgtaagcat
    10261 cctgattcaa gaataccagc atcacatcct gttgtgatcc ccaggaagca tgcgcacgca
    10321 taccataacg ttcggtctga aacagaatgg cattcccatc cagcacccaa cgtggagagc
    10381 cgctaatata accgctgtta gtcagattag tgatagtacc tccctgcgcg ctgacaatgc
    10441 cgatatccga atagggatca tgacgattgc cgataaactc aagcgtaaac cacttgccat
    10501 cgggcgacca ttcgtagtcg aatccgcctc ctgtattgta ccatgtagaa ccgtctgtca
    10561 cctgacgtac ttttttggtt ttcagattga gtaccatcaa ccggttacgg tcttcgataa
    10621 aagccagttc cttaccatcc ggagagtatt gcgggtaagc acgttctatg gttttggagg
    10681 gaagcaatac ttcttcttca atgagagtgg cgttagggaa attcgcctct tctttacgag
    10741 ctatcttagc agtataaagt tgccagttgc cggtccgctc gctggcgtaa accagtgtac
    10801 ggttgtcggg agcaaaagat acaccggctt cctttgccgg agtatttgtt atttgcttgg
    10861 tcgtagcata atcggttgaa gtcacaaaaa catcacctcg cacaataaaa gccacctgct
    10921 taccatccgg agacacagaa gcggaagtcg caccctgaga aaatctgaga gtggca
//
