LOCUS       gnlProkkaMEGCPJPM_8     2244 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MEGCPJPM_8.
ACCESSION   gnlProkkaMEGCPJPM_8
VERSION     gnlProkkaMEGCPJPM_8
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 10:27:34
            Original ID  :: gnl|Prokka|MEGCPJPM_8
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2244
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2244
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:2242]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..2242
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..2244
                     /SMILES="NC(Cc1ccccc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2244
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             2..2242
                     /NRPS_PKS="Domain: AMP-binding (9-226). E-value: 7.3e-53.
                     Score: 171.4. Matches aSDomain:
                     nrpspksdomains_ctg8_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (333-399). E-value: 4.9e-25. Score:
                     79.4. Matches aSDomain: nrpspksdomains_ctg8_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (417-702). E-value:
                     1.4e-105. Score: 344.5. Matches aSDomain:
                     nrpspksdomains_ctg8_1_Condensation_LCL.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     183.3; E-value: 1e-55)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_1"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-68, bitscore:
                     216.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.5e-18, bitscore:
                     50.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.4e-91, bitscore:
                     292.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYFKENLHMNEHDRVVQFASISFDAAVWEIFSTLFMGGSLYVPNK
                     EVVMDHLAFASYINQNKITTVTLPPSYAMYIEPEQVPCLKRLITAGSASTVALVGKWKN
                     DVTYINAYGPTEDSICSTSVIYDVNTMDLNNIPIGRPIPNHNVYILNTSDQLQPVGVPG
                     ELCISGVGLARGYLNRTDLTAEKFVDHPFIPGDKLYRTGDLARWLPEGNIEYLGRIDHQ
                     VKIRGYRIEIGEIETALLNLEAVQEAIVVAHENDNGDKALCAYYVASEAFAVSEMKEKL
                     SVQMPSYMIPSYFIQLEKMPLTSNGKIDRKALPLPDRNTQTGVKYVAPRTSIELKLAEI
                     WKEVLSLKQVGIRDNFFDIGGHSLKATSLAAKIYKILNLRVSVRQIFNHPTIEQLSSRI
                     ISAVEDQSFTSIPAVEQRESYPVSSAQKRMYILHQLEGGELSYNMPNLMVVEGELDVTK
                     LESACIQLIDRHESLRTSFKLLDGELKQLIHDKVNFKVEVRKVRPEDLDEYIQGFIRAF
                     DLKQAPLFRVQVLEFTSTKHMILMDMHHVISDGVSMTVIMQELFQLYEGAQLPELRIQY
                     KDYAVWQQNEMNQEQIRKQGAYWLETLGGDLPVLQMPTDYARPATRNFKGARVEFTIDE
                     HRSEALQQLAMQTGSTLYMVMLSIYTLMLSKYSGQEDIIIGSPIAGRPHADLDRVVGMF
                     VNTLAMRNYPTGEKTFEQFASEVKENALRAYENQDYPFEEIVETLDVTRDMSR"
     aSDomain        29..679
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_1_AMP-binding.1"
                     /evalue="7.30E-53"
                     /label="ctg8_1_AMP-binding.1"
                     /locus_tag="ctg8_1"
                     /protein_end="226"
                     /protein_start="9"
                     /score="171.4"
                     /specificity="substrate consensus: Phe"
                     /tool="antismash"
                     /translation="NEHDRVVQFASISFDAAVWEIFSTLFMGGSLYVPNKEVVMDHLAF
                     ASYINQNKITTVTLPPSYAMYIEPEQVPCLKRLITAGSASTVALVGKWKNDVTYINAYG
                     PTEDSICSTSVIYDVNTMDLNNIPIGRPIPNHNVYILNTSDQLQPVGVPGELCISGVGL
                     ARGYLNRTDLTAEKFVDHPFIPGDKLYRTGDLARWLPEGNIEYLGRIDHQVKIR"
     aSModule        29..1198
                     /complete
                     /domains="nrpspksdomains_ctg8_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg8_1_PCP.1"
                     /locus_tags="ctg8_1"
                     /monomer_pairings="Phe -> Phe"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       473..562
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0001"
                     /evalue="5.30E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg8_1"
                     /protein_end="187"
                     /protein_start="157"
                     /score="57.0"
                     /tool="antismash"
                     /translation="PVGVPGELCISGVGLARGYLNRTDLTAEKF"
     CDS_motif       644..709
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0002"
                     /evalue="6.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg8_1"
                     /protein_end="236"
                     /protein_start="214"
                     /score="37.4"
                     /tool="antismash"
                     /translation="YLGRIDHQVKIRGYRIEIGEIE"
     aSDomain        1001..1198
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_1_PCP.1"
                     /evalue="4.90E-25"
                     /label="ctg8_1_PCP.1"
                     /locus_tag="ctg8_1"
                     /protein_end="399"
                     /protein_start="333"
                     /score="79.4"
                     /tool="antismash"
                     /translation="ELKLAEIWKEVLSLKQVGIRDNFFDIGGHSLKATSLAAKIYKILN
                     LRVSVRQIFNHPTIEQLSSRI"
     aSDomain        1253..2107
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.40E-105"
                     /label="ctg8_1_Condensation_LCL.1"
                     /locus_tag="ctg8_1"
                     /protein_end="702"
                     /protein_start="417"
                     /score="344.5"
                     /tool="antismash"
                     /translation="ESYPVSSAQKRMYILHQLEGGELSYNMPNLMVVEGELDVTKLESA
                     CIQLIDRHESLRTSFKLLDGELKQLIHDKVNFKVEVRKVRPEDLDEYIQGFIRAFDLKQ
                     APLFRVQVLEFTSTKHMILMDMHHVISDGVSMTVIMQELFQLYEGAQLPELRIQYKDYA
                     VWQQNEMNQEQIRKQGAYWLETLGGDLPVLQMPTDYARPATRNFKGARVEFTIDEHRSE
                     ALQQLAMQTGSTLYMVMLSIYTLMLSKYSGQEDIIIGSPIAGRPHADLDRVVGMFVNTL
                     AMRN"
     CDS_motif       1322..1432
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0003"
                     /evalue="1.50E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg8_1"
                     /protein_end="477"
                     /protein_start="440"
                     /score="39.9"
                     /tool="antismash"
                     /translation="SYNMPNLMVVEGELDVTKLESACIQLIDRHESLRTSF"
     CDS_motif       1628..1693
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0004"
                     /evalue="4.60E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg8_1"
                     /protein_end="564"
                     /protein_start="542"
                     /score="31.9"
                     /tool="antismash"
                     /translation="MHHVISDGVSMTVIMQELFQLY"
     CDS_motif       1724..1759
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0005"
                     /evalue="1.40E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg8_1"
                     /protein_end="586"
                     /protein_start="574"
                     /score="17.5"
                     /tool="antismash"
                     /translation="QYKDYAVWQQNE"
     CDS_motif       2015..2104
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0006"
                     /evalue="2.60E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg8_1"
                     /protein_end="701"
                     /protein_start="671"
                     /score="51.9"
                     /tool="antismash"
                     /translation="DIIIGSPIAGRPHADLDRVVGMFVNTLAMR"
     CDS_motif       2153..2242
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0007"
                     /evalue="3.30E-12"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg8_1"
                     /protein_end="747"
                     /protein_start="717"
                     /score="38.7"
                     /tool="antismash"
                     /translation="KENALRAYENQDYPFEEIVETLDVTRDMSR"
ORIGIN
        1 aacatacttt aaagaaaact tgcatatgaa cgagcatgac cgagttgtac agtttgcgag
       61 tatctcattt gatgcggctg tttgggaaat tttctcgaca ctgtttatgg gaggctcatt
      121 atacgtgcca aataaagaag ttgtcatgga tcatttggca tttgcatcgt atattaacca
      181 aaataaaatt acaacggtga cgctacctcc gagctatgct atgtatatag agcctgaaca
      241 agttccttgt ttgaaaaggc tgattacagc aggatcagct tcgacggtag cattagtggg
      301 aaaatggaaa aatgatgtaa catacatcaa tgcatatggt cctaccgaag attctatttg
      361 ttcaaccagt gtgatttatg atgtcaacac aatggatttg aataatatac caattggccg
      421 tcccattcct aatcataatg tatatatatt aaacaccagt gatcaattac agcctgtagg
      481 agtcccagga gaattatgta tcagtggagt tggtctagct cgaggctact taaaccgaac
      541 ggatttaacg gccgaaaagt ttgttgacca tccgtttatc cctggtgata aattgtatcg
      601 aactggagac cttgccagat ggttaccgga aggtaacatt gagtatttag gacggattga
      661 ccatcaagtg aaaatacgcg gataccggat tgaaattgga gaaattgaaa cagctttatt
      721 gaatctagaa gctgtacaag aagcaatcgt ggttgcgcat gaaaacgaca atggagataa
      781 agcgttatgt gcatactacg ttgcgagtga agctttcgcg gtcagtgaga tgaaagagaa
      841 attatctgtc caaatgccaa gctacatgat cccatcttat tttattcagc tggagaaaat
      901 gccgctgaca tctaacggga aaattgaccg taaggcactc cctctgcctg atcgaaatac
      961 acaaactggg gtaaaatatg ttgcacctcg tacatcaatt gaattaaagc tggctgagat
     1021 ttggaaagag gtacttagct taaaacaagt gggaatacga gataatttct ttgacatagg
     1081 aggacattct ttaaaagcta ctagtttagc agcaaagatt tataagatat taaatttaag
     1141 agtatctgtt cgacaaatat ttaaccatcc aacgatagaa caattatcat caagaatcat
     1201 aagtgctgtg gaagatcaaa gctttacatc tatccctgct gtggaacaga gagaatctta
     1261 tccggtttct tctgcacaaa aacgaatgta tatcttgcat caattagaag gcggagaatt
     1321 gagctacaac atgcccaact tgatggtggt tgaaggagaa ctagatgtta ctaaactgga
     1381 gtctgcctgc attcaattga ttgatcgcca tgaatcttta cggacaagtt ttaaattatt
     1441 ggatggtgag ttgaaacagc ttattcatga taaagttaat tttaaagtag aagttcgaaa
     1501 ggtgagacca gaggatttag atgaatatat tcagggattt atacgtgctt ttgatttaaa
     1561 gcaggctcct cttttccgag ttcaggttct tgagttcaca tcaacaaagc atatgatact
     1621 aatggatatg catcatgtta tttcagatgg cgtatcaatg actgtaatca tgcaagagtt
     1681 atttcaatta tatgagggtg cccaattacc tgaactgcgt attcaatata aagattatgc
     1741 agtgtggcaa caaaatgaaa tgaaccaaga acagattcga aaacaaggag catattggtt
     1801 agagacgctt ggaggagatc ttcctgtttt acaaatgcct actgactacg cgagaccagc
     1861 tacccgaaat tttaagggag caagagttga gtttacgatt gatgagcaca gaagtgaggc
     1921 gctccaacaa ctagctatgc aaacgggttc tacactatat atggtaatgt tatcaattta
     1981 cacgcttatg ttgtctaaat atagcggaca agaagacatt attataggca gtccaattgc
     2041 aggtcgccca catgctgatt tggatcgagt tgtcggaatg tttgtgaaca cgttggcaat
     2101 gcgaaactac ccaacagggg aaaaaacatt tgagcaattt gcgagtgaag tgaaagaaaa
     2161 tgccttaaga gcatatgaaa atcaagatta tccatttgaa gaaattgtgg agacattaga
     2221 tgtcaccaga gatatgagca gaaa
//
