LOCUS       gnlProkkaIFFMHHBN_117  14399 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IFFMHHBN_117.
ACCESSION   gnlProkkaIFFMHHBN_117
VERSION     gnlProkkaIFFMHHBN_117
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:18:51
            Original ID  :: gnl|Prokka|IFFMHHBN_117
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1835
            Orig. end    :: 16234
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14399
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10267]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10267
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14399
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14399
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             353..613
                     /locus_tag="ctg117_5"
                     /transl_table=11
                     /translation="MSELKGNDNQKQKASQPCTHVHLCNKSVSARNGCYRISSVWDWKV
                     ISHLVFISPKDTVRVVRGNTTEALKTYTRYGYTCQPFFYCQ"
     CDS             576..680
                     /locus_tag="ctg117_6"
                     /transl_table=11
                     /translation="MDIHANRFSTASNSTLYGSVPYMETLPRTKGGGV"
     CDS             834..1850
                     /locus_tag="ctg117_7"
                     /transl_table=11
                     /translation="MEKQTAVRETLLKEFANCSDKLFTLGIIRTDSFTGEIGEFIASKY
                     FKLSLAGKSTKAYDGVCPKGYKYQIKSKVISNNNFTHHISNLKYQDFDYLVVVYFDIYY
                     NPISILKIPSNKINTEEYIIGASSVLSFSQNIARLKLLQKEQVAIRNFAQSYLNLQKEG
                     IIRSRKVVGDIGEYYACKRLNLKLSSNKNEKGLDAIGQGGLTFEIKTRRVYDSERRTSE
                     TRRINNLIGKNADYLIVVTLNHAFECSGMWIMPMKNIINPKSANLKIVNTTIGVKNLVP
                     SQISWLNTGEKFVSFNCMDKQNSSQVEVTNSDIKENSNKMRIILIIIIIFAIICLVV"
     CDS             1882..2715
                     /locus_tag="ctg117_8"
                     /transl_table=11
                     /translation="MILPTMTLTELAKEIQSDYKEVHARWTKFNPKFNKMRLKQTYYPW
                     IWNTEIITKKNNKWFFSFYAQSKKDANVVIPHAYITFRYGGTTWAAYPLKGTNVLLIFS
                     SHFFERYIERFLELNKDEKQYTSLDIIKLFYLRNNHIGCIKPELEDLARGFCEDGMILG
                     EWISDSAALIKTFLSRNELKVNQYTEYYDMFHNWIIQDMFLAHKGYSLSSMEEFDNLPD
                     SYFSPKEWEKFLKLRGNEMWINIAIECSEFRIEHKEEYEKCSNMLQAIMDNRSLE"
     CDS             2727..2876
                     /locus_tag="ctg117_9"
                     /transl_table=11
                     /translation="MITPEELIQDLIDFYGYEVDLSYAINYIDMVGQYAEVDSFHLWLQ
                     DLLI"
     CDS             complement(2959..3789)
                     /locus_tag="ctg117_10"
                     /transl_table=11
                     /translation="MGAIRQTLISKDIISFKKTLNAYIYSIIKMNSNYYNGVSEITYPK
                     IAGLSNISEGIIKTHLSEKDEKGKFVFKDNPLFLGWEYFYVNSKTHIRYKMNTKPENYF
                     ILRNDFILDKNLTPKEKDFLLKFMAICTNNTHYLKASKQDIKDKIGVGKNSTVIDSLIN
                     KGYIVLINGYYIARCKDMPLSRDLERANIYQIIEDFCIGHGVIPPAYDRKKINLILTKY
                     TTVGKSNRQDFKQTLIKKCKHIEQGNYQYLLTALGLYKKEIKPYPQPEKFEIIL"
     CDS             complement(3758..3931)
                     /locus_tag="ctg117_11"
                     /transl_table=11
                     /translation="MIWYKPDNIIFKNRKEAKKYFGTNKYYKIEREKKDIIFIDDHKSI
                     ATNGGNQTDIDK"
     CDS             complement(3918..4037)
                     /locus_tag="ctg117_12"
                     /transl_table=11
                     /translation="MKNEVPAELQFSGTGVTDNSINQMNDNQSILTLKQYDMV"
     CDS             4159..4431
                     /locus_tag="ctg117_13"
                     /transl_table=11
                     /translation="MYICIYHFCSWLAWRQVIGLGCIYSWGYMSGGYEHEKGEPFAQSS
                     LIHFIVISCTIPYPYIRRKRLSQLHIPRWDYPLSILVTHSKCHTV"
     CDS             complement(4310..4945)
                     /locus_tag="ctg117_14"
                     /transl_table=11
                     /translation="MRTHRLPQLIKYIDVRGVNKSMIEFKANLDKLNDFFSIFPKWGIS
                     VTIKLLKELKNDSEAMCNKYFSIISERILNELSARPDGLDIESYKKEIRQLEACFDGIR
                     HHMEDEHFGFFIHEGLNEDMFYVSNNKVYGNLNTMYFYINENSRYAECGDESFILNKLQ
                     DICHELNELRQYDILNALPKLIKDSPNEGYVVDSNAFDECMDKVLYKR"
     CDS             complement(4932..5141)
                     /locus_tag="ctg117_15"
                     /transl_table=11
                     /translation="MNDKQELTFKQLRELALAHHVKDSKTVIGIWAKLNGYSKRRKQKD
                     NKVYTVYIKMSNDKSNKTNNYENA"
     CDS             complement(5150..5482)
                     /locus_tag="ctg117_16"
                     /transl_table=11
                     /translation="MIMNVQFTTSSYFIEDIPVAILNKKDIIKLKMQRYADVKVYLYSF
                     VLPDYMSDEYVSEQLDALASHQLFPYFIVSIANTTICNPRLVANTMNGIVHVVLCFEHE
                     SKTTNN"
     CDS             complement(5746..5919)
                     /locus_tag="ctg117_17"
                     /transl_table=11
                     /translation="MKELTYADIRKMALEHGIKDTRLHIGLWASDRYIKKRKMIQGKMY
                     MVYLPYHKPEQE"
     CDS             complement(6158..8053)
                     /locus_tag="ctg117_18"
                     /transl_table=11
                     /translation="MAHSETSNNGSIKKAETMVSNNEIKQCFVQEITPYYNLVKPKGTK
                     PTMVYFIVRIKKEQVRISTRCKVYPNQWEKNKAKVSKLLPKLESDNNMILNNQIKIYNQ
                     RFDEYKYLVNCGQIEMNKDTLKHYIYKGQIMKEIKEALNIPQTLKKYIYNDISFTDATR
                     ENRIREVEKFESFLNGRVLNSYSELNTKLFREFQEWLIENVEGKNEDGTASPATLNKIV
                     SNLLGSINKYLVANEIISKSQFIDIVVTPIKQTKNDNKIALTEDEIYLLHNYQCETEKD
                     EQIRDLFLLECTTGQRFSDVNKVTNNIIHKDGRTYINLVQDKNKAPIQVDILFEMALEI
                     VQKYDYKLPNISNKLLNERIKIIAQKAGIKGSEELFFDHIDKSKAYTITRERYECVCSH
                     TGRNTFVTMLSLRGWHYHEIGRYTGHKKIETIQHYDKSKVGTKYRVMFEALQKERPELL
                     LKLVTDKVNKETSKEPNNLSTNSLLNDNVKVKPEYYAINSITFDILLDTQFFASKINKA
                     VELQSQVGHLKDGKLCSYDNEIASLISEIEKLSQSSTSDSDVAKQYVKQLSVWKLSDLH
                     DCFRKMIIKCVEIGISRDAIMQFINKALEIGLLDNERFINIKEITTALLDKRNQD"
     CDS             8595..9521
                     /locus_tag="ctg117_19"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETATKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVTTVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             9548..9988
                     /locus_tag="ctg117_20"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVAVLARDLTERIVFHRIIRRNGNILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             10001..10267
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_21"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2e-13,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.3e-16, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             10276..11439
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg117_22"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.9e-46, bitscore:
                     149.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRALYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRHFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRLKGVKDKKARTKK"
     CDS             11462..13132
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 275.5; E-value:
                     1.5e-83)"
                     /gene_kind="transport"
                     /locus_tag="ctg117_23"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHVAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTAAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLLGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVLDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFGYTPDDRPVFSRFSCRFPAGSCIAVVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETSHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNPQASEEAIYQ
                     ALQTATADFVFHLPDGVDSPLSERGGGLSEGQAQRIAIARALLRPGNILLLDEATSALD
                     PDTERLLIKNLRRDCAGKTCIFVTHHPAVAEACESIVRL"
     CDS             complement(13177..14088)
                     /locus_tag="ctg117_24"
                     /transl_table=11
                     /translation="MKPTLFLLAAGMGSRYGGLKQLDGLGPNGETIMDYSIYDAINAGF
                     GKLVFVIRKDFEQDFRDKIISKYEGHIPCELVFQSIDDLPEGFTCPEGRTKPWGTNHAV
                     MMGADVIKEPFAVINCDDFYGRDSFQVMGKFLAALPEGSKNVYSMVGFRIGNTLSESGT
                     VSRGLCGTDSNNLLTSVVERTKIQRMDGEVKYIDDNGEWTATPETTPVSMNFWGFTPDY
                     FAYSAEFFKSFLSDPKNMENLKSEFFIPLMVDKLINDGTATCEVLDTTSKWFGVTYPED
                     RQSVVDKIQALVDAGEYPAKLF"
     CDS             complement(14215..14397)
                     /locus_tag="ctg117_25"
                     /transl_table=11
                     /translation="MKQIALGTGFGLRYDLDFLVFRLDLGIGLHDPYDTGKSGYYNIPK
                     FKDSMALHFAIGYPF"
ORIGIN
        1 acaacacatt tgtttgcaag ttcttccagt gtaatagaat ctgtattggc ttccaagaaa
       61 gtaatacttg gttttgctgt ttcttccaca actaccgttg catcctctgc aaattctcct
      121 aaattgctgt tccttctctg tgccatgact ggcataatct gtaatgcttc cataatctgt
      181 aaattattaa gttgataatt agaaatttct ccatctgaat gccatataaa tgataatgta
      241 cagcactatg gcaaacattg cctttggtgc tgcaatgaac ggtacaacga gtattgcacc
      301 aaccgtcaga attgccttca aatcttccat aagcgataat ttatgattag taatgagtga
      361 attaaaaggg aatgataacc agaaacaaaa agcctcccag ccttgtacgc atgtgcatct
      421 ctgtaataaa tctgtatctg cccgtaatgg ctgttacaga atttcaagcg tttgggactg
      481 gaaggtgatt tcgcatctgg tgttcatttc ccctaaagat acggtgaggg tagttagggg
      541 taacacaaca gaagcgctta agacatacac cagatatgga tatacatgcc aaccgttttt
      601 ctactgccag taattctacc ctatatggct ctgtacctta tatggaaaca cttcccagaa
      661 ctaaaggggg aggggtgtga ttttaagtac ctatattttt gagttgggca taaacacaat
      721 agtaaatcaa ttcatcaata atttagatgg actaattata agaatccaaa atttgctaat
      781 actttattta tttctacctt tatagccatt aataaaacaa taaaatttta ttcatggaaa
      841 agcaaacagc agttagagaa actttattaa aagaatttgc caattgcagt gataaacttt
      901 tcactttagg aataattcgt acagatagct ttactggaga aataggagaa tttattgcct
      961 ccaagtattt taaactaagt ttagctggta aatccacaaa agcatacgat ggagtatgtc
     1021 ctaaaggcta taaatatcaa attaaatcta aagttatatc taacaataat tttactcatc
     1081 atatttctaa tctaaaatat caagattttg actatcttgt agttgtatat tttgatatat
     1141 attacaatcc tatatccata ttaaaaatcc cttctaataa aattaatacg gaagaataca
     1201 ttattggcgc ttcttctgtg ctttcatttt ctcagaatat agctcgatta aaattacttc
     1261 aaaaagaaca agtcgctatc agaaattttg ctcaaagtta cttgaattta caaaaagaag
     1321 ggattattag aagccgtaaa gtagtagggg atattggaga atattatgct tgtaaacgtt
     1381 tgaacctaaa attatctagc aataagaatg agaagggact ggatgcaata ggtcaaggag
     1441 gattaacttt tgaaatcaaa acaaggcgag tatatgatag tgaaagacgg acctctgaaa
     1501 caagaagaat aaacaatcta ataggcaaaa atgcagatta tttaattgtg gtaactttaa
     1561 atcatgcctt tgaatgttct ggaatgtgga taatgccaat gaaaaatata attaatccta
     1621 aatcagccaa tcttaagatt gttaatacaa caataggagt aaagaattta gtaccaagcc
     1681 aaattagttg gttaaacact ggcgagaagt ttgtatcatt taattgcatg gataaacaaa
     1741 atagctctca agtggaagtc acaaattctg atattaagga aaacagcaat aaaatgcgta
     1801 ttattctaat tataatcatt atcttcgcta taatatgttt ggttgtgtga ttattaatct
     1861 caattctaaa tatttattaa tatgatttta ccaacaatga cattgaccga attggcaaag
     1921 gaaattcagt ctgattacaa ggaagtccat gcacgctgga ctaaatttaa tccaaaattc
     1981 aataaaatga gattgaagca aacatattat ccatggatat ggaatacaga gattattaca
     2041 aagaaaaata ataaatggtt cttcagcttt tatgcacaat ctaaaaagga tgctaatgtt
     2101 gtaattcctc atgcctacat tacttttagg tatggaggaa ctacatgggc agcttatccg
     2161 cttaaaggaa caaatgtgtt actgattttt tcttctcatt tctttgaacg gtacattgaa
     2221 cgtttcttgg aactaaataa ggatgagaag caatacacat cccttgatat aataaaatta
     2281 ttttatttac gcaataacca cattggatgt ataaaacctg aattagaaga tttagctaga
     2341 ggtttctgtg aagatggaat gattttaggt gaatggattt ctgattctgc tgcattaatc
     2401 aaaaccttct tatctcgcaa tgaactaaaa gtaaatcaat atacagagta ttacgatatg
     2461 tttcataatt ggattatcca agatatgttc ttagctcaca aaggatattc tctctcatct
     2521 atggaagaat ttgataattt accagattcc tacttctcgc ctaaagaatg ggaaaaattt
     2581 cttaaactaa gaggtaatga aatgtggata aatatagcca ttgaatgtag cgaatttaga
     2641 attgaacata aagaagaata tgaaaaatgt tctaatatgc ttcaagcgat tatggacaat
     2701 cgttctttag aataaaaagt aacattatga ttaccccaga agaattaata caagatttaa
     2761 tagattttta tggttatgaa gtggacttgt cgtatgcgat taactacata gacatggtag
     2821 gtcaatatgc cgaagttgat agttttcatc tttggttaca agatttgtta atatgaatga
     2881 tagaaatgaa caaggtattt acttataatt gagggcataa aaagccccag accttatctg
     2941 ccagtctgga gctttcccct ataatatgat ttcaaatttt tctggttggg gatatggttt
     3001 aatctccttc ttatatagac ctagtgcagt taataaatac tgataattcc cttgctctat
     3061 atgcttgcat ttcttaatta gtgtctgttt gaagtcttga cggttgcttt tgccaacagt
     3121 agtgtattta gtaagaataa gatttatttt ctttctgtca taggctggtg gtataactcc
     3181 gtgtcctata cagaagtcct ctattatttg atagatattg gctctttcca agtctctgga
     3241 taatggcatg tctttgcatc tggcaatata atatccatta ataagaacta tatacccttt
     3301 attgatgagg ctgtcaatta cagtgctgtt tttacctact cctattttat ctttaatgtc
     3361 ttgtttgctt gcttttaagt aatgtgtgtt attagtacaa atagccatga actttagcaa
     3421 gaagtctttt tctttagggg ttagattctt atccagaata aagtcattcc tcaatatgaa
     3481 atagttctct ggcttggtat tcattttata tctgatatgg gttttactgt taacatagaa
     3541 atattcccag cctagaaata gtggattgtc cttaaaaaca aacttcccct tctcatcctt
     3601 ctcacttaga tgtgtcttta taatgccctc tgatatattt gatagtccag ctattttagg
     3661 ataggtgatt tctgataccc cgttataata attgctgttc atttttataa tggagtagat
     3721 ataagcgttc agtgtcttct tgaaactgat aatatcctta cttatcaatg tctgtctgat
     3781 tgcccccatt agtagctatg gatttgtggt cgtctataaa tattatatct ttcttctccc
     3841 gttcaatctt gtaatattta ttagttccaa aatacttctt ggcttccttc ctgttcttaa
     3901 aaataatgtt gtctggttta taccatatca tactgcttta gcgttagaat tgattggttg
     3961 tcattcattt gattaatgga attatctgta actcccgttc cagaaaattg tagttccgca
     4021 ggaacttcat ttttcatata taaggtatgt tatataatag gtatgttact agggtatcat
     4081 tttagggagt gtaccggtat taaaatcggg aatacttatt ggagtctcaa aatagggaat
     4141 aggtaaattc cagactagat gtacatctgt atttatcact tctgttcttg gctcgcatgg
     4201 cggcaggtta ttggacttgg ttgcatatac agttggggat atatgtctgg tgggtatgaa
     4261 cacgaaaagg gagaaccgtt tgcacagtcc tcccttatac attttattgt catctcttgt
     4321 acaatacctt atccatacat tcgtcgaaag cgtttgagtc aactacatat ccctcgttgg
     4381 gactatcctt tatcaatttt ggtaacgcat tcaaaatgtc atactgtctg agttcgttca
     4441 gttcgtgaca gatgtcctgc aatttgttta aaataaaaga ttcatctcca cattctgcat
     4501 agcgtgaatt ttcgttgata tagaagtaca ttgtgtttag gtttccataa actttattat
     4561 ttgagacata aaacatgtcc tcgttcaatc cttcatgaat gaagaatccg aaatgctcat
     4621 cttccatgtg atgtcttata ccatcaaaac aagcttccaa ttggcgaatc tctttcttgt
     4681 aactttcaat atccagaccg tctggtcgtg cagaaagttc attcaagatt ctttctgata
     4741 tgatactgaa atatttgtta cacatggctt cagaatcatt ctttaactct ttaagcagtt
     4801 taattgttac agaaattccc cacttgggaa atatactaaa gaagtcgttc agtttgtcta
     4861 gatttgcctt aaattcaatc attgatttgt taacgcctct aacgtcaatg tacttgatta
     4921 attgtggtag tctatgcgtt ctcatagttg ttagttttat tggatttatc attgctcatc
     4981 ttgatgtaaa cggtgtaaac cttgttatct ttctgcttgc gtctcttgga atagccgttc
     5041 agcttagccc atattccaat aacagtcttg ctgtccttta catggtgggc tagtgcaagc
     5101 tcacgtagtt gcttgaatgt aagttcctgc ttgtcattca taatgttatt caattattcg
     5161 tagttttgga ttcatgctca aagcataaga ccacgtgcac tatgccattc atggtattgg
     5221 cgacaagtct tgggttacaa atggtcgtat tagctataga cactatgaaa tacggaaata
     5281 gctgatgcga tgcaagtgcg tccagttgct ctgatacata ttcatctgac atatagtctg
     5341 gcagcacgaa actgtagagg taaaccttta cgtccgcata ccgttgcatc ttgagcttaa
     5401 taatatcttt cttgtttaaa attgctactg gaatgtcttc aataaagtag cttgaagttg
     5461 taaattgtac attcattatc ataaaattat aaaagtatat aaaatatgaa tcttgatgtg
     5521 gtgagtggcg taaattcaaa tagtagattt cagatgtgcc tcaagtcggt aattcagtgg
     5581 tttcagtgat accgccctta tctcatgttg atgttgcaaa gatactgcac tttggtgagg
     5641 tgccaaaaca ctttgacaac tttcttaaaa cttcgtgtag ggagcttcat ggagtgagga
     5701 tatgtcctct tctgatagct tggaagtaag tttggaactt gaaaactatt cctgctccgg
     5761 tttgtgatac ggcaggtaaa ccatgtacat cttgccttga atcatttttc gtttcttgat
     5821 gtatcggtca gaagcccaaa gcccaatgtg cagccttgtg tccttaatac cgtgctccag
     5881 tgccatttta cgaatgtctg cgtaggtcag ttctttcatt tgaagtggat ttaggtttgt
     5941 agtggtgaat ctgggtgacg agaaactcgg tcatttctga ctttcaatca cagtgcaaag
     6001 gtataaagtc ccgactgcat caccaaacga caagtagaaa ttgtggaata tttgggttga
     6061 gggggcaata aagcaaaaat tctccccata accggagctg ttcggggaga atatgctgtt
     6121 cagccttacc agaaatccta atttcataaa aaacttgtca gtcttgattt cttttatcca
     6181 ataaggctgt agtgatttct tttatattga tgaatctttc attatccaac aagcctattt
     6241 ccaaagcctt attgataaac tgcataattg catccctact gataccaatc tcaacgcact
     6301 tgataatcat tttcctaaaa cagtcatgca agtctgacag cttccaaaca gataactgtt
     6361 tcacatattg ctttgccaca tcagaatcag aagtggaaga ttgggataac ttttctatct
     6421 cgcttataag ggacgcaatt tcattgtcat agctacatag tttcccatct ttcaagtgac
     6481 ctacttgtga ttgtagttca acagccttat tgattttgga tgcaaaaaat tgagtgtcta
     6541 gtaaaatatc gaacgtaatg ctattgattg cataatattc cggtttaact tttacgttgt
     6601 catttaataa tgaattggtt gatagattgt taggttcttt gctggtctct ttattaactt
     6661 tgtcagtaac tagctttagc agtaattctg gacgttcttt ttgaagagct tcaaacatta
     6721 ctctgtattt agtacctact ttggatttat catagtgctg tatcgtttct atttttttat
     6781 gaccagtata acgtcctatt tcgtggtaat gccatccacg taatgataac attgtaacaa
     6841 atgtatttct accagtgtga ctgcaaacgc attcatacct ttctcttgta atagtatagg
     6901 ctttgctttt gtctatatgg tcaaaaaaaa gctcttcact tcctttaatg cctgcttttt
     6961 gagctattat tttaattctt tcatttagta gcttattgct aatgtttggt agtttatagt
     7021 catatttttg tactatttct aatgccattt caaatagtat atctacttga ataggggctt
     7081 tgttcttatc ttgtacaagg ttgatatatg ttctgccatc cttatgtatg atattgttgg
     7141 ttactttgtt tacatcacta aagcgttgtc cagttgtaca ttctaataaa aataaatctc
     7201 ttatttgctc atccttttca gtttcacatt ggtaattgtg taataaatag atttcatctt
     7261 ctgttaaggc tattttatta tcattttttg tctgcttgat aggcgtaacc actatatcta
     7321 taaattgtga tttagaaata atttcattgg ctaccaaata tttatttatt gaccctaata
     7381 agttggaaac tattttattt aatgttgctg gggatgctgt tccatcctca tttttacctt
     7441 caacgttctc aattaaccat tcttgaaact ccctaaacag ttttgtattt agctctgaat
     7501 aactattcaa tactctacca tttaaaaagc tctcaaattt ttcaacctct cttattctat
     7561 tttcccttgt agcgtcagtg aatgatatat cattataaat atattttttt aatgtttgag
     7621 gtatattcaa tgcttctttt atttctttca taatttgtcc tttatagata taatgtttta
     7681 aagtatcttt gttcatttca atttgcccgc aatttactaa atatttgtat tcgtcaaatc
     7741 tttggttata tattttgatt tggttattaa gaatcatatt attatctgat tctagtttag
     7801 gaagtagttt acttacttta gctttgttct tctcccattg attagggtac accttacatc
     7861 ttgtagatat acgcacttgt tcttttttga ttcttactat gaagtaaacc attgttggtt
     7921 ttgtcccttt aggttttaca aggttatagt atggagttat ctcttggaca aaacattgtt
     7981 tgatttcatt gtttgaaacc attgtttcag ctttcttaat agaaccattg tttgatgttt
     8041 cagaatgtgc cataataggg tgttactagg catataggca caaaaaaagg catacagcta
     8101 ttactgtatg ccttattcgt ggagcgtatg agactcgaac tcatcacctc gacactgcca
     8161 gcatccaggt gtccggtgga acgttcatca atttcaaccc ggcaaatccg aatatggacg
     8221 acaatgaatc ctatttggta acaggttacg aggttacccg tgacggcagt gtatatacag
     8281 cagcccacaa agtcaacgat gggaggaaag aatatattgt tggcccaaca agtcaggaga
     8341 accgataagc caaattctaa gaaaggaagc aatatatcct cgcagaccaa acgaagaggt
     8401 atcggaatcg ccttattact atcttttaga tgcggcggac agcggatttt cttttataaa
     8461 tctgcgtcct ccgcgtctaa aaaatgacaa caagacagtt gaaaaatctc tcaaatcttc
     8521 ctcattcaca caaacattca ttatttttct gagtagccca aagtatcatg aataacaact
     8581 aacaatcaaa acatatgaga atacagatat tggattatca agtaggaccg cacaccttcc
     8641 gcatggtgaa accttccgac ttcaatatat tcaaggcgtt gccttcactg attccgttca
     8701 tcacgacaat agacacgacg caaaaagtaa tctttgaaac agagatagac gatgacgaaa
     8761 cagcgacaaa acgaaccata gcgaaaactc ccgatgatat atgtttcaac tgggaagatg
     8821 ccgattgcat cattcgccct ttgccccaca gctcacacct tgtatccatc accccacgga
     8881 aaagcgggaa aaactattgg atggagtgca acgataactt caggcaatgc ttcatccacc
     8941 taccggcctg caggacagaa acaccggctc cggaaaacga aacgaacttc gtactgaaca
     9001 acttcttgat gatgctctat gccttcaatg ccgcccgcca ccatacactg ctgatgcatg
     9061 cctcggttgt cgctactgaa acaggcaaag gctacctctt cttagggaaa agcggcacgg
     9121 gcaaaagtac gcacaccggg ctctggctgc aacagttctc ggactgccat ctactgaacg
     9181 atgacaatcc gatagtacat gtggacagcc tcggcaagca agccactgtt ttcggttctc
     9241 cgtggagcgg aaagacacca tgctatcgga aagaatccat gaccgtaggc gccttcgtcc
     9301 gcttggaaca agcaccgcag aatgaaatag agcaagagag agcagcacat gctttcgcca
     9361 ccctcctccc ctcctgctct tgcctgaagc agaacaagga aatctataac gccattgtca
     9421 ccactgtgac ggaacttgcc acgctggcac ccgtctatca tctgaaatgc ctgcccgacc
     9481 gtgaagcgac ggagctttgc agaaagacgg tagaaggata agttatgaat gatgaactga
     9541 acagccgatg aagaaaagca ttcccaacga gatattgctt cccgaagtgg cgcgtctcat
     9601 caaagagggg catacagtaa ccatcaccgt gcggggcaac agcatgaatc ctttcttagt
     9661 ggaccgccgt gaccgggtga cactgggcga tttcaccaca gaacagctgc aaccgggcgt
     9721 cgccgtactg gcacgcgacc tgacggaacg catcgtcttt caccgcatca tccgtcggaa
     9781 cggaaatata ctcatcctgc aaggcgacgg caacctcgcc cagaccgaag aaaccgacat
     9841 cggacgggta atgggcgtca tgaccgaagc catgcgaaaa gacaaacggt acaccgccga
     9901 cggcaaagtc tggaagctct actcctactg gtggatgaag ctaaaccctg ctcgccgctg
     9961 gctgctcgcc ctgttcagaa gaatataaaa caaaataacc atgaaaatca aacaaggatt
    10021 tatcctgcac cggataggcg atgactacat catcatgcaa gacggctcgt cgaacgtgga
    10081 cttcagcaaa gtcatcagcc tgaaccaaac ttccgccatg ctttggcaag agatagaaaa
    10141 caaagagttc gatacagaca gcgtgacaga agccctgacc agccgctatg atgtagataa
    10201 cgaatcggcc cgtcgcgatg cgcagaagtt tatcgactcc cttgaccgcg aaggaatcat
    10261 agaataagga cggatatgca acacgctttc ttttcattgg tacgctccgg cctgtggggc
    10321 actccggcag accgacaact cttccggtcg gtctcgccgg acgactggga aaccgtgtac
    10381 cgcatggcaa actcacaagc cctgcttgca ctgacttttg acggcataag cagtctaccg
    10441 gccgaactgc gccctccacg cgccctctat ctgaaatggg ctgcccggac tgcacagata
    10501 gaacaagcca acaaacgcct caaccagctt ctgcccgaac tcaataccct ttaccgggaa
    10561 gccgggctgc atcccgtact gctgaaaggg caaggcatcg gcaccaacta ccgcactccc
    10621 ttgcaccggc aatgcggaga catcgacatc tatttaggaa aacaaggaca acccatagcc
    10681 aaccgcctcc tgctgcaaca aggcgccata gtcgagggag aagcgtccga caagcatgcc
    10741 agctacagtt tgaaaggagt acacatcgag aaccaccgca tcatcctccg gctgaacagt
    10801 ccgcttgcca accggcactt tcagcagatt atcagaaaat ggtatccgca ggaaacagac
    10861 tatgccctat tctccgaaac cgggaaagag gactcgaagg ccgtcagtat cgccatacct
    10921 ccggccacct tcaatgcact ttatatcttc ctgcatgcct ttgtacattt cctgaacagc
    10981 ggaatcggcc tgcgccagct atgcgactgg acttgtctgc ttgccaatcg ccacaaagaa
    11041 atagatgcca ccaccctgct tcgccagttg caggacctcg gactattgca tgccgcacaa
    11101 gcattcggct acattgccgt cacccgactg ggattgcccg ccaaccggct tcctttcccc
    11161 ttggaaggca ccaagcagat aggagaacaa ttattggaag acatcctgtc taccggtaac
    11221 ttcgggcaac atgataaccg catcaagcca cgccccaaag gatattgggc aggaaagtgg
    11281 tacaccttct gccgcgccac ccgacgctgc aacgaactgc gtcaatttgc accgtacgaa
    11341 gcactctggt atcccgtgac tctgataggg ggaacgatag ctatacaaat aaaccgatta
    11401 aaaggagtaa aagacaagaa agcaaggaca aagaaataaa agaacccgga aaataaaagg
    11461 aatgaaaaag caacagaagg acaaaaaagt gaaaaaggac agacgtgaaa aacttaggta
    11521 tattcgagag gtatctgccg aacaacgcgg acgtatcctg ctaagttgcc tcaccggcat
    11581 tctgggcgtg gcctttgccc tagcctttat ctatgcaacc aaacgggtga tagacaccgc
    11641 taccggaata acagacgaca acctgacgca tgtcgccgtt ctcaccgttg tcctgctgac
    11701 tgcccaatta ctgtgcggag ctgctgacac ttggataagt acccgtatgc agatagagac
    11761 gggcaacgcc cttcgccacc gcctcttctc gcgcttactg caaagccgct ggaacgaatt
    11821 ggagcgtttc cataccggag acgtagtgaa ccgggtagaa caagacaccg ccgccatcgt
    11881 cacattgctc acctcttctg tcccggcatt catcgtcacg agtatacaac tgctggcagc
    11941 ctttctattc ttctactttt tagacccttc actgccatgg ctgattgttg ccatcctgcc
    12001 cgtctttcta ttaggcagcc gtttctatat gcgacgaatg aaacgctata cacatgatat
    12061 tcggaacagt gacggtcgca tccagtccgt catacaagag agcctgcaac atcgcatagt
    12121 gattaaaaca ttggaacaag gcgaacggca tctggacaaa ctcgatgact tgcaagacat
    12181 gctccacagc caagtcatgg gacgtacccg tttctcgctt tccgcccaca tgttagtggc
    12241 ccttgccttt tccggcggat acctcacggc ttttctttgg ggagccgttc acctcagcgc
    12301 aggctgtatc accttcggaa cgatgaccgc ctttttgcaa ttggtaggaa aagtccagcg
    12361 tcccgtgctc gacctctcac gcctgatacc ttccgtagtc aatgccctta ccgccataga
    12421 ccggctattg gaattggaaa gactgccggc agaagcggac ggtgacagca tattcctcgc
    12481 ctctaccccg gaactggaac tgaaagacgt gacttttggc tacactcccg atgaccgtcc
    12541 ggtattcagc cgcttctcct gccgtttccc cgccggtagc tgcatagctg tagtcggaga
    12601 aacaggaaaa ggaaagacaa cgctcatccg gctattgttg gcactggcaa cgccacaaga
    12661 gggacagata ctcttgatac ccgccaaaca tccacttgaa accagtcata ccgtctctcc
    12721 gcaaacccgc aagaacttcg tatatgtccc gcaaggcaat acccttttca gcggaactat
    12781 ccgtgacaac ctgctgatgg gaaacccaca agcttctgaa gaagccatat atcaagccct
    12841 gcaaaccgcc accgccgact tcgtcttcca ccttcccgac ggcgtagact ccccactcag
    12901 cgaacgaggt ggtggactca gtgaaggaca agcccaacgc atcgccattg cccgcgctct
    12961 gctacgcccc ggaaacattc ttcttttaga tgaagccact tctgccctcg accccgacac
    13021 ggaacggctg ttaataaaaa acctgcgcag agactgcgca ggcaaaacat gtatcttcgt
    13081 cacccaccat ccggcagtag cggaggcatg cgaatctatt gtccgattat aatcagagaa
    13141 tgagccccaa cgggtatctg cctttggtta acaaactcag aacagcttcg caggatactc
    13201 gcccgcatcc accaaagcct gaatcttgtc gactacactc tgacggtctt caggataagt
    13261 cacaccgaac cacttgctgg ttgtatcgag cacttcgcag gtagcagtgc catcgttaat
    13321 cagcttatcc accatcagtg ggatgaagaa ttcgctcttc aggttctcca tgttcttcgg
    13381 gtcgctcaag aagctcttga aaaactctgc actgtaagca aagtaatcgg gagtaaagcc
    13441 ccagaagttc atgctgaccg gagtcgtctc gggagtggca gtccattcac cgttatcatc
    13501 gatgtacttc acctcaccgt ccatacgctg aatcttggta cgttctacta cggaagtcaa
    13561 caagttgttt gaatccgttc cgcacaaacc acgagatacg gtaccgcttt cgctcaatgt
    13621 attaccgatg cggaagccta ccatggaata tacatttttg gaaccttcgg gaagggctgc
    13681 aagaaatttg cccattacct ggaaggaatc acgaccgtag aaatcgtcgc agttgataac
    13741 agcaaacggt tcctttatta catcggcacc catcattaca gcatggttgg ttccccaagg
    13801 tttggtacgg ccttcggggc aagtgaagcc ttcgggaagg tcatcaatgg actggaatac
    13861 cagttcgcac ggaatatggc cttcgtattt ggaaataatc ttgtcgcgga aatcctgctc
    13921 aaaatcttta cggataacaa acacaagctt gccaaagcct gcattgatgg catcgtaaat
    13981 agaataatcc atgatagttt cgccattcgg gcccagtccg tccaattgtt tcaagccacc
    14041 ataacggctg cccatgccgg ctgccaataa gaataaagtt ggtttcatac ttagttatta
    14101 tttaaaaagg ttagtgtatc acagttgata acggttgcaa atgtacaaaa atttatggct
    14161 gacagaaggg agttttagtt cattctttac cactatccgt tcaaaaaggt acatttagaa
    14221 cggataaccg atggcaaaat gcaacgccat gctgtccttg aacttgggaa tattataata
    14281 ccccgacttc ccggtatcat acggatcatg cagcccgata cccaagtcca gacgaaaaac
    14341 aagaaagtcc aaatcgtaac gcaagccaaa tcccgtgcct aaagcaatct gtttcggga
//
