LOCUS       c00014_gnlPro..        17103 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EEMKBJPC_14.
ACCESSION   c00014_gnlPro..
VERSION     c00014_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 12:25:11
            Original ID  :: gnl|Prokka|EEMKBJPC_14
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17103
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17103
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4567:7103]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4568..7103
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..17103
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17103
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(556..1218)
                     /locus_tag="ctg14_1"
                     /transl_table=11
                     /translation="MKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTSQENEPGTLFM
                     QTSHNEETTNFVVECYQNEASYDTHANSKQFKDFTDVAKDILTSRVKVELFPEFISTKA
                     EKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAMIAGTVADQPN
                     EWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVDQGAIFYQP"
     CDS             complement(1314..1853)
                     /locus_tag="ctg14_2"
                     /transl_table=11
                     /translation="MLKRTLLSLTSMVLVLGLTGLASQVETVDASTYGNGVQVTIPKKM
                     QGTWYSYDRNAHNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWM
                     SGKTTKMKNDTFYEIDPWITFENWSLYRVVSQTINGKKHNVLVYSSRYDGGNYFRSKKL
                     AKKMKDYKFKKVNYTL"
     CDS             complement(1952..2569)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_3"
                     /sec_met_domain="LysR_substrate (E-value: 3.9e-13,
                     bitscore: 42.3, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNKMTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHD
                     GAFAKLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDM
                     TCFIVAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASGSGYFILNENTVRLIN
                     TADLQPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             complement(2559..2720)
                     /locus_tag="ctg14_4"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             complement(2736..3902)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_5"
                     /sec_met_domain="Acetyltransf_10 (E-value: 3.2e-07,
                     bitscore: 23.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKKNKNNLKQITALIQYAFLKNNDLTKDENFMSRYDHSTGYGY
                     FDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGQGHISQLMKEILHELHRQD
                     IPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIVRGKWDNLAVQNG
                     VIQLYERQLHTNDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERPISYLIYRIRDNT
                     FLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPEQNELQVDLRPYM
                     MSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRKVAVERKEDALVD
                     FSGSITAWTQVLLGRLTMNAAVKLGLITDYRIQKLDFVKGDVSFYDYF"
     CDS             complement(4018..4554)
                     /locus_tag="ctg14_6"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDIKMNI
                     PGPIKNNRYLTKMFMFGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFEDQTSLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPAKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             complement(4568..5470)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_7"
                     /sec_met_domain="OTCace (E-value: 1.9e-48, bitscore: 157.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 2.1e-20, bitscore:
                     66.4, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGDGRDNVADSLLVCGSMLGVNVHIVTPKPLFTHPDVQKIAQNFA
                     QDSGSKNLITDDIAQGVKGANVVYTDVWVSMGENDWSERIKLLKPYTVTMKMMQMTGTP
                     DDQLIFMHCLPAFHDRTTQVGEEIYEKYGLNEMEVTDEVFNSKYAWQFTEAENRLHSIK
                     AVMAATLGNLFIPIACGGGGIPVIVKDGHLRGVAGVIDKDFSAAKMAEDINADELVILT
                     TVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGSMKPKIEAAIEFVEKTGNLAII
                     TSLSNANKLADGVGTIVYN"
     CDS             complement(5431..5862)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_8"
                     /sec_met_domain="OTCace_N (E-value: 8.3e-37, bitscore:
                     119.6, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFASHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTQSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVMAAIMLPTVF"
     CDS             complement(5873..6799)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_9"
                     /sec_met_domain="Amidinotransf (E-value: 2.1e-84, bitscore:
                     276.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LHQLLLNYLQELPTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPD
                     YPFYLDPMPNVYFTRDQQAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPV
                     WRDRYHHGRLEGGDELVLNNHVLAVGISQRTSATAITDLAHNLFGHSSYDTILAIKISH
                     NHAMMHLDTVFTMINYDQFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKE
                     NLHLSELDLIPTGGGDPIDAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGIIV
                     HEIRSSELSRGRGGPRCMSCPLIREDL"
     CDS             complement(6894..7103)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_10"
                     /sec_met_domain="Amidinotransf (E-value: 6.9e-13, bitscore:
                     41.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGDQSIIS"
     CDS             complement(7177..8025)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     78.7; E-value: 8.2e-25)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg14_11"
                     /sec_met_domain="LysR_substrate (E-value: 3.7e-29,
                     bitscore: 94.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.8e-24, bitscore: 78.7,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDAGQIFQSYANEIIFLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQQKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIAA
                     I"
     CDS             8154..10427
                     /locus_tag="ctg14_12"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGEVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(10495..10809)
                     /locus_tag="ctg14_13"
                     /transl_table=11
                     /translation="MKRCKNWVVTIVALLMLVGEISVLPANLQGSTSVVNAAIHHRRRK
                     HQYRDKTKIYTGNYRIVGNKRSKIFHVMRGHNYRMNRENAVFFKSKAAARAAGYRESKR
                     "
     CDS             complement(10897..11166)
                     /locus_tag="ctg14_14"
                     /transl_table=11
                     /translation="MAILGTITKKDLSRIGSYASAALIGLIVAMLVNLFLHNPIIDYVF
                     SIIAVIIFTILTAWDAQRMKDIYLQYGDDLSTNGLAVLGANEDK"
     CDS             complement(11345..11440)
                     /locus_tag="ctg14_15"
                     /transl_table=11
                     /translation="MDNFDQESGQQQYANDSGLNVFLAKYMVIWP"
     CDS             11614..11967
                     /locus_tag="ctg14_16"
                     /transl_table=11
                     /translation="MTMRSLGLSIYPGHSKFEGNAHYLDLAHKYGFSRIFMSMLEVQGS
                     PEGTKAKYKKIIEYGNKLGFQTFLDVNPAIFKQLGVSYDDLKFLPILVQQASVLTQHLM
                     VQLKQCFLTTHMV"
     CDS             11940..12707
                     /locus_tag="ctg14_17"
                     /transl_table=11
                     /translation="MLSYNPYGLIIELNMSNNVDYLNNIISYQANTPFIYGCHNFYPQR
                     GTGLPYDFFIACSERFKKFGFHSAAFVSSQVGQMGPWNVEDGLPTLEQDRNLPIDVQAM
                     HLWASGLIDDVIIGNAYASEAELKALSEVNRYQLMLHVNYVNDVNKIEKTIVEAPQHFR
                     RGDITKDVIRSTMPRVTYADIPNPVHDNNVEFQRGDIIIGNDNFGHYKNELQIVLEPHK
                     ESRMNKVGSIRSDELFLLDFIKPWSKFKLIGNK"
     CDS             complement(12751..14070)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_18"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.2e-59, bitscore:
                     192.5, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 9.7e-27, bitscore:
                     86.6, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNVKNIIIGFGKGGKTLAKFLAQKGEEVLVVEKSDKMYGGTCIN
                     IACLPSKRLIIEAGNGVDFVDAVNGKNDMTSMLRNKNYHMLADEENVTVLDGTTKFMNN
                     HEIAVTTVNDQIEEFHGDRIFINTGALPVMLPIPGLMESNAILDSTAAMDQTNLPKKLV
                     IIGAGYIGLEFASMFAEYGSEVTVLDLHDNFLPREDDDIAVEIKHDLENSGVKFELGVK
                     ISRIDDHTVYYEKDGVTTTTVADRILVATGRKPNTEDLGIENTDIELNDRGTIMVDDYL
                     RTNVENVWAIGDVKGGPQFTYISLDDFRIIKDQLYGDAQRRVSDRINVPYSVFITPTLS
                     RVGLNEKEAKSQNIKYELKKLPVTAIPKAQVLKDPRGLFKALINPANNQILGVTLYGAE
                     SYELINQISMAMKMKIPANILRDQIYTHPTMSESFNDLFK"
     CDS             complement(14523..15050)
                     /locus_tag="ctg14_19"
                     /transl_table=11
                     /translation="MAVDFSKYIASVQDFPNKGIVFRDITPILQDGELYRAATHELAEY
                     AKSKKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEYGSNSLE
                     MHKDAIKPGQRVVVCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLHGRDKLPD
                     VDIYSLVQYHGA"
ORIGIN
        1 gcttctaatg tgtttttgtt cttaacatca gactactggt ctttttgttt tagctcaagt
       61 ccaaattcaa aggacttgag ctttttaatt atttattcaa cttaccgcaa aaaattatac
      121 acttagcaag catattctct attttttaac caaaacaagc agcatcccat cgatactgct
      181 ttattttatg cgcagttgca ctagactttg actctatttc tattttacgt gctaaccagc
      241 cttttttcta gttttatttt cttaactaat ccattaggtt ttacatataa attcttaata
      301 ttatttcgct attataagat caattaagat gaaaggaatg agaaccttga ttaaactact
      361 cttaattggt ggatcatttt taacgcttgg tttaatggcc atcagctcag tattaattaa
      421 taaaccagca gtagcaaagg taaaacatcg ccactaaaaa ccagaataat atatattaat
      481 aaatcttttt cccctctaac tagaaagacc aggttatgta ctccacatag cctggtcttc
      541 ttttcgtctt attctttatg gttggtagaa aattgcacct tggtcaacaa ttacatctgg
      601 ttgcaactta cgtaaactct tactttcaac acaatatttt gtattattca aatactcttt
      661 gaagttctta gtttccaagt gctgcttgta agcttcatta ttacgataaa cttcaatagc
      721 taaccattca tttggttgat cggcaacagt tcctgcaatc attgccaaaa tatctttttc
      781 ttcttcgact gccgttttca tttctttcat tacagcatga gcaaactcat cgcccttacc
      841 taaagaaaca ccaatttcag ttagataaat aacataatca tttgatccgg taactgctag
      901 tttttctgcc tttgtagaaa taaattccgg aaacaattct acctttactc gactagttaa
      961 aatatcttta gcaacgtcag taaaatcctt aaattgcttt gaattagcat gagtatcata
     1021 acttgcttcg ttttgatagc attctactac aaaattagta gtttcttcgt tatgacttgt
     1081 ctgcataaac aatgtgcctg gttcgttttc ttgagaagta agcatattat gttgccctgc
     1141 cttaacgaac tttgcatgat cctctttatt agtttctagt ttatataaac gcaaaattgg
     1201 tgtttgtttt aatttcataa tttctcctcc aagaattaat tttgtcacta ttatactgaa
     1261 ttttaccgcg tctattagta aaaaacatcc cttagttaag ggatgtcaca aaactataac
     1321 gtgtaattaa ctttcttaaa cttgtagtcc ttcatttttt tagctaattt cttgcttctg
     1381 aagtagttac caccatcata tctactagaa taaaccagca cgttatgctt tttaccatta
     1441 atggtttgtg ataccactcg ataaagactc caattttcaa aagtaatcca cggatcaatc
     1501 tcatagaatg tatcattctt cattttggta gttttaccag acatccagtt ttgcgttacc
     1561 ttatcaaagt tcttctggtt agcaattcta ccattgaagt aatcactaat tgtcgaagcc
     1621 tcctgggtaa atattggttt gccattaaca gtatgttcag taaaggtgat ctttgtgcca
     1681 ttatgtgcat tacgatcata agagtaccaa gtaccctgca tcttttttgg aatagtaacc
     1741 tgtacaccat taccataagt tgaagcatca acagtctcaa cttgactagc caaaccagtt
     1801 aatcctaaaa caagtaccat tgatgttaaa gataacaaag ttctttttag cataaaaatc
     1861 atctccagca tataaaatat atgaatccgc tttcataata tattttacag tatcttatag
     1921 tacttagaca agatattttt aactttacag attaatattc ttgctgcaat agctttataa
     1981 actcactact taacgctgaa tttgacttat aaaaagccat tatcttttgc tttattaact
     2041 gaccatgatc aagcaagaaa agtggctgca aatctgcagt attaattaac ctaaccgtat
     2101 tctcatttaa aataaaatag ccagacccag aggcgaccaa cagtgctgct tcttcaaccg
     2161 agttagaagc gatgaattga ctgccaattt gatacaaatc tttaaataaa tgtagctcac
     2221 taacctcttc ttcaggttta gccacaataa aacaagtcat atcattgagc tcgtcttttt
     2281 caatcatttg aatgccatta ggatacattc ccttgggcaa aattgccatt acaccagctt
     2341 gagtcaattc tgtttcatca aagttaagat tctcgtcacg caaatcattg attgctatgt
     2401 ctgcttcatc ttcattcaat tttgcaaaag caccatcatg actagtcgca agtagtttta
     2461 catctacatt aggatgtttt aacacaaaat gctgcactgc ctgatctaat tccttacgac
     2521 ctaattggtc aaaatatgca atctttaatt ccgtcatttt atttttcatc cagcggtgcg
     2581 tgtccttctt ctgctactct tcttttatcc ttagtatctt catgcttatt aagtgccatc
     2641 aaggcaaaaa agatcaaatt caaaccacta actacaatgc caaataattt tattaaattg
     2701 agtttctttt ctttgctcat tttttaacct cacaactaaa aataatcata aaatgataca
     2761 tcgcctttaa cgaaatctaa tttttggatg cggtaatctg taattaatcc tagtttaaca
     2821 gcagcattca tggttagtct acctaatagt acctgggtcc acgcggtaat tgatcccgaa
     2881 aaatcaacca atgcatcttc cttacgttct accgctacct tacgtccatg attacttaat
     2941 tgccaaactc caatattcca aggacactgt tcatcgctat tgacttccag attaaaatca
     3001 ccttcttgca ttggccgcat acaagccaaa actttttcaa aatcaataat tcgactcatc
     3061 atataaggac gcaaatcaac ttggagttcg ttttgttcag gaaaaagttc agctcgtaac
     3121 gatttctctg gtacgctcat tttaaattgc ttaacactgc ccgcgtgcga acccataaaa
     3181 ccaaacatac tcagtaatcc ctgcggcgta attgcgtaca tttcatcagc taaaaaagta
     3241 ttatctctaa tgcgataaat caagtaacta attggccgct catccgcgtc aaaataaacg
     3301 gctacattgc ggtgatgata ataagaatca agtctattcc accaccatgc ctcacgtaca
     3361 accgtgttac gttcatcatt agtatgcagt tgacgttcat aaagttgaat cacaccattt
     3421 tgaacagcta aattgtccca cttgccacgc actatatgac cagaacgtgg taatttaaaa
     3481 ctacgcaatg cgcttccatc aaagcgatat tctttttgat aaatactatt gctaaacccg
     3541 tactggcgat aaaagctctc cgaaaatggt gccaggttag caaacggaat atcttgccta
     3601 tgtaattcat gcaaaatttc tttcattaat tgggaaatat gaccttggcc acgatactca
     3661 ggatatgaag ctacataacc tattccagcc atcggtaaat gatgcccaaa aacatcactt
     3721 ttaaatcgat taaccataat atagctagct aatttttcct tatcaaaata gccataacct
     3781 gtactatgat cataacgact cataaaattt tcatctttag tcaaatcatt atttttcaaa
     3841 aatgcatatt gaattaatgc cgtaatttgc tttaaattat tcttattttt ctttaatttc
     3901 atgcttattc ctatacgtac atctataaat ttattcatta ctattttagt tcattttttt
     3961 aatttttaac tagatttttc ataaaaataa accggaatca taaaatcccg gtttatttta
     4021 cgcaacgtat tcttgataaa gctgagagat aaatgcctgc atctgttcca ctgaatgtct
     4081 ccggctgcga gcacattctt tagcagggcg atcacataaa aagcacttac gtggctgcct
     4141 gcccaaatct ctgcgtgaaa ttgcagcttg tttatttttt accaacacgt ctgcatcaaa
     4201 gagacgtccc aatgatgtct gatcttcaaa atcaattgtt gagcgcttta ctttttcaat
     4261 tgacaaagat aatacataga agttttcaca gccactatca tcattaagct gtgtcaccaa
     4321 tttaaaatga taacctaggt tagtccaagc attttccagc tcattgatac caaacataaa
     4381 cattttagtt aaatagcgat tattcttgat tggtcctggg atattcatct taatgtcgac
     4441 tagagtttga ttaggatact tattaaaaat cttatgttgt acagctactc gcctatcttt
     4501 agctgctaaa acttgggcaa tatcctgctt ttttccttca ttaaaaatat tcatttttat
     4561 cacccagtta attataaacg attgtgccga ctccgtctgc tagtttgttg gcattgctca
     4621 aagaggtgat aattgctaaa ttacctgttt tttctacaaa ttcaattgca gcttctatct
     4681 taggcttcat actcccagct gcgaaataac ctgctgctag atattgtttg agctgttcaa
     4741 cttttatttt accaattgct tgttgatttt ctttgccata attcaaaaat gcatgatcca
     4801 ccgttgttag aattactaat tcatcagcgt tgatatcttc tgccatttta gcagcggaaa
     4861 aatctttatc aattacgccg gcaacacctc tgagatgccc atctttcaca ataacaggga
     4921 tgccaccacc gccacaggca atcggaataa ataaatttcc taaagtagcc gccatcactg
     4981 ctttaattga atgcaatcga ttttcagctt ctgtaaattg ccaagcatac tttgaattaa
     5041 agacctcatc agttacttcc atctcattta agccatattt ttcatagatt tcttctccca
     5101 cctgagttgt tcgatcatga aaagctggca aacaatgcat aaagatcaat tggtcatctg
     5161 gtgtaccagt catttgcatc attttcattg tgaccgtata tggctttaat aatttaattc
     5221 gttcagacca atcattttca cccatcgaaa cccaaacatc ggtataaaca acattggctc
     5281 ctttaacgcc ctgagcaata tcatctgtga tcaaattttt tgaacctgaa tcttgggcaa
     5341 aattttgagc aattttttgt acatcaggat gtgtaaacaa aggcttgggt gtaacaatat
     5401 gtacattaac acctaacatt gagccacaaa ctaaaagact gtcggcaaca ttatcgcggc
     5461 catcacccac ttccaaacag gaacgccaga atatttagcc agctcttcta catcttcttg
     5521 agcaaaaccg cgatattcaa ttccatcata cattgagcct aggactttag ccgtatcctt
     5581 gacgctttct tttttaccta agtggatctc gcttgcgcct agatattctg gatgagcacc
     5641 taaatcatta caagctacta caaaagcaga ttgcgtccta gttgaggctt tttcaaaaag
     5701 tagtgcaata tttttacctt tcagatattc atgtgggata tgctcttttt taagttcttt
     5761 taaatgtgat gcaaaatcaa ttaaatatga aatttcagct ggagtatagt ctttacaatc
     5821 gagaaaactt ctaccttgaa aaacattttg taaatatttc attttttgcc tcttataaat
     5881 cttcacgaat caacggacac gacatacatc taggaccgcc acgaccacgt gagagttcac
     5941 tagaccgaat ctcatgaacg atgatgccat gttttcttag caaatcatta gatacataat
     6001 tacgatcata agtaacgact tcacctggtg caattgccaa ggtatttgag ccgtcattcc
     6061 attgctcacg tggtgcgtca attggatcac caccgccagt tggaattaaa tccaattcgc
     6121 ttaaatgcaa gttttctttc aaaacctgca ccaaatcatt cttttctgta atttttacac
     6181 cgttgtgatc atcgggctgt agaacataaa tatcaatttt gccggcttta tctaaaataa
     6241 agggatgaac cgtaaattga tcataattaa tcattgtaaa aactgtatca aggtgcatca
     6301 tagcatgatt gtgcgaaatc ttaatcgcta aaatcgtatc ataacttgaa tgaccaaata
     6361 aattatgagc taagtcagta attgcagttg cagaagtgcg ttgtgaaata cctacagcta
     6421 acacatggtt atttagaact agttcatccc cgccctcaag gcgaccatga tgataacggt
     6481 cacgccaaac tggaatagtt gcgttcttga aatcaggatg atttttcaaa attgtttcca
     6541 taaataatga ttcacgtcgt ctagctctga aagtcatccg gttaatggtc atccctgaac
     6601 caattgcagc ctgttgatct cgagtaaaat atacatttgg cattggatca agataaaaag
     6661 ggtaatctgg gtcctcagcc aaatctgcta aagatggggt agaattatga atcgcacttt
     6721 ttctaattcc agcaatcacc gtttttacca tttccttagt tggcaattct tggagatagt
     6781 tcagcaataa ttgatgcaaa ggatcctgtt ttttaatact tgattcatcc agtaactgat
     6841 ctaagaatgc ccgacgaact ttctcatctg ttaaagattc tgctaataaa tcctcaagat
     6901 ataatacttt gatccccctg ctgcctcaat acatgcgcaa aagcatcatg ttcttcttgg
     6961 gcaatcttca gataaggaat atcgtcaatt aacattcgat gcaaaatatc tggggctaga
     7021 ttttctagtt cttttcccgg tcgatgtaac atcaccgttt ttaacttacc aatttctgaa
     7081 taaacatgaa tcggactgga cattcaacca ccttctatta attattgtat tcgtttacat
     7141 ttattatgga tcaattaggc aaaagttaca gtattatcat attgcagcaa tgattttttt
     7201 cattaaaggt gtaacttgat gatctttacg ccaaaccagc tgcaaatgtg ttatccaatt
     7261 agcatgttta attgcgatca tattttcttg ggcataagtt gtcgcaattg attctggtac
     7321 tagcgctact cccatttttc tcttggccca agtaattgct gtccgtgaat catcacactt
     7381 aaccgcataa aatggcttaa gcccatgatg tgcaaaagtt tgattaaaaa tatcctcaaa
     7441 gcggcgataa ataatcaatg gctgatctgc tagatcttta atgcgtaatt cttttttttg
     7501 ctgaaaatct gggtctacac taatagccat cattttttca gttgttaaag tcttagtatt
     7561 taaacctgtc tggttgtaag gcgttcgtac aatgcctaga tcgattgtct ttttttctaa
     7621 tttatccagg atgccataag tattatcttc ataaatatca aaagaaattt ccggataata
     7681 ttttcgtaat tcattaaaag aattcattgg tatcaagccc gttgaggaag atgccattcc
     7741 aattgcaatc gttcccaatt caccggaaat agtcttatgt acttggtttt cagcattttg
     7801 agctagaaaa ataatttcat tggcatagct ttgaaaaatt tgtcccgcat cagttagctc
     7861 aataccatgt gccgttcttt taaataattg cgcgcccaac tctttctcta attgttttaa
     7921 ttgatagctt aatggtggct gtgcaatata caagcgctta gcagctgctg taatctgctt
     7981 ttcttctgct acaactagaa aataacgtaa ctgttttaga ttcatattat ttatcctttt
     8041 tttatttcaa ttgatagtga tattaaaata tttaatatct tatattgtat tttagtattt
     8101 tattcatagc aatatctgtg ctaccttatt aaggtagatt tggagggaaa ataatgtctg
     8161 ataaatttca cggcttaact caagccgaag cagacaagcg cttaaaagaa gatggcttaa
     8221 atgaagtacc agagcctgaa tataatttct ttaaagagtt cttgtctaag ttatggaacc
     8281 tatccgcttg gattctagaa gctgctttaa ttctagaatg tatcttgggc aaatgggtcc
     8341 aatcattatt cgtgttgttg atgcttttat ttgctgcatt taacggtgca tctaagaaaa
     8401 agcaatcaag acgagtttta aataatattt cacacaagtt gactcctact gtatcagttg
     8461 aacgcgatgg caagtggatc aaacttgatt ctaaacaact agttaaaggc gatttaatct
     8521 cacttaaacg cggggacgta ctcgcagcag atgttaaaat tgttgacggt aacttagctt
     8581 gtgatgaaag ctcaattaca ggtgaatcta aaccagttaa gaaagcaatt gatgacaccg
     8641 cctttgccgg tactacagtt gttgaaggtg atggcctagc tgttgttact gctacaggta
     8701 aagattctag aagcggtaag acgattaatt tgatcaacaa ttccgctgct cctggtcact
     8761 tacaacaact tttgactaag attatctact acctttgctt actagatggt gttttaacct
     8821 tagttattat tatcgcctcc ttcttcaaag gcggtaattt caataccttt attaatatgt
     8881 tgccattcct ggcaatgatg tttattgctt caattcctgt agcaatgcca tcaacttttg
     8941 ctttatccaa ctcatttgaa gcaacccgct taagtaaaga aggagtcctg acttctgacc
     9001 taactggaat tcaggacgca gctaacttga acttgctttt acttgataag actggaacaa
     9061 ttacggaaaa caaaactgcc gtggccgctt ggactgatct aagtgacttg cctgataaag
     9121 acgtgcttgc cttagctgga gccgcaactg ataaacgtaa tgctggtatt atcgatacag
     9181 caatcgatga atacttagta gaaaataaca ttccagtcat gaatgctgaa aactttactc
     9241 catttacttc tgacactggt tattctatgg ctgatgttgc tggacataat gtaaagcttg
     9301 gttcatttaa gcaattatcc ttgatcgata aacatgccga tgaagaaatt tctggaatta
     9361 atttcaaggc aggacgctca gtggcagtct tgattgacga taagttagct ggtgtcttca
     9421 tcttacaaga taaagttaga acagactcta aagcagcttt ggctgaactc aagaaacgtg
     9481 gcgttcgccc aattatgtta actggtgaca atcaaaagac cgctgctgca gtggcagaac
     9541 aagttgattt aactggtgaa gtaatttcga ttcacgattt caatgaaaat actgatatta
     9601 atgatttggc cggtattgct gatgttttac cagaagataa actcaagatg gtaaagcttt
     9661 tccaagaaaa aggctatatc gtagggatga ctggtgacgg agttaacgac gcacctgcat
     9721 taaaacaagc tgaagtagga atcgcggttt caaatgctgc tgacgtagct aagcgttcgg
     9781 gtaaaatggt attactagac gatggtctag gctcaattgt taaaatttta gacgctggac
     9841 atcgcgtata ccaaagaatg actacttggt cactaaccaa gcttgctaga actgctgaat
     9901 taacgatgct gttaactttt ggctatcttt tctttgacta catcccaatg gccttgaatg
     9961 caatggttat ctataccatt atgaacaata tggttacgat gatgattggg acggaccgga
    10021 ctcacattac ttataagcca gaaaactgga atatggctaa gcttgctaag atcgcctttt
    10081 cactagctgc tggttggact ttaattggta ttgggtttgt ttggttctta aacacacacg
    10141 gttggagtca cggtgctgtt tctactatgg tttacgtata cctagttctt agcgcaatgt
    10201 tgattgtttt gattactaga actcgtaagt acttttggca agattaccca tccaagttgg
    10261 ttggtagtgt tcaaattgca gatgttctat tgacctttat cttagctctt tgtggttggg
    10321 caatggtcca aatttctatt caaaatctag caatcaccgt aattgtagcg attattgctg
    10381 ccataataat cgacttaatt taccaacctg tgatgaaaaa cagatagatt attaccataa
    10441 attttataaa ttaaaagact tctaggaact ttgaactctt agaagtcttt taatttatct
    10501 ttttgattca cgatatcctg ctgcacgtgc tgctgcttta ctcttgaaga aaaccgcatt
    10561 ttcacgattc attcgataat tatgaccgcg cattacgtga aagatttttg atcgtttatt
    10621 accaacaatt ctgtaattac cggtataaat cttagtttta tcacgatatt gatgctttct
    10681 ccttctgtga tgaatagctg cattaacaac tgatgtcgac ccctgcaaat ttgcaggcag
    10741 aacactgatt tctcccacta acatcagcaa tgcaacaata gtcacaaccc aattcttgca
    10801 tcttttcata aaaacactcc cttaatatgt cactatattt atatagtata cgcttatata
    10861 tgaagtgttc ctacgtttat tagaaactag tttcaattac ttatcttcat ttgcacctaa
    10921 aactgcaagc ccattagttg aaagatcatc accatattgt aaataaatat ctttcattct
    10981 ttgtgcatcc cacgcagtta aaatagtaaa tataatcaca gcaataatcg aaaaaacgta
    11041 gtcaatgatt ggattatgta aaaacaaatt aactaacatg gctacaatca acccaattaa
    11101 cgcagcagaa gcataggacc ctattcgact caaatctttt ttggtaattg ttcctaaaat
    11161 cgccattgtt acaaagacgg ttgccgaagc tacaaatgct gaagcaatat tttgtccact
    11221 ataggcacct gcaataaaag caaaggtaac gccgtaaaca attggtgttg tgcaataaag
    11281 gcagagatag gtcccgcaaa aaccgtcatt gtcaaatatg cactaattgc tgaaacgaaa
    11341 accgctaagg ccatataacc atatattttg ctaaaaaaac atttaatcct gaatcattag
    11401 catattgctg ttgaccagat tcttgatcaa aattatccat cttaatttct ccttcttaac
    11461 acataccctg tactttaaat ataacacctg tttaattaaa aacgtagcga gacaccctac
    11521 caaaatataa actatctcgg tccctttgaa ctagacctat aataaaaata tcatataatt
    11581 ggtatagaca attattaaaa atgaggtact attatgacaa tgagatcttt aggtctgtca
    11641 atttatccag gccacagcaa atttgaaggc aacgctcact atctggactt agctcacaaa
    11701 tatggctttt ctcgtatctt catgagtatg cttgaagtac aaggcagccc tgaaggaacc
    11761 aaagctaagt ataaaaaaat cattgaatat ggcaataaat tgggatttca aactttttta
    11821 gatgttaatc ctgccatctt caaacaacta ggtgtcagct atgatgacct gaaatttttg
    11881 ccgatattgg tgcagcaggc atccgtcttg acacaacatt tgatggtgca attgaagcaa
    11941 tgctttctta caacccatat ggtctaatca ttgaactcaa catgagtaat aatgttgact
    12001 atcttaacaa tattatttct taccaagcta atacaccgtt tatttatggc tgtcacaatt
    12061 tttatcctca acgcggtact ggcttacctt acgacttctt tatcgcttgt tctgaacgct
    12121 tcaaaaagtt tggctttcat tcagccgctt ttgtctcaag tcaagtaggt caaatgggac
    12181 cttggaacgt ggaagatggt ttaccaacgc ttgagcaaga ccggaattta ccaattgatg
    12241 tgcaagcaat gcatctctgg gcttctgggt tgattgatga tgtaatcatc ggtaatgctt
    12301 atgccagtga agccgagtta aaagccttat ctgaagttaa tcgctatcaa ttgatgttgc
    12361 acgtaaacta cgttaatgat gttaataaga ttgagaaaac tatcgtagaa gcgcctcaac
    12421 atttccgtcg tggtgatatc actaaggatg taattcgttc aaccatgccc cgtgtaactt
    12481 atgcagatat tcctaatcca gtacacgaca acaatgtaga attccaacgc ggagatatta
    12541 tcattggtaa cgacaacttt ggtcattaca aaaatgaact acaaattgtc cttgaacctc
    12601 ataaggagtc aaggatgaac aaagtcggtt ctattagatc agacgaatta ttcctgctcg
    12661 actttattaa accatggtca aaatttaaat taatcggtaa caaataataa aaacacctca
    12721 tgtcattatc tgtagacacg aggtgttttt ctacttgaat aaatcgttaa aactttcgct
    12781 cattgttggg tgagtataga tttgatcacg caaaatattt gctggaatct tcattttcat
    12841 tgccatacta atttgattaa ttagctcata agattcggca ccataaagag tgacgccaag
    12901 aatttggttg tttgcaggat taattaatgc tttaaataaa ccgcgtggat ccttcaatac
    12961 ttgagcctta ggaattgcag ttactggcag tttctttaat tcatatttga tattttggga
    13021 ttttgcttcc ttttcattca agccgacgcg agataatgtc ggcgtaatga atacactgta
    13081 tggtacattg attcgatcac tgactcttct ttgagcatcc ccatataatt gatccttgat
    13141 aatccgaaaa tcatcaagtg aaatataggt aaattgcgga ccgcctttga catcaccaat
    13201 tgcccaaaca ttttcgacgt tagttcttag ataatcatca accataattg tgccacgatc
    13261 attcaattca atatcagtat tttctattcc aagatcttca gtatttggtt ttcttcctgt
    13321 ggctactaaa attctatcag caactgttgt tgtagtcacg ccatcttttt catagtaaac
    13381 agtatggtca tctattctac tgatcttcac gcctaactca aatttcacgc cactattttc
    13441 aagatcatgc tttatctcga ccgcaatgtc atcgtcttca cgtggtaaaa agttatcatg
    13501 taaatcaagc acagttactt ctgagccata ttctgcaaac atcgatgcaa attctagacc
    13561 aatgtaacca gcaccaataa tcactagttt tttaggtaaa tttgtttgat ccattgcagc
    13621 agtcgaatca agaatagcat tactttccat taaaccagga attggcaaca taacaggcaa
    13681 agcaccagta ttgataaaaa ttctgtcacc atgaaattct tcgatttgat catttaccgt
    13741 ggttactgca atttcatgat tattcataaa cttagtggtg ccgtcaagta cggtaacatt
    13801 ctcttcatct gctaacatat gataattctt gttccgtagc attgaagtca tatcattttt
    13861 gccattgacc gcgtcaacaa aatcaacgcc attaccagct tcgataatta aacgcttaga
    13921 tggcaaacat gcaatattaa tacaagttcc accatacatc ttatctgact tctcaacaac
    13981 taaaacttct tcaccttttt gtgctaaaaa tttagctaga gtcttaccac ctttaccaaa
    14041 accaataata atgttcttta catttttcat aattacgcct ccctattctt aatatcctgt
    14101 tttccttatt gtggacgatc aagaataatt tatcatcttt tttgctttag aataaaaaac
    14161 aaatcctcct aaaagcgagt cgcctttaag aggattgtta tgaatttctg ttgatcgggc
    14221 atcgtgaaca aggattctcg atgcaacact ttctttagta taacgatgtt tgcaaattag
    14281 atcaagcgcg atttttatta gatatgtgct aaaagccaac tattcctgat caaatgtttt
    14341 ttctatgtga taccatggag atggattttc gaatatattc tagtccataa caccaatgac
    14401 tataatactt tttaggaaat agtttagtta gaaaaccagc cattaaggat tcaatcaata
    14461 ttttaattgt ctacttttta cgtctcagta caatttaatt ttctcttttt atttattcta
    14521 ttttaagcac catgatattg aacaagtgaa taaatatcaa catcaggtaa tttatctcta
    14581 ccgtgtaaat ctggcaattc gatgtagaat gcggcaccga ctaacttacc accaaggttt
    14641 tcaattagct ctttagaagc tcttaaagta cctgcggtag ccatcaagtc atcacagaca
    14701 accactcttt gtccaggttt aatcgcatcc ttgtgcattt ccaaactgtt tgaaccatat
    14761 tccaaatcat aggaagcacg ttcaacttct cttggtaact tatgtggctt tcttgcaggt
    14821 acaaaaccta aacctaactc agtagctact ggacaaccta caataaaacc acgtgcttca
    14881 ggcccaacaa ttacatctgc ttttttactc tttgcatatt ccgctaattc atgagtagcg
    14941 gcacgataca attcaccatc ttgcaaaatt ggtgtaatat cgcgaaaaac aatgcctttg
    15001 ttaggaaaat cctgaacact tgcaatatat ttactaaaat caactgccat aagaagcata
    15061 acctccaaaa ttctctgtgt ttgtgttcaa acgcttttga ccagtatatt ttaacaaatt
    15121 ttaacgataa aagcactgaa aacagaatag ttatctattt atttgtcaaa ttattaacat
    15181 atgtaatcaa acgttgacta ggcatagttc ttagttgatt aacaaattta atctgagaag
    15241 aagttcccat taaatattta gaagctgtca gcggctgttt tttaggagaa ggctctccta
    15301 ccaatttacc ttcatccaat tttacaaagc ctaattcaaa gaaaactcgt aaaatgaaaa
    15361 gcacactatc ataatctagt cccaaataag gtgcaactgt acggtaatct gctggcttta
    15421 acgtagggtg gctataaata tattttaaaa cagcaccaaa ataattttta gcgggaattt
    15481 gttcaacagg caattgatca agcaaaaagc gtaaatagat ttgttgataa tctttctcca
    15541 atgcagcatt taattcaatc tgattgcgtg gcacatctaa taatgcaact gtttcaccag
    15601 tttgatcata atctttaact aaagagatct tgtcttcatc gatctgtagt cggttgcgaa
    15661 caatcggaat atttttttga tcaaataaca ggtagcggtc cgcgaaaccc ataacatatt
    15721 tctcttggcg taagtcaaca actggcgttg gcactgccaa ttttggtgaa gcaaaagcta
    15781 gtccggtcat gattccttgt aaagaaactt gatttcgata agtatttaat gataattgaa
    15841 caaaaatttg agaaataaac ggcaaaagat tattattcaa aaagccttta ttaaatccaa
    15901 taactgataa gttaccgcct tttttagcaa ccgtaaattt gacatgattc ttatctttac
    15961 ccattttaaa gaaatgagtg attgttggat tagagatact aaagattggc tgcgtgtcac
    16021 ctgtcccaaa tggacctact tgattgattt gtgctagtgt ctgcggagtt aagccctgca
    16081 taggcaattc catgtcatat tttttagtct caagaccacc ttcaatatga aagtcatctt
    16141 caaatttttc ccgtaatggc gcaatctgat tttcttctaa tgataagcca caggcaaaat
    16201 catggccacc aaatttggtt aaatattgat ccttgatcgg atttaaagca tcaaacaagt
    16261 tgaaaccagc aaatgaccta cctgagcctt taacctcacc tgcatcattt ttagtcaaaa
    16321 caatcgtggg tttatgtgtc ttttcaacga tcttattagc tactaaacct aacacacctt
    16381 cgtgaaattc agggtcatat aaaaccaaag tattttgttt ttgccagcta tttttatgaa
    16441 ttaacgtcat acatttgtca taaacttcgg tggttaattc tttccgttta ttgtttaatt
    16501 cttcgatctt atctgcaatt ttttgggcct ccaggtcatc atcacttagc aaaagctcaa
    16561 ctgccaagtt ggcattatct aatcgaccta cagcatttaa tcgaggagca atattaaagc
    16621 cgacatcagt ttcattaata ctgcctaaag tcaaaccagc atttttgatt aaagcgcgca
    16681 agccaggacg atctgtctga ttaagcattt ctaaaccacg cttaacgata atatgcccct
    16741 ctccggtcac cttaaccata tcgccaatag ttccgatcat agccaaatct agcagctcag
    16801 gcatagtatc ctgcattaga ccacgacaaa tcgtgtaagc tactccggca ccacaataat
    16861 catcaaaagg atatttttgg ccaggataat tacaatgaac agtagcataa gctgccggtt
    16921 tcttttcttg aaaagtatga tgatctgtaa cgattacatc aacattatgt tcttgagcat
    16981 atttgacttc ctcgacccca gtaacaccat tatcaacagt gataatcaat ctggttccat
    17041 cagctacaat atcttgatag cggttcatat taggaccata cccatcattg aagcgattag
    17101 gaa
//
