LOCUS       gnlProkkaMEGCPJPM_13    2817 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MEGCPJPM_13.
ACCESSION   gnlProkkaMEGCPJPM_13
VERSION     gnlProkkaMEGCPJPM_13
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 10:27:34
            Original ID  :: gnl|Prokka|MEGCPJPM_13
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2817
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2817
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:2817]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..2817
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..2817
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2817
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             1..2817
                     /NRPS_PKS="Domain: PCP (43-109). E-value: 6.6e-25. Score:
                     79.0. Matches aSDomain: nrpspksdomains_ctg13_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (127-412). E-value:
                     2.2e-105. Score: 343.8. Matches aSDomain:
                     nrpspksdomains_ctg13_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (579-939). E-value:
                     1.1e-105. Score: 345.4. Matches aSDomain:
                     nrpspksdomains_ctg13_1_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     355.3; E-value: 9.8e-108)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_1"
                     /sec_met_domain="PP-binding (E-value: 1.3e-17, bitscore:
                     50.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.2e-91, bitscore:
                     292.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-99, bitscore:
                     319.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYFIQLEKMPLTSNGKIDRKALPLPDRNTQTGVKYVAPRTSIEL
                     KLAEIWKEVLSLKQVGIRDNFFDIGGHSLKATSLAAKIYKILNLRVSVRQIFNHPTIEQ
                     LSSRIISAVEDQSFTSIPAVEQRESYPVSSAQKRMYILHQLEGGELSYNMPNLMVVEGE
                     LDVTKLESACIQLIDRHESLRTSFKLLDGELKQLIHDKVNFKVEVRKVRPEDLDEYIQG
                     FIRAFDLKQAPLFRVQVLEFTSTKHMILMDMHHVISDGVSMTVIMQELFQLYEGAQLPE
                     LRIQYKDYAVWQQNEMNQEQIRKQGAYWLETLGGDLPVLQMPTDYARPATRNFKGARVE
                     FTIDEHRSEALQQLAMQTGSTLYMVMLSIYTLMLSKYSGQEDIIIGSPIAGRPHADLDR
                     VVGMFVNTLAMRNYPTGEKTFEQFASEVKENALRAYENQDYPFEEIVETLDVTRDMSRN
                     AIFDVMFVLQNMDQEARKVEGLEIKPFEWEYEIAKFDLTLSVVEWNGQLNCMLEYATSL
                     YEEATIVRMTKHFIHLVDNILAHPDTKLSELSMVLEEERMQLLGDFNDTKAEYPRNKTI
                     HQLFEEQAERVPDKVAVVFEDKQLTYRELNERANQLARTLRNEGVEAEQLVGIMTERSL
                     EMIVGILGILKAGGAYVPIDPEYPEERIRYMIEDSGVKLLLKQSHKQHIEFTGTVLNLD
                     QESNYHKNSLNLENHVQSNNLAYVIYTSGTTGAPKGTLLEHKNVVRLLFNSKNVFDFNE
                     KDTWTLFHSFCFDFSVWEMYGALLYGGKLVIVPKTISKNPIQFLQLLKDEEVTILNQTP
                     SYFYLVKDQELTHSSCDLKVRKVIFGGESLNPSLLKEWKDKYPDIKLINMYGITETTVH
                     VTYKEITEIEIKDGRSNIGKPIPTLNAYILNEQKELQPIGIQGELYIAGEGLARGYLNR
                     PDLTAEKFV"
     aSDomain        130..327
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg13_1_PCP.1"
                     /evalue="6.60E-25"
                     /label="ctg13_1_PCP.1"
                     /locus_tag="ctg13_1"
                     /protein_end="109"
                     /protein_start="43"
                     /score="79.0"
                     /tool="antismash"
                     /translation="ELKLAEIWKEVLSLKQVGIRDNFFDIGGHSLKATSLAAKIYKILN
                     LRVSVRQIFNHPTIEQLSSRI"
     aSDomain        382..1236
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg13_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.20E-105"
                     /label="ctg13_1_Condensation_LCL.1"
                     /locus_tag="ctg13_1"
                     /protein_end="412"
                     /protein_start="127"
                     /score="343.8"
                     /tool="antismash"
                     /translation="ESYPVSSAQKRMYILHQLEGGELSYNMPNLMVVEGELDVTKLESA
                     CIQLIDRHESLRTSFKLLDGELKQLIHDKVNFKVEVRKVRPEDLDEYIQGFIRAFDLKQ
                     APLFRVQVLEFTSTKHMILMDMHHVISDGVSMTVIMQELFQLYEGAQLPELRIQYKDYA
                     VWQQNEMNQEQIRKQGAYWLETLGGDLPVLQMPTDYARPATRNFKGARVEFTIDEHRSE
                     ALQQLAMQTGSTLYMVMLSIYTLMLSKYSGQEDIIIGSPIAGRPHADLDRVVGMFVNTL
                     AMRN"
     aSModule        382..2817
                     /domains="nrpspksdomains_ctg13_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg13_1_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg13_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       451..561
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0001"
                     /evalue="2.00E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg13_1"
                     /protein_end="187"
                     /protein_start="150"
                     /score="39.5"
                     /tool="antismash"
                     /translation="SYNMPNLMVVEGELDVTKLESACIQLIDRHESLRTSF"
     CDS_motif       757..822
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0002"
                     /evalue="6.00E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg13_1"
                     /protein_end="274"
                     /protein_start="252"
                     /score="31.6"
                     /tool="antismash"
                     /translation="MHHVISDGVSMTVIMQELFQLY"
     CDS_motif       853..888
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0003"
                     /evalue="1.90E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg13_1"
                     /protein_end="296"
                     /protein_start="284"
                     /score="17.2"
                     /tool="antismash"
                     /translation="QYKDYAVWQQNE"
     CDS_motif       1144..1233
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0004"
                     /evalue="3.40E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg13_1"
                     /protein_end="411"
                     /protein_start="381"
                     /score="51.5"
                     /tool="antismash"
                     /translation="DIIIGSPIAGRPHADLDRVVGMFVNTLAMR"
     CDS_motif       1282..1401
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0005"
                     /evalue="8.40E-19"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg13_1"
                     /protein_end="467"
                     /protein_start="427"
                     /score="60.0"
                     /tool="antismash"
                     /translation="KENALRAYENQDYPFEEIVETLDVTRDMSRNAIFDVMFVL"
     aSDomain        1738..2817
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg13_1_AMP-binding.1"
                     /evalue="1.10E-105"
                     /label="ctg13_1_AMP-binding.1"
                     /locus_tag="ctg13_1"
                     /protein_end="939"
                     /protein_start="579"
                     /score="345.4"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEEQAERVPDKVAVVFEDKQLTYRELNERANQLARTLRNEGVEAE
                     QLVGIMTERSLEMIVGILGILKAGGAYVPIDPEYPEERIRYMIEDSGVKLLLKQSHKQH
                     IEFTGTVLNLDQESNYHKNSLNLENHVQSNNLAYVIYTSGTTGAPKGTLLEHKNVVRLL
                     FNSKNVFDFNEKDTWTLFHSFCFDFSVWEMYGALLYGGKLVIVPKTISKNPIQFLQLLK
                     DEEVTILNQTPSYFYLVKDQELTHSSCDLKVRKVIFGGESLNPSLLKEWKDKYPDIKLI
                     NMYGITETTVHVTYKEITEIEIKDGRSNIGKPIPTLNAYILNEQKELQPIGIQGELYIA
                     GEGLARGYLNRPDLTAEKFV"
     CDS_motif       1924..1965
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0006"
                     /evalue="3.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg13_1"
                     /protein_end="655"
                     /protein_start="641"
                     /score="20.0"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPID"
     CDS_motif       2146..2205
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0007"
                     /evalue="3.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg13_1"
                     /protein_end="735"
                     /protein_start="715"
                     /score="28.9"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGAPKGTLLEH"
     CDS_motif       2725..2814
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0008"
                     /evalue="2.00E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg13_1"
                     /protein_end="938"
                     /protein_start="908"
                     /score="55.2"
                     /tool="antismash"
                     /translation="PIGIQGELYIAGEGLARGYLNRPDLTAEKF"
ORIGIN
        1 ccatcttatt ttattcagct ggagaaaatg ccgctgacat ctaacgggaa aattgaccgt
       61 aaggcactcc ctctgcctga tcgaaataca caaactgggg taaaatatgt tgcacctcgt
      121 acatcaattg aattaaagct ggctgagatt tggaaagagg tacttagctt aaaacaagtg
      181 ggaatacgag ataatttctt tgacatagga ggacattctt taaaagctac tagtttagca
      241 gcaaagattt ataagatatt aaatttaaga gtatctgttc gacaaatatt taaccatcca
      301 acgatagaac aattatcatc aagaatcata agtgctgtgg aagatcaaag ctttacatct
      361 atccctgctg tggaacagag agaatcttat ccggtttctt ctgcacaaaa acgaatgtat
      421 atcttgcatc aattagaagg cggagaattg agctacaaca tgcccaactt gatggtggtt
      481 gaaggagaac tagatgttac taaactggag tctgcctgca ttcaattgat tgatcgccat
      541 gaatctttac ggacaagttt taaattattg gatggtgagt tgaaacagct tattcatgat
      601 aaagttaatt ttaaagtaga agttcgaaag gtgagaccag aggatttaga tgaatatatt
      661 cagggattta tacgtgcttt tgatttaaag caggctcctc ttttccgagt tcaggttctt
      721 gagttcacat caacaaagca tatgatacta atggatatgc atcatgttat ttcagatggc
      781 gtatcaatga ctgtaatcat gcaagagtta tttcaattat atgagggtgc ccaattacct
      841 gaactgcgta ttcaatataa agattatgca gtgtggcaac aaaatgaaat gaaccaagaa
      901 cagattcgaa aacaaggagc atattggtta gagacgcttg gaggagatct tcctgtttta
      961 caaatgccta ctgactacgc gagaccagct acccgaaatt ttaagggagc aagagttgag
     1021 tttacgattg atgagcacag aagtgaggcg ctccaacaac tagctatgca aacgggttct
     1081 acactatata tggtaatgtt atcaatttac acgcttatgt tgtctaaata tagcggacaa
     1141 gaagacatta ttataggcag tccaattgca ggtcgcccac atgctgattt ggatcgagtt
     1201 gtcggaatgt ttgtgaacac gttggcaatg cgaaactacc caacagggga aaaaacattt
     1261 gagcaatttg cgagtgaagt gaaagaaaat gccttaagag catatgaaaa tcaagattat
     1321 ccatttgaag aaattgtgga gacattagat gtcaccagag atatgagcag aaacgcgatc
     1381 tttgatgtca tgtttgtatt gcaaaatatg gatcaagaag ccaggaaagt agaaggatta
     1441 gaaataaagc cgtttgaatg ggagtatgag atagccaaat ttgatttgac gttgagtgta
     1501 gttgaatgga acggacaatt gaactgtatg ttggaatatg cgacatcttt atatgaggaa
     1561 gcaacgatag tacgaatgac aaaacatttt atccatctgg tagataacat tttggcacat
     1621 ccggatacaa aactatcaga actatctatg gtcctcgaag aggagcgaat gcagcttctc
     1681 ggagatttca atgacacaaa agcggaatat ccaagaaaca aaacaattca tcaactgttt
     1741 gaagaacaag cagaacgtgt accagataag gtagctgttg tgtttgaaga taaacaattg
     1801 acatatcgtg aactgaatga gcgagctaat caactagccc gtacacttcg aaatgaagga
     1861 gtagaggctg aacagcttgt tggaattatg acagaacgtt ctcttgaaat gattgtaggt
     1921 atactgggta ttctcaaagc gggcggggca tatgtgccga ttgatccgga atatccagaa
     1981 gagcgaattc gttacatgat tgaggactca ggagtgaaac tattattaaa gcaaagccat
     2041 aagcagcata tagaatttac tggcacagtg ctgaatctag atcaggaaag taactatcat
     2101 aaaaatagct tgaatcttga aaaccatgta cagtcaaaca atttagcata tgtgatctat
     2161 acgtcgggga caacaggtgc tccaaaaggc actttgcttg aacataaaaa tgtggttcgt
     2221 ctcttgttta acagcaaaaa tgtttttgat tttaatgaaa aagatacgtg gaccttattc
     2281 cactctttct gtttcgactt ttctgtatgg gaaatgtatg gagcactttt gtacggtggc
     2341 aaattagtaa tagtaccaaa aacgatatca aagaacccga tacaattttt acagttgtta
     2401 aaagatgagg aagtaacaat tctaaatcaa actcctagtt atttttattt agtgaaagat
     2461 caagaattaa ctcattcttc gtgtgatcta aaagtgagaa aagtaatctt tggcggggaa
     2521 tcattgaatc catctttatt aaaagaatgg aaagataaat atccagacat aaagctaatt
     2581 aatatgtatg gtattacaga aacaaccgtt catgtaacat ataaagagat tacagaaatc
     2641 gaaataaaag atggaagaag taacatcgga aaaccgattc ctacattaaa tgcctatata
     2701 ttaaatgagc aaaaagaatt gcagccaatc ggaatacagg gagagctata tattgccgga
     2761 gagggtctag ctcgaggcta cttaaaccgc ccggatttaa cggccgaaaa gtttgtc
//
