LOCUS       c00041_gnlPro..        16626 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GICFJEBL_421.
ACCESSION   c00041_gnlPro..
VERSION     c00041_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 02:59:49
            Original ID  :: gnl|Prokka|GICFJEBL_421
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16626
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16626
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9889:13447](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(9890..13447)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16626
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16626
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             231..1457
                     /locus_tag="ctg41_1"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
     CDS             1790..4543
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_2"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             4571..4903
                     /locus_tag="ctg41_3"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(4866..6152)
                     /locus_tag="ctg41_4"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             6625..7851
                     /locus_tag="ctg41_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7848..8678
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg41_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             8706..9566
                     /locus_tag="ctg41_7"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(9577..9765)
                     /locus_tag="ctg41_8"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(9890..13447)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_9"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(13481..14686)
                     /locus_tag="ctg41_10"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             14866..16020
                     /locus_tag="ctg41_11"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYLLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
ORIGIN
        1 ttagttcact gcaactctac ttttcaaata tacacttata ttttgttgtg atatttaata
       61 ctgcaaatgt aaatgtgtca aaagcaacta aactctcctc cttcctgaag gaggggaatt
      121 tagttgcttt tgacacatct tcttttctgt ttcttatttc agtaaatgtc ccccttccct
      181 gtgttttgat ttactactta atctgttaat tattagaatg ataataacag atgttctttt
      241 ttctaattgt ccccctcttt cttgccttgt tttataagcc gattgcctat ctttgcggca
      301 ggtttttaaa taataaatca aaaagagaaa actactttat gaaacacatt tcgaacttcc
      361 tcagatcaaa aagctggaac gtatttttgt ttttatatct tgctcttcct ttgtttgcgc
      421 aaaaggaata taagatcgat caggtatctg ttgttaatgt aggcgatggc agactgttgt
      481 ttcaggaact gaaaacggaa aaagcattga atggcgaaca tcgcatcata gatggttatc
      541 attccgccta tgtgctggca tcttttaaag atggttttta tgatggcgga tacaaagaat
      601 atgtggacaa tatattaata acggaaggaa gttataaaga agggcggaag gatggcctct
      661 tcaagattaa ctccaagttt gacggtaagc tgaaagaaga aaagtcctat aaggaaggta
      721 agctggacgg tacgagcaaa agttacttta ctaccggaaa agtggaaagt gaaagaaact
      781 tccggatggg gaaagagcac gggaagcaac tgtcgtacga atctgacggt actttgcgga
      841 aagagcataa ttacaaggac gggaagcagg taggcaaaca gtatactttt ctgaaaggta
      901 catatgattt gtatgagacc gtttatttca atgaagaagg ttttcaggac ggtgaatatt
      961 cgtccgtgtt tacgtttggc tcgccacgta tactgggtag ttataagaat ggaaagaaga
     1021 atggtcgttg gactactttt gctgaaagcg gagatacgct gatgattgaa acctatctgg
     1081 atggaaaaga agatggactc catgtctcat ttgccaacgg aagtggggta aggcagaaag
     1141 aatattatat gaagaacgat cgtaaagacg gtttataccg tgaatataat ttggaaaatg
     1201 gtgaattgag atatgaagct acctatcagg ccggcagatt gcatggcaag gaacgacggc
     1261 tgatagtgag caaccgcttt gattattggg aaacttctac ctatgtgaac ggaaggcaga
     1321 acggaccgtt cgaagctcgt tatgtaaaga atgaccagct tcgtgaatgt ggggaatata
     1381 agaatggtca ccgtgtagga cgatggaaac gctacactat tgatggtaaa ctggaaaagg
     1441 aatgggatga aaactaaccg gtagatgaaa ggtcagagca taaaaaaagg agcaacgcct
     1501 tgctccaacc tttgttaacc ttaaatctaa tactatgaaa aacacagtgc aaagatacgg
     1561 acttctgtga aatctgcaaa ttatccaagt aaaacgctat gttttataac attgattaag
     1621 tgtttgtttt acgctttata cttttgttaa tactttccga tggtctgaaa gaggactgct
     1681 ttccttcttt ttagaataat aaatagctga agttagagaa ctttacagta ttatttctta
     1741 tttttgttct taattggatt acagaaagaa ctatgaaatg atgagatgga tgaagacgat
     1801 gagatatctg aagtggatgc tggtgctgtt tggtttaatc gggatgacgg cttgccggca
     1861 ggatacaccc cgttttcgta ttggggtggc tcaatgcagc gatgattcat ggcgacataa
     1921 gatgaatgat gagattcttc gggaagcgat gttttataat ggtgtttcgg tggaaatccg
     1981 ttcggcaggg gatgataaca gtaagcaggc ggaagatgtc cattatttta tggacgaagg
     2041 agtcgatctg ctgattattt ccgctaacga agctgctcct atgactccga ttgtagaaga
     2101 agcttatcag aaaggcatcc ccgttattct tgtagaccgg aagattcttt cggataaata
     2161 tactgcctat atcggagccg ataattatga aatcggtcgt tcggtaggaa actatattgc
     2221 ctccagtctg aaagggaagg gaaatatagt agaactgaca ggattgagcg gttcgactcc
     2281 tgcaatggaa cggcatcagg gatttatggc tgccatcagt aaattcccgg atataaagct
     2341 gattgataaa gcggatgctg cgtgggaacg tggtccggca gagatagaaa tggatagtat
     2401 gcttcggagg catcctaaga ttgatgctgt gtatgcccat aatgaccgta tcgctccggg
     2461 tgcctatcag gcagcaaaga tggcagggcg ggagaaggaa atgatttttg tcggcataga
     2521 tgccttgccg ggtaaaggaa acggactgga actggtactg gacagtgtgc tggatgccac
     2581 ctttatctat ccgaccaatg gcgataaggt actgcaactg gctatggaca ttctggagaa
     2641 gaaaccctat cccaaagaaa cggtgatgaa taccgctgtt gtggaccgta ccaacgcaca
     2701 cgtcatgcag ttgcagacca cacacatttc cgaactcgac aaaaagattg aaacgctcaa
     2761 cggacgtatc ggtggctatc tctctcaggt agctacacaa caggtcgttt tatacggcag
     2821 tctgattatc cttttattgg tagccggctt attattggtc gtttataaat cactccgctc
     2881 taagaatcgc ttgaataaag agctttttaa gcagaagcag caattggaag agcagcgtga
     2941 caaactggaa gaacagcgtg accaattgat acagctctct catcaactgg aagaagctac
     3001 ccatgccaag ctggtctttt tcaccaatat ttctcacgac ttccgtactc cgttgacatt
     3061 ggttgccgac ccggtagaac atttgttggc ggacaagaca ctgagcggag atcagcaccg
     3121 gatgctcatg ctgattcagc ggaatgtgaa cattcttctg cgtctggtca atcagattct
     3181 ggatttccgt aaatatgaaa acggcaagat ggaatatact ccggttacgg tggatgtcct
     3241 ttcttctttc gaaggatgga atgagtcttt tcaggcggca gcccgtaaga agcatatcca
     3301 tttttctttt gatagtatgc cggatacgga ttatcataca ctggcagaca tggagaagct
     3361 ggaacgtatt tatttcaatc ttctgtccaa tgcctttaag tttacaccgg aaaacgggaa
     3421 aatagccgtc cgtctgtctt cccttagtaa agaggacaag cgatggatac gtttcacggt
     3481 ggcaaatacc ggttctatga tttctgccga acatattcgc aatgtattcg accgtttcta
     3541 taagatcgat atgcaccata ccggttcggg aatcggactg gcattggtaa aagccttcgt
     3601 agaaatgcac ggtggtatga tctccgtaga gagcgatgag aaacagggca cggtctttac
     3661 cgttgaactg cctgtacagt cttgtgaggc tgttgctgcc gaaccggata ccacccttgt
     3721 ttctgcggat tcccgtacaa cagatgttct attggcggaa gaggaagaac tggaaaaagg
     3781 atatgactct tccaaaccgt ccgtactgat tattgatgat aatgaggata tccgttcgta
     3841 tgtccatacg ttgttgcata cagactatac ggtgattgaa gcggcagacg gctccgaagg
     3901 aatccgtaag gctatgaagt atgttccgga cctgatcatt tctgatgtga tgatgccggg
     3961 cattgatggc attgaatgtt gccgccggct gaaaagtgag ttacagacct gtcatattcc
     4021 ggttattctg ctgacagcgt gttcactgga cgaacagcgt attcagggat atgacggtgg
     4081 tgcggattct tatatttcaa agccgttcag ttcacagctg ttgctggcac gtgtccgcaa
     4141 tctgatcgat tctcaccgtc gtctgaaaca gttctttggt gacgggcaga cattggcaaa
     4201 agaagatgtc tgcgatatgg acaaggattt tgtagaaaga ttcaagtcat tgattgaaga
     4261 gaaaatggga gactccggtt tgaatgtgga ggacttgggc aaagacatgg gactaagccg
     4321 tgtgcagctt tatcgcaaga ttaaatcatt gactaactac tctccgaatg aattgctccg
     4381 tatcgcccgt ttgaagaagg cagcttcttt gcttgcttct tcggacatga ccgtagcgga
     4441 gattggttat gaagtcggtt tcagttcacc ttcttatttc gccaagtgct ataaagagca
     4501 gtttggagag agcccgacag atttcctgaa aaggaaagga tgatttcatt gatatcgtaa
     4561 agagggatat atgaaagatt ataaagtaga taaagagagc ttttccgaat cctttcggaa
     4621 ggaagtgtac gaagtcgtat cccagatacc tgtgggaaaa gtatctactt atggaggtat
     4681 tgctttgctg ttgggggcac cccaatgctc gcggatggtg ggacgtgcat tgaaagaagt
     4741 gccggatgaa ttatccattc cctgccatag agttgtaaat tccaccggaa ggctggtgcc
     4801 cggttgggtg gaacaaaaac aactcttgct ggcagaagaa gtttctttca aagctaacgg
     4861 atgcgttaat ctgaaagaac atttgtggca cgtggatgaa tgaaggatgc aaggaaggta
     4921 agccatatca tccgtatcca tacaataaag aaaacccata catgaagcca taaggtcctg
     4981 gtaatgaaat ctctgatggg tacagggacg aatatgtcga taggaacgat acataacagc
     5041 acaaaacagc accaaaatag aatcttgtct gttgcggtac gtgttggtct gctccaatac
     5101 cagagcatga aacctgccaa tgcgataata taggtatgct tctcggcgga gtcactcagt
     5161 aatactaccc agcccatgag aatgcccaaa gcctgggcac ggaaggcaaa agacgaccat
     5221 ttgcggaaat tccccaaaaa gagcagagtc agcaagccga gcattcctat ctgaagtgca
     5281 cggaagtgtg gcaatgtcca tgctgcaatg gggcgggcat agaaaaatga atcataagct
     5341 ccggcggact gatgaacagc aagactatgg caccattctt cataataggg gagcaaatct
     5401 gcaggagcta tttttattaa cggtaatgca agcaatacaa tgcccattgt aacggcatag
     5461 ccaaagttac gccatacgtg aggatagcac agcaacaatg ccagttcgaa aattccatat
     5521 actttggtac atcccgaaat catgattaac agaacagcca gaaatccacg gtctttttcc
     5581 aataacgtat aggcgaataa gaataaatag gctaccgtta tgttatactg aaatgaaagt
     5641 aaactttgtc ctaaaatcag taacagaaaa aggaacatac ggcatttctg ctgctgggtg
     5701 aattgttggg gcagcgtgaa gatcgccata aagaacagcg aataattgaa tagattccac
     5761 gcgaaaggtc ccagccatgc aggcagatac gcaaacggag cgaacaatac cgtgaaaact
     5821 ggagaataaa ggaagtagcg tccgtgagct tctacaaatt cagttgtgta tgggctgatg
     5881 ccttgccaga agaattgagt agcgtccgag aagaccataa agttttgatg ccgtcctcgt
     5941 ataaattcga gcagagtcac tataaaagcg agcaggaaac ctatcatgta gagattccgc
     6001 cggctataga aaaacggcat tttggggttc tttttactaa ggaactgtac ttggcttttg
     6061 tcgtctagtg tggcagtacc tgtttgtttt tcttttgttg tgtaatgaca attatccttc
     6121 cccaggaaaa ttgtaatagc cctgttgaac atataaatct agtttagtta ttgacgccaa
     6181 atatacggtg tttaagtgaa atattcaaac ttattttata tttatctgcc ggtttgttct
     6241 attttgctga gtgatagggg aatattaccc ggaaactttc catatcatta caaataaagc
     6301 cctctgtatg ccccggattt tgaatataat ttgtatgttt aatccgtttt ttgtatcttt
     6361 gtgccagcaa gatactggaa caggctgttt ttatacataa aaatgctatt ttttgctatt
     6421 cgttgaaagg attatcttat caaattctat tcctttttta attactcagt ctgtcaataa
     6481 tcattttatt aattatttcg ggattcattg ttatttgtcc cttatttaaa tcagaacttt
     6541 atacgatata aagaaagatt cctgttatcg tttgttcttg tcttgctgtg tatattattt
     6601 taataaccta aaccatttta ttgtatgagt aaaatagaaa ttaaagatct ctatctggtt
     6661 tttggcaatg agaagcagaa ggctttgaag atgttgaaag aaggtaaaac aaaaagtgaa
     6721 atattgaaag cgaccggatg tacagttgcg gtgaaagatg cgaatctttc cattaatgaa
     6781 ggcgaaatat tcgtcattat ggggctgtcc ggtagtggaa agtccacttt actccgctgc
     6841 atcaaccgtt tgatacgccc tacttccgga gaagtgatta tcaatggaac agacatagcc
     6901 aaagtgtcgg ataaggaact gttgcagatt cgccggaaag aactggctat ggtctttcag
     6961 aacttcggtc tgcttcctca ccgttctgtc ttgcataata tagctttcgg gctcgaacta
     7021 cagggagtaa aaaagggaga acgggagcag aaagcgatgg aaagtatgca actggtgggg
     7081 ctgaaaggct acgagaatca gatggtaagt gaactgtcgg gtgggatgca gcagcgtgtc
     7141 gggctggcgc gggctttggc caataatccc gaagtcctgt tgatggatga ggccttctcg
     7201 gcactcgatc ctttgatccg tgtgcagatg caggatgaac tgctgacttt gcagtcgaag
     7261 atgaaaaaaa cgattgtctt tattactcac gacctgagtg aagcgattaa attgggtgac
     7321 cggattgcta tcatgaagga tggagaaatt gtacaaatcg gtacatcgga agaaatcctg
     7381 accgaacctg ccaacgctta tgtagaacga tttgtggaga atgtagatcg aagcaagatt
     7441 ataacagctt cctctgttat ggtagataaa cccatagtgg cacgtttgaa gaaagaaggc
     7501 ccggaggtgc tgatccgtaa gatgcgcgaa cggaatctga ccgttcttcc ggtagtcgat
     7561 tccaataatc tgttagtagg agaggtgcgg ttgaatgact tgctgaaact acgaaaagag
     7621 caaatccgct ccatcgagtc cgtagtaagg catgaagttc attcagtgct gggtgatacg
     7681 gtgctggaag atattcttcc gttgatgaca aaaacgaact cgccaatctg ggtcgtaaat
     7741 gagaatcggg agtttgaagg cgtagtgcca ctttcctcat tgatcatcga agtaacggga
     7801 aaagataaag aagaaattaa tgaaatcatt caaaacgcaa tagaattatg ataaatatcg
     7861 gacaatatat agagactgcc attaattggc tcacagaaca ttttgcttcc ttttttgatg
     7921 ctctcagcat ggggatcgga ggattcatag acggttttca gcacgtactg tttggaatac
     7981 ctttttatat cacaattgca gtgctggctg cgctcgcctg gtttaagtcg ggtaagggga
     8041 cagccgtatt taccctcttg ggtttattgc ttatttacgg catgggcttt tgggaagaaa
     8101 cgatgcagac attggcattg gtactttctt ccacttgtct ggcattgctt ttaggcgttc
     8161 cgttgggaat ctggactgcc aacagtgatc gttgtaacaa gataatgcgc cctgtcctcg
     8221 actttatgca gacaatgcct gcctttgtct atctgattcc tgccgttcta ttcttcggat
     8281 tgggaactgt gccgggagct tttgccacca tcatctttgc aatgcctcct gtggttcgtc
     8341 tgaccggtct gggcattcgt caggttccta aaaacgtagt agaagcctcc cgctcttttg
     8401 gagctactcc ctggcagctt ctttataagg tgcaattgcc tttggcgttg cctactattc
     8461 tgacgggaat caaccagacg atcatgatgt cactttcgat ggtagtgatt gctgccatga
     8521 tttctgccgg aggattggga gaaatcgtgc tgaaaggtat cacccaaatg aaaatcggac
     8581 tcggatttga aggcggtatc gcagtcgtga tattggcgat cgtgctggac cgcatcactc
     8641 agggtatggc agataacaga aaaagtaaaa agaaataaga atcacaccaa agaaaggaat
     8701 aatcaatgaa taagataaaa atgattgcgg caatgtttat tgccggcata ctcttaacct
     8761 tcgtttcctg cggagacaac ggaaagagta agaagataag tatcgcttat gccaactggt
     8821 cggaaggtat tgcaatgaca aaccttgcca aagcgatttt tgaagatcag gggtacgatg
     8881 taaagttgct gaatgccgac cttgcaccta tatttacctc tatctcccgt aagaaagcag
     8941 acgtatttat ggatgtctgg atgcctgtca ctatggaaga ttatatgaaa caatacgggg
     9001 ataaactcga agttatcggg gatatttatg atggtgcccg tatcgggctg gtggttccgg
     9061 attacgttac gatcaactca atcgaagaac tgaacgcgga aaaggaacgt ttctccggtc
     9121 agattgtcgg tattgatgcc ggagccggta ttatgaaagc taccgatcag gccatcaaag
     9181 actatggatt ggattataaa ctgatgactt cgagcggacc tgccatgact gcttccctaa
     9241 agaaagcgat tgataagaaa gactggattg tcgtgacggg atggacgcct cactggatgt
     9301 tcgaccgttt caagctgaaa gttcttcagg acccgaagct gatatatgga aatacggaat
     9361 ccattcatac catagcatgg aaaggtttta gcgagaaaga cccttttgct gccgaacttt
     9421 tgggcaacat tcgtctgaca gatgcggaaa tcagctcctt aatgactgct ctggaagagg
     9481 cgcagacaac ggaaagacag gctgcccgtc aatggatgga agaacatcag gaactggtga
     9541 acagttggat tcctgagaaa gattgatatg caaacactac ttcaaccatc ccgccattct
     9601 ttctttacca tagaagtagt agaaaagtag tcccagccag ctggtaagaa cgattaatac
     9661 aatcgctata agtcttttct ctacagccgc atttatattc caaatctcta tggcagctct
     9721 gaaagtcagt atcaaaccga taatccaaat aacaaatccg atcatatctt tagagtttta
     9781 atgaatatct tcgtgagaag taatcgttac ttctaagata taaacaaaaa aggcaggaat
     9841 ctgtttccag gattcctgcc ttttattatg tacaaagtat ttctacttat tattcagctg
     9901 tatcagctcc ccagttttct ctggcaagac gtttgtagct gttgtaacgc catttagcgt
     9961 tttcttcagc agctttaaac agttcttcag cttcagcagg atattgtttc attacagaag
    10021 cgtaacgaac ttcacccttc aagaaacctt ggaagtcttc ccagttaggt tctttgctat
    10081 ccagttggaa cggattcttg ccttcttctt ccaaagcagg gttgtaacgc cacaagtgcc
    10141 agtaaccgca cttaacagcc ttttcttctt cttcctggct cttacccata ccggctttca
    10201 gaccgtggtt gatacatgga gcgtaagcga tgatcagtga tggtcccgga tatgcttcag
    10261 cttcacggat agctttcaga gtctgagcct ggtcagcacc catagcaatc tgagcaacat
    10321 atacataacc gtaagtagta gccatcagac cgaggtcttt cttacgtaca cgcttacctg
    10381 cagcagcaaa cttagcgata gcgcctaccg gagtagcttt agaagactga ccacctgtgt
    10441 tagagtaaac ctcagtatcc aatacaagga tgttaacgtc cttaccggaa gcgattacat
    10501 ggtcaagacc accgtaaccg atatcataag aagcaccgtc accaccgatg atccattggc
    10561 tgcgtttaac aagatattgt tgcagatcag cgatttgctt gcagtggttg catttatctt
    10621 tagcagcttc taccatcgga atgatctttt cggccagttc cttagtcttt tctgcatcca
    10681 gcatattgtt gatccattca gcaaatactt ctttgtattc agccgggcag caatcagaag
    10741 cgatagcttc gttcattact ttcaccagac gggcacgcat cttttcgtta gccagttcca
    10801 tacccagacc aaattcacag aagtcttcga acaaggagtt agcccatgca ggaccgtgac
    10861 ccttttcgtt catagtgtac ggagtagaag gaactgaacc ggagtagata gaagaacatc
    10921 ctgtagcgtt agcaaccatt tcacggtcac cgaacaactg agaaatcagt ttcacgtacg
    10981 gagtttcacc acaaccggag caagcgcctg agaactcaaa caacggagtt gcgaactgag
    11041 agttcttcac gttagccttg atgtctacca ggtgttgttt gctcttcacg ttttcagcgc
    11101 agtaagtcca gttatcagct tcggccaact ggctttcaag gtgtttcatg gtcaatgcct
    11161 tgccaccctt cttcggatta cccggacaga tgtcggcaca gttaccgcaa cccagacaat
    11221 cgagaacgtc tacctgaata cggaatgtca taccatcgaa tgctttacct acagctttca
    11281 gttgctcgaa cttagcaccc ttctgctctt cagcatcgag tacgaacgga cggatagaag
    11341 cgtgaggaca aacgtaagca cacttgttac actgaataca gttttcagca ttccattcgg
    11401 gaacgaatgc agctacacca cgtttttcgt atttggaagt accttgatac caagtaccgt
    11461 cttcgatacc cttgaatgca gataccggca gcaagtcacc gtcctgtgca ttgatcggac
    11521 gaactacttc gttgatgaaa gcaggatcat tgttttctgc ttttgcatca tccggcaggt
    11581 tagcccaagc aggatcgaca gtcagagtct tgtattcacc accgcggtct acagcagcgt
    11641 agttcttgtt aacaacgtct tcacccttct tgccgtaaga cttaacgatg aatttcttca
    11701 tctgttcaac agcttgatct acagggatta cgcctgtgat acggaagaat gcagactgaa
    11761 ggattgtatt ggtacggttg cccaaaccaa tttccattgc aatctgagtt gcgttgatat
    11821 agtatacaga gatgttgttc tgtgcaaagt atttcttcac cttgttaggc aggttcttag
    11881 ccagttcttc gccttcccag atggtattca gcaagaaaga accgttctta cgcaaaccac
    11941 gtgttacgtc gtacatgtgc aggtaagcct gaacgtgaca agcaacgaag ttcggagtat
    12001 ttaccaagta agtagaacgg atcggagtat caccgaaacg caagtgagaa caagtgaaac
    12061 cacccgactt cttggagtcg taagagaagt aagcctgaca gtgtttgtcg gtgttgtcac
    12121 cgataatctt aacagagttc ttgttggcac ctacagtacc gtcagcaccc agaccgtaga
    12181 atttagcttc gaacatacct tcaccgccca gagcgatttc ttctttctga ggaagagaag
    12241 tgaacgtaac gtcgtctacg ataccgatag tgaagtggtt cttcggcatt ggcatagcca
    12301 agttttcgaa tacagagatg atctgtgccg gagttgtatc ttttgaaccc agaccgtagc
    12361 gaccgccaac gataacagga gcattttctg cgccatagaa gcagtcttta acgtcaaggt
    12421 aaagaggttc gccgttagca cccggttctt ttgtacggtc aagcactgcg atgctctttg
    12481 cagtcttggg tacagcagcc aggaagtgtt tagcagagaa cggacgatac aagtgtacgg
    12541 caaccatacc tactttttcg ccgtttgcta ccaagtggtc gatagcttcg cgggcagctt
    12601 cagttacaga acccattgcg ataattacgc gttctgcatc ttctgcaccg tagtaatcga
    12661 acaaaccgta tttgcggcct gtgatcttgg aaatttcgtt catgtattct tctacgatag
    12721 caggaactgc ttcatagtag ttattgcatg attcacgatg ttggaagaag tggtcggggt
    12781 tttcagccat accacgggca accggcttca tcggattcag tgcacgggca cggaattcag
    12841 ccaaagcttc ctggtcgatc agcggagcga ggtcgtcgtt ttccaacatt tcgatcttct
    12901 ggatttcgtg agaagtacgg aaaccatcga agaagttcat gaacggaacg cgtgatttga
    12961 tagtagccag atgagcaaca cctgccaaat ccataacttc ctgtacagaa ccttctgcca
    13021 acatagcgaa gccggtttga cgagctgaca ttacgtcctg atggtcaccg aagatacaca
    13081 atgcgtgaga agccagtgta cgagcagaaa cgtggaatac acaaggcaag aattcaccgg
    13141 caatcttgta catgttaggg atcatcaaaa gaagaccctg agaagcagtg taagtagtag
    13201 tcaatgcacc agcctgaaga gaaccgtgaa ctgcaccggc agcaccacct tcagattgca
    13261 tttcctgtac caatactgtt tcgccgaaga tgttcttacg tcctgcggca gcccattcgt
    13321 ctacgtactc agccatagtc gaagaaggag tgatggggta gatagctgct acttcagaga
    13381 acatatacga gatatgtgct gcagcttggt taccatcaca tgtgatgaat ttcttctgtt
    13441 tagtcataac taaattaaat atttaagtaa ataaatcttt ttagtataag aatccgaaca
    13501 tccaaagagg tatttggttg ccgcggccta tctcagcctt ttgcaacgca tacgtcacgt
    13561 ccgggttatt ctttattttt gtaccttccg cacaaatttt gaacggcatc acttcgtcta
    13621 ccatgaaaga gacgttttta tctcctttat gtaccttatg gtctttccat aaagtgttaa
    13681 cgaagaacgt gtcgagtaca tcctgttctt ccactttcac cggataaatg gagtacatca
    13741 ggttagagtt gtgcatcata atctttgacg gtttctttgg gaattcttct cctttcgggt
    13801 aaaccagatt aatcagacgc gcgtctgcca gatacttgat atagttcatt accgtagcgc
    13861 gggatgtctg tacgtcactt gccagttggc tcacgttcgg agctttcggt ccgtccacag
    13921 ccaacaaata tagtaatttt tttatctttg aaagatattt cagctcaatt tgtttgatca
    13981 gcaagatatc cacttctacc atcatgttca ttgttttcag cagattctcc gagaaattac
    14041 gtttttcaag gaagaaaggg tagaaaccat gatgcaggta atcctgaaaa taatccagcg
    14101 gtcgtacttt ggaaagtact cctttggcta tctgttcatg tgtactgagg atttcttcga
    14161 ggctgtatgc ccggaatttc attcctgtct gcaggttcag aaattcacgg aaagagaatc
    14221 cgcgcaggtt ataacttttc gcaatgtcac gcaattcgag gttttcctct ttgagtcgca
    14281 tgacggaaga accggtgaag acaatcttca ggctggggaa acggtcatag cacattcgta
    14341 gctctttgct ccattcggga tgtttgaaca cctggtcgat cagcagtact tttccgccac
    14401 gtttctgaaa ctcgttggcg aagtcaacaa ggctgtgacc ggagaaataa aagttgttca
    14461 tattgatgaa cagacaggaa cggtcggtgc cgaatttctc tttggcgtac tgcaggagga
    14521 aagtggtttt tcctacgcca cgtgtccctt tgataccaat cagacggtca ctccagtcga
    14581 tctcgtccat aagatcgcgg cgaacggggg cattggtgtg ctcaacgagg taggcgtgtg
    14641 tgcgatagaa tgattccatt tcgtttcttt gtttttcggc tggcaaatat agtgcttttt
    14701 ttaggatttg caaagtagag atagcaaaaa tgtgctttaa tttataagtt tctctttatt
    14761 gtgtaagttc ctgattattt cctgtatata tttgcagaat aatgtgttga atccatcttt
    14821 gacatgacga aaagacctgt ttatatattc aatccggagc atgatatggc gttggcaagc
    14881 ggtgagacga actatatggc gccggcttcc gcccgacaga tggcgagtga cctggcgttg
    14941 cttcctatgt ggtatgccga agcgggaagt gcggtgcttg caccgtctgc ttataatgcg
    15001 gacttcctga aaacaaagag tgaacttttg ggcatggatg tggccttgtt gacggaaccg
    15061 gaagtggctg acggtaaaga ccggaagttc tctccgtggg ggtgggaccc tgctttgcgg
    15121 aagcgtttga tgacattggg ggcagatcag acggagctgc cttctgcgga ttatatgaat
    15181 attctgagag agcattcgca tcgtctgcag gcggtaaagt tgttgcctgg gttgcggttg
    15241 aatgaatact tctgtggaga atctttttat ttgagtactt tggcggagtg cagtgcgttc
    15301 gtcgaagggc gggaagcgtg cttgttaaaa gctccgcttt ccggaagcgg gaaaggattg
    15361 aattggtgta aaggcatatt tactactttt atttccggtt ggtgtgcccg tgtcgctgct
    15421 tctcagggtg gggtggtagg cgaacctata tataataagg tggaagattt cgctatggag
    15481 ttttatgctg acgggagagg aagggttgtt tttgccggat attcggtctt ccacacgggt
    15541 gggagtggga tgtatgcagg gaatgacttg ctgtctgacg agaagattct gcagaaacta
    15601 tcggcttatg tgccacaaga agaatttatc aggctgcgga ctcgtttgga agaagaattg
    15661 tcagctttgt tcggtggctt ttatcatgga tacttgggag tggatatgat gatttgtcat
    15721 tttccggatg aagcgcctgt ttaccggatt catccttgtg tcgaaattaa tctgcgaatg
    15781 aatatggggg tggtggcatg gctcttgacg gatcgttatt tggctgcgga tgcggaagga
    15841 gtttttcgga ttgattatta tcttttagcc ggtcaggctt tggaggaaca tcggcagatg
    15901 tcggcttcgt tccctttgtc cgtagagaat aatcgggtgt gtgccggata tttgccgtta
    15961 gtaccggtga cgcctcaaag ccggtatcgt gcgtttcttt tgcttactct cccccagtga
    16021 aaaagatagt gcttttgctc tcatgctcta acagttcgtc tgtatccctt tattcatcga
    16081 tgttttagct gttagagatc cagtggtagc agagtgagag caaggacttg ctctcactct
    16141 gcatcgtcct gataaatacc gtttttactg tgttattctt tgatttacag gatgttaata
    16201 tctgatatct caactgttaa cgtttgattt ctcagatatt aataattgag aaatcaagta
    16261 ttaaggactg ataatttatg tattattgac tgatatatga tttaatgttt tcagagagag
    16321 cagtactatt gaagtagctg atgcgttcaa tgtgattgga acatgcggtt aagtcaatca
    16381 aatcaacagt agtttcagat agtttcgagc gtttggaact aaagtttcaa gcgtatgaaa
    16441 ctctagtttc tcaccgatga aactacagtt tcacaccgat gaaactctgg tttcaagcaa
    16501 tggaaactct ttgaagatac tgctaaattg gaattggtga tgtgtactgt gtacttccct
    16561 aataatggtt gacttgttta tctctaatag ctgctatgtg ttgactagaa atattactaa
    16621 ccctgg
//
