LOCUS       c00158_gnlPro..        13429 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMEMPLHF_290.
ACCESSION   c00158_gnlPro..
VERSION     c00158_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 11:01:57
            Original ID  :: gnl|Prokka|BMEMPLHF_290
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13429
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13429
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5786:9003]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5787..9003
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..13429
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13429
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(284..1213)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg158_1"
                     /sec_met_domain="PLDc_2 (E-value: 5.5e-27, bitscore: 84.4,
                     seeds: 83, tool: rule-based-clusters)"
                     /sec_met_domain="PLDc (E-value: 1e-08, bitscore: 25.3,
                     seeds: 30, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDTSGSRGTKPSFFDHLRELGGEAQPFISTSKKHWFTTPRLNYH
                     LHRKLVIIDHHIGYIGGFNIGDQYVNKSPKFGHWRDTHLRVIGQSPILMEVRFAMDWNT
                     SIRRTNLPKFELKELKPFTVNRKDINDNKNVAMQIVSSGPDNQHYGIRRGYEGIIAGAK
                     KYIYIQTPYLIPEESILEALIIAANSGIDVRIMVRCMPDHPFVYRATEYYAKYLVALGV
                     KVYKYNDGFIHAKTMVSGSNIFSVGSANQDFRSYTLNFEVNSFNYNPALTQELKKIFEK
                     DLDKCTLLINDLNFPLTKVGLYLENSII"
     CDS             complement(1281..1706)
                     /locus_tag="ctg158_2"
                     /transl_table=11
                     /translation="MDYQYVWTVFRSRRSVVATWAWMLVLTVLPSIGFILYLFFGRQLS
                     HDEIFAIQEEQKKVQRHYLAEQRDMLKEHDLLPEKERLPRVRMLSELNLNNDDAILTFD
                     NQVKVFISGPELFDQMITDIKNAKKSVSLEFYTFYSD"
     CDS             1902..2402
                     /locus_tag="ctg158_3"
                     /transl_table=11
                     /translation="MLRKQIISAAGIMLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTR
                     NATVYNRHGVKVGHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVV
                     NRIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINKKPFIKIADGEYVKALNVLTTV
                     TNH"
     CDS             complement(2470..4752)
                     /locus_tag="ctg158_4"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGEFKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSDLSDLPDKDVLALAGSATDKRNAGII
                     DIAIDEYLKENNIPAMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EAVEGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSRAALAELKKRGVRPIMLTGDNQR
                     TAAAVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTG
                     DGVNDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWS
                     LTKLARTAELTMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENW
                     NMARLAKIAFSLAAGWTVIGIAFVSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTR
                     KYFWQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIY
                     QPVMKNR"
     CDS             4881..5735
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     76.4; E-value: 4e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg158_5"
                     /sec_met_domain="LysR_substrate (E-value: 4e-30, bitscore:
                     94.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1e-24, bitscore: 76.4,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAEEKQITSAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGINAKTLTTE
                     RMMAVTVDPKFKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKHSNWITHLQLVWRKDQKVTPLMKRIIDS
                     LSR"
     CDS             5787..7016
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_6"
                     /sec_met_domain="Amidinotransf (E-value: 3.1e-106,
                     bitscore: 345.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEKQGVHVVYLEDLLAQSLTNEDVRTKFVDQLLEESNIKKEDSLHQ
                     LLMDYLIAMPVNEMVKQIIAGIRKNEIQNVTPSLADLAEDPDYPFYLNPMPNVYFTRDQ
                     QAAIGNGMTINGMTFRARRRESLFMETVLKHHPDFKNANIPIWRDRYTHGRLEGGDELI
                     LNNHVLAIGISQRTSAAAITDLAHSLFGHSSYDTILAIKIPHNHAMMHLDTVFTMINYD
                     QFTVHPFILDKSGKIDIYVLEQDDHGEIKITPETNLIKVLKNYLHLSEIDLIPTGGGDA
                     IAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGILVHEIHSSELSRGRGGPRC
                     MSCPLVREDL"
     CDS             7028..8068
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_7"
                     /sec_met_domain="OTCace (E-value: 1.3e-51, bitscore: 164.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 1.4e-48, bitscore:
                     154.8, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSLLKCKDYTPAELNYLIDFALHLKELKKENIPHE
                     YLKGKNIALLFEKSSTRTRSAFVVACNDLGANPEYMGAGEIHLGKKESIEDTAKVLGSM
                     FDGIEYRGFAQKDVEDLAKYSGVPVWNGLTDKWHPTQMLADFMTIKEKFGHLKGLTLAY
                     VGDGRDNVADSLLVAGSMLGVNVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIE
                     QGVKGANIIYTDVWVSMGENDWSERIKLLKPYTVTMKMMHMTGTSDDQLIFMHCLPAFH
                     DRTTKVGEEIYKKYGLSEMEVTDEVFNSQYAWQFTEAENRLHSIKAIMAATLGNLFIPS
                     VDEGSK"
     CDS             8071..9003
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_8"
                     /sec_met_domain="AA_kinase (E-value: 2.7e-36, bitscore:
                     115.4, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVALGGNAIEAGDNSAAAQEKQVEKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNPAMPLDTVVAMTQGSIGYWMQKALDDQFKHTNYSH
                     QAVALITQTIVNANDPTFKNPTKPIGPFYTFNEMQKQKIYHPEYTYKQDAGRGYRQVVS
                     SPKPVKIINAPVIDTLLKSKFVPIAAGGGGIPVVVKDDSLQGVAGVIDKDFSAVKLAED
                     IQADELVILTTVDNAYVNYNQPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDF
                     VEKTGKTAIITSLRNASKLDDGVGTIVYN"
     CDS             9020..9556
                     /locus_tag="ctg158_9"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNKGYDYKLLKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKPALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             9677..10843
                     /locus_tag="ctg158_10"
                     /transl_table=11
                     /translation="MKLKKNQDDLKQIASLIEYAFLKDSDLTTDSNFMTRYDHSAGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQK
                     ILVANLAPFSENFYRHYGFSNSIYQKEYGFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHTDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMVAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKILSCMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFIKGKVSFYDYF"
     CDS             10859..11020
                     /locus_tag="ctg158_11"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLSVVVSGINVVISLLIMLNKYQIRKDKKQIADE
                     GHAPLDEN"
     CDS             11023..11628
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg158_12"
                     /sec_met_domain="LysR_substrate (E-value: 5.1e-18,
                     bitscore: 55.2, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKNSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEDAVIKDFILLVKKVY"
     CDS             11705..11827
                     /locus_tag="ctg158_13"
                     /transl_table=11
                     /translation="MLERKLLPLSAMVLALGLSGLTTHVKAADTPLMVMVTERL"
     CDS             11824..12249
                     /locus_tag="ctg158_14"
                     /transl_table=11
                     /translation="VTVHKKMQGTWYSYDSNAHSGRKITFTAHTVNGKINYTQDKSIIS
                     DYFNGNIQDQAGFDRATKNWMSGQTTKMKNNLFYEINPWISFENWSLYRVMPQKINGKK
                     HNVLLYSSRYDGGNYYRSKKLAKQMKNYKFKKVDYHL"
     CDS             12462..13025
                     /locus_tag="ctg158_15"
                     /transl_table=11
                     /translation="MLNAKNALFMQSGHEDQRKYKNYLIESYQNDDAYQKHESLSQVQQ
                     FERDLKDIVNSQVKVKLYPEFISTKPEKLAITHDNQYVVYLTEIGVQLGKGDEFANAVM
                     KEMKTAVEKEDGILAMIAGTIMNQPNEWFSLEVYKTEETYEEYHKTKHFKKYLEATKYV
                     VESKGLHLLKPDCIMDQGEIFYRP"
     CDS             13304..13429
                     /locus_tag="ctg158_16"
                     /transl_table=11
                     /translation="MNDFTKNMAQALFNQDKVNDFLRKEIQTAVNQLLEAELTAFL"
ORIGIN
        1 tacatgcttc tgtctcgaaa cacattactg aagatgtatg aaaggatcga ccaaagtggg
       61 attcctttgg acttgcggag cccacatcta cggagaagct ccataacttt gtagtccttg
      121 aagaactttt caacagaacg ggcaatttta ggttcgtttt cagtatcgaa tgatggtaaa
      181 ctagacatag cgcaagcctt tcgtttgatt tcgtttgata ttgatgatgt tttgatcgac
      241 ttaattatat caagcgaaca aaggccttgt gcttttttat tggctaaatt attgaatttt
      301 caaggtacaa gcccactttt gtaagtggga agtttaagtc attaattaaa agggtacatt
      361 tatctaagtc cttctcaaaa attttcttta attcttgagt taaagcaggg ttgtagttga
      421 atgagtttac ctcaaagttt aatgtatagc ttcggaaatc ttgattggcg gaaccaactg
      481 aaaaaatatt agaaccgcta accatagttt ttgcatgaat aaaaccatca ttatatttgt
      541 atactttaac gccaagggct actaaatact tagcatagta ttctgtagca cgataaacaa
      601 atggatgatc gggcatgcaa cgaaccataa ttcgaacatc aataccgctg ttagcagcga
      661 taattaaggc ttcaagaatt gattcttcgg gaattaaata aggcgtttga atataaatgt
      721 attttttagc tcctgcaata attccctcat agcctcgtct gatgccgtaa tgttgattat
      781 caggtcctga ggaaacaatt tgcatagcga catttttatt atcattgata tcttttcgat
      841 tgacagtaaa tggtttaagt tcctttaatt caaatttagg taaatttgtt cttctgattg
      901 acgtgttcca gtccattgca aaccggacct ccattagaat tggtgattgc ccaattacac
      961 gtaaatgggt atcccgccaa tgaccgaatt ttggtgattt attgacatat tgatctccaa
     1021 tattaaatcc gccaatatag ccaatatggt ggtcaataat aactaatttt ctatgtaagt
     1081 ggtaattgag tcgtggggta gtaaaccagt gcttttttga agtggaaata aatggttgag
     1141 cttcgccgcc caattctctt aaatggtcaa aaaagcttgg cttagtgcct cttgatccag
     1201 aggtatcata cataaattac tcttacctta gcaccattag ctgcagcctc ttccaaggct
     1261 tttaaagcac gatgccctaa ttagtcagaa taaaaagtat aaaattctaa gctgacagat
     1321 tttttggcat ttttgatatc agtaatcatt tggtcaaaaa gttctggtcc agaaataaat
     1381 actttgacct gattatcgaa agttaaaatc gcatcatcgt tgttaagatt tagttccgac
     1441 agcattctta ctcgtggaag acgctctttt tcaggtagaa gatcgtgctc tttaagcatg
     1501 tcgcgttgct cagctaaata atgtctttgt accttttttt gctcttcttg aatagcaaag
     1561 atttcatcat gtgaaagctg acgaccaaag aaaagatata ggataaaacc gatactgggc
     1621 agaacggtta atacaagcat ccatgcccaa gttgcaacaa cgctgcggcg acttctaaag
     1681 accgtccata catattgata atccataaga cttcgatagt cctacggatt atatcccaag
     1741 ttaaaatcat gaataattac tcccttgtaa gtagtgttat aaataatttt agcagaatta
     1801 agcaaatagt tataaaacag atgagtaaaa aatgcttcca attcgataat ttttgataaa
     1861 ataagggatg gagaatggta taaacactac gggggtggat tatgttgaga aaacaaatta
     1921 tttctgctgc aggtataatg ttagcagtta ttggattagg cgcagcaact acacaaagcg
     1981 ttgatgcagt tgttactaat ccagttagac aaggtaagag attaaatcta actagaaatg
     2041 ctactgttta taatagacat ggtgttaaag ttggacattt aagaaaggga aagctttaca
     2101 aagtacgtgc cataaaagta attaatggta atacttatgt aaagattcgt aaaaatagat
     2161 ttgttaagga agaagccttc ttgccatata tgaagactac tgtaaaagta gttaatagaa
     2221 tcaaaaagca ttcctttgtt tatgatgaga atggtgaaaa aatcccaggc aaatttttaa
     2281 agcgtggtgc taaggttaac tatttaggcc ataaagaaat taataaaaaa ccatttatca
     2341 aaattgctga tggtgaatat gttaaggctt tgaatgtctt gactacagtt actaatcatt
     2401 aatcaaaaaa acactctgaa aactacatta ctacaatgta gttttcagag tgtttttgtt
     2461 ttaagttaat tatctgtttt tcattactgg ttgataaatc aaatcaataa taattgctgc
     2521 aattaatgca accacaacgg taattaataa gttttgccaa ctaatttgag ccattgctaa
     2581 accgcataaa gctaaaataa aggttaatgc gacatcggca atttgaacaa tacctacaag
     2641 tttagatggg taatcttgcc agaagtattt acgagttcta gtaattaata caattaacat
     2701 tgcacttaga actaagtaaa catagaccat ggtagagata gaattgtgac tccagccatg
     2761 catgttgagg tagctgacaa aagcgatacc gataactgtc caacctgcag caagagagaa
     2821 tgcgattttg gctaaccttg ccatattcca attttctggt ttgtaagtaa tatgggtacg
     2881 gtccgtacca atcatcatgg taaccatgtt attcatgatt gtgtaaataa ccatagcatt
     2941 taatgccatt ggaatatagt tgaagaagag atagccgaag gttaaaagca tagttaattc
     3001 ggcggttctg gcgagcttag taagtgacca agtagtcatt cgttgatata cacggtgacc
     3061 agcatcaaga attttaacaa tagagcttaa gccatcatct agaagcacca tcttacttga
     3121 acgcttggca acatcggcag cgttagaaac agcaatacca acttcagctt gctttaaagc
     3181 aggagagtcg ttaacaccat caccagtcat accaacgata taaccttttt cttggaagaa
     3241 tttaaccatc ttaagtttat cttcaggtaa aacatcggca atccctgcta attcatcaat
     3301 atcggtgctt tcatcaaagt catgaataga gataacgtta ccagttaaat caacttgttc
     3361 agcgactgct gcggcagttc tttgattatc accagttaac atgattggac gtacgccccg
     3421 ttttttaagt tctgctaaag cagccctaga gtcctttctt actttatctt gtaaaataaa
     3481 tactcccgca agtttgtcat caattaacac ggcaactgag cgtccagctt taaaattgat
     3541 gccttcaact gcttcaactg cttcatttgc attcttatcg attaatgaaa gttgcttaaa
     3601 tgaacctaac ttaacattgt gaccatctac ttcagccata gaatagccag tgtcagaagt
     3661 aaatggggta aagtgttcaa cgtccatggc agggatatta ttttctttta agtattcatc
     3721 aatggcgata tcaatgatac ctgcattgcg cttatcagtt gcactaccgg ctaaagcaag
     3781 tacatcttta tctggcaaat cgcttaaatc gctccaacta gcaactgcag ttttgttttc
     3841 agtgattgtt cccgtcttat caagtaaaag caagtttaag ttagctgcat cttggatacc
     3901 agttaaatca gctgttaaga cgccttcttt acttaaacgg gttgcttcaa atgaattgga
     3961 caatgcaaag gttgacggca tcgcaaccgg aattgaagcg atgaacatca tggctaagaa
     4021 tggcaacatg ttgataaacg tatcaaaatt accaccctta aagaatgaag caatgataat
     4081 aactaaggta agtacaccgt caagtaggca aaggtagtaa ataatcttag ttaaaagttg
     4141 ttgcaagtga ccaggtgcag ctgaattgtt gatcaagtta atggtcttac cacttcttga
     4201 atctttacca gttgcagtaa caattgctaa tccatcgcct tcaacaacag tagtaccagc
     4261 ataagctgtg tcatcaatgt tctttttaac gggcttgaat tcaccggtaa ttgagctttc
     4321 atcacaggcg atcttaccgc taaccatttt tacatcggct gcaagtacat ctccacgttg
     4381 aagtgagatt aagtcgcctc taactaattg cttagagtca attttgatcc acttaccatc
     4441 gcgttctaca gccaccttag gggttagctt atgtgaaatg gtatttaata cccgccgtga
     4501 ctgtttcttc ttggatgcac cgttaaaagc cgcaaaaaga agcatcaaca agacgaacaa
     4561 agattgaatc catttgccta agatacattc gaggattaag gcaccttcta gaatccaggc
     4621 agaaagattc cataattttg atagaaattc cttaaaaaag ttgtattcgg gttcaggtac
     4681 ttcgtttaac ccatcttctt taagtctctt atctgcttcg gcttgagtta agccatgaaa
     4741 tttttcagac attttattcc ctccaaatct accttaataa agtagcacat atgttgtttg
     4801 aatgaaaata ctaaattaaa atataagata tagaaatttt taataagaga tacaactaaa
     4861 ataaaaagga tagattatta atgaatatta aacaattacg ctacttttta gtagtagccg
     4921 aagaaaagca aatcacttca gcagctaaaa gactatacat tgcacaaccg ccgctgagtt
     4981 atcaattaaa gcaactagaa aaagaactag gagcacaatt atttaagcgt actgctcatg
     5041 gaattgaatt aacagatgct ggacaaattt tgcagagcta tgctagtgaa attctctctt
     5101 tatcagaaag cgtgaaaaat caggttcata aaactgtttc aggtgaacta ggcacgattg
     5161 caataggcat ggcttcatca tcaactggac taattcctat gaaaagtttt caagatttaa
     5221 ctaagtttta tccggaaatc aactttgata tttatgaaga taataccttt ggcattatcg
     5281 ataaattgga aaagaagaca atcgatttag gaattgtgcg tacgccttat aatcgtaatg
     5341 gcataaatgc aaaaacttta actactgaaa gaatgatggc agttactgtt gatcccaaat
     5401 ttaaggataa gacggaatta aggattaaag atctaaatga gcagcccctc attatttatc
     5461 gaagatttga agaaattttt aaccagactt ttgctcatca tgggattaag ccgttttatg
     5521 ctgttaaatg tgatgattct agaacagcga ttacttgggc gaagagaaaa atggggattg
     5581 ctcttgttcc tgaatctatt gcttctacgt atgcacctga tgatcttatt cctattaaac
     5641 atagtaattg gattacgcat ttgcaattag tgtggcgcaa ggatcaaaag gtgacgcctt
     5701 taatgaagag aataatagat tcactaagcc gttaagattg taacttctac ctaattgatc
     5761 cataatttga attaagaggc gatataatga ctgacttaat tcatgtttat tccgaaattg
     5821 gcaaattaga aacagttatg ctgcatcgac cgggaagaga attagaaaat ctttcaccgg
     5881 atatcttaaa tcgaatgtta attgacgata ttccatattt aaaaatagct caaaaagagc
     5941 atgactattt tgcccacact ttggaaaaac agggagttca tgtcgtttat ttagaagatt
     6001 tattagctca gtctttgact aatgaagatg tccgtacaaa atttgtagat caattattag
     6061 aagaatccaa tataaaaaaa gaagattcat tacatcaatt actgatggac tatttaatag
     6121 caatgccagt aaatgaaatg gttaagcaaa taattgctgg tattagaaaa aatgaaatac
     6181 aaaatgtaac tccttcatta gccgatctag ctgaagatcc agattatcca ttttatttga
     6241 atccaatgcc aaatgtgtat tttactcgtg atcaacaagc agctattggt aatggcatga
     6301 ctattaatgg aatgacgttt agagctagaa gacgtgagtc attatttatg gaaaccgttt
     6361 taaagcatca tcccgacttt aaaaatgcca atattcctat ttggcgtgat cgttacactc
     6421 atggacgttt agaaggtggc gatgagctga ttttaaacaa tcatgtttta gcaatcggta
     6481 tttctcaaag aacttccgct gccgcaatca ctgaccttgc tcatagcctg tttggtcatt
     6541 ctagttatga cacaatttta gcaattaaaa taccacataa tcatgccatg atgcatctgg
     6601 atacagtctt tacaatgatt aattatgatc agtttaccgt tcatcctttt attttagaca
     6661 aatcaggaaa gattgatatt tatgttttag agcaagatga tcatggtgag attaaaatta
     6721 ccccagaaac taatttgatc aaagtgttaa agaattattt gcacttatcg gagattgacc
     6781 taattccaac cggaggtggg gatgcaattg cagccccaag agagcagtgg aatgatggct
     6841 cgaatacttt ggctattgcg ccaggtgaag tcgttacata tgatcgtaat tatgtatcaa
     6901 atgatttgtt aagaaagcat ggcattttag ttcatgaaat tcattcaagt gagctttctc
     6961 gtggccgtgg aggtccaaga tgtatgtcat gtccacttgt tcgtgaagat ttgtaagagg
     7021 cgtcaaaatg aaatatttac aaaatgtgtt tcaaggcaga agtttattaa aatgcaaaga
     7081 ctatactcca gcggagctta actatctaat tgatttcgca cttcatttga aggaactaaa
     7141 gaaagaaaat attccgcatg aatatttaaa aggaaagaat atagctcttt tatttgaaaa
     7201 atcttcaaca agaacacgtt cagcctttgt agttgcatgc aatgatttag gtgcaaatcc
     7261 tgaatatatg ggtgctggtg aaattcattt aggtaaaaag gaaagtattg aagatactgc
     7321 aaaggttttg ggcagtatgt ttgatggcat tgaatatcgc ggttttgctc aaaaagatgt
     7381 agaagatttg gctaaatatt ctggtgtccc tgtttggaat ggtttaacag ataaatggca
     7441 tccgacccaa atgttggctg actttatgac tattaaagaa aagtttggac atttaaaggg
     7501 acttacttta gcttatgtag gtgatggacg tgataatgtt gccgacagtc ttttagtggc
     7561 tggcagcatg cttggagtta atgtacacat agttacgcca aagcctttat tcactcaccc
     7621 tgatgtacaa aaaattgcag aaggttttgc caaagattct ggatcaagaa atttgattac
     7681 tgatgatatt gaacaaggcg ttaaaggtgc aaatattatt tatactgatg tctgggtatc
     7741 aatgggtgaa aatgactgga gtgagagaat caaattgtta aagccttaca cggttacaat
     7801 gaagatgatg catatgacag gcacctcgga tgatcaacta atctttatgc actgtttgcc
     7861 tgcgtttcat gatcgcacta ctaaagttgg cgaagaaatt tataaaaaat atggtctaag
     7921 tgaaatggaa gttacagatg aagtctttaa ctctcaatac gcttggcaat ttactgaagc
     7981 ggaaaataga ttgcattcta tcaaagcaat aatggccgct actttgggca atttgtttat
     8041 tccgtcagtt gatgaaggaa gtaaataaag atgaaaagaa tagttgtagc tttgggtggc
     8101 aatgctattg aagcaggtga taatagtgca gctgcccaag aaaagcaggt tgaaaagaca
     8161 atgaaggttg ttgctaaaat gattgaaaat ggtgatcagg tagcgattgt tcatggtaat
     8221 ggcccgcagg ttggtaattt gcttttgcaa caatacaaag gttcaagtaa agataatccc
     8281 gctatgccgc ttgatacagt agtagcaatg actcaaggca gtatcggcta ttggatgcaa
     8341 aaggccttag acgatcaatt taaacataca aattattcac atcaagctgt tgctttaatt
     8401 actcagacaa tagttaatgc gaatgatcca acttttaaga atccaactaa accaattggc
     8461 ccattttata catttaacga aatgcagaag caaaaaatct atcatcctga atatacttat
     8521 aagcaagatg caggtcgagg ctatcgtcaa gtagtttctt ctccaaagcc cgttaaaatt
     8581 attaatgcac cagtcattga cactttacta aagagcaagt ttgttcctat tgctgccgga
     8641 ggtggtggaa ttcctgttgt agtgaaagac gatagtttgc aaggcgtagc aggagtaatt
     8701 gataaagact tcagtgccgt aaaactagct gaagatattc aagcagatga attagttatt
     8761 ctaactactg ttgacaatgc ctacgtgaac tataatcaac ctgatcaagc tcctattgga
     8821 aaaataaaga ttgatcaatt aaagaagtat ctagaagctg gccaatttgc cgcaggcagc
     8881 atgaagccaa aaattgaagc tgtcattgat ttcgtagaga aaacaggaaa gactgcaatt
     8941 attacttctt taagaaatgc aagtaaactt gatgatggag taggtacaat cgtttataat
     9001 taactgcggt gagatataaa tgaacatttt tcaagaagga aatccgcaaa atattgctca
     9061 ggtattagct ggaaaagatt atcgtgtagc tttgcagcaa gctattttta aaaagtatcc
     9121 tgatgcgact ttggttgata taaacttaaa tatcccgggg ccaattaaaa ataatcgata
     9181 tttaatcaaa ttatttgatt acggaattaa acaattagaa gaaatatggc agaataaggg
     9241 atatgactat aaattattaa aagcattaaa taatgatgct ggatgtgaaa atttctatgt
     9301 tttgcgagaa tctagcaaag tagttaaatt atctacaatt ttatttgaag aaaataataa
     9361 aataggacga ttatttgatg ccgatgtatt aattaaaggg aaacctgcac tttcacgcca
     9421 agagcttgaa tactctagtc gccgctgcta tttatgcaat cgccctgcta aagagtgtgc
     9481 tcgatcacgg cgacactcag tagaagagat gcaaagatac atttctagtt tatatgcgaa
     9541 gtatgtaaat aattaaaacg ggatgggagg ctaatcatcc cgttttttca tttaaatcta
     9601 aaaaaaagct aacgaaaaat gcataaaatg ttctaaaata taagtaaagt tatgaatata
     9661 tattgtaagg aaaactatga aattaaagaa aaaccaagac gatttaaaac aaattgcttc
     9721 attgattgaa tatgcttttt taaaagattc tgatttgact acagatagta actttatgac
     9781 ccgatatgat catagtgctg gatatggata ttttgatcaa gaaaaattga ccagttatat
     9841 gatggtcaat aagtttaaag ctgagatatt tggtcatcat gttccattgg caggtattgg
     9901 ttatgtggca tcatatcctg aatacagagg acgtggacat atatctaaat taatgaaaga
     9961 aattcttttt gatttgcatg atcaaaaaat cctagttgca aatctagctc cattttcaga
    10021 aaatttttat cgtcattatg gttttagcaa tagtatttac caaaaagaat atggcttttc
    10081 gggggctgca cttgcttctt tcagattacc acgcaaaggt aagataattc gtggaaaatg
    10141 gaatgatttg attgttcaaa atggtgtgat tcaattatat gaacgtcagt tgcatactga
    10201 cgatgaaaga aatacgatca tcagagaagc ttggtggtgg aatagattag atgattatta
    10261 tcatcatcga gagattgctg tttacttcga tgaagctggt cggccgatga gctacttgat
    10321 ttatcgcata attgataact gttttatggc tgatgaatta tattcaatta cgcctcaagg
    10381 attattaagc atattaggct ttatggtagc tcatataggg tcaattaaag agttttgtat
    10441 gacattgcct gagaagtctt tattggctga actttttcca gagcaaaatg aattggatat
    10501 tcaacttcat ccatatatga tgagtagaat tattgatttc caaaaaatct tgtcatgcat
    10561 gcgcccattg caagagggta cttttaacat cgaagttaat tatgatgatc agtgtccatg
    10621 gaatattggc gtttggcaat taactaatta tgatcaccaa gttaagtgtg aacgaaaaga
    10681 agatgaacta gttgatttct ctggtccaat tacaacatgg actcaaatct tattaggacg
    10741 tttaactatg gaatccgcaa ttaaacttgg tttgatcaca gattatcgaa ttaaaaagtt
    10801 ggactttata aaaggtaaag tctcatttta tgattatttt tagaagaagg tatctaaaat
    10861 gagtaagcaa aagaaagtta gattactaaa atttttaagc gtggtagtta gtggaataaa
    10921 tgtggttatt tcgctattga ttatgctcaa caaatatcaa attagaaaag ataaaaaaca
    10981 aatagcagat gaaggtcatg ccccattgga tgaaaattaa ctatgaaaaa attgagaata
    11041 gcatacttta accaacttgg tagaagacaa ttagatcgaa ttgtagacca atttaagcaa
    11101 aaaaattctg atgtagaaat tgaattaatt ggaatgggac acgatgaagc ttttgataaa
    11161 ttagccaaaa atgaagttga tttagcgatt agtgatttgc gcgatgatca gctcgatttt
    11221 aagaaggaaa tcttaggtca ggaagcagta atggctattt tgcaaaaggg tagttatcct
    11281 agcggtgttc agatgatcaa taaagatgat ctagctgatt taacctgttt tattgtagct
    11341 aagcctgaag aagaggctgc agaactccat ttatttaaag atatttatca gattagaagc
    11401 ccattcattg cttcaaattc cgtagaagag gcagcattgt tagtagcttc tggatcagga
    11461 tattttttaa tgaatgaagc aaccgccagt ttaattagta atgatacttt acaacgattg
    11521 tttttattgt ctaatggaca acaaatgtgg caaaagattg cagcttttta taccaatgaa
    11581 gatgcagtaa ttaaagattt tattttgtta gttaaaaaag tatattaatc tatcttggaa
    11641 cagcaaaata ctgtaaaatt aataatgaaa gcgaatccat aattttacaa ctggagatga
    11701 ttttatgcta gagagaaaat tattgccttt gtcagccatg gtactggctt taggcttgag
    11761 cggattaaca acgcatgtaa aggcagctga caccccactt atggtaatgg taacggagcg
    11821 gttgtgactg tgcataagaa gatgcagggg acatggtact catatgatag taatgcacat
    11881 agcggtagaa aaattacttt tactgcgcat acggttaatg gaaaaatcaa ttacactcaa
    11941 gacaaatcaa ttattagcga ttactttaat ggcaatattc aagatcaggc tggctttgat
    12001 cgagctacca aaaattggat gtcaggtcaa acaactaaga tgaaaaataa tctattttat
    12061 gagattaatc catggattag ttttgaaaat tggagtctat atagagtaat gcctcaaaag
    12121 attaatggta aaaagcataa tgttttactg tattcaagta gatacgatgg cggcaattac
    12181 tatagaagca agaaattggc taaacaaatg aaaaattata agtttaaaaa ggtagactat
    12241 catttgtaaa atttaatata gaagaaaagc ttcaaattat agaaattatg ttaagttgat
    12301 tttggcagta acttttttga aaaaatagtt tataatatca ataaaaatta atttggtagg
    12361 aataaaaaat aaaattagag aatgcacctg ttttaaattt atttagatta gaaataaatc
    12421 ctgaaaagca tgaaatatat actaaaaaag tggaaaagta tatgttaaat gcaaagaatg
    12481 cattatttat gcagagcggt catgaagatc aaaggaaata taaaaactac ttgatagaaa
    12541 gttatcaaaa tgacgatgct tatcaaaaac atgagtcttt aagtcaagtc cagcaatttg
    12601 aacgtgatct gaaagatatt gtaaatagtc aagttaaagt aaaattatat cctgaattta
    12661 tttcaactaa gccagaaaag ttagctatta cgcacgataa tcaatatgtg gtttatttaa
    12721 ctgaaattgg tgtgcagttg ggtaagggcg atgaattcgc caatgcagta atgaaagaaa
    12781 tgaaaactgc ggttgaaaaa gaagacggca tcttggcaat gattgctggt actattatga
    12841 atcaaccgaa tgaatggttt tcattagaag tatacaaaac tgaagaaaca tacgaggaat
    12901 atcataagac taaacacttc aaaaaatatc tagaagctac caagtatgtg gtagaaagta
    12961 aaggtcttca cctacttaaa cctgattgta taatggatca aggagaaatt ttctatcgac
    13021 cataagaaaa agcaagttat ttagttgaaa aataacttgc tttttgaatt atttgcaatt
    13081 gtttcgattc tttactttaa cagggagagg cttattaact aacgtagagc tgatagccat
    13141 gattcctgca gttgctaacg caactgtaat ggagaccgta aaatagtttg tgtaaggatg
    13201 aatgattcct taaattaatt tctgaaaaca ttagaaaaag gagttccttt ctcgtatgat
    13261 tggattgaac aaaaaaacaa catacagaaa gaagaactcc ttcatgaatg attttaccaa
    13321 aaatatggct caagcactat tcaatcaaga caaagttaat gattttttgc gcaaggaaat
    13381 tcaaactgca gttaatcaat tgcttgaagc tgaattgact gccttttta
//
