LOCUS       c00084_gnlPro..        14037 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KEEDCBCM_84.
ACCESSION   c00084_gnlPro..
VERSION     c00084_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:42:28
            Original ID  :: gnl|Prokka|KEEDCBCM_84
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14037
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14037
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[591:12320]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      592..12320
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14037
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /kind="single"
                     /product="OD_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14037
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_AA_metabolism"
                     /region_number="1"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG,
                     Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /tool="gutsmash"
     CDS             592..4149
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EKR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_1"
                     /sec_met_domain="PFOR_II (E-value: 1.5e-17, bitscore: 52.6,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.4e-78, bitscore: 250.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.2e-36, bitscore: 112.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.3e-13, bitscore:
                     37.8, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_7 (E-value: 2.6e-11, bitscore: 32.8,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00012, bitscore: 11.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 9.5e-20, bitscore: 59.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRAKQSMDGNTAAAHVAYAYTDVAAIYPITPSSPMADSVDQWAA
                     AGQENIFGNQVVVSEMQSEAGAAGTVHGSLAAGAITTTFTASQGLLLMIPNMYKIAAEQ
                     LPCVFDVSARTVATQSLNIFGDHSDVYACRQTGFAMLAETNPQEVMDLSPVAHLAAIEG
                     KVPFINFFDGFRTSHEIQKIEKWDYADLKEMCNMDAVKAFREHALNPEHPAMRGSHENG
                     DVFFQHREACNSVYEALPAVVKKYMGKINEKLGTNYDLFNYYGAEDADRVIIAMGSICD
                     VAEEVIDYLTAKGEKVGLIKVRLYRPWVSSALLDVIPKTAKKIAVLDRTKEPGALGDPL
                     YLDVATTLREAGLNDIVLTAGRYGLGSKDTPPSSVFAIYKELEKDAPKSRFTIGIVDDV
                     TNLSLPEVKPAPITSAPGTVECKFWGLGGDGTVGANKNSTKIIGDHTDKYIQAYFQYDS
                     KKTGGITISHLRFGDNPIRSPYYINQADFVACHNPSYVVKGYKMVQDVKPGGIFMINCQ
                     WSDEELDHHMPAAAKKYIADNNIQLYTINAIDKAIEIGMGKRTNTILQSAFFKLANIMP
                     IDEAVEFMKAAAKKSYSKKGDAVVEMNYKAIDAGVDAVHKVEIPASWFNPAADAPAKEL
                     TGRPETVKMVKEMMEPIGIMDGDSLPVSTFVDNADGQFELGASAYEKRGTAVSVPEWNP
                     EACIQCNQCAFVCSHATIRPFLVSEDEIKAAPDNMKVADTKPKASEYKFTMSVSPLDCM
                     GCGECITVCPAAAKGALKMVPQESQAAEQPVFDYLVATVGRKPGAPADTTVKGSQFNQP
                     LLEFSGSCAGCAETSYARLITQLFGEHMYISNATGCSSIWGGPAATAPYTVNKDSKQGP
                     AWANSLFEDNAEHGFGMYLGQKTLRDQAIAKLEKMAASDKASDEFKAAFAKFMETKDNT
                     KENTPDAQALIAEVEKAAAAGCPDAAEVLEKKQYLAKKSVWIFGGDGWAYDIGFGGLDH
                     VLASGENVNVMVFDTEMYSNTGGQASKASNIGEVCQFAAAGKEISKKSLAEIAMSYGYV
                     YVAQIALGANPNQAVKCLAEAEAYNGPSLIIGYAPCELHGIAKGGMNHCQDEMKKAVKA
                     GYWNLFSFDPAKKAEGKNPFTLTSKEGDGSYQEFLNNESRYTRLIKPFPERAERLFNES
                     EKVAKARYEHLQRLVELYK"
     CDS             4352..6106
                     /locus_tag="ctg84_2"
                     /transl_table=11
                     /translation="MLYKEDFGEGKNIEFKREIPKRHEKLLKDVIAFSNFTGGKIFIGI
                     EDKTNEVIGIGEKNPFRLADDISNMIFDSCTPIIDPEITIQTLEGRTVVVVEVFPGRMR
                     PYYLKSFGKEQGSYIRINDTSRPADDRKLKELELEGQKISYDTLPEIDMEYSEREAKIL
                     CNAMEKVAYDVQTTCVTRAIQETSLDPKQNTEKTEIINKMTIEKLEDLGLLCRIGKDLQ
                     PTHAFRLMTKNKIRYAKIQCALFKGTERDIFIDKREFDGPLYVQLENAYQFVLKHINLG
                     AKIEGLHRKEAYELPVRTIRELITNAVVHRSYLDESCIQVCVYDDRIEVTSPGMLYGGL
                     DIQSAKSGKSKCRNTAIAEAFRYMGLIEAWGTGIPRMIKECREYGLREPVFEELGDGIR
                     VTIFRENEELEMRKRAENIQNAENKYQYMNNINSENLASVVKEQTVEYREQNHCFNTEK
                     SLFNALDSQGNEKKYCLNDEKTLFETTSQDKTHCFETSVLTAENKYMLYKKLKELQVNK
                     SIGSVTALNIKEIIESFSGEEVFGRKEIKQKLGYKDSKAGFLIQTMREFELIKDVKGRG
                     KGKYCFDI"
     CDS             complement(6210..6878)
                     /locus_tag="ctg84_3"
                     /transl_table=11
                     /translation="MIINKFYEKLYKELINKLESDYILIPNTPENRKAINNTLTTVPCT
                     VKSLEKDSKIFKALSNKKAKAKQLSIVPKISKTLSLIIIATLICMPFNTINTLPTPTYH
                     PTVQVSILDISDGSSHQKGKNKLSEIQEQYTNKNQEQRNPKNYKKKVATNTYNTYKKQN
                     KFHLTLSTKKATQLLSTFKKFFLKTKNTYDNLSDAYDVISTLFVLISTVKESIRSKKLK
                     "
     CDS             complement(6875..6964)
                     /locus_tag="ctg84_4"
                     /transl_table=11
                     /translation="MLKFDTERRGHFAKKYAFIIIEKRKEKSQ"
     CDS             7785..12320
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: Glu_syn_central"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: Glu_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_5"
                     /sec_met_domain="GATase_2 (E-value: 5.1e-173, bitscore:
                     564.2, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Glu_syn_central (E-value: 1.2e-112,
                     bitscore: 364.6, seeds: 570, tool: rule-based-clusters)"
                     /sec_met_domain="Glu_synthase (E-value: 7.8e-154, bitscore:
                     500.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYQDNMRQGLYDPSLEHDNCGIGAVVNIKGLKSHETVSNALKIVE
                     NLEHRAGKDAEGKTGDGVGILVQISHKFFEKTCSTLGFSIGKERDYGIGMFFMPQDELQ
                     RNRAKKMFEIIVEKEGLNFLGWREVPVQPGILGKKAADCMPCIMQGFVKRPFDVPRGLD
                     FDRRLYIVRRVFEQSNDSAYVVSLSSRTIVYKGMFLVGQLRLFYNDLQDKDYESAIALV
                     HSRFSTNTVPSWEKAHPYRYIVHNGEINTIRGNADKMLAREENMESDYLKDEMIKLTPV
                     VDPNGSDSARLDNTLEFLLMSGMPLPLAMMITIPEPWENNEGMSREKRDFYQYYATMME
                     PWDGPASILFTDGDIMGAVLDRNGLRPSRYYITDDDQLILSSEVGVLDFDTTHIVKKER
                     LHPGKMLLVDTVKGELIDDEILKDSYVKNQPYGEWLSDNLVFLKDLKIPNVAVEEYSYE
                     ESNRLMKAFGYSYEEVKDSVLPMALNGSEAIGAMGVDTPLAVLSKRHHPLFDYFKQLFA
                     QVTNPPIDAIREEIVTSTSIYVGGEGNVLEEKAENCHVLKIHNPILTNTDLLKIRYAKV
                     KNINVKDVPITYYKGTPLDKAINHLYVAVDQAHKNGANVVILTDRGVDENHVAIPSLLA
                     VSAVHHHLIETKKSTSVSIILESGEPREVHHFATLLGYGACAINPYLAQFSIKKLIQDG
                     LLKKDYYAAVNDYNNAVLHGIVKIASKMGISTLQSYQGSQIFEAVGISKKVIDEYFTNT
                     VSRVEGITIEDIAEDVDYHHSKAFDMLGLKNDLSLDSEGDHKYRSGKEEHLYNPLTIHT
                     LQTAAWTNNYELFKQYTSMINKETSPVSLRGLMDFNYPSKGVPIEEVESVDSIVKRFKT
                     GAMSYGSISKEAHETLAIAMNMIHGKSNTGEGGEDLERLTVGPDGLNKCSAIKQVASGR
                     FGVTSRYLVSAQEIQIKMAQGAKPGEGGHLPAGKVYPWIAKTRHSTPGVGLISPPPHHD
                     IYSIEDLAQLIYDLKNANRNARISVKLVSEAGVGTVAAGVAKAGAQVILISGHDGGTGA
                     APRNSSIHNAGLPWELGLAETHQTLIKNDLRNKVIIETDGKLMSGRDVAMAAALGAEEF
                     GFATGPLITMGCVMMRVCNLDTCPVGIATQNPELRKRFKGKPEYVVNYMKFVAQEMREY
                     MAKLGVRTVDELVGRTDLLKELPEAKEYHLDLSAILNNPYVDKKHPICYNKKNEYNFEL
                     EKTLDEKVLLTKLKTALDKKQKRSISIDVGNTDRSFGTIFGSEITKKYYNTLEDDTFTV
                     QCTGAGGQSFGAFIPNGLTLELVGDSNDYFGKGLSGGKLIVYPPKGIRFKAEENIIVGN
                     VALYGATSGQAYINGVAGERFCVRNSGATAVVEGVGDHGCEYMTGGKVLIIGKTGKNFA
                     AGMSGGVAYVLDEDNDLYLSLNKEMVSSEPVVSKYDVMEIKDMITAHVAYTNSEKGKEI
                     LNDFSKYLPKFKKIIPHDYKKMLKKISEMEGKGLSAEQAQIEAFYEIKRG"
     CDS             12333..13817
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_20"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:Dihydroprymidine dehydrogenase domain II, 4Fe-4S
                     cluster (Score: 69.9; E-value: 4.8e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg84_6"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.4e-27, bitscore:
                     82.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_20 (E-value: 4.6e-23, bitscore: 69.9,
                     seeds: 204, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKPTGFLEYERKESVGEAPLKRIKHFNEFHTPLSKKEQERQGAR
                     CMNCGVPFCQSGILIKGMVTGCPLNNLIPEWNDATYTGNWDEAYNRLRKTNPFPEFTGR
                     VCPHPCEVGCTCNLGGDPVNIKEKELSIIERAYESGLIKPEPPEVRTGKTVAIVGSGPS
                     GLCVAEYLNRRGHSVTVYERSDRVGGLLMYGIPNMKLEKTYIERKVKLMEKEGVVFKTG
                     VNVGVDVKAQDLKKQYDAVVLCCGASNPRDIKAPGRKSKGIYFAVDYLKAATKSLLDSN
                     FADKKYIDAKDKNVMVIGGGDTGNDCVGTSIRLGCKSLIQLEMMPKLPDERQPNNPWPE
                     WPRVCKTDYGQEEAIAVFGKDPRVYQTTVKEFIANEKGEVCKAKLVKLESKFDKKAGRN
                     IMAEVAGSEYEVPVDLVLIAAGFLGSQPYVTKAFGLDLTERTNVKTVEGHFKTNVDKVF
                     TAGDMHRGQSLVVWAIREGRDCAREVDKALMGYSNL"
ORIGIN
        1 tagagcgtgt ttgaaaaata aaagttatac aaaacacaag agttattact gcttgttgat
       61 actgaaaata tcaaaaataa atattattta tatcataatt gacatatttt aaagacatat
      121 atgcagtata taataattga ttttggcaat ataaataact ttaaatattt ttcaaacacg
      181 ctctagtcga ttaaattatg taaaattacg aaattgttat ttttaaaaga tggagataaa
      241 tggtgaaaac aaagagaaat ctcataaaat aattaaaaaa tgaagaaaaa atattagaat
      301 tttaatcctg aataatccta aaattacaac aaaaaattat tgagaaaaaa tctaaaataa
      361 gccatatgta tattgtatac aaaactgttg gctttatagc aattttaacc taaaattgtt
      421 ctcggaaaaa tacgttgtca aggggaaaaa ttggcataaa aaggctgttt cgggcaagat
      481 tttgtatttt agaaggaaca gttccgaata agctttacat tacctcaaaa aaatgataat
      541 attatgtcga atttaaaata aaccacaact tttgacaagg aggaataatc aatgcctaga
      601 gcaaaacagt ctatggatgg aaataccgca gcagctcacg tagcatatgc gtatacagat
      661 gttgcagcta tctatcctat tacaccatct agtccaatgg ctgattccgt tgaccagtgg
      721 gcagcagcag gacaggaaaa tatttttggt aaccaggtag ttgttagtga gatgcagtct
      781 gaggcaggtg cagcaggtac tgttcacggt tctcttgcag ctggtgctat cacaacaaca
      841 tttacagcat cccagggtct tcttcttatg atccctaaca tgtataagat cgcagctgag
      901 cagcttccat gtgtatttga tgtatctgca cgtacagttg ctacacagtc tctgaacatt
      961 ttcggtgacc acagtgacgt atatgcatgt cgtcagacag gatttgctat gctggcagaa
     1021 actaacccac aggaagttat ggacttaagc cctgtagcac atcttgctgc aatcgaaggt
     1081 aaagttccat tcatcaactt cttcgatggt ttccgtacat ctcatgagat tcagaagatc
     1141 gaaaaatggg attatgcaga cttaaaagaa atgtgcaaca tggatgcagt taaagctttc
     1201 cgtgagcatg ctcttaaccc agaacaccca gctatgcgtg gttctcacga aaacggtgat
     1261 gttttcttcc agcacagaga agcttgtaac tctgtttacg aagctttacc agctgttgtt
     1321 aagaaataca tgggcaaaat caacgaaaaa ctgggaacta actacgattt attcaactac
     1381 tatggtgcag aagatgcaga ccgcgtaatc atcgctatgg gatctatctg tgacgtagca
     1441 gaagaagtaa ttgattactt aacagcaaaa ggtgaaaagg ttggtttaat caaagttcgt
     1501 ttatatcgtc cttgggtatc ttctgcatta ttagatgtta ttcctaagac agctaagaag
     1561 atcgctgttc ttgaccgtac aaaagagcct ggagcattag gagatccttt atatcttgat
     1621 gttgctacaa ctcttagaga agcaggtctt aacgatatcg ttcttacagc tggacgttac
     1681 ggattaggtt ctaaagatac tcctccttca tctgtatttg ctatttataa agaacttgaa
     1741 aaagatgctc caaagagccg tttcacaatt ggtatcgtgg atgatgttac aaacttatct
     1801 ttaccagaag ttaaaccagc tcctatcaca tctgctcctg gtacagtaga gtgtaagttc
     1861 tggggtcttg gtggagacgg tactgtaggt gctaacaaga actctacaaa gattatcggt
     1921 gaccacacag ataaatacat tcaggcatac ttccagtatg actccaagaa gacaggtggt
     1981 attacaattt ctcaccttcg ttttggtgac aatccaatca gaagcccata ctacattaat
     2041 caggctgact tcgtagcatg tcacaaccca tcttatgtag ttaaaggtta caagatggtt
     2101 caggatgtta aaccaggcgg aatcttcatg atcaactgcc agtggtctga tgaagaatta
     2161 gatcatcata tgcctgcagc agctaagaag tatattgctg acaacaacat tcagttatac
     2221 acaatcaacg cgattgataa ggctatcgag attggtatgg gtaaacgtac taacacaatc
     2281 ttacagtccg cattcttcaa attagcgaac atcatgccta tcgacgaagc agtagaattc
     2341 atgaaagcag cagctaagaa gtcctacagc aagaagggtg acgctgttgt agagatgaac
     2401 tacaaagcta tcgacgctgg tgtagatgct gttcataaag tagagattcc agcttcctgg
     2461 tttaacccag ctgctgatgc tcctgctaaa gaacttacag gacgtccaga gacagttaag
     2521 atggttaagg aaatgatgga acctatcgga atcatggatg gtgacagcct gccagtatct
     2581 acattcgtag acaacgctga cggacagttc gaacttggtg cttccgcata cgaaaaacgt
     2641 ggtactgctg tatctgttcc agaatggaat ccagaagctt gtatccagtg taaccagtgt
     2701 gcgtttgtat gttcccatgc tacaattcgt cctttcttag taagcgaaga cgaaattaag
     2761 gcagctcctg acaacatgaa agttgcagat acaaagccaa aggcaagcga atacaaattt
     2821 acaatgagcg tatctccatt agactgtatg ggatgtggtg agtgtatcac agtttgtcct
     2881 gctgcagcta agggcgcatt aaagatggtt ccacaggaaa gccaggcagc agaacagcca
     2941 gtattcgatt acttagttgc aactgttgga agaaaaccag gtgctcctgc agatactaca
     3001 gttaagggat ctcagttcaa ccagccatta cttgagttct ccggatcttg tgcaggatgt
     3061 gcagagacat cttacgctcg tctgattact cagttattcg gagagcatat gtacatctcc
     3121 aacgcaacag gatgttcatc catctggggt ggtcctgcag caacagctcc atatacagta
     3181 aacaaagatt ccaaacaggg accagcttgg gcaaactcct tattcgagga taacgcagag
     3241 cacggctttg gtatgtatct tggacagaag actttacgtg accaggctat cgctaaatta
     3301 gagaagatgg cagcatccga taaagcatcc gatgaattta aagcagcatt tgctaagttc
     3361 atggaaacaa aagacaatac aaaagaaaat acacctgatg ctcaggcatt aatcgctgag
     3421 gtagaaaaag cagcagcggc tggatgccca gatgcagcag aagtattaga gaagaaacag
     3481 tatctcgcta agaagtccgt atggatcttc ggtggtgacg gatgggcata tgatatcggt
     3541 ttcggtggat tagaccatgt attagcttcc ggtgagaacg taaacgttat ggtattcgat
     3601 actgagatgt actctaacac aggtggacag gcttctaaag cttctaacat cggtgaggta
     3661 tgtcagttcg cagcagctgg taaagaaatc agcaagaaga gccttgcaga gatcgctatg
     3721 agctacggat acgtatacgt tgcacagatt gctcttggtg ctaaccctaa ccaggcagtt
     3781 aaatgtcttg cagaagcaga agcttacaac ggaccatccc tgatcatcgg atacgctcca
     3841 tgtgaacttc acggtattgc taagggtggt atgaaccact gtcaggatga gatgaagaaa
     3901 gccgttaagg ctggttactg gaacctcttc tccttcgacc cagctaagaa agctgaagga
     3961 aagaatccat tcacattaac atctaaagaa ggcgacggat catatcagga attcttaaat
     4021 aacgaatccc gttacactcg tctgattaag ccattcccag aaagagctga aagactcttc
     4081 aacgaatctg agaaggttgc taaggctcgt tacgagcacc tgcagagact cgttgagctt
     4141 tataaataat aaagcctgaa ctggtcagtc agattagtta tacaaaagat aaaactactt
     4201 tatgaaatac aaaagagaag ctatgtgtca gctatgctga tgcatggctt cttcttgtat
     4261 gttgaaaaaa agaagggaat tgtattataa taaatcataa caaattaatg actgatagat
     4321 gtactgacaa tggttttgaa gagggacagg aatgctatat aaagaagatt ttggagaagg
     4381 aaaaaatata gaatttaaaa gagagatacc gaaaagacat gagaagttat taaaagatgt
     4441 tattgctttt tccaatttta cggggggtaa aatttttatt ggaattgagg ataagacgaa
     4501 tgaagttatt gggattggag agaagaatcc atttagatta gcagatgata tttcaaatat
     4561 gatatttgac agctgcactc caataattga tccggaaatt acaatacaga cattagaagg
     4621 aagaacagtt gttgttgtag aagtttttcc aggacgtatg cgtccttatt atctcaagtc
     4681 atttgggaag gaacaaggtt cttatataag aataaatgat acaagtcgtc ctgctgatga
     4741 tagaaagtta aaggaactag aattagaagg tcaaaagatt tcttatgata ctttaccgga
     4801 aatagacatg gagtactcgg aacgagaggc gaagatatta tgtaatgcaa tggaaaaagt
     4861 ggcatatgat gtgcagacaa catgtgtaac aagagcaata caggaaacgt cattagatcc
     4921 caagcaaaat acagaaaaaa ctgaaattat aaataaaatg acaatcgaga aactagaaga
     4981 cttagggtta ttgtgccgaa taggaaaaga ccttcaaccc acccatgcgt ttagactaat
     5041 gacgaagaat aaaatacggt atgccaaaat tcaatgtgcg ttatttaaag gaacagaaag
     5101 agatattttt atagataaaa gagaatttga tggaccatta tatgtacagc tggaaaatgc
     5161 ttatcaattt gtattaaagc atatcaatct tggtgcaaag atagaagggt tacatagaaa
     5221 agaagcgtat gaactcccgg ttcgaacaat aagagaattg attactaatg cagttgttca
     5281 tagaagttat ttggatgagt cttgtataca ggtttgtgtc tatgatgaca ggatagaagt
     5341 aacatctccc ggaatgcttt atgggggact ggatatacag tcagctaaat caggtaaatc
     5401 aaagtgcaga aatacagcga ttgctgaagc atttcgttat atgggactta tagaagcgtg
     5461 gggaacagga atcccaagaa tgataaaaga atgcagagaa tatgggttga gagagccagt
     5521 gtttgaggaa ctgggagatg gtatacgagt aactatattc cgggaaaatg aagaattgga
     5581 gatgcgaaaa cgggcggaga atatacagaa cgctgaaaat aaataccagt atatgaataa
     5641 tataaatagt gagaacttag catctgtagt aaaagaacaa acagtggaat atagagagca
     5701 aaatcactgt ttcaatacag aaaaatcact gtttaatgcg ctggattcac aaggaaatga
     5761 aaaaaaatac tgtttgaatg atgaaaaaac actgtttgaa acaacaagtc aggataaaac
     5821 ccactgtttt gaaacgtctg tattgactgc agagaataaa tatatgttat ataaaaagct
     5881 gaaagaacta caagttaata aaagcatagg tagcgtcact gcattaaata taaaggagat
     5941 tatcgaaagc ttttcaggag aagaagtctt tgggcgaaaa gaaataaaac aaaaactggg
     6001 atataaagac agtaaggcgg gatttctgat tcaaacaatg cgggaatttg agttgattaa
     6061 agatgtgaaa ggaaggggca agggaaagta ttgttttgat atttaaaact ctatcttggc
     6121 tttcataaga aaatttaaag ccgtacttct gtgaagaacg gctttaatgt ataattgaaa
     6181 atagtattga ataaaattat atagaaggac tattttaatt tttttgagcg tatagattct
     6241 tttactgtgg aaatcaatac aaataaagta ctaattacat cataagcatc agataaatta
     6301 tcgtatgtat tttttgtttt aagaaaaaac tttttaaaag ttgataaaag ttgagttgct
     6361 ttttttgtgg ataatgttaa atggaattta ttttgtttct tatatgtatt atatgtattt
     6421 gtagcaactt tctttttgta gtttttagga ttacgttgct cttggttttt gtttgtgtat
     6481 tgttcttgta tttcggataa tttatttttc cctttttggt gagaagatcc atcagaaata
     6541 tctaaaatac taacttgtac agtagggtgg taggtaggcg ttgggagagt gttaatggta
     6601 ttaaatggca tacaaattaa agtggctatt ataataagag ataaagtttt agaaattttg
     6661 ggtacaattg aaagctgctt agctttagct tttttgttag ataaagcttt aaaaatcttt
     6721 gaatcttttt ctaaagattt tacagtgcaa gggactgtcg ttagagtatt attaattgct
     6781 tttctatttt ctggcgtgtt agggattaaa atataatcag attctagttt gttgataagt
     6841 tccttgtaga gtttttcata aaatttgtta ataatcattg tgatttctcc tttctttttt
     6901 ctataataat aaatgcgtat ttttttgcga aatggcctct cctttctgta tcgaatttca
     6961 acattttttg ttgattatta ttaatatgta taattttttc tttttgtatt gctctgattt
     7021 gccatgtgtg taattaaaat ctcctttctt acattagtat gagagattag ggaaattttc
     7081 tttttgaaaa gacagtttac gaaaaaagaa tccgattctt tttttgcttt ttcactacaa
     7141 atagtatgct agtttagaca atggcataaa attgtagaat tcaaccaatt acttacttaa
     7201 ttttcttaag ttattttgta tacaatgtta ataaaatgca ggatttgtat ttgaaaatta
     7261 catttataat tgtatgaatt gtctttaaat ctgaaaataa cgatgaataa agaggtgaaa
     7321 tcacaaacaa aattgtactt ttataagaac aatataatct aaaaagaaat aaaaaccaaa
     7381 taaactaact acaatatccc ctaaaacaag agtaataatc agaaaataat atattaaaaa
     7441 ataaataatc aaattattag acaactcacc ttaatgttta tatttacaac ctatttaaaa
     7501 tgttgtaata tgataacaac aaaaagaaat gcaggaagtc attacaacta cttctgaaaa
     7561 tgaatttgtt actttttaaa tatgtaatta ttcagagatt tatagatttt tattcagact
     7621 atagatactc attcaggatt atgaaatcat aagattacaa gagcatgaga acatgagaat
     7681 cataaggttt gattaagagt tcctgataat tactaattac aaaaatataa tttacaactg
     7741 atgaatattt actatttcat agtgatgcaa gaaagggtga gaccatgtat caggacaata
     7801 tgcgacaggg tctatatgat ccaagtctgg agcatgataa ctgtggtatt ggtgctgtag
     7861 taaacatcaa gggtcttaag agccatgaga cagtatcgaa tgccttgaaa attgttgaaa
     7921 atcttgaaca tagagccggc aaggacgccg agggtaaaac gggtgacgga gtaggtatct
     7981 tagtgcagat atcccataag ttcttcgaaa aaacctgtag tactctcggc ttttctattg
     8041 gcaaggaacg tgactacggt attggtatgt tctttatgcc acaggatgag ttacagagaa
     8101 accgtgctaa gaagatgttt gagattatcg ttgaaaaaga aggcttaaat ttcttaggct
     8161 ggagagaggt tccggttcag ccgggcatcc tcggaaagaa agcagcggac tgtatgccat
     8221 gcattatgca gggatttgta aagagaccgt ttgatgttcc acgaggactt gacttcgata
     8281 gaagacttta tattgtaaga cgagtatttg agcagtctaa cgattctgct tatgttgttt
     8341 ctttaagcag cagaacaatc gtatataaag gtatgttctt agttggacag ttaagattat
     8401 tctataatga ccttcaggat aaggattatg aatctgcaat cgcattagtt cattcccgtt
     8461 tctccacaaa cacagttcca agctgggaga aagcacatcc ttatcgttac atcgttcata
     8521 atggtgagat taatactatt cgtggtaatg ccgataagat gttagcccgt gaggaaaaca
     8581 tggaatctga ttatctgaag gatgagatga ttaagctgac accagttgta gatccaaacg
     8641 gttctgactc tgcaagatta gataatacat tagaattcct cttaatgagt ggaatgccac
     8701 ttcctctggc aatgatgatc acgattccag aaccttggga aaataacgag ggcatgagca
     8761 gagagaagag agacttctat cagtactacg caacaatgat ggagccttgg gatggtcctg
     8821 catctatcct ctttacagat ggagatatca tgggagccgt acttgaccgt aatggtctta
     8881 gaccttcccg ttactatatt acagatgatg accagttaat tctttcttct gaggttggtg
     8941 tgttagactt tgacacaaca catatcgtaa agaaagagag acttcaccca ggtaaaatgc
     9001 ttctcgtaga tactgtaaaa ggtgagctga ttgacgatga aatcttaaaa gattcttatg
     9061 taaagaatca gccttacggt gaatggttat ccgataacct tgtattctta aaagacttaa
     9121 agattccgaa tgttgcagta gaagaataca gctatgaaga gagcaaccgc ctgatgaaag
     9181 catttggtta ctcttatgaa gaagtgaaag attctgtatt accgatggca ttaaacggaa
     9241 gtgaagcaat cggagcgatg ggggttgata ctccattagc agtactttct aagagacatc
     9301 atccattatt tgattacttt aaacagcttt ttgcacaggt aacaaaccct cctattgatg
     9361 cgattcgtga ggaaatcgtt acatctactt ccatctatgt tggcggagag gggaatgtgt
     9421 tggaagaaaa ggcagaaaac tgccatgtat taaagattca caaccctatt ttaacaaata
     9481 cagacttatt aaagattcgt tatgcaaaag taaagaatat caatgtaaaa gatgtgccga
     9541 ttacttatta caaaggaaca ccgcttgata aggctatcaa tcatttatat gttgctgttg
     9601 accaggcgca taaaaatggt gcaaatgttg ttattttgac agatagaggt gttgatgaga
     9661 accatgtggc aattccatct ctgttagcag tatctgctgt acatcatcat ctcattgaga
     9721 caaagaagag tacttctgta agtattatct tagagagtgg tgagccaaga gaagtacatc
     9781 attttgcaac actgttaggt tacggcgcat gtgctatcaa cccatatctg gcacagttca
     9841 gtattaagaa gctgattcag gatggtttat taaagaaaga ttactatgca gcagtaaatg
     9901 attacaataa cgcagtactt cacggtatcg taaagatcgc atctaagatg ggtatttcca
     9961 cactgcagtc ctatcagggt tctcagattt ttgaggcagt tggtatcagc aagaaagtca
    10021 ttgatgagta ctttacaaac acagtaagcc gtgtagaagg tatcacaatt gaagatatcg
    10081 cagaagatgt agattaccat cactccaaag catttgatat gttaggactg aaaaatgatc
    10141 ttagtcttga cagtgaaggt gatcacaaat atagaagtgg taaagaagaa catctttaca
    10201 atccactgac catccataca ttacagacag cagcatggac aaataattat gaactgttta
    10261 aacagtatac ttccatgatt aataaagaaa cttctccagt aagtcttcgt ggattaatgg
    10321 atttcaatta tccgtccaaa ggagttccta tcgaagaagt tgaatctgta gattctatcg
    10381 tgaaacgatt taagacaggt gctatgagtt atggttctat ttccaaggaa gcacatgaga
    10441 ctctggcaat cgcgatgaac atgattcacg gtaaatcaaa cactggtgaa ggtggagaag
    10501 atttagagcg tctgacagtt ggtccagatg gactgaataa atgctctgca atcaagcagg
    10561 tagcttccgg tcgtttcggt gtaacaagcc gttaccttgt aagtgcacag gaaattcaga
    10621 ttaagatggc acagggagca aaacctggtg aaggtggaca tttaccagca ggaaaagtat
    10681 atccttggat tgcaaagaca agacattcaa cacctggtgt aggactaatc tcaccaccac
    10741 ctcatcacga tatttacagt attgaagatt tggcacagtt aatttatgat ttgaaaaatg
    10801 caaacagaaa tgcccgcatt tctgtaaaac tggtatctga agcaggtgtc ggaacggtcg
    10861 cagccggtgt agcaaaagct ggcgcacaag taatccttat ttccggacat gacggtggta
    10921 caggtgcagc acctcgtaat tcttctatcc ataatgccgg acttccgtgg gagcttggac
    10981 ttgctgagac acaccagaca ttaattaaaa atgaccttcg taataaagtt atcatcgaga
    11041 cggacggtaa gcttatgagc ggccgcgacg tagcaatggc agcagcactt ggagcagaag
    11101 aatttggatt tgctactggt ccgctgatca caatgggctg cgttatgatg agagtttgta
    11161 acttagatac ttgtccagta ggtatcgcaa cacagaatcc ggaacttaga aaacgtttca
    11221 aaggtaaacc ggaatacgtt gtaaactaca tgaagttcgt tgcacaggaa atgcgtgaat
    11281 acatggcaaa acttggtgtc cgcactgtag atgaactagt aggacgtaca gaccttctga
    11341 aagaacttcc agaagcaaaa gagtaccact tagatttatc tgctatttta aataatccat
    11401 atgtagataa gaagcatcca atctgctaca acaagaagaa tgaatacaac tttgaattag
    11461 aaaagacatt agatgaaaaa gttcttctta ctaagttgaa gacagcgctt gataaaaagc
    11521 agaagagaag catttctatc gatgttggaa atacagaccg ttcctttggt acaatctttg
    11581 gttctgaaat tacaaagaaa tattacaaca cactggaaga tgatacattt actgtacagt
    11641 gtacaggagc cggcggacag agctttggag catttattcc aaatggtctt acattagagc
    11701 ttgtcggtga cagtaatgac tacttcggaa aaggattatc cggtggtaaa ttaatcgttt
    11761 accctccaaa aggaatccgc ttcaaagccg aggaaaatat tatcgttggt aacgtagcac
    11821 tttatggtgc aacaagcggt caggcttata ttaatggtgt ggctggtgaa cgtttctgtg
    11881 ttcgtaactc cggtgcaaca gccgttgtag aaggtgtcgg cgatcacgga tgcgagtaca
    11941 tgactggtgg taaagtctta attatcggta agactggaaa gaactttgca gccggaatga
    12001 gcggcggtgt tgcctacgtt cttgatgagg ataacgactt atacttaagc ctcaacaagg
    12061 aaatggtttc ttccgaacca gttgtttcta aatatgatgt tatggaaatt aaggatatga
    12121 ttaccgccca tgtggcatat acaaactctg aaaaaggtaa agaaatttta aatgatttta
    12181 gcaaatattt accgaagttt aagaaaatca ttccacacga ttacaagaaa atgctcaaga
    12241 agatttccga aatggaagga aaaggtctta gcgcagagca ggcacagatt gaagcatttt
    12301 acgaaattaa aagaggatag gaggagagcg ctatgggaaa accaactgga tttttagaat
    12361 atgaacgaaa agaaagcgtg ggagaagcgc cgttaaagag aatcaaacat tttaacgaat
    12421 ttcacactcc cctgtccaaa aaagaacagg agagacaggg agcaagatgt atgaactgtg
    12481 gagttccatt ttgccagtcc ggtattttga ttaaaggaat ggttaccgga tgcccgctta
    12541 ataatctgat tcctgaatgg aatgatgcaa cttacacagg taactgggat gaagcttata
    12601 accgtcttag aaagacaaat ccatttccag aatttacagg tcgtgtatgt ccacatcctt
    12661 gtgaagtcgg atgtacctgt aacttaggcg gggatccggt taacatcaaa gaaaaagagt
    12721 taagtattat agagcgagct tatgaaagtg gcctgatcaa accggaacca ccagaagtcc
    12781 gcacaggaaa gacagttgct atcgtaggtt ccggtccatc cggactctgc gtggcagaat
    12841 acttaaaccg ccgtggccat tctgtaactg tttacgagcg ttccgaccgt gttggtggac
    12901 tgctcatgta cggaattcct aacatgaagc ttgaaaaaac atatattgag agaaaagtaa
    12961 agctcatgga aaaagaaggc gttgtattca agacaggcgt aaacgttggt gtagacgtaa
    13021 aagcacagga cttaaagaaa cagtatgatg ctgttgtact ttgctgtgga gcctctaatc
    13081 caagagacat caaagcacca ggcagaaaga gcaaaggaat ttattttgca gtagattact
    13141 taaaggcagc aacaaagagc cttttagatt ctaacttcgc agataaaaaa tacattgatg
    13201 ccaaagataa aaatgtaatg gttatcggtg gcggtgacac aggaaatgac tgtgttggaa
    13261 catccatccg tttaggatgt aagagcctca ttcagttaga aatgatgcca aaacttccag
    13321 atgaacgtca gccaaataac ccatggccag aatggcctag agtctgcaag acagactacg
    13381 gtcaggaaga agctatcgct gtatttggca aagacccacg agtatatcag acaaccgtaa
    13441 aagaattcat tgccaatgaa aaaggcgaag tctgcaaggc aaaactcgta aaacttgaaa
    13501 gtaaattcga caaaaaagcc ggaagaaata tcatggcaga agtcgctggt agcgagtatg
    13561 aagtacctgt tgatttggta ttaatcgcag caggattctt aggaagccag ccatatgtta
    13621 caaaagcttt tggcttagat cttacagaac gcacgaatgt aaagacagta gaaggacatt
    13681 tcaagacaaa tgtagataaa gtctttactg ccggtgatat gcatcgagga cagtcacttg
    13741 ttgtatgggc aattcgcgaa ggtcgggact gtgcaagaga agttgataaa gccctgatgg
    13801 gatactcaaa tctgtaactt ctggtttgcc gcaggcaaag agacgctcgc agtaaataaa
    13861 agaacctata tttgtgactt tagtcgctgc ggtttgaata ctcgcttata cacgctcgta
    13921 tccaaacctt gctccgaggc cacaaatata ggttctttta tttactgtga gctgtctttg
    13981 gctgctgaag taaagtcaga atttatgttt taaaagattt ggggattttt tagaagt
//
