LOCUS       c00375_gnlPro..        13616 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IFFMHHBN_375.
ACCESSION   c00375_gnlPro..
VERSION     c00375_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:42:25
            Original ID  :: gnl|Prokka|IFFMHHBN_375
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13616
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13616
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3616]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3616
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..13616
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13616
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..484)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg375_1"
                     /sec_met_domain="Rnf-Nqr (E-value: 4.5e-57, bitscore:
                     183.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETALGMSAA
                     VAFVLTIATIVTFLIQKYVLDAFDLGYLQTITFILVIAALVQMVEIILKKVSPSLYQAL
                     GVFLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTALGFGLALTLFAGLREQMSL"
     CDS             complement(572..1234)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg375_2"
                     /sec_met_domain="Rnf-Nqr (E-value: 5e-71, bitscore: 229.3,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNNLLIPQLPKLWIHSALNEKGVEDMNNFKVMMNGIIKENPTFV
                     LLLGMCPTLGTTSSAINGMGMGLATMFVLICSNVVISAIKNLIPDMVRIPSFIVVIASF
                     VTLLQMIMQAYVPALYATLGLFIPLIVVNCIVLGRAEAFAAKNNPVASLFDGLGMGLGF
                     TIALTLLGAVREFLGTGKIFNLSILPEEYGMLVFVLAPGAFIALGYLIALINSMKKN"
     CDS             complement(1173..1838)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg375_3"
                     /sec_met_domain="FMN_bind (E-value: 6.5e-24, bitscore:
                     75.5, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLESSLKNMLLVLTGVTAISVALLAYVNELTKEPIAQANAKTL
                     SDAVSAVVPGFDNDPIAEKKMQEVNGVQYSVYPATKGGEYIGAAVEAVAMGFGGELKVL
                     VGFDAEGKIIDYSLLSHVETPGLGSKAADWFKKGNKGDITGMNPGEAALTVSKDGGKVD
                     AITASTITSRAFLNAVNAAYAAYAGQETADGTTGATQKNVEQPADSAAPEAVDTLSAK"
     CDS             complement(1835..2827)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg375_4"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 5.5e-119,
                     bitscore: 387.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLIVSLSPHVHGGDSVKKNMYGVLIALIPAFLVSLYFFGLGAL
                     IVTATSVAACLFFEWAIGKFLMKKETTTITDGSAIITGVLLAFNLPSNLPIWIIILGAL
                     FAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPAVGQLTAYTDATTAATPLA
                     IMKGVINGAPGMSLSDLPGAFDLLIGNNGGCLGEVSALALLLGLFYMLWKKIITWHIPV
                     SILVTVFVFSGIMYLVNPELYVSPVVQLLSGGLMLGAVFMATDYVTSPMSHKGMLIYGV
                     CIGLLTVIIRLFGAYPEGMSFAILIMNAFTPLINTYVKPKRFGEVAKKK"
     CDS             complement(2834..3616)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg375_5"
                     /sec_met_domain="Fer4_10 (E-value: 3.4e-09, bitscore: 27.9,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4.7e-16, bitscore: 49.6,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.7e-23, bitscore:
                     74.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5e-05, bitscore: 14.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASSYAGIEVVP
                     LKVQYPQGGEKQLIDAVISRQVAAGALPISTGAVVQNVGTAFAVYQAVQKNKPLFERVI
                     TVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVNTDVPTAKG
                     SSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERVEKEDIMSC
                     IECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             3629..3970
                     /locus_tag="ctg375_6"
                     /transl_table=11
                     /translation="MFQHQLMVGSQIRFALYGVDDDTLCLECRRRTQLDLRRKACTAQT
                     YDTCISDFLHDFLGGQTAFLHQRFGTVNGFFPFIPFYVNEYSRLGVTAGIDNRVNLSDF
                     PADRRMNGC"
     CDS             4474..4575
                     /locus_tag="ctg375_7"
                     /transl_table=11
                     /translation="MPRYKPCVLRPPCPCLHTVRKYDVISCLEDGFQ"
     CDS             4556..5107
                     /locus_tag="ctg375_8"
                     /transl_table=11
                     /translation="LRTDFNNRFRTSLGTSSTSRTLFLIHFGKSGLRIHVDSIELAGSH
                     TVAASQTAITTTRFTTIERSRNGTTLGAIVLVHTRTVGTSSITSHHRNHRFGSSGIQAQ
                     NLGNLCHDGLSTHRTKFTIQRTCLYASICKSATTGVTTSTAICLGKHLCYLGNPRIFIH
                     GEFLGSHVKNSGRYQRYNSQ"
     CDS             complement(5172..5396)
                     /locus_tag="ctg375_9"
                     /transl_table=11
                     /translation="VTGELSMGVMAVLFAFIFPFLILIISLFVFMAIWNDELRSALCSL
                     ALLIPYYYILWLNKSRMGKKFSFSVRPMN"
     CDS             complement(5822..7204)
                     /locus_tag="ctg375_10"
                     /transl_table=11
                     /translation="MAQNTLDTASKNSGQETTAKADTLPDIMKEYMILKLKPEGMGYRL
                     DTVSILYERYIGVLDYLNDPTTPERYIPSNPNYYRLFLPLTYYYAPMRRLSKVDWHFQV
                     PDTVPALTREMLPFDTLSFTSKDRANKLVDRTLLNTYVNCPNLVVMTEKEVMKGKIFKD
                     NIEKEVSSKPSVVKLFAQENMVGVKEEADVIIHKPNWWVTGGNGSLQITQNYISDNWYK
                     GGESTNAVLANLQLFANYNDREKVQWENLLDAKLGFSSAPSDEFHNYLVSTDQLRLYSK
                     LGIQAASKWYYTITTEFKTQFCNGYKANSEELVSAFFAPADWSSSIGMDYKLKKQKFSL
                     SVFMAPLTYMLRYVGNKGVNEVSFGLEEGKCVKHNFGSQIQPTLSWTIIPSITLDSRLD
                     FQTSYEWTRIEWENTVNFVLNRYLSTKLYVHARYDDSAKPTEGDSYFQVKELLSFGINY
                     KW"
     CDS             complement(7294..7500)
                     /locus_tag="ctg375_11"
                     /transl_table=11
                     /translation="MPRAYTACRSGCALLPSVHVELKKRKIIKKRGSRESFDETIIKKY
                     DFIEESPSCLFLMAFLCFLNILS"
     CDS             complement(7513..7608)
                     /locus_tag="ctg375_12"
                     /transl_table=11
                     /translation="MEDEMIPLPNEEATPPVTKIYFVSPTTILFY"
     CDS             7616..9151
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg375_13"
                     /sec_met_domain="GATase (E-value: 1.7e-54, bitscore: 175.6,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLQARGYKVTIQKFDPYINIDPGTLNPYEHGECYVTVDGHEADLD
                     LGHYERFLGIQTTKANNITTGRIYKSVIDKERRGDYLGKTIQVIPHITDEIKRNVKLLG
                     NKYKFDFVITEIGGTVGDIESLPYLESIRQLKWELGKDALCVHLTYVPYLAAAGELKTK
                     PTQHSVKELQSAGIQPDVLVLRTEHELSTTLRKKVALFCNVDENAVVQSIDAPTIYEVP
                     ILMQRQGLDVTILKKMGLPVGDTPGLGPWRAFLERRHKAEETAPLHIALVGKYDLQDAY
                     KSIREALSQAGTYNDRKVSVDFVNSEKLTDENVAEALKGMAGVLIGPGFGERGVAGKFV
                     AIKYARTHDIPTFGICLGMQCIAIEFARNVLGYADANSREMDEKTSHNVIDIMEEQKSI
                     TNMGGTMRLGAYECVLQKGSKAYEAYGTEHIQERHRHRYEFNNSFKDAYEAAGMKCVGI
                     NPESDLVEIVEIPALKWFVGTQFHPEYSSTVLHPHPLFVAFVKAAIENENEKK"
     CDS             complement(9228..9419)
                     /locus_tag="ctg375_14"
                     /transl_table=11
                     /translation="LTGVEEEGSGVNACFRSAFVGQGCFRLGFQVGFALLHLGYGVVVT
                     LLCFQLLLAGTAQKAETY"
     CDS             9570..11036
                     /locus_tag="ctg375_15"
                     /transl_table=11
                     /translation="MNFLFYNKKETIQTEDYYFTAVNRTDSTVTMRLSADSNSYIDFTY
                     RMHNDTYLIDFTIQAVNMEGKLAATNNYVDIEWSQRARQIEKGYTYENRLAELTYKITG
                     EGTDYLSANKNDEKEVPERLDWIAFKNQFFSSVFLADADFEKTKLSSKMETQGSGYIKD
                     YSAEMSTKFDPAGKEPTQLFFYFGPNHYKTLTALDKGRDEKWELNRLVYLGWPLIRWIN
                     KWFTINIFDWLSSWGLSMGIVLLFMTLIVKAVVFPATWKTYMSSAKMRVLKPKIDEINK
                     KYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLIQFPILMALFMFVPSAIELRQQSFL
                     WADDLSTYDAFINFPFHIPFLGSHLSLFCLLMTVTNILNTKYMMQQQDTGANPQMAAMK
                     WMSYLMPIMFLFILNDYPSGLNYYYFISTLISVVTTLIMRKTTNEEALLAQLEANKKDP
                     KKMKKTGFAARLEAMQKQQEQMMKERQNKK"
     CDS             11139..12470
                     /locus_tag="ctg375_16"
                     /transl_table=11
                     /translation="MQTKYTYKQIWLIAYPILISLLMEQMIGMTDTAFLGRVGEVELGA
                     SAIAGVFYMVIFMVAFGFSIGAQILIARRNGERQYKEIGDLFYQGIYFQVGMATVMFLL
                     SYCFSPIILKRIVASEHIYEAATSYLHWRVFGAFFSFSAVMFRAFFLGTTQTKTLTLNS
                     IVMVLSNVVFNYILIFGKFGFPALGIAGAAIGSSLAELVSLLFFILYTRSRIDCRKYGL
                     DRIPKFRLDVLKRMLNVSFWTMIQNFFSLSTWFLFFLYVEHLGERSLAVTNIVRNVSGI
                     LFMVLMAFASTCGSLVSNLIGAGHSDCVAGTIRQHVRIAYVFVLPLALLFALFPKLILG
                     IYTDIPDLQDAAVHSLWVMCSTYLFLVPANVYFQAVSGTGNTRTALGMELATLVIYTAY
                     ITYIILILQLDVAICWTSEMVYSSFILIFCWLYIKRGNWQGRKI"
     CDS             complement(12935..13174)
                     /locus_tag="ctg375_17"
                     /transl_table=11
                     /translation="MEVNENRGRLCRKKLQGKIRKKKNHQKEKDITGSVKRANHNKGSM
                     IVSDPTELVQPGGNNHSSRFVRLCVGACFIHGAG"
     CDS             complement(13206..13535)
                     /locus_tag="ctg375_18"
                     /transl_table=11
                     /translation="MCCAICLKFAVAVISSLFLIFLFLMRIQELRELSFKLSYLPLVYP
                     TFFLCVFLSHRSFSFRVLEKVGIRECKVFRSKYYPQGWRFLPKTGGLTLLSRPIPELPL
                     RPERK"
ORIGIN
        1 ccaggctcat ttgctcgcgc aggcctgcaa acagtgtcag tgccaagccg aaaccaagtg
       61 ccgtggagaa tgcataaacc actcccgtca gcaaatcata atctttttgg ataacaagga
      121 tagccacacc gagaatacag cagttggtag taatcaacgg caggaacacg cccaaggctt
      181 gatacagaga aggagaaact ttcttcagga taatctctac catctgcacc aatgcggcaa
      241 tcaccaggat aaaggtaata gtctgcaaat agcccaaatc aaaagcgtcg agcacatact
      301 tctgaataag gaatgtcacg atagtggcga tggtgagcac aaatgccacc gctgccgaca
      361 tgcccaatgc agtctccact ttcttggaaa ctcccaagaa cgggcaaatt cccaagaatt
      421 gcgacaatac gatgttgttt acaaagattg ccgagataaa tatcaatata tattccataa
      481 tcattaaatt aagaattaaa aactaaaaat taaaagccca gcagcttacc gccgatacgt
      541 tctcaatttt ttcattttta atttttcatt attaattctt cttcatactg ttgattaaag
      601 caatgagata gcccaatgca atgaatgcac ccggagcaag gacaaatacc aacatgccgt
      661 attcttcggg aaggatactc aagttgaata tcttgccggt tcccaggaac tcacgcacgg
      721 cacccagtaa tgtcagtgca atggtaaagc ccaagcccat gcccagaccg tcgaacaagg
      781 aagccaccgg attgtttttg gcagcaaatg cctcggcacg tcccaatacg atacagttta
      841 caacaatcag cggaatgaac aggcccagtg tagcgtacaa tgcaggaacg taagcttgca
      901 ttatcatctg caacagtgtc acaaatgatg ctatgactac aatgaatgaa gggatacgca
      961 ccatatcggg aatcagattc ttgatggcag aaatcaccac attggaacat atcagcacga
     1021 acattgtagc cagtcccata cccataccgt taatggcaga ggaagtggta cccagtgtag
     1081 gacacatacc cagcaggagt acaaacgtag gattctcttt gataatcccg ttcatcataa
     1141 ctttaaaatt attcatatct tctactcctt tctcatttag cgctgagtgt atccacagct
     1201 tcgggagctg cggaatcagc aggttgttca acattctttt gagtagcgcc ggtagtgccg
     1261 tcggcagttt cctgaccggc ataggcagca taagccgcat tcactgcatt caaaaaagca
     1321 cgtgaggtga tggtagacgc tgtaatggca tctactttac caccgtcctt gctcactgtc
     1381 aatgcagctt cacccggatt catgccggtg atgtcacctt tattgccttt cttgaaccag
     1441 tcggcagcct tggaacccaa ccccggagtt tccacatgcg acaacaagga gtagtcgatg
     1501 attttgcctt cagcatcgaa accgaccaac actttcagct caccgccaaa acccatggca
     1561 acagcttcca cagcagctcc gatatattct ccgcctttgg tggcaggata tacagaatac
     1621 tgtactccgt ttacttcctg catcttcttc tcggcgatgg ggtcattgtc gaagcccgga
     1681 accaccgcac ttacggcatc gctcaaggtc tttgcattgg cctgcgcaat gggctccttc
     1741 gtcaattcgt ttacataagc cagcaacgct acggagattg cggtaacgcc cgtaagtacc
     1801 agcaacatat tcttcaagga tgattctaac tttttcattt cttcttcgct acctccccaa
     1861 agcgtttagg tttaacatag gtgttgatga gcggagtgaa cgcattcata atcagaatgg
     1921 caaacgacat accctccgga tatgcaccga acagacggat gatgacagtc agcaggccga
     1981 tgcaaacacc ataaatcagc atacctttgt ggctcatcgg agaagtcacg tagtccgtag
     2041 ccataaagac agcacccagc atcagaccac cggacaacaa ctgtacgacc ggggatacat
     2101 aaagttccgg attgaccaga tacatgatac cggagaacac gaataccgtc accagaatag
     2161 ataccggaat gtgccaggtg atgattttct tccacaacat gtagaacaaa ccaagcagca
     2221 gcgccaaggc actcacctca ccgagacatc ctccattatt acctatcaga aggtcgaaag
     2281 ctcccggaag gtcgctcagg gacatgcccg gagcaccatt gatgacacct ttcataatag
     2341 ccagcggcgt agcagccgtc gtggcatccg tataggctgt caactggcct acagccggcc
     2401 atgtcgtcat ctgcacgggg aatgaaagca acaggaatac acgtcctgcc agtgcagggt
     2461 taaagggatt gcaacccaaa cctccgaagg acatcttgcc taccccgatg gcaaacaagg
     2521 caccaaggat gataatccag atgggcaggt tggaaggcag gttaaaggcc agcaacacac
     2581 cggtaatgat ggcagagccg tcggtgatgg ttgtggtctc ttttttcatg aggaatttgc
     2641 cgatggccca ttcaaagaac aagcaggctg ctacggaagt ggccgtaaca atcagcgcac
     2701 ccagtccgaa aaagtaaagc gaaacgagga atgccggaat caatgcgata agcacaccgt
     2761 acatattctt cttcacgctg tcaccgccgt gaacgtgggg cgaaagggat acgattaatt
     2821 tattcatact tcgttatttt ttagcttgac gtgcacggat catcgctcct accttaccct
     2881 tacccaagcg gatataatcc agcatcggac ggttggaagg acaagtgaac tggcatgaac
     2941 cgcattctat acacgacata atgtcttctt tctctactct ttcaaaatct ccgtgggccg
     3001 aaacggtagc cagcagatac ggctccaacc ccatcgggca ggctcccacg cacttggcac
     3061 aacggataca aggctgtacc tcgccgcgct tggcttcctt ctcgttcata atcagaatac
     3121 cggagcttcc tttggctgtc ggtacatccg tatttaccag agctttaccc atcatcgggc
     3181 caccgccgat aatcttgccc gtatcttcgg gcagaccgcc gcaagcttca atcagctgct
     3241 tcatcggcgt accgatacgt gccaggaaat tggacggctt tgccaacgac ttaccagtca
     3301 cggtaatgac acgctcaaac agaggtttgt tcttctgtac ggcctggtaa acggcaaatg
     3361 cggtacccac attctgcacc acagctcccg tggagatagg cagcgcaccg gctgcaacct
     3421 ggcgactgat gacagcatca atcaactgct tttcaccacc ctgcggatat tgtaccttca
     3481 agggtaccac ctcgatacct gcatagctgg aagcaacctt cgtcatcagc tggatggcat
     3541 cgggcttatt gttctcaatg ccgatgaatg ccttgttcac ctttaccgcc ttcatcagaa
     3601 tggatacacc taccataatt tcttccgcat gttccagcat cagctgatgg tcggcagtca
     3661 gatacggttc gcactctacg gcgttgatga tgacacactc tgccttgaat gcaggaggag
     3721 gacacaactt gacctgcgta ggaaagcatg caccgcccag acctacgata cctgcatcag
     3781 cgattttctt cacgatttcc tcggaggtca gactgcattc cttcaccaac gtttcggaac
     3841 ggtcaatgga ttcttcccat tcatcccctt ctacgtcaat gaatatagca ggcttggcgt
     3901 aaccgctggc atcgacaatc gtgtcaatct tagcgacttt cccgctgaca gacgaatgaa
     3961 tggctgctga tacaaaaccg ccgggctcgg caatctttgt acccactttc acaacatcac
     4021 ctttggcaac gataggcttg gcaggagcac cgatgtgctg tcccagcaag atagcggcct
     4081 tggccggaat ctctgccttg atgataggct gatgtgctga aagtttattt tcgtgtggat
     4141 ggactccacc aattgaaaat gtcttcaaca tacaattctg tatttttagt cgtttattta
     4201 ctttattaat tcatacctca acttgggaag tctaaacctc cgctttagga gtctcaacct
     4261 cagctttagg aactgcaacc tttacttggg gagctgtatc gtcagccttc ggtttgcgcg
     4321 gcgggaagtt gagggcaatg attgtgtttt gcggacaagc ttcctcgcac ttgcgacagg
     4381 atttgcactt attggggtca atgtaagcca gattgttttc cagcgtgata gcctcgaacg
     4441 gacaaacctt cacacacttg ccgcaaccga tacatgccac ggtacaagcc ttgcgtgcta
     4501 cggccccctt gtccttgttt acacactgta cgtaaatacg acgtgatttc ttgccttgag
     4561 gacggatttc aataatagat ttcggacaag ccttggcaca agctccacaa gccgtacact
     4621 tttcctcatc cacttcggga agtccggtct ccggattcat gtggatagca tcgaactggc
     4681 aggcagccac acagtcgccg catcccagac agccataact acaacccgtt tcaccaccat
     4741 agagagaagc cgcaatggca caactcttgg cgccatcgta ttggttcaca cgaggacggt
     4801 tggcacaagt tccattacat ctcaccaccg caaccatagg ttcggcagca gcggcatcca
     4861 agcccagaat ctcggcaatc tttgtcatga cgggctgtcc acccaccgga caaagtttac
     4921 catccagcga acctgccttt acgcaagcat ctgcaaatcc gctacaaccg gggtaaccac
     4981 atccaccgca atttgcctgg ggaagcacct ctgctacctg ggcaatccgc ggatcttcat
     5041 acacggcgaa tttcttggaa gccacgtaaa gaatagcggc cgataccagc gctataactc
     5101 ccaatgaaat cactgcaatc agaattacat tcataaatta gttgtttatt aattatttgt
     5161 tttattatta gttagttcat cggtcgtacg gagaatgaga acttcttacc catccgcgac
     5221 ttgttcagcc acaatatata ataataaggt ataagaagtg ccagcgaaca aagtgcagaa
     5281 cgcagctcgt cattccagat agccataaag acaaacagtg agattatcag aataaggaaa
     5341 ggaaatataa aggcaaacag aactgccatc actcccattg aaagttcgcc cgtcacccat
     5401 acacggtcac cgggctggta ggatgcggca ttggcatcgg ccacatcgac aagtttctct
     5461 ttcgtatccg cagaggtaca atgccccttg acactacacg aagcgcacgc tgaagtctgg
     5521 atgattctca cttggagatg agaaccgttt atgttttcca caataccttg atgttttata
     5581 gtattcgcca ttttgcaaag tgtgcattac aaatcgcggc aaatttacgc attatttgtg
     5641 aactgcaaac ctttcctatg cattttctgt gttcgtaaac gtgctttttc tatgttttta
     5701 tgttttttca cctgccacag actacaaaaa gacaaaaaac agacggtctg tcaaggaaaa
     5761 acagaccgtc tgactaacca aaacagataa tctgttcact ccgaacagac catttgttta
     5821 tttaccattt ataattgata ccgaaactga gcaattcttt tacctgaaaa tagctgtccc
     5881 cttccgtcgg cttggcactg tcgtcatagc gggcgtgcac atagagcttg gtggaaagat
     5941 agcggttcag cacaaagttc accgtgtttt cccattcgat acgcgtccac tcataactgg
     6001 tctggaagtc caggcgggaa tccagcgtaa tggaaggaat gatggtccac gaaagtgtag
     6061 gctgtatctg cgaaccgaag ttatgcttca cgcacttgcc ctcctcaaga ccgaaactca
     6121 cttcattcac acccttattc cccacatagc gcagcatgta cgtcagcgga gccatgaaaa
     6181 cggacaagct gaatttctgc ttcttcaact tgtagtccat accgatactg cttgaccagt
     6241 ccgccggagc aaagaaagcc gaaaccagct cttcactgtt ggccttgtag ccattgcaga
     6301 actgggtctt aaactcagtc gtgatggtat aataccactt ggacgcagcc tgaataccca
     6361 gtttactgta cagccggagt tggtcggtac ttaccagata gttatgaaac tcgtcggaag
     6421 gtgcggagct gaagcccagc ttggcatcga gcagattttc ccactgcacc ttttcacggt
     6481 cattatagtt ggcaaacaat tgcaggttgg caagcacggc gttagtgctc tcacctccct
     6541 tgtaccagtt gtcggagata tagttctggg taatctgcaa cgaaccgttt ccacccgtca
     6601 cccaccagtt gggcttgtgg ataatcacgt cggcttcctc cttcactccc accatattct
     6661 cttgtgcaaa cagtttcacg acggacggct tggaagaaac ctccttctct atattatcct
     6721 tgaatatctt ccctttcatc acctccttct cggtcattac aaccagattg ggacaattca
     6781 catacgtgtt cagcagcgta cggtccacca gtttgttggc tcggtccttt gaggtgaaac
     6841 tcagtgtgtc gaacggcaac atctcgcgcg tcagggcagg caccgtatca ggcacctgga
     6901 aatgccagtc caccttggaa aggcgtctca tgggggcata ataataggta aggggaagga
     6961 acaacctata gtagttcgga ttggaaggta tataacgctc cggagtcgtg gggtcattca
     7021 aataatccag cactccgata tacctttcat ataatatgga aacagtatcc agcctgtacc
     7081 ccataccttc cggtttcaat ttcagaatca tgtattcttt cattatatcc ggcaaggtgt
     7141 cggctttggc agttgtttcc tgtccactgt tcttcgaggc ggtatccagc gtattctgtg
     7201 ccatcaccga cgaagaaatc atcgtagcaa ttaaccaaaa tgcaatgtgt ctattcttca
     7261 taatgcccta aagtctatgt ttcgagcgca aatttagctt aaaatgttta gaaaacatag
     7321 aaaagccata agaaaaaggc aagaaggact ttcttcgatg aaatcgtatt ttttaataat
     7381 tgtttcatcg aaactttctc tacttcctct tttttttata attttgcgct ttttaagttc
     7441 tacgtgtact gacgggagca gtgcgcaccc tgaacgacaa gccgtatagg ctcttggcat
     7501 tagattaaac aattaataaa ataatatagt tgtgggagaa acaaagtata ttttcgtcac
     7561 cggtggtgtt gcctcttcat taggtaaagg tatcatctca tcctccatcg gtaaattgct
     7621 gcaagcaaga ggttacaagg taaccatcca gaagtttgac ccgtacatca acatcgaccc
     7681 gggtacactg aacccttatg aacacggcga atgctacgtt accgtggatg gccacgaagc
     7741 cgacctcgat ttgggccatt acgaacgctt cctgggcatc cagaccacca aggccaacaa
     7801 tatcacgacc ggacgcatct acaaaagcgt catcgacaaa gagcgccggg gtgactatct
     7861 gggaaagacc atccaggtta ttccccatat tacagacgaa atcaagcgta atgtaaaact
     7921 gttgggaaac aaatacaaat tcgactttgt tattaccgaa attggcggta cagtgggtga
     7981 catcgagtct ctgccctatc tggaaagcat ccgtcagctg aagtgggaac tgggaaaaga
     8041 cgccttgtgc gtacacctta cttatgtccc ctacctggca gctgccggtg aactgaagac
     8101 caagcccacc cagcactccg taaaggaact gcaaagtgcc ggtatccaac ctgatgtcct
     8161 cgtactgcgt acggaacacg agttgagtac caccctgcgc aagaaagtgg ctctgttctg
     8221 caatgtggac gaaaatgccg tggtgcagag catcgacgcg cctaccatct acgaggtgcc
     8281 catcttgatg cagcgccagg gactggacgt taccattttg aagaaaatgg gacttcccgt
     8341 cggcgacact ccgggactgg gaccgtggcg cgctttcctc gaacgccgtc acaaagccga
     8401 agagactgcc ccgctgcaca tcgcattggt gggcaaatat gacttgcagg atgcctacaa
     8461 gtccatccgc gaggcccttt cacaagcagg aacctacaat gaccgcaagg tatcggtaga
     8521 cttcgtgaac agtgaaaagc tgactgacga gaatgtggca gaagccctga aaggcatggc
     8581 aggcgtactt atcggtccag gcttcggcga acgcggcgtt gccggcaagt tcgtagccat
     8641 caaatatgcg cgtacgcacg acatccccac cttcggtatc tgtctgggta tgcagtgtat
     8701 cgccatcgaa tttgcccgta acgtactggg ttatgccgat gccaactcac gcgagatgga
     8761 cgaaaagaca tcgcacaatg tcatcgacat catggaagag cagaagtcca tcaccaatat
     8821 gggtggaacc atgcgtctgg gtgcctacga atgtgttctg cagaaaggca gcaaggcata
     8881 cgaggcatat ggtaccgagc atatccagga acgtcaccgt caccgctacg agttcaacaa
     8941 cagcttcaag gatgcctacg aagcagcagg catgaagtgt gtgggtataa accccgaatc
     9001 ggatctggta gaaattgtcg aaatacccgc attgaagtgg tttgtcggta cccagttcca
     9061 tcccgaatac agcagtacgg tattgcatcc gcacccgctg ttcgtagcat tcgtgaaggc
     9121 cgccatcgaa aatgaaaacg aaaagaaata atttgtaata agtaatttgt aatcaacaaa
     9181 gaatggataa aaataccatc acaggtcttg ttctgatagc gatattgtta gtaggtttca
     9241 gctttctgag ccgtcccagc caggagcagt tggaagcaca gcaacgttac tacgactcca
     9301 tagcccaggt gcaacagcgc gaagccgact tgaaagccaa ggcggaagca gccctggcca
     9361 acgaaagcgg agcggaagca agcgttgact ccactgccct cttcttcgac gcccgtcaag
     9421 gaaccaactc gcaggtaacc atccagaaca acctggcaga aataaccgta gatacaaaag
     9481 gcggacgcat agcttcggcc acgctgaagg aatacatggg acaagacaag acgactcccg
     9541 tcacactgtt cagcggcaac gacgcttcca tgaatttcct cttttacaac aagaaagaga
     9601 ctatccagac ggaagactat tatttcaccg cagtaaaccg tacggacagt accgtcacca
     9661 tgcgtttgtc ggcagacagc aacagctata tcgactttac atatcgcatg cacaatgaca
     9721 catacctgat agactttact atccaggcag tcaatatgga aggtaagctg gcggctacca
     9781 acaattatgt ggacatcgag tggtcacaac gtgcccgtca gatagagaag ggttacacct
     9841 acgagaaccg tctggctgaa ctgacttaca aaatcaccgg agagggtacc gattatctgt
     9901 ccgccaacaa gaacgacgaa aaggaagttc cggaacgcct ggactggatt gctttcaaga
     9961 accaattctt ctcttcagta tttttggcag atgccgactt tgaaaagacc aaactgagtt
    10021 ccaagatgga gactcaaggc agcggctaca ttaaggacta ttctgcggag atgagcacga
    10081 agttcgaccc tgccggcaag gaacctaccc agctgttctt ctacttcggc cccaatcact
    10141 acaagactct gaccgcactc gacaaggggc gtgacgagaa gtgggagctg aaccgtctgg
    10201 tctatctggg ctggccgctc atccgctgga taaacaaatg gttcaccatc aacatcttcg
    10261 actggttgtc cagttggggg ttgagcatgg gtatcgtact gttgtttatg acgttaatcg
    10321 taaaagctgt agtattcccc gcaacgtgga aaacctacat gtcatccgcc aagatgcgcg
    10381 tactgaaacc gaaaatcgac gagataaaca agaagtaccc caagcaggaa gatgccatga
    10441 agaagcagca ggaagtgatg ggcctctaca gccagtacgg agtcagtccg atgggcggat
    10501 gtctgccgat gctgatacag ttccctatct tgatggcctt gttcatgttc gtgccgagtg
    10561 ccattgaact ccgccagcag agcttcttgt gggcagacga cctttccact tacgatgcgt
    10621 tcatcaactt cccgttccat atcccgttcc tgggaagcca cctcagcttg ttctgcctgc
    10681 tgatgacggt taccaacata ttgaacacga agtacatgat gcagcaacag gatacgggtg
    10741 ccaatccgca gatggctgcc atgaagtgga tgtcatacct gatgcctatc atgttcctct
    10801 tcatattgaa cgactatcct tcgggattga actattacta cttcatctct acgttaatca
    10861 gtgtggtaac aacgctcatc atgcgcaaga caaccaatga ggaagccctt cttgctcagt
    10921 tggaagccaa caagaaagac ccgaagaaga tgaagaaaac cggtttcgcc gctcgtctag
    10981 aagccatgca gaaacagcag gaacagatga tgaaagagag acagaacaaa aagtagtaag
    11041 actaccgttc aagatattct tttgcagaaa gccggacaat gacatttgcc cggctttctt
    11101 atccttacac caacgaaaaa attcacagac tctaaattat gcagactaaa tacacctaca
    11161 aacaaatctg gctcatagcc taccctatcc taatcagcct ccttatggag cagatgatag
    11221 gtatgacgga caccgccttc ctcggacgtg taggcgaagt cgagttggga gcatctgcca
    11281 tcgccggtgt cttctatatg gtcatcttca tggttgcctt cggtttcagc atcggggcac
    11341 agatactcat tgcccggcgc aacggcgaac ggcagtataa ggaaatcggt gacttgttct
    11401 atcagggcat ctatttccaa gtcgggatgg cgacagtcat gttcctgctg tcctattgct
    11461 tttcgccgat tatcctgaaa cgcatcgtag cctcggaaca tatctacgaa gcagccacca
    11521 gctacctgca ctggcgtgta ttcggtgcct tcttctcgtt cagcgcagtc atgttccgtg
    11581 cctttttctt gggaaccacc cagaccaaga cactgacact gaactctatc gtcatggtgt
    11641 tgagcaatgt tgtattcaac tatatcctga ttttcggtaa attcggtttt cctgcactcg
    11701 gcattgccgg agccgccatc ggctcctcat tggccgagct ggtttcgctg ttattcttca
    11761 tcctctatac ccgtagccgt attgactgcc gcaagtacgg gctggaccgt attccgaagt
    11821 tccggctgga cgtattgaaa cggatgctga acgtctcttt ctggaccatg atacagaatt
    11881 tcttctccct ctccacctgg ttcttgttct tcctttatgt ggagcatctg ggagagcgct
    11941 cgctggcagt gaccaacatt gtccgcaatg tgtccggcat actgttcatg gtactcatgg
    12001 catttgcctc tacctgcggt tcattggtca gcaacctcat cggtgcaggc cactccgatt
    12061 gcgtggcagg cactatccgg caacatgtac gcatagccta cgttttcgta cttccgctgg
    12121 cattgctttt cgcgctgttc cccaagctga ttctgggaat ttataccgac atacccgacc
    12181 tgcaggatgc tgccgtgcat tcgctttggg tgatgtgctc cacctatctg ttcctggttc
    12241 ctgccaatgt ctatttccag gcagtttccg gaaccggcaa tacgcgtact gcattgggca
    12301 tggagctggc aacgctggtc atctacacag cctatatcac ctacattatt ctgattctgc
    12361 aactcgacgt ggccatctgc tggacctcgg aaatggttta ttccagcttt attctcattt
    12421 tctgctggct atatatcaaa cgtgggaatt ggcaaggaag gaaaatttag tatctttgca
    12481 ttgagaagtt acgaaaagag tgtaatttat tggaaatgag cgtaggttaa ttgctcttga
    12541 tagtaatagg ttacgattta gttagttatc tactgcatta tccttctgcg cgttgcgtaa
    12601 ccttcaaaga actcttcgta tgcaaaagta gctatttaat tcgagatttt gatataaact
    12661 cccgtttttt atcccctcat tcataagaat tttccgtaaa agcggtattg tccgtcggca
    12721 caccattgcc caaaacgagt ttggaacaaa cgtgtgccga ctaccgcata gctggagaaa
    12781 agggcattgc ctcacgccta aacgatgttt agacagatga agcaatgccc ctttcttttg
    12841 cgcctatgcc aagaggtgct tttacgggtt ttcaaatgat ttttcttttt tcgctgtctc
    12901 ttttgccgga agcggaaagt gaatgcagag tgtgtcagcc tgccccatga atgaaacagg
    12961 cgcccacaca cagccggaca aaccgggaag aatgattgtt gccacccggc tgaacaagtt
    13021 ccgtcggatc ggaaacaatc atacttcctt tgttgtggtt tgcccttttc acgcttccgg
    13081 tgatgtcttt ttccttttgg tgattctttt ttttacggat tttcccctga agtttttttc
    13141 tacacaatct gcctctgttt tcgtttacct ccattttgcg cctttcagta agccgcatca
    13201 gtcagtcatt ttcgttctgg gcgcaaaggt aattccggga ttggacggga aagcaaggtc
    13261 aagcctcctg ttttcggtaa aaatctccag ccctgcgggt agtattttga ccgaaaaacc
    13321 ttgcattccc taatccctac cttttcaagc acccgaaacg aaaacgaccg atgcgacaga
    13381 aagacgcata aaaaaaatgt cggataaacg agaggcagat aagatagttt gaaactcaac
    13441 tccctcagct cttgaatccg cattaaaaac aaaaaaatca aaaacagcga agatatgacg
    13501 gcaacggcaa atttcagaca aatggcgcaa cacatcgggt tggcgatatg cggcttgatg
    13561 atgcgcaccg ccttcggggt gttcggcatc ctttggggca tcatcagaga gattgt
//
