LOCUS       c00108_gnlPro..        13655 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JELDGKEC_108.
ACCESSION   c00108_gnlPro..
VERSION     c00108_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:00:56
            Original ID  :: gnl|Prokka|JELDGKEC_108
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13655
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..816
                     /locus_tag="ctg108_1"
                     /transl_table=11
                     /translation="EPVFFAYPDNSELDAIVMKYTAREPEYNFVAKLDGFGHTFWIIDE
                     DKDIARITELFGEMPALYIADGHHRSAAAALVGAEKAKQNPDHKGDEEYNYFMAVCFPA
                     NQLTIIDYNRVVKDLNGLTEEQFVERLTKNFVVEEKGSAIYKPGALHNFSLYLGGKWYS
                     LTAKPGTYDDNDPIGVLDVTISSNLILDEILGIKDLRSDKRIDFVGGIRGLGELKRRVD
                     SGEMKVALALYPVTMKQLMDIADTGNIMPPKTTWFEPKLRSGLVIHKLD"
     protocluster    1..13655
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5124:10185]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5125..10185
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..13655
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13655
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             989..1570
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg108_2"
                     /sec_met_domain="HAD_2 (E-value: 1.3e-09, bitscore: 28.2,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDRDEPVRRLIEIGVKDADGLIDPYEQKGVFQDLETGKIGVEEFC
                     RYLRKHTGKDLSYEDICWAWFGFIGGVPQYKLDYILKLREKYQVYLLSNTNPIIQLEWA
                     QTKEFTPAGRPLNDYFDKLYLSYEIGVTKPDREIFDRMVLDSGIRPEETLFVDDGKNNI
                     VVGQELGFHTYQPLNGEDWRGRLDEILSKS"
     CDS             1609..3990
                     /locus_tag="ctg108_3"
                     /transl_table=11
                     /translation="MTNTTLNLEELLCGVNELVDTLWIVTLGNEKVEIVKDSMTPEREG
                     ECLDYTELCQTYIQEYVYPADLGKWEEILSLNSLRQMAASGVANKKFDMRFCNDLLGFE
                     WHEAFIRILKDKSGIPDRVILFSRYVNHCRKAQIVEAAVQTEYDYVVYIEANTNSYVMY
                     TSNRESGTPVPPIASNDYEKEVAEFHHKYVPEDQRDELTRNLSLDHVLSILQNSREYVL
                     FCQVMENGVFRDKKLRFSFFDKERNILLLTRTDIMEVREEERQRQLLQDALQVAKSANQ
                     AKSDFLSRMSHDIRTPMNAIIGMTTIASMHIDDRERIVDCLKKIMVSSKLLLNLINEVL
                     DMSKVESGHILLTDEEFDMGELLQSVITMVQTSVSQKFQDFRVHLFQIKHEKLIGDVQR
                     IQQVLLNLLSNAIKYTPDYGKITLEIREKPIKNGNYGLFEVTVIDNGIGIKPDFLHKVF
                     EPFERAEDATLRNIQGTGLGMAISRNIAHMMNGEILVESEYGKGSVFTFTMQLKLQDQG
                     CFEDDHLRDLPVLVVDDDIVCCENACMRINEIGMKGEYAISGEEAIGKVERAHHLNDDY
                     FAVILDLKMPGMDGIETATRIRKVVGRDIPIIILSAYDCPHFEEIAQRAGVDGFISKPL
                     MKSKLFYLMKSFAIKQEEKEEETEKPQYPFGNFEGKRILLVEDNSLNREIATVLLEETG
                     AVVEEAENGLVAVNMVKNSSPGYYDLVFMDIQMPVMNGYDSTRHIRALERPDIKSMPII
                     AMSANAFAEDIKLCKESGMNEHIAKPIDFGKVLEILEKYL"
     CDS             complement(4059..5099)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg108_4"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 8.6e-50, bitscore:
                     159.7, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKILVAGGTGYIGSHTTVELQNAGYEVVIIDDLSNSNIEVLDG
                     IEKITGIRPEFIQLDLKDKEGTRKALEAHPGIKGIILFAASKAVGESVQQPLKYYRNNI
                     VTLVNLLEMMPEFNIEGIVFSSSCTVYGQPDPENLPVTENAPIKPAMSPYGNTKQINEE
                     IIRDTIHAGAPFKSIILRYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAMGIRKELSV
                     FGDDYDTADGSCIRDYINVVDLAKAHVIAMDRMLENKSDEHIEIFNLGTGNGVSVLELI
                     NTFEQTTGVKVPHKIVGRREGDIEKVWANPEHANKVLGWTAKETLADTLQSAWNWQKRL
                     RERGIQ"
     CDS             complement(5125..5697)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 9.5e-66, bitscore:
                     210.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFIAAVFVNNVVLAQFLGICPFLGVSKKVETAAGMGAAVT
                     FVLTIATIVTFLVQKYILDAFGLGFMQTISFILIIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKEYNLLESVVYAISTAIGFALALIIFAGIREQLAMTHVP
                     EGMKGTPIALITAGLLAMAFMGFSGIV"
     CDS             complement(5710..6294)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 6.9e-69, bitscore:
                     221.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNLKILMNGIITENPTFVLLLGMCPTLGTTSSAINGMSMGLATM
                     FVLICSNIVISALKNVIPDLVRIPGYIVVIATFVTVVQMCMEAFVPALYASLGLFIPLI
                     VVNCIVLGRAEAFAAKNGVVPSAFDGIGIGLGFTMALTLLGACREFLGTGKLFNVTLMP
                     EEYGSLIFVLAPGAFIALGYLVAIVNKLRKA"
     CDS             complement(6312..6896)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_7"
                     /sec_met_domain="FMN_bind (E-value: 4.6e-26, bitscore:
                     81.1, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSLTGICLVAGAILAGVNQFTAGPIAVAKATALEEAIKAVAPE
                     FDNKPTEDVYMAVSSDGDSLKIYPAKKGGQVVGGAVESNTKKGFSGEIRVIVGFDMDGK
                     ILNYSVLQHAETPGLGAKMQEWFRADKNKQSVLGRTIPDGGLKVTKDGGDVDAITAATI
                     SSRAFLDAVNRAYSAFAGVDGLTGATSTDNK"
     CDS             complement(6929..7897)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_8"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 6.2e-117,
                     bitscore: 379.8, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLYVSPSPHIHGGDSISKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTVVSVLACMIFEYLIQRFLMKKEPTLCDGSAILTGVLLAFNLPSNLPVWIIIIGAL
                     AAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTTWPVVDALNVFPMTYTDAQTGA
                     TVLSLMNEGVTELPSYGNMLVGAMGGSLGEVSAVALILGLLFMLWKKIITWQIPVSILA
                     TVFVFTGIMHLVNPVQYASPFVHLLSGGLLLGSIFMATDYVTSPMSKNGMLVYGVGIGI
                     LTTVIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     CDS             complement(7910..9241)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_9"
                     /sec_met_domain="Fer4_10 (E-value: 8.4e-10, bitscore: 28.6,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 3e-17, bitscore: 52.1,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.4e-50, bitscore:
                     161.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 2.7e-32, bitscore: 100.7,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.7e-05, bitscore: 15.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRTFRIGGIHPPENKLSAGKKITALATPKQVIIPLSQHIGAPAQ
                     AVVKKGDLVKVGTLLAKAGGFVSANIHSSVSGKVNKIDNALDASGYKRPAIYIDVEGDE
                     WEETIDRSETLVKECALSSKEIVDKIAASGIVGLGGATFPTQVKLMPPPGNKAEIVIIN
                     AVECEPYLTSDHSLMLEKGEQILVGVTILMKAVNVNKAVIGIENNKPDAIAHLQKLAVN
                     YKGIEIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNVGTAYAVYEAVQKN
                     KPLFERVVTITGKAVANPSNFLVRMGTPISCLIEAAGGLPENTGKIIGGGPMMGKALIS
                     AEVPVCKGSSGVLLLTKEESVRKPIRDCIRCAKCVGVCPMGLNPTLLMNATEFQNWELA
                     EKNYITDCIECGSCSYTCPANRPLLDQIRLGKGKVMGIIRSRKS"
     CDS             complement(9253..10185)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 35.6; E-value:
                     3.5e-11)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_10"
                     /sec_met_domain="Fer4_7 (E-value: 7.3e-12, bitscore: 35.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_9 (E-value: 6.8e-11, bitscore: 32.1,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.9e-09, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 2.1e-09, bitscore: 27.1,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.5e-10, bitscore: 30.5,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.3e-06, bitscore: 18.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILIAVISLGAIGAVGAVFLYAASKKFEVYEDPRIAQVQEVLPGA
                     NCGGCGYPGCAGFAGACVKADSLDGLLCPVGGGPVMAKVATILGKEAGTTEPMVAVVRC
                     NGTCQARPRTNSYDGTKSCAIASTLYGGETNCSFGCLGYGDCVNACAFDAIHINPATGI
                     AEVDEEKCTSCGACVKACPKSIIELRKKGPKSRRIYVSCVNKDKGAAARKACANACIGC
                     GKCAKECPFEAITVTNNVAYIDYTKCRMCRKCVAVCPTGAIHELNFPPRKEAAPAPKAE
                     TVKPAPKAEATVKPEAAPKATSEEKTNLN"
     CDS             complement(10195..10611)
                     /locus_tag="ctg108_11"
                     /transl_table=11
                     /translation="MSESINHTGFVEKIDGDTVFVRITQQSACSGCHAQSMCSASEKKD
                     KIIEVPDRSGRFRINEEVIICGQNSMGLQAVLLAFVIPLVIVVGAIVIGTNLQWDETTS
                     GLTGLSLLLPYYCILYLMRDKLKRRFIFTLKKLN"
     CDS             complement(10713..12254)
                     /locus_tag="ctg108_12"
                     /transl_table=11
                     /translation="MMKRHGVYALLLLSLIGGSAYSQENQLVTGTIVQRPAQQVVSDDT
                     IPAINLSEEELDNIVDIRKQFEKQNKTYSAPLAPSTNLLRFLKKDELEISDEAMYWARL
                     VRDASTIFDNTMTFRDTVIVNPLFMPIVFRGDYLPENLIFYNFDSLKERTPYDNLYRAD
                     SIFKDLERNKQFEEMAYKYVQNNYPTYFRYSERDLPNEVIKPKFIKKNIYEDLPIKVEA
                     DANFEDVDAPARFIPERRYWISAFESAIQFSQNYVSENWYKGGSSNLNLFTKNNLKYDY
                     KKDKVQVTNELEFKASVYTAPKDTLRNYKIGDDVFRIHSNVGYQAFNKWYYTFDAEFKT
                     QFFTNYQENEHIKQAAFLAPFSINFGLGMKYELEKQFTDKHKKIKFSTNLAPISYTYMY
                     TTQEIDYSRHGFKKNEETGEFNNKLSQIGSTIRADLAFDFNRNVSWQSRLYFFTTYGDH
                     TIGEFENTLVLAISRFFSTRIYFHLRYDDGVEKTEDNKSYFQLNELLSFGFNYKW"
     CDS             12675..13655
                     /locus_tag="ctg108_13"
                     /transl_table=11
                     /translation="VADTKYIFVTGGVVSSLGKGIISASLGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLNVQTTRANNITTGRIYQSVINKE
                     RKGDYLGKTVQVVPHITDEIKRNVKLLGSKYKFDFVITEIGGTVGDIESLPFIESVRQL
                     KWELGKNCLCVHLTYVPYIAAAKEYKTKPTQHSVKQLQELGIQPDVLVLRTEHELNANL
                     LRKVALFCNVAEDSVIQSIDVPTIYEVPLVLQRQKMDEVVLRKVGMEVGPTPELKPWKE
                     FLALKSTATDTVKIGLVGKYVELQDAYKSIDESLLQAAIYNHHKLD"
ORIGIN
        1 gagccggtat tcttcgctta tcccgacaac tcagagttag acgctatcgt aatgaaatat
       61 acggctcgtg agcctgaata taatttcgtg gcgaaattag acggtttcgg ccatacgttc
      121 tggattatcg atgaggataa ggacatcgcc cgcatcacgg agttattcgg ggagatgcct
      181 gcgttgtata ttgccgacgg acatcatcgt tccgccgccg ctgctttggt aggagcggag
      241 aaggccaagc aaaacccgga tcataaggga gacgaggagt ataactattt catggctgtt
      301 tgcttcccgg ccaaccaatt gaccattatc gattacaacc gtgtggtaaa agacttgaac
      361 ggcttgaccg aggaacaatt cgttgagaga ttaacgaaaa acttcgtggt agaggagaag
      421 ggctctgcta tttacaaacc gggtgccttg cacaatttct ccctgtattt aggagggaaa
      481 tggtattctt tgaccgctaa gcccggtacg tacgatgaca atgacccgat aggcgtattg
      541 gatgtcacga tctcttcgaa cttgattctg gatgagattt taggcattaa ggatttacgt
      601 tcggacaagc gaatcgattt cgtgggaggt atccgtggcc tgggtgaatt gaaacgccgt
      661 gtggatagcg gtgagatgaa ggttgccttg gctttgtatc ccgttacgat gaagcaattg
      721 atggatatcg ccgatacggg taatattatg ccgccgaaga cgacgtggtt cgaaccgaag
      781 cttcgctccg gtttggtgat ccataaattg gattaagtct tatatacata aatatagctt
      841 tggattgggg tataatcgtt gaagattata ccctttttta tccttgtaac ctagatatac
      901 ggaataaatt gtatctttag gacttaaata gtatcgcaat gggtaaaata aaaaatatag
      961 tattcgatct gggggcgtta tcatagattt ggaccgggat gaacctgttc gtcgtttaat
     1021 agagattggg gtcaaagatg ccgatggatt gatagatcct tacgaacaaa aaggggtttt
     1081 tcaagatctg gagaccggaa agatcggagt agaggagttt tgtcgctatt tacggaagca
     1141 tacgggtaaa gacctttctt atgaggatat ttgttgggct tggtttggct tcattggtgg
     1201 cgttccccaa tataaattgg actacatatt aaaactccgt gagaaatatc aagtctattt
     1261 attgagcaat acaaatccga tcatacagct tgaatgggca cagacaaaag agtttacgcc
     1321 ggcgggccgt ccattaaatg attatttcga taaattgtat ctctcttatg aaatcggtgt
     1381 cactaagcca gatcgtgaaa tttttgatcg catggtcttg gattcaggaa tcagaccaga
     1441 ggaaacatta tttgtagatg atggtaagaa taatatcgta gtggggcagg aactggggtt
     1501 ccatacctat cagcctttga atggagagga ttggagaggg aggctcgatg aaatactctc
     1561 aaaatcatag gatctctatt cctcttaatt aaatctatat cattgaaaat gacaaatact
     1621 actttaaatt tggaagaact actctgtggt gtaaacgagc tagtcgatac gctttggatc
     1681 gtcacattag gtaatgaaaa ggttgagata gtcaaagatt cgatgactcc cgaaagggaa
     1741 ggagaatgtt tggattatac agaactttgc cagacttaca ttcaagaata tgtatatcct
     1801 gcggatttag ggaaatggga ggagatctta tccttgaatt cattgcggca aatggcggct
     1861 agcggcgtag caaataagaa gttcgacatg cgtttctgta atgatttgtt gggttttgag
     1921 tggcatgagg cttttattcg tatcttgaaa gataagagtg gaattccgga tcgtgtcatt
     1981 cttttcagcc gctatgtgaa tcattgtcgc aaggcacaga tcgtagaggc tgccgttcag
     2041 actgagtatg attatgtcgt ttatatagag gcaaatacga atagctatgt catgtatact
     2101 tccaatcgtg aaagtgggac gccggtcccc ccgatagcga gtaatgacta tgaaaaagag
     2161 gtagccgagt tccaccacaa atatgtgccg gaggatcagc gagatgagtt aacccgaaat
     2221 ctttccctag atcatgtctt atctatctta caaaattccc gtgagtatgt cttgttctgt
     2281 caggtgatgg agaatggcgt ttttagggat aagaagttgc gttttagctt tttcgataag
     2341 gagaggaata tacttctttt gacccggacc gatattatgg aggttcgtga ggaagagcgg
     2401 caaaggcaat tacttcaaga tgccctacaa gtggctaaat cggcaaatca ggctaaatcg
     2461 gatttcttat cccgtatgag ccatgatata cgtactccga tgaatgccat tatcggtatg
     2521 accactatcg ccagtatgca tatcgacgat cgggagcgta tagtggattg cttgaagaag
     2581 attatggttt cttccaaatt gttattgaac ttgatcaatg aggtcttgga tatgtctaag
     2641 gtagagagcg gacatatttt gctgacagac gaggagttcg atatgggcga gttattgcaa
     2701 agcgtaatta ctatggttca gacttcggtc agtcagaagt ttcaggattt ccgggttcac
     2761 ttgtttcaaa tcaaacatga aaagctgatt ggcgatgtgc aacggattca gcaagtattg
     2821 ttgaatttgc tgtcaaacgc cataaagtat acgccggact atgggaaaat aacacttgag
     2881 atacgggaaa agccaattaa aaatggtaat tatggtttat ttgaggttac ggttatagac
     2941 aatggtatcg ggataaagcc ggatttctta cacaaggttt tcgaaccatt tgaacgtgcg
     3001 gaagacgcaa ccttgcggaa tatacaagga accggcttag gcatggcgat aagccgtaat
     3061 atcgctcata tgatgaatgg tgagattctg gtggagagtg aatatggcaa aggttccgtt
     3121 tttacattta cgatgcagtt gaaattgcag gatcaagggt gttttgagga tgatcattta
     3181 agggatttac cggttctcgt ggtagacgat gatatcgtgt gttgcgagaa cgcatgtatg
     3241 aggattaacg agatcggtat gaaaggtgaa tatgccattt ctggtgagga ggctatcggg
     3301 aaagtagaga gggcacatca tcttaatgat gactattttg ccgttatcct tgatctgaaa
     3361 atgccgggaa tggatggaat cgagaccgct acccgtatcc gaaaagtcgt tggccgggat
     3421 attccgatca ttattctttc cgcttatgat tgtccgcatt ttgaggagat agcccaacga
     3481 gccggtgtcg atggattcat aagtaagccg ttgatgaaat ccaagttatt ttatttgatg
     3541 aaaagtttcg ctatcaagca agaggaaaaa gaggaagaga cggagaagcc tcaatatcct
     3601 ttcggtaact ttgagggtaa gcggatcttg ctggtggaag ataatagctt gaatagggaa
     3661 atagcgactg tgttactaga agagaccggt gcggtggtag aggaggcgga aaatggcctt
     3721 gtcgcggtga atatggtaaa aaactctagt ccgggatatt atgacttggt atttatggat
     3781 atccagatgc cggtcatgaa cgggtacgac tctactcgcc atattcgggc attagaacgt
     3841 ccggatatca agtccatgcc gataatagcc atgtctgcga acgcatttgc ggaagacatc
     3901 aagttgtgta aagaatccgg aatgaatgag catatcgcta agccgatcga tttcgggaaa
     3961 gttcttgaga tcttagagaa atacttgtag atataaggat ataaaaaagg ccatatctta
     4021 gctaagcgct atcagatacg gcctcttttt tgtgttattt actggatgcc acgttctctc
     4081 aaacgtttct gccagttcca tgcggattgc agggtgtcgg ctaaagtctc cttggcggtc
     4141 cagcctaata ccttattcgc gtgctccgga ttggcccata ccttctcgat atcaccttca
     4201 cgacggccca cgatcttgtg cggaacctta acgcctgttg tctgctcgaa ggtattgatc
     4261 agttcaagga cagaaacacc attgccggta cctaggttga atatctcgat atgctcatca
     4321 gacttattct caagcatacg gtccatagcg attacatgcg ctttcgccaa gtctacgaca
     4381 ttgatatagt cacggatgca agagccgtct gccgtatcat aatcatcgcc gaatacgctt
     4441 aattccttgc ggatacccat agccgtctgt gtcaagtacg ggatcaagtt ctggggaaca
     4501 ccatttggca actcgccgat ctctgcgctt gggtgagcgc ctatcgggtt gaagtagcgc
     4561 aagatgatac tcttgaaagg cgctcccgca tggatcgtat cccggataat ctcctcgttg
     4621 atctgcttcg tgtttccata aggagacata gcgggtttga tcggggcatt ctcggttacc
     4681 ggcaagttct ccggatccgg ttgtccgtat accgtacaag aggaagagaa tacgatacct
     4741 tcgatattga attcaggcat catctccaac aagttcacca aagtgacaat attattgcga
     4801 taatacttca aaggctgctg tacggattct cctaccgcct tgctagcggc gaacaagata
     4861 atgcctttga tgcccggatg agcttccaat gccttgcgag taccttcctt atcctttaga
     4921 tccaattgga taaactccgg acggatgccc gtgattttct cgataccatc gagcacctcg
     4981 atattcgagt ttgacaaatc gtcgataatg actacctcat atccggcgtt ctgcaattct
     5041 actgtggtgt gtgagccgat ataaccggtt ccgcccgcta ctaaaatctt ctttttcatt
     5101 ctagtgttca tttagataag tttgttatac gatacccgag aatcccataa aagccatagc
     5161 tagcaaaccg gccgttatca aggcgatagg agtgcctttc atgccttccg gaacatgcgt
     5221 catggctagt tgctcccgaa tacccgcgaa gataatcaaa gctagcgcaa atccaatagc
     5281 ggtcgagata gcatatacca cagattctaa taaattatac tctttttgga ttacaaggat
     5341 cgccacaccc aagatacagc agttcgtggt gatcaacgga aggaatacgc ccaacgcctg
     5401 gtaaagggcg ggagagacct tcttcaatat gatttccacc atctgaacca aggcggcgat
     5461 gatcaagatg aaactgatcg tctgcatgaa ccctaatccg aaagcgtcca atatgtattt
     5521 ttgcacgagg aatgtaacaa tcgtggcgat cgtaagcacg aacgtaacgg cggctcccat
     5581 gcctgcggca gtctccactt tcttagatac ccccaagaac ggacaaattc ccaagaactg
     5641 tgccagtaca acgttattaa cgaatacggc ggcgataaat atcaatatat attccatatg
     5701 atccgtttat tatgctttac gcagtttgtt tactattgct accagataac ccaaggcgat
     5761 aaacgctccc ggagccaata cgaagatcag cgaaccatat tcctcgggca tcaaggttac
     5821 gttgaataac ttaccggttc ccaagaactc acggcaagcg cccagcagcg taagagccat
     5881 cgtaaagccc agtccgatac cgattccgtc gaaagcggat gggactacgc cgttcttcgc
     5941 agcgaaagcc tcggcacgtc ctagtacgat acagtttacc acgatcaacg ggataaataa
     6001 tcccaagcta gcgtataaag ccgggacgaa cgcttccatg cacatctgca ctacggtcac
     6061 gaacgtcgcg atcacaacga tatatccagg gatacgcacc aagtcgggga ttacgttttt
     6121 caaggcggaa atcacgatat tcgagcaaat caatacgaac atcgtagcca atcccatact
     6181 catgccgttg atggccgaag aggtcgttcc caaggtagga cacataccta acagtaatac
     6241 aaatgtcggg ttctccgtga tgataccatt catcaatatt tttagattac tcattgttct
     6301 gtcctccctt tttatttgtt atcagttgaa gtggcacccg ttaatccgtc tacgcctgcg
     6361 aatgcgctat acgcacggtt cacggcatcg aggaacgcac ggctggagat ggtcgctgcc
     6421 gtgatagcgt ccacgtcgcc accatctttt gttactttta agcctccgtc cggaatcgta
     6481 cgtcccaaga cactttgctt gttcttgtcc gcacggaacc attcttgcat cttggctccc
     6541 aagcccggag tctcggcgtg ttgcaatacg gaatagttca agatcttgcc atccatatcg
     6601 aaacctacga taacccgtat ctcaccgcta aagccttttt tcgtattact ctctacggct
     6661 ccgccaacga cttgtccgcc tttcttggca ggataaatct tgagggaatc accatcggag
     6721 gagacggcca tatagacgtc ctcagtcggt ttgttgtcga actcgggagc aacggcttta
     6781 atcgcttcct ccaaggcggt cgctttagct accgctatag ggccggcggt aaactggttc
     6841 actccggcta ggatcgcccc tgctaccaag caaatgcctg ttagtgaaag gagcatattg
     6901 ggtaatgttg attttaattt tgccatgctt actttcctcc gaaatgttta ggtttgatat
     6961 agctgttgat tagcggagta aatgcgttca tgatcaggat agcgaacgac ataccttccg
     7021 ggtaagaccc gaacaaacgg atcaccgtgg taaggattcc gattcccacg ccgtagacaa
     7081 gcattccgtt cttgctcatc ggcgaggtta cgtagtcggt cgccataaag atggagccta
     7141 ataacaaacc gccggataat aagtgaacga acgggctggc gtattgtacc ggattcacca
     7201 agtgcatgat gcccgtgaat acgaatacgg tagccaagat ggataccggg atctgccaag
     7261 tgatgatctt tttccatagc atgaataaaa gaccgaggat caaggccacg gcgctcactt
     7321 caccgagact acctcccata gctcctacaa gcatgttccc gtaagacgga agctcggtca
     7381 cgccttcgtt catcaacgac aataccgttg cgccggtctg ggcatccgta taagtcatcg
     7441 ggaaaacgtt caaggcatct accaccggcc aagtcgtcat ctgtgccggg aaggagatca
     7501 ataagaatac acgtccgact aacgccggat tgaaaatatt attacctaat ccaccgaaag
     7561 acatcttgcc gatgccgatc gccgccaacg ctccgataat aatgatccag accggaaggt
     7621 tggaaggtag gttgaaggcc agcaatacac ccgtcaggat agcggagcca tcgcaaaggg
     7681 tcggttcctt tttcatcagg aatcgctgga tcaaatactc gaatatcata caggccagaa
     7741 ccgatacgac cgtaacgatc aacgctccca gaccgaagaa ataaagggat accaagaaag
     7801 ccgggataag ggcaatcagt acaccataca tatttttgct tatgctgtcg ccaccatgga
     7861 tgtggggcga gggcgatacg tataaattat tttccatgtt gctcttgttt tatgactttc
     7921 tagaccggat aatacccata acttttcctt tacccaaccg gatctgatcc agcaacggac
     7981 ggttggccgg acaggtataa ctacacgacc cgcactcgat acagtcggtg atatagttct
     8041 tctccgccaa ttcccaattc tggaattccg tggcgttcat caatagggta gggtttaatc
     8101 ccatcgggca gacacctacg catttggcgc aacggatgca atcccggatc ggcttgcgga
     8161 cagactcctc tttcgtcagt aataaaacgc cggagcttcc tttgcaaacc ggcacctcgg
     8221 cgctgatcaa cgctttaccc atcatcggtc cgccaccgat aatcttaccc gtattctcgg
     8281 gcaggccacc tgcggcctcg atcaagcaac tgatcggggt tcccatacga accaagaaat
     8341 tggaaggatt agctaccgcc ttacccgtga tcgtcaccac acgctcgaac aacggtttgt
     8401 tcttttgtac cgcctcgtaa acggcataag cagttcctac gttctgtacc acggcacccg
     8461 ccgagatagg aagcgcaccg ctttttacct gacggcgaat aacggcgtcg atcaattgtt
     8521 tctcgcctcc ttgcggatat tgtaccttaa gcggcatgat ctctatacct ttataattta
     8581 ccgccaactt ttgcagatgg gcgatagcgt ccggcttgtt attctcgata ccgatcacgg
     8641 ccttgttcac gttgaccgct ttcattagga tcgtgacacc gactaggatt tgctcgcctt
     8701 tctccagcat caacgaatgg tcggaagtaa gataaggctc acactccacg gcgttgatga
     8761 ttacgatctc tgccttgttt ccgggaggcg gcatcaattt cacctgcgta gggaaagtcg
     8821 ctccacccag accgacgata ccggaagcgg cgatcttatc cacgatttcc ttggaagaca
     8881 gcgcacactc cttcactaag gtctcgctgc ggtcgatcgt ctcttcccat tcatcacctt
     8941 ccacatctat atagatagcg ggacgtttgt atccgctagc gtcgagagcg ttatctatct
     9001 tgttcacttt gccggatacg gaagagtgga tgttcgctga tacgaaacca cccgccttgg
     9061 ctagcaatgt acccaccttt accagatccc ctttcttcac cacggcctgc gccggggcgc
     9121 cgatatgctg gctgaggggg ataatcacct gtttaggcgt agcgagagcc gtaattttct
     9181 taccggcaga cagtttattc tcggggggat gtatacctcc gattcgaaat gtccttagca
     9241 tactattaga ttttaattta gatttgtttt ttcttcactt gtagctttcg gagcggcttc
     9301 cggtttcacg gtagcctctg ccttcggcgc cggtttcacg gtctccgctt tcggagcggg
     9361 agcggcttcc ttgcgaggag ggaaattcag ctcatgaata gctcctgtcg gacatacagc
     9421 cacgcatttg cggcacatcc ggcacttcgt ataatcgata taagctacgt tgtttgttac
     9481 ggtgatcgcc tcgaacggac attccttggc gcatttgcca cagccgatac aagcgttggc
     9541 gcaagccttg cgggcggcgg ctcccttatc tttatttacg caagatacgt aaatccggcg
     9601 tgatttaggt cctttctttc tcaactcgat gatactcttc gggcaagcct tcacgcaagc
     9661 gccgcaggaa gtgcattttt cctcgtccac ctcggcgatt cccgtagccg ggttgatgtg
     9721 gatcgcgtcg aaagcgcagg cgttcacgca gtcgccataa cctaggcaac cgaaagaaca
     9781 attcgtctcg cctccgtaaa gggtagaggc gatggcgcaa cttttcgttc catcataaga
     9841 gtttgtacgt gggcgggcct gacaagttcc gttgcaacgg acaacggcta ccatgggttc
     9901 ggttgtaccc gcctctttac ccagtatcgt agcgaccttg gccataaccg ggccaccacc
     9961 aacggggcag agcaatccgt ctaatgagtc agcttttacg caagcgcccg cgaatccggc
    10021 gcaacccgga taaccgcaac ctccacagtt cgccccggga aggacttcct gtacttgcgc
    10081 gatgcgagga tcttcgtaga cttcaaattt cttggaagca gcgtagagga aaaccgctcc
    10141 gaccgccccg attgctccta atgaaataac ggcaattaaa atcatgatat attatcaatt
    10201 aagttttttc aaagtaaata taaatcgtct ttttagtttg tcacgcatta agtatagtat
    10261 acagtaataa ggcagtaaaa gcgataaacc ggttaacccg cttgtggtct cgtcccattg
    10321 tagattcgta ccgatcacga tggcccctac gactatcacc aaaggaatga caaatgccag
    10381 caatacggcc tgaagcccca tggaattttg tccgcatatt atcacttcct cgttaatgcg
    10441 aaaccgtccc gaccgatcgg gtacctcaat gatcttatcc tttttctcgg atgccgagca
    10501 catagactgt gcgtggcatc ccgagcatgc ggattgttgg gtaatgcgga cgaagacggt
    10561 gtcgccatcg atcttctcta caaatcctgt atgatttata ctttcgctca tatttgtaat
    10621 ctcgacattg caaaatcaag gcaaaagtaa gtataattta gaaactatgt cacgattaac
    10681 aaagtttatt attcgaaatc ttaaatccta gcttaccatt tgtaattaaa accgaaactt
    10741 aacaactcat taagctggaa ataactcttg ttatcctctg ttttttccac tccatcgtcg
    10801 tatctaaggt gaaaatagat acgtgtggag aaaaagcggc tgatggccag aaccaaggta
    10861 ttctcgaact ccccgatggt atgatcgcca taagtggtaa agaaataaag acgggattgc
    10921 cagcttacgt tacggttgaa atcgaaggcg aggtctgcgc ggatcgtgga acctatttgg
    10981 cttagcttgt tattgaactc accggtttcc tcgtttttct tgaaaccgtg acggctataa
    11041 tcgatctctt gtgtcgtata catatatgta taggagatcg gcgccaagtt ggtgctgaat
    11101 ttaatcttct tatgcttgtc ggtaaattgt ttttccagct cgtatttcat accgagaccg
    11161 aagttgatag agaacggggc taggaacgcg gcctgtttga tgtgctcgtt ctcttgatag
    11221 ttggtgaaga actgggtctt gaactcagcg tcgaacgtat agtaccattt gttgaacgct
    11281 tggtagccga cgttgctgtg tatacggaag acgtcgtcac cgatcttata gttccttaag
    11341 gtatccttcg gtgctgtata tacgctggct ttgaattcca gttcgttcgt tacttgtacc
    11401 ttatctttct tatagtcgta ttttaaattg ttcttggtga acaggttcaa gttgctactt
    11461 ccacctttat accagttctc cgaaacgtag ttctgggaga attggatggc gctctcgaag
    11521 gccgatatcc agtatctccg ctccgggata aagcgggcgg gagcgtctac gtcctcaaaa
    11581 ttggcatcag cctccacctt gatcggcaag tcctcataaa tattcttctt gatgaattta
    11641 ggtttgatta cctcattggg cagatccctc tcggagtagc ggaaataagt cgggtaattg
    11701 ttctgtacat atttgtaagc catctcctcg aattgtttgt ttcgttccag atctttgaaa
    11761 atggaatctg cccggtatag gttatcatag ggagtcctct ccttcaacga atcgaagttg
    11821 tagaatatca agttctcggg taaataatct ccccggaaaa cgatcggcat gaacaaaggg
    11881 tttacgatca cggtatcccg gaaggtcatc gtattatcga aaatcgtgga ggcgtctcgt
    11941 accagacggg cccaatacat cgcctcgtcc gagatttcca gctcgtcttt cttcaagaaa
    12001 cgcagtaaat tcgtgcttgg ggccaagggc gccgagtaag tcttgttttg cttctcgaat
    12061 tgcttacgaa tgtctacgat gttgtctaat tcctcttcgc taagattgat cgcgggaatc
    12121 gtatcatccg atacgacttg ctgtgcggga cgttgaacta tcgttccggt aactagctgg
    12181 ttctcttggc tgtatgccga gcctccaatt agtgaaagta ataatagcgc atacacacca
    12241 tgcctcttca tcatcataat accttattta catctattag ttgtagtggt cgcaaaatta
    12301 gctaaaaaga atgatatata acatacgatt tgatatttat ctgggcaaaa gttacgatca
    12361 ctgaggcaaa gcaggtgtgt ctaacgaggc ttatacggac ttgcctcagt actccgctgg
    12421 aagtactgga atacttcgct caaagtactt cagtacttcc tgcgtagtac cgaagtaatt
    12481 ccatgagaag tactgtcttt agtgccgggc ttcgggtcgg gaatcggaag agtcctgccg
    12541 aagcccgggt cagttctgga gatattcagc gagaaataaa aacattaaat ttggcatgtc
    12601 tcgatgaaaa tcgctaactt tgcggtttcg aaatgcaggt gtgcaattaa aaagataact
    12661 aaaatattac tatcgtggca gatacaaagt acattttcgt tacaggcggc gtggtctctt
    12721 ccttaggtaa gggtattatt tccgcttctt taggtaagct ccttcaagca agaggttaca
    12781 aggttactat ccaaaaattt gatccttaca tcaacatcga cccgggtacg ttgaaccctt
    12841 atgaacatgg ggaatgttac gtgaccgtcg atggacatga ggctgacttg gacttgggcc
    12901 attacgagcg tttcttgaat gtccagacta cccgtgcgaa taatatcact accggacgta
    12961 tctatcaaag cgtgatcaac aaggagcgta agggggatta tctgggtaag acggtgcagg
    13021 tggtgcctca tatcacggat gagatcaagc gtaacgtgaa attattgggt agcaagtata
    13081 aatttgactt cgtgatcacc gagatcggtg gtacggtggg tgatatcgag tctctgcctt
    13141 tcatagagag cgttcgccag ttgaaatggg agctgggtaa gaactgcctt tgcgtacatc
    13201 ttacttatgt gccttatatc gcggcggcga aagagtataa gacgaagcct acgcaacatt
    13261 ccgtgaagca attgcaggag ttaggcatcc agccagacgt gttggtttta cgtacggagc
    13321 atgagctgaa tgcgaacttg ttacgtaagg tggcgttgtt ctgtaacgtg gccgaggatt
    13381 ccgtgatcca gtcgatcgac gtaccgacga tctacgaggt tcctttggta ttgcaacgcc
    13441 agaagatgga cgaggtggtc ttgcgtaagg tcggtatgga agtcggcccg actccggagt
    13501 tgaagccttg gaaggaattc cttgccttga agagcacggc tacggatacg gtgaagatcg
    13561 gtttggttgg taaatacgtg gaattgcaag acgcttataa gtcgatcgac gagtctttgt
    13621 tgcaagccgc tatttacaat catcataaac tggat
//
