GCA_017156775.1 - 6 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaHPDNJDKM_5 (original name was: gnl|Prokka|HPDNJDKM_5)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	lanthipeptide-class-iv	36,516	50,042

gnlProkkaHPDNJDKM_7 (original name was: gnl|Prokka|HPDNJDKM_7)

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	lanthipeptide-class-iv	26,797	44,319

gnlProkkaHPDNJDKM_8 (original name was: gnl|Prokka|HPDNJDKM_8)

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	lanthipeptide-class-i	5,660	28,093

gnlProkkaHPDNJDKM_14 (original name was: gnl|Prokka|HPDNJDKM_14)

Region	Type	From	To	Most similar known cluster		Similarity
Region 14.1	NRPS	1	32,992	macedocin	RiPP:Lanthipeptide	28%

gnlProkkaHPDNJDKM_16 (original name was: gnl|Prokka|HPDNJDKM_16)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	RaS-RiPP	1	17,969

gnlProkkaHPDNJDKM_20 (original name was: gnl|Prokka|HPDNJDKM_20)

Region	Type	From	To	Most similar known cluster		Similarity
Region 20.1	NRPS-like	1	19,357	asukamycin	Polyketide:Type II polyketide	4%

Region	Type	From	To	Most similar known cluster	Similarity
Region 5.1	lanthipeptide-class-iv	36,516	50,042
Region 7.1	lanthipeptide-class-iv	26,797	44,319
Region 8.1	lanthipeptide-class-i	5,660	28,093
Region 14.1	NRPS	1	32,992	macedocin	RiPP:Lanthipeptide	28%
Region 16.1	RaS-RiPP	1	17,969
Region 20.1	NRPS-like	1	19,357	asukamycin	Polyketide:Type II polyketide	4%

Compact view

gnlProkkaHPDNJDKM_5 - Region 1 - lanthipeptide-class-iv

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Location: 36,516 - 50,042 nt. (total: 13,527 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-iv: (cds(LANC_like and Pkinase) and not micKC)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.

gnlProkkaHPDNJDKM_7 - Region 1 - lanthipeptide-class-iv

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Location: 26,797 - 44,319 nt. (total: 17,523 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-iv: (cds(LANC_like and Pkinase) and not micKC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.

gnlProkkaHPDNJDKM_8 - Region 1 - lanthipeptide-class-i

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Location: 5,660 - 28,093 nt. (total: 22,434 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.

gnlProkkaHPDNJDKM_14 - Region 1 - NRPS

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Location: 1 - 32,992 nt. (total: 32,992 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 32992:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Leu) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg14_15

Search NORINE for peptide: strict or relaxed

AMP-binding (13..412): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DFWSLGAVCK
Nearest Stachelhaus code(s):: Leu DAWLLGAVCK (62% 8Å match)
Stachelhaus code match:: 80% (moderate)

ctg14_16

AMP-binding (248..639): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DNWSYGEITK
Nearest Stachelhaus code(s):: Ile DFWSTGVILK (50% 8Å match)
Stachelhaus code match:: 60% (weak)

gnlProkkaHPDNJDKM_16 - Region 1 - RaS-RiPP

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Location: 1 - 17,969 nt. (total: 17,969 nt) Show pHMM detection rules used

Region on contig edge.

RaS-RiPP: (PF04055 and TIGR01716)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaHPDNJDKM_20 - Region 1 - NRPS-like

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Location: 1 - 19,357 nt. (total: 19,357 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

NRPS/PKS substrates

NRPS/PKS substrate predictions

ctg20_4

Search NORINE for peptide: strict or relaxed

AMP-binding (6..388): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVTSCALIYK
Nearest Stachelhaus code(s):: Ala DVTNFALIYK (62% 8Å match)
Stachelhaus code match:: 80% (moderate)