LOCUS       gnlProkkaIDBPNLIP_44   11127 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IDBPNLIP_44.
ACCESSION   gnlProkkaIDBPNLIP_44
VERSION     gnlProkkaIDBPNLIP_44
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 03:15:54
            Original ID  :: gnl|Prokka|IDBPNLIP_44
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11127
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..591
                     /locus_tag="ctg4_1"
                     /transl_table=11
                     /translation="MNKAGGPTSLAYLRGAKLTRVASAGEKKRMGDVIRLMSRQLGEAM
                     IDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIPKNTNTVTINGAVMVPNT
                     VSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKGSGKKQIEPGCEIIVPGK
                     AKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     protocluster    1..11127
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1813:6127]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1814..6127
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11127
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11127
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             602..1750
                     /locus_tag="ctg4_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             1814..2533
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.5e-15, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2554..3855
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1.9e-12,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.9e-120, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.2e-62, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             3872..4996
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1e-19, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.8e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             5006..6127
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg4_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_6"
                     /sec_met_domain="Aminotran_5 (E-value: 1.5e-30, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        5096..6103
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg4_6_Aminotran_5.1"
                     /locus_tag="ctg4_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             6124..6267
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             6470..7954
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_8"
                     /sec_met_domain="Polysacc_synt (E-value: 1.3e-30, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             7908..9167
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             9176..9925
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             9925..10965
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 gtgaataaag cgggtggtcc taccagtctt gcttatcttc gtggtgcaaa gctgacccgt
       61 gtggcaagtg ccggtgaaaa gaaacgtatg ggtgatgtaa ttcgccttat gagcaggcaa
      121 ttgggcgaag ccatgattga ctctttgggt attcgtgttg aagatacttt tacggttgga
      181 atagatttgg aaaaagcctt gagcaatcct aaaagtaatg ccgatcttgt cttacgtgaa
      241 ggtgatgtga tctccatacc taagaatact aatactgtaa ctatcaatgg tgctgtcatg
      301 gttccgaata cggtttctta tatgaaggga aagaatgtgg attattacct gaatcaggcc
      361 ggtggctgtt ctgataatgc aaggaagagt aagaagttca ttgtttacat gaatggtcag
      421 gtgacgaagg ttaagggtag tggtaagaaa cagattgagc cggggtgtga gattattgtg
      481 cctggtaagg ctaagaagaa agggaacata gctaatattt taggttatgc tacttccttc
      541 agttctttgg gaatgatgat tgcttctatt gctaatttga taaagaaata aatgacctat
      601 tatgattgaa aagcaatctt atcaagaacc gttttctgaa gtggataaaa ggaaagatga
      661 tgaaatggaa atagacttga tggctatttt ttataagatt attactgttc gtggagtact
      721 atgcaaagct gctggagtgg gagtaataat tgctatagtg gtggcattga gcattcccaa
      781 gcaatataca gtaaaggtta ccctttctcc tgaaatgggt aatgcgaagg gaagtaatgg
      841 tttagccgga cttgctgcct cgtttttggg agatggggct ctaatagggg aaagcacaga
      901 tgccttgaac gcttctcttt cagcagatat tgtttcttca actccttttt tattggaact
      961 tttagaaatg gaagtctccg tttctaaaaa ggatgataaa atgactttgg ggtcttatct
     1021 cgatgaagag tcatctcctt ggtgggatta tcttataggt tttccgggca tagtaatagg
     1081 aggagttaaa tcattattcg gagaagatac ggttcctgcc agtggagggc ggcaaggaac
     1141 tatcgaattg acgaaagaag taaatgagaa gattaatttt cttaaaaaga agattagtgc
     1201 atccattgat aagaaaaccg ccataacgag cattacggtc accttacaaa atccgcagat
     1261 cactgcggtt atagcagatt ctgtcgttca taaattacag gaatatatta ttgggtatcg
     1321 aacttcaaaa gtaaaagaag actgtgcgta tttggaacgg ttgtttaaag aacgtcagca
     1381 ggaatattat gctgctcaaa gaaaatatgc ggattatgta gacgcccatg ataatgtggt
     1441 tcttcaaagt gtacgtgctg agcaggagcg tttacagaac gacatgagtt tggcttatca
     1501 gatatatagt caggttgcta atcagttgca ggtatccaga gccaaagtac aggaggaaaa
     1561 gccagtcttt gcagtagttg agcctgccgt tgtacctttg aaaccttcag gtatgggact
     1621 caaaatttat attttattat ttgtgttcct gtccgtatct ggtactctcg tgtgggtgtt
     1681 ttttggcaaa agtctgctgg ctagcttgag aaaagaactg aaaaataagg agatagaaca
     1741 ggataaatga tgctaaaacg tcgtttacaa cattcttaca tcaattaaat tcacttacta
     1801 tattattaaa cgaatgatac gtacagctat gataatggct gcgggcatgg gaacccgttt
     1861 tggccaatat acagaattga tacctaaagg gttcgtcaaa gtgggaggta ttccaatgat
     1921 agttcgttct attgatactt tgttatcatg tgacattgag cgaattgtaa tcggtacagg
     1981 atataaacaa gaagtttatg aagaattgaa gacagactat cctatgcttg aaacctgttt
     2041 tagtcctcgt tatgctgaaa caaatagtat gtatacttta tataatacgc gggagattct
     2101 gggcaatgat gattttttat tgttagagtc agatttgatt tttgagaaac aagcaataat
     2161 gagcttattg gagtgtcctg cggcagatgc aatgctaata actccagtga caaagtttca
     2221 agatcagtat tatgtggaac atgatgataa ttttcgcctt tcttcatgtt ctgtcaataa
     2281 gaataaacta aacgctaaag gcgaattggt cggcatccat aaactatccg gttcctttta
     2341 caaaataatg tgtgctgatt atgcgagtat tgttgatgaa caacccaatt tgggatatga
     2401 gtatgaatta ctacgaatat cttgttctca atctcctgtt tatgtgcata aagtagaagg
     2461 gctgaaatgg tatgaaatcg atgacatatc agatttggaa tatgcagaga aatatattgt
     2521 tccgtattgt taattaaaat aatatatcaa attatgagta agacagttta tattgggatg
     2581 actgcggata ttatgcatcc aggacttatc cgcattatta atgaggctac taaatacggt
     2641 gatgttataa ttggtcttct tacagataaa gctattgcgg agcataaacg ccttccttat
     2701 ctgacctatg aacaacgaaa agaggtagtt cagaatatta aaggcgtatg taaagttgtt
     2761 cctcaagaag aatggagcta tgttgagaat ctcaaacgca ttaaacctga ctatataatt
     2821 catggtgacg actggaaaac cgggccttta cgtgaagaac gtgtgcgcgt atttgaagtg
     2881 atgaatgaac agggaggaaa ggttatcgaa attccatata ctttgggaat taattcatct
     2941 tctttggata aagatattaa ggctataggt acaacccctg atgtacgttt aaaatcactt
     3001 cgtcgtttga taaatgccaa acccgtagtt cgtattttgg aagctcatga tggactatgt
     3061 ggcttgataa ttgaaaatca ggaaatatta aaaggggata agagggaagt atttgacgga
     3121 atgtggtcta gtagccttac ggattcaacc agtaaaggta aacctgatat tgaggcggtt
     3181 gatttaacta cccgattgca agatttgaat aatattctgg agtgtactac taaacctatt
     3241 atttttgatg gagatacagg tggtaaaatt gaacatttcg tatttacagt acgcacttta
     3301 gaacgtcatg gaatttcagc tataataatt gaagataaag ttggattaaa aaagaattca
     3361 ttgtttggta cagatgttat tcaaactcaa gatacaatcg aaggtttctg taataagatc
     3421 aaagcaggaa aggcatctca gattactgat gattttatga ttatcgctcg tattgagagc
     3481 cttatagcgg gaaagccggt aagtgatgct ttagagagag cttttgcata tgtccaagcg
     3541 ggagcggacg gtattatgat acatagcaaa aataagtcgg gtgaagatat aaaagaattt
     3601 tgtttggcgt ttcgaaaaca gtatgctcat gtacctatcg tggttgtgcc tactacatat
     3661 gatcatattt atgagtctga attgtgtgat tggggtgtga atataattat ttatgctaat
     3721 catatgcttc gtgccgctta tcctgctatg atgaatgtcg caaagataat attagagaat
     3781 gaacgtgctt tagaggtgcg cgaactgtgt atgcccataa aagaaatatt ggaactgatt
     3841 ccaggtacta aataaaaaga ggaatatcat tatgttaagc gtagaaaaag tttatgaaac
     3901 gtttctgagt catgacgttg atttttttac aggagttcca gactcattac taaaaaatat
     3961 ttgtgcctat atcacagacc atacttcacg tgagaaacat atcatagctg ctaatgaagg
     4021 tgcggctgta ggaattgctt caggttatta tatggcatca ggtaaggttc ctgtggttta
     4081 tatgcaaaat tccggcttgg gtaatactgt taatcctctg ctgtctcttg cagatgaaca
     4141 agtatacagt tttccaatgc ttttgatgat tggctggcgt ggtgaaccgg gaacaaaaga
     4201 tgaacctcag cataaaaaac agggtgaggt aactttagat ttgttgaaag caatgcggat
     4261 tccttatata attcttgatt caaatgagaa tgatgcattt attcagctcc atgatatcat
     4321 acaatcagca aaaactaaga atattcctca tgcaataatt attcggaaag atgtttttgg
     4381 caaatataaa cttcaaaaag agttcggatg taattatcct ttatctcgtg aggatgcttt
     4441 gcaaatagtt gtggattatc tgcctgaaaa ttcagtggtc gtttctacta ctggcaagct
     4501 ttctcgtgag ttatttgaat atcgagaaat gaaagagcaa ggtcatgaac atgattttct
     4561 cacggtaggc tctatgggac atagttcatc aatctctttg ggtattgcta tagcaaagca
     4621 agatagacct gtttattgct tggatggtga tggagcattt attatgcatt taggggcaat
     4681 tagtaacatt ggcgatttat ctcctaaaaa ctattatcat attttgttta acaatggtgc
     4741 tcacgagtct gtaggaggac agcctacttt aggatttagt ttagatattc cggctattgt
     4801 ccgggggagc ggatataagc atacttatac tgtttgtaca aaagttgaaa ttgaagaagc
     4861 aatgaagcag cttccaaagt tatgtggtcc tgttttgttg gaaataaagg ttaaaataga
     4921 ttctcgggag aatttgggac gtcccacgac tactcctata gagaataagg agcattttat
     4981 ggatttttta aaataaatat attcgatgaa aatagaaaga aaaatattat taaatcctgg
     5041 gcctgccact actactgaca gtgtaaaaat ggcacaagtt gttccggata tttgtcctcg
     5101 cgagaaagaa ttcgcaggta tgatgaaaca acttcgggac gatttggtca gagttgctca
     5161 tgggaatttg gaaaaacata ccgctgtatt attttgtggc tcaggaacca tcaatattga
     5221 tatatgtcta aattctcttc ttcctgaaga caaaagggtg cttatagtga ataatggggc
     5281 atatagtacc cgtgctgtag aagtgtgtca atattatggt ttgcctcata ttaatttgga
     5341 attttccgtt tacgaacgtc ctgatttatc ggtggtggaa aatgtgttgc aagaaaatcc
     5401 tgatatagct atggtttata ctactcatca cgagacgggt acaggaattc tgaaccctat
     5461 tcgcgagatg ggcgctatag ctcataaata tcaggctaaa tttgtcgtcg atactacttc
     5521 ttctttgggc atgattcctt ttgatataga gaaagataat gtggattttt gtatggcatc
     5581 tgctcaaaaa ggacttcaag cgatgacagg tctttctttt attataggca atgaggaaca
     5641 gattaagttt tcaaaaaaat atcccaagcg ttcttactat tgtaatcttt atttgcagta
     5701 tgagaatttt gagagaacag gtgaaatgca ttttactcca ccggtacaaa ctatttacgc
     5761 cactcgtcag gcattaaatg aatattttga agtgggtgaa gaagctaagt ttgcccgtca
     5821 caaaagagtt tttgaggcta ttcattcagg tataaatgaa attggtctta aaagtgtaat
     5881 aaagcgtgaa tggcagtcag gactggttgt ctcagttcaa tacccagaag atcccaactg
     5941 ggattttgag aaaatacatg attattgtta tgagcgtgga tttacgattt atccaggtaa
     6001 gatatcaact gaggatactt ttagaatctg tgctttagga gagatagaag tagatgatat
     6061 tgagaacttc tttaaagtac taaaagctgc attaaatcat tataacgtca cattaccgat
     6121 gtcatgattg cagaaatatt attgaagatt cgtcattttt atttttccct tcgtggtata
     6181 cacttccatc cggaaagtgt tatttctgga gtgcctattc gtagctttcg cttagtaggc
     6241 aaatatggca atattaattt gaggtgatgc attaggagtt ctttattctt ataaaaaggc
     6301 atcggtagtt ataggagata atgtttgtgt agggtaattt gcttttagtg ggagagacca
     6361 tattagaatt gcggtaaggg gcgaagaaga taataaccaa ttagtgagaa tattggaaaa
     6421 atataattga tatcggtaaa tgtagttgtt tttatactgt atttaagtaa tggaaaatct
     6481 aaagcagaaa actgtatcag gaataatgtg gagcgctata gaacgtttct ctttacaagg
     6541 agtacagttt ataattcaaa taatattagc tcgtttgtta ctaccatcgg attatggtat
     6601 gatcgggatg ttagctattt ttcttcaagt cgctcaagta tttatagata gcggttttac
     6661 aaatgcttta atccagaaaa aagatagaac tgaagaggat tttgccactg tcttttattt
     6721 taatattctt gtcgcagtat tattctatgg tatattgttt ttttcggctt ctttgattgc
     6781 agacttttat aatatgccga ctttagttct tgtaattcgt tttatagcat tgtcgttgat
     6841 aataaatgct ttatcggcta ttcacagaac gaaattaatt atttctgtaa actttaaaac
     6901 tcaatctaaa atttcattag gtgcagcttt tatatcaggc gtgattggaa tatggatggc
     6961 ttatgtcggt tgcggggttt gggctttagt ttggcaaact ctcttaaata gtataatttt
     7021 gacaattttg ttttactgtt tagttcattg gaaaccttta catactttct ccaaaagttc
     7081 ttttgaaaga ttattcaatt tcggatctaa attattgatc tcaagtctta tcaatacagt
     7141 atatcgtaat ctgtatacca ttgtaatagg aaaaaagttt tctgttgtag agcttggtta
     7201 ctatacaaga gcagaacaat ttgctatttt tccttccaat aatttaaatg ctttagtttc
     7261 tagagtagcg tatcctattt taagttccat tcaagatgat gataaatgtt tgacaaacgc
     7321 atatcgaaat tatatcagat tatcctcata tataattttt cctttaatgg taggtttact
     7381 tgttttggct aatcctatta ttagtctatt gttaacagat aaatggtctg gggttgttat
     7441 tcttttacag atattatgtt tggattggat gtttgatcat ttgagccaaa ttaatttgaa
     7501 tttattatgg gttaaaggaa gatctgatct gtcgttacgt cttgaaataa taaaaaagac
     7561 gattgctata ttcattcttt ttgtgtcaat tccatttggg cttgaggtga tgtgttgggg
     7621 tagagttatt tactctctga tagcgacata tttgaataca tattatacta attctcttat
     7681 tgatttgacc ttaaagttgc aagttaaaga tgtatttcca agtttaatac tctctttcat
     7741 aatggggggg atcgttttta tatgtatttc tttctttgaa actgatatag taaaaattgt
     7801 gattggatgt attactggga tgtccttcta tattttactt tcttttcttt ttaagctaga
     7861 ttcttttttt tgtattttaa cattgatcat taaaactaaa aacatagatg aaaatattaa
     7921 aaaagatttt tcaagtaata gtaaagataa ttaaccattg tgtgccagtt gatagtagat
     7981 cattgtattt tattcctcat cctaattgta gaacagataa atatgatatt ataaattatt
     8041 cgtcagataa tgttctcgtt ctgttaaatt atttgctaaa aaaagatagt gctgaatatt
     8101 ataaaatata tgttgaaatt tatgattctt ctcgtatttc agaatatcaa gaatatattt
     8161 atggcataaa tcctaatatt aggtgtactt ttttatgtgc atgtgttgga cgttttttct
     8221 ttaataaagt atcttttaag gatatgttgt atgccttttt ttgtttttgt agagcaagta
     8281 aatgttttac agctactttt tattatgatt tttcatttaa aaaacgctct caacagatta
     8341 tttgtttggg gtattatact ccattcaaag atgattatca tatgggagat cattcttatg
     8401 ataaatttcg taatacaaca tgtaactcat ttgattactc tattgctact tcttgtttaa
     8461 gtgctagaat aatttcaata gattgtggaa tctcatatga taaattcaaa gtcttaggat
     8521 ttcccagaaa tgatttgttg atatcgaaaa ataattgcaa tgttattaaa agagaaattt
     8581 cgaaatttgc gggatatgat gtaactaaat atatagttta tactccaact tttcgtgatt
     8641 atgagactgt tactgaaggt aatttgcgtt caatactcgg atatgttgat tgtgatttgt
     8701 tgaagttatc gaaaatacta ttgaagttta atgcggcttt aattcttaaa ttacatcctt
     8761 tgcagaataa aacagtctta aaaaaagatt tacccaaagg tatacttgtt tttgaacaaa
     8821 catataaata tggattgtat gatcttttgt cattttcaga tggaatgatt actgattata
     8881 cttctaccta ttttgatttt ttattggtaa ataagccagt catatttaat ttctacgata
     8941 ttgaagaata tcgtagagta agaggtttct catttgagcc aatagaattt ttttgtgcag
     9001 gtgatattgt ttacaattat aatgaattga tagatgctgt gatgggactt ctggctggga
     9061 aagatattca tgctgaacat cgacgtcata tttctttatt gatgaatcaa tttcaagatg
     9121 ataattcaac aaagagaata tgtgacatat ttttaaatga aatataataa ataaaatgaa
     9181 ttatgcattt gtggtgcagg cacgtttagg ttctacacgt ttgcctggaa aaatattgaa
     9241 acctttctat ggtaatcaat cgattcttga cttaatggtt cataagcttt ctgctatatc
     9301 gaatattcca gtaattattg ctacaacaaa ttctgttatc aatgaaccta ttgaaaagaa
     9361 ggcacttgca ttaggggtaa agtgcttcag aggtgaggag aatgatgttt taaaacgatt
     9421 cattgatgtt gctgaatatt ttgatataca gggtatattc cgaatatgtt ctgataatcc
     9481 atttttagat gtacatgcgg caaggcaatt ggtcgaaata gcaatgaaat cttgtaacga
     9541 ttatataagt tttgatattg atggtactcc atcaattaaa actcatttcg gtttttgggg
     9601 agaatttgta acgcttgatg cgctgaagcg agttatagga tttactgatg atttattgta
     9661 tcgtgaacat gttactaatt atatatatag tcatcctgaa ctttttaata ttcaatggat
     9721 ttcaggatct ccagtcgtgt caaaacatca taatattcga ctcacgattg atacgttaga
     9781 agatttttct gtagcacaga gaatatatag ggatttacaa gaaaaaagag tggaaatatc
     9841 gatagaagtg attgtagact atgttcgaag acatgcagaa tacattcaac tgatgaaaca
     9901 acaaataaaa aaaaattcta aataatgaag aatacttata ttattggtga aatagggcag
     9961 aatcataatg gttctgttga cttggctaag ttgattattg aattaatctc acgacctgta
    10021 catgaggatg tttttggtat ggatttcatg ccaatgaatg ctgttaaaat gactaaaaga
    10081 gatttatcag aagaattggc tgtttctcaa atgaatcaaa tatatgacaa tcctaattct
    10141 tttgggcgta cttatggtga acatcgtgct tttcttgagc ttgatgatca agcgcatttt
    10201 gagatttata aatatgctaa gtcattagga ttagatttta tcgagacgtt atgtgccaaa
    10261 ggatgtctgt ctttgcttaa actgttcaca ccggataggc taaaagttgc tagtcgtgat
    10321 ttgactaact taccattgct tgaagcatta gcagaaactc atattcctat tatattatcg
    10381 acaggaatgg ctggtcaaag agaacttgac aatgcattag atgtgataac gagatatcat
    10441 agtaatatag ctattctaca ttgtgtatct cagtatccaa ctcatccaaa taatttgaat
    10501 ctacgtacaa taacatattt gaagaagcat tacaataagt ttgagatagg tttttctgat
    10561 catacaatag gtatttctgc tgctacagct gctgtagcga tgggagcgga aattatagaa
    10621 aagcatgtaa caattgatcg gcatatgaaa ggaacagacc agcttggctc tttaggtcca
    10681 gatggggtta atcgtatgat tcgagatatt cgcatagcag agtgttggct tggtactgaa
    10741 gatctttata tagaaaaagg ggtggagaag tctaagataa aacttgaacg ttctattgcc
    10801 actcgaaaat atattccagc aggtagtatt attcaagagt cggacattca tttactgagt
    10861 cctggtgatg gttataaatg gatagataaa aaaaatgtaa ttggtcattt tgctaaacaa
    10921 gatatatcag cgaatgaaat aatatatcct gattttattg aatagatata ttcctactgc
    10981 aacttgtatt acggtataga gtactgcctg ctataagcta agtagtgatt aataaataag
    11041 ggtaaaatac taaaaaaatg aaagagataa agcttatact tacagatatt gatggcgttt
    11101 ggactgatgg cggaatgttt tatgatc
//
