LOCUS       c00033_gnlPro..        16334 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LHPPGPCB_49.
ACCESSION   c00033_gnlPro..
VERSION     c00033_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 08:11:16
            Original ID  :: gnl|Prokka|LHPPGPCB_49
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 31588
            Orig. end    :: 47922
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16334
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[41588:45140](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..13552)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16334
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16334
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             1916..4756
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 62.8; E-value: 1.2e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_18"
                     /sec_met_domain="Peripla_BP_1 (E-value: 4.9e-20, bitscore:
                     62.8, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAMKYMKWITVLFCLLGLAACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDKGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNYPDIKLIDKADAAWEREPAEVEMDSMLRRHPKIDAVYAHNDRI
                     APGAYQAAKKAGREKEMIFVGIDALPGKGNGLELVLDNVLDATFIYPTNGDKVMQLAMN
                     ILEKKSYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRSKNRLNKELSEQKKQVEQQRDKLEEQRDQLIQLSH
                     QLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADSSLSEDQRRMLLLVQRNVNILL
                     RLVNQILDFRKYENGKMEYTPISLDILSSFEGWNESFMAAARKKHIHFSFDYMPDTDYR
                     TLADVEKLERIYFNLLSNAFKFTPENGKVTVRLSSLTKDDHCWIRFTVANTGSMISAEH
                     IRNIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTITVESDEKQGTIFTVDLPVQTCET
                     VVSENSPAFSVPATSVTSTDAATSAVAGAPVTPATSGYSGSSSLNDALTYEEEELEKSY
                     DSSKPCVLIIDDNADIRLYVHGLLHTDYTVIEAAYGSEGIRKAMKYVPDLIISDVMMPG
                     MDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYISKPFSSQLLLARVR
                     NLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGDSNLNVEDLGKDMGL
                     SRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGYEVGFSSPSYFTKCY
                     REQFGESPTDLLKRKG"
     CDS             complement(4898..6193)
                     /locus_tag="ctg33_19"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPIKSNPIINKTSTAVMKKKTILFASCLLGA
                     LAFSSCEKNLYDESKQPEKEKKMTDLEVPADFDWKGSQNAKVKIASQSTATISVFLEEN
                     CNEEALMLRMDVDANTSKLELPIEIPAYIKNVYVKYGNGSEIQTVPVESNGTISIVVPA
                     NATALSRVTTRANKEVETNNIFNYPGYGNGTIMFEDMYPALGDYDFNDFVAWYNFQIDG
                     FYWSHNQCYAEYLMIGFQIRAIGGIYDYNLYIRLAEVQYNELDLEETQMYLERNNPEEA
                     ENIKILKGPKGELIISLKKPAIPNGYKYYNTEVNEKTKPKKMMAIYLVFNSPVNVKSLQ
                     DSKMDFYIAKTNKGQEIHLKGYSPVYYNSNESYVNEDNFIWGLKVPASLHHAREEVNFL
                     EAYPDFEQWVTSGGQENQRWWNKPKTNKLIMN"
     CDS             6277..6615
                     /locus_tag="ctg33_20"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMSQ
                     CSRMVGRALKQIPDDLSAPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVPE"
     CDS             6914..8140
                     /locus_tag="ctg33_21"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTTGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSKQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETREFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             8137..8961
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.9; E-value: 6.9e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg33_22"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     92.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMIHFSTFFDAVNAGIGSFIIGFQHILFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSSRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             8982..9848
                     /locus_tag="ctg33_23"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAMLLLASCTNSDLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFLG
                     EVYGEARVGLVVPQYVTIQSISELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWMVITGWTPHWMFDLFYLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRLLVDSW
                     IPKSENK"
     CDS             complement(10001..13552)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_24"
                     /sec_met_domain="PFOR_II (E-value: 1.4e-18, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.7e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.7e-31, bitscore: 100.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.7e-12, bitscore:
                     38.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 5.8e-12, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 9.2e-09, bitscore: 26.0,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.6e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 2.8e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNPENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKVFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKTKQHLVDIKSNVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNQILEGDNAPAEAKEVLKAWIENMYDADKTKE
                     LAPQIEAIIEQGIAAGCPVSKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPTEAEELFKAAEENAK
                     WRYNSYKRLARENWGAE"
     CDS             complement(13585..14763)
                     /locus_tag="ctg33_25"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     RELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREYLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNLNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             14998..16125
                     /locus_tag="ctg33_26"
                     /transl_table=11
                     /translation="MAPASARQMASELALLPMWYAEEGSVVLAPSAYNLDYVKKIQELL
                     GLSVDLMTEPELASERNLDIRPWGWDIAIRKRLLDLGVEESELPSIEQLDKLRFCSHRS
                     CAVGLLPQLQLGACFCGESFYLTFPEEWKSFVESHDTCLLKAPLSGSGKGLNWCKGVYT
                     PSISGWCSRIGNQQGGVIGEPLYNKVEDFAMEFRSSGNGRFGFAGYSQFRTGGSGAYEG
                     NLLISDAAIERNLSEYIPVEEIYKLRDRLEQELSLRFGTIYNGYLGVDMMICRFPESPV
                     YRIHPCVEINLRMNMGVVARHIYDHYIYPTSTGAFQISYYPTEGTAWRAHKEMEEAYPL
                     EIEQGRIKSGYLSLVPAHKKSSYRAWVFISKSVFL"
ORIGIN
        1 gtacagtttg aaacaacttt ccccgataat gtgacgaaat gggaaactgt cgtttatggc
       61 atgaaccgtc gtttgcagac gggtactttc cgacgttcca tccgctctta caaaccgttg
      121 atggcggagt tgaaaactcc ccgcttcctg gtggaggggg atcagagtac ggtggttggg
      181 actatccgca attatctgga tgggcagcac atagccggaa agacacagtt ctgcgtcgga
      241 acggatacgt tgaaacggca ggaagtgagt ttcatggagg gatttcatga aacagtgccg
      301 atgcaggcag ttcatgccga tagcgtgacc atcagctatc ttttcactcg cgacgatggc
      361 tatcaggatg gagaggaata tacgattccg atactgccac agggaactga attggcggag
      421 ggcacattgg gtattctgtc cgatgcaaag acggtcaaag tgcaatccgg cgaggatgaa
      481 gaagtgatgg tgagtatcac tgacaatcag ttggacatct ataaagaatc agtgaattac
      541 ttgacaggat acaaatattt gtgcaatgag cagctggcat ccaagttaat cggtttgttg
      601 gcttaccaac agtatatgca gagtaagggt gaaaaggtga aagtagataa agcaattcga
      661 cctatcatcc atcgactgac gaatcatcag aacaaacatc agttatggtc gtggtggggg
      721 aactctgaaa atacttcttt ctggatgtct gcgcatattc tgcgggcttt gaagatggcg
      781 caagatgcag gttatcctgt ggagttgaat ctgaatggtt tgaaagtgga gtatgctcat
      841 atgcgtcctt atcgaggaat gaaactggaa gatatagaaa tacttcatgc tctgcatgag
      901 tggaaagtag aggcggatta ttcttcggca gtcagattat tggaaccttt cgtccggcaa
      961 ttggaacaga aagaagactc gttggcaaat agaaacaagt attatcgtcc tctttcatac
     1021 ttgaaagaga agctgcttct ctgggaaatc aagcaacagg tggattcggt gaatgtgggt
     1081 gatagcgtac gtccttatct gaaaaaggat atgctggaag gtgtttactg tgacgacgga
     1141 cggcgtactt attattggga gggaaatcag atgataaata cattgatagc ctaccggatt
     1201 attaaaaatg acccttccct gtgtaagttg aaagaaaata tgcaattgta tattttgcgg
     1261 actaaggagc gcggatggaa tacgtatcag gcttcttcgg ctgtggcaac tgttctgacc
     1321 gatttgctgg caggttccgg agggatgtca ggaacgtcgg tgtctgtgag cggtaaggat
     1381 catcaacgaa ttacggaatt tccttatcat gcccggctga tagcaggcga cagtctgctt
     1441 atttcaaaaa cgggaaaaga gcctttattg tatagtgtct attcaatgaa gcgtgtgatg
     1501 aatgctcgtc agagtgatgc tttcaaggtg gaggcgactt tggaaaaaga ctctttggtg
     1561 gcgggtgtac ctgttacatt gacagttacc ttgcaggtga aacaggaggg tgcgcaatat
     1621 gtgatgctcg aagttcctgt tccggcaggt tgtagttatg cctcaaaacc tgttaatttc
     1681 tcccgttctg aagtatatcg tgagtatttt aaagagaaaa ctgttatctt tagcgaaaaa
     1741 ttaccggtag gtacttatca gtttacggtt cctttgcttt cacgctttac tggaaaatac
     1801 acgctgaacc ctgtgaaagt ggaactgatg tatttcccgg tggtgaatgc aaataatgcg
     1861 gggagagaaa tttggattac agaaagaaat acaaaagata tacgaaagaa agggaatgat
     1921 tgaagcgatg aaatatatga agtggataac agtcttgttt tgtcttttgg gcttggcggc
     1981 ctgtcgtcag gatgcgcctc gtttccgtat tggggtggcc caatgtagtg atgactcttg
     2041 gcggcacaag atgaatgatg agattcttcg cgaagcgatg ttttatgatg gagtgtcggt
     2101 tgaaatccgc tcggcggcgg atgataaccg taagcaggcg gaagatgttc attattttat
     2161 agataaagga gttgatttac tgataatttc cgccaatgaa gcggctccca tgactccaat
     2221 tgtggaggag gcctatcaga aaggaatacc tgtcattctt gtagaccgga agatactttc
     2281 tgataaatat actgcctata tcggtgccga taattatgaa ataggtcgtg cggtaggaaa
     2341 ttatatcgca tcaagtctga aagggaaagg gaatgtagtg gagcttaccg gactgggtgg
     2401 ttccacccct gccatggaac gccatcaggg atttatggct gctatcagca attatccgga
     2461 tatcaaactg attgataaag cggatgctgc ctgggaacgt gaaccggcag aagtggaaat
     2521 ggatagtatg cttcgccgtc atccgaagat tgatgcggta tatgcacata acgaccgtat
     2581 cgctccggga gcctatcaag ctgcgaagaa agccggacgt gaaaaggaaa tgatttttgt
     2641 tggcattgat gccctgcccg gcaaaggaaa cgggcttgaa ttggtgcttg acaatgtgct
     2701 ggatgcaact tttatttatc cgactaatgg ggacaaagtg atgcaactgg ccatgaatat
     2761 tcttgagaag aagtcttatc ctcgcgaaac ggtcatgaat actgccgttg tagaccgcac
     2821 gaacgcgcac gttatgcaac ttcagactac ccatatctcg gaactggatc agaagattga
     2881 aacattgaac ggacgtatcg gtgggtatct gtcgcgtgta gctacgcagc aggtcgtgat
     2941 gtatggcggc ttggttattc ttttattagt agcgggattg ttgttggtag tctataaatc
     3001 cctccgttcc aagaatcgcc tgaataaaga gttgtccgaa cagaagaaac aagtagagca
     3061 acagcgcgat aaactcgaag aacagcggga tcagcttatc cagctttctc atcaactgga
     3121 agaagcgact catgccaagc tggttttctt cacaaatata tctcacgatt ttcgtactcc
     3181 actgacatta gttgccgacc cggtagagca tttactggct gattcgtctt tgagtgaaga
     3241 tcagcgccga atgttattgt tagttcagcg aaacgtgaat atcctcttgc gtcttgtcaa
     3301 tcagattctg gattttcgta aatacgagaa tggaaaaatg gaatatactc ctatttcgtt
     3361 agacattctt tcttcttttg agggatggaa cgagtctttc atggcagcag cccggaagaa
     3421 acatattcat ttctcattcg attatatgcc ggatacggat taccgcacat tggcagatgt
     3481 agaaaagttg gaacgcatct atttcaacct cctttccaac gctttcaaat ttactccaga
     3541 gaatggaaaa gtaactgtac gcttatcttc cctgactaaa gacgatcatt gttggattcg
     3601 ctttactgtt gccaataccg gctcaatgat ttctgcggag catatccgga atattttcga
     3661 ccgtttctat aagatagata tgcaccatgc cggttcgggt attggactgg cattggtaaa
     3721 ggcttttgtg gaattgcata aaggtaccat cacggtggaa agtgatgaaa agcaaggaac
     3781 tatctttacc gttgatttgc ctgtacagac ttgcgagact gttgtttcag aaaactctcc
     3841 ggcattctct gtgcctgcta cttctgtaac ctctaccgat gctgcaacct ctgccgttgc
     3901 tggggctccc gtaactcctg caacttctgg ttattccggt tcttcgagct tgaatgatgc
     3961 tttaacttac gaagaagagg aattggaaaa aagttacgac tcttccaaac cttgcgttct
     4021 gattattgat gataacgctg atattcgctt atatgtgcat ggattgcttc acactgatta
     4081 tactgttata gaagctgcat acggctcgga aggtattcgt aaagctatga aatatgtccc
     4141 ggacttgatt atctccgatg taatgatgcc cggaatggat ggaattgaat gttgtcgtcg
     4201 cttgaaaagc gaattacaaa cctgtcatat tcctgttatc ctattgacag cttgttcttt
     4261 ggatgaacaa cgaattcaag ggtatgatgg tggtgcagat tcttatatct ccaagccttt
     4321 cagttcgcaa ttactattgg cacgcgttcg taatctgata gattcacacc gccgcctgaa
     4381 acagtttttt ggtgacggac aaacgttggc gaaagaggat gtctgtgata tggataaaga
     4441 ctttgtggaa aaattcaaag ctctgattga ggcaaagatg ggagattcaa atttgaatgt
     4501 agaagatttg ggtaaggata tgggattaag tcgtgtgcaa ctttaccgca agattaaatc
     4561 tctgactaat tattctccga atgaactgct tcgtatagct cgtttgaaga aagctgcctc
     4621 tctgcttgcc tcgtcggata tgacagtggc agagatcggt tatgaagttg gttttagttc
     4681 tccttcttat tttactaaat gttatagaga acagtttgga gagagtccga cagatttgtt
     4741 gaagaggaaa ggataggata gaatctgcaa aatttggtgg tgagcattta tctgtttata
     4801 cttctatgga attcatatga taaaaataag aggtaaggaa atctattgac ataccttacc
     4861 tcttatttaa ttcagtatat gatttactgt atatttatta attcataatc aacttattcg
     4921 tttttggctt attccaccat ctttggttct cttgacctcc cgatgttacc cattgttcaa
     4981 agtctggata tgcttccaag aagtttactt cttctctggc atgatgtaaa gatgcaggta
     5041 cttttaatcc ccatataaag ttgtcttcat ttacataact ttcgttgctg ttataataaa
     5101 ccgggctata accttttaag tggatttctt gtcctttatt agtttttgca atataaaagt
     5161 ccattttact gtcttgtagg cttttaacgt taacaggtga gttgaacacc aagtaaatgg
     5221 ccatcatttt tttaggcttt gttttttcat ttacctccgt attataatac ttgtatccgt
     5281 taggaatggc cggtttcttt agtgaaataa tcaattcccc ttttgggcct tttaggattt
     5341 tgatattttc agcctcttca ggattgttac gctcaagata catttgagtt tcttctaaat
     5401 caagttcatt atattgtact tctgccaagc ggatataaag attgtagtca tatatacctc
     5461 ctatagctct gatttggaat cctatcatta agtattctgc ataacattga ttgtgactcc
     5521 aataaaaacc gtcaatttgg aaattatacc atgcaacaaa atcattaaaa tcataatcgc
     5581 ctaaagctgg atacatatct tcgaacataa tagttccgtt gccatatccc ggataattga
     5641 agatgttgtt cgtttcaact tctttattag ctcttgtggt aactctggat aatgccgtag
     5701 cgttagcagg tactactata gaaatagtac cattactttc aacaggaaca gtttgtattt
     5761 cagagccatt accatatttt acatacacat tttttatata tgcaggaatt tcaattggga
     5821 gttccaattt tgatgtgttg gcatcgacat ccattcgaag catcaaagcc tcttcattgc
     5881 aattttcttc tagaaataca gaaatagtag cagttgattg actggcaatt ttcactttgg
     5941 cattttgaga acctttccag tcgaaatcgg caggtacttc caagtcagtc atcttctttt
     6001 ctttctcggg ttgtttactt tcatcataaa ggttcttctc acaggagctg aaagccagtg
     6061 ctcccaataa acaagaagcg aacaggatag ttttcttttt cataacagca gtgcttgttt
     6121 tgttaataat agggttgctt ttaatgggta caaaggtcgg gattatttgt aaataaagca
     6181 aataaagttg catattttat ttgaaatgct tttattattt gcaaattctt ttctttttat
     6241 ctagttttgg aactgaaata aagtaatgtt tgagtgatga aagattataa agtagataag
     6301 gcgagccttt ccgcatcctt ttgtcaagag gtgtatcagg ttgtccgaga aattccggta
     6361 ggtaaagttt ctacctatgg gggaattgcc gcattattgg gaatgtctca atgttcccgt
     6421 atggtggggc gtgctttgaa acagattccg gatgatttat ctgcgccttg tcatcgggtt
     6481 gtcaatgcgt cgggacggct tgttccgggt tggacagagc agaaacaact cttgttggaa
     6541 gaagggatct ctttcaaaca aaatggatgc gtagacttga aaaagcatct ttggaattac
     6601 tccgtacctg aatgaaattt gcatatttaa tctattttcc ttacctttgt gccaacaata
     6661 tgcaagaaca gactgttatt tatttatgaa aatactgttt tctactgttc attaagagga
     6721 taatcttatc aaattctatt ccttttaaac tactctgtct gtttttttta accatttaaa
     6781 aaacgtcgga ccgtcatgtt atcatgtgac atgactgaac catgcgaaca ttcaacttgt
     6841 ttatcgtaag tgagaataag gaatgcggca gttgaaaaca aaacaaatat tataatctaa
     6901 accaatatat tatatgagta aaatagaaat aaaggatttg taccttatct ttggtaacga
     6961 gaagcagaaa gccctcaaga tgttgaaaaa agataagagt aaagaggaaa ttctgaaaga
     7021 taccggttgt acggtaggag tgaaagatgc caatctttca attaatgaag gagagttttt
     7081 cgtgataatg ggactctcgg gaagtggaaa atcgacatta ctgcgttgta tcaatcgtct
     7141 gatacgtcct actaccgggc aagtgcttgt aaacggagta gatatatcta aaatttccga
     7201 aaaagaatta ttgcaggttc gtcggaaaga gctggcgatg gttttccaga atttcggtct
     7261 gttacctcac cgttccgtat tgagcaatat cgcgttcggc ctcgaacttc agggagtgaa
     7321 gaaagaggaa cgtgagaaga aagcgatgga aagcatgaag cttgtcggat tgaaaggata
     7381 tgaaaatcag atggtaggcg agctttccgg tggaatgcaa cagcgtgtcg gactggctcg
     7441 cgctctggct aataatcctg aagtgctttt aatggatgag gctttctctg ctctcgatcc
     7501 tctgattcgc gtacagatgc aggatgaact actggccttg caatcaaaga tgaaaaagac
     7561 gattgttttt attacccacg acttgagtga agcaattaag ctaggtgacc gtattgccat
     7621 catgaaagac ggagaagtgg tgcaggtagg tacttcggag gaaatcctga ctgaaccggc
     7681 taacgattat gtagcccgtt ttgttgaaaa cgtggatagg agcaaaatta ttaccgcctc
     7741 ttctttaatg attgacaaac cgttggtggc ccgtctgaag aaagaaggtc ccgaagtatt
     7801 gattcgtaag atgcgtgcga agaatatcac cgtattacct gtcatagacg ccgatgataa
     7861 actggtcgga gaagtacgtc tgaacgactt gcttaagtta cgtagcaaac aggaaaaatc
     7921 cattgaaacg attgtgcgta cagaagtaca ttctgtgttg gaggatacgg tgttggagga
     7981 tatacttcct ctaatgacaa agagcaattc gccggtatgg gtgattgatg agacgcgcga
     8041 gtttttagga acaatcccgc tttcatcctt aatcatcgaa gtgaccggga aagataaaga
     8101 agaaataaac gaaataattc aaaacgcaat agatttatga taaatatagg acaatatata
     8161 gagatggcca tcaattggat gatgatacat ttttccactt tctttgatgc cgtgaatgcg
     8221 ggcatcggta gttttattat aggattccaa cacatacttt tcggaatacc tttttatata
     8281 accattttgg tacttgctgc actcgcatgg atgaaagcag gacgcggtac ggcaattttc
     8341 accgcattgg gattattact gatctatgga atgggattct gggaggctac catgcaaact
     8401 ctagctctcg ttttttcatc tacctgtctg gccctgattg ttggtgtacc tttaggagta
     8461 tggacggcaa acagttcgcg tgcagagaaa atactccgtc ctgttctcga cttgatgcag
     8521 acgatgcctg cttttgttta tctgattcct gctgttttgt ttttcggatt gggagcagtg
     8581 ccaggagtgt ttgccaccat tatctttgct atgcctcctg tggtccgcct taccggattg
     8641 ggaatccggc aagttcctaa aaatgtagtg gaagcttccc gttcgttcgg agctacccgt
     8701 tggcagttat tgtataaagt gcagcttcct ttggcgttgc ccaccattct gactggtgtc
     8761 aaccagacaa taatgatgtc gctttctatg gttgtaattg ctgccatgat tgctgccggt
     8821 ggtctgggag aaattgtatt gaaaggtatt acccaaatga aaatcggact tgggtttgaa
     8881 ggtggtatag cagttgttat tttagctatc atcttagacc gtatcacgca aggaatggca
     8941 ggacgaaaaa ataagaacta aacggaaagg ataaaatacg tatgagaata tataaaatag
     9001 taggaatagt attgtcagct atgcttttgc tagcttcctg tactaattca gacttagaga
     9061 aaaagaaagt aaaaatagcc tatgccaatt ggctggaagg tattgccatg agtcatttgg
     9121 ctaaggtggt attggaagag catggatatg aggttgaatt gcaaaatgct gatcttgccc
     9181 ctatttttgt atctatgtca ggaaagaaat cagatgtgtt tctggatgca tggttaccaa
     9241 taacgatgaa agattatatg gatcagtatg gagacagtat cgaatttctg ggtgaggtat
     9301 atggagaggc ccgtgtagga ctagttgttc ctcaatatgt tacgatccag tctattagtg
     9361 agctggaagc taataaagac cgtttctctt ctgaaatagt aggaattgat gcgggagcag
     9421 ggataatgaa gacgaccgat aaggccattg ctgcttacgg acttgatggg tataccctca
     9481 tgacttcaag tagttccacc atgctggctt ctttgaaaaa agcgatggat aaaggagaat
     9541 ggatggtcat cacggggtgg acaccacatt ggatgtttga cctgttttat ttgaaattct
     9601 tggatgatcc gaagaaagta tatggagact tggaagaaat acatgctatt gcatggaaag
     9661 gattcagtga gaaagatccg tttgctgccg aattctttgg caacatcaaa ctaacgacag
     9721 aagaacttag ctcttttatg acagctatga aggatgcccg gatggatgaa gaagaaatag
     9781 cccgcaaatg gagggatgag catcggctgt tggtggatag ttggattccg aagtcagaga
     9841 ataaatagat tggagcattg ttatttttaa ttttaaatat aaaatagaca tgaactctag
     9901 tgggaaaaag ggagtactgt ttatgttgga cagagttcat acaataaaaa agcggtaatc
     9961 ttatcaaaga ttaccgcttt atatttatag ggtattacta ttattcagca ccccagtttt
    10021 ctctagccaa acgtttgtag ctgttgtaac gccatttagc gttttcttca gcagctttaa
    10081 acagttcttc agcttcagta ggatattgtt tcattacaga agcgtaacga acttcaccct
    10141 tcaagaaacc ttggaaatct tcccagttcg gttctttgct atccaattgg aatgggttct
    10201 tgccttcttc ttccaaagct gggttgtaac gccacaagtg ccagtaaccg cacttaacag
    10261 ctttttcttc ttcttcctgg ctcttaccca tacctgcttt cagaccgtgg ttgatacatg
    10321 gagcgtaagc gataatcaaa gatggtcccg gatatgcttc agcttcacgg atagctttca
    10381 gagtttgagc ttggtcagca cccatagcga tctgtgcaac atatacataa ccgtaagtag
    10441 tagccatcag accgaggtct ttcttacgta cgcgcttacc agcagcagcg aacttagcga
    10501 tagcacctac cggagtagct ttagaagact gaccacctgt gttagagtaa acttcagtat
    10561 ccagaacgag aatgttaacg tccttaccgg aagcgattac atggtcaaga ccaccgtaac
    10621 cgatatcgta agaagcaccg tcaccaccaa tgatccactg gctgcgtttt acaagatatt
    10681 gagtcagacc tttcagttct ttgctaacag gacatccggc agcgatacct tgttcgatga
    10741 tagcttcgat ttgaggagcc aattcttttg tcttgtcagc atcgtacatg ttttcaatcc
    10801 atgccttcaa tacttcttta gcttcagcag gagcgttatc gccttccaaa atctggttga
    10861 ataacttcac gatacgagca cgcatctttt cgttagccaa ttccataccc agaccgaatt
    10921 cacagaagtc ttcgaacagt gagttagccc aagcaggacc gtgaccgttt tcgttcgtag
    10981 tatacggagt agaaggaact gaaccagagt agatagaaga acatccggta gcgttagcaa
    11041 ccatttcacg gtcaccgaac aattgagaaa tcaatttcac atacggagtt tcaccacaac
    11101 cagagcaagc accagagaac tcaaacaacg gagtagcgaa ctgtgagttc ttcacgttag
    11161 acttgatatc aacaagatgt tgtttagtct tcacgttttc agcacagtaa gtccagttgt
    11221 cagcttcagc caattggctt tcgaggtgtt tcattgtcaa tgctttgcca cccttcttcg
    11281 gattacccgg acagatgtca gcacagttac cgcaacccag acagtcgaga acgtcaacct
    11341 ggatacggaa tgtcataccg tcgaatactt tacctactgc tttcaattgt tcgaacttag
    11401 cacccttctg ctcttcagca tcgagtacga acggacggat agaagcgtga ggacaaacgt
    11461 atgcacactt gttacactgg atacagtttt ctggattcca ttcaggaacg aatgcggcta
    11521 caccacgttt ttcgtattta gaagtacctt gataccaagt accgtcttcg atacccttga
    11581 atgcagatac aggcagcaag tcaccatctt gtgcattgat cggacgaact acttcgttga
    11641 tgaatgcagg atcgttgttt tcagcttttg catcatccgg caggttagcc caagcaggat
    11701 caacagctaa agtcttgtat tcaccaccac ggtcaacggc agcatagttc ttgttaacaa
    11761 cgtcttcacc cttcttaccg taagacttaa cgatgaattt cttcatctgt tcaacagcct
    11821 ggtctacagg aataacacct gtgatacgga agaatgcaga ttgaaggata gtgttggtac
    11881 gattacccaa accaatttcc aatgcaatct gtgttgcgtt gatatagtat acggaaatgt
    11941 tgttctgtgc aaaatatttc ttaaccttgt taggcaggtt cttagccagt tcttcacctt
    12001 cccagatagt gttcagcaag aaagaaccgt tcttacgcaa accacgagtt acatcgtaca
    12061 tgtgcaggta agcctgaacg tgacaagcaa cgaagttcgg agtatttacc aaataagtgg
    12121 aacggatcgg agtatcaccg aaacgcaagt gagaacaagt gaaaccacct gacttcttag
    12181 agtcataaga gaagtaagcc tggcagtgtt tgtcagtgtt gtcaccgata atctttacag
    12241 agttcttgtt agcacctact gtaccgtcag cacccaaacc gtagaattta gcttcgaaca
    12301 ttccttcacc gcctaaagcg atttcttctt tttgaggaag agaagtgaaa gtaacgtcgt
    12361 ctacgatacc gatagtgaag tgattcttcg gcattggcat ggccaagttt tcgaatactg
    12421 aaagaatttg agcaggagta gtatcttttg aacccaaacc gtagcgaccg ccaacgataa
    12481 ccggagcatt ttctgcgccg tagaagcagt ctttaacgtc aaggtaaaga ggttcgccgt
    12541 tagcgcccgg ttctttagta cggtcaagaa ctgcgatagt cttggcagtc ttaggtacag
    12601 cagccaggaa gtgtttagca gagaacggac gatacaggtg tacggcaacc atacccactt
    12661 tttcgccatt tgctaccaag tggtcgatag cttcgcgggc agcttctgtt acagaaccca
    12721 tagcgataat tacgcgttct gcatcttctg caccataata atcgaacaaa ccgtatttac
    12781 gacctgtaat cttagaaatt tcattcatgt attcttctac gatagcagga actgcttcat
    12841 agtagttgtt acatgattca cgatgttgga agaagtggtc ggggttttca gccataccac
    12901 gagcaaccgg attcatcgga ttcagtgcgc gggcacggaa ttcagccaaa gcttcctgat
    12961 cgatcagcgg agcaagatca tcattttcca acatttcaat cttctggatt tcgtgagatg
    13021 tacggaaacc atcgaagaag ttcatgaacg gaacgcgaga tttgatggta gccaagtgag
    13081 caacaccagc caaatccata acttcctgta cagagccttc agccaacatc gcaaagccag
    13141 tctgacgagc tgacattacg tcttggtggt caccgaagat acacaatgcg tgagaagcca
    13201 atgtacgagc agatacatgg aatacgcaag gcaagaactc accggcaatt ttgtacatat
    13261 tagggatcat caggagaagc ccctgagaag cagtgtaagt agtagtcaac gcaccagcct
    13321 gaagagaacc gtgaactgca ccggcagcac caccttcaga ttgcatttcc tgtaccaata
    13381 ctgtttcgcc gaagatgttc ttacgtcctg cggcagccca ttcgtctacg tactcagcca
    13441 tagtcgaaga aggagtgatg gggtagatag cagctacttc agagaacata tacgagatat
    13501 gcgctgcagc ctggttacca tcacaagtga tgaatttctt ctgtttagtc ataactaaat
    13561 taaatattta agtaaataaa tcttttaata taaaaagccg aacatccaga gaggtatctg
    13621 gttgccccga cctatttcag ccttatgcaa cgcgtacgtc acattcagat tgttcttgat
    13681 ctttgctcct tcctggcaaa ttttgaacgg cattacttcg tccaccataa aagagacgtt
    13741 tttatctcct ttatgtacct tatggtcttt ccataaagaa tttgcaaaga atgtgtcgag
    13801 tacatcctgc tcctccactt tcacaggata gatggaatac atcaggttgg agttgtgcat
    13861 cattatcttg gaaggttttt taggaaattc ttctcctttc ggataaacca gattaatgag
    13921 tcgcgcatct gccagatact tgatatagtt catcaccgtg gcgcgagatg tctgtatgtc
    13981 gcttgccagt tgactcacat tgggagcctt cggtccgtcg acagcgagca aatatagtaa
    14041 tttttttatc tttgaaagat atttcagttc aatttgtttg atgagcagga tatctacttc
    14101 caccatcatg ttcatcgttt tcagcaaatt ctccgaaaag ttacgcttct cgaggaagaa
    14161 tggatagaac ccatgatgca ggtaatcctg gaagtaatcc agcggacgaa ctttagagag
    14221 tactcctttg gcaatctgtt cgtgagtgct aagaatttct tcgagactgt aggccctgaa
    14281 tttcatgcct gtttgtaagt tcaggtattc gcggaaagaa aatccgcgca ggttatagct
    14341 ttttgcaata tcacgcaatt caagattttc ctctttcagt cgcattacag atgagccggt
    14401 aaagacaatt ttcaaattag gaaaacggtc gtaacacatg cgcaactctc tgctccattc
    14461 cgggtgtttg aacacttggt cgatcaacaa tacttttcca ccacgtttct ggaattcgtt
    14521 agcaaagtct acaatgctgt ggccagagaa gtagaagttg ttcatgttga tgaacaggca
    14581 ggagcggtcg ttcccaaatt tttctttggc gtattggaga aggaaagtgg tttttcctac
    14641 gccacgtgtc cctttgatac caatcaggcg gtcgctccag tcgatctcgt ccataagatc
    14701 gcggcgaacg ggggcattgg tgtgctcaac gaggtaggcg tgtgtgcgat agaatgattc
    14761 catttcagtt ctttgttttt cgggtggcaa atatactgct ttttttagga tttgcaaagt
    14821 agagatggca aaattgtgag tttaattaga actttctgtt tattgtagcc attcctgact
    14881 atttcctgta tatatttgca gaataaagtt ttgaattcgt ttaaaatgac aaaaaaggct
    14941 ctttatatat tcaatccgga acatgatttg gcgttagcca gcggtgaaac aaactatatg
    15001 gcaccggctt ccgcccggca gatggcatcc gaattggctt tgttgccgat gtggtatgca
    15061 gaagagggaa gtgttgtatt ggctccttcc gcttataatc tcgactatgt gaagaagata
    15121 caggaattat taggactttc ggttgatttg atgacagaac ctgaacttgc ttcggagcgg
    15181 aatttggata ttcgtccttg gggctgggat atagcaataa gaaaacgact gttggatttg
    15241 ggagtggaag aaagcgagct tccttctatt gagcaattgg ataaactgcg tttctgttcc
    15301 catcgttcct gtgctgtggg attattacca cagctacaac tgggagcctg tttttgtgga
    15361 gagtcttttt acctgacgtt tcccgaagaa tggaagtcat ttgtagaatc acatgatact
    15421 tgtttactga aagctccttt atccggtagc ggaaaagggt tgaattggtg caaaggtgta
    15481 tatactcctt ccatttccgg ttggtgctca cgcattggca accagcaagg aggtgttatt
    15541 ggcgaacctc tatataataa ggtggaagat tttgctatgg aatttcgttc ttcgggtaat
    15601 ggtcgatttg gttttgccgg atactctcaa ttccgtacgg gtggaagtgg ggcgtacgaa
    15661 ggtaatctgc tgatttcaga tgcagccatc gaacggaatc tttcggaata tatccctgtc
    15721 gaagaaattt ataaattgcg cgaccgcctt gaacaagaat tatccctccg tttcggaacc
    15781 atttataatg gttatttggg agtggatatg atgatctgtc gctttccaga atctcctgtt
    15841 tatcggattc atccttgcgt ggaaatcaac ttgaggatga atatgggagt agtagcgcgt
    15901 catatttatg accattatat ctatcctact tcaacaggag cttttcaaat aagctattac
    15961 cctacggaag gaacagcctg gagagcacac aaagaaatgg aggaggctta tcctttggaa
    16021 atagaacaag gaagaataaa atcaggctat ttgtcattgg tgccggctca taaaaagagt
    16081 agttatcggg cgtgggtgtt tatctcaaaa agcgtgtttt tgtgatatta tatcgaagtt
    16141 atggtttctc ggtgtgaaac tgatagtttc atgtagtgaa accattggtt ccacaccgag
    16201 aaacaaaaag ttttattgca tgaaacaagt aatcacatgc catgtgtgta ctgtactgga
    16261 tttagttgac aacttcgctt gttataccta agttagttta ctcaatattt tttaaaacct
    16321 aaataagttt actt
//
