LOCUS       gnlProkkaONFFCOJN_358  15943 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ONFFCOJN_358.
ACCESSION   gnlProkkaONFFCOJN_358
VERSION     gnlProkkaONFFCOJN_358
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 03:11:34
            Original ID  :: gnl|Prokka|ONFFCOJN_358
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15943
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15943
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5592:5943]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5593..5943
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15943
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15943
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             408..3236
                     /locus_tag="ctg358_1"
                     /transl_table=11
                     /translation="MKNLIALTLLLGGSTLLCAQKPAKTPATYKPVKSEMYRKGWIDFN
                     KNGVKDVYEDPSAPLEARIENLLQQMTLDEKTCQMVTLYGYKRVLKDDLPTPEWKELLW
                     KDGIGAIDEHLNGFQQWGLPPSDNAYVWPASRHAWALNEVQRFFVEDTRLGIPVDFTNE
                     GIRGVESYRATNFPTQLGLGHTWNRELIRQVGLITGREARMLGYTNVYAPILDVGRDQR
                     WGRYEEVYGESPYLVAELGIEMVRGLQHNHQVAATGKHFAAYSNNKGAREGMARVDPQM
                     SPREVENIHIYPFKRVIREAGMLGVMSSYNDYDGIPVQGSYYWLTTRLRGEMGFRGYVV
                     SDSDAVEYLYTKHGTAKDMKEAVRQSVEAGLNVRCTFRSPDSFVLPLRELVKEGGLSEE
                     VINDRVRDILRVKFLIGLFDAPYQTDLADADREVEKEENEAIALQASRESIVLLKNAGE
                     LLPLDINSTKKIAVCGPNANEEGYALTHYGPLAVEVTTVLEGIQEKTKGKAEVLYTKGC
                     DLVDAHWPESEIIDYPLTDDEQAEIDKAVENARQADVAIVVLGGGQRTCGENKSRTSLD
                     LPGRQLQLLQAIQATGKPVVLILINGRPLSINWADKFVPAILEAWYPGSKGGTALADIL
                     FGDYNPGGKLTVTFPKTVGQIPFNFPCKPSSQIDGGKNPGPTGNMSRINGALYPFGYGL
                     SYTTFEYSDLDITPRVITPNESATVRLKVTNTGKRAGDEVVQLYIRDVLSSITTYEKNL
                     AGFQRIHLEPGEAQELSFTIDRKHLELLDADMKWVVEPGDFVLMAGASSEDIRLNGTLT
                     VEDYQTRAKAIEAQKPAKRVSASTNPEDAENVLDEKINTAWQGNKGDYITFALKNGAKV
                     DKVAIAFTRDNNLPATFEIQLSGGGGQFLTVYSGTVSEYGKLISYPFKGTTASDLRIVL
                     NDDRVSIAEVKF"
     CDS             3359..4465
                     /locus_tag="ctg358_2"
                     /transl_table=11
                     /translation="MLGLGLTACGSSPKGTNGDQDELAMLIGTYTNGSSKGIYTFRFNQ
                     ETGTAVPLSSAALPNPSYLVPSEDGEFVYAVSEMNDSTAALSSLAFDRETGELRLLNTV
                     PTFGADPCYVATNGREVLTANYSGGTMSVFPLQKDGTLAPADTLFQGSATGPDAIRQAT
                     PHIHCTVFSPDGKYIFATDFSADRILRFVMHPDNPIPHASLEAVGIEADSGPRHLTFSP
                     NGKFAYLITELSGKVIAFSYDDGCLEQIQTITADTVAARGSADIHLSPDGKYLYASNRL
                     KEDGIAIFAVNPENGTLAKVGYQPTGIHPRNFNITPNGKYLLAACRDSNVIQVYKRNEV
                     TGLLEDTHQDIVVDMPVCVQFVSSVNNL"
     CDS             4527..5585
                     /locus_tag="ctg358_3"
                     /transl_table=11
                     /translation="MYIMKKNILMLSALFLSITAMAQTDVTTGVMRGKDYGVTYMLPKT
                     EIEIVLQATKHTYTPGEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGVPDKDNVYF
                     VKMKDKTVAPLMELTEDGIVRSINIPFSGKPAAKTPEAKATESSIDPRSFLTEEILMSN
                     SSAKMAELVAKEIYSIRESKNALLRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGK
                     IKKEPKTFTIRLTPKEMKDEVAFRFSRKLGVVANNDLAGEPYYISVTDLKSPDVSATEE
                     GKKKVDGVAYNLPGKAQVTLMYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFD
                     TATGGLIKVDRE"
     CDS             complement(5593..5943)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg358_4"
                     /sec_met_domain="PqqD_RRE (E-value: 3.7e-10, bitscore:
                     31.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.6e-17, bitscore: 53.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRRF
                     LLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLARHFGEEENYIPRVTAYVMQL
                     RKDGFIQLTIRN"
     CDS             complement(5966..7357)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 101.4; E-value: 7.2e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg358_5"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMAAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFVFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             complement(7511..7900)
                     /locus_tag="ctg358_6"
                     /transl_table=11
                     /translation="MYLLLVILMLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEA
                     PQSEAPAATTPAETPAPAAEAPAAE"
     CDS             complement(7905..8678)
                     /locus_tag="ctg358_7"
                     /transl_table=11
                     /translation="MTPTHLQQWIQHPETLNRDTLYELRTLVARYPYFQSLRLLYLKNL
                     YLLHDINFGAELRKAVLYVADRRVLFYFIEGDRYTLKSRKVSSLFSGDLEKEPSVDRTL
                     SLIDAFLATVPEEHSQHTELDYAVDYTAYLMQEEPGVDAEDESEVPKLRGHELIDDFIQ
                     KSESSDASDTRREFLVEKEEETEEEEEPSVSPVTEELDDSCFTETLAKIYIKQHRYDKA
                     LEIIKKLSLNYPKKNAYFADQIRFLEKLIINAKSK"
     CDS             complement(8683..9174)
                     /locus_tag="ctg358_8"
                     /transl_table=11
                     /translation="MLVSLLFLVNSCSMKLGLAPISSIDYTKVKTISIADFQNRAEYVY
                     APLATEFNQKMKDMFIQQTRLQLVNSGGDLEIDGEITGYNQYNESVDASGYSSKVKVTL
                     TVNVRYTNNTNHEEDFEQQFSAFQTYDSSKLLTEVQDQLITLMVKDIAEQIFNATVANW
                     "
     CDS             complement(9194..10444)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 379.9; E-value:
                     3.1e-115)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg358_9"
                     /transl_table=11
                     /translation="MTKAEIQQVKLRFGIIGNNEALMRAIDIAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EANGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVEKTDVRIVAATNVNLTQAI
                     ADGRFREDLYYRLNTVPIQVPPLRERGEDVVLLFRKFASDFAEKYRMPAIQLTEDGKQV
                     LLGYSWPGNVRQLKNITEQISIIETNREINASILKGYLPEQNNMQRLPALFGVKEDKSF
                     GSEREILYQVLFDMRQDVTDLKKLVHEIMAERGTVANPAVATSAYYTPATPAVVPPVTS
                     SVPTIIHPSVKPVTPVDDDFQDTEEYVEESLSLDEVEKEMIRKALEKHHGKRKSAAQDL
                     NISERTLYRKIKEYGLD"
     CDS             complement(10446..11543)
                     /locus_tag="ctg358_10"
                     /transl_table=11
                     /translation="MEDNKIRVGITQGDINGVGYEVILKTFADPVMLELCTPIIYGSPK
                     VAAYHRKSLDLPTNFSIVNSASEAVPNRLSVVNCTDDEVKVEFSKPDVEAGKAALGALE
                     KAIEEYKEGMIDVIVTAPINKHTIQSEEFAFPGHTEYIEQKLGDGEKALMILMKDDFRV
                     ALVTGHIPVKEIAGSITKELIQEKLKIFNRSLKQDFAISAPRIAVLSLNPHAGDGGLLG
                     TEEQEIIIPAINEMAAKGMLCYGPYPADGFMGSDNFTHFDGILAMYHDQGLAPFKALAM
                     DEGVNYTAGLPVIRTSPAHGTAYDIAGKGIASEDSFRQAIYVAIDVFRNRQREKEAHAN
                     PLRKQYYEKRDDSDKLKLDSVEEDL"
     CDS             complement(11549..12604)
                     /locus_tag="ctg358_11"
                     /transl_table=11
                     /translation="MRKHLFYLSMVLVLTLFSACGGGKKGVFTPTSSGRAYEVLVVVEP
                     GLWERPAGRALFDVLDSDVPGLPQSERSFRIMYTAPSNYDATLKLIRNIIIVDVNKDLY
                     TQPKFKYARNVYAAPQSILTIQAPDEASFEKFVEENRQVIIDFFTHAEMNRQISVLKDK
                     HSDYIATKVKSQFDCDVWVPGELTSTKEGENFFWAGTNAATGDQNFVIYSYPYTDKDTF
                     TKEYFVHKRDSVMKVNIPGAREGMYMSTDSLMTDVRPISVQGDYALEARGLWRIKGDFM
                     GGPFVSHVRLDKANQRIIVSEIFIYSPDKMKRNLVRQMEASLYTLKLPGSKQEGAEIPV
                     GVTSKDTTNNK"
     CDS             complement(12675..13727)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg358_12"
                     /sec_met_domain="PF04055 (E-value: 7.4e-17, bitscore: 53.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNDMQKRPLLGLTLSELQNVVKNLGMPGFSAKQIASWLYDKKVT
                     SIDEMSNLSLKHRELLKEIYEVGAEAPVDAMRSVDGTVKYLYRAGEGHFVEAVYIPDED
                     RATLCVSSQVGCKMNCKFCMTGKQGFTANLTSNQIINQISSLPERDKLTNVVMMGMGEP
                     LDNLDEVLKALEIMTASYGYAWSPKRVTLSSVGLKKGLQRFIEESDCHLAISLHSPIPL
                     QRRELMPAEKAFSITEIVELLRNYDFSKQRRLSFEYIVFKGVNDSLPYAKELLKLLRGL
                     DCRINLIRFHAIPGVNLEGADMETMTAFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTA
                     KQEENKEELI"
ORIGIN
        1 ttttccatac ccaaccttgg gatgtctaaa ccaaggttgg gtttagacat cccaaggttg
       61 aaaagaaagt tcttccgtac aagcaacaat tccgccaaca gattcctatt atataaatac
      121 accctcgttt aacagatgta gccgtaatac ttgtatacac cgcgattgca tctacttttc
      181 aggttattat agtgttctct ctttcttttt aaaagtgaat gatatgtttc gtctaataat
      241 gatttgaatt ccccggtagc gtcttggagg atatttttag taagaggaag acccttcgga
      301 caataaaagc cgatacttcg gactatttta tccctttatt tcacacatta gccgtatttt
      361 tgtcaacaaa agaaacaata ataaccaaga gatttttaga acatatcatg aagaacctta
      421 ttgccctaac cctgctgctt ggaggaagca cactgctctg cgcacaaaag cctgccaaaa
      481 caccggcaac ctacaagccg gtgaaaagtg aaatgtaccg caaaggttgg atagacttca
      541 acaaaaacgg agtgaaagac gtgtacgaag acccctccgc cccgctcgaa gcacgcatcg
      601 aaaacctgct gcaacagatg acgctggacg aaaagacctg ccaaatggtc accctctacg
      661 gctacaaacg cgtactgaaa gacgacctcc ccacccccga atggaaagag ctgctctgga
      721 aagacggtat cggcgccatc gacgaacacc tgaacggctt ccagcaatgg gggctgcctc
      781 cctcggacaa tgcctacgtc tggcccgcct cgcgccacgc ctgggcactg aacgaggtgc
      841 aacggttctt tgtggaagat acccgtctcg gcatccccgt agactttacc aacgaaggca
      901 tacgcggcgt ggaaagctac cgcgccacca acttccccac ccaactggga ctgggacata
      961 cctggaaccg tgaactgatt cgccaagtag gactcatcac cggacgcgaa gcccgcatgc
     1021 tgggctacac caacgtctac gcccccatcc tcgacgtagg acgcgaccag cgctggggac
     1081 gctacgaaga agtttacggc gaatctccct acctcgtagc cgaactgggc atcgaaatgg
     1141 tgcgcggctt gcagcacaac caccaagtgg ccgccaccgg caagcacttt gccgcttaca
     1201 gtaacaacaa aggcgcccgc gaaggcatgg cacgcgtgga cccgcaaatg tcgccgcgcg
     1261 aagtggaaaa catacacatc taccccttca aacgcgtcat ccgggaagct ggcatgctgg
     1321 gcgtaatgag ttcgtacaac gattacgacg gcatccccgt gcagggcagc tactactggc
     1381 tcaccacccg cctgcgtggc gaaatgggat tccgtggcta cgtcgtatcc gacagtgacg
     1441 ccgtagaata cctctacacc aagcacggca ccgccaaaga catgaaagaa gccgtccgcc
     1501 aaagcgtgga agccggactg aacgtacgct gcaccttccg ctcgcccgac tccttcgtcc
     1561 ttcccctccg cgaactggtg aaggaaggcg gactgagcga agaagtcatc aacgaccgcg
     1621 tgcgcgacat ccttcgggta aagttcctca tcggtctgtt cgatgccccc tatcagacag
     1681 accttgccga tgccgaccgt gaagtggaaa aagaagagaa cgaagccatt gccttgcagg
     1741 catcccgcga gtccatcgtt ctgctgaaga atgccggtga actattgccc ttagacatca
     1801 actccaccaa gaagattgcc gtctgtggtc ccaatgccaa tgaagaaggc tacgcgctga
     1861 cccattacgg cccacttgcc gtagaagtga ccactgtgct ggaaggcatt caagaaaaga
     1921 caaaaggcaa ggcagaggtg ctctacacca aaggctgcga cctggtggac gcccactggc
     1981 ccgaaagtga aatcatagac tatccgctga ccgacgacga acaagccgag atagacaaag
     2041 ccgtagaaaa tgcccgtcaa gctgatgttg ccatcgtagt attgggcggc ggacaacgca
     2101 cctgcggcga aaacaaatcg cgcaccagcc tcgacctgcc cggtcggcag ttgcaactgc
     2161 ttcaagccat acaagccacg ggcaagcccg tcgtactgat actcatcaac ggacgcccgc
     2221 tctccatcaa ctgggcagac aagttcgtcc ccgctatcct cgaagcctgg tatcccggct
     2281 ccaaaggcgg aacagccctg gccgacatcc tcttcggcga ctacaacccc ggtggaaagc
     2341 tgacggtgac cttccccaag accgtagggc aaatcccctt caacttcccc tgcaaacctt
     2401 cttcacagat agacggcggt aagaatccgg gacctacggg caacatgtca cgcatcaacg
     2461 gagcactcta ccccttcggt tacggcttga gctacaccac cttcgagtac tccgacctcg
     2521 acatcacccc ccgagtcatc accccgaacg agtctgccac cgtccgcctg aaggtgacca
     2581 acaccggcaa acgtgccgga gatgaagtag tgcagctcta tatccgcgac gtactgagca
     2641 gcatcaccac ctacgaaaag aatcttgcag gcttccagcg catccacctc gaaccgggcg
     2701 aagcccagga gctgtccttc accatcgacc gcaagcacct ggagcttctg gacgctgaca
     2761 tgaaatgggt ggtggaaccc ggcgacttcg tgctcatggc cggcgcctct tccgaagaca
     2821 tccgcctgaa cggaacgctg accgtagaag actaccagac ccgtgccaaa gccattgaag
     2881 cccaaaaacc agcaaagcgt gtgagtgcca gcaccaaccc agaggatgcc gaaaacgtgc
     2941 tcgacgaaaa aatcaatacc gcatggcaag gaaataaggg agattatatt acctttgcct
     3001 taaagaacgg agccaaggta gataaagttg ccattgcctt tacacgtgac aacaacctgc
     3061 cggcaacctt cgaaatccag ctctcgggcg gtggcggaca gttcctcacc gtatattcgg
     3121 gcaccgtcag cgaatacggc aaactgattt cctatccgtt caaaggcact accgccagcg
     3181 acctccgcat cgtgctgaac gatgaccgcg tcagtattgc cgaagttaaa ttttaatgtg
     3241 ctaatgtgcc aatatgctaa tgtaccaatg accatgcagc atatacagcg cagccaatta
     3301 gcacattagc atattggcac attaacacat taaattaatg aaaacacttc ttttctgtat
     3361 gctcggatta ggtttgacag catgtggctc ttctccaaag ggcactaacg gtgaccagga
     3421 cgaactcgcc atgctaatag gtacttacac gaatggctca agcaagggta tctatacctt
     3481 ccgctttaat caggagacgg gaacagccgt tccgctcagt tcagcggcat tgcccaatcc
     3541 ctcctacctc gtcccctcgg aagatggcga atttgtctat gccgtcagtg aaatgaacga
     3601 cagcacagca gccctcagct cccttgcctt cgaccgggaa acgggagaac tgcgcctgct
     3661 gaacaccgtt cccaccttcg gcgccgaccc ctgctacgtg gccaccaatg gccgggaagt
     3721 gttgactgcc aactacagcg gtggaaccat gtccgtcttt cctttacaga aagacggcac
     3781 tttggctcct gcagacacgc tctttcaagg ctctgccacc ggtcccgacg ccatacggca
     3841 agccactccc cacatccatt gcacggtctt ttcaccggac ggaaagtata tcttcgccac
     3901 cgacttcagt gccgaccgca tcctgcgctt tgtgatgcac cccgacaacc ctattcctca
     3961 tgcttctctg gaagccgttg gcattgaggc agattccggc ccgcgccatc tgacattcag
     4021 ccctaacggg aagtttgcct atctcatcac cgaactgtcc ggtaaggtca ttgccttcag
     4081 ttacgacgac ggctgcctgg aacagataca gactatcaca gccgacaccg tagccgcccg
     4141 tggaagtgca gacatccacc tcagtccgga tgggaaatac ctctacgcca gcaaccgtct
     4201 gaaagaagac ggcatcgcca tctttgccgt gaatcccgaa aatgggacct tggcaaaggt
     4261 aggttatcag cccaccggca tccatccccg caacttcaac atcacgccca acggtaaata
     4321 cttgcttgcc gcctgccgcg acagcaatgt cattcaggta tacaaacgaa acgaagttac
     4381 cggactcttg gaagatactc atcaggacat tgtagtcgac atgccggttt gcgtacagtt
     4441 cgtcagctct gttaataatt tataaagcaa tatttagcaa agataacttc attaactttg
     4501 tcccttagct aaatcagtct aaacgaatgt acattatgaa gaagaatata ttgatgctct
     4561 cagctctgtt cttgtctatc actgccatgg cgcaaacaga cgtaaccacc ggtgtgatgc
     4621 gtggcaaaga ctacggagtg acttatatgt tacccaaaac agaaatagaa atcgtattgc
     4681 aagccaccaa gcatacctac actcccggag aattttgcag atatgccgac cgctatctgc
     4741 gtctcaacaa cgtgtctgcc gaacccgagg agttctggac actggataag atagaaaccc
     4801 gcatagccgg tgtaccggat aaggacaacg tctatttcgt gaagatgaaa gacaagaccg
     4861 tagcacccct tatggagctt accgaagacg gaattgtccg ctccatcaac attccgttca
     4921 gcggtaagcc tgctgccaag acgcccgaag ccaaagccac cgaaagcagc attgacccac
     4981 gcagttttct gacggaagaa atactgatgt ccaactccag tgccaagatg gccgagctgg
     5041 tggctaagga aatatacagc atccgcgaaa gcaagaatgc cctcctgcgc ggcgaagcag
     5101 acaatatgcc caaggacggc gcccaactca agctgatgct tgacaatctg aaccagcagg
     5161 aaacggctat gacggaaatg ttctcgggca aaataaagaa agaacccaag acattcacca
     5221 tccggctgac gcctaaagag atgaaagatg aggtggcttt ccgtttttcc cgaaagctgg
     5281 gagtggtggc caataatgac cttgccggtg aaccgtatta tatcagcgtc accgacctca
     5341 aaagtcccga tgtatctgcc accgaggaag gcaaaaagaa agtggacggt gtagcctata
     5401 accttccggg caaggcacaa gtgacattga tgtataacaa taagaaattg tttgacgacc
     5461 aacttcccat tacccaattc ggcaccgtag aatacctcgc accggtactg ttcaacaaga
     5521 attctaccat caaagtgctg tttgatacgg caacgggagg attgataaaa gtggataggg
     5581 aataaaggaa ttctaattcc ggattgtcaa ctggataaat ccatccttac gcaactgcat
     5641 tacgtaggcg gtgacccggg gaatataatt ctcttcctcc ccaaagtgcc tggcaagtag
     5701 agagatgatt tcgcgcacgg tacgatgtcc atctatcaga ttccagacag ctgtaccgtg
     5761 ttcttccagc ctcacatgga tgtcaggaga catccccttc ggcaataaaa aacgacgcat
     5821 ccattcgtat ttaaaccgtg ggtaggcgag tacggcgcac tcaccttccc attcggttgt
     5881 tatatgtcca cagcggaccg gaacagcgtc caacagactt acttttcctt cgggtatttc
     5941 catcatacgg tatccgcttt tcctattatt tctgaatatt aggctcttcc agcttataac
     6001 catacttctt gtctgccttc ttcagcagta gagccactat aagggacaag caggcaatac
     6061 cggtaaaaat gcacataggc accgtatagt catacatatt cgttccatct ggtttcttgc
     6121 cggatataca ataggcatca agcacccacc ctatcaatgt aggaataccc caaagaccga
     6181 tattctggat aaagaaaatc aatgcgtatg ccgtacccaa ctggcttacc gggaatatct
     6241 tggccacagc cggccacatg gcagaaggta ccagcgagaa agcgataccc aaaattatca
     6301 tcagcacaat agctaccagc caatagttta tatcgggaat agcataaatg aaatgcacac
     6361 atatcagcat ggccgagccc agcagcatga tagatgcgga cttgccccgc ttgtcaatga
     6421 aaccaccaaa gaccggagtc agaatcagcg ctcccaatgc cggaagtccg gcaaatgtac
     6481 cggccacatt ctcattgata ccgtatttga taatcatcaa ctcggaagca aacttctgga
     6541 atgggaatac acaagagtag aacaatacac acagcaatgc tatcagccag aaaccgggat
     6601 tgaccagaat attcttcaca tccttaaaag agaacttctc ttcctcatct tccgtaccgg
     6661 cagcaatggc agcagcttcc atctgtttgt ccagcttctt gtccatcact gcaaagacga
     6721 agaaagcaat cataccgccc aacaacagaa ccaaacccaa caacaccggt gtggaaatac
     6781 cgaaagcgcg ggccaaagga atggctacgg cataaccggc ttgcgaaccg atacgtgcta
     6841 aagcgacttg tacccccata gccgtggcaa gctctttccc cttaaaccac ttggctatga
     6901 ttttggaaac tgtaataccg gcgacctccg ctcctactcc aaaaatggaa taaccggcaa
     6961 aagcaacaaa cacacccgtt ttatagccaa atatttcatt gattccgaat aaagtcgcgt
     7021 cggcaccggc aagtcccgtc attgcatagt attcaagtgc tgtaccacct accatcagga
     7081 tagttgccag ctttccggtg aaacggatac caaagcggtc gaggattaat cctccccaaa
     7141 tcaacatcag gaaaaaaaca ttcagaaaac tataaccacc ggtaaagaat ccgaaatcgg
     7201 tactcgacca agccaagtcc gtttccaaca ttgtcttcaa cggtgctacc acgtcgttta
     7261 cataataagc tgccatcatc gtgaaggcaa caatcaccaa tgccccccaa cgggtagcct
     7321 tggaatcatt caatttaagt ttgagttgtt ctgtcattgt actatttgga tttcaattta
     7381 ttaatcagat tgcataaatt gctgacaaag gtaaataaat acttcatcaa aacgaaaaaa
     7441 ggctgacacc ttttcagtat caacctttct cttatttttc caagcgggag tcatccgcaa
     7501 tatccttatc ttattctgct gcaggggctt ctgctgcagg agcaggagtt tcagccggag
     7561 ttgtagctgc aggggcctcc gattgcggag cttctgtacc tacgggcatg ttataaggat
     7621 tagttttttc ttcttgttgc gcctgttcca gaatcacatc accgcccttg cctgtggaag
     7681 aaggaatagt gtaagcagaa acaatactga agactaccat gacagctgcc agagtccagg
     7741 ttgctttttc caaaaagtcc gtagtcttgc gcacacccat aatttggttg gatgatgaaa
     7801 agcctgatgc cagaccacct cctttagaat tttgaatcaa tacaatgaag cacatcagca
     7861 cagatgcaat cagcattaag ataactaata ataaatacat tttgttattt tgatttagcg
     7921 ttaataatca atttctccaa aaatctgatt tggtctgcaa agtaagcatt tttttttgga
     7981 taattcaaac ttaatttttt aataatttca agcgccttgt catatcggtg ctgttttata
     8041 tagattttgg ctaaagtttc cgtaaaacag ctatcgtcca actcttccgt taccggcgat
     8101 actgagggtt cttcctcttc ttcagtctct tcctccttct ctacaagaaa ctcccttctc
     8161 gtatccgagg catccgaaga ctcactcttt tggataaagt catctatcaa ttcatgcccg
     8221 cgcagtttag gcacttccga ctcatcttct gcatccacac cgggttcttc ctgcattaaa
     8281 taggccgtat aatccaccgc ataatccagc tccgtatgct gtgaatgctc ttcgggaaca
     8341 gtagccagaa atgcgtcaat caaggaaagg gtacggtcca cactcggctc tttctccaaa
     8401 tcgccggaaa acagcgacga gaccttccgg gatttcaaag tatagcggtc accctctata
     8461 aagtaaaaca gcacacgacg gtctgccaca tacaacacag ccttgcgcaa ctccgcgcca
     8521 aagttgatgt cgtgcagcag atagaggttt ttcagataga gcaaacggag cgactggaaa
     8581 taaggatagc gtgccaccaa tgtgcgaagc tcgtacaaag tatccctatt cagcgtctcg
     8641 ggatgctgaa tccattgttg caaatgggta ggcgtcatga gtttaccagt tagctacagt
     8701 tgcattgaaa atctgttcgg caatgtcttt caccatcaag gttatcagct ggtcctgcac
     8761 ttcggtcagc aattttgagg aatcataggt ctggaaagcc gagaactgct gttcaaagtc
     8821 ctcctcatgg ttcgtgttat tggtgtagcg cacgttgaca gtcagcgtca ccttcacctt
     8881 cgaagagtag ccgctggcat ccaccgattc attatattga ttgtagccgg ttatttctcc
     8941 gtctatttcc aggtctcctc cggaattcac cagttgcagg cgagtctgct gaatgaacat
     9001 atccttcatt ttctggttaa attctgttgc cagcggtgca tatacatact ctgcccggtt
     9061 ctggaaatcg gcaatggaaa tcgtttttac ctttgtatag tcgatagagc ttatcggagc
     9121 aagtcccaac ttcatactac atgaattcac cagaaataac aagcttacca acaaggaagc
     9181 aaatgccgct tttttaatcc aatccatatt cttttatctt tctgtataac gtacgctcag
     9241 agatattcaa atcctgagcc gcactcttac gcttgccgtg atgtttttca agcgccttac
     9301 gtatcatttc tttctccact tcatccaggg agagtgactc ctccacatat tcttccgtat
     9361 cctggaaatc atcgtccacc ggagtaaccg gctttaccga aggatgtata atggtgggga
     9421 cactggatgt taccggaggt accaccgccg gagtagccgg cgtatagtag gccgatgtgg
     9481 caaccgccgg attggctacc gttccccttt cagccataat ctcatgcacc agctttttca
     9541 agtccgttac atcctggcgc atatcaaaca gaacctggta gagaatttcc cgttcactcc
     9601 cgaagctctt gtcctccttc actccaaaca aggcaggcag gcgctgcata ttgttctgct
     9661 caggcagata gcccttcagt atggatgcat tgatttcacg attggtctca atgatggata
     9721 tctgctcggt gatattcttc aactggcgca cattacccgg ccatgagtag cccagcaaca
     9781 cttgcttgcc gtcttccgtc agctgaatgg caggcatacg gtacttttct gcaaagtccg
     9841 aagcaaactt tcggaacagc agcaccacgt cttcaccgcg ttcgcgcaat ggagggacct
     9901 gaataggaac tgtgttcaaa cggtaataca agtcttcacg aaaacgtccg tcagcaatgg
     9961 cttgtgtcaa gtttacattg gtagcggcaa caatacgcac atcggtcttt tccaccttag
    10021 aagaacctac tttgatgaat tcaccgctct cgagcacacg caacaagcgt gcctgggtag
    10081 gcaaaggcaa ttcgccgact tcatcaagga agattgttcc gccgttggcc tcaccgaaat
    10141 accccttccg ttcgccgata gccccggtaa atgcgccctt ctcatgaccg aacagttccg
    10201 agtcaatcgt cccttcggga atggctccac agttcacggc aatgtactgt ccatgcttgc
    10261 gccggctgta ctggtgtatt atctgcggaa agctctcctt tcccacacca ctctctccgg
    10321 taatcagtac agacaagtcg gtgggcgcta cctggatagc gatatcaatg gcacgcatca
    10381 gcgcttcatt gttgccgata atgccgaaac gtaattttac ttgttgtatt tccgcttttg
    10441 tcattctaca aatcttcttc tacactatcg agtttcagtt tgtcgctatc gtcacgtttc
    10501 tcgtaatatt gcttgcgcag cggatttgca tgtgcctctt tctcacgctg gcggttacgg
    10561 aacacatcta ttgccacata gatagcctgc cggaatgaat cttcagaggc gattcctttc
    10621 ccggcaatat cgtaggccgt gccatgagca ggcgaagtgc gtatcaccgg caagccggca
    10681 gtatagttca cgccctcgtc catagccaat gccttgaacg gtgccagccc ctggtcgtga
    10741 tacatggcca ggataccatc aaaatgggta aagttatctg agcccataaa cccgtctgcc
    10801 ggataaggac catagcaaag cataccctta gcagccattt cgttgatggc cggaatgata
    10861 atctcctgct cttcagttcc cagcaatccg ccgtctcctg catgcggatt cagcgaaagc
    10921 actgcaatac gcggtgcgct gatagcaaaa tcctgcttca aggagcggtt gaatatcttc
    10981 agtttttctt gtatcagttc tttggtgatg cttccggcta tctctttaac gggaatatgt
    11041 ccggtcacca atgctacccg gaagtcatct ttcatcagaa tcataagggc cttctcgcca
    11101 tctcccaatt tttgctctat atactccgta tgtccgggga aggcaaactc ctccgactgg
    11161 atggtatgct tgttgatggg agctgtgaca atcacgtcta tcattccctc cttatattcc
    11221 tcaatggctt tttccagtgc accaagtgca gctttaccag cttcaacgtc aggtttagag
    11281 aactcaacct ttacttcatc atccgtacag ttcactacac tcaagcgatt gggaaccgct
    11341 tcggaggcgg agttgacgat actgaagttg gtaggcaagt ccaatgattt acgatgataa
    11401 gctgccactt taggcgaacc gtagataatc ggcgtgcaca attccagcat caccgggtct
    11461 gcaaacgtct ttaaaatcac ttcataccct acaccattaa tgtcgccttg tgtaatgccg
    11521 actcttattt tgttgtcttc catttttatt acttattatt agtagtatct tttgaggtta
    11581 cgcctaccgg aatttccgca ccttcctgct tgctgccggg cagtttcaag gtatagagcg
    11641 aagcctccat ctgacgtacc agattacgtt tcattttatc aggtgaataa ataaatattt
    11701 cagatacgat aatacgctga ttggccttgt ccaaacgtac atgcgatacg aacggaccgc
    11761 ccatgaagtc accctttatg cgccacaagc cgcgggcctc cagtgcatag tctccctgca
    11821 cactgatggg gcgtacatcg gtcatcagag aatccgtcga catatacatg ccttcacggg
    11881 caccagggat attaaccttc atcacggaat cgcgtttatg aacaaaatat tctttagtaa
    11941 acgtatcctt atccgtataa ggataagagt agattacaaa gttctggtcg ccggtagctg
    12001 cattcgtacc tgcccagaag aagttctcac cctccttggt agatgtcagt tcgcccggca
    12061 cccatacatc gcaatcgaac tggcttttca ccttcgttgc tatatagtcg ctatgcttgt
    12121 ccttcaatac tgaaatctga cgattcattt ccgcatgggt aaagaaatcg atgattacct
    12181 gcctattctc ctccacaaat ttctcgaacg aagcctcgtc cggtgcctga atagtgagaa
    12241 tagactgagg agcagcatat acattccttg catacttgaa tttaggctgg gtatagaggt
    12301 ccttgttcac atcgacaata atgatattgc gaatcagttt taaagtggca tcataattgg
    12361 aaggggcagt atacatgatt cggaatgaac gttctgactg gggaagcccc ggaacatcag
    12421 aatcaagcac atcgaaaagc gccctaccgg caggacgttc ccacaagccg ggctccacca
    12481 ctaccagaac ttcatacgca cgaccgctgg aggtcggagt aaacacaccc tttttaccac
    12541 caccgcaagc ggaaaaaagc gtcagtacga gaaccatact caaataaaac aagtgctttc
    12601 tcatatctct atcattttag tttttcacaa agctacgaag aatgcgtaat atcctcccta
    12661 cctaagttaa taatttatat taattcttct ttattctcct cctgcttggc agtggacaac
    12721 atgccacaag cagcaaatat atcctctcca cgcgatgacc gtatagtggt aaacagaccg
    12781 tgcgaagtca gataatcacg gaacgcagtc atggtttcca tatcagcccc ttcaagattc
    12841 actccaggta tggcatgaaa acgaatcagg ttaatccggc agtccagccc gcgtagcagc
    12901 ttcagaagtt cctttgcata cggtaacgag tcattcactc ctttgaaaac aatatattca
    12961 aaagatagtc tgcgctgttt gctaaaatca tagtttctta acaattccac aatctccgtg
    13021 atggagaacg ccttctctgc cggcatcagt tcgcggcgtt gcaaaggtat cggcgaatga
    13081 aggctgatag ccagatggca gtccgattcc tcaataaaac gctgcaagcc cttcttcaat
    13141 cccactgaag aaagggtgac acgcttggga ctccacgcat atccataaga ggcggtcatt
    13201 atttccagcg ctttcaatac ctcgtccaga ttatcaagtg gttcgcccat gcccatcatt
    13261 accacattgg tcagcttgtc cctttcgggc aacgaactga tttggttgat aatctggttg
    13321 gatgtcagat tggcggtaaa gccctgcttg ccggtcatac agaatttgca gttcatctta
    13381 cagcccacct gagaggagac acaaagcgta gccctgtctt cgtcgggtat atagacagct
    13441 tccacgaaat gcccctcgcc tgcccggtac aagtatttca ccgtaccgtc tacagagcgc
    13501 atggcatcta ccggcgcttc ggcacctacc tcatagattt ctttcagcaa ttcccgatgc
    13561 ttcaacgaaa gattgctcat ttcgtctata gaagtcacct tcttgtcata cagccaggaa
    13621 gctatctgct tggcagagaa accgggcatt cccagattct tcaccacatt ctgcaattca
    13681 gagagcgtca agcccaatag aggtcgtttc tgcatatcgt ttttcattaa aaacaaaact
    13741 ctttcaagaa tgcaaaggta ggaataaagt tgcacaaaga caacggagag tatagaaaat
    13801 gaaatgtaca gagaatgaaa aagccgcccg ggagtaccga acggcttttc aatatgggtt
    13861 ttctattctt agaagaataa ataacgttgg tcttttacgt tggctttcag atacaagtca
    13921 ctgatgaact ggcttgccat gcgtgcgtgc atgttagcca agttagcctc ttcagtttcc
    13981 ttgttgaatg tttcgttcag cttctctttt gcataaggtt gcagaacgaa tacaccaccg
    14041 ttacccttga taggagcact cagcttgttc acttcggcaa tagaagcgta tgcgcctacc
    14101 agaggttcgc tgctacgcaa tgccgggata taggcaggag cagagaaagt aacgtgcttt
    14161 acagaatcac taacagcatt tgccatattc ttgtactgct cgaacgaagt tgcattggca
    14221 gccttcatat cagccataat cttctctgct ttcttgtcac ggagaatttc agctctcaac
    14281 tggtccttta ccaaagccag tgggcgataa ccttcaggaa caatacttgc aacacctact
    14341 accagcatac ggtcgctctc gccacattcg tacaaaccgg aaacttcacc ggcttttgcc
    14401 tcaaacgccc atttcaaagc atctttggtt cctctgatac caccgatacc atgttcagag
    14461 ctgtacaagt cggctctatc cagcaacttg taaccggcat cttccgcatt ggcaatcatt
    14521 ttctctaaag tattgtttgc agcgatgaac tggctaaact cattgtatgc cttgctgtaa
    14581 gtttccttgc tgaattctac cggacgcttg ataacggcta ccttatattt atccttgaca
    14641 gccttcttgt tggttacttg caaaatgaca tttgcttgtc ccaacgccag attggtcagt
    14701 tcgttctgtc ccaaagttgt gacagcggta atgtatttca agttgtcacc gtcaatctgt
    14761 gcgccttcgt agttagcaga agaaatccag gtaggctcac cggtctgacc gtacttcttc
    14821 gcaatttcag caaagctggc accaccctta atagcattgc agatgctgtc ggctaaagtc
    14881 ttcgtctttt cagcatcttc ggcaactacc tgaatctgac ggaactcgat agagtccggc
    14941 atggcagcag tagccaattt cttgaaagag ttaagagtat tgtccgatac gttataataa
    15001 ggtccgaata caccacccac cgcaacagaa tccaaacggg ctgtcacatc agcaggcaga
    15061 gacttagtag tgtagaacaa gtctgtataa ggagcttcgg aaccggtaga acggatgaag
    15121 gtagtatagt cagaaggatt ggcagtaagt tgttcggtgt attcttccat ttccttctgg
    15181 agagcagctc tgtcttctgc acttgcagta acttgcacat caatgaactt gatattgcga
    15241 gtttccacat attgcttgaa ctgttctttc ttcttgtcgt atgcagcctt caaatcagaa
    15301 tccttgataa cgatggtaga gtcaacgata gaagaatagg gaactgcagc aagcagcagg
    15361 tctgactgct ctactcttgc atcaaaagcg tcctgagctt ctaccgggtt ggagaaaaga
    15421 gattttgtaa tcaaagcctg atacttctcc tgaagacgtg cctggataag agacttttcg
    15481 aggaaagacc agaacttgta catggattca tagtattctg catattgtga aggcatctgc
    15541 gccttattca tttttgaata gtccaccaag aacttcttca acatatcctt atcaaacgca
    15601 ccggtctgag gattacggaa cggagtctgt tgcagcatcg gatgcacacc ggcattaatg
    15661 atagcctgaa tctcagcctt cgatacaacc agaccgagtt tctttgcttc cttttcaatc
    15721 agcttattat tgacgtatgt tctccatact tcatctttga tttggtttgt ctgctcatcg
    15781 ctcaatgcac tgttgccact ggagaacttg atgacttctg tatattcttc taccaatgct
    15841 tgaaaatcct gagcggaaat tgattccccg ttcacttcac ctacgtcttg tgactggtgt
    15901 ggctgaagca ctttccacgc gtcacctgcg atgaaagcaa aca
//
