LOCUS       c00396_gnlPro..         4727 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JELDGKEC_396.
ACCESSION   c00396_gnlPro..
VERSION     c00396_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:00:56
            Original ID  :: gnl|Prokka|JELDGKEC_396
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4727
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4727
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[926:4725]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      927..4725
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4727
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4727
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             324..557
                     /locus_tag="ctg396_1"
                     /transl_table=11
                     /translation="MTKLSNIPAKETTAKTARTRKAKTEPAKPKWDPTKPVQFTQEEIW
                     EHIHEIEKGPFYPIEEVHQRIRSWMDNYQGKK"
     CDS             527..883
                     /locus_tag="ctg396_2"
                     /transl_table=11
                     /translation="MDGQLSRKKVIGSPIYEESLERIFVEGIERFGIFQARKYIEYSRE
                     TGKRLSLLSRMPTPSYEKPHVPEHHPRFTPYHLPHHRGTDRGAGHLPFRIQHAKDQENK
                     EYPHRITQRKASHP"
     CDS             complement(927..1970)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg396_3"
                     /sec_met_domain="IlvN (E-value: 7.5e-48, bitscore: 150.9,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.3e-40, bitscore: 127.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYEKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFLEGR
                     GLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(2020..2745)
                     /locus_tag="ctg396_4"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESDPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             complement(2752..3306)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg396_5"
                     /sec_met_domain="ALS_ss_C (E-value: 7.3e-18, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLQEKQQ"
     CDS             complement(3322..4725)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg396_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.3e-51, bitscore:
                     160.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIAGQVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAV
                     SRAFYIASTGRPGPVVLDLAKDAQVGLVDYEYKKVDYVRSYQPEPDIKKDRIKAAADLI
                     NEAKKPFCLVGQGVLLGGAEEELKAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHG
                     NVGPNRKTNECDVLIAIGMRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVL
                     GNAKHTIPMITALLEERKRPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVS
                     EATGNDAVLVTDVGQNQMMGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRT
                     VCFFTGDGGMQMTIQELGTIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMEN
                     PDFVAIAKAYGIASRAVEKREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSV
                     TNMIMGDEK"
ORIGIN
        1 atatgatttt catatactct tttaatgtat aagacgcagt aaatataaga aataaaaaaa
       61 tatgtaataa agacctacac accccaccct cccaaattca tgcttattgt gcgtatatag
      121 cggataagcg attaaaaata gcggttatgt gacataaata aattcgaata ccattttgag
      181 gggatggaga cggggcacgc cccgtctcta caactgggta atgagttaat cctatagacc
      241 tacttttttc cttatcaaat atcttattac atggaaatta ttccatacat ttgccactgt
      301 actaataaat aacagttaca actatgacaa aattaagcaa catccccgcc aaggaaacca
      361 cggccaagac cgcaagaaca cgtaaggcca agaccgaacc cgcaaagccc aagtgggatc
      421 ccaccaagcc ggtacaattc acacaagagg aaatctggga acatatccat gagatcgaga
      481 aggggccgtt ctatcctatt gaagaagtac atcaaagaat aagatcatgg atggacaact
      541 atcaaggaaa aaagtaatcg gttctcccat ttacgaggaa agccttgaga ggattttcgt
      601 ggaaggtata gaacgattcg gcatattcca agcccggaaa tatattgaat acagtcgaga
      661 aactggaaaa cgactatcct tattatcccg aatgccgaca cctagctacg aaaagccgca
      721 tgtaccggaa catcatccta gattcactcc ttatcatcta ccgcatcacc gaggaacgga
      781 tcgaggtgct ggacatcttc cattccgcat ccagcatgcg aaagatcaag aaaacaaaga
      841 atatccacat cgaataacac aaagaaaggc gagccacccg taagtgaccc gcctcttttt
      901 gctgatatat aaggattaag attggattag ttgttctccg gacgaagctt gcgtacagta
      961 acagctgtct gccacatctc gctctcgcgc aatgccttca attcagcctc caatttctca
     1021 cgataatccg gcttagagtt tgagtcgata gagatctgag cctcgttacc gcattttacg
     1081 ttcgcataca atttctcgac aaccggcttg attgcgtcgt ggaacggacc catccagtcc
     1141 aaagcgccac gctgggcagt cgtagagcag ttagcgtaca tccagtccat accattcttg
     1201 gcgaataaag gcatcaagga ttgagtcaac tcctcgaccg tctcgttgaa agcctcagaa
     1261 ggagtgtgtc cattctcgcg caatacctca tactgggcca acaacaaacc ttggatagcg
     1321 cccatcaaag aaccacgctc accagtcaaa tcggaagtag cctcacggat gaaagtcgtc
     1381 tcgaacaagt agccggaacc gataccgata cccaacgcca acgtacgatc catcgccttg
     1441 ccagtagcgt cttgatagat agcgaaagaa gagttcaagc cacgaccctc aaggaacatg
     1501 gaacgcaaag acgtaccaga tcccttcgga gcgaccatga tcacgtcaat atccgcggga
     1561 ggaacaacgc ccgtacgatc gttccaagtg atcgcgaaac catgagagaa atacagggcc
     1621 ttgccagctg tcaaataagg cttcatcgta ggccatacag acattacggc agcgtcggac
     1681 aataagcaca tgatgatcgt ggccttgtcg caagcctcct cgataccgaa cagagtctca
     1741 cccggaaccc atccgtcctc aaccgctttc tcgtaagtct taccttggcg ctggccaacg
     1801 attacgttga agccattgtc acgaaggttc aatgactgtc ccggtccctg tacgccatag
     1861 ccgatcacag cgattgtctc atcttttaat atctctcttg ccttttccaa cggaaattcc
     1921 tcgcgggtca ttacattctc tacaacaccg ccaaaattca tttgtgccat tttcttttta
     1981 actattaatg tttaaaaatc tatttatgta tctcttttat tatctccaag taaccgccgc
     2041 acgacagatc gcctttccct catggcaaat agccatgtct tgcttatcgg gatcggactc
     2101 cgccttatga agcgtaagcg gcataccttg tttgccctcg gattggtagg cgatctccag
     2161 acggccgatc tcacgggtct tgaactggtc gatatcgaac aaatccagca ggtgctcgat
     2221 atacttcacg ctattgaagt gaccgttgat atccaagtcg ctgtatttga tcgaatacgg
     2281 gattccctcc gccttattct ccgccggcat gatcttgccc ggcttctcga tcgggcacgg
     2341 acgctcgtcg atatatttgc ccaatgcctc tatatccaat aaggtaggac ggcgggtctc
     2401 cacgtcgata gccgcccaaa tagaacgggc gaatccaaag gttttcccat tctcatccgc
     2461 cagctcaaaa caacgactgg tgaagaggcg tccgacctca tcgatccaag tgtataaatt
     2521 aatcttatca aaggcggtag gatattcctt catctcgata gccagacggg acaacaccca
     2581 agccgtatga cgctccgaca tatcattgaa accgaaccca cgctctccgg catggctgga
     2641 agcggcgtga atcaaatagt taccaatcat agggagcgtt acacgtcccc taaaatccat
     2701 caaatatggc tccgccacga aatgaaataa tcctactttc tccatatctt attattgttg
     2761 cttttcctgt aactttcgct ccatatcggc caacatatcg ctcaagcgct ccaccttgct
     2821 cttcgtgata gccacacgtc cggagcggat gaattgcagg acaccgatcg tctcactcaa
     2881 ctcattgaac aaggcttgtg tctcgtcata gtggccactc ttctccaata ccacgcaggt
     2941 ctcgttcatc tccaagatac gggcgttgta tttacggatc aatccctcca cggttcccat
     3001 cttgatgaaa agctcggtac ttagcttata aagagcgatc tcttgataaa ccagatcctc
     3061 atccgtatta taataagcct tcaagatatc cacacgttta tcaatctgtt tcaccacctt
     3121 atcgatcata tcctcatcgg cgaatgtcgt gatcgtaaac ttatggatgc ccttgatagc
     3181 ggacggagag acggacagag tctcgatgtt cagctgtcgg cgtgtaaaga taatcgttat
     3241 ctggttcaaa agacctacga tattctctga aaagataata acggtatata atttctttgt
     3301 tctcatagct tcatctcctc cttatttctc gtctcccata atcatgtttg tcacgcttcc
     3361 cccagcagga accatcggat ataccattcc gcaagtctcc acgttagcaa ccaacacgta
     3421 agcgccgtcg tggtttagca tctcggcgat agcgtcgtcc aattcctccc gcttttcaac
     3481 ggcacggctg gcgataccat aggctttagc gatcgccacg aaatccggat tctccatgat
     3541 ggtgtttgaa taacgctcgt ggaagaacaa ttcttgccac tgacgtacca tacctaagaa
     3601 gttattatta agaataataa tcttcacgtt cagtttctcc tgcatgatgg tacccaattc
     3661 ctgaatcgtc atctgcatac ccccatcacc ggtaaagaag cagaccgtac ggtctggagc
     3721 cccgaactta gcgcccatag cggccggcag accaaatccc atcgtaccta aaccaccgga
     3781 agtcaccacg ctacgggttt gtttatattt gaaatagcgg acacccatca tctggttctg
     3841 cccaacgtcg gtcaccaata cagcgtcgtt accggtcgcc tcggaaacct tacggactac
     3901 ctcgcccatt ttcagttggc cctcggtcgg atacaattcc ttctcgatta ccttatcgta
     3961 ttcctctttc tcgtcccgat cgaactcggc attccattcc ggacgtttac gttcttccaa
     4021 caacgccgtg atcatcggta tcgtgtgctt ggcattcccc agcaccttta catctacggg
     4081 gacgttctta ccgatttccg agttgtcgat atccagatgg ataatcttgg cttgcttagc
     4141 gtatgtcttt aaatcgccag tcacacggtc gtcgaaacgc ataccgatag cgatcaatac
     4201 atcacactca ttcgttttcc ggttcggccc tacgtttcca tgcataccga gcattccctt
     4261 gttcaatggg aaatcggttg gcaacgcaga taagcccaat accgtagatc cggcaggtat
     4321 atcattcttt tggagaaacg ctttcaattc ctcttccgca ccgcctaaca atactccctg
     4381 cccgaccaga cagaagggtt tcttcgcctc attgattaaa tcggcggcgg ccttgatacg
     4441 atcctttttg atatccggct ccggctgata actacgtacg taatctacct tcttatattc
     4501 atagtccacc agccctactt gcgcgtcctt cgctaaatcc agcacaactg gacccggacg
     4561 gcctgtagaa gcgatataaa aagcacgaga aacagcccat gcgatctcct ccggcttgcg
     4621 gatttgataa gcccatttcg tgatcggttg cgtgatgcca atcacgtcga cttcctgaaa
     4681 agcatcggtt cccaacaacg gcgagggtac ttgaccggcg attacga
//
