LOCUS       gnlProkkaILJGGLAL_549   5684 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ILJGGLAL_549.
ACCESSION   gnlProkkaILJGGLAL_549
VERSION     gnlProkkaILJGGLAL_549
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 07:26:19
            Original ID  :: gnl|Prokka|ILJGGLAL_549
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5684
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5684
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2432:5677]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2433..5677
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..5684
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5684
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             2..496
                     /locus_tag="ctg549_1"
                     /transl_table=11
                     /translation="MNIVMYDAEHRKIKEMLEKNGQDKEYKIIPVNEDNLTHVFRITEA
                     LDKKEYVCFQGDRYLNKEKLLTGCLLGEEAPFPAGPFLLASRMKVPVVFYFAMREPGRT
                     YRFHFFVAEPVTRSKEKKAETALLEQYTATLEHILKRYPEQWFNYYSFWKPATKQATDS
                     I"
     CDS             507..1577
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 136.6; E-value:
                     1.9e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg549_2"
                     /transl_table=11
                     /translation="MQQNRYDKEPMTAVEAQRLAQEIAFGPIVFQVSRLMLKFGIFQLL
                     ADRREGLTQEEISKACGLSSYAVQVLLEASLTIGTVLLCEGHYQLAKAGWFLLNDKMVR
                     VNMDFNHDVNYLGMFHLEEALTEGRPEGLKVFGEWSTIYEGLSSLPTQVQKSWFGFDHY
                     YSDRSFDEALSIVFARHPKTLLDVGGNTGRWATRCVSYSPTVEVTIMDLPQQLEMMRQQ
                     TKELPEAARIHGHGANLLDPAVPFPTGFDAIWMSQFLDCFSEEEVTSILTRAARSMNKE
                     GRLYIMETFWNRQKFDTAAYCLTQISLYFTAMANGNSKMYHSDDMKRCIEAAGLEIEEI
                     HDHLGMGHSIVQCRLK"
     CDS             1574..2008
                     /locus_tag="ctg549_3"
                     /transl_table=11
                     /translation="MNKEATIHGEGILGLIPQRPPIVMVDCFFGIEENRSYSGLTVTAD
                     NIFCEAGKLQEAGLIEHIAQSAAARIGFLYTQQGKEAPLGFIGSVDKLKIYSLPDVGQK
                     LLTEITVVQEVFDITLISAQVKADEELTTECRMKIFIKKE"
     CDS             2005..2448
                     /locus_tag="ctg549_4"
                     /transl_table=11
                     /translation="MKRKTNQHSAALTNRTTLRVRFSEIDSMQIVWHGEYVRYFEDGRE
                     AFGKQYGLDYMSIYREGYMVPIVDLTCQFKQSLSFGEEAIIETRYIACDAAKIHFEYVI
                     YRATDQSVVATGSTIQVFLNLNKELELVNPPFYTEWKKKWNIL"
     CDS             2433..4166
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (127-377). E-value:
                     1.2e-28. Score: 92.0. Matches aSDomain:
                     nrpspksdomains_ctg549_5_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 169.3; E-value:
                     2.4e-51)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg549_5"
                     /sec_met_domain="APE_KS2 (E-value: 1.8e-106, bitscore:
                     345.3, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHPLNIYITAHTLISSLGFGTEENLKAIRTYRSGVHLQEAGPDS
                     ESNRISDTPIQAGLIDSAELEKRTRQAQIEAYPRLEQLFILTIQEILSQSGANLRKQDC
                     ALLLSTTKGNIDLLGDSPVFLGKMAERIGSFFRTANRVEVISNACISGVSALIVAKRWI
                     ETGRYKQVIVAGGDILSHFITSGFLSFRSVSAQRCRPYDKQRDGLNLGEACGAVLLSTA
                     GSAKDILLSGGAVSNDANHISGPSRTGDGLALAISQAMKEAGVTPEDISFINAHGTATI
                     YNDEMESKAIHLAGLSSVPVNSLKPYVGHTLGASGIIESILCIEQLKEGIMYGTLGYET
                     PGVPMPVIVNAAHQSIAMKSCIKTASGFGGCNAAIVLSLPAYQKQGQSCVIQPITTCQT
                     VSIKRGTVKLAGKTIFSSQETEFAPFIREAYKSLGENNMKFYKMDDLCKLGYVAAGYLL
                     KDTAYQPEKIAILLANTSSSLDTDCKHQAIISKDGDAAASPAVFVYTLPNVVLGEICIR
                     HKIQGENTFFVSQSYDEALLEDYARIVMAKGKLQTCIIGWCELFDGHYHAEFKQLIYQH
                     P"
     aSDomain        2814..3563
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg549_5_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.20E-28"
                     /label="ctg549_5_PKS_KS.1"
                     /locus_tag="ctg549_5"
                     /protein_end="377"
                     /protein_start="127"
                     /score="92.0"
                     /tool="antismash"
                     /translation="MAERIGSFFRTANRVEVISNACISGVSALIVAKRWIETGRYKQVI
                     VAGGDILSHFITSGFLSFRSVSAQRCRPYDKQRDGLNLGEACGAVLLSTAGSAKDILLS
                     GGAVSNDANHISGPSRTGDGLALAISQAMKEAGVTPEDISFINAHGTATIYNDEMESKA
                     IHLAGLSSVPVNSLKPYVGHTLGASGIIESILCIEQLKEGIMYGTLGYETPGVPMPVIV
                     NAAHQSIAMKSCIKTASGFGGCNAAIVL"
     CDS             4163..4447
                     /NRPS_PKS="Domain: PP-binding (23-87). E-value: 9.6e-12.
                     Score: 37.2. Matches aSDomain:
                     nrpspksdomains_ctg549_6_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg549_6"
                     /sec_met_domain="PP-binding (E-value: 1.2e-12, bitscore:
                     37.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEFTSEKERELRDEVKGKLIEELNLEEITPEDIDDEAPLFGDEG
                     LGLDSIDALEIILILEREYGIKIENPGKGKEIFYSVRTLADYITANRKK"
     aSDomain        4232..4423
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg549_6_PP-binding.1"
                     /evalue="9.60E-12"
                     /label="ctg549_6_PP-binding.1"
                     /locus_tag="ctg549_6"
                     /protein_end="87"
                     /protein_start="23"
                     /score="37.2"
                     /tool="antismash"
                     /translation="LNLEEITPEDIDDEAPLFGDEGLGLDSIDALEIILILEREYGIKI
                     ENPGKGKEIFYSVRTLADY"
     CDS             4451..5677
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (75-397). E-value:
                     2e-40. Score: 130.8. Matches aSDomain:
                     nrpspksdomains_ctg549_7_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 266.3; E-value:
                     8.5e-81)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg549_7"
                     /sec_met_domain="APE_KS2 (E-value: 6.7e-125, bitscore:
                     406.0, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIYVTGLGVISGIGIGVSENIEALKQKRHGIGKVTLFPTALDVP
                     VSEVKCDNEKLKQLLSLSPLQTVSRTALLGMMAAKEALEDAGLPMQGTRNTPQQQPLRI
                     GFISATSVGGMDLSEHFYEAFKQDPSRGQLREVISHDCGASTELIASYLGIRDFVTTIS
                     TACSSAANAVMLGARMIRHGQLDAAIVGGTDALCRFTLNGFHSLMILDKDHCRPFDRSR
                     AGLNLGEGAGYLVLQSEKSLQRTPYCELSGFANTNEAFHQTGSSPEGDGAFSSMSEAIA
                     SSGVSAEEIDYINVHGTGTPGNDASEGTALRRIFGKAVPPFSSVKAFIGHTLGASEGIE
                     AVYSVLSIYKGMVYPNLNFTEPMPETGLVPETSFREGLPIRHVLSNSFGFGGNDSSLLF
                     SVVNEPLSI"
     aSDomain        4676..5641
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg549_7_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.00E-40"
                     /label="ctg549_7_PKS_KS.1"
                     /locus_tag="ctg549_7"
                     /protein_end="397"
                     /protein_start="75"
                     /score="130.8"
                     /tool="antismash"
                     /translation="MMAAKEALEDAGLPMQGTRNTPQQQPLRIGFISATSVGGMDLSEH
                     FYEAFKQDPSRGQLREVISHDCGASTELIASYLGIRDFVTTISTACSSAANAVMLGARM
                     IRHGQLDAAIVGGTDALCRFTLNGFHSLMILDKDHCRPFDRSRAGLNLGEGAGYLVLQS
                     EKSLQRTPYCELSGFANTNEAFHQTGSSPEGDGAFSSMSEAIASSGVSAEEIDYINVHG
                     TGTPGNDASEGTALRRIFGKAVPPFSSVKAFIGHTLGASEGIEAVYSVLSIYKGMVYPN
                     LNFTEPMPETGLVPETSFREGLPIRHVLSNSFGFGGNDSSL"
ORIGIN
        1 gatcaacatt gtgatgtacg acgccgagca tcgcaaaatc aaagaaatgc tggagaaaaa
       61 cggacaggac aaggagtata agattattcc ggtcaacgaa gataatctga cgcacgtgtt
      121 ccgcattacc gaagcactgg acaaaaaaga atatgtctgc tttcaaggcg accgctacct
      181 gaacaaagag aagctgctga caggctgttt actgggagag gaagctcctt ttcctgccgg
      241 tccttttctg ctggcttcgc gcatgaaagt tccggtagtg ttctactttg ccatgaggga
      301 accgggaagg acgtatcgtt tccacttctt tgtggcggaa ccggtgacac gaagcaaaga
      361 gaaaaaggcc gaaaccgccc tgctggaaca atatacagcg actctggaac atatcttgaa
      421 acgttatccg gagcaatggt ttaattatta ttcattctgg aagcctgcaa caaagcaagc
      481 tacagattca atataaaaac atagagatgc aacagaatag atatgacaaa gaaccgatga
      541 cagcagtaga ggcccaacgg ctggcacagg aaatagcttt cggacctatt gtattccaag
      601 tgtcacgact gatgcttaaa ttcggtattt tccagttact cgccgaccga cgcgaaggac
      661 tgacacagga agaaatcagc aaggcttgcg gactgtcctc ctatgccgta caggtactgc
      721 tggaagcatc gttaacaatc ggtaccgtcc tcctttgtga aggacactac cagcttgcca
      781 aagccggctg gttcctgctc aacgacaaaa tggtacgggt gaatatggat ttcaaccatg
      841 atgtcaacta tctgggaatg ttccatctcg aagaagcact gactgaaggg cgtccggaag
      901 gtctgaaagt attcggtgaa tggagtacta tttatgaagg actgtccagt ctgccgactc
      961 aggtacagaa gagttggttt ggcttcgacc actattactc ggatcgctct ttcgacgaag
     1021 cactgtcaat cgttttcgcc cgccatccca aaaccttact ggacgtagga ggtaataccg
     1081 gacgatgggc aacccgatgc gtaagttata gcccgacggt agaagtgacc atcatggacc
     1141 ttccacaaca actggaaatg atgcgccaac agaccaaaga attgcccgaa gcggcacgta
     1201 ttcacggaca cggtgccaat ctgctcgatc cggctgttcc ttttcccact ggatttgatg
     1261 ctatctggat gagccagttc ctcgactgct tctcggaaga ggaggtaacc agcattctga
     1321 cccgtgcggc acgttctatg aacaaagagg gccgtcttta tatcatggaa accttctgga
     1381 accgtcagaa gttcgataca gccgcctatt gtctgactca aatcagtctt tattttacgg
     1441 ctatggccaa tggaaacagc aagatgtatc attcggatga catgaaacga tgcatcgaag
     1501 cggcaggtct ggagatagaa gaaatacatg accacctggg gatggggcac agcatcgtac
     1561 aatgcagatt gaaatgaaca aggaagcaac catacacgga gagggaatac tcggactgat
     1621 tccgcagcgt ccaccgatag tcatggtgga ttgtttcttc ggcatcgaag aaaaccgttc
     1681 gtattcggga ctgaccgtca ccgccgacaa tatattctgc gaagcaggaa agctacagga
     1741 agcaggactc atcgaacata ttgcccaatc ggccgccgca cgtatcggat ttctttatac
     1801 acagcaaggc aaggaggccc cattgggatt tatcggttcg gtggataaac taaagattta
     1861 cagcctgccg gatgtcggac agaaactatt gacggagatc accgttgtgc aggaagtctt
     1921 tgacattacc ttgatttcgg cacaagtaaa agcggatgaa gaactgacaa ccgaatgccg
     1981 gatgaaaata tttataaaaa aagaatgaaa cggaaaacaa atcagcacag cgcagctctg
     2041 accaaccgga ctacactcag agtacggttc agcgagatag actccatgca aattgtatgg
     2101 catggagagt atgtacgtta ttttgaagac ggaagagagg ctttcggcaa gcaatacggt
     2161 ttggactata tgagcattta cagggaaggt tatatggttc ccatcgttga tttgacctgt
     2221 cagttcaaac agtcgctgtc ctttggcgag gaggcgatta tcgaaacacg ctatatcgcc
     2281 tgcgatgcag ccaaaatcca tttcgaatat gtgatctacc gggctacaga ccaaagcgtt
     2341 gtagctaccg gaagcactat acaggtgttt ctgaatctga ataaagaact tgaacttgtt
     2401 aatcctcctt tttacacgga gtggaaaaag aaatggaaca tcctttgaat atatacatca
     2461 cagcccatac gctgatcagc tcgttaggct tcggtacaga ggaaaacctg aaagcgatcc
     2521 gtacttaccg gagtggagtc catctgcagg aagcaggacc ggattctgag agcaaccgga
     2581 tatccgacac cccgatacag gcaggactga ttgactccgc cgaactggaa aagcggacac
     2641 gacaggcaca gattgaggct tatcctcgct tggagcaact gttcatactc accatacagg
     2701 agatactttc ccagtcggga gccaatctcc gcaaacagga ttgtgccctg ttactttcta
     2761 caaccaaagg aaatatagac ttgttgggcg acagtcctgt cttccttgga aaaatggctg
     2821 aacgaatcgg aagtttcttc cggacagcca atcgggtgga agttatttcc aatgcctgca
     2881 tatcaggtgt atctgcctta atcgttgcca aaagatggat agaaacagga cgttacaaac
     2941 aagtgattgt ggcaggggga gatattcttt ctcactttat caccagcggc ttcctgtctt
     3001 tcaggtctgt cagcgcgcag cggtgtcgcc cgtatgataa acagcgggat ggcctgaatc
     3061 tgggcgaagc ctgcggagcc gtattactga gtacggcagg cagtgcaaag gatatactgc
     3121 tttcgggggg ggctgtcagc aacgatgcca atcacatctc cggtccgtcc cgaaccggtg
     3181 acggcctggc tctcgccatc agtcaggcta tgaaagaagc cggagtaact cccgaagata
     3241 tcagttttat caatgcacat ggcactgcta cgatctataa cgatgaaatg gaatccaagg
     3301 caatccatct ggcaggtctg tcttcggtac cggtcaacag tctgaaaccg tacgttggcc
     3361 atacattagg agcttccggg attatcgaaa gcattctttg tatcgagcag ctgaaggaag
     3421 gcatcatgta tggaacatta ggatacgaga ctcccggagt gcctatgcct gtcatagtca
     3481 atgccgccca ccaatcaatt gcgatgaaat cctgtatcaa gacggcttcc ggtttcggag
     3541 gatgcaatgc cgcaattgtt ctctctctcc cagcttatca gaaacaagga cagtcatgcg
     3601 tcatacaacc cataactacc tgtcagaccg tctccatcaa gcggggaacc gttaaactag
     3661 cagggaaaac catcttcagt tcacaggaaa cagaatttgc accgtttatc cgtgaagcgt
     3721 acaaaagcct gggcgaaaac aacatgaagt tctacaaaat ggacgatctt tgcaaactgg
     3781 gttatgtagc tgccgggtac ctgctgaaag acacagccta tcagccggaa aaaatagcga
     3841 ttctacttgc caacacctct tcgtcgctgg atacggactg caaacaccag gctatcatca
     3901 gcaaagacgg agatgccgct gccagccctg ccgtattcgt ctatacgctc cccaatgtcg
     3961 tactgggcga aatatgtatc cgccacaaga ttcagggaga gaatacgttc tttgtcagcc
     4021 agagttacga tgaagcactg ctggaagatt atgcacgtat cgtaatggcc aaagggaagc
     4081 tgcaaacctg tatcatcggc tggtgcgaac tatttgacgg acattatcac gcagaattta
     4141 aacaacttat ataccaacac ccatgaacga atttacaagc gaaaaggaaa gagaattaag
     4201 agacgaagtg aaaggtaaac tgatcgaaga gttaaacctc gaagaaatca ctccggaaga
     4261 tatcgacgac gaagcgcccc tgttcggaga cgaaggactc ggcctcgatt cgatcgacgc
     4321 gctcgaaatc atcctgattc tggaacgtga atacggcatc aaaatcgaaa atccgggtaa
     4381 aggaaaagaa atcttctatt cggtacgtac cttggccgat tacatcactg ccaaccgtaa
     4441 aaagtaatcc atgaagattt acgtcaccgg actgggagtc atttcaggta tcggcatcgg
     4501 agtttctgag aatatagagg ctctgaagca aaagaggcat ggcatcggga aagtaaccct
     4561 tttcccgaca gcactcgatg tgcccgtatc tgaagtgaaa tgcgacaatg agaaactgaa
     4621 acagttgtta tcgctgtctc cgctacaaac agtttcccgt acggcactgc tcggaatgat
     4681 ggcggccaaa gaggcactgg aagatgccgg actccctatg cagggcacac ggaatacccc
     4741 acagcagcaa ccgctgcgca tcgggtttat atccgctacg tctgtcggtg gcatggatct
     4801 cagcgaacat ttctacgagg ctttcaagca agatccctcc cggggacaac tgcgggaagt
     4861 gatttctcac gattgcggtg ccagcacgga actcattgct tcatatctgg gcatcagaga
     4921 ttttgtaacg accatcagca ccgcctgttc gtcagcagca aacgctgtca tgctgggagc
     4981 ccgaatgatc agacacggtc agctggacgc tgccatagtg ggaggcacgg acgccctctg
     5041 ccggttcacg ctgaatggat tccattcgct gatgattctg gacaaggatc actgccgccc
     5101 tttcgaccgt tcccgtgccg gattgaatct cggtgaaggg gccggatacc tggtacttca
     5161 atcggaaaag tcactccaga gaactcccta ctgtgagcta agcggatttg ccaatacaaa
     5221 cgaggctttt caccagacag gcagctctcc ggaaggagac ggcgcattct cttccatgag
     5281 cgaggcgatt gcctccagtg gtgtctctgc ggaagaaatt gattatatta acgtacatgg
     5341 cactggtacc cccggcaatg atgcttcgga aggtaccgca ctacggagaa tctttggcaa
     5401 ggctgtcccg cctttcagtt cggtaaaagc atttatcgga catacgttag gagcttccga
     5461 aggcattgag gctgtctatt ccgtactctc tatatataaa ggtatggttt acccgaatct
     5521 gaattttacg gaacccatgc cggaaacggg attagtgccg gaaacatcct tccgtgaagg
     5581 attacccatc cggcatgtac tgtccaactc cttcggtttc ggagggaacg actcatcgct
     5641 ccttttttcc gttgtcaacg aacctttaag tatctgacct atgc
//
