LOCUS       c00191_gnlPro..        16764 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MPJFCAJB_211.
ACCESSION   c00191_gnlPro..
VERSION     c00191_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:47:51
            Original ID  :: gnl|Prokka|MPJFCAJB_211
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16764
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16764
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9939:13497](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(9940..13497)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16764
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16764
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             281..1507
                     /locus_tag="ctg191_1"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
     CDS             1840..4593
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg191_2"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             4621..4953
                     /locus_tag="ctg191_3"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(4916..6202)
                     /locus_tag="ctg191_4"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPIPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             6675..7901
                     /locus_tag="ctg191_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7898..8728
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg191_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             8756..9616
                     /locus_tag="ctg191_7"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVIPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(9627..9815)
                     /locus_tag="ctg191_8"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(9940..13497)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg191_9"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(13531..14736)
                     /locus_tag="ctg191_10"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             14916..16070
                     /locus_tag="ctg191_11"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
ORIGIN
        1 gagagttgca gtctgattca gcctatagtc atttaagact agtgtcaaag ttagttcact
       61 gcaactctac ttttcaaata tacacttata ttttgttgtg atatttaata ctgcaaatgt
      121 aaatgtgtca aaagcaacta aactctcctc cttcctgaag gaggggaatt tagttgcttt
      181 tgacacatct tcttttctgt ttcttatttc agtaaatgtc ccccttccct gtgttttgat
      241 ttactactta atctgttaat tattagaatg ataataacag atgttctttt ttctaattgt
      301 ccccctcttt cttgccttgt tttataagcc gattgcctat ctttgcggca ggtttttaaa
      361 taataaatca aaaagagaaa actactttat gaaacacatt tcgaacttcc tcagatcaaa
      421 aagctggaac gtatttttgt ttttatatct tgctcttcct ttgtttgcgc aaaaggaata
      481 taagatcgat caggtatctg ttgttaatgt aggcgatggc agactgttgt ttcaggaact
      541 gaaaacggaa aaagcattga atggcgaaca tcgcatcata gatggttatc attccgccta
      601 tgtgctggca tcttttaaag atggttttta tgatggcgga tacaaagaat atgtggacaa
      661 tatattaata acggaaggaa gttataaaga agggcggaag gatggcctct tcaagattaa
      721 ctccaagttt gacggtaagc tgaaagaaga aaagtcctat aaggaaggta agctggacgg
      781 tacgagcaaa agttacttta ctaccggaaa agtggaaagt gaaagaaact tccggatggg
      841 gaaagagcac gggaagcaac tgtcgtacga atctgacggt actttgcgga aagagcataa
      901 ttacaaggac gggaagcagg taggcaaaca gtatactttt ctgaaaggta catatgattt
      961 gtatgagacc gtttatttca atgaagaagg ttttcaggac ggtgaatatt cgtccgtgtt
     1021 tacgtttggc tcgccacgta tactgggtag ttataagaat ggaaagaaga atggtcgttg
     1081 gactactttt gctgaaagcg gagatacgct gatgattgaa acctatctgg atggaaaaga
     1141 agatggactc catgtctcat ttgccaacgg aagtggggta aggcagaaag aatattatat
     1201 gaagaacgat cgtaaagacg gtttataccg tgaatataat ttggaaaatg gtgaattgag
     1261 atatgaagct acctatcagg ccggcagatt gcatggcaag gaacgacggc tgatagtgag
     1321 caaccgcttt gattattggg aaacttctac ctatgtgaac ggaaggcaga acggaccgtt
     1381 cgaagctcgt tatgtaaaga atgaccagct tcgtgaatgt ggggaatata agaatggtca
     1441 ccgtgtagga cgatggaaac gctacactat tgatggtaaa ctggaaaagg aatgggatga
     1501 aaactaaccg gtagatgaaa ggtcagagca taaaaaaagg agcaacgcct tgctccaacc
     1561 tttgttaacc ttaaatctaa tactatgaaa aacacagtgc aaagatacgg acttctgtga
     1621 aatctgcaaa ttatccaagt aaaacgctat gttttataac attgattaag tgtttgtttt
     1681 acgctttata cttttgttaa tactttccga tggtctgaaa gaggactgct ttccttcttt
     1741 ttagaataat aaatagctga agttagagaa ctttacagta ttatttctta tttttgttct
     1801 taattggatt acagaaagaa ctatgaaatg atgagatgga tgaagacgat gagatatctg
     1861 aagtggatgc tggtgctgtt tggtttaatc gggatgacgg cttgccggca ggatacaccc
     1921 cgttttcgta ttggggtggc tcaatgcagc gatgattcat ggcgacataa gatgaatgat
     1981 gagattcttc gggaagcgat gttttataat ggtgtttcgg tggaaatccg ttcggcaggg
     2041 gatgataaca gtaagcaggc ggaagatgtc cattatttta tggacgaagg agtcgatctg
     2101 ctgattattt ccgctaacga agctgctcct atgactccga ttgtagaaga agcttatcag
     2161 aaaggcatcc ccgttattct tgtagaccgg aagattcttt cggataaata tactgcctat
     2221 atcggagccg ataattatga aatcggtcgt tcggtaggaa actatattgc ctccagtctg
     2281 aaagggaagg gaaatatagt agaactgaca ggattgagcg gttcgactcc tgcaatggaa
     2341 cggcatcagg gatttatggc tgccatcagt aaattcccgg atataaagct gattgataaa
     2401 gcggatgctg cgtgggaacg tggtccggca gagatagaaa tggatagtat gcttcggagg
     2461 catcctaaga ttgatgctgt gtatgcccat aatgaccgta tcgctccggg tgcctatcag
     2521 gcagcaaaga tggcagggcg ggagaaggaa atgatttttg tcggcataga tgccttgccg
     2581 ggtaagggaa acggactgga actggtactg gacagtgtgc tggatgccac ctttatctat
     2641 ccgaccaatg gcgataaggt actgcaactg gctatggaca ttctggagaa gaaaccctat
     2701 cccaaagaaa cggtgatgaa taccgctgtt gtggaccgta ccaacgcaca cgtcatgcag
     2761 ttgcagacca cacacatttc cgaactcgac aaaaagattg aaacgctcaa cggacgtatc
     2821 ggtggctatc tctctcaggt agctacacaa caggtcgttt tatacggcag tctgattatc
     2881 cttttattgg tagccggctt attattggtc gtttataaat cactccgctc taagaatcgc
     2941 ttgaataaag agctttttaa gcagaagcag caattggaag agcagcgtga caaactggaa
     3001 gaacagcgtg accaattgat acagctctct catcaactgg aagaagctac ccatgccaag
     3061 ctggtctttt tcaccaatat ttctcacgac ttccgtactc cgttgacatt ggttgccgac
     3121 ccggtagaac atttgttggc ggacaagaca ctgagcggag atcagcaccg gatgctcatg
     3181 ctgattcagc ggaatgtgaa cattcttctg cgtctggtca atcagattct ggatttccgt
     3241 aaatatgaaa acggcaagat ggaatatact ccggttacgg tggatgtcct ttcttctttc
     3301 gaaggatgga atgagtcttt tcaggcggca gcccgtaaga agcatatcca tttttctttt
     3361 gatagtatgc cggatacgga ttatcataca ctggcagaca tggagaagct ggaacgtatt
     3421 tatttcaatc ttctgtccaa tgcctttaag tttacaccgg aaaacgggaa aatagccgtc
     3481 cgtctgtctt cccttagtaa agaggacaag cgatggatac gtttcacggt ggcaaatacc
     3541 ggttctatga tttctgccga acatattcgc aatgtattcg accgtttcta taagatcgat
     3601 atgcaccata ccggttcggg aatcggactg gcattggtaa aagccttcgt agaaatgcac
     3661 ggtggtatga tctccgtaga gagcgatgag aaacagggca cggtctttac cgttgaactg
     3721 cctgtacagt cttgtgaggc tgttgctgcc gaaccggata ccacccttgt ttctgcggat
     3781 tcccgtacaa cagatgttct attggcggaa gaggaagaac tggaaaaagg atatgactct
     3841 tccaaaccgt ccgtactgat tattgatgat aatgaggata tccgttcgta tgtccatacg
     3901 ttgttgcata cagactatac ggtgattgaa gcggcagacg gctccgaagg aatccgtaag
     3961 gctatgaagt atgttccgga cctgatcatt tctgatgtga tgatgccggg cattgatggc
     4021 attgaatgtt gccgccggct gaaaagtgag ttacagacct gtcatattcc ggttattctg
     4081 ctgacagcgt gttcactgga cgaacagcgt attcagggat atgacggtgg tgcggattct
     4141 tatatttcaa agccgttcag ttcacagctg ttgctggcac gtgtccgcaa tctgatcgat
     4201 tctcaccgtc gtctgaaaca gttctttggt gacgggcaga cattggcaaa agaagatgtc
     4261 tgcgatatgg acaaggattt tgtagaaaga ttcaagtcat tgattgaaga gaaaatggga
     4321 gactccggtt tgaatgtgga ggacttgggc aaagacatgg gactaagccg tgtgcagctt
     4381 tatcgcaaga ttaaatcatt gactaactac tctccgaatg aattgctccg tatcgcccgt
     4441 ttgaagaagg cagcttcttt gcttgcttct tcggacatga ccgtagcgga gattggttat
     4501 gaagtcggtt tcagttcacc ttcttatttc gccaagtgct ataaagagca gtttggagag
     4561 agcccgacag atttcctgaa aaggaaagga tgatttcatt gatatcgtaa agagggatat
     4621 atgaaagatt ataaagtaga taaagagagc ttttccgaat cctttcggaa ggaagtgtac
     4681 gaagtcgtat cccagatacc tgtgggaaaa gtatctactt atggaggtat tgctttgctg
     4741 ttgggggcac cccaatgctc gcggatggtg ggacgtgcat tgaaagaagt gccggatgaa
     4801 ttatccattc cctgccatag agttgtaaat tccaccggaa ggctggtgcc cggttgggtg
     4861 gaacaaaaac aactcttgct ggcagaagaa gtttctttca aagctaacgg atgcgttaat
     4921 ctgaaagaac atttgtggca cgtggatgaa tgaaggatgc aaggaaggta agccatatca
     4981 tccgtatcca tacaataaag aaaacccata catgaagcca taaggtcctg gtaatgaaat
     5041 ctctgatggg tatagggacg aatatgtcga taggaacgat acataacagc acaaaacagc
     5101 accaaaatag aatcttgtct gttgcggtac gtgttggtct gctccaatac cagagcatga
     5161 aacctgccaa tgcgataata taggtatgct tctcggcgga gtcactcagt aatactaccc
     5221 agcccatgag aatgcccaaa gcctgggcac ggaaggcaaa agacgaccat ttgcggaaat
     5281 tccccaaaaa gagcagagtc agcaagccga gcattcctat ctgaagtgca cggaagtgtg
     5341 gcaatgtcca tgctgcaatg gggcgggcat agaaaaatga atcataagct ccggcggact
     5401 gatgaacagc aagactatgg caccattctt cataataggg gagcaaatct gcaggagcta
     5461 ttttgattaa cggtaatgca agcaatacaa tgcccattgt aacggcatag ccaaagttac
     5521 gccatacgtg aggatagcac agcaacaatg ccagttcgaa aattccatat actttggtac
     5581 atcccgaaat catgattaac agaacagcca gaaatccacg gtctttttcc aataacgtat
     5641 aggcgaataa gaataaatag gctaccgtta tgttatactg aaatgaaagt aaactttgtc
     5701 ctaaaatcag taacagaaaa aggaacatac ggcatttctg ctgctgggtg aattgttggg
     5761 gcagcgtgaa gatcgccata aagaacagcg aataattgaa tagattccac gcgaaaggtc
     5821 ccagccatgc aggcagatac gcaaacggag cgaacaatac cgtgaaaact ggagaataaa
     5881 ggaagtagcg tccgtgagct tctacaaatt cagttgtgta tgggctgatg ccttgccaga
     5941 agaattgagt agcgtccgag aagaccataa agttttgatg ccgtcctcgt ataaattcga
     6001 gcagagtcac tataaaagcg agcaggaaac ctatcatgta gagattccgc cggctataga
     6061 aaaacggcat tttggggttc tttttactaa ggaactgtac ttggcttttg tcgtctagtg
     6121 tggcagtacc tgtttgtttt tcttttgttg tgtaatgaca attatccttc cccaggaaaa
     6181 ttgtaatagc cctgttgaac atataaatct agtttagtta ttgacgccaa atatacggtg
     6241 tttaagtgaa atattcaaac ttattttata tttatctgcc ggtttgttct attttgctga
     6301 gtgatagggg aatattaccc ggaaactttc catatcatta caaataaagc cctctgtatg
     6361 ccccggattt tgaatataat ttgtatgttt aatccgtttt ttgtatcttt gtgccagcaa
     6421 gatactggaa caggctgttt ttatacataa aaatgctatt ttttgctatt cgttgaaagg
     6481 attatcttat caaattctat tcctttttta attactcagt ctgtcaataa tcattttatt
     6541 aattatttcg ggattcattg ttatttgtcc cttatttaaa tcagaacttt atacgatata
     6601 aagaaagatt cctgttatcg tttgttcttg tcttgctgtg tatattattt taataaccta
     6661 aaccatttta ttgtatgagt aaaatagaaa ttaaagatct ctatctggtt tttggcaatg
     6721 agaagcagaa ggctttgaag atgttgaaag aaggtaaaac aaaaagtgaa atattgaaag
     6781 cgaccggatg tacagttgcg gtgaaagatg cgaatctttc cattaatgaa ggcgaaatat
     6841 tcgtcattat ggggctgtcc ggtagtggaa agtccacttt actccgctgc atcaaccgtt
     6901 tgatacgccc tacttccgga gaagtgatta tcaatggaac agacatagcc aaagtgtcgg
     6961 ataaggaact gttgcagatt cgccggaaag aactggctat ggtctttcag aacttcggtc
     7021 tgcttcctca ccgttctgtc ttgcataata tagctttcgg gctcgaacta cagggagtaa
     7081 aaaagggaga acgggagcag aaagcgatgg aaagtatgca actggtgggg ctgaaaggct
     7141 acgagaatca gatggtaagt gaactgtcgg gtgggatgca gcagcgtgtc gggctggcgc
     7201 gggctttggc caataatccc gaagtcctgt tgatggatga ggccttctcg gcactcgatc
     7261 ctttgatccg tgtgcagatg caggatgaac tgctgacttt gcagtcgaag atgaaaaaaa
     7321 cgattgtctt tattactcac gacctgagtg aagcgattaa attgggtgac cggattgcta
     7381 tcatgaagga tggagaaatt gtacaaatcg gtacatcgga agaaatcctg accgaacctg
     7441 ccaacgctta tgtagaacga tttgtggaga atgtagatcg aagcaagatt ataacagctt
     7501 cctctgttat ggtagataaa cccatagtgg cacgtttgaa gaaagaaggc ccggaggtgc
     7561 tgatccgtaa gatgcgcgaa cggaatctga ccgttcttcc ggtagtcgat tccaataatc
     7621 tgttagtagg agaggtgcgg ttgaatgact tgctgaaact acgaaaagag caaatccgct
     7681 ccatcgagtc cgtagtaagg catgaagttc attcagtgct gggtgatacg gtgctggaag
     7741 atattcttcc gttgatgaca aaaacgaact cgccaatctg ggtcgtaaat gagaatcggg
     7801 agtttgaagg cgtagtgcca ctttcctcat tgatcatcga agtaacggga aaagataaag
     7861 aagaaattaa tgaaatcatt caaaacgcaa tagaattatg ataaatatcg gacaatatat
     7921 agagactgcc attaattggc tcacagaaca ttttgcttcc ttttttgatg ctctcagcat
     7981 ggggatcgga ggattcatag acggttttca gcacgtactg tttggaatac ctttttatat
     8041 cacaattgca gtgctggctg cgctcgcctg gtttaagtcg ggtaagggga cagccgtatt
     8101 taccctcttg ggtttattgc ttatttacgg catgggcttt tgggaagaaa cgatgcagac
     8161 attggcattg gtactttctt ccacttgtct ggcattgctt ttaggcgttc cgttgggaat
     8221 ctggactgcc aacagtgatc gttgtaacaa gataatgcgc cctgtcctcg actttatgca
     8281 gacaatgcct gcctttgtct atctgattcc tgccgttcta ttcttcggat tgggaactgt
     8341 gccgggagct tttgccacca tcatctttgc aatgcctcct gtggttcgtc tgactggtct
     8401 gggcattcgt caggttccta aaaatgtagt agaagcctcc cgttcttttg gagctactcc
     8461 ctggcagctt ctttataagg tgcaattgcc tttggcattg cctactattc tgacgggaat
     8521 caatcagacg atcatgatgt cactttcgat ggtagtgatt gccgccatga tttctgcggg
     8581 agggttggga gaaatcgtgc tgaaaggtat cacccaaatg aaaatcggac tcggatttga
     8641 aggcggtatc gcagtcgtga tattggcgat cgtgctggac cgcatcactc agggtatggc
     8701 agataacaga aaaagtaaaa agaaataaga atcacaccaa agaaaggaat aatcaatgaa
     8761 taagataaaa atgattgcgg caatgtttat tgccggcata ctcttaacct tcgtttcctg
     8821 cggagacaac ggaaagagta agaagataag tatcgcttat gccaactggt cggaaggtat
     8881 tgcaatgaca aaccttgcca aagcgatttt tgaagatcag gggtacgatg taaagttgct
     8941 gaatgccgac cttgcaccta tatttacctc tatctcccgt aagaaagcag acgtatttat
     9001 ggatgtctgg atgcctgtca ctatggaaga ttatatgaaa caatacgggg ataaactcga
     9061 agttatcggg gatatttatg atggtgcccg tatcgggctg gtgattccgg attacgttac
     9121 gatcaactca atcgaagaac tgaacgcgga aaaggaacgt ttctccggtc agattgtcgg
     9181 tattgatgcc ggagccggta ttatgaaagc taccgatcag gccatcaaag actatggatt
     9241 ggattataaa ctgatgactt cgagcggacc tgccatgact gcttccctaa agaaagcgat
     9301 tgataagaaa gactggattg tcgtgacggg atggacgcct cactggatgt tcgaccgttt
     9361 caagctgaaa gttcttcagg acccgaagct gatatatgga aatacggaat ccattcatac
     9421 catagcatgg aaaggtttta gcgagaaaga cccttttgct gccgaacttt tgggcaacat
     9481 tcgtctgaca gatgcggaaa tcagctcttt aatgactgct ctggaagagg cgcagacaac
     9541 ggaaagacag gctgcccgtc aatggatgga agaacatcag gaactggtaa acagttggat
     9601 tcctgagaaa gattgatatg caaacactac ttcaaccatc ctgccattct ttctttacca
     9661 tagaagtagt agaaaagtag tcccagccag ctggtaagaa cgattaatac aatcgctata
     9721 agtcttttct ctacagccgc atttatattc caaatctcta tggcagctct gaaagtcagt
     9781 atcaaaccga taatccaaat aacaaatccg atcatatctt tagagtttta atgaatatct
     9841 tcgtgagaag taatcgttac ttctaagata taaacaaaaa aggcaggaat ctgtttccag
     9901 gattcctgcc ttttattatg tataaagtat ttctacttat tattcagctg tatcagctcc
     9961 ccagttttct ctggcaagac gtttgtagct gttgtaacgc catttagcgt tttcttcagc
    10021 agctttaaac agttcttcag cttcagcagg atattgtttc attacagaag cgtaacgaac
    10081 ttcacccttc aagaaacctt ggaagtcttc ccagttaggt tctttgctat ccagttggaa
    10141 cggattcttg ccttcttctt ccaaagcagg gttgtaacgc cacaagtgcc agtaaccgca
    10201 cttaacagcc ttttcttctt cttcctggct cttacccata ccggctttca gaccgtggtt
    10261 gatacatgga gcgtaagcga tgatcagtga tggtcccgga tatgcttcag cttcacggat
    10321 agctttcaga gtctgagcct ggtcagcacc catagcaatc tgagcaacat atacataacc
    10381 gtaagtagta gccatcagac cgaggtcttt cttacgtaca cgcttacctg cagcagcaaa
    10441 cttagcgata gcgcctaccg gagtagcttt agaagactga ccacctgtgt tagagtaaac
    10501 ctcagtatcc aatacaagga tgttaacgtc cttaccggaa gcgattacat ggtcaagacc
    10561 accgtaaccg atatcataag aagcaccgtc accaccgatg atccattggc tgcgtttaac
    10621 aagatattgt tgcagatcag cgatttgctt gcagtggttg catttatctt tagcagcttc
    10681 taccatcgga atgatctttt cggccagttc cttagtcttt tctgcatcca gcatattgtt
    10741 gatccattca gcaaatactt ctttgtattc agccgggcag caatcagaag cgatagcttc
    10801 gttcattact ttcaccagac gggcacgcat cttttcgtta gccagttcca tacccagacc
    10861 aaattcacag aagtcttcga acaaggagtt agcccatgca ggaccgtgac ccttttcgtt
    10921 catagtgtac ggagtagaag gaactgaacc ggagtagata gaagaacatc ctgtagcgtt
    10981 agcaaccatt tcacggtcac cgaacaactg agaaatcagt ttcacgtacg gagtttcacc
    11041 acaaccggag caagcgcctg agaactcaaa caacggagtt gcgaactgag agttcttcac
    11101 gttagccttg atgtctacca ggtgttgttt gctcttcacg ttttcagcgc agtaagtcca
    11161 gttatcagct tcggccaact ggctttcaag gtgtttcatg gtcaatgcct tgccaccctt
    11221 cttcggatta cccggacaga tgtcggcaca gttaccgcaa cccagacagt cgagaacgtc
    11281 tacctgaata cggaatgtca taccatcgaa tgctttacct acagctttca gttgctcgaa
    11341 cttagcaccc ttctgctctt cagcatcgag tacgaacgga cggatagaag cgtgaggaca
    11401 aacgtaagca cacttgttac actgaataca gttttcagca ttccattcgg gaacgaatgc
    11461 agctacacca cgtttttcgt atttggaagt accttgatac caagtaccgt cttcgatacc
    11521 cttgaatgca gataccggca gcaagtcacc gtcctgtgca ttgatcggac gaactacttc
    11581 gttgatgaaa gcaggatcat tgttttctgc ttttgcatca tccggcaggt tagcccaagc
    11641 aggatcgaca gtcagagtct tgtattcacc accgcggtct acagcagcgt agttcttgtt
    11701 aacaacgtct tcacccttct tgccgtaaga cttaacgatg aatttcttca tctgttcaac
    11761 agcttgatct acagggatta cgcctgtgat acggaagaat gcagactgaa ggattgtatt
    11821 ggtacggttg cccaaaccaa tttccattgc aatctgagtt gcgttgatat agtatacaga
    11881 gatgttgttc tgtgcaaagt atttcttcac cttgttaggc aggttcttag ccagttcttc
    11941 gccttcccag atggtattca gcaagaaaga accgttctta cgcaaaccac gtgttacgtc
    12001 gtacatgtgc aggtaagcct gaacgtgaca agcaacgaag ttcggagtat ttaccaagta
    12061 agtagaacgg atcggagtat caccgaaacg caagtgagaa caagtgaaac cacccgactt
    12121 cttggagtcg taagagaagt aagcctgaca gtgtttgtcg gtgttgtcac cgataatctt
    12181 aacagagttc ttgttggcac ctactgtgcc gtcagcaccc agaccgtaga atttagcttc
    12241 gaacatacct tcaccgccca gagcgatttc ttctttctga ggaagagaag tgaacgtaac
    12301 gtcgtctacg ataccgatag tgaagtggtt cttcggcatt ggcatagcca agttttcgaa
    12361 tacagagatg atctgtgccg gagtggtatc ttttgaaccc agaccgtagc gaccgccaac
    12421 gataacagga gcattttctg cgccatagaa gcagtcttta acgtcaaggt aaagaggttc
    12481 gccgttagca cccggttctt ttgtacggtc aagcactgcg atgctctttg cagtcttggg
    12541 tacagcagcc aggaagtgtt tagcagagaa cggacgatac aagtgtacgg caaccatacc
    12601 tactttttcg ccgtttgcta ccaagtggtc gatagcttcg cgggcagctt cagttacaga
    12661 acccattgcg ataattacgc gttctgcatc ttctgcaccg tagtaatcga acaaaccgta
    12721 tttgcggcct gtgatcttgg aaatttcgtt catgtattct tctacgatag caggaactgc
    12781 ttcatagtag ttattgcatg attcacgatg ttggaagaag tggtcggggt tttcagccat
    12841 accacgggca accggcttca tcggattcag tgcacgggca cggaattcag ccaaagcttc
    12901 ctggtcgatc agcggagcga ggtcgtcgtt ttccaacatt tcgatcttct ggatttcgtg
    12961 agaagtacgg aaaccatcga agaagttcat gaacggaacg cgtgatttga tagtagccag
    13021 atgagcaaca cctgccaaat ccataacttc ctgtacagaa ccttctgcca acatagcgaa
    13081 gccggtttga cgagctgaca ttacgtcctg atggtcaccg aagatacaca atgcgtgaga
    13141 agccagtgta cgagcagaaa cgtggaatac acaaggcaag aattcaccgg caatcttgta
    13201 catgttaggg atcatcaaaa gaagaccctg agaagcagtg taagtagtag tcaatgcacc
    13261 agcctgaaga gaaccgtgaa ctgcaccggc agcaccacct tcagattgca tttcctgtac
    13321 caatactgtt tcgccgaaga tgttcttacg tcctgcggca gcccattcgt ctacgtactc
    13381 agccatagtc gaagaaggag tgatggggta gatagctgct acttcagaga acatatacga
    13441 gatatgtgct gcagcttggt taccatcaca tgtgatgaat ttcttctgtt tagtcataac
    13501 taaattaaat atttaagtaa ataaatcttt ttagtataag aatccgaaca tccaaagagg
    13561 tatttggttg ccgcggccta tctcggcctt ttgcaacgca tacgtcacgt ccgggttatt
    13621 ctttattttt gtaccttccg cacaaatttt gaacggcatc acttcgtcta ccatgaaaga
    13681 gacgttttta tctcctttat gtaccttatg gtctttccat aaagtgttaa cgaagaacgt
    13741 gtcgagtaca tcctgttctt ccactttcac cggataaatg gagtacatca ggttagagtt
    13801 gtgcatcata atctttgacg gtttctttgg gaattcttct cctttcgggt aaaccagatt
    13861 aatcagacgc gcgtctgcca gatacttgat atagttcatt accgtagcgc gggatgtctg
    13921 tacgtcactt gccagttggc tcacgttcgg agctttcggt ccgtccacag ccaacaaata
    13981 tagtaatttt tttatctttg aaagatattt cagctcaatt tgtttgatca gcaagatatc
    14041 cacttctacc atcatgttca ttgttttcag cagattctcc gagaaattac gtttttcaag
    14101 gaagaaaggg tagaaaccat gatgcaggta atcctgaaaa taatccagcg gtcgtacttt
    14161 ggaaagtact cctttggcta tctgttcatg tgtactgagg atttcttcga ggctgtatgc
    14221 ccggaatttc attcctgtct gcaggttcag aaattcacgg aaagagaatc cgcgcaggtt
    14281 ataacttttc gcaatgtcac gcaattcgag gttttcctct ttgagtcgca tgacggaaga
    14341 accggtgaag acaatcttca ggctggggaa acggtcatag cacattcgta gctctttgct
    14401 ccattcggga tgtttgaaca cctggtcgat cagcagtact tttccgccac gtttctgaaa
    14461 ctcgttggcg aagtcaacaa ggctgtgacc ggagaaataa aagttgttca tattgatgaa
    14521 cagacaggaa cggtcggtgc cgaatttctc tttggcgtac tgcaggagga aagtggtttt
    14581 tcctacgcca cgtgtccctt tgataccaat cagacggtca ctccagtcga tctcgtccat
    14641 aagatcgcgg cgaacggggg cattggtgtg ctcaacgagg taggcgtgtg tgcgatagaa
    14701 tgattccatt tcgtttcttt gtttttcggc tggcaaatat agtgcttttt ttaggatttg
    14761 caaagtagag atagcaaaaa tgtgctttaa tttataagtt tctctttatt gtgtaagttc
    14821 ctgattattt cctgtatata tttgcagaat aatgtgttga atccatcttt gacatgacga
    14881 aaagacctgt ttatatattc aatccggagc atgatatggc gttggcaagc ggtgagacga
    14941 actatatggc gccggcttcc gcccgacaga tggcgagtga cctggcgttg cttcctatgt
    15001 ggtatgccga agcgggaagt gcggtgcttg caccgtctgc ttataatgcg gacttcctga
    15061 aaacaaagag tgaacttttg ggcatggatg tggccttgtt gacggaaccg gaagtggctg
    15121 acggtaaaga ctggaagttc tctccgtggg gttgggaccc tgctttgcgg aagcgtttga
    15181 tgacattggg ggcaggtcag acggagctgc cttctgcgga ttatatgaat attctgagag
    15241 agcattcgca tcgtctgcag gcggtaaagt tgttgcctgg gttgcggttg aatgaatact
    15301 tctgtggaga atctttttat ttgagtactt tggcggagtg cagtgcgttc gtcgaagggc
    15361 gggaagcgtg cttgttaaaa gctccgcttt ccggaagcgg gaaaggattg aattggtgta
    15421 aaggcatatt tactactttt atttccggtt ggtgtgcccg tgtcgctgct tctcagggtg
    15481 gggtggtagg cgaacctata tataataagg tggaagattt cgctatggag ttttatgctg
    15541 acgggagagg aagggttgtt tttgccggat attcggtctt ccacacgggt gggagtggga
    15601 tgtatgcagg gaatgacttg ctgtctgacg agaagattct gcagaaacta tcggcttatg
    15661 tgccacaaga agaatttatc aggctgcgga ctcgtttgga agaagaattg tcagctttgt
    15721 tcggtggctt ttatcatgga tacttgggag tggatatgat gatttgtcat tttccggatg
    15781 aagcgcctgt ttaccggatt catccttgtg tcgaaattaa tctgcgaatg aatatggggg
    15841 tggtggcatg gctcttgacg gatcgttatt tggctgcgga tgcggaagga gtttttcgga
    15901 ttgattatta tcctttagcc ggtcaggctt tggaggaaca tcggcagatg tcggcttcgt
    15961 tccctttgtc cgtagagaat aatcgggtgt gtgccggata tttgccgtta gtaccggtga
    16021 cgcctcaaag ccggtatcgt gcgtttcttt tgcttactct cccccagtga aaaagatagt
    16081 gcttttgctc tcatgctcta acagttcgtc tgtatccctt tattcatcga tgttttagct
    16141 gttagagatc cagtggtagc agagtgagag caaggacttg ctctcactct gcatcgtcct
    16201 gataaatact gtttttactg tgttattctt tgatttacag gatgttaata tctgatatct
    16261 caactgttaa cgtttgattt ctcagatatt aataattgag aaatcaagta ttaaggactg
    16321 ataatttatg tattattgac tgatatatga tttaatgttt tcagagagag cagtactatt
    16381 gaagtagctg atgcgttcaa tgtgattgga acatgcggtt aagtcaatca aatcaacagt
    16441 agtttcagat agtttcgagc gtttggaact aaagtttcaa gcgtatgaaa ctctagtttc
    16501 tcaccgatga aactacagtt tcacaccgat gaaactctgg tttcaagcaa tggaatgatg
    16561 tgtactggtt ttagttgaca acttcgtttg ttataactga attagtttac tcaatatact
    16621 ttaatatcta aataggttta cttttgttat tcttattcct atgttagttg tcttttgttg
    16681 gtgcttgcaa atttatgcat cttcctttat ttacgcaagc cttcntcagg aaaatgtaat
    16741 gttgccaaca accaaaaact cttc
//
