LOCUS       c00137_gnlPro..         9495 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EDGALAIC_137.
ACCESSION   c00137_gnlPro..
VERSION     c00137_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 02:48:35
            Original ID  :: gnl|Prokka|EDGALAIC_137
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9495
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9495
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2706:7563]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2707..7563
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..9495
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9495
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             32..601
                     /locus_tag="ctg137_1"
                     /transl_table=11
                     /translation="MKISFSRQTKERAFKQLYEDYYAPFCLYAKRFVDDKEVREDIVSD
                     VFTSLWDKLDTDSFDLQSETALGYIKMCVKNSCLNFLKHQEYEWSYAENIQKKAPLYET
                     ETDSVYTLDELYRMLYETLNKLPENYRTVFMKSFFEGKTHAEIAEEMNLSVKSINRYKQ
                     KTMELLRNELKDYLPLFLLFLSPEQL"
     CDS             complement(575..1681)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.9; E-value:
                     7.6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg137_2"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-17, bitscore:
                     52.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMIFDRQKQRLLLEGKEYTPGDIHSLVAEGEGNHPSAIWDLYLFL
                     NEWFNDDPVITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLCMNLRYI
                     GAMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEKEKLKQT
                     EILIIGGGAVDKALEEKIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYYPFSSVE
                     LFLSSENTLMINAPLVCDDTLQTNDIARIYPDGSFTILGRKDNVINSGGIKVQAEEIER
                     LLQSSIPVPFVITSVPDRRLGQAVTLLIEGQMEISALGTKLESVLASYYRPKYIYTVNH
                     IPQTGNGKINRKECRVLAESLQLLGRQE"
     CDS             complement(1678..2703)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg137_3"
                     /sec_met_domain="MR_MLE_C (E-value: 3.9e-29, bitscore:
                     91.0, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNWVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSSKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAETEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             complement(2707..3531)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_4"
                     /sec_met_domain="ECH_1 (E-value: 1.6e-82, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             complement(3535..5202)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.4e-09, bitscore:
                     25.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPIVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKTGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKTIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIVIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             complement(5222..6334)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg137_6"
                     /sec_met_domain="Chorismate_bind (E-value: 2.4e-58,
                     bitscore: 186.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     FDLKELNGQRGFVIAPFRIDKSCPIVLIQSDRTGQPLPMEIVAEEEQDLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             complement(6331..7563)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_7"
                     /sec_met_domain="HBT (E-value: 1.6e-17, bitscore: 53.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKSLELGNYGGYILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNN
                     FALFTYHDDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEEAL
                     VSLEGHWKRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELDVKREEVIAIGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKVCADYVTASNEEDGVALAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             complement(7648..8010)
                     /locus_tag="ctg137_8"
                     /transl_table=11
                     /translation="MVQVRIKRVYEDFSETDGYRVLVDKLWPRGIKKEWLKYDYWAKDI
                     TPSAALRRWFHEDIPGHWNDFVVMYQKELEASQAVADFLTLIKPHPVITLLYTSKEPVY
                     NHARILRDYLEMHLKE"
     CDS             complement(8081..9493)
                     /locus_tag="ctg137_9"
                     /transl_table=11
                     /translation="QAGWQGCQPGSRQACRPFRLQRKGAESKLLFCIGENKWQLSFKEE
                     AYDYFDKAIKLLQGTSSKLEMAMLSYFYGMKMDYLLNDSRSKEALEVGLKREKLLKDIA
                     KLPEKTKGFLDLQYTYLYAKMSYICYLEGKYDQAEKYYQQYLSTENSQTPDGKTYAIPY
                     LLVSKQYQKVVDQCQDFKKLMQEQDTVNLQYISILQKEVKAYKGLKDFEKVAALRESII
                     SIIDGINSKDKQNAALELNAIHKADEQEEYIAEQTLQLRIRNISLAFLGCVTCLILFVL
                     WRIWRHTIIVKYKNKMLAKFINEKLAGKVENKQLFIDGDAEDPIAVPLDLEPETGFSEK
                     DDLSPDEVVESREEEDENKKIFKELNRIVVQDQLYLSPELSREDLAQIVHLNNARFARM
                     IKENTGTNFNGYINELRINYAIQLLKQHPNYTIRAIADEAGFNSTPILYSMFKKKTGMT
                     PYEFKKTQESLG"
ORIGIN
        1 gtaaaatgaa aaactacaga atctcaaaat aatgaaaata tctttttcca gacagactaa
       61 agaaagagct ttcaaacaac tttacgagga ttattatgcc cctttctgcc tgtatgcaaa
      121 aagatttgta gatgataaag aagtccgcga ggacattgtt tcggatgtat tcacctccct
      181 atgggacaag ttggataccg actctttcga tttgcaatca gagacagcat tgggatatat
      241 aaaaatgtgt gtaaaaaaca gctgtttgaa ctttctgaaa catcaggagt atgaatggag
      301 ttatgccgaa aatatccaaa agaaagctcc tctatatgaa acagaaacag atagtgtata
      361 tacacttgat gagttatacc gaatgctata cgaaacatta aataagcttc cggaaaacta
      421 tcgcaccgta tttatgaaaa gtttctttga aggcaaaaca catgcggaaa ttgccgaaga
      481 aatgaatctc agcgtaaaat ccattaatcg gtataaacaa aaaacaatgg aactcctgcg
      541 gaacgagttg aaagattacc tcccgctgtt tttattattc ctgtctcccg agcaactgta
      601 agctctctgc taaaacacgg cactctttac gattaatctt cccatttccc gtttgaggaa
      661 tatgatttac cgtataaata tatttaggac gataataaga tgctaagact gattccaatt
      721 tagtccctag cgcacttatc tccatctgcc cttctatcaa taaagtaaca gcctgcccca
      781 aacgccgatc cggaacggaa gtgatcacaa acggtacagg gatagacgac tgaagtaacc
      841 tttcgatctc ttctgcctgc actttaattc ctccgctatt gattacatta tcctttcttc
      901 ccagaatcgt aaaactaccg tccggataaa tgcgggcaat atcatttgtc tgcagagtat
      961 catcgcaaac aagcggagca ttaatcatca aagtattttc tgaagacaaa aacaactcta
     1021 cggatgaaaa aggataataa cgatcggatg ctgctgcgcc attcagacgg cgaagagcga
     1081 tgtgagaaag ggtttccgtc atcccgtaag ttgaataaac agcattggac agatttctga
     1141 ttttttcctc taaagccttg tcaactgctc cgcctcctat aattaaaatc tccgtttgct
     1201 ttaatttctc tttctcttcg ggtatctgaa atgtattata cacctgcaaa ggcaccatag
     1261 ccgcaaacct taaaggagtg tccacatctg ccaatggatg accggaagcc cgacgtacta
     1321 taagattcaa cccggcaatc aaagaacgga cgactaccat catcgccccg atatagcgaa
     1381 ggttcataca caataatgcc gtttcaccct gctttaaatc cagaaactca caagtcaggc
     1441 gtgcactctg tatcatctga tctttgcgaa caagcaattc tttaggtgcc cccgtagaac
     1501 cggaagtatg tacagtgatc acaggatcat cattaaacca ttcgtttaga aaaagataca
     1561 agtcccatat agcagaaggg tggtttccct caccttctgc tacaaggcta tgtatatcgc
     1621 ccggagtata ttcctttccc tccagcaaca aacgctgttt ttgtcggtcg aatatcatca
     1681 tttacaaaac cacaaacaat cttttctgat ttcaagaggc atctctacat tatctgtaaa
     1741 gagtaacccg gtgcctaacc cttgcggcaa tggattctga aaagtagcac accattgagc
     1801 gatagcattc agaccgatat tagactccag agcagaagtt atccaccaac cgatattcag
     1861 tttctccgtt tctgcaatcc actcctcgcc accggctaat ccgccatgaa gagaaggttt
     1921 gataataata tattgcggac ggatagccga aagtaatctt tgcttttctt cccaggtatt
     1981 atagcctatc agttcctcat ccaaagctat cggcaaagga gattcggaag taagacgtgc
     2041 catttcttcc cattgtccgg cacgaatggg ctgttctatc gaatgtaagt ccagttcgga
     2101 caagcgtttc aatttctcca tcgcatctgt tggtgagaat gctccgttgg catctacacg
     2161 caattctatt tctttagaag aatagtgaga gcggatatgt tggagtaaag ccagttcttc
     2221 ttcaaagttg atggcaccga tcttcaactt tatacagcgg aatcccgcct ccatcttctt
     2281 ctctatctga gcaagcattc tattgaagtc acccatccag ataagcccgt ttatcggaat
     2341 acctgcttcc ccacgtgaga agggtgtatc ccacaaagcc cagcttcctt caaaaaagtg
     2401 acgaatggct gtctccaagc caaaaaggat ggaagggtac ttgcatagag cttccatgtc
     2461 cagcttacct ccctgattct ctacctgccg gcagatttta gccagcactt cctcgtaatc
     2521 gggaagatca tcacagctaa gatttggcag aggagcgcac tccccgatcc ctacccaatt
     2581 gggaaattcg ggagcagtaa aatgaagata ccagactttt cgcgttgtgt atgtgcctcg
     2641 tgaagttccg gccggctgct tgaaatgaag cacccgcgga ataatgtcta ttttgcaatc
     2701 cattgtttaa gggaacttcg gatatttctt aaagttaggt ttacgtttct ccagaaatgc
     2761 attctttcct tcctgagcct catccgtcag atagtaaagc aaggtcgcat cccctgccag
     2821 ctcctgaata cctgcctggc cgtccagttc ggcattcaat ccggctttaa tcatccgcaa
     2881 ggccaacgga ctgagcagca tcatttcttc cgcccattgc acatactcat cctccagttg
     2941 ctccaatgga actactttat tcaccaatcc catatccaac gcttcctgcg cattgtattt
     3001 ccggcaaagg aaccatatct cacgtgcctt cttctgaccg acgacacgag ccagataaga
     3061 ggctccgaaa cctgcatcaa agctacctac gcgaggaccg gtctgtccga agatcgcatt
     3121 ctccgaagca atcgataaat cgcaaactac atgaagcacg tgtccgccac caatggcaaa
     3181 tccatttacg gcagcaatta ccggtttcgg aatgctgcgg atttgtttct gtacatccag
     3241 aacactcaga cggggaacac cgtccttgcc gatatagccg ccacgccctt tcacattctg
     3301 gtcaccgccc gaacagaaag ccttgtcacc agctcccgta atcacgatca catcaatatc
     3361 cgcttcttcc cggcaaatgc gcaatgcgtc actcatttca gccgttgtag tcggagtaaa
     3421 tgcatttcga tagcgttcac ggttaatggt gatgcgggca atcccattat agtaatcaaa
     3481 gaggatatct tcgtattctc tgatggttgt ccattctctt tgtgttgaca taatctattt
     3541 ttgttttagt tgatgataat aatctttcag tatacgtgca tctttatttt tattgctgaa
     3601 tacttccatc agaaccggtt gttccatggc ttccggttgt gtgaaggttt tcatcgcttc
     3661 ggcaagctgt tcttcattct ctacccgttg ataaaggaat ccgcgttctt ccgcccatcc
     3721 tttggcagat gtcttgtgaa cggctgtaat atacttgtgc gatgtacccg acatatccag
     3781 tccgggtaat gtatggaaaa tctcccctcc tccgttattc agcaaaagaa tgcgtagatt
     3841 gggacggaca ttgatgttcc acaaagcatt catatcataa aagaaactaa ggtcacctat
     3901 aactataaaa tttagtttat ccgaaccggc ggcatatccc actgccgtgg acaacgagcc
     3961 ttcgatgccg cttgtacccc gattacagca tacctcaatc gtagaaggaa cctggtataa
     4021 ctgagcatag cggataacag aactatttgc cagatgcaat gcacatgatt ccggcaatgc
     4081 ttttatcaaa gcaccgatag ccgacatttc cgaatatccg aactccggtt cgggaatggt
     4141 cttgcaataa ttctcccata cacggggata ctccggcacg cggttatcca gcaatggagc
     4201 tattttctcc agaaactcaa acgggtccat ttcgatgacg gtagtcagag aaccgtaaag
     4261 gtcaaccact tctccatcag cagacacatg ccaatgttct ttaggcggat gctgccgaag
     4321 atattttttc aaccgcttgg aaaccacatg tccgccataa gtaatcaata actcgggagt
     4381 catctggccg gttttctctt cgggcatcgc ataaagcgcc gcatcaaaat tcttcactgg
     4441 aataccgggt actgtctgat taccgatatg ctcggtcagc cacacgaaat gtttatataa
     4501 caatttggta tgccgtttct caaacaagta aatcaagttc atctgtccga caataatcat
     4561 ccgcttctga tatctgttca agcgttcgat caggtcattg taatcccggt cgtatacatt
     4621 cagcccctga tagcgcgtaa tgacacgtac ttcgggaagc gactccaccg taaactggaa
     4681 caaaggttcg gatataggaa tattaatatg taccggacct tttccatgat ggttggtttc
     4741 cagcaaggct tcattcacca agcggttaca gtaccattca tcctcttctg tctgaatctc
     4801 cggaaggttt accgacttct tcaccaatgt ctgaaaaaca ccgggctgcg gcaatgtctg
     4861 tcccgccatc tgtccaatcc aggcagcagg ccgatcggca gagataacaa ctaaaggtat
     4921 attctgataa tacgcttctg ccacagcagg atgaagattg agcaacgctg taccggaagt
     4981 acagcaaacg gcagcaggat gcccgccatt cagcgcaaga ccaatcgcaa aataaccggc
     5041 actccgttca tccgtcatag cataacaagt aaaacccgga tgagtagaca gcgtatgcac
     5101 aataggtgca ttacggctac cgggacataa cactactttc gtaattccat gcgcctcaag
     5161 cagcgcgacc aactggagta tatttttctt gtccgaatac atattgatag tgattagctt
     5221 gttagtgatt catcattatt ggagcagaca caagaatacg cctcatggtc tgcaatttct
     5281 tttccgtttc ctgccattca tcattcaact ctgaagaggc taacaatccg ccaccggcat
     5341 acagtgtcaa ttgctcgtct tcaatgtgca tgcaacgcag attcacatac aaatctgtgc
     5401 gtccctccgg atcgagccaa ccgataaaac cggaataata cttacgatcg tacccttcat
     5461 tttccaaaat gaaccggtag gcttcttctt taggcagtcc gcacacggca ggagtcggat
     5521 gcaggacttt cagaaggtct cccagatttt tattatcttt caaagagaaa tggaaatcag
     5581 ttttcagatg tgacaaggca ccggcataag ccggataagg tccgctctct gtggagcgaa
     5641 tgcccagcga aagaagctgc cgacggatat aggacgccac ataatcctgc tcctgacggt
     5701 ttttgtcatc ccatacttgc ggaagtttac cattctgcaa aggttgagtt cctgccaggg
     5761 caactgtgtt ccattcattt ttttcgcccg acaatataat ttcgggggta cttcccagcc
     5821 acacgcccgt ctgaggagta taacacagat agatatagga atgaatataa cgttgacaag
     5881 ctgcacgaaa aacagctgaa ggggaaaact ccggattctt tccaatagtg agactacggg
     5941 aaagcaccag tttatcaaag gtagcatcac gcaaggcttc aataaatgta tgaaaacagg
     6001 tcgcatactt cccagtacaa agggtatgaa aagattcctc cggataactt tgcaagtcct
     6061 gctcttcctc tgccacgatt tccataggca acggttgtcc agtcctgtcg gactgtatca
     6121 acacaatcgg acatgactta tctatacgga acggagcaat cacaaatcct ctttgtccat
     6181 tcagttcttt caaatcgaaa atcaagcgga cagctccgac atcttctgtc aacagacgag
     6241 gatacttctc cccgggaaca cgataaacag caaagggctg tttccgctga ataagtgcat
     6301 caatagttgt caagttactt ttttcgtcaa tcatcttttt ttcatcacac tgttgaccac
     6361 ccgtatagag gacaccagtt tattggttga agtaaaaacg tccacattcc atacatggga
     6421 ggaacgtcct ttgtgtacaa tcgtcgctac tgcacgtact gtatcacctt cgtgcgcaga
     6481 agatatatga tttccgctga cctgcattcc taccacaatt tcatccggct gacagagaat
     6541 catcgagccg agtccggcaa ctgtttctcc caatgcaagc gtagctccac cgtgcaaaat
     6601 accgaacggc tgacgggtac ggtgatctac cggcatcgtc gcctctacac ggtcttcgtc
     6661 ggcatatgta tattggatac ccagattacc catcaatgcg tgacgcgcct gtgcattcaa
     6721 ctggtccaaa ggaatctctg cagcgcgaac ttccgctatt atcgcctttt cgacagccag
     6781 agccactccg tcttcctcat tggaagctgt cacataatcc gcacagacct ttaccgaatc
     6841 ctgcgaatgc cccatcgcca ctcccagtcc tgccagctga atcatcgtta catcgcacac
     6901 accgtctcct atagcgatga cttcttcacg cttcacatcc agttcttcca ataaagctcc
     6961 caatgtgttg gctttatcaa tcgcacacgg cactacttcc agaaaataag gttcggaacg
     7021 gaaaacatcc aaagctccgt tcaaccgtct cttccagtgt ccttccagac taaccaacgc
     7081 ttcctcgtca tcgctgacaa gcatacactt acacggagca aagtcaattg ctacagaaaa
     7141 ttcctcttcc ttgatcactt tcaaattatt caagcgagct tcattctgga tatgttcatt
     7201 ctccggagtg tcagtaatga tcgtatcatc atggtaagtg aacagtgcga aattattttt
     7261 tcttgccttc ttttccagat aaggcaacat ttccggatta atcctccgct caaacagtat
     7321 ttctccgttt tgagcattaa ttatctggca accattataa gaaaggatat aacctccata
     7381 atttccgagt tctagggatt tggctaaagg catcagaccg taagtcggtc ggccggatgc
     7441 caacacgata cgtactccca tctgctgaac tttcagcaaa gcagccaatg tacgtttact
     7501 aatttctttt gcatcattga gaagcgttcc gtctacatca agaactaata atttatactt
     7561 catggacaca cgattttgat ttagattaca aaggtaggaa attgagtgaa cgactgaaag
     7621 cggaaagaga taaaaattac tttaatttca ctctttcaga tgcatttcca aataatcacg
     7681 aaggattcgg gcatgattat aaaccggttc tttggatgta taaagcaaag tgatcaccgg
     7741 atgaggtttg ataagagtca gaaaatcggc aacagcttga gaagcttcca gttccttctg
     7801 atacattacg acaaaatcat tccagtgacc cggaatatct tcatgaaacc atctgcgcag
     7861 tgctgcggaa ggcgttatat cttttgccca gtaatcatat ttcaaccatt cttttttgat
     7921 tccacgtggc cagagtttat ctaccagcac ccgatatccg tcggtctctg aaaagtcttc
     7981 gtacactcgc tttatcctaa cttgcaccat ttccgtttat atttagttat cataagaata
     8041 aaccgataaa acggaaaatt gtttatcgaa aaagccaaaa tcaacctaag gattcctgcg
     8101 tttttttaaa ttcgtaagga gtcataccag tctttttctt gaacatactg tacagaatag
     8161 gcgtactatt aaatccggct tcatcagcta tcgcacgaat ggtataattg ggatgttgct
     8221 tcaataactg aatcgcatag ttaatacgaa gttcattaat atacccgttg aaattagttc
     8281 cggtgttttc cttgatcatc cgggcgaaac gcgcattatt caaatgtaca atctgagcca
     8341 gatcctctct cgacaattcc ggagacagat ataactgatc ctgaacaaca atacgattca
     8401 gttctttgaa aattttctta ttctcatcct cttcctccct actctccact acttcatccg
     8461 gagataaatc gtctttttcg gaaaagccag tttccggttc caagtccaat ggaacagcta
     8521 tcggatcttc cgcatctcca tctatgaata attgtttgtt ctctactttt ccagccagtt
     8581 tctcattgat aaactttgcc agcattttgt ttttatattt aacaataatc gtatgacgcc
     8641 aaatccgcca tagcacaaat aaaatgagac aagtgacaca tcccaaaaaa gcaagtgata
     8701 tgtttctgat tcttaactgt aaagtctgtt cggcaatata ttcttcctgc tcgtcagctt
     8761 tatgaatagc atttaattcc aaagccgcat tctgtttatc cttgctgtta ataccatcaa
     8821 taatagaaat aatagactca cgtaatgctg ctactttttc aaaatccttc aagcctttat
     8881 aagctttcac ctctttctga aggatactaa tatactgcaa gttgacagta tcctgctctt
     8941 gcatcaattt cttaaaatcc tgacattgat caacgacttt ctgatattgt ttagacacta
     9001 gcagataagg tatcgcatag gtttttccat ccggtgtctg tgaattctct gttgacaaat
     9061 attgttgata atatttttcc gcctgatcat actttccttc cagatagcag atatacgaca
     9121 tttttgcata caagtaagta tattgcagat caagaaagcc ttttgttttt tccggtaatt
     9181 tagctatatc tttaagtagc ttttcgcgct tcaacccaac ctccaatgct tctttactac
     9241 gggaatcatt gagcagataa tccattttca tcccataaaa gtatgaaagc atagccattt
     9301 ccaatttgga acttgtacct tgaagcaatt tgatagcttt gtcaaaatag tcatatgcct
     9361 cctctttgaa agacaattgc catttatttt caccaatgca aaacaacagc ttactttcag
     9421 cccctttcct ttgcaggcga aacggtcggc acgcctgcct gcttccgggc tgacatcctt
     9481 gccaacctgc ctgcc
//
