LOCUS       gnlProkkaMEGCPJPM_3     2817 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MEGCPJPM_3.
ACCESSION   gnlProkkaMEGCPJPM_3
VERSION     gnlProkkaMEGCPJPM_3
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 10:27:34
            Original ID  :: gnl|Prokka|MEGCPJPM_3
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2817
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     aSDomain        complement(1..1080)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg3_1_AMP-binding.1"
                     /evalue="1.10E-105"
                     /label="ctg3_1_AMP-binding.1"
                     /locus_tag="ctg3_1"
                     /protein_end="939"
                     /protein_start="579"
                     /score="345.4"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEEQAERVPDKVAVVFEDKQLTYRELNERANQLARTLRNEGVEAE
                     QLVGIMTERSLEMIVGILGILKAGGAYVPIDPEYPEERIRYMIEDSGVKLLLKQSHKQH
                     IEFTGTVLNLDQESNYHKNSLNLENHVQSNNLAYVIYTSGTTGAPKGTLLEHKNVVRLL
                     FNSKNVFDFNEKDTWTLFHSFCFDFSVWEMYGALLYGGKLVIVPKTISKNPIQFLQLLK
                     DEEVTILNQTPSYFYLVKDQELTHSSCDLKVRKVIFGGESLNPSLLKEWKDKYPDIKLI
                     NMYGITETTVHVTYKEITEIEIKDGRSNIGKPIPTLNAYILNEQKELQPIGIQGELYIA
                     GEGLARGYLNRPDLTAEKFV"
     aSModule        complement(1..2436)
                     /domains="nrpspksdomains_ctg3_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg3_1_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg3_1"
                     /tool="antismash"
                     /type="nrps"
     protocluster    1..2817
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:2817]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..2817
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..2817
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2817
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(1..2817)
                     /NRPS_PKS="Domain: PCP (43-109). E-value: 6.6e-25. Score:
                     79.0. Matches aSDomain: nrpspksdomains_ctg3_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (127-412). E-value:
                     2.2e-105. Score: 343.8. Matches aSDomain:
                     nrpspksdomains_ctg3_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (579-939). E-value:
                     1.1e-105. Score: 345.4. Matches aSDomain:
                     nrpspksdomains_ctg3_1_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     354.3; E-value: 1.9e-107)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_1"
                     /sec_met_domain="PP-binding (E-value: 1.3e-17, bitscore:
                     50.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.2e-91, bitscore:
                     292.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-99, bitscore:
                     319.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYFIQLEKMPLTSNGKIDRKALPLPDRNTQTGVKYVAPRTSIEL
                     KLAEIWKEVLSLKQVGIRDNFFDIGGHSLKATSLAAKIYKILNLRVSVRQIFNHPTIEQ
                     LSSRIISAVEDQSFTSIPAVEQRESYPVSSAQKRMYILHQLEGGELSYNMPNLMVVEGE
                     LDVTKLESACIQLIDRHESLRTSFKLLDGELKQLIHDKVNFKVEVRKVRPEDLDEYIQG
                     FIRAFDLKQAPLFRVQVLEFTSTKHMILMDMHHVISDGVSMTVIMQELFQLYEGAQLPE
                     LRIQYKDYAVWQQNEMNQEQIRKQGAYWLETLGGDLPVLQMPTDYARPATRNFKGARVE
                     FTIDEHRSEALQQLAMQTGSTLYMVMLSIYTLMLSKYSGQEDIIIGSPIAGRPHADLDR
                     VVGMFVNTLAMRNYPTGEKTFEQFASEVKENALRAYENQDYPFEEIVETLDVTRDMSRN
                     AIFDVMFVLQNMDQEAGKVEGLEIKPFEWEYEIAKFDLMLTVVEWNGQLNCMLEYATSL
                     YEEATIVRMTKHFTHLVDNILAHPHTKLSELSMVLEEERMQLLRDFNDTKAEYPRNKTI
                     HQLFEEQAERVPDKVAVVFEDKQLTYRELNERANQLARTLRNEGVEAEQLVGIMTERSL
                     EMIVGILGILKAGGAYVPIDPEYPEERIRYMIEDSGVKLLLKQSHKQHIEFTGTVLNLD
                     QESNYHKNSLNLENHVQSNNLAYVIYTSGTTGAPKGTLLEHKNVVRLLFNSKNVFDFNE
                     KDTWTLFHSFCFDFSVWEMYGALLYGGKLVIVPKTISKNPIQFLQLLKDEEVTILNQTP
                     SYFYLVKDQELTHSSCDLKVRKVIFGGESLNPSLLKEWKDKYPDIKLINMYGITETTVH
                     VTYKEITEIEIKDGRSNIGKPIPTLNAYILNEQKELQPIGIQGELYIAGEGLARGYLNR
                     PDLTAEKFV"
     CDS_motif       complement(4..93)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg3_1_0008"
                     /evalue="2.00E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg3_1"
                     /protein_end="938"
                     /protein_start="908"
                     /score="55.2"
                     /tool="antismash"
                     /translation="PIGIQGELYIAGEGLARGYLNRPDLTAEKF"
     CDS_motif       complement(613..672)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg3_1_0007"
                     /evalue="3.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg3_1"
                     /protein_end="735"
                     /protein_start="715"
                     /score="28.9"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGAPKGTLLEH"
     CDS_motif       complement(853..894)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg3_1_0006"
                     /evalue="3.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg3_1"
                     /protein_end="655"
                     /protein_start="641"
                     /score="20.0"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPID"
     CDS_motif       complement(1417..1536)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg3_1_0005"
                     /evalue="8.40E-19"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg3_1"
                     /protein_end="467"
                     /protein_start="427"
                     /score="60.0"
                     /tool="antismash"
                     /translation="KENALRAYENQDYPFEEIVETLDVTRDMSRNAIFDVMFVL"
     aSDomain        complement(1582..2436)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg3_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.20E-105"
                     /label="ctg3_1_Condensation_LCL.1"
                     /locus_tag="ctg3_1"
                     /protein_end="412"
                     /protein_start="127"
                     /score="343.8"
                     /tool="antismash"
                     /translation="ESYPVSSAQKRMYILHQLEGGELSYNMPNLMVVEGELDVTKLESA
                     CIQLIDRHESLRTSFKLLDGELKQLIHDKVNFKVEVRKVRPEDLDEYIQGFIRAFDLKQ
                     APLFRVQVLEFTSTKHMILMDMHHVISDGVSMTVIMQELFQLYEGAQLPELRIQYKDYA
                     VWQQNEMNQEQIRKQGAYWLETLGGDLPVLQMPTDYARPATRNFKGARVEFTIDEHRSE
                     ALQQLAMQTGSTLYMVMLSIYTLMLSKYSGQEDIIIGSPIAGRPHADLDRVVGMFVNTL
                     AMRN"
     CDS_motif       complement(1585..1674)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg3_1_0004"
                     /evalue="3.40E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg3_1"
                     /protein_end="411"
                     /protein_start="381"
                     /score="51.5"
                     /tool="antismash"
                     /translation="DIIIGSPIAGRPHADLDRVVGMFVNTLAMR"
     CDS_motif       complement(1930..1965)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg3_1_0003"
                     /evalue="1.90E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg3_1"
                     /protein_end="296"
                     /protein_start="284"
                     /score="17.2"
                     /tool="antismash"
                     /translation="QYKDYAVWQQNE"
     CDS_motif       complement(1996..2061)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg3_1_0002"
                     /evalue="6.00E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg3_1"
                     /protein_end="274"
                     /protein_start="252"
                     /score="31.6"
                     /tool="antismash"
                     /translation="MHHVISDGVSMTVIMQELFQLY"
     CDS_motif       complement(2257..2367)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg3_1_0001"
                     /evalue="2.00E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg3_1"
                     /protein_end="187"
                     /protein_start="150"
                     /score="39.5"
                     /tool="antismash"
                     /translation="SYNMPNLMVVEGELDVTKLESACIQLIDRHESLRTSF"
     aSDomain        complement(2491..2688)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg3_1_PCP.1"
                     /evalue="6.60E-25"
                     /label="ctg3_1_PCP.1"
                     /locus_tag="ctg3_1"
                     /protein_end="109"
                     /protein_start="43"
                     /score="79.0"
                     /tool="antismash"
                     /translation="ELKLAEIWKEVLSLKQVGIRDNFFDIGGHSLKATSLAAKIYKILN
                     LRVSVRQIFNHPTIEQLSSRI"
ORIGIN
        1 gacaaacttt tcggccgtta aatccgggcg gtttaagtag cctcgagcta gaccctctcc
       61 ggcaatatat agctctccct gtattccgat tggctgcaat tctttttgct catttaatat
      121 ataggcattt aatgtaggaa tcggttttcc gatgttactt cttccatctt ttatttcgat
      181 ttctgtaatc tctttatatg ttacatgaac ggttgtttct gtaataccat acatattaat
      241 tagctttatg tctggatatt tatctttcca ttcttttaat aaagatggat tcaatgattc
      301 cccgccaaag attacttttc tcacttttag atcacacgaa gaatgagtta attcttgatc
      361 tttcactaaa taaaaataac taggagtttg atttagaatt gttacttcct catcttttaa
      421 caactgtaaa aattgtatcg ggttctttga tatcgttttt ggtactatta ctaatttgcc
      481 accgtacaaa agtgctccat acatttccca tacagaaaag tcgaaacaga aagagtggaa
      541 taaggtccac gtatcttttt cattaaaatc aaaaacattt ttgctgttaa acaagagacg
      601 aaccacattt ttatgttcaa gcaaagtgcc ttttggagca cctgttgtcc ccgacgtata
      661 gatcacatat gctaaattgt ttgactgtac atggttttca agattcaagc tatttttatg
      721 atagttactt tcctgatcta gattcagcac tgtgccagta aattctatat gctgcttatg
      781 gctttgcttt aataatagtt tcactcctga gtcctcaatc atgtaacgaa ttcgctcttc
      841 tggatattcc ggatcaatcg gcacatatgc cccgcccgct ttgagaatac ccagtatacc
      901 tacaatcatt tcaagagaac gttctgtcat aattccaaca agctgttcag cctctactcc
      961 ttcatttcga agtgtacggg ctagttgatt agctcgctca ttcagttcac gatatgtcaa
     1021 ttgtttatct tcaaacacaa cagctacctt atctggtaca cgttctgctt gttcttcaaa
     1081 cagttgatga attgttttgt ttcttggata ttctgctttt gtatcattaa aatctctaag
     1141 aagctgcatt cgctcctctt cgaggaccat agatagttct gatagttttg tatgcggatg
     1201 tgccaaaatg ttatctacca gatgggtaaa atgttttgtc attcgtacta tcgttgcttc
     1261 ctcatataaa gatgtcgcat attccaacat acaattcaat tgtccgttcc attcaactac
     1321 agtcaacatc aaatcaaatt tggctatctc atattcccat tcaaacggct ttatttctaa
     1381 tccttctact ttcccggctt cttgatccat attttgcaat acaaacatga catcaaagat
     1441 cgcatttctg ctcatatctc tggtgacatc taatgtctcc acaatttctt caaatggata
     1501 atcttgattt tcatatgctc ttaaggcatt ttctttcact tcactcgcaa attgctcaaa
     1561 tgttttttcc cctgttgggt agtttcgcat tgccaacgtg ttcacaaaca ttccgacaac
     1621 tcgatccaaa tcagcatgtg ggcgacctgc aattggactg cctataataa tgtcttcttg
     1681 tccgctatat ttagacaaca taagcgtgta aattgataac attaccatat atagtgtaga
     1741 acccgtttgc atagctagtt gttggagcgc ctcacttctg tgctcatcaa tcgtaaactc
     1801 aactcttgct cccttaaaat ttcgggtagc tggtctcgcg tagtcagtag gcatttgtaa
     1861 aacaggaaga tctcctccaa gcgtctctaa ccaatatgct ccttgttttc gaatctgttc
     1921 ttggttcatt tcattttgtt gccacactgc ataatcttta tattgaatac gcagttcagg
     1981 taattgggca ccctcatata attgaaataa ctcttgcatg attacagtca ttgatacgcc
     2041 atctgaaata acatgatgca tatccattag tatcatatgc tttgttgatg tgaactcaag
     2101 aacctgaact cggaaaagag gagcctgctt taaatcaaaa gcacgtataa atccctgaat
     2161 atattcatct aaatcctctg gtctcacctt tcgaacttct actttaaaat taactttatc
     2221 atgaataagc tgtttcaact caccatccaa taatttaaaa cttgtccgta aagattcatg
     2281 gcgatcaatc aattgaatgc aggcagactc cagtttagta acatctagtt ctccttcaac
     2341 caccatcaag ttgggcatgt tgtagctcaa ttctccgcct tctaattgat gcaagatata
     2401 cattcgtttt tgtgcagaag aaaccggata agattctctc tgttccacag cagggataga
     2461 tgtaaagctt tgatcttcca cagcacttat gattcttgat gataattgtt ctatcgttgg
     2521 atggttaaat atttgtcgaa cagatactct taaatttaat atcttataaa tctttgctgc
     2581 taaactagta gcttttaaag aatgtcctcc tatgtcaaag aaattatctc gtattcccac
     2641 ttgttttaag ctaagtacct ctttccaaat ctcagccagc tttaattcaa ttgatgtacg
     2701 aggtgcaaca tattttaccc cagtttgtgt atttcgatca ggcagaggga gtgccttacg
     2761 gtcaattttc ccgttagatg tcagcggcat tttctccagc tgaataaaat aagatgg
//
