LOCUS       gnlProkkaNNKFPLML_14    2564 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NNKFPLML_14.
ACCESSION   gnlProkkaNNKFPLML_14
VERSION     gnlProkkaNNKFPLML_14
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 10:40:56
            Original ID  :: gnl|Prokka|NNKFPLML_14
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2564
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2564
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:2564]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..2564
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..2564
                     /SMILES="NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2564
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(3..2564)
                     /NRPS_PKS="Domain: AMP-binding (1-352). E-value: 4.7e-96.
                     Score: 313.7. Matches aSDomain:
                     nrpspksdomains_ctg14_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (454-523). E-value: 7e-26. Score:
                     82.1. Matches aSDomain: nrpspksdomains_ctg14_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (537-825). E-value:
                     6.7e-111. Score: 361.9. Matches aSDomain:
                     nrpspksdomains_ctg14_1_Condensation_LCL.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     317.1; E-value: 2.8e-96)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-114, bitscore:
                     369.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.6e-18, bitscore:
                     51.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 8.8e-103, bitscore:
                     329.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGAS
                     LLLTQPGCSAPNFSGETLEVDMTSLASEKAENHLFTPADGGSLAYVIYTSGSTGQPKGV
                     AVEHRQAVSFLTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWWALSGASAYLLPPGWE
                     KDSALIVKAIHQEKVTTAHFIPAMLNSFLDQAEMLALGDGTNLKRVFAGGEPLAPRTAA
                     RFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLA
                     VQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNIE
                     FLGRLDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPELCAYVEGLQRNEV
                     RAQLESLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYTAPRNVTEMKL
                     SQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVFAHPTVEGLA
                     TVIRKGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNP
                     ERMDRAFKELIKRHESLRTSFEQDAGGDPVQRIHDEVPFTLQTTVLGERTEQEAAAAFI
                     KPFDLSQAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIREFGELYNNRKLPALR
                     IQYKDYAVWQEGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGDKVSFT
                     LEPEVASGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPIL
                     GMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFE"
     aSDomain        complement(90..953)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg14_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.70E-111"
                     /label="ctg14_1_Condensation_LCL.1"
                     /locus_tag="ctg14_1"
                     /protein_end="825"
                     /protein_start="537"
                     /score="361.9"
                     /tool="antismash"
                     /translation="ETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMDRA
                     FKELIKRHESLRTSFEQDAGGDPVQRIHDEVPFTLQTTVLGERTEQEAAAAFIKPFDLS
                     QAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIREFGELYNNRKLPALRIQYKDY
                     AVWQEGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGDKVSFTLEPEVA
                     SGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFVNT
                     LALRTRP"
     CDS_motif       complement(99..188)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_1_0008"
                     /evalue="9.00E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg14_1"
                     /protein_end="822"
                     /protein_start="792"
                     /score="50.2"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHKDLEPILGMFVNTLALR"
     CDS_motif       complement(450..479)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_1_0007"
                     /evalue="7.50E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg14_1"
                     /protein_end="705"
                     /protein_start="695"
                     /score="15.3"
                     /tool="antismash"
                     /translation="QYKDYAVWQE"
     CDS_motif       complement(510..575)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_1_0006"
                     /evalue="3.00E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg14_1"
                     /protein_end="685"
                     /protein_start="663"
                     /score="32.6"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNILIREFGELY"
     CDS_motif       complement(774..881)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_1_0005"
                     /evalue="4.10E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg14_1"
                     /protein_end="597"
                     /protein_start="561"
                     /score="54.6"
                     /tool="antismash"
                     /translation="YNMPAVLELEGKLNPERMDRAFKELIKRHESLRTSF"
     aSDomain        complement(996..1202)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg14_1_PCP.1"
                     /evalue="7.00E-26"
                     /label="ctg14_1_PCP.1"
                     /locus_tag="ctg14_1"
                     /protein_end="523"
                     /protein_start="454"
                     /score="82.1"
                     /tool="antismash"
                     /translation="EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFD
                     VQVPLKDVFAHPTVEGLATVIRKG"
     aSModule        complement(996..2561)
                     /complete
                     /domains="nrpspksdomains_ctg14_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg14_1_PCP.1"
                     /locus_tags="ctg14_1"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1479..1544)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_1_0004"
                     /evalue="4.30E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg14_1"
                     /protein_end="362"
                     /protein_start="340"
                     /score="41.0"
                     /tool="antismash"
                     /translation="FLGRLDDQVKIRGYRIEPGEIE"
     aSDomain        complement(1509..2561)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg14_1_AMP-binding.1"
                     /evalue="4.70E-96"
                     /label="ctg14_1_AMP-binding.1"
                     /locus_tag="ctg14_1"
                     /protein_end="352"
                     /protein_start="1"
                     /score="313.7"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="LSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASL
                     LLTQPGCSAPNFSGETLEVDMTSLASEKAENHLFTPADGGSLAYVIYTSGSTGQPKGVA
                     VEHRQAVSFLTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWWALSGASAYLLPPGWEK
                     DSALIVKAIHQEKVTTAHFIPAMLNSFLDQAEMLALGDGTNLKRVFAGGEPLAPRTAAR
                     FASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAV
                     QPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNIEF
                     LGRLDDQVKIR"
     CDS_motif       complement(1626..1715)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_1_0003"
                     /evalue="5.00E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg14_1"
                     /protein_end="313"
                     /protein_start="283"
                     /score="57.1"
                     /tool="antismash"
                     /translation="PSGVAGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       complement(2241..2300)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_1_0002"
                     /evalue="3.50E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg14_1"
                     /protein_end="108"
                     /protein_start="88"
                     /score="34.8"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVEH"
     CDS_motif       complement(2484..2525)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_1_0001"
                     /evalue="5.20E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg14_1"
                     /protein_end="27"
                     /protein_start="13"
                     /score="19.5"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
ORIGIN
        1 tcttcgaacg ggtaatcctg gtgctcaaag gcttccaatg ctgtctcacg cacttcctgc
       61 aaatactgta cgaatggctt cccgccctcc gggcgcgtcc gaagcgccag cgtgttcaca
      121 aacatgccga gtatcggctc aagatccttg tgcggccggc cggcaattgg cgagccgacg
      181 atgatatctt cctgtccgct taagcgtgac aagaacgcgg tgtaagccgc aaggagcacc
      241 atgtacagtg tgcttccgtt ttctcgtgcc agcttgtgaa ggcctgatgc aacctctggt
      301 tccagcgtaa atgagacctt gtcacccgcg aagcttcgca ccggcgggcg ggcatgatca
      361 gccggaagat ccagcacagg cagctcgccc tcgagctgct tcagccagta cgcctcctgc
      421 gttttgtacg catctcctgt tttaaatcct tcttgccata cggcataatc tttatattga
      481 atgcgcagtg ccggaagctt ccgattattg tacagctcgc cgaattcccg aatcagaatg
      541 ttgacggaaa caccgtctga aatgatgtga tgcatatcca ccagcaacag gtgccgctca
      601 tctgatacct ttacgatttg ggcacggaac agcggcgctt ggctgagatc aaacggtttg
      661 ataaaggcgg ctgcggcctc ctgttcggtt cgttcgccga gaactgtagt ctgtaacgta
      721 aacggcacct cgtcatggat gcgctgcacc ggatcgcctc ctgcgtcctg ttcgaaggag
      781 gtacgaagcg actcgtggcg cttgatcagc tctttgaaag ctctgtccat cctttcaggg
      841 ttgagcttcc cttcgagctc taacacagct ggcatattgt agcctgtccc tccgtcctcc
      901 agctgctgaa ggacataaat ccgcttttgg gcagaggaaa ccggatacgt ttcctgtttt
      961 tcagcgggct taatcgcttc atatggactg tccgttcctt tacggataac ggtagccagt
     1021 ccttctaccg tcggatgggc aaacacatct tttagcggca cctgtacatc gaattctttg
     1081 gcaatccgtg agacaagcgc cgttgctttt aaggaatgtc ccccgcggtc aaaaaagttg
     1141 tcgtgaatcc cgacagggcc atttttcagc acgtcctccc atagctgaga aagcttcatc
     1201 tcagtcacgt ttctcggcgc cgtgtaggtc tccgcatctg ccgctccgcc aggagctggc
     1261 agggcgtttc ggtcgagctt tccgcttggt gtaaccggcc actgttccat ttctatcata
     1321 taggctggga ccatgtagcc cggcaacagg ctctcaagct gcgctcggac ttcgtttctt
     1381 tggagccctt ctacataagc gcataattcc ggctcgccgc tgtctgtccg tacggtaacg
     1441 gccgcctctc ttacaccttc tatacttctt agtgccgctt caatttctcc cggttcaatc
     1501 cggtagccgc gaattttcac ctgatcatcc aaccgtccca ggaattcaat attcccgtca
     1561 gggagccagc gcgccacatc tcctgttttg tacatacgtt cacccgggta aaacgggtct
     1621 tctagaaaac gctcctccgt taatgccggc cgattcaaat aacctctggc aacacccgct
     1681 ccggcaatgt atagttcgcc ggcgacaccg gaaggctgta cggctaaatg cggatctaaa
     1741 acatacaaac gcgcaccagg tacgggcttc ccaatcggaa tccgcaaacg gtctctgtcc
     1801 cgttctggat ccaatacgta aaatgccgcg tctaccgttg cttctgtcgg cccgtagcca
     1861 tggattaatg atacctgcgg caatacagaa gcaaaacggg ctgccgtacg cggcgcaagc
     1921 ggttcacctc cggcgaatac acgctttagg tttgtcccgt caccaagcgc taacatttct
     1981 gcttgatcca gaaagctgtt cagcatagcc ggaataaaat gagccgttgt cactttttcc
     2041 tgatgaatgg cttttacgat caatgcggag tctttttccc agccgggcgg aagcagatac
     2101 gccgaagcac cggaaagagc ccaccaaaac agctgccaca cagacgcatc aaaggaaaaa
     2161 gaggttttca ccatgacaat gtcatcttct gaaagcggaa actggtgctg catgccggtc
     2221 agaaaggaaa cagcctgacg gtgctcaacg gccactcctt tcggctgccc ggtagagccc
     2281 gatgtataga tgacataggc gagagaaccg ccgtcagcag gagtaaacag atggttttct
     2341 gctttttcgc tcgcaagaga tgtcatgtcc acttcaagcg tctctccgga aaagttcggt
     2401 gcggagcatc ccggctgtgt cagcaagagc gatgccccgc tgtctttcag catgtagctc
     2461 agccgctcct ttggatacgc aggatcaagc ggcaaatacg cccctccggc cttcaataca
     2521 gcaaggacag cgatcagcat gtcaggtgag cgttcagaca ggat
//
