LOCUS       c00142_gnlPro..        13443 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LNBENCLP_241.
ACCESSION   c00142_gnlPro..
VERSION     c00142_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 11:15:25
            Original ID  :: gnl|Prokka|LNBENCLP_241
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13443
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13443
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5779:8996]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5780..8996
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..13443
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13443
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(277..1206)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg142_1"
                     /sec_met_domain="PLDc_2 (E-value: 5.5e-27, bitscore: 84.4,
                     seeds: 83, tool: rule-based-clusters)"
                     /sec_met_domain="PLDc (E-value: 1e-08, bitscore: 25.3,
                     seeds: 30, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDTSGSRGTKPSFFDHLRELGGEAQPFISTSKKHWFTTPRLNYH
                     LHRKLVIIDHHIGYIGGFNIGDQYVNKSPKFGHWRDTHLRVIGQSPILMEVRFAMDWNT
                     SIRRTNLPKFELKELKPFTVNRKDINDNKNVAMQIVSSGPDNQHYGIRRGYEGIIAGAK
                     KYIYIQTPYLIPEESILEALIIAANSGIDVRIMVRCMPDHPFVYRATEYYAKYLVALGV
                     KVYKYNDGFIHAKTMVSGSNIFSVGSANQDFRSYTLNFEVNSFNYNPALTQELKKIFEK
                     DLDKCTLLINDLNFPLTKVGLYLENSII"
     CDS             complement(1274..1699)
                     /locus_tag="ctg142_2"
                     /transl_table=11
                     /translation="MDYQYVWTVFRSRRSVVATWAWMLVLTVLPSIGFILYLFFGRQLS
                     HDEIFAIQEEQKKVQRHYLAEQRDMLKEHDLLPEKERLPRVRMLSELNLNNDDAILTFD
                     NQVKVFISGPELFDQMITDIKNAKKSVSLEFYTFYSD"
     CDS             1895..2395
                     /locus_tag="ctg142_3"
                     /transl_table=11
                     /translation="MLRKQIISAAGIMLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTR
                     NATVYNRHGVKVGHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVV
                     NRIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINKKPFIKIADGEYVKALNVLTTV
                     TNH"
     CDS             complement(2463..4745)
                     /locus_tag="ctg142_4"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGEFKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSDLSDLPDKDVLALAGSATDKRNAGII
                     DIAIDEYLKENNIPAMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EAVEGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSRAALAELKKRGVRPIMLTGDNQR
                     TAAAVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTG
                     DGVNDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWS
                     LTKLARTAELTMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENW
                     NMARLAKIAFSLAAGWTVIGIAFVSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTR
                     KYFWQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIY
                     QPVMKNR"
     CDS             4874..5728
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     76.4; E-value: 4e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg142_5"
                     /sec_met_domain="LysR_substrate (E-value: 4e-30, bitscore:
                     94.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1e-24, bitscore: 76.4,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAEEKQITSAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGINAKTLTTE
                     RMMAVTVDPKFKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKHSNWITHLQLVWRKDQKVTPLMKRIIDS
                     LSR"
     CDS             5780..7009
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg142_6"
                     /sec_met_domain="Amidinotransf (E-value: 3.1e-106,
                     bitscore: 345.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEKQGVHVVYLEDLLAQSLTNEDVRTKFVDQLLEESNIKKEDSLHQ
                     LLMDYLIAMPVNEMVKQIIAGIRKNEIQNVTPSLADLAEDPDYPFYLNPMPNVYFTRDQ
                     QAAIGNGMTINGMTFRARRRESLFMETVLKHHPDFKNANIPIWRDRYTHGRLEGGDELI
                     LNNHVLAIGISQRTSAAAITDLAHSLFGHSSYDTILAIKIPHNHAMMHLDTVFTMINYD
                     QFTVHPFILDKSGKIDIYVLEQDDHGEIKITPETNLIKVLKNYLHLSEIDLIPTGGGDA
                     IAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGILVHEIHSSELSRGRGGPRC
                     MSCPLVREDL"
     CDS             7021..8061
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg142_7"
                     /sec_met_domain="OTCace (E-value: 1.3e-51, bitscore: 164.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 1.4e-48, bitscore:
                     154.8, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSLLKCKDYTPAELNYLIDFALHLKELKKENIPHE
                     YLKGKNIALLFEKSSTRTRSAFVVACNDLGANPEYMGAGEIHLGKKESIEDTAKVLGSM
                     FDGIEYRGFAQKDVEDLAKYSGVPVWNGLTDKWHPTQMLADFMTIKEKFGHLKGLTLAY
                     VGDGRDNVADSLLVAGSMLGVNVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIE
                     QGVKGANIIYTDVWVSMGENDWSERIKLLKPYTVTMKMMHMTGTSDDQLIFMHCLPAFH
                     DRTTKVGEEIYKKYGLSEMEVTDEVFNSQYAWQFTEAENRLHSIKAIMAATLGNLFIPS
                     VDEGSK"
     CDS             8064..8996
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg142_8"
                     /sec_met_domain="AA_kinase (E-value: 2.7e-36, bitscore:
                     115.4, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVALGGNAIEAGDNSAAAQEKQVEKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNPAMPLDTVVAMTQGSIGYWMQKALDDQFKHTNYSH
                     QAVALITQTIVNANDPTFKNPTKPIGPFYTFNEMQKQKIYHPEYTYKQDAGRGYRQVVS
                     SPKPVKIINAPVIDTLLKSKFVPIAAGGGGIPVVVKDDSLQGVAGVIDKDFSAVKLAED
                     IQADELVILTTVDNAYVNYNQPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDF
                     VEKTGKTAIITSLRNASKLDDGVGTIVYN"
     CDS             9013..9549
                     /locus_tag="ctg142_9"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNKGYDYKLLKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKPALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             9670..10836
                     /locus_tag="ctg142_10"
                     /transl_table=11
                     /translation="MKLKKNQDDLKQIASLIEYAFLKDSDLTTDSNFMTRYDHSAGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQK
                     ILVANLAPFSENFYRHYGFSNSIYQKEYGFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHTDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMVAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKILSCMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFIKGKVSFYDYF"
     CDS             10852..11013
                     /locus_tag="ctg142_11"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLSVVVSGINVVISLLIMLNKYQIRKDKKQIADE
                     GHAPLDEN"
     CDS             11016..11621
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg142_12"
                     /sec_met_domain="LysR_substrate (E-value: 5.1e-18,
                     bitscore: 55.2, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKNSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEDAVIKDFILLVKKVY"
     CDS             11698..11820
                     /locus_tag="ctg142_13"
                     /transl_table=11
                     /translation="MLERKLLPLSAMVLALGLSGLTTHVKAADTPLMVMVTERL"
     CDS             11817..12242
                     /locus_tag="ctg142_14"
                     /transl_table=11
                     /translation="VTVHKKMQGTWYSYDSNAHSGRKITFTAHTVNGKINYTQDKSIIS
                     DYFNGNIQDQAGFDRATKNWMSGQTTKMKNNLFYEINPWISFENWSLYRVMPQKINGKK
                     HNVLLYSSRYDGGNYYRSKKLAKQMKNYKFKKVDYHL"
     CDS             12455..13018
                     /locus_tag="ctg142_15"
                     /transl_table=11
                     /translation="MLNAKNALFMQSGHEDQRKYKNYLIESYQNDDAYQKHESLSQVQQ
                     FERDLKDIVNSQVKVKLYPEFISTKPEKLAITHDNQYVVYLTEIGVQLGKGDEFANAVM
                     KEMKTAVEKEDGILAMIAGTIMNQPNEWFSLEVYKTEETYEEYHKTKHFKKYLEATKYV
                     VESKGLHLLKPDCIMDQGEIFYRP"
     CDS             13297..13443
                     /locus_tag="ctg142_16"
                     /transl_table=11
                     /translation="MNDFTKNMAQALFNQDKVNDFLRKEIQTAVNQLLEAELTAFLGYD
                     PYAK"
ORIGIN
        1 ttctgtctcg aaacacatta ctgaagatgt atgaaaggat cgaccaaagt gggattcctt
       61 tggacttgcg gagcccacat ctacggagaa gctccataac tttgtagtcc ttgaagaact
      121 tttcaacaga acgggcaatt ttaggttcgt tttcagtatc gaatgatggt aaactagaca
      181 tagcgcaagc ctttcgtttg atttcgtttg atattgatga tgttttgatc gacttaatta
      241 tatcaagcga acaaaggcct tgtgcttttt tattggctaa attattgaat tttcaaggta
      301 caagcccact tttgtaagtg ggaagtttaa gtcattaatt aaaagggtac atttatctaa
      361 gtccttctca aaaattttct ttaattcttg agttaaagca gggttgtagt tgaatgagtt
      421 tacctcaaag tttaatgtat agcttcggaa atcttgattg gcggaaccaa ctgaaaaaat
      481 attagaaccg ctaaccatag tttttgcatg aataaaacca tcattatatt tgtatacttt
      541 aacgccaagg gctactaaat acttagcata gtattctgta gcacgataaa caaatggatg
      601 atcgggcatg caacgaacca taattcgaac atcaataccg ctgttagcag cgataattaa
      661 ggcttcaaga attgattctt cgggaattaa ataaggcgtt tgaatataaa tgtatttttt
      721 agctcctgca ataattccct catagcctcg tctgatgccg taatgttgat tatcaggtcc
      781 tgaggaaaca atttgcatag cgacattttt attatcattg atatcttttc gattgacagt
      841 aaatggttta agttccttta attcaaattt aggtaaattt gttcttctga ttgacgtgtt
      901 ccagtccatt gcaaaccgga cctccattag aattggtgat tgcccaatta cacgtaaatg
      961 ggtatcccgc caatgaccga attttggtga tttattgaca tattgatctc caatattaaa
     1021 tccgccaata tagccaatat ggtggtcaat aataactaat tttctatgta agtggtaatt
     1081 gagtcgtggg gtagtaaacc agtgcttttt tgaagtggaa ataaatggtt gagcttcgcc
     1141 gcccaattct cttaaatggt caaaaaagct tggcttagtg cctcttgatc cagaggtatc
     1201 atacataaat tactcttacc ttagcaccat tagctgcagc ctcttccaag gcttttaaag
     1261 cacgatgccc taattagtca gaataaaaag tataaaattc taagctgaca gattttttgg
     1321 catttttgat atcagtaatc atttggtcaa aaagttctgg tccagaaata aatactttga
     1381 cctgattatc gaaagttaaa atcgcatcat cgttgttaag atttagttcc gacagcattc
     1441 ttactcgtgg aagacgctct ttttcaggta gaagatcgtg ctctttaagc atgtcgcgtt
     1501 gctcagctaa ataatgtctt tgtacctttt tttgctcttc ttgaatagca aagatttcat
     1561 catgtgaaag ctgacgacca aagaaaagat ataggataaa accgatactg ggcagaacgg
     1621 ttaatacaag catccatgcc caagttgcaa caacgctgcg gcgacttcta aagaccgtcc
     1681 atacatattg ataatccata agacttcgat agtcctacgg attatatccc aagttaaaat
     1741 catgaataat tactcccttg taagtagtgt tataaataat tttagcagaa ttaagcaaat
     1801 agttataaaa cagatgagta aaaaatgctt ccaattcgat aatttttgat aaaataaggg
     1861 atggagaatg gtataaacac tacgggggtg gattatgttg agaaaacaaa ttatttctgc
     1921 tgcaggtata atgttagcag ttattggatt aggcgcagca actacacaaa gcgttgatgc
     1981 agttgttact aatccagtta gacaaggtaa gagattaaat ctaactagaa atgctactgt
     2041 ttataataga catggtgtta aagttggaca tttaagaaag ggaaagcttt acaaagtacg
     2101 tgccataaaa gtaattaatg gtaatactta tgtaaagatt cgtaaaaata gatttgttaa
     2161 ggaagaagcc ttcttgccat atatgaagac tactgtaaaa gtagttaata gaatcaaaaa
     2221 gcattccttt gtttatgatg agaatggtga aaaaatccca ggcaaatttt taaagcgtgg
     2281 tgctaaggtt aactatttag gccataaaga aattaataaa aaaccattta tcaaaattgc
     2341 tgatggtgaa tatgttaagg ctttgaatgt cttgactaca gttactaatc attaatcaaa
     2401 aaaacactct gaaaactaca ttactacaat gtagttttca gagtgttttt gttttaagtt
     2461 aattatctgt ttttcattac tggttgataa atcaaatcaa taataattgc tgcaattaat
     2521 gcaaccacaa cggtaattaa taagttttgc caactaattt gagccattgc taaaccgcat
     2581 aaagctaaaa taaaggttaa tgcgacatcg gcaatttgaa caatacctac aagtttagat
     2641 gggtaatctt gccagaagta tttacgagtt ctagtaatta atacaattaa cattgcactt
     2701 agaactaagt aaacatagac catggtagag atagaattgt gactccagcc atgcatgttg
     2761 aggtagctga caaaagcgat accgataact gtccaacctg cagcaagaga gaatgcgatt
     2821 ttggctaacc ttgccatatt ccaattttct ggtttgtaag taatatgggt acggtccgta
     2881 ccaatcatca tggtaaccat gttattcatg attgtgtaaa taaccatagc atttaatgcc
     2941 attggaatat agttgaagaa gagatagccg aaggttaaaa gcatagttaa ttcggcggtt
     3001 ctggcgagct tagtaagtga ccaagtagtc attcgttgat atacacggtg accagcatca
     3061 agaattttaa caatagagct taagccatca tctagaagca ccatcttact tgaacgcttg
     3121 gcaacatcgg cagcgttaga aacagcaata ccaacttcag cttgctttaa agcaggagag
     3181 tcgttaacac catcaccagt cataccaacg atataacctt tttcttggaa gaatttaacc
     3241 atcttaagtt tatcttcagg taaaacatcg gcaatccctg ctaattcatc aatatcggtg
     3301 ctttcatcaa agtcatgaat agagataacg ttaccagtta aatcaacttg ttcagcgact
     3361 gctgcggcag ttctttgatt atcaccagtt aacatgattg gacgtacgcc ccgtttttta
     3421 agttctgcta aagcagccct agagtccttt cttactttat cttgtaaaat aaatactccc
     3481 gcaagtttgt catcaattaa cacggcaact gagcgtccag ctttaaaatt gatgccttca
     3541 actgcttcaa ctgcttcatt tgcattctta tcgattaatg aaagttgctt aaatgaacct
     3601 aacttaacat tgtgaccatc tacttcagcc atagaatagc cagtgtcaga agtaaatggg
     3661 gtaaagtgtt caacgtccat ggcagggata ttattttctt ttaagtattc atcaatggcg
     3721 atatcaatga tacctgcatt gcgcttatca gttgcactac cggctaaagc aagtacatct
     3781 ttatctggca aatcgcttaa atcgctccaa ctagcaactg cagttttgtt ttcagtgatt
     3841 gttcccgtct tatcaagtaa aagcaagttt aagttagctg catcttggat accagttaaa
     3901 tcagctgtta agacgccttc tttacttaaa cgggttgctt caaatgaatt ggacaatgca
     3961 aaggttgacg gcatcgcaac cggaattgaa gcgatgaaca tcatggctaa gaatggcaac
     4021 atgttgataa acgtatcaaa attaccaccc ttaaagaatg aagcaatgat aataactaag
     4081 gtaagtacac cgtcaagtag gcaaaggtag taaataatct tagttaaaag ttgttgcaag
     4141 tgaccaggtg cagctgaatt gttgatcaag ttaatggtct taccacttct tgaatcttta
     4201 ccagttgcag taacaattgc taatccatcg ccttcaacaa cagtagtacc agcataagct
     4261 gtgtcatcaa tgttcttttt aacgggcttg aattcaccgg taattgagct ttcatcacag
     4321 gcgatcttac cgctaaccat ttttacatcg gctgcaagta catctccacg ttgaagtgag
     4381 attaagtcgc ctctaactaa ttgcttagag tcaattttga tccacttacc atcgcgttct
     4441 acagccacct taggggttag cttatgtgaa atggtattta atacccgccg tgactgtttc
     4501 ttcttggatg caccgttaaa agccgcaaaa agaagcatca acaagacgaa caaagattga
     4561 atccatttgc ctaagataca ttcgaggatt aaggcacctt ctagaatcca ggcagaaaga
     4621 ttccataatt ttgatagaaa ttccttaaaa aagttgtatt cgggttcagg tacttcgttt
     4681 aacccatctt ctttaagtct cttatctgct tcggcttgag ttaagccatg aaatttttca
     4741 gacattttat tccctccaaa tctaccttaa taaagtagca catatgttgt ttgaatgaaa
     4801 atactaaatt aaaatataag atatagaaat ttttaataag agatacaact aaaataaaaa
     4861 ggatagatta ttaatgaata ttaaacaatt acgctacttt ttagtagtag ccgaagaaaa
     4921 gcaaatcact tcagcagcta aaagactata cattgcacaa ccgccgctga gttatcaatt
     4981 aaagcaacta gaaaaagaac taggagcaca attatttaag cgtactgctc atggaattga
     5041 attaacagat gctggacaaa ttttgcagag ctatgctagt gaaattctct ctttatcaga
     5101 aagcgtgaaa aatcaggttc ataaaactgt ttcaggtgaa ctaggcacga ttgcaatagg
     5161 catggcttca tcatcaactg gactaattcc tatgaaaagt tttcaagatt taactaagtt
     5221 ttatccggaa atcaactttg atatttatga agataatacc tttggcatta tcgataaatt
     5281 ggaaaagaag acaatcgatt taggaattgt gcgtacgcct tataatcgta atggcataaa
     5341 tgcaaaaact ttaactactg aaagaatgat ggcagttact gttgatccca aatttaagga
     5401 taagacggaa ttaaggatta aagatctaaa tgagcagccc ctcattattt atcgaagatt
     5461 tgaagaaatt tttaaccaga cttttgctca tcatgggatt aagccgtttt atgctgttaa
     5521 atgtgatgat tctagaacag cgattacttg ggcgaagaga aaaatgggga ttgctcttgt
     5581 tcctgaatct attgcttcta cgtatgcacc tgatgatctt attcctatta aacatagtaa
     5641 ttggattacg catttgcaat tagtgtggcg caaggatcaa aaggtgacgc ctttaatgaa
     5701 gagaataata gattcactaa gccgttaaga ttgtaacttc tacctaattg atccataatt
     5761 tgaattaaga ggcgatataa tgactgactt aattcatgtt tattccgaaa ttggcaaatt
     5821 agaaacagtt atgctgcatc gaccgggaag agaattagaa aatctttcac cggatatctt
     5881 aaatcgaatg ttaattgacg atattccata tttaaaaata gctcaaaaag agcatgacta
     5941 ttttgcccac actttggaaa aacagggagt tcatgtcgtt tatttagaag atttattagc
     6001 tcagtctttg actaatgaag atgtccgtac aaaatttgta gatcaattat tagaagaatc
     6061 caatataaaa aaagaagatt cattacatca attactgatg gactatttaa tagcaatgcc
     6121 agtaaatgaa atggttaagc aaataattgc tggtattaga aaaaatgaaa tacaaaatgt
     6181 aactccttca ttagccgatc tagctgaaga tccagattat ccattttatt tgaatccaat
     6241 gccaaatgtg tattttactc gtgatcaaca agcagctatt ggtaatggca tgactattaa
     6301 tggaatgacg tttagagcta gaagacgtga gtcattattt atggaaaccg ttttaaagca
     6361 tcatcccgac tttaaaaatg ccaatattcc tatttggcgt gatcgttaca ctcatggacg
     6421 tttagaaggt ggcgatgagc tgattttaaa caatcatgtt ttagcaatcg gtatttctca
     6481 aagaacttcc gctgccgcaa tcactgacct tgctcatagc ctgtttggtc attctagtta
     6541 tgacacaatt ttagcaatta aaataccaca taatcatgcc atgatgcatc tggatacagt
     6601 ctttacaatg attaattatg atcagtttac cgttcatcct tttattttag acaaatcagg
     6661 aaagattgat atttatgttt tagagcaaga tgatcatggt gagattaaaa ttaccccaga
     6721 aactaatttg atcaaagtgt taaagaatta tttgcactta tcggagattg acctaattcc
     6781 aaccggaggt ggggatgcaa ttgcagcccc aagagagcag tggaatgatg gctcgaatac
     6841 tttggctatt gcgccaggtg aagtcgttac atatgatcgt aattatgtat caaatgattt
     6901 gttaagaaag catggcattt tagttcatga aattcattca agtgagcttt ctcgtggccg
     6961 tggaggtcca agatgtatgt catgtccact tgttcgtgaa gatttgtaag aggcgtcaaa
     7021 atgaaatatt tacaaaatgt gtttcaaggc agaagtttat taaaatgcaa agactatact
     7081 ccagcggagc ttaactatct aattgatttc gcacttcatt tgaaggaact aaagaaagaa
     7141 aatattccgc atgaatattt aaaaggaaag aatatagctc ttttatttga aaaatcttca
     7201 acaagaacac gttcagcctt tgtagttgca tgcaatgatt taggtgcaaa tcctgaatat
     7261 atgggtgctg gtgaaattca tttaggtaaa aaggaaagta ttgaagatac tgcaaaggtt
     7321 ttgggcagta tgtttgatgg cattgaatat cgcggttttg ctcaaaaaga tgtagaagat
     7381 ttggctaaat attctggtgt ccctgtttgg aatggtttaa cagataaatg gcatccgacc
     7441 caaatgttgg ctgactttat gactattaaa gaaaagtttg gacatttaaa gggacttact
     7501 ttagcttatg taggtgatgg acgtgataat gttgccgaca gtcttttagt ggctggcagc
     7561 atgcttggag ttaatgtaca catagttacg ccaaagcctt tattcactca ccctgatgta
     7621 caaaaaattg cagaaggttt tgccaaagat tctggatcaa gaaatttgat tactgatgat
     7681 attgaacaag gcgttaaagg tgcaaatatt atttatactg atgtctgggt atcaatgggt
     7741 gaaaatgact ggagtgagag aatcaaattg ttaaagcctt acacggttac aatgaagatg
     7801 atgcatatga caggcacctc ggatgatcaa ctaatcttta tgcactgttt gcctgcgttt
     7861 catgatcgca ctactaaagt tggcgaagaa atttataaaa aatatggtct aagtgaaatg
     7921 gaagttacag atgaagtctt taactctcaa tacgcttggc aatttactga agcggaaaat
     7981 agattgcatt ctatcaaagc aataatggcc gctactttgg gcaatttgtt tattccgtca
     8041 gttgatgaag gaagtaaata aagatgaaaa gaatagttgt agctttgggt ggcaatgcta
     8101 ttgaagcagg tgataatagt gcagctgccc aagaaaagca ggttgaaaag acaatgaagg
     8161 ttgttgctaa aatgattgaa aatggtgatc aggtagcgat tgttcatggt aatggcccgc
     8221 aggttggtaa tttgcttttg caacaataca aaggttcaag taaagataat cccgctatgc
     8281 cgcttgatac agtagtagca atgactcaag gcagtatcgg ctattggatg caaaaggcct
     8341 tagacgatca atttaaacat acaaattatt cacatcaagc tgttgcttta attactcaga
     8401 caatagttaa tgcgaatgat ccaactttta agaatccaac taaaccaatt ggcccatttt
     8461 atacatttaa cgaaatgcag aagcaaaaaa tctatcatcc tgaatatact tataagcaag
     8521 atgcaggtcg aggctatcgt caagtagttt cttctccaaa gcccgttaaa attattaatg
     8581 caccagtcat tgacacttta ctaaagagca agtttgttcc tattgctgcc ggaggtggtg
     8641 gaattcctgt tgtagtgaaa gacgatagtt tgcaaggcgt agcaggagta attgataaag
     8701 acttcagtgc cgtaaaacta gctgaagata ttcaagcaga tgaattagtt attctaacta
     8761 ctgttgacaa tgcctacgtg aactataatc aacctgatca agctcctatt ggaaaaataa
     8821 agattgatca attaaagaag tatctagaag ctggccaatt tgccgcaggc agcatgaagc
     8881 caaaaattga agctgtcatt gatttcgtag agaaaacagg aaagactgca attattactt
     8941 ctttaagaaa tgcaagtaaa cttgatgatg gagtaggtac aatcgtttat aattaactgc
     9001 ggtgagatat aaatgaacat ttttcaagaa ggaaatccgc aaaatattgc tcaggtatta
     9061 gctggaaaag attatcgtgt agctttgcag caagctattt ttaaaaagta tcctgatgcg
     9121 actttggttg atataaactt aaatatcccg gggccaatta aaaataatcg atatttaatc
     9181 aaattatttg attacggaat taaacaatta gaagaaatat ggcagaataa gggatatgac
     9241 tataaattat taaaagcatt aaataatgat gctggatgtg aaaatttcta tgttttgcga
     9301 gaatctagca aagtagttaa attatctaca attttatttg aagaaaataa taaaatagga
     9361 cgattatttg atgccgatgt attaattaaa gggaaacctg cactttcacg ccaagagctt
     9421 gaatactcta gtcgccgctg ctatttatgc aatcgccctg ctaaagagtg tgctcgatca
     9481 cggcgacact cagtagaaga gatgcaaaga tacatttcta gtttatatgc gaagtatgta
     9541 aataattaaa acgggatggg aggctaatca tcccgttttt tcatttaaat ctaaaaaaaa
     9601 gctaacgaaa aatgcataaa atgttctaaa atataagtaa agttatgaat atatattgta
     9661 aggaaaacta tgaaattaaa gaaaaaccaa gacgatttaa aacaaattgc ttcattgatt
     9721 gaatatgctt ttttaaaaga ttctgatttg actacagata gtaactttat gacccgatat
     9781 gatcatagtg ctggatatgg atattttgat caagaaaaat tgaccagtta tatgatggtc
     9841 aataagttta aagctgagat atttggtcat catgttccat tggcaggtat tggttatgtg
     9901 gcatcatatc ctgaatacag aggacgtgga catatatcta aattaatgaa agaaattctt
     9961 tttgatttgc atgatcaaaa aatcctagtt gcaaatctag ctccattttc agaaaatttt
    10021 tatcgtcatt atggttttag caatagtatt taccaaaaag aatatggctt ttcgggggct
    10081 gcacttgctt ctttcagatt accacgcaaa ggtaagataa ttcgtggaaa atggaatgat
    10141 ttgattgttc aaaatggtgt gattcaatta tatgaacgtc agttgcatac tgacgatgaa
    10201 agaaatacga tcatcagaga agcttggtgg tggaatagat tagatgatta ttatcatcat
    10261 cgagagattg ctgtttactt cgatgaagct ggtcggccga tgagctactt gatttatcgc
    10321 ataattgata actgttttat ggctgatgaa ttatattcaa ttacgcctca aggattatta
    10381 agcatattag gctttatggt agctcatata gggtcaatta aagagttttg tatgacattg
    10441 cctgagaagt ctttattggc tgaacttttt ccagagcaaa atgaattgga tattcaactt
    10501 catccatata tgatgagtag aattattgat ttccaaaaaa tcttgtcatg catgcgccca
    10561 ttgcaagagg gtacttttaa catcgaagtt aattatgatg atcagtgtcc atggaatatt
    10621 ggcgtttggc aattaactaa ttatgatcac caagttaagt gtgaacgaaa agaagatgaa
    10681 ctagttgatt tctctggtcc aattacaaca tggactcaaa tcttattagg acgtttaact
    10741 atggaatccg caattaaact tggtttgatc acagattatc gaattaaaaa gttggacttt
    10801 ataaaaggta aagtctcatt ttatgattat ttttagaaga aggtatctaa aatgagtaag
    10861 caaaagaaag ttagattact aaaattttta agcgtggtag ttagtggaat aaatgtggtt
    10921 atttcgctat tgattatgct caacaaatat caaattagaa aagataaaaa acaaatagca
    10981 gatgaaggtc atgccccatt ggatgaaaat taactatgaa aaaattgaga atagcatact
    11041 ttaaccaact tggtagaaga caattagatc gaattgtaga ccaatttaag caaaaaaatt
    11101 ctgatgtaga aattgaatta attggaatgg gacacgatga agcttttgat aaattagcca
    11161 aaaatgaagt tgatttagcg attagtgatt tgcgcgatga tcagctcgat tttaagaagg
    11221 aaatcttagg tcaggaagca gtaatggcta ttttgcaaaa gggtagttat cctagcggtg
    11281 ttcagatgat caataaagat gatctagctg atttaacctg ttttattgta gctaagcctg
    11341 aagaagaggc tgcagaactc catttattta aagatattta tcagattaga agcccattca
    11401 ttgcttcaaa ttccgtagaa gaggcagcat tgttagtagc ttctggatca ggatattttt
    11461 taatgaatga agcaaccgcc agtttaatta gtaatgatac tttacaacga ttgtttttat
    11521 tgtctaatgg acaacaaatg tggcaaaaga ttgcagcttt ttataccaat gaagatgcag
    11581 taattaaaga ttttattttg ttagttaaaa aagtatatta atctatcttg gaacagcaaa
    11641 atactgtaaa attaataatg aaagcgaatc cataatttta caactggaga tgattttatg
    11701 ctagagagaa aattattgcc tttgtcagcc atggtactgg ctttaggctt gagcggatta
    11761 acaacgcatg taaaggcagc tgacacccca cttatggtaa tggtaacgga gcggttgtga
    11821 ctgtgcataa gaagatgcag gggacatggt actcatatga tagtaatgca catagcggta
    11881 gaaaaattac ttttactgcg catacggtta atggaaaaat caattacact caagacaaat
    11941 caattattag cgattacttt aatggcaata ttcaagatca ggctggcttt gatcgagcta
    12001 ccaaaaattg gatgtcaggt caaacaacta agatgaaaaa taatctattt tatgagatta
    12061 atccatggat tagttttgaa aattggagtc tatatagagt aatgcctcaa aagattaatg
    12121 gtaaaaagca taatgtttta ctgtattcaa gtagatacga tggcggcaat tactatagaa
    12181 gcaagaaatt ggctaaacaa atgaaaaatt ataagtttaa aaaggtagac tatcatttgt
    12241 aaaatttaat atagaagaaa agcttcaaat tatagaaatt atgttaagtt gattttggca
    12301 gtaacttttt tgaaaaaata gtttataata tcaataaaaa ttaatttggt aggaataaaa
    12361 aataaaatta gagaatgcac ctgttttaaa tttatttaga ttagaaataa atcctgaaaa
    12421 gcatgaaata tatactaaaa aagtggaaaa gtatatgtta aatgcaaaga atgcattatt
    12481 tatgcagagc ggtcatgaag atcaaaggaa atataaaaac tacttgatag aaagttatca
    12541 aaatgacgat gcttatcaaa aacatgagtc tttaagtcaa gtccagcaat ttgaacgtga
    12601 tctgaaagat attgtaaata gtcaagttaa agtaaaatta tatcctgaat ttatttcaac
    12661 taagccagaa aagttagcta ttacgcacga taatcaatat gtggtttatt taactgaaat
    12721 tggtgtgcag ttgggtaagg gcgatgaatt cgccaatgca gtaatgaaag aaatgaaaac
    12781 tgcggttgaa aaagaagacg gcatcttggc aatgattgct ggtactatta tgaatcaacc
    12841 gaatgaatgg ttttcattag aagtatacaa aactgaagaa acatacgagg aatatcataa
    12901 gactaaacac ttcaaaaaat atctagaagc taccaagtat gtggtagaaa gtaaaggtct
    12961 tcacctactt aaacctgatt gtataatgga tcaaggagaa attttctatc gaccataaga
    13021 aaaagcaagt tatttagttg aaaaataact tgctttttga attatttgca attgtttcga
    13081 ttctttactt taacagggag aggcttatta actaacgtag agctgatagc catgattcct
    13141 gcagttgcta acgcaactgt aatggagacc gtaaaatagt ttgtgtaagg atgaatgatt
    13201 ccttaaatta atttctgaaa acattagaaa aaggagttcc tttctcgtat gattggattg
    13261 aacaaaaaaa caacatacag aaagaagaac tccttcatga atgattttac caaaaatatg
    13321 gctcaagcac tattcaatca agacaaagtt aatgattttt tgcgcaagga aattcaaact
    13381 gcagttaatc aattgcttga agctgaattg actgcctttt taggctatga tccttatgca
    13441 aaa
//
