LOCUS       gnlProkkaFMNHHJJD_42   13075 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FMNHHJJD_42.
ACCESSION   gnlProkkaFMNHHJJD_42
VERSION     gnlProkkaFMNHHJJD_42
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 07:28:29
            Original ID  :: gnl|Prokka|FMNHHJJD_42
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13075
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13075
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[3761:8075]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3762..8075
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..13075
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13075
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             128..2539
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 32.3;
                     E-value: 7e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg42_1"
                     /sec_met_domain="Poly_export (E-value: 1.7e-18, bitscore:
                     56.9, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIQRLFSILLFCLMLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQ
                     KQLASELARKGVTKEQAMRVKQLYEQQNNVNTSKSTGTDINESRLREETKKNTSDMLED
                     HPTTQDLARGDQVFGRNIFNTRNLTFEPSVNLATPANYRLGPGDEVIIDIWGASQNTIR
                     QQISPEGTINIQKIGPVNLSGMTVSAANDYLKNALNKIYNGLNNTTDPTSDIRLTLGNI
                     RTIQINVMGEVVQPGTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVY
                     EFIMKGNTQDDIRLQEGDVVIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGGF
                     EADAYTRSLRVGRQNGEEYEVNTVKDIDYNIYKMRNGDVVTAEAILNRFTNKLEIRGAV
                     YRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGT
                     SPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEA
                     ASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSPG
                     YQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKK
                     RMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIP
                     KNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKG
                     SGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             2550..3698
                     /locus_tag="ctg42_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVNKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             3762..4481
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.5e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             4502..5803
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_4"
                     /sec_met_domain="CTP_transf_like (E-value: 3.1e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 3.2e-121, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 3.6e-63, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             5820..6944
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.7e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             6954..8075
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg42_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_6"
                     /sec_met_domain="Aminotran_5 (E-value: 2.4e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        7044..8051
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg42_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg42_6_Aminotran_5.1"
                     /locus_tag="ctg42_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             8072..8215
                     /locus_tag="ctg42_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             8418..9902
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_8"
                     /sec_met_domain="Polysacc_synt (E-value: 2.1e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             9856..11115
                     /locus_tag="ctg42_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             11124..11873
                     /locus_tag="ctg42_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             11873..12913
                     /locus_tag="ctg42_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 ctgttttgac ccgttctctg tctcttctcg atgttcttcc cccttctctt cttaagcaac
       61 agttatctgc cgtctgtcat gggatgcagg aactgtgtga aatcaactga aactttttta
      121 tttgtcaatg aaaatacaac gactttttag cattctacta ttttgtttga tgctgggaag
      181 tggctcgctt atggctcagt ccatgagtga ctcacaggta ctggaatatg taaaagacgg
      241 catccgccaa ggcaaggaac agaagcagct tgcttccgaa ctagcccgta agggtgtaac
      301 caaagaacag gcaatgcgtg tgaagcagct atacgagcag cagaacaatg taaatacctc
      361 gaaatcaacg ggcacggaca tcaacgaatc ccgcctgcgt gaagagacta agaagaatac
      421 ttccgatatg ctggaggatc atccgactac tcaggacctt gcccgtggtg atcaggtctt
      481 cggacgtaac atcttcaata cccgcaacct gacgttcgag cctagtgtca accttgccac
      541 tcctgccaat taccgtcttg gtcccggtga tgaagtcatc attgatatct ggggtgcgag
      601 ccagaacacg atccgccagc aaatctctcc tgaaggtact atcaacattc agaagatcgg
      661 ccctgtcaac cttagcggta tgacagtctc tgccgccaat gactatctga agaacgccct
      721 gaataaaata tataacggtc tgaataatac taccgatcct acttccgaca tccgtctgac
      781 gttaggtaat atccgtacta ttcagattaa tgtgatggga gaagtcgtac agcccggtac
      841 ctacgccctt tcttccttct ctaccgtctt ccatgcgctt tatcgtgcag gcggtgtgag
      901 tgatatcggt agcctccgaa acgttcagtt ggtacgcaac ggaaagaata tcgccaccat
      961 cgatgtttac gaatttatca tgaaaggcaa cacgcaggat gacatccgcc ttcaggaagg
     1021 tgacgtggtt atcgtccccg cctacgatgt cttggtaaag atcagcggca aggtaaaacg
     1081 ccctatgcgt ttcgaaatga agaaagacga gaaccttgcc actttaatca aatatgccgg
     1141 cggctttgaa gctgatgcct acacccgttc attacgtgtt ggccgtcaga atggtgagga
     1201 atacgaagtc aacacagtca aagatataga ttacaacatt tataaaatgc gtaacggtga
     1261 cgtagtaacc gccgaagcca tccttaaccg cttcacaaac aaactggaaa tccgtggcgc
     1321 tgtctatcgt cccggtatct accagctcag cggtaaactg aacacgatcc gcgaacttgt
     1381 ccatgaagct cagggtctga ccggtgacgc tttcctgaat cgtgccgtcc tctatcgcca
     1441 gcgtgaagac ctgaccagtg aagttgttca gatagacatt aagtctatca tggacggcac
     1501 ttccccaaac cttgccctaa tgaagaatga catcctctac attccaagta tccatgacct
     1561 ggaagaccgg ggtaatgtca cagttcacgg tgaggttgcc caccctgatt cctatcctta
     1621 tgcggataac atgacacttg aggatctgat cattcaggcc ggtggcttga aagaagccgc
     1681 ctctactgtc cgtattgata tatcgagacg aatcaagaat cctcgtagta ctgcggataa
     1741 tgatacgatt ggtcagatgt ataccttctc tttaaaggat ggttttgtaa tagatggtca
     1801 gcccggtttt atccttgagc cttatgatca ggtttatgtc cgtcgcagtc cgggctatca
     1861 ggcacaacag aatgtagcca ttgaaggtga aatccttttc ggaggaaatt acgccatgac
     1921 cagccgtgag gaacgtcttt ccgatttagt gaataaagcc ggcggtccga ccaattatgc
     1981 ctatctgcgt ggtgcgaaac tgacccgtgt ggctaacgct agtgaaaaga aacgtatggg
     2041 tgatgtaatt cgccttatga gcaggcaatt gggcgaagcc atgattgact ctttgggtat
     2101 tcgtgttgaa gatactttta cggttggaat agatttggaa aaagccttga gcaatcctaa
     2161 aagtaatgcc gatcttgtct tacgtgaagg tgatgtgatc tccataccta agaatactaa
     2221 tactgtaact atcaatggtg ctgtcatggt tccgaatacg gtttcttata tgaagggaaa
     2281 gaatgtggat tattacctga atcaggccgg tggctgttct gataatgcaa ggaagagtaa
     2341 gaagttcatt gtttacatga atggtcaggt gacgaaggtt aagggtagtg gtaagaaaca
     2401 gattgagccg gggtgtgaga ttattgtgcc tggtaaggct aagaagaaag ggaacatagc
     2461 taatatttta ggttatgcta cttccttcag ttctttggga atgatgattg cttctattgc
     2521 taatttgata aagaaataaa tgacctatta tgattgaaaa gcaatcttat caagaaccgt
     2581 tttctgaagt gaataaaagg aaagatgatg aaatggaaat agacttgatg gctatttttt
     2641 ataagattat tactgttcgt ggagtactat gcaaagctgc tggagtggga gtaataattg
     2701 ctatagtggt ggcattgagc attcccaagc aatatacagt aaaggttacc ctttctcctg
     2761 aaatgggtaa tgcgaaggga agtaatggtt tagccggact tgctgcctcg tttttgggag
     2821 atggggctct aataggggaa agcacagatg ccttgaacgc ttctctttca gcagatattg
     2881 tttcttcaac tcctttttta ttggaacttt tagaaatgga agtctccgtt tctaaaaagg
     2941 atgataaaat gactttgggg tcttatctcg atgaagagtc atctccttgg tgggattatc
     3001 ttataggttt tccgggcata gtaataggag gagttaaatc attattcgga gaagatacgg
     3061 ttcctgccag tggagggcgg caaggaacta tcgaattgac gaaagaagta aatgagaaga
     3121 ttaattttct taaaaagaag attagtgcat ccattgataa gaaaaccgcc ataacgagca
     3181 ttacggtcac cttacaaaat ccgcagatca ctgcggttat agcagattct gtcgttcata
     3241 aattacagga atatattatt gggtatcgaa cttcaaaagt aaaagaagac tgtgcgtatt
     3301 tggaacggtt gtttaaagaa cgtcagcagg aatattatgc tgctcaaaga aaatatgcgg
     3361 attatgtaga cgcccatgat aatgtggttc ttcaaagtgt acgtgctgag caggagcgtt
     3421 tacagaacga catgagtttg gcttatcaga tatatagtca ggttgctaat cagttgcagg
     3481 tatccagagc caaagtacag gaggaaaagc cagtctttgc agtagttgag cctgccgttg
     3541 tacctttgaa accttcaggt atgggactca aaatttatat tttattattt gtgttcctgt
     3601 ccgtatctgg tactctcgtg tgggtgtttt ttggcaaaag tctgctggct agcttgagaa
     3661 aagaactgaa aaataaggag atagaacagg ataaatgatg ctaaaacgtc gtttacaaca
     3721 ttcttacatc aattaaattc acttactata ttattaaacg aatgatacgt acagctatga
     3781 taatggctgc gggcatggga acccgttttg gccaatatac agaattgata cctaaagggt
     3841 tcgtcaaagt gggaggtatt ccaatgatag ttcgttctat tgatactttg ttatcatgtg
     3901 acattgagcg aattgtaatc ggtacaggat ataaacaaga agtttatgaa gaattgaaga
     3961 cagactatcc tatgcttgaa acctgtttta gtcctcgtta tgctgaaaca aatagtatgt
     4021 atactttata taatacgcgg gagattctgg gcaatgatga ttttttattg ttagagtcag
     4081 atttgatttt tgagaaacaa gcaataatga gcttattgga gtgtcctgcg gcagatgcaa
     4141 tgctaataac tccagtgaca aagtttcaag atcagtatta tgtggaacat gatgataatt
     4201 ttcgcctttc ttcatgttct gtcaataaga ataaactaaa cgctaaaggc gaattggtcg
     4261 gcatccataa actatccggt tccttttaca aaataatgtg tgctgattat gcgagtattg
     4321 ttgatgaaca acccaatttg ggatatgagt atgaattact acgaatatct tgttctcaat
     4381 ctcctgttta tgtgcataaa gtagaagggc tgaaatggta tgaaatcgat gacatatcag
     4441 atttggaata tgcagagaaa tatattgttc cgtattgtta attaaaataa tatatcaaat
     4501 tatgagtaag acagtttata ttgggatgac tgcggatatt atgcatccag gacttatccg
     4561 cattattaat gaggctacta aatacggtga tgttataatt ggtcttctta cagataaagc
     4621 tattgcggag cataaacgcc ttccttatct gacctatgaa caacgaaaag aggtagttca
     4681 gaatattaaa ggcgtatgta aagttgttcc tcaagaagaa tggagctatg ttgagaatct
     4741 caaacgcatt aaacctgact atataattca tggtgacgac tggaaaaccg ggcctttacg
     4801 tgaagaacgt gtgcgcgtat ttgaagtgat gaatgaacag ggaggaaagg ttatcgaaat
     4861 tccatatact ttgggaatta attcatcttc tttggataaa gatattaagg ctataggtac
     4921 aacccctgat gtacgtttaa aatcacttcg tcgtttgata aatgccaaac ccgtagttcg
     4981 tattttggaa gctcatgatg gactatgtgg cttgataatt gaaaatcagg aaatattaaa
     5041 aggggataag agggaagtat ttgacggaat gtggtctagt agccttacgg attcaaccag
     5101 taaaggtaaa cctgatattg aggcggttga tttaactacc cgattgcaag atttgaataa
     5161 tattctggag tgtactacta aacctattat ttttgatgga gatacaggtg gtaaaattga
     5221 acatttcgta tttacagtac gcactttaga acgtcatgga atttcagcta taataattga
     5281 agataaagtt ggattaaaaa agaattcatt gtttggtaca gatgttattc aaactcaaga
     5341 tacaatcgaa ggtttctgta ataagatcaa agcaggaaag gcatctcaga ttactgatga
     5401 ttttatgatt atcgctcgta ttgagagcct tatagcggga aagccggtaa gtgatgcttt
     5461 agagagagct tttgcatatg tccaagcggg agcggacggt attatgatac atagcaaaaa
     5521 taagtcgggt gaagatataa aagaattttg tttggcgttt cgaaaacagt atgctcatgt
     5581 acctatcgtg gttgtgccta ctacatatga tcatatttat gagtctgaat tgtgtgattg
     5641 gggtgtgaat ataattattt atgctaatca tatgcttcgt gccgcttatc ctgctatgat
     5701 gaatgtcgca aagataatat tagagaatga acgtgcttta gaggtgcgcg aactgtgtat
     5761 gcccataaaa gaaatattgg aactgattcc aggtactaaa taaaaagagg aatatcatta
     5821 tgttaagcgt agaaaaagtt tatgaaacgt ttctgagtca tgacgttgat ttttttacag
     5881 gagttccaga ctcattacta aaaaatattt gtgcctatat cacagaccat acttcacgtg
     5941 agaaacatat catagctgct aatgaaggtg cggctgtagg aattgcttca ggttattata
     6001 tggcatcagg taaggttcct gtggtttata tgcaaaattc cggcttgggt aatactgtta
     6061 atcctctgct gtctcttgca gatgaacaag tatacagttt tccaatgctt ttgatgattg
     6121 gctggcgtgg tgaaccggga acaaaagatg aacctcagca taaaaaacag ggtgaggtaa
     6181 ctttagattt gttgaaagca atgcggattc cttatataat tcttgattca aatgagaatg
     6241 atgcatttat tcagctccat gatatcatac aatcagcaaa aactaagaat attcctcatg
     6301 caataattat tcggaaagat gtttttggca aatataaact tcaaaaagag ttcggatgta
     6361 attatccttt atctcgtgag gatgctttgc aaatagttgt ggattatctg cctgaaaatt
     6421 cagtggtcgt ttctactact ggcaagcttt ctcgtgagtt atttgaatat cgagaaatga
     6481 aagagcaagg tcatgaacat gattttctca cggtaggctc tatgggacat agttcatcaa
     6541 tctctttggg tattgctata gcaaagcaag atagacctgt ttattgcttg gatggtgatg
     6601 gagcatttat tatgcattta ggggcaatta gtaacattgg cgatttatct cctaaaaact
     6661 attatcatat tttgtttaac aatggtgctc acgagtctgt aggaggacag cctactttag
     6721 gatttagttt agatattccg gctattgtcc gggggagcgg atataagcat acttatactg
     6781 tttgtacaaa agttgaaatt gaagaagcaa tgaagcagct tccaaagtta tgtggtcctg
     6841 ttttgttgga aataaaggtt aaaatagatt ctcgggagaa tttgggacgt cccacgacta
     6901 ctcctataga gaataaggag cattttatgg attttttaaa ataaatatat tcgatgaaaa
     6961 tagaaagaaa aatattatta aatcctgggc ctgccactac tactgacagt gtaaaaatgg
     7021 cacaagttgt tccggatatt tgtcctcgcg agaaagaatt cgcaggtatg atgaaacaac
     7081 ttcgggacga tttggtcaga gttgctcatg ggaatttgga aaaacatacc gctgtattat
     7141 tttgtggctc aggaaccatc aatattgata tatgtctaaa ttctcttctt cctgaagaca
     7201 aaagggtgct tatagtgaat aatggggcat atagtacccg tgctgtagaa gtgtgtcaat
     7261 attatggttt gcctcatatt aatttggaat tttccgttta cgaacgtcct gatttatcgg
     7321 tggtggaaaa tgtgttgcaa gaaaatcctg atatagctat ggtttatact actcatcacg
     7381 agacgggtac aggaattctg aaccctattc gcgagatggg cgctatagct cataaatatc
     7441 aggctaaatt tgtcgtcgat actacttctt ctttgggcat gattcctttt gatatagaga
     7501 aagataatgt ggatttttgt atggcatctg ctcaaaaagg acttcaagcg atgacaggtc
     7561 tttcttttat tataggcaat gaggaacaga ttaagttttc aaaaaaatat cccaagcgtt
     7621 cttactattg taatctttat ttgcagtatg agaattttga gagaacaggt gaaatgcatt
     7681 ttactccacc ggtacaaact atttacgcca ctcgtcaggc attaaatgaa tattttgaag
     7741 tgggtgaaga agctaagttt gcccgtcaca aaagagtttt tgaggctatt cattcaggta
     7801 taaatgaaat tggtcttaaa agtgtaataa agcgtgaatg gcagtcagga ctggttgtct
     7861 cagttcaata cccagaagat cccaactggg attttgagaa aatacatgat tattgttatg
     7921 agcgtggatt tacgatttat ccaggtaaga tatcaactga ggatactttt agaatctgtg
     7981 ctttaggaga gatagaagta gatgatattg agaacttctt taaagtacta aaagctgcat
     8041 taaatcatta taacgtcaca ttaccgatgt catgattgca gaaatattat tgaagattcg
     8101 tcatttttat ttttcccttc gtggtataca cttccatccg gaaagtgtta tttctggagt
     8161 gcctattcgt agctttcgct tagtaggcaa atatggcaat attaatttga ggtgatgcat
     8221 taggagttct ttattcttat aaaaaggcat cggtagttat aggagataat gtttgtgtag
     8281 ggtaatttgc ttttagtggg agagaccata ttagaattgc ggtaaggggc gaagaagata
     8341 ataaccaatt agtgagaata ttggaaaaat ataattgata tcggtaaatg tagttgtttt
     8401 tatactgtat ttaagtaatg gaaaatctaa agcagaaaac tgtatcagga ataatgtgga
     8461 gcgctataga acgtttctct ttacaaggag tacagtttat aattcaaata atattagctc
     8521 gtttgttact accatcggat tatggtatga tcgggatgtt agctattttt cttcaagtcg
     8581 ctcaagtatt tatagatagc ggttttacaa atgctttaat ccagaaaaaa gatagaactg
     8641 aagaggattt tgccactgtc ttttatttta atattcttgt cgcagtatta ttctatggta
     8701 tattgttttt ttcggcttct ttgattgcag acttttataa tatgccgact ttagttcttg
     8761 taattcgttt tatagcattg tcgttgataa taaatgcttt atcggctatt cacagaacga
     8821 aattaattat ttctgtaaac tttaaaactc aatctaaaat ttcattaggt gcagctttta
     8881 tatcaggcgt gattggaata tggatggctt atgtcggttg cggggtttgg gctttagttt
     8941 ggcaaactct cttaaatagt ataattttga caattttgtt ttactgttta gttcattgga
     9001 aacctttaca tactttctcc aaaagttctt ttgaaagatt attcaatttc ggatctaaat
     9061 tattgatctc aagtcttatc aatacagtat atcgtaatct gtataccatt gtaataggaa
     9121 aaaagttttc tgttgtagag cttggttact atacaagagc agaacaattt gctatttttc
     9181 cttccaataa tttaaatgct ttagtttcta gagtagcgta tcctatttta agttccattc
     9241 aagatgatga taaatgttta acaaacgcat atcgaaatta tatcagatta tcctcatata
     9301 taatttttcc tttaatggta ggtttacttg ttttggctaa tcctattatt agtctattgt
     9361 taacagataa atggtctggg gttgttattc ttttacagat attatgtttg gattggatgt
     9421 ttgatcattt gagccaaatt aatttgaatt tattatgggt taaaggaaga tctgatctgt
     9481 cgttacgtct tgaaataata aaaaagacga ttgctatatt cattcttttt gtgtcaattc
     9541 catttgggct tgaggtgatg tgttggggta gagttattta ctctctgata gcgacatatt
     9601 tgaatacata ttatactaat tctcttattg atttgacctt aaagttgcaa gttaaagatg
     9661 tatttccaag tttaatactc tctttcataa tgggggggat cgtttttata tgtatttctt
     9721 tctttgaaac tgatatagta aaaattgtga ttggatgtat tactgggatg tccttctata
     9781 ttttactttc ttttcttttt aagctagatt cttttttttg tattttaaca ttgatcatta
     9841 aaactaaaaa catagatgaa aatattaaaa aagatttttc aagtaatagt aaagataatt
     9901 aaccattgtg tgccagttga tagtagatca ttgtatttta ttcctcatcc taattgtaga
     9961 acagataaat atgatattat aaattattcg tcagataatg ttctcgttct gttaaattat
    10021 ttgctaaaaa aagatagtgc tgaatattat aaaatatatg ttgaaattta tgattcttct
    10081 cgtatttcag aatatcaaga atatatttat ggcataaatc ctaatattag gtgtactttt
    10141 ttatgtgcat gtgttggacg ttttttcttt aataaagtat cttttaagga tatgttgtat
    10201 gccttttttt gtttttgtag agcaagtaaa tgttttacag ctacttttta ttatgatttt
    10261 tcatttaaaa aacgctctca acagattatt tgtttggggt attatactcc attcaaagat
    10321 gattatcata tgggagatca ttcttatgat aaatttcgta atacaacatg taactcattt
    10381 gattactcta ttgctacttc ttgtttaagt gctagaataa tttcaataga ttgtggaatc
    10441 tcatatgata aattcaaagt cttaggattt cccagaaatg atttgttgat atcgaaaaat
    10501 aattgcaatg ttattaaaag agaaatttcg aaatttgcgg gatatgatgt aactaaatat
    10561 atagtttata ctccaacttt tcgtgattat gagactgtta ctgaaggtaa tttgcgttca
    10621 atactcggat atgttgattg tgatttgttg aagttatcga aaatactatt gaagtttaat
    10681 gcggctttaa ttcttaaatt acatcctttg cagaataaaa cagtcttaaa aaaagattta
    10741 cccaaaggta tacttgtttt tgaacaaaca tataaatatg gattgtatga tcttttgtca
    10801 ttttcagatg gaatgattac tgattatact tctacctatt ttgatttttt attggtaaat
    10861 aagccagtca tatttaattt ctacgatatt gaagaatatc gtagagtaag aggtttctca
    10921 tttgagccaa tagaattttt ttgtgcaggt gatattgttt acaattataa tgaattgata
    10981 gatgctgtga tgggacttct ggctgggaaa gatattcatg ctgaacatcg acgtcatatt
    11041 tctttattga tgaatcaatt tcaagatgat aattcaacaa agagaatatg tgacatattt
    11101 ttaaatgaaa tataataaat aaaatgaatt atgcatttgt ggtgcaggca cgtttaggtt
    11161 ctacacgttt gcctggaaaa atattgaaac ctttctatgg taatcaatcg attcttgact
    11221 taatggttca taagctttct gctatatcga atattccagt aattattgct acaacaaatt
    11281 ctgttatcaa tgaacctatt gaaaagaagg cacttgcatt aggggtaaag tgcttcagag
    11341 gtgaggagaa tgatgtttta aaacgattca ttgatgttgc tgaatatttt gatatacagg
    11401 gtatattccg aatatgttct gataatccat ttttagatgt acatgcggca aggcaattgg
    11461 tcgaaatagc aatgaaatct tgtaacgatt atataagttt tgatattgat ggtactccat
    11521 caattaaaac tcatttcggt ttttggggag aatttgtaac gcttgatgcg ctgaagcgag
    11581 ttataggatt tactgatgat ttattgtatc gtgaacatgt tactaattat atatatagtc
    11641 atcctgaact ttttaatatt caatggattt caggatctcc agtcgtgtca aaacatcata
    11701 atattcgact cacgattgat acgttagaag atttttctgt agcacagaga atatataggg
    11761 atttacaaga aaaaagagtg gaaatatcga tagaagtgat tgtagactat gttcgaagac
    11821 atgcagaata cattcaactg atgaaacaac aaataaaaaa aaattctaaa taatgaagaa
    11881 tacttatatt attggtgaaa tagggcagaa tcataatggt tctgttgact tggctaagtt
    11941 gattattgaa ttaatctcac gacctgtaca tgaggatgtt tttggtatgg atttcatgcc
    12001 aatgaatgct gttaaaatga ctaaaagaga tttatcagaa gaattggctg tttctcaaat
    12061 gaatcaaata tatgacaatc ctaattcttt tgggcgtact tatggtgaac atcgtgcttt
    12121 tcttgagctt gatgatcaag cgcattttga gatttataaa tatgctaagt cattaggatt
    12181 agattttatc gagacgttat gtgccaaagg atgtctgtct ttgcttaaac tgttcacacc
    12241 ggataggcta aaagttgcta gtcgtgattt gactaactta ccattgcttg aagcattagc
    12301 agaaactcat attcctatta tattatcgac aggaatggct ggtcaaagag aacttgacaa
    12361 tgcattagat gtgataacga gatatcatag taatatagct attctacatt gtgtatctca
    12421 gtatccaact catccaaata atttgaatct acgtacaata acatatttga agaagcatta
    12481 caataagttt gagataggtt tttctgatca tacaataggt atttctgctg ctacagctgc
    12541 tgtagcgatg ggagcggaaa ttatagaaaa gcatgtaaca attgatcggc atatgaaagg
    12601 aacagaccag cttggctctt taggtccaga tggggttaat cgtatgattc gagatattcg
    12661 catagcagag tgttggcttg gtactgaaga tctttatata gaaaaagggg tggagaagtc
    12721 taagataaaa cttgaacgtt ctattgccac tcgaaaatat attccagcag gtagtattat
    12781 tcaagagtcg gacattcatt tactgagtcc tggtgatggt tataaatgga tagataaaaa
    12841 aaatgtaatt ggtcattttg ctaaacaaga tatatcagcg aatgaaataa tatatcctga
    12901 ttttattgaa tagatatatt cctactgcaa cttgtattac ggtatagagt actgcctgct
    12961 ataagctaag tagtgattaa taaataaggg taaaatacta aaaaaatgaa agagataaag
    13021 cttatactta cagatattga tggcgtttgg actgatggcg gaatgtttta tgatc
//
