LOCUS       c00168_gnlPro..         4356 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ONFFCOJN_168.
ACCESSION   c00168_gnlPro..
VERSION     c00168_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 08:12:26
            Original ID  :: gnl|Prokka|ONFFCOJN_168
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4356
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4356
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4078]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..4078
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4356
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4356
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..391)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg168_1"
                     /sec_met_domain="ALS_ss_C (E-value: 7.8e-10, bitscore:
                     27.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNG"
     CDS             complement(424..2175)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg168_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.4e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRQAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(2276..4078)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg168_3"
                     /sec_met_domain="ILVD_EDD (E-value: 4.3e-219, bitscore:
                     716.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLRSSFSTQGRRMAGARALWTANGMKKEQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRKRLFEDAAKLIVANAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMNELAKGG
                     LVDTNVRRVDGMTLAEAIDRYSITSPDVCKEAIKKYSSAAAGKFNLVLGSQNASYKELD
                     TDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDA
                     ACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKVCALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARPMTPVTRNRE
                     VSKALKAYASMVSSADKGAVRLID"
     CDS             complement(4245..4355)
                     /locus_tag="ctg168_4"
                     /transl_table=11
                     /translation="LTIIHIYLIFFFNLFGDYKKALTFAARLKQKRRIKL"
ORIGIN
        1 tgccattctt ctcaacaatg gcaaatacag cattcacctc cacaatacgg gcattgtact
       61 tacggattac tttggacacc tccggttttt cttccagcgt aggggtcgtt attttataaa
      121 gggcaatctc gtgctgatag atttcatcat ccgtgaaata atgggcttgc agcacatcta
      181 ttttcttggt aatctgcttg gtcacctttt caatggtatc cttatccgtc caagcggtaa
      241 tggtatattt atgtaccccc ttgatggagg aggccgatac attcaaactc tcgatgttta
      301 tctgccggcg ggtaaacaca gccgtcacct gattcagcaa accggcaaag ttttccgaat
      361 gaacaatgat tgtatatagt tttttatcca tagatagagt aaattcttta atttcgcatg
      421 acttcagcat tccaacaaca tctgattgac cgaaccgccc ggaggtgtca tcggcattac
      481 atttccttct tcctccacac aagcttcgag caggaatggt ccgtcagtcg ctatcatctc
      541 gtcaatcgct tttgccagct cctcgcgggt cattaccctg cgtgcaggaa tatcatatgc
      601 cgaagcaatc ttcatataat ccggattcat catcggagta aacgaataac gacgattgaa
      661 gaacatcgcc tgccattgac gaacattgcc caggaagtta ttgttcaaca gaatcatctt
      721 caccggagcc ttttgttcca tgatggtacc cagttcctgc aggttcatct gcaagccgcc
      781 gtctcccatg aatacgcata ccgtgcggtc cggacgtcca aaagtggcac cgatagctgc
      841 cggaaggccg aagcccatag tacccaggcc accggaagta acaatgctac gttccttgct
      901 gtatttgaaa taacgggcgg acatcatctg attctggccg acatcagtca ccaatatcgc
      961 ctcgttatgg gtagcctcac tcacagcacg caccacctca cccatgctta gcgcttttcc
     1021 tgccggatgt aattccggac ggattacctt ttcctcttcc acttcctcgt attgccggaa
     1081 actgtcaatc cattcctgat ggttggcggg ttccagcaat tgggtaacgg cagccagtgt
     1141 ctctttgcaa tctcccagga cagcaacatc ggtctttaca ttcttatcta tttcggcagg
     1201 gtcaatatca aagtggataa tcttcgcctg cttggcatat gtttccaatt tacccgtcac
     1261 acggtcatca aagcgcatgc ctacggcgat aaggacatca catttattgg tattgatatt
     1321 gggccccagg ttaccgtgca taccaagcat tcctttgttc aacggatggt tcgtaggtaa
     1381 tgcggaaagt cccaataaag tgcatccggc aggcattccg gctttctcaa tgaaagcacg
     1441 aagctcttgc tgggcttctc ccagctccac gccttgtcct accagcacca aaggccgttc
     1501 cgcaccattt attaattcag cagcctgccg tatggcctcc ggctccattt cgggaacggg
     1561 aagatagcta cggacatagt ccaccttagt aggcgcatat tctgttttct ccacttgggc
     1621 gtttttagca aaatccagca cgaccggtcc cggacgtccg ctctttgcca catagaaagc
     1681 acgtgccact gcccaggcca catcttctgc acgacgaatc tggtaactcc atttcgtgat
     1741 aggctgagta atgcctacca agtccacttc ctgaaatgca tccgtaccca agaagttcgt
     1801 ccctacctgg ccggcaatga caacgatagg cgtactgtca atcatggcat ctgcaatgcc
     1861 cgtgatagta ttggtagcac ccggtccact ggtaaccaga caaacgccaa cctcgcctga
     1921 tacacgtgca aagccttgtg ccgcatgggt tgctccttgt tcatggcgaa ccaagatgtg
     1981 gttcaattcc ttccggtggt cgtataaggc atcgaatacc ggcatgatgc tccctcccgg
     2041 ataaccgaaa atagtcttta ctccctgatg ctccagagag cgcatcaatg cttctgcgcc
     2101 tgttattaga gcctcacccc gaccctctcc ttgggagagg gaggaaaagt tactcttttt
     2161 attattatca gccatacttt atctattcat tatatttaaa agctcaatag tagcttgaaa
     2221 aatttgtttc attctctcct cccctcgctt tcggaaaggg gtcggggtga ggcttttaat
     2281 caatcagcct cacagcacct ttgtcagcgg aactcaccat actggcatat gctttcaatg
     2341 ctttggagac ttcgcggttg cgagttaccg gagtcatggg gcgtgcagca agctcttcat
     2401 ccgtcaactt cacattaata gaacggttcg gtatatcaat ttcgataatg tccccatcct
     2461 taatcttgcc gatattacca ccagcagccg cttcgggaga aacatgtccg atacttagtc
     2521 cggaagtacc accactgaaa cgcccgtcgg taatcaatgc acacacctta cccagatggc
     2581 gggatttgat ataagaagta ggataaagca tctcttgcat acccggtccg cctttcggcc
     2641 cttcgtgagt gatgacgacg acgtctccac tgaccacctt tccacccaga ataccgtcac
     2701 aagccgcatc ttgtgagtcg aagactttcg ccggccccgt aaatttccag atactctcgt
     2761 ctacaccggc agtcttgaca acgcaaccgt cctgtgctat atttcccttc aaaaccgcca
     2821 gaccgccatc cttgctgtat gcatgttcca aatcacggat acaaccggtc gcacggtccg
     2881 tatcgagttc cttataagac gcattttgtg agccgagtac cagattgaac tttccggctg
     2941 ccgcactgga gtatttcttg attgcctctt tacatacatc agggctggta atactatacc
     3001 ggtcgattgc ctctgccaac gtcattccat ccacacggcg gacattcgta tcgaccaatc
     3061 cgcccttggc aagctcattc atgatggcaa tgatgccacc ggcacggtta acgtcttgta
     3121 catgatactt ttgggtattg ggagccacct tgcataagca gggggtcttg cgagagagca
     3181 tgtcaatgtc gtccatctta aaatccgctc cggcttcgtg agccacagcc aacaaatgaa
     3241 gtactgtatt agtggaaccg cccatcgcaa tatccagcgt catggcattc aaaaatgcct
     3301 cgcgagtagc aatactgcgc gggagtacac tctcatcccc ttcttcataa tatctaaagg
     3361 cattcgctac aatcaactta gctgcatcct caaacagtct cttgcgattt tcgtgagtgg
     3421 ctacaatcgt gccgttaccg ggcagtgcca atccaatcgc ttcattcagg caattcatgg
     3481 aattagcggt aaacatgcct gagcagcatc cgcaagtggg gcaggcatgt tgctcaatct
     3541 gtgccacctc tttatcgccc acactttcat cagcagattt aatcatagca tcaatcaaat
     3601 ccaaatgttg tccgttccat tccccggctt ccatcggacc gcctgaaaca aacacagtcg
     3661 gtatattcag cctcatagcc gccatcagca tccccggagt aatcttgtca cagttactga
     3721 tgcaaaccat agcatccgcc ttatgggcat ttaccatata ctccacacta tcggcaatga
     3781 tatctcttga aggcagggaa taaagcatac cgtcgtgtcc catagcgata ccgtcgtcaa
     3841 tggcaatcgt attgaactcc gcagcaaaac accccagttt ttcaatctct tcctttacaa
     3901 actggcctat ttcgtgcaga tgtacatgcc cggggacgaa ttgtgtaaat gaattgacta
     3961 tagcgataat gggcttaccc atctgttcct tcttcatacc attcgccgtc cacaatgcac
     4021 gggctcccgc catgcggcga ccttgtgtgc tgaacgagct gcgtaactga tgcttcattt
     4081 tcaaatctcc ttttaatgaa aaagcctctc ccactatagt gagaaaggct taataaatta
     4141 tcttctaacg tacgaataca tacataacct ttctcacgct cttgatgcca ccaccacgac
     4201 gcgaataata tgcaggactg ccaggttaat agatgtatgt aaattcataa cttaattctt
     4261 cttttttgtt tcaaacgtgc tgcaaaggta agggcttttt tataatctcc aaacaaatta
     4321 aagaaaaaaa taagataaat atgaataatc gtaaga
//
