LOCUS       gnlProkkaPNKMBPKI_67   13560 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PNKMBPKI_67.
ACCESSION   gnlProkkaPNKMBPKI_67
VERSION     gnlProkkaPNKMBPKI_67
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 06:49:18
            Original ID  :: gnl|Prokka|PNKMBPKI_67
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 176917
            Orig. end    :: 190477
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13560
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:8560]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8560
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..13560
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13560
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3971..4489
                     /locus_tag="ctg44_157"
                     /transl_table=11
                     /translation="MSQQQEYWFAARTRKDQELTTRDALEKIGVEYFLPTQFVIRQLKY
                     RRRRVEVPVIRNLIFVHATKEFACAIANEYGVRLFYMRDFDTKSMLIVPDKQMKDFMFV
                     MNLDPAAVILNDDCFAVGTKVQVIKGDFCGVEGELASLSNRTYVTIRIRGVLSASVKVP
                     KSYLRILAP"
     CDS             4525..4998
                     /locus_tag="ctg44_158"
                     /transl_table=11
                     /translation="MTQIHELQHVAHELLYLGADGSPIYTDSFRQLNTEVLQKSDALFA
                     LKGENPEEEARLCLALLMGYNATIYDYGDKESKKQVILDRSLLVLESLPSSLLKCQLLT
                     YCYGEVFEEELAKEAHAIIDGWKDRELLEEEREIVENLRILEEPPYLFSNKSC"
     CDS             5001..6302
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 200.2;
                     E-value: 7e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_159"
                     /sec_met_domain="CTP_transf_like (E-value: 2.9e-15,
                     bitscore: 50.2, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 4.9e-118, bitscore:
                     386.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.2e-63, bitscore:
                     207.4, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKVYVGMSADIIHPGHLNIIHEAQKLGNVTVGVLTDAAIASYK
                     RLPYLTYEQRSLIVQNLKGVDEVIPQTTLDYIPNLELLKPDFVVHGDDWKEGVQKETRQ
                     RVIETLSKWGGQVIDIPYTQGISSTKLNSKLKEIGTTPEVRLKRLKRLIEAKSIVRICE
                     SHSGLTGLIIENTSVEVNGMKREFDGMWSSSLTDSTSKGKPDIEAVDLTTRLHDLNDAL
                     ECTTKPVIFDGDTGGKIEHFVFTVRTLERLGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCDKISAGKRAQITDDFMIIARIESFIAGKGLDDAMKRALAYIEAGADGIMIHSKD
                     KSGEDIRLFCKALREVNQSIPIVVVPTTYNHITDEELSTWGINVVIYANHMLRSAYPAM
                     LNTAKSILLHARSYEANDLCMPVKDILELIPGTK"
     CDS             6310..7437
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 67.9;
                     E-value: 1.2e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_160"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.6e-18, bitscore:
                     59.2, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9e-21, bitscore:
                     67.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPELFINSLVQNELDFFTGVPDSLLKHICAYITDHIASNSHIV
                     AANEGAAIGLAVGYHLATNKIPVVYMQNSGIGNSINPLLSLVDKEVYNIPLLLLVGWRG
                     EPGVKDEPQHIKQGKVTIPLFDSMRIKNQILSKDKSDFLQQLNVALEYIRETNEPFVFI
                     IQKETFSDYKLQTPNNNALLLDRETAIKIIVSSISKNDIVVSTTGMISRELFEYRDNMG
                     ESHEKDFLTVGSMGHASQIALGIALQKKARTVYCFDGDGAVLMHMGGLTTIGSIKPSNY
                     IHVLFNNGAHDSVGGQPTVGFEVDFTKIALACGYKYALVVESASSLNEVLKTVNEMQGP
                     VFLEVKVKKGARKDLGRPTITPIQNKDSFMDFLKR"
     CDS             7439..8560
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_161"
                     /sec_met_domain="Fe-ADH (E-value: 4.1e-84, bitscore: 275.8,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQRIYIGEASLNNLDIILQEYSAKKVFLVRGKKSYELCGAQSRL
                     NSILKKVGVQIFEFHDFEENPKIEDLDRGLLQLRVYHPDLILAIGGGSVLDMAKLLRFF
                     YSYSGNKIGRVFEKIENLLPLIVIPTTAGTGSEATSFAVLYKNKVKYSVSHEDILPEIA
                     FIDPYFTYNISRYLTACTGFDALAQAIEAYWNLNATNESDVFAVKAIKLLWPNLPLAVN
                     NPTKEVRNSMSEGAYWAGCAINITKTTAPHAFSYPFTTYYGYPHGHAVALTFPFFMEYN
                     VGSILLKHGTVFDKMIRLMEILNITNVNECKSLLCDYIENIGLDLKLPANFDHRIILSN
                     INVQRLSNNPVRIDGAVAKTALNTLCIKDDDKD"
     CDS             8566..9810
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_162"
                     /sec_met_domain="Polysacc_synt (E-value: 1.2e-36, bitscore:
                     120.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKSLDSYKVIFQNTFYLSIIEAIRLIMPFIALPYIITTIGAT
                     NYGIIIFSQTIVSYFSIVINWGLDVTSVREVSLNRGSLKKMSLIVSTVFTIKFILFGLC
                     FSIFMICLFFIPFFQQYRIIYLYAFLSCFSEVIIPVWFFQGIEKMKYLTYIRTTSIVLY
                     TILVFTFIKKEMDFTLLALLQSLANITAGVFSLILLLIFCRVKFVFPTFRVMKETFCNS
                     TPFFVSRVSFLLNTNIAKTMSGLFLNMHTVAAFDLSQKILSFVSVPIQMLNQAIYPHVA
                     KNPIKSFSVKMLYVIAALSLILSVLLFFLAPYIILYFSVQLYAEALIFIRILCLYVFCF
                     GINTYLGTPLLVAYGFYKPFNFSVIYSTLFVCSLYGILYVFNLLGGECFALAMFLTELF
                     ILIYRFYYCLKFKLI"
     CDS             9816..10601
                     /locus_tag="ctg44_163"
                     /transl_table=11
                     /translation="MEKISNYNTDGTMLRKQQERMFEMLCVIDDICVKNEINYWLSGGT
                     LLGAVRHGGFIPWDDDLDIQLMKDDYNKLLGLLKTELPEQYQLQTSKTDRNYFARYAKV
                     RDVNSLLEDSDYTLGYKYKGIFIDIFSVEKANKFLVKISAFMQWYLLISLLPMVHKKTK
                     MQLNLFSLWNKFLGTFYSGFRLFGKLFAKKINYSYGVYYPLNCDYTTIFPLTTIEFEGR
                     MFKVPGNYNLYLCNIYGDYMKLPPEEERENHNIRVVHIV"
     CDS             10616..11941
                     /locus_tag="ctg44_164"
                     /transl_table=11
                     /translation="MLIVILLTLILIYILYKIYKKKKVHQFLLIYFAFSAFLWVIFPSI
                     VSLIGDRYKQELVVKENVFITYAIYEFLFYIILLLLLYRFPLCKPFYYGKYIPNTSSSI
                     KRIWFVLSLFLIINIIKQISSNVTYSEVNDSTILAEQETNLFSIFSNFSICLYLTIILF
                     YNKLYSKRIIFFSWLLLSLNIITVLAHGARMQVIFYLFVFVYYLFSSALNKKRFFLYMS
                     FLIGIIYLCSYILPAVAYIRSGGNFTVEDLRKSYENYGEANAFVLQLLIKSNSINTGAI
                     LVEETKEKPYLNPYINSIYSFCPSILFPGKRPLAGSSDGTIDGFPTRLAAEYISGDSRF
                     FNVGISTSATALWHGGILFYVINLIIVFFWYRFLNSLMFYENYYAKLLVVYFTVLGYFI
                     LPTADVLIRDLLKQPFFYAFFIFISRGGLIKDWVRSLKRHIA"
     CDS             11970..12941
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_165"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.4e-37,
                     bitscore: 120.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNPILLSIVIPVYNVELYIERCLLSCLNQDLSISQYEIILIDDG
                     SPDSSIDKISKWLDRKNITLLTQPNSGLSVARNNGLLHAKGKYVWFVDSDDWILENCLQ
                     EIAGYMVAGIDIITFCAADFINDKFYRRFEYITGVNKKIEGRDLLKRGTCQHCVPFSIY
                     RKRFLEQNHLFFLPNIFHEDTEFSPRAYYLANHVFCINKVFYYVYHNPNSITRTFNPKK
                     SFDLLIVSHSLSIFMLDVTPEYKSCFNNLISLSINAAINGIVTAKSEISRFIVDLTARG
                     LYRNMLNAGKLRYKMEGLLLYLCPALLICLYKHYSSLRRIIK"
ORIGIN
        1 ccgcccaatc tggttcagtc ttttcatgaa ctggagaggg tgaaccgtac cgattggttt
       61 tgtacttccg acccggtagg taagaaactt ggttccggtg gtggaacatc ctggttgctt
      121 gaagaatgtt ataatgaata ttcagatggt gctacttttg gagagtggct tgaaaaagaa
      181 aaaagaattc ttcttcatgc gggtgggcaa agccgccgtt tacccggcta tgcaccttct
      241 ggaaagattc tcactccggt tcctgtgttc cggtgggaga gagggcaaca tctgggacaa
      301 aatctgcttt ctctgcaact tcccctatat gaaaaaatca tgtctttggc tccggataaa
      361 ctccatacac tgattgcgag tggtgatgtc tatattcgtt cggagaaacc tttgcagagt
      421 attcccgaag cggatgtggt ttgttatgga ctgtgggtag atccgtctct ggctacccat
      481 catggcgtgt ttgcttccga tcgcaaacat cccgaacaac tcgactttat gcttcagaag
      541 ccttcgttgg cagaattgga atctttatcg aagacccatt tgttcctgat ggacatcggt
      601 atatggcttt tgagtgaccg tgccgtagaa atcttgataa aacgttctca taaagaaagc
      661 tctgaagaac taaagtatta tgatctttat tccgattttg gattagcttt gggaactcat
      721 ccccgtattg aagacgaaga ggtcaatacg ctatccgttg ctattctgcc tttgccggga
      781 ggagagttct atcattacgg gaccagtaaa gaactgattt cttcaactct ttccgtacag
      841 aataaggttt acgatcagcg tcgtatcatg caccgtaaag taaagcccaa tccggctatg
      901 tttgtccaaa atgctgtcgt gcggatacct ctttgtgccg agaatgctga tttatggatc
      961 gagaacagtc atatcggacc aaagtggaag attgcttcac gacatattat taccggggtt
     1021 ccggaaaatg actggtcatt ggctgtgcct gccggagtgt gtgtagatgt ggttccgatg
     1081 ggtgataagg gctttgttgc ccgtccatac ggtctggacg atgttttcaa aggagatttg
     1141 agagattcca aaacaaccct gacgggtatt ccttttggtg aatggatgtc caaacgcggt
     1201 ttgtcatata cagatttgaa aggacgtacg gacgatttac aggcagtttc cgtattccct
     1261 atggttaatt ctgtagaaga gttgggattg gtgttgaggt ggatgttgtc cgaacccgaa
     1321 ctggaggaag gaaagaatat ctggttacgt tccgaacatt tttctgcgga cgaaatttcg
     1381 gcaggtgcca atctgaagcg tttgtatgca caacgtgaag agttcagaaa aggaaactgg
     1441 aaagcattgg ccgttaatca tgaaaaaagt gttttttatc aacttgattt ggccgatgca
     1501 gctgaagatt ttgtacgtct tggtttggat atgcctgaat tattgcctga ggatgctctg
     1561 cagatgtcac gcatccataa ccggatgttg cgtgcgcgta ttttgaaatt agacgggaaa
     1621 gattatcgtc cggaagaaca ggctgctttt gatttgcttc gtgacggctt gctggacggg
     1681 atcagtaatc gtaagagtac cccaaaattg gatgtatatt ccgatcagat tgtttgggga
     1741 cgtagccccg tgcgcatcga tatggcaggt ggatggaccg atactcctcc ttattcactt
     1801 tattcgggag gaaatgtggt gaatctggct attgagttga acggacaacc tcccttacag
     1861 gtctatgtga agccgtgtaa agacttccat atcgtcctgc gttctatcga tatgggtgct
     1921 atggaaatag tatctacgtt tgatgaattg caagattata agaagatcgg ttcacctttc
     1981 tctattccga aagccgctct gtcattggca ggctttgcac ctgcgttttc tgctgtatct
     2041 tatgcttcat tagaggaaca gcttaaagat ttcggtgcag gtattgaagt gactttattg
     2101 gctgctattc ctgccggttc cggtttgggc accagttcca ttctggcttc taccgtactt
     2161 ggtgccatta acgatttctg tggtttagcc tgggataaaa atgagatttg tcaacgtact
     2221 cttgtccttg aacaattgct gactaccggc ggtggatggc aggatcagta tggaggtgtg
     2281 ttgcagggtg tgaagcttct tcagaccgag gccggctttg ctcaaagtcc attggtgcgt
     2341 tggctacccg atcatttatt tacgcatcct gaatacaaag actgtcactt gctttattat
     2401 accggtataa ctcgtacggc aaaagggatc ttggcagaaa tagtcagttc catgttcctc
     2461 aattcatcgt tgcatctcaa tttactctcg gaaatgaagg cgcatgcatt gaatatgaat
     2521 gaagctatac agcgtggaag ttttgttgag tttggccgtt tggtaggaaa aacctgggaa
     2581 caaaacaaag cattggatag cggaacaaat cctccggctg tggaggcaat tatcgatctg
     2641 ataaaagatt ataccttggg atataaattg ccgggagccg gtggtggcgg gtacttatat
     2701 atggtagcga aagatccgca agctgctgtt cgtattcgta agatactgac agaaaacgct
     2761 ccgaatccgc gggcacgttt tgtcgaaatg acgttatctg ataagggatt ccaagtatca
     2821 cgatcataaa aatagtattg gttgacgaga ggtaagggtt ttatctctcg ttgacttctt
     2881 tttccattcc tcattaagtt tgcctcttct gttattctga tagtaaaata gagattctga
     2941 tatctttaag tcggcttctt tcttgtttta aaaatcttgt tgtcttgaga aagtgatgaa
     3001 atagcaagtg atggagcatt aacttgtctt taattcgttt cttcatacgt gtactcttca
     3061 tacgaagtta acttcgtctt tgcaaaacat taacttcttg tgaagaagaa gttagttata
     3121 ggaaaatacg aagttaactt cgtatagtta cgaaattcat tttcattgaa aatcctccta
     3181 ctttttgcct ggcggtttca tttattgaac aaaaactata gaattctttt ctgtagcata
     3241 ggtcaatatg aatcattcct gaatgttatt ttggaggtat aggatgcctt ttccgttgct
     3301 tactgattga aattagtgca tgtttatcga tcttttgact ggtgatttga tttatttgct
     3361 ggagatatga ttttggtgaa aatagaatcc cggtattttt tataacaact tagtcagtgg
     3421 tccgtaaata agggattcct gagactactc aaaatacaat gtgacagaat gcttttggga
     3481 gtatatagtt tctaaatctt tatagataga ataatgaaga ctttatatta ttgtgtaatt
     3541 tgcttattat cagtatattg tgtggtaaat gcgaaaagga taaaaagagt gaattctctt
     3601 gtaattaact gatagtcagt agtgaatgtg tttcaaaaga cgttcgtctt ttgaaacatc
     3661 aattatggag ataaaagccc acatacaaaa taagtaaaaa gctgttttta ttaccagatt
     3721 attatctgat aatcagtaca taaagaagtc tatttagttt ttcatctaaa aatattttgc
     3781 acatcaaaat ttagtttata cctttgtgct attaaacgaa cgttttttga aacatcaatt
     3841 gatcgaatcc gttcgtttcc acctaaaata agtcataaaa aatcttgcag tttggctgag
     3901 aaaaagagtc tcacccaact gcgaagcata cccggactta agtaaatcac tcaggaatat
     3961 atccttctaa atgtctcaac aacaagaata ttggttcgct gcccgtaccc gtaaggatca
     4021 ggagcttact actcgtgacg cattagagaa aataggtgtc gagtattttt tgccgaccca
     4081 atttgtcatt cgtcaattga aatatcgccg gcgtcgtgta gaagttcctg tcattcgtaa
     4141 tcttattttt gtacatgcta ccaaagagtt tgcttgtgct attgccaatg aatacggggt
     4201 gcgtcttttc tatatgcgtg attttgacac taagagtatg cttattgttc ccgataagca
     4261 gatgaaagat tttatgtttg tcatgaatct cgatcctgct gctgttatcc tcaacgatga
     4321 ttgtttcgca gttggtacca aagtacaagt catcaaggga gatttttgtg gagttgaagg
     4381 tgaactggcc agtctttcta atcgtactta tgtcactatc cgaattcgtg gcgttttatc
     4441 tgccagtgtc aaggttccta aaagctacct tcgcattctc gcaccgtaat cagtaatatt
     4501 ttatcatata aaatgaatac tcttatgacc cagattcatg agctgcaaca tgtggctcac
     4561 gaattattgt atttgggtgc tgacggttct cctatctata ccgacagttt ccgtcaatta
     4621 aacactgaag tgcttcaaaa atctgatgct ttgtttgctt tgaaaggaga aaatccggaa
     4681 gaagaagcac gactttgcct ggctctcttg atgggctaca atgcaacaat ctatgattat
     4741 ggcgacaagg agtctaagaa acaggttatt ctggatcgtt ccttgcttgt gttagagtct
     4801 ctcccgtctt ctttgctcaa gtgtcagctt ttgacatatt gttatggaga agtttttgaa
     4861 gaagagttgg caaaggaagc tcatgcaatt atagatggtt ggaaagatcg agaattgtta
     4921 gaagaagaaa gagaaatagt tgaaaatttg aggattttgg aagaacctcc atatctgttt
     4981 agtaataaat cttgttagaa atgaaaaaga aagtatatgt tgggatgagt gctgatatta
     5041 ttcatccagg gcatttgaat attattcatg aagcacaaaa actagggaat gtgactgtag
     5101 gtgttttaac agatgctgct atagccagtt ataaacgttt accttattta acttatgaac
     5161 aacgttcctt aatagtacaa aatctaaaag gtgttgatga agttattcca caaactacct
     5221 tagattatat tcctaatctt gaattgctaa aacctgattt tgttgttcat ggagatgatt
     5281 ggaaagaagg cgttcagaag gaaacaagac aacgggttat tgaaactctt tctaaatggg
     5341 gcggacaagt tattgatata ccttatacac aaggtatatc ctcaacaaaa ctcaattcaa
     5401 agcttaaaga aatagggaca actcctgaag tgcgtttgaa aagattaaaa cgtttgattg
     5461 aagctaagtc cattgttcgt atttgtgaat cacatagtgg attaacgggg ttaatcatag
     5521 aaaatacgtc tgttgaggta aatggtatga agcgtgaatt tgatggaatg tggtctagta
     5581 gtttaactga ttcaacatca aaggggaagc ctgatattga agctgtagat ttgacgaccc
     5641 gtttacatga tttaaatgat gctttggaat gtacaacgaa acctgttatt tttgatggtg
     5701 atacaggagg aaaaattgaa cattttgttt ttacagttcg tacgttagaa cgtttgggta
     5761 tttctgctat aataattgaa gataaagttg gattgaaaaa gaattcttta tttggaactg
     5821 atgttattca gacacaagat acaattgagg gtttttgcga taaaatatca gcaggaaaac
     5881 gtgctcaaat aacggatgac tttatgatta ttgccagaat tgaaagtttt attgctggta
     5941 aagggttaga tgatgctatg aaaagagcat tagcttatat tgaggcggga gctgatggta
     6001 taatgattca cagtaaagat aaatcaggtg aagatattag acttttttgt aaggcgttac
     6061 gagaggttaa tcaatcaatt cctatagtag tagttccgac aacttataat catataacag
     6121 atgaagagtt gtctacatgg ggtataaatg tggtcattta tgcaaaccat atgttacgta
     6181 gtgcttatcc tgctatgcta aatactgcga aatctatatt attacatgcc cgttcatatg
     6241 aggcaaatga tttatgtatg ccagtaaaag atatattaga attaatacca ggtacaaaat
     6301 agttttttta tgatttctcc agaacttttc attaactctc ttgtacaaaa tgaacttgat
     6361 ttttttacag gggtaccaga ctcattattg aaacatattt gtgcctatat aactgatcat
     6421 atagcttcaa atagtcatat agttgctgcc aatgagggag cagcgattgg tttggctgtt
     6481 ggttatcatt tggcaactaa taaaattccg gttgtatata tgcaaaattc cggtattggt
     6541 aattctatta atcctttatt atctttagta gacaaggagg tgtataatat tcctttatta
     6601 ttattagtcg gttggagagg tgagcctggt gtaaaggatg aacctcaaca tataaaacaa
     6661 ggtaaggtaa ctattccttt gtttgattct atgcgaataa agaaccagat actttccaaa
     6721 gataaatctg atttcttaca acaactaaac gtagcattag aatatataag agagacaaat
     6781 gagccttttg tttttataat tcagaaagaa acattcagtg attataaact gcaaactcca
     6841 aataataatg ctttgttatt ggatagagaa actgctatta agattattgt ttcttctatt
     6901 tctaagaatg atatagtcgt ttctactaca ggaatgatat ctcgtgagct atttgaatat
     6961 agggataaca tgggcgaatc tcatgaaaag gactttttaa cagtcggttc tatggggcat
     7021 gcctctcaaa tagctttggg tattgcatta caaaaaaagg ctagaactgt gtattgtttt
     7081 gatggtgatg gtgctgtttt aatgcatatg ggaggactaa caaccattgg atcaataaaa
     7141 ccgtctaatt acatccatgt attatttaat aatggagcgc atgattctgt aggtgggcaa
     7201 cctacggttg gttttgaggt agactttaca aagatagctt tggcgtgcgg ttataaatat
     7261 gctttggttg tggagagtgc ttcatcttta aacgaagttc ttaaaacggt gaatgaaatg
     7321 caaggacctg tttttttgga ggttaaggta aagaaaggtg ctcgaaaaga tttaggtcgt
     7381 cctacaataa ctccaataca aaataaagac tcttttatgg actttttaaa gcgataatat
     7441 gaaacaacgc atatatattg gagaggcctc attgaataat ttagatatta ttttgcagga
     7501 atattctgca aagaaggttt ttttggtgag agggaagaaa tcatatgagc tttgtggagc
     7561 acaatcaaga ttaaactcta tattgaagaa agtaggagtt cagatctttg aattccatga
     7621 ttttgaggaa aatcctaaaa tagaagattt agatagagga cttttgcaat taagagttta
     7681 tcatccagat ttgatacttg caataggagg aggcagtgta ttggatatgg ctaaattgct
     7741 tcgttttttt tattcttatt ctggaaataa aataggaaga gtttttgaaa aaatagaaaa
     7801 tctattacct ttaattgtta tacctacaac tgcgggaact ggcagtgagg ctacgagttt
     7861 tgctgtgtta tataagaata aagttaagta ttctgtttcg catgaagata tattacctga
     7921 aatagctttt attgatccat attttacata taatatttct cgatatttga cagcttgcac
     7981 ggggtttgat gcattggccc aggctattga agcttattgg aatttaaatg ctacaaatga
     8041 atctgatgtt tttgcagtaa aagcaataaa attactttgg cctaatttac cattagcggt
     8101 aaataatcca acaaaagagg ttagaaacag tatgtctgaa ggggcctatt gggctggatg
     8161 tgcaataaat ataacgaaaa ctacagcacc tcatgctttt tcttatccat ttactactta
     8221 ttatggctat ccacatggac atgcggtggc attaactttc ccatttttta tggaatataa
     8281 tgtaggaagt atattattaa agcatggtac agttttcgat aaaatgattc gattgatgga
     8341 aatactcaat ataaccaatg taaatgaatg caaatcttta ctatgtgatt atatagaaaa
     8401 tatcggactt gatttaaagt tgcctgccaa ttttgatcat cgaattattc tttcaaatat
     8461 aaatgtgcaa aggttgagta ataaccctgt acgaatagat ggggctgtgg ctaaaacagc
     8521 tttaaatact ttatgtatca aggatgatga taaagattga tagtgatgaa aattaaaaag
     8581 tctttagatt cctataaagt aatttttcaa aatacatttt atttgtcgat aattgaagct
     8641 atacgcttaa taatgccctt tatcgctctt ccatatatta ttactactat tggcgcaact
     8701 aattatggga ttatcatttt ttctcaaaca attgtttcat atttttcaat tgttattaat
     8761 tggggattag atgtaacttc agtccgagaa gtgtctttaa atagaggtag tttaaaaaaa
     8821 atgagtttaa tcgtttctac tgtatttact attaaattta ttttgtttgg actttgcttt
     8881 tctattttca tgatatgttt gttttttatc cctttctttc aacaatatag aattatatat
     8941 ctgtatgctt ttttgtcatg cttttctgag gttattatac ctgtgtggtt ttttcaaggt
     9001 attgagaaga tgaagtattt gacttatata aggacaacaa gtatagttct ctatactata
     9061 cttgttttta cttttattaa aaaagaaatg gactttacac ttttagcctt attacaatct
     9121 ttggctaata ttactgcagg tgtattttca ttaatattat tattaatttt ttgtagagtc
     9181 aaatttgtat ttcctacttt cagagtgatg aaagaaactt tttgtaatag tacaccgttt
     9241 ttcgtttcca gagtttcgtt tttattgaat acgaatatag ctaaaacgat gagtgggtta
     9301 tttctgaata tgcacactgt tgccgcattt gatttgtctc agaaaatttt atcttttgtg
     9361 tctgttccca tacaaatgct gaatcaggcg atttatcctc atgttgcaaa aaatccaatt
     9421 aaatcatttt ctgtaaagat gctatatgtt atagctgcat tatctttgat tttatctgtt
     9481 ttactttttt ttctagcacc ctatatcatt ctttattttt cagtgcaact atatgctgaa
     9541 gctctaattt ttataaggat cttgtgtctt tatgtatttt gttttggtat taatacttat
     9601 ttagggactc cacttcttgt cgcttatggt ttttataagc catttaactt cagtgtaata
     9661 tattctactt tatttgtgtg ctctttgtac gggattttat acgtatttaa tttattgggt
     9721 ggggagtgct ttgctttagc aatgttctta acagagcttt ttattctgat atatagattt
     9781 tattattgtt tgaaatttaa attgatataa aaataatgga aaagatatct aactataata
     9841 ctgatggtac tatgttgcga aagcaacaag aacgtatgtt cgaaatgtta tgtgtaatag
     9901 atgatatttg tgtcaagaat gaaattaatt attggttatc tggtggaact cttttaggag
     9961 ctgttaggca tggaggtttt ataccatggg atgatgattt agatattcaa ctgatgaaag
    10021 atgactataa taaattacta ggtttattaa agacagaact tcctgaacaa taccagttac
    10081 aaacatctaa gactgataga aactatttcg caagatatgc gaaagtaaga gatgtgaatt
    10141 ctttgcttga agatagtgat tatactttgg gatataaata taaagggata tttatagata
    10201 ttttttctgt tgaaaaagca aataaatttc tagtaaagat atctgctttt atgcaatggt
    10261 atctattgat ctctttgtta cctatggtac ataagaaaac taaaatgcaa ttgaatcttt
    10321 tttcattatg gaataagttt ttaggtactt tttattctgg attcagacta tttggtaaat
    10381 tgtttgccaa gaaaattaat tattcttatg gagtttacta tcctttaaat tgtgattata
    10441 ctactatatt tccattaaca acaattgagt ttgaaggacg tatgtttaaa gttccaggaa
    10501 attataattt atatttatgt aatatatatg gtgattatat gaaacttcct ccagaggaag
    10561 aaagagaaaa tcataatata agagtggttc atattgttta gttctcacta tatttatgtt
    10621 aatagtaata ctactgactc taatcttaat atatatatta tataagatat ataaaaaaaa
    10681 gaaggttcat caatttttac tcatatattt tgctttttct gcttttttgt gggttatttt
    10741 tccatcgatt gtttctttaa taggagatag atataaacag gaattggtag taaaagaaaa
    10801 tgtttttata acttatgcta tttatgaatt tcttttttat ataatattgt tacttttact
    10861 ctatcgtttt ccattatgta aacctttcta ttatgggaaa tatattccca atacatcctc
    10921 gtctataaaa cgaatatggt ttgtattaag tctttttctc attattaata ttatcaagca
    10981 gatatcttcc aatgttactt attctgaagt caatgattca actatattgg ctgaacagga
    11041 aactaattta ttttcaattt tttcaaattt ctctatatgc ctatatctta ctataatatt
    11101 attttacaat aagctttatt caaaaagaat catttttttc tcttggctat tactatctct
    11161 taatataata acggttttag ctcatggagc aagaatgcaa gttatttttt atttgtttgt
    11221 ttttgtatat tatttatttt cttctgcatt aaataaaaaa cgttttttct tatatatgtc
    11281 ttttctgatc ggaattattt atttatgttc ttatattctt ccggcagttg catatataag
    11341 gtcaggagga aattttacag ttgaggattt gagaaagtca tatgagaatt atggggaagc
    11401 aaatgctttt gtccttcaat tgctgattaa gtctaatagt ataaatactg gggccatttt
    11461 agttgaggaa acaaaagaaa agccatactt gaatccatat attaattcaa tatattcatt
    11521 ctgcccaagt atactctttc ctggaaaaag acctttggca ggtagtagtg atggtacgat
    11581 tgatggattc cctacaagat tagccgcaga atatataagt ggtgattctc gtttctttaa
    11641 tgtgggaata tcaacttctg ccacggcact atggcatggt ggtattttat tttatgtgat
    11701 taatttaatt atagtttttt tttggtatcg ttttctgaat tcattaatgt tttatgaaaa
    11761 ctactatgca aaacttttag ttgtatattt tacagttttg gggtatttta tacttcctac
    11821 ggcagatgtc ttaatacggg atttgcttaa acagcccttc ttttatgcat tctttatatt
    11881 tatctcgaga ggtggtctta ttaaagattg ggttagatct ttgaaacgtc atattgctta
    11941 gtgaaaagat attctttgaa tttatcatca tgaataatcc catactttta tctattgtaa
    12001 tccctgtata taatgttgag ttatatattg aacgttgtct attaagttgt ttgaatcaag
    12061 atctttcaat atcacaatat gaaatcattt taatagatga tggaagccca gatagcagta
    12121 tcgataagat ttcaaaatgg ttagatagaa aaaatataac tttgttaact cagcctaata
    12181 gtggattaag cgttgcacga aataatggat tactacatgc aaaaggtaaa tatgtttggt
    12241 ttgttgattc cgatgactgg attttagaaa attgccttca agagattgca ggttatatgg
    12301 ttgctggaat tgatattatt actttctgtg ctgcagactt tattaatgat aaattttatc
    12361 ggagatttga atacataaca ggtgtaaata aaaaaatcga aggaagggat ttattaaaaa
    12421 gaggaacttg tcaacattgt gtgccatttt ctatatatcg gaaaagattt ttagaacaaa
    12481 atcatttgtt ctttttgcca aatatttttc atgaagatac agaattttct ccacgggcat
    12541 attatttagc gaatcatgtt ttttgtatta ataaggtatt ttattatgtg tatcataatc
    12601 ctaattcaat aacaagaaca tttaatccga aaaagtcttt tgatttatta attgtatctc
    12661 acagcttgtc tatattcatg ttggatgtta ctcctgagta taaatcttgt tttaataatt
    12721 tgatttcttt gtctataaat gctgcaataa atggcattgt tacggcaaaa agcgagattt
    12781 ctaggtttat agtggattta actgctagag gactgtatcg aaacatgctt aatgccggaa
    12841 aattaaggta taaaatggaa ggattactac tctatttatg tccggcattg ttgatttgtc
    12901 tgtataaaca ttactcttca ttgagaagaa ttattaaata atctaataaa aatgttatgg
    12961 tgtttgttaa accaattaag attgccgtaa taggtcttgg ttatgttggg ctacctttgg
    13021 cccgattgtt ttcgacaaaa tatgaatgta ttggttttga tctgaaccag tctcgtgttg
    13081 atgctttaaa ttccggtcat gatatgactt tagaggtttc tgatgactta cttcggaaag
    13141 cgttagaaaa tggtttcaaa tgtaccagta atattgacga aataagtaat tgtaactttt
    13201 atgttgtagc tgtaccaacc cctgtggatt tgaataatcg ccccgatctt acacctttga
    13261 ttggtgcgag tacaacagtc ggaaaagtta tttcaaaagg ggatattgtt gtgtatgaat
    13321 ctactgtata tccgggagta acagaggaag aatgtcttcc ggtagtcgaa gaggtgtctg
    13381 ggttaacata caatgtagat ttttatgcag gttattcacc agaacgtata aacccgggtg
    13441 ataaagagca tactgttgaa aagattaaga aagtaacttc cggttcgact cctgagattg
    13501 ctgacattgt tgattctgtt tataattcag tgttggttaa cggtactcat aaagcccctt
//
