## Fri May  2 13:59:02 2025
## emapper-2.1.12
## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_017299595.1/GCA_017299595.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_017299595.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_017299595.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
AKELHBIC_00001	78345.BMERY_1183	2.65e-50	174.0	COG0433@1|root,COG0433@2|Bacteria,2INIE@201174|Actinobacteria,4D1JH@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
AKELHBIC_00002	78345.BMERY_1183	7.33e-39	143.0	COG0433@1|root,COG0433@2|Bacteria,2INIE@201174|Actinobacteria,4D1JH@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
AKELHBIC_00003	1437608.BBIA_1062	1.09e-21	91.7	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZUB@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	tnp3521a2	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
AKELHBIC_00004	1437608.BBIA_1062	4.05e-14	70.9	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZUB@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	tnp3521a2	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
AKELHBIC_00005	216816.GS08_09870	6.78e-30	114.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria,4D2KU@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
AKELHBIC_00006	216816.GS08_02225	1.13e-128	376.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria,4D2KU@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
AKELHBIC_00007	216816.GS08_02220	6.27e-176	493.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria,4D2Q1@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
AKELHBIC_00008	465515.Mlut_06470	3.34e-218	614.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,1W7QH@1268|Micrococcaceae	201174|Actinobacteria	L	PFAM Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
AKELHBIC_00009	216816.GS08_03825	1.25e-169	477.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria,4D2Q1@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
AKELHBIC_00010	216816.GS08_02215	1.14e-271	744.0	COG0582@1|root,COG0582@2|Bacteria,2HB7R@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
AKELHBIC_00011	78344.BIGA_0003	0.0	994.0	COG1484@1|root,COG4584@1|root,COG1484@2|Bacteria,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,IstB_IS21,rve
AKELHBIC_00012	445975.COLSTE_02474	5.24e-80	251.0	COG3631@1|root,COG3631@2|Bacteria,2IHRJ@201174|Actinobacteria,4CW51@84998|Coriobacteriia	84998|Coriobacteriia	S	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
AKELHBIC_00013	700015.Corgl_1392	2.73e-160	459.0	COG3049@1|root,COG3049@2|Bacteria,2GK9Z@201174|Actinobacteria,4CUI0@84998|Coriobacteriia	84998|Coriobacteriia	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
AKELHBIC_00014	216816.GS08_00995	8.53e-230	634.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZTH@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00015	700015.Corgl_1393	6.29e-164	466.0	COG3238@1|root,COG3238@2|Bacteria,2IB1U@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
AKELHBIC_00016	908339.HMPREF9265_1427	7.44e-104	308.0	COG5426@1|root,COG5426@2|Bacteria,1TNZD@1239|Firmicutes,4HTH8@91061|Bacilli	91061|Bacilli	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
AKELHBIC_00017	1445613.JALM01000003_gene4997	6.57e-89	276.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4DZYD@85010|Pseudonocardiales	201174|Actinobacteria	K	Periplasmic binding protein-like domain	-	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00018	398513.BBNG_01833	7.35e-12	63.5	COG2801@1|root,COG2801@2|Bacteria,2H9F1@201174|Actinobacteria,4D2FY@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_2
AKELHBIC_00019	762211.BSTEL_0440	7.01e-52	176.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D0ME@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_00020	326426.Bbr_1115	8.64e-179	498.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales	201174|Actinobacteria	L	IstB-like ATP binding protein	istB	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
AKELHBIC_00021	326426.Bbr_1114	0.0	956.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_00022	1437608.BBIA_0904	7.74e-183	517.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D0ME@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_00023	78346.BRUM_0084	1.67e-29	115.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZQK@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
AKELHBIC_00024	610130.Closa_3686	1.1e-123	360.0	COG1746@1|root,COG1746@2|Bacteria,1TT0X@1239|Firmicutes,24F68@186801|Clostridia	186801|Clostridia	J	tRNA cytidylyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
AKELHBIC_00025	610130.Closa_3687	3.18e-14	74.3	29T71@1|root,30EDT@2|Bacteria,1V71N@1239|Firmicutes,24KXJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00026	449673.BACSTE_00221	6.72e-46	157.0	COG1746@1|root,COG1746@2|Bacteria,4NPCC@976|Bacteroidetes,2FWHD@200643|Bacteroidia	976|Bacteroidetes	J	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
AKELHBIC_00027	702459.BBPR_0778	9.86e-184	519.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_00028	326426.Bbr_1533	1.15e-133	385.0	COG1040@1|root,COG1040@2|Bacteria,2HZQY@201174|Actinobacteria,4D1AY@85004|Bifidobacteriales	201174|Actinobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00029	326426.Bbr_1532	2.33e-193	541.0	COG0758@1|root,COG0758@2|Bacteria,2IFTH@201174|Actinobacteria,4D0JN@85004|Bifidobacteriales	201174|Actinobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
AKELHBIC_00030	398513.BBNG_01485	2.73e-100	301.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_00031	1693.BMIN_0225	2.15e-92	276.0	COG2826@1|root,COG2826@2|Bacteria,2GSCE@201174|Actinobacteria,4D1V0@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_38
AKELHBIC_00032	566552.BIFCAT_01245	2.51e-217	608.0	COG3274@1|root,COG3274@2|Bacteria,2GITX@201174|Actinobacteria,4D0JX@85004|Bifidobacteriales	201174|Actinobacteria	S	enterobacterial common antigen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
AKELHBIC_00034	326426.Bbr_0467	5.16e-115	329.0	COG1396@1|root,COG1396@2|Bacteria,2H7PX@201174|Actinobacteria,4D2H1@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
AKELHBIC_00036	547043.BIFPSEUDO_03286	2.72e-22	96.3	2D8CX@1|root,32TR0@2|Bacteria,2GPZP@201174|Actinobacteria,4D1AM@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacteriophage abortive infection AbiH	-	-	-	-	-	-	-	-	-	-	-	-	AbiH
AKELHBIC_00038	326426.Bbr_0464	0.0	1821.0	COG1413@1|root,COG1413@2|Bacteria,2GPDJ@201174|Actinobacteria	201174|Actinobacteria	C	Domain of unknown function (DUF4365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4365
AKELHBIC_00039	1437610.BREU_1897	1.59e-51	176.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_2
AKELHBIC_00040	702459.BBPR_0057	1.13e-59	200.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4D0D7@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_00041	702459.BBPR_0057	6.76e-122	362.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4D0D7@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_00042	326426.Bbr_1114	0.0	956.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_00043	326426.Bbr_1115	8.64e-179	498.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales	201174|Actinobacteria	L	IstB-like ATP binding protein	istB	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
AKELHBIC_00044	216816.GS08_09735	1.05e-99	294.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales	201174|Actinobacteria	L	IstB-like ATP binding protein	istB	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
AKELHBIC_00045	78346.BRUM_1693	6.8e-262	722.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4D0H8@85004|Bifidobacteriales	201174|Actinobacteria	K	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HTH_3,HTH_31,Transposase_20
AKELHBIC_00047	77635.BISU_1988	1.43e-304	838.0	COG2244@1|root,COG2244@2|Bacteria,2I92W@201174|Actinobacteria,4D06Y@85004|Bifidobacteriales	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00048	401473.BDP_1836	3.84e-58	197.0	COG1216@1|root,COG1216@2|Bacteria,2I2EQ@201174|Actinobacteria,4D2VS@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
AKELHBIC_00049	518635.BIFANG_03649	1.77e-70	230.0	COG1215@1|root,COG1215@2|Bacteria,2IPTK@201174|Actinobacteria,4D12W@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K19427	-	-	-	-	ko00000,ko01000	-	GT2	-	Glycos_transf_2
AKELHBIC_00050	35760.BCHO_0649	8.92e-67	222.0	2A6YJ@1|root,30VTI@2|Bacteria,2GSH6@201174|Actinobacteria,4D1KT@85004|Bifidobacteriales	201174|Actinobacteria	S	EpsG family	-	-	-	-	-	-	-	-	-	-	-	-	EpsG
AKELHBIC_00051	35760.BCHO_0646	1.57e-91	281.0	2CEUT@1|root,2Z86D@2|Bacteria,2IN4M@201174|Actinobacteria,4D0U1@85004|Bifidobacteriales	201174|Actinobacteria	H	Core-2/I-Branching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Branch
AKELHBIC_00052	35760.BCHO_0656	6.03e-23	98.6	COG1045@1|root,COG1045@2|Bacteria,2GNWQ@201174|Actinobacteria,4D1GR@85004|Bifidobacteriales	201174|Actinobacteria	E	serine acetyltransferase	cysE_1	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2
AKELHBIC_00053	1147128.BAST_1661	8.32e-112	330.0	COG1442@1|root,COG1442@2|Bacteria,2HFT7@201174|Actinobacteria,4CZBS@85004|Bifidobacteriales	201174|Actinobacteria	M	Domain of unknown function (DUF4422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4422
AKELHBIC_00055	518635.BIFANG_03644	2.63e-193	541.0	COG1216@1|root,COG1216@2|Bacteria,2I2EQ@201174|Actinobacteria,4CZNW@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyl transferase family 2	-	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
AKELHBIC_00058	326426.Bbr_0431	1.25e-140	397.0	COG0394@1|root,COG0394@2|Bacteria,2GMPR@201174|Actinobacteria,4D0GD@85004|Bifidobacteriales	201174|Actinobacteria	T	Low molecular weight phosphatase family	etp	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
AKELHBIC_00059	326426.Bbr_0430	3.49e-293	813.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CZ4J@85004|Bifidobacteriales	201174|Actinobacteria	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	rfbP	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
AKELHBIC_00061	1437610.BREU_0807	9.68e-77	231.0	28PY9@1|root,2ZCI0@2|Bacteria,2INBV@201174|Actinobacteria,4D13Q@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00062	1437608.BBIA_1622	3.74e-300	825.0	COG2865@1|root,COG2865@2|Bacteria,2IC6C@201174|Actinobacteria,4D0AE@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
AKELHBIC_00063	1437609.BCAL_0001	3.35e-24	98.2	COG3464@1|root,COG3464@2|Bacteria,2I00A@201174|Actinobacteria,4D2GS@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
AKELHBIC_00064	762211.BSTEL_0666	2.58e-199	562.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4D1CX@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
AKELHBIC_00065	398513.BBNG_00086	6.66e-34	130.0	COG1409@1|root,COG1409@2|Bacteria,2GNU9@201174|Actinobacteria,4CZXA@85004|Bifidobacteriales	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos
AKELHBIC_00066	702459.BBPR_0164	0.0	1383.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ38@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location Cytoplasmic, score 8.87	bga1	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
AKELHBIC_00067	216816.GS08_07745	0.0	937.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CZ12@85004|Bifidobacteriales	201174|Actinobacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
AKELHBIC_00068	216816.GS08_07750	5.61e-24	92.0	2B5FT@1|root,31YAF@2|Bacteria,2GV5R@201174|Actinobacteria	201174|Actinobacteria	S	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	-	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
AKELHBIC_00069	216816.GS08_07755	5.56e-215	593.0	COG0483@1|root,COG0483@2|Bacteria,2HGP2@201174|Actinobacteria,4CYWZ@85004|Bifidobacteriales	201174|Actinobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
AKELHBIC_00070	216816.GS08_07760	0.0	1076.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4CZAN@85004|Bifidobacteriales	201174|Actinobacteria	S	Pup-ligase protein	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
AKELHBIC_00071	216816.GS08_07765	0.0	984.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4CZ86@85004|Bifidobacteriales	201174|Actinobacteria	O	AAA ATPase forming ring-shaped complexes	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
AKELHBIC_00072	216816.GS08_07770	6.09e-161	451.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,4CZZA@85004|Bifidobacteriales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
AKELHBIC_00073	216816.GS08_07775	7.09e-164	459.0	COG0560@1|root,COG0560@2|Bacteria,2GJDH@201174|Actinobacteria,4CYWC@85004|Bifidobacteriales	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
AKELHBIC_00074	216816.GS08_07780	0.0	1507.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4D04J@85004|Bifidobacteriales	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
AKELHBIC_00075	216816.GS08_07785	1.24e-170	476.0	COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,4CZGV@85004|Bifidobacteriales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
AKELHBIC_00076	216816.GS08_07790	2.3e-229	632.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CZ8C@85004|Bifidobacteriales	201174|Actinobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
AKELHBIC_00077	216816.GS08_07795	0.0	1178.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CZ1T@85004|Bifidobacteriales	201174|Actinobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
AKELHBIC_00078	216816.GS08_07800	1.34e-61	189.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4D12C@85004|Bifidobacteriales	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
AKELHBIC_00079	216816.GS08_07805	2.77e-290	793.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4CZ5D@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
AKELHBIC_00080	702459.BBPR_1469	5.93e-287	788.0	COG0577@1|root,COG0577@2|Bacteria,2I99G@201174|Actinobacteria,4D0H6@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
AKELHBIC_00081	326426.Bbr_1559	1.78e-266	733.0	COG0577@1|root,COG0577@2|Bacteria,2IA7B@201174|Actinobacteria,4CZJM@85004|Bifidobacteriales	201174|Actinobacteria	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
AKELHBIC_00082	216816.GS08_02130	2.4e-143	405.0	COG1136@1|root,COG1136@2|Bacteria,2I7UV@201174|Actinobacteria,4CZ1C@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	vex	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_00083	216816.GS08_08605	2.08e-127	361.0	COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,4CZWM@85004|Bifidobacteriales	201174|Actinobacteria	T	low molecular weight	ptpA	GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
AKELHBIC_00084	216816.GS08_08610	6.93e-161	450.0	COG0262@1|root,COG0262@2|Bacteria,2IM1S@201174|Actinobacteria,4CZM1@85004|Bifidobacteriales	201174|Actinobacteria	H	dihydrofolate reductase	folA	GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070401,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2763c	DHFR_1
AKELHBIC_00086	216816.GS08_08615	9.68e-221	607.0	COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria,4CZQ3@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
AKELHBIC_00087	216816.GS08_08620	9.14e-96	278.0	COG1765@1|root,COG1765@2|Bacteria,2IIK7@201174|Actinobacteria,4D0PB@85004|Bifidobacteriales	201174|Actinobacteria	O	OsmC-like protein	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	OsmC
AKELHBIC_00088	216816.GS08_08625	3.06e-238	656.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4CZ6V@85004|Bifidobacteriales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
AKELHBIC_00089	216816.GS08_08630	1.33e-139	398.0	COG0791@1|root,COG0791@2|Bacteria,2GJX7@201174|Actinobacteria,4D01Q@85004|Bifidobacteriales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,PG_binding_1,SLT
AKELHBIC_00090	216816.GS08_08635	1.38e-124	359.0	COG0791@1|root,COG0791@2|Bacteria,2IBQZ@201174|Actinobacteria,4CYXI@85004|Bifidobacteriales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
AKELHBIC_00091	216816.GS08_08640	2.41e-210	583.0	COG3942@1|root,COG3942@2|Bacteria,2GP2A@201174|Actinobacteria,4CYXV@85004|Bifidobacteriales	201174|Actinobacteria	S	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
AKELHBIC_00092	216816.GS08_08645	4.58e-269	737.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4CZ94@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
AKELHBIC_00093	216816.GS08_08650	1.97e-50	160.0	2EG1H@1|root,339TH@2|Bacteria,2IQTR@201174|Actinobacteria,4D16E@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2530
AKELHBIC_00094	216816.GS08_08655	6.48e-254	700.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CZIM@85004|Bifidobacteriales	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	senX3	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
AKELHBIC_00095	216816.GS08_08660	1.05e-148	419.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4CZ9B@85004|Bifidobacteriales	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0016020,GO:0019220,GO:0019222,GO:0022611,GO:0031323,GO:0031324,GO:0032502,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042221,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044444,GO:0044464,GO:0045936,GO:0046677,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:0071944,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
AKELHBIC_00096	216816.GS08_08665	3.69e-178	496.0	COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria,4CZMF@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
AKELHBIC_00097	216816.GS08_08670	1.16e-214	594.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4CZHQ@85004|Bifidobacteriales	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
AKELHBIC_00098	216816.GS08_08675	0.0	1102.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CZHM@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0008150,GO:0040007	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
AKELHBIC_00100	326426.Bbr_1577	2.71e-262	721.0	COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4CZ46@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08156,ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.14,2.A.1.2.65	-	-	MFS_1
AKELHBIC_00101	1437610.BREU_1768	0.0	2047.0	COG0671@1|root,COG0737@1|root,COG0671@2|Bacteria,COG0737@2|Bacteria,2I4ZG@201174|Actinobacteria,4CZ80@85004|Bifidobacteriales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Metallophos,PAP2
AKELHBIC_00102	1437610.BREU_1769	0.0	1001.0	COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria,4CZTS@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,TPR_12
AKELHBIC_00103	216816.GS08_08695	9.45e-145	408.0	2DM2Z@1|root,31HGC@2|Bacteria,2GKMX@201174|Actinobacteria,4CZJ9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4125)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4125
AKELHBIC_00104	216816.GS08_08700	0.0	974.0	COG1073@1|root,COG1073@2|Bacteria,2H036@201174|Actinobacteria,4CYRR@85004|Bifidobacteriales	201174|Actinobacteria	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Hydrolase_4,Peptidase_S9
AKELHBIC_00105	216816.GS08_08705	5.55e-105	309.0	2BIES@1|root,32CM6@2|Bacteria,2GSGC@201174|Actinobacteria,4D1KF@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00106	216816.GS08_08710	4.43e-234	646.0	COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria,4CZZT@85004|Bifidobacteriales	201174|Actinobacteria	KT	PspC domain	pspC	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
AKELHBIC_00107	216816.GS08_08715	2.94e-288	789.0	COG1983@1|root,COG4585@1|root,COG1983@2|Bacteria,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4CZ2U@85004|Bifidobacteriales	201174|Actinobacteria	KT	PspC domain	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
AKELHBIC_00108	326426.Bbr_1584	2.35e-143	406.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4CZW8@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
AKELHBIC_00109	1437610.BREU_1776	9.84e-237	652.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4CZDB@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
AKELHBIC_00110	216816.GS08_08730	0.0	1039.0	COG4468@1|root,COG4468@2|Bacteria,2HNCF@201174|Actinobacteria,4CZT3@85004|Bifidobacteriales	201174|Actinobacteria	G	UDP-glucose--hexose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
AKELHBIC_00111	216816.GS08_08735	8.84e-245	674.0	COG2334@1|root,COG2334@2|Bacteria,2I8JD@201174|Actinobacteria,4D06K@85004|Bifidobacteriales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.162	ko:K13059	-	-	R08962	RC00002,RC00078	ko00000,ko01000	-	-	-	APH
AKELHBIC_00112	216816.GS08_08740	0.0	1542.0	COG5426@1|root,COG5426@2|Bacteria,2GN2A@201174|Actinobacteria,4CYZB@85004|Bifidobacteriales	201174|Actinobacteria	S	Lacto-N-biose phosphorylase C-terminal domain	gnpA	-	2.4.1.211	ko:K15533	-	-	-	-	ko00000,ko01000	-	-	-	LBP_C,LBP_M,Lact_bio_phlase
AKELHBIC_00113	216816.GS08_08745	7.69e-206	572.0	COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4CYV5@85004|Bifidobacteriales	201174|Actinobacteria	G	ABC transporter permease	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AKELHBIC_00114	326426.Bbr_1589	1.79e-219	607.0	COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZX2@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AKELHBIC_00115	216816.GS08_08755	2.4e-314	856.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CZ88@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
AKELHBIC_00117	216816.GS08_08820	8.5e-303	826.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CZ40@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
AKELHBIC_00118	216816.GS08_08825	4.92e-266	730.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4CYTC@85004|Bifidobacteriales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
AKELHBIC_00119	326426.Bbr_1593	1.52e-103	305.0	COG3711@1|root,COG3711@2|Bacteria,2I8K8@201174|Actinobacteria,4D08T@85004|Bifidobacteriales	201174|Actinobacteria	K	CAT RNA binding domain	arbG	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD,PTS-HPr
AKELHBIC_00120	326426.Bbr_1593	5.22e-66	207.0	COG3711@1|root,COG3711@2|Bacteria,2I8K8@201174|Actinobacteria,4D08T@85004|Bifidobacteriales	201174|Actinobacteria	K	CAT RNA binding domain	arbG	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD,PTS-HPr
AKELHBIC_00121	326426.Bbr_1594	0.0	1243.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,2GK6B@201174|Actinobacteria,4CZR7@85004|Bifidobacteriales	201174|Actinobacteria	G	pts system, glucose-specific IIABC component	ptsG	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
AKELHBIC_00122	216816.GS08_08845	0.0	1120.0	COG0033@1|root,COG0033@2|Bacteria,2H1PI@201174|Actinobacteria,4CZ7X@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
AKELHBIC_00123	216816.GS08_08850	1.6e-250	689.0	COG2852@1|root,COG2852@2|Bacteria,2HTNX@201174|Actinobacteria,4D0CP@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00124	216816.GS08_08855	3.69e-90	265.0	COG1959@1|root,COG1959@2|Bacteria,2IKDG@201174|Actinobacteria,4D0YZ@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
AKELHBIC_00125	216816.GS08_08860	0.0	990.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4CZZF@85004|Bifidobacteriales	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	merA	-	1.16.1.1	ko:K00520,ko:K21739	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
AKELHBIC_00127	216816.GS08_08870	6.54e-191	530.0	COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4CZGC@85004|Bifidobacteriales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF4440,RNase_H
AKELHBIC_00128	216816.GS08_08875	1.44e-159	447.0	COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria,4CZDH@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
AKELHBIC_00129	1147128.BAST_1307	5.05e-07	46.6	29UT5@1|root,30G5G@2|Bacteria,2GXCZ@201174|Actinobacteria,4D1N2@85004|Bifidobacteriales	201174|Actinobacteria	S	Mitochondrial domain of unknown function (DUF1713)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1713
AKELHBIC_00130	216816.GS08_08885	1.66e-129	370.0	2EHBK@1|root,33B3F@2|Bacteria,2ICD4@201174|Actinobacteria,4CZY5@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00131	216816.GS08_08890	0.0	954.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CZE1@85004|Bifidobacteriales	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
AKELHBIC_00132	216816.GS08_08895	2.79e-276	754.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CYXT@85004|Bifidobacteriales	201174|Actinobacteria	H	riboflavin kinase	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
AKELHBIC_00133	216816.GS08_08900	1.53e-266	731.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4CZED@85004|Bifidobacteriales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
AKELHBIC_00134	216816.GS08_08905	6.1e-95	278.0	COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria,4CZZZ@85004|Bifidobacteriales	201174|Actinobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
AKELHBIC_00135	216816.GS08_08910	0.0	1554.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CZ4B@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
AKELHBIC_00136	216816.GS08_08915	1.03e-241	665.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CYTW@85004|Bifidobacteriales	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
AKELHBIC_00137	216816.GS08_08920	2.18e-159	448.0	2B54U@1|root,31XYD@2|Bacteria,2HXKT@201174|Actinobacteria,4D0IH@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00138	547043.BIFPSEUDO_03224	1e-310	849.0	COG1653@1|root,COG1653@2|Bacteria,2I5GP@201174|Actinobacteria,4D2XQ@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
AKELHBIC_00139	547043.BIFPSEUDO_03225	8.88e-221	610.0	COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4CZTQ@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AKELHBIC_00140	547043.BIFPSEUDO_03226	3.29e-205	569.0	COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZW4@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AKELHBIC_00141	216816.GS08_01605	2.94e-260	712.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZ5C@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives	tnp3503b	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00142	216816.GS08_00995	7.01e-229	632.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZTH@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00144	1437610.BREU_0640	2.24e-155	446.0	COG1373@1|root,COG1373@2|Bacteria,2GK4E@201174|Actinobacteria,4CZX6@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_00145	216816.GS08_08940	4.01e-192	533.0	COG1305@1|root,COG1305@2|Bacteria,2GN5D@201174|Actinobacteria,4CZBJ@85004|Bifidobacteriales	201174|Actinobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
AKELHBIC_00146	216816.GS08_08945	0.0	1436.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4D061@85004|Bifidobacteriales	201174|Actinobacteria	S	A circularly permuted ATPgrasp	gcs2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	Alpha-E,CP_ATPgrasp_1,CP_ATPgrasp_2,GCS2
AKELHBIC_00147	216816.GS08_08955	2.75e-213	589.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CZ8H@85004|Bifidobacteriales	201174|Actinobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
AKELHBIC_00148	326426.Bbr_1614	1.83e-86	258.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4D0PZ@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
AKELHBIC_00149	216816.GS08_08965	4.01e-236	649.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CZEN@85004|Bifidobacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
AKELHBIC_00150	216816.GS08_08970	7.34e-86	253.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4D0PJ@85004|Bifidobacteriales	201174|Actinobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
AKELHBIC_00151	326426.Bbr_1617	1.16e-81	242.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4D0PQ@85004|Bifidobacteriales	201174|Actinobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
AKELHBIC_00152	158787.BSCA_1163	1.47e-20	81.3	COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria,4D1NT@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
AKELHBIC_00153	1435051.BMOU_1728	6.91e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4D16H@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
AKELHBIC_00154	216816.GS08_08990	7.36e-128	363.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CZ7Z@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
AKELHBIC_00155	216816.GS08_08995	1.87e-316	862.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CYWU@85004|Bifidobacteriales	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
AKELHBIC_00156	216816.GS08_09000	1.52e-98	286.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4D0R9@85004|Bifidobacteriales	201174|Actinobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
AKELHBIC_00157	216816.GS08_09005	4.64e-36	122.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4D1EZ@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L30p/L7e	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
AKELHBIC_00158	216816.GS08_09010	2.82e-128	369.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CZCD@85004|Bifidobacteriales	201174|Actinobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
AKELHBIC_00159	216816.GS08_09015	3.43e-75	226.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4D0WE@85004|Bifidobacteriales	201174|Actinobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
AKELHBIC_00160	216816.GS08_09020	7.72e-122	348.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CYQV@85004|Bifidobacteriales	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
AKELHBIC_00161	1437610.BREU_0623	3.17e-90	264.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4D0P6@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
AKELHBIC_00162	1437609.BCAL_1317	7.06e-40	131.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4D177@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
AKELHBIC_00163	216816.GS08_09035	2.77e-134	380.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CZCA@85004|Bifidobacteriales	201174|Actinobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
AKELHBIC_00164	216816.GS08_09040	1.09e-68	208.0	COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4D10I@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
AKELHBIC_00165	216816.GS08_09045	2.55e-79	236.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4D0VI@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
AKELHBIC_00166	216816.GS08_09050	1.11e-54	171.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4D10N@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
AKELHBIC_00167	216816.GS08_09055	1.97e-49	157.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,4D181@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
AKELHBIC_00168	216816.GS08_09060	3.85e-98	285.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4D0Q8@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
AKELHBIC_00169	216816.GS08_09065	9.27e-162	456.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CYQN@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
AKELHBIC_00170	216816.GS08_09070	1.55e-74	223.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4D0UZ@85004|Bifidobacteriales	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
AKELHBIC_00171	1437608.BBIA_2303	1.4e-62	191.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4D105@85004|Bifidobacteriales	201174|Actinobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
AKELHBIC_00172	216816.GS08_09080	1.34e-195	542.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CZ5U@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
AKELHBIC_00173	158787.BSCA_1142	8.86e-62	189.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4D11N@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
AKELHBIC_00174	216816.GS08_09090	9.39e-149	419.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4CZSA@85004|Bifidobacteriales	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
AKELHBIC_00175	216816.GS08_09095	1.57e-149	421.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CYQD@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
AKELHBIC_00176	1437600.JDUI01000009_gene364	9.35e-68	205.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4D0UT@85004|Bifidobacteriales	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
AKELHBIC_00177	216816.GS08_09105	2.4e-183	509.0	COG3527@1|root,COG3527@2|Bacteria,2IBRH@201174|Actinobacteria,4D0BN@85004|Bifidobacteriales	201174|Actinobacteria	H	Alpha-acetolactate decarboxylase	budA	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	AAL_decarboxy
AKELHBIC_00178	216816.GS08_09110	5.03e-206	572.0	28NT3@1|root,2ZBRV@2|Bacteria,2IIC3@201174|Actinobacteria,4D0MQ@85004|Bifidobacteriales	201174|Actinobacteria	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
AKELHBIC_00179	216816.GS08_09115	0.0	1783.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales	201174|Actinobacteria	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	-	1.1.1.1,1.2.1.10,1.2.1.81	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
AKELHBIC_00180	216816.GS08_09120	6.23e-287	783.0	COG1940@1|root,COG1940@2|Bacteria,2I7R8@201174|Actinobacteria,4CZZ7@85004|Bifidobacteriales	201174|Actinobacteria	GK	transcriptional repressor of nag (N-acetylglucosamine) operon K02565	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR,ROK
AKELHBIC_00181	216816.GS08_09125	0.0	1700.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4CYZ1@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
AKELHBIC_00182	216816.GS08_09130	9.6e-106	306.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CZ9Y@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
AKELHBIC_00183	216816.GS08_09135	3.75e-103	298.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4D0PV@85004|Bifidobacteriales	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
AKELHBIC_00184	216816.GS08_09140	0.0	1436.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CZC7@85004|Bifidobacteriales	201174|Actinobacteria	G	4-alpha-glucanotransferase	malQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
AKELHBIC_00185	216816.GS08_09145	2.6e-141	402.0	2BMRI@1|root,32GAY@2|Bacteria,2GMIA@201174|Actinobacteria,4CZFZ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LRV
AKELHBIC_00186	216816.GS08_09150	2.58e-139	395.0	COG1739@1|root,COG1739@2|Bacteria,2GMM4@201174|Actinobacteria,4CZH8@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterized protein family UPF0029	yigZ	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
AKELHBIC_00187	216816.GS08_09155	8.79e-239	657.0	COG0111@1|root,COG0111@2|Bacteria,2GKTT@201174|Actinobacteria,4CZRS@85004|Bifidobacteriales	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	pdxB	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
AKELHBIC_00189	216816.GS08_09175	2.25e-296	812.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4CZHT@85004|Bifidobacteriales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
AKELHBIC_00190	216816.GS08_09180	3.6e-284	778.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CZ91@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class I and II	dapC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
AKELHBIC_00191	216816.GS08_09185	1.57e-79	235.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4D11B@85004|Bifidobacteriales	201174|Actinobacteria	C	4Fe-4S binding domain	fdxA	GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4
AKELHBIC_00192	216816.GS08_09190	0.0	955.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4CYZA@85004|Bifidobacteriales	201174|Actinobacteria	E	aromatic amino acid transport protein AroP K03293	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
AKELHBIC_00193	216816.GS08_09195	1.17e-287	786.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4CZSJ@85004|Bifidobacteriales	201174|Actinobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
AKELHBIC_00194	1437609.BCAL_1264	1.03e-34	118.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4D1EA@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
AKELHBIC_00198	1437610.BREU_0582	1.27e-49	169.0	COG0626@1|root,COG0626@2|Bacteria,2GNZH@201174|Actinobacteria,4D04I@85004|Bifidobacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	megL	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
AKELHBIC_00199	216816.GS08_09230	6.02e-64	195.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4D101@85004|Bifidobacteriales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
AKELHBIC_00200	216816.GS08_09235	2.13e-280	774.0	2E03N@1|root,32VSG@2|Bacteria,2GQE4@201174|Actinobacteria,4CYUX@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00201	216816.GS08_09240	1.15e-164	459.0	COG1670@1|root,COG1670@2|Bacteria,2HAFI@201174|Actinobacteria,4CZRR@85004|Bifidobacteriales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
AKELHBIC_00202	216816.GS08_09245	4.76e-168	470.0	COG0212@1|root,COG0212@2|Bacteria,2IKWR@201174|Actinobacteria,4D12B@85004|Bifidobacteriales	201174|Actinobacteria	H	5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
AKELHBIC_00203	216816.GS08_09250	2.17e-43	140.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4D1ES@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
AKELHBIC_00204	216816.GS08_09255	1.02e-120	347.0	COG1261@1|root,COG1261@2|Bacteria,2IIYF@201174|Actinobacteria,4D0YD@85004|Bifidobacteriales	201174|Actinobacteria	NO	SAF	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,SAF
AKELHBIC_00205	216816.GS08_09260	2.09e-41	135.0	2B18D@1|root,31TNU@2|Bacteria,2GSR6@201174|Actinobacteria,4D1ET@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00206	216816.GS08_09265	0.0	2298.0	COG1112@1|root,COG1112@2|Bacteria,2GKJW@201174|Actinobacteria,4CYY9@85004|Bifidobacteriales	201174|Actinobacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF4011
AKELHBIC_00207	216816.GS08_09270	1.64e-243	679.0	COG1716@1|root,COG1716@2|Bacteria,2GIT6@201174|Actinobacteria,4CYX9@85004|Bifidobacteriales	201174|Actinobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
AKELHBIC_00208	216816.GS08_09275	1.74e-63	196.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4D0W2@85004|Bifidobacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
AKELHBIC_00209	216816.GS08_09280	2.41e-113	326.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4CZFP@85004|Bifidobacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
AKELHBIC_00210	216816.GS08_09285	1.36e-179	502.0	COG1073@1|root,COG1073@2|Bacteria,2HZF3@201174|Actinobacteria,4D06X@85004|Bifidobacteriales	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00211	216816.GS08_09290	4.51e-314	858.0	COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria,4CZHD@85004|Bifidobacteriales	201174|Actinobacteria	S	Permease family	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
AKELHBIC_00212	216816.GS08_09295	0.0	1536.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CYSW@85004|Bifidobacteriales	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
AKELHBIC_00213	216816.GS08_09300	1.44e-56	176.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4D10E@85004|Bifidobacteriales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
AKELHBIC_00214	216816.GS08_09305	3.14e-239	658.0	COG2274@1|root,COG2274@2|Bacteria,2GNB5@201174|Actinobacteria,4D1BI@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
AKELHBIC_00215	216816.GS08_09310	3.58e-198	548.0	COG1131@1|root,COG1131@2|Bacteria,2GKWE@201174|Actinobacteria,4CZUM@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
AKELHBIC_00217	216816.GS08_09320	2.87e-101	298.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_00218	1437610.BREU_1625	1.43e-123	363.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_00219	216816.GS08_09325	1.22e-149	422.0	2B37S@1|root,31VVT@2|Bacteria,2IDBE@201174|Actinobacteria,4CZJV@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00220	326426.Bbr_0363	4.38e-139	395.0	2C89M@1|root,332IE@2|Bacteria,2IPVJ@201174|Actinobacteria,4D133@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00222	216816.GS08_09370	9.62e-121	345.0	COG0736@1|root,COG0736@2|Bacteria,2HZNB@201174|Actinobacteria,4D10J@85004|Bifidobacteriales	201174|Actinobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
AKELHBIC_00223	216816.GS08_09385	0.0	6076.0	COG0304@1|root,COG0331@1|root,COG2030@1|root,COG4981@1|root,COG0304@2|Bacteria,COG0331@2|Bacteria,COG2030@2|Bacteria,COG4981@2|Bacteria,2GIY4@201174|Actinobacteria,4CYXJ@85004|Bifidobacteriales	201174|Actinobacteria	I	Beta-ketoacyl synthase, C-terminal domain	fas	-	-	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	M00082,M00083	R01624,R01626,R04355,R04428,R04429,R04533,R04534,R04535,R04536,R04537,R04543,R04544,R04566,R04568,R04724,R04726,R04952,R04953,R04954,R04955,R04957,R04958,R04960,R04961,R04963,R04964,R04965,R04966,R04968,R04969,R07762,R07763,R07764,R07765,R10700	RC00004,RC00029,RC00039,RC00052,RC00076,RC00117,RC00831,RC01095,RC02727,RC02728,RC02729,RC02857,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1,DUF1729,Ketoacyl-synt_C,MaoC_dehydratas,SAT,ketoacyl-synt
AKELHBIC_00224	216816.GS08_09390	0.0	1031.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CYSI@85004|Bifidobacteriales	201174|Actinobacteria	I	Carboxyl transferase domain	pccB	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
AKELHBIC_00225	326426.Bbr_1721	0.0	1215.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4CYU4@85004|Bifidobacteriales	201174|Actinobacteria	I	Carbamoyl-phosphate synthase L chain, ATP binding domain protein	accC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
AKELHBIC_00226	216816.GS08_09400	7.96e-17	80.1	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4D0BB@85004|Bifidobacteriales	201174|Actinobacteria	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
AKELHBIC_00227	216816.GS08_09405	4.35e-188	525.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4D0R8@85004|Bifidobacteriales	201174|Actinobacteria	H	Biotin/lipoate A/B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
AKELHBIC_00228	216816.GS08_09410	0.0	1323.0	2DX0J@1|root,342TV@2|Bacteria,2H683@201174|Actinobacteria,4CZAG@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00229	216816.GS08_09415	4.63e-179	501.0	COG2508@1|root,COG2508@2|Bacteria,2GN0S@201174|Actinobacteria,4CYXU@85004|Bifidobacteriales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
AKELHBIC_00230	216816.GS08_09420	3.5e-169	473.0	COG1414@1|root,COG1414@2|Bacteria,2IMT9@201174|Actinobacteria,4D1ZU@85004|Bifidobacteriales	201174|Actinobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
AKELHBIC_00231	216816.GS08_09425	7.19e-196	543.0	COG1414@1|root,COG1414@2|Bacteria,2GPS1@201174|Actinobacteria,4D25V@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
AKELHBIC_00232	445975.COLSTE_02537	1.52e-35	142.0	2AHMW@1|root,317ZU@2|Bacteria,2HC22@201174|Actinobacteria	201174|Actinobacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00233	1410622.JNKY01000003_gene1884	3.31e-06	47.4	2DER4@1|root,2ZNXD@2|Bacteria,1W32Q@1239|Firmicutes,24UYB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00234	216816.GS08_09445	3.53e-159	446.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CZFR@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
AKELHBIC_00235	216816.GS08_09450	5e-96	280.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4D0PA@85004|Bifidobacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
AKELHBIC_00236	216816.GS08_09455	2.27e-193	538.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CYSH@85004|Bifidobacteriales	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
AKELHBIC_00237	216816.GS08_09460	2.45e-44	144.0	COG0690@1|root,COG0690@2|Bacteria,2HZQC@201174|Actinobacteria,4D18K@85004|Bifidobacteriales	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
AKELHBIC_00239	216816.GS08_09470	3.38e-293	800.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZFY@85004|Bifidobacteriales	201174|Actinobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
AKELHBIC_00240	216816.GS08_09475	6.89e-258	708.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4CZ2B@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
AKELHBIC_00241	216816.GS08_09480	0.0	1091.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4CYWD@85004|Bifidobacteriales	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
AKELHBIC_00242	216816.GS08_09485	3.99e-53	166.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4D19N@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal L27 protein	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
AKELHBIC_00243	216816.GS08_09490	4.13e-62	191.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4D10B@85004|Bifidobacteriales	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
AKELHBIC_00244	216816.GS08_09495	0.0	1336.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CYQT@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
AKELHBIC_00245	216816.GS08_09500	3.33e-290	793.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4CZ9K@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase dimerisation domain	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
AKELHBIC_00246	216816.GS08_09505	6.17e-211	584.0	COG0679@1|root,COG0679@2|Bacteria,2GNIA@201174|Actinobacteria,4CZFX@85004|Bifidobacteriales	201174|Actinobacteria	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
AKELHBIC_00247	1437609.BCAL_2123	9.59e-101	292.0	COG4154@1|root,COG4154@2|Bacteria,2INSY@201174|Actinobacteria,4D122@85004|Bifidobacteriales	201174|Actinobacteria	G	RbsD / FucU transport protein family	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
AKELHBIC_00248	216816.GS08_09515	6.4e-188	521.0	COG3618@1|root,COG3618@2|Bacteria,2HRH9@201174|Actinobacteria,4CZX0@85004|Bifidobacteriales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
AKELHBIC_00249	1437609.BCAL_2120	1.26e-263	727.0	COG0738@1|root,COG0738@2|Bacteria,2GJ5D@201174|Actinobacteria,4D02K@85004|Bifidobacteriales	201174|Actinobacteria	G	Major Facilitator Superfamily	fucP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
AKELHBIC_00250	216816.GS08_09525	1.74e-180	503.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CZXI@85004|Bifidobacteriales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100,1.1.1.413	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R08926,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
AKELHBIC_00251	216816.GS08_09530	1.96e-312	850.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4D0EI@85004|Bifidobacteriales	201174|Actinobacteria	M	Enolase C-terminal domain-like	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
AKELHBIC_00252	326426.Bbr_1745	2.48e-231	638.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZI0@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00253	216816.GS08_09540	0.0	882.0	COG0577@1|root,COG0577@2|Bacteria,2GKF3@201174|Actinobacteria,4D03X@85004|Bifidobacteriales	201174|Actinobacteria	V	Efflux ABC transporter, permease protein	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
AKELHBIC_00254	216816.GS08_09545	1.19e-182	513.0	COG1136@1|root,COG1136@2|Bacteria,2GM25@201174|Actinobacteria,4D0FV@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_00256	1437608.BBIA_1347	2.92e-23	90.1	2B12Y@1|root,30DWC@2|Bacteria,2GWJ2@201174|Actinobacteria,4D1TU@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
AKELHBIC_00257	326426.Bbr_1748	3.14e-11	60.8	COG0454@1|root,COG0454@2|Bacteria,2IC6K@201174|Actinobacteria,4D0SR@85004|Bifidobacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
AKELHBIC_00258	216816.GS08_09560	0.0	957.0	COG0424@1|root,COG1051@1|root,COG0424@2|Bacteria,COG1051@2|Bacteria,2GNI0@201174|Actinobacteria,4CZXF@85004|Bifidobacteriales	201174|Actinobacteria	DF	Maf-like protein	maf	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf,NUDIX
AKELHBIC_00259	216816.GS08_09565	3.42e-259	711.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4CZN0@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
AKELHBIC_00260	216816.GS08_09570	1.9e-295	808.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4CZVD@85004|Bifidobacteriales	201174|Actinobacteria	E	Homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
AKELHBIC_00261	216816.GS08_09575	0.0	1004.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4CYRG@85004|Bifidobacteriales	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
AKELHBIC_00262	216816.GS08_09580	0.0	1214.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CZ9J@85004|Bifidobacteriales	201174|Actinobacteria	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
AKELHBIC_00263	216816.GS08_09585	5.36e-219	604.0	COG0583@1|root,COG0583@2|Bacteria,2GKT0@201174|Actinobacteria,4D04F@85004|Bifidobacteriales	201174|Actinobacteria	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
AKELHBIC_00264	216816.GS08_09590	1.48e-311	847.0	COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4CZFH@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase, class I II	-	-	4.4.1.8	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
AKELHBIC_00265	326426.Bbr_1757	0.0	875.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CZN7@85004|Bifidobacteriales	201174|Actinobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
AKELHBIC_00266	216816.GS08_09600	0.0	878.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4CZXP@85004|Bifidobacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	nox	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Reductase_C
AKELHBIC_00267	561180.BIFGAL_02795	1.09e-141	423.0	COG0675@1|root,COG0675@2|Bacteria,2HZNV@201174|Actinobacteria,4D13C@85004|Bifidobacteriales	201174|Actinobacteria	L	Putative transposase DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
AKELHBIC_00268	1437609.BCAL_1374	1.55e-97	288.0	COG2452@1|root,COG2452@2|Bacteria,2INA9@201174|Actinobacteria,4D156@85004|Bifidobacteriales	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
AKELHBIC_00269	216816.GS08_09605	4.22e-267	731.0	COG0167@1|root,COG0167@2|Bacteria,2GJMN@201174|Actinobacteria,4CZKM@85004|Bifidobacteriales	201174|Actinobacteria	F	Dihydroorotate dehydrogenase	pyr	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
AKELHBIC_00270	216816.GS08_09610	2.61e-170	474.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CZ2F@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
AKELHBIC_00271	216816.GS08_09615	0.0	925.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4CYUC@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
AKELHBIC_00272	216816.GS08_09620	5.17e-179	499.0	COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,4CZ9D@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulator, IclR family, C-terminal domain protein	ltbR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
AKELHBIC_00273	216816.GS08_09625	1.52e-306	837.0	COG1409@1|root,COG1409@2|Bacteria,2HRDZ@201174|Actinobacteria,4CYQR@85004|Bifidobacteriales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
AKELHBIC_00274	216816.GS08_09630	0.0	1461.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4CYXH@85004|Bifidobacteriales	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
AKELHBIC_00275	216816.GS08_09635	5.63e-275	753.0	COG0494@1|root,COG2062@1|root,COG0494@2|Bacteria,COG2062@2|Bacteria,2GNRV@201174|Actinobacteria,4CZ90@85004|Bifidobacteriales	201174|Actinobacteria	LT	Phosphoglycerate mutase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
AKELHBIC_00276	216816.GS08_09640	3.15e-150	425.0	28MMU@1|root,2ZAXG@2|Bacteria,2HAD5@201174|Actinobacteria,4CZ1Q@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00277	216816.GS08_03905	0.0	900.0	COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location CytoplasmicMembrane, score 10.00	gph	-	-	ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2.2	-	-	MFS_2
AKELHBIC_00278	216816.GS08_03900	0.0	946.0	COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location CytoplasmicMembrane, score 10.00	gph	-	-	ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2.2	-	-	MFS_2
AKELHBIC_00279	216816.GS08_03895	0.0	2101.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CYYS@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3
AKELHBIC_00280	216816.GS08_01720	0.0	1281.0	COG1554@1|root,COG1554@2|Bacteria,2GJXJ@201174|Actinobacteria,4CZZK@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Big_2,Big_3,Glyco_hyd_65N_2
AKELHBIC_00281	216816.GS08_01715	0.0	880.0	COG3669@1|root,COG3669@2|Bacteria,2I650@201174|Actinobacteria,4CZPN@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
AKELHBIC_00282	216816.GS08_01710	4.41e-91	267.0	COG4154@1|root,COG4154@2|Bacteria,2INSY@201174|Actinobacteria,4D122@85004|Bifidobacteriales	201174|Actinobacteria	G	RbsD / FucU transport protein family	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
AKELHBIC_00283	216816.GS08_01705	2.56e-195	543.0	COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4D04B@85004|Bifidobacteriales	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.1.2.28	ko:K22397	ko00040,map00040	-	R01782	RC00307,RC00572	ko00000,ko00001,ko01000	-	-	-	DHDPS
AKELHBIC_00284	216816.GS08_01700	3.01e-181	505.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CZXI@85004|Bifidobacteriales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100,1.1.1.413	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R08926,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
AKELHBIC_00285	547043.BIFPSEUDO_03223	2.28e-310	845.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4D0EI@85004|Bifidobacteriales	201174|Actinobacteria	M	Enolase C-terminal domain-like	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
AKELHBIC_00286	1435051.BMOU_0546	5.99e-123	354.0	COG5578@1|root,COG5578@2|Bacteria,2H1AM@201174|Actinobacteria,4CYSQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
AKELHBIC_00287	1435051.BMOU_0548	1.39e-194	543.0	COG0395@1|root,COG0395@2|Bacteria,2GJPQ@201174|Actinobacteria,4CYTJ@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
AKELHBIC_00288	1435051.BMOU_0549	7.69e-193	539.0	COG4209@1|root,COG4209@2|Bacteria,2GKSR@201174|Actinobacteria,4CZIC@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
AKELHBIC_00289	1435051.BMOU_0550	1.29e-276	768.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_00290	1435051.BMOU_0548	1.39e-194	543.0	COG0395@1|root,COG0395@2|Bacteria,2GJPQ@201174|Actinobacteria,4CYTJ@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
AKELHBIC_00291	1435051.BMOU_0549	7.69e-193	539.0	COG4209@1|root,COG4209@2|Bacteria,2GKSR@201174|Actinobacteria,4CZIC@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
AKELHBIC_00292	1435051.BMOU_0550	8.99e-295	815.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_00293	398513.BBNG_01313	4.81e-151	455.0	COG1470@1|root,COG4409@1|root,COG1470@2|Bacteria,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria,4D02H@85004|Bifidobacteriales	201174|Actinobacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,CW_binding_1,F5_F8_type_C,NPCBM_assoc
AKELHBIC_00294	1688.BCUN_0027	5.02e-173	489.0	COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4D04B@85004|Bifidobacteriales	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	nanA	-	4.1.3.3,4.3.3.7	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01811,R10147	RC00159,RC00600,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
AKELHBIC_00295	1435051.BMOU_0550	1.06e-311	857.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_00296	1435051.BMOU_0550	1.5e-282	784.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_00297	216816.GS08_09660	4.33e-112	330.0	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4CYS4@85004|Bifidobacteriales	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Laminin_G_3
AKELHBIC_00298	216816.GS08_09655	7.65e-101	293.0	COG1576@1|root,COG1576@2|Bacteria,2IJE0@201174|Actinobacteria,4D0P5@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
AKELHBIC_00299	1437610.BREU_1164	8.46e-147	416.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4CYVS@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
AKELHBIC_00300	1437610.BREU_1163	6.73e-271	758.0	COG0671@1|root,COG0671@2|Bacteria,2I4ZG@201174|Actinobacteria,4CZ80@85004|Bifidobacteriales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,Phytase-like
AKELHBIC_00301	1437609.BCAL_1499	6.85e-23	92.4	COG2452@1|root,COG2452@2|Bacteria,2IDNQ@201174|Actinobacteria,4CZVV@85004|Bifidobacteriales	201174|Actinobacteria	L	Resolvase, N terminal domain	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07450	-	-	-	-	ko00000	-	-	-	Resolvase
AKELHBIC_00302	1437610.BREU_0047	6.46e-165	473.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4CZ11@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
AKELHBIC_00303	1435051.BMOU_0550	6.32e-281	780.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_00304	326426.Bbr_1556	2.31e-246	703.0	COG3525@1|root,COG3525@2|Bacteria,2HZCI@201174|Actinobacteria,4CZS1@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
AKELHBIC_00305	595593.JREV01000021_gene1745	2.09e-37	139.0	COG0546@1|root,COG0546@2|Bacteria,2IQ6G@201174|Actinobacteria	201174|Actinobacteria	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAD
AKELHBIC_00306	1415775.U729_2173	4.25e-175	503.0	COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,249GC@186801|Clostridia,36DXR@31979|Clostridiaceae	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
AKELHBIC_00307	1280692.AUJL01000016_gene1145	1.65e-143	423.0	COG0595@1|root,COG0595@2|Bacteria,1V0AV@1239|Firmicutes,24AT4@186801|Clostridia,36EN7@31979|Clostridiaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B_2,RMMBL
AKELHBIC_00308	1415775.U729_2175	5.99e-128	371.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,25C50@186801|Clostridia,36WPD@31979|Clostridiaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
AKELHBIC_00309	1280689.AUJC01000006_gene2765	2.63e-130	380.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,36HHS@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AKELHBIC_00310	1280689.AUJC01000006_gene2766	3.48e-161	462.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,36DYU@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112,ko:K17240	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00599,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.38	-	-	ABC_tran,TOBE_2
AKELHBIC_00311	216816.GS08_07065	3.73e-121	345.0	COG4283@1|root,COG4283@2|Bacteria,2IGS2@201174|Actinobacteria,4D14I@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
AKELHBIC_00312	326426.Bbr_1777	6.4e-149	419.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4CYVS@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
AKELHBIC_00313	216816.GS08_09655	2.19e-100	292.0	COG1576@1|root,COG1576@2|Bacteria,2IJE0@201174|Actinobacteria,4D0P5@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
AKELHBIC_00314	216816.GS08_09660	6.19e-112	332.0	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4CYS4@85004|Bifidobacteriales	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Laminin_G_3
AKELHBIC_00315	1437608.BBIA_0147	9.3e-262	725.0	COG1653@1|root,COG1653@2|Bacteria,2GNYN@201174|Actinobacteria,4D08X@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K17329	ko02010,map02010	M00207,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_00316	1437608.BBIA_0148	7.21e-163	462.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4D29F@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
AKELHBIC_00317	1437608.BBIA_0149	3.65e-167	474.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4D0GQ@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K05814	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
AKELHBIC_00318	1437610.BREU_1166	5.23e-200	560.0	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4CYS4@85004|Bifidobacteriales	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Laminin_G_3
AKELHBIC_00319	216816.GS08_09665	3.38e-199	558.0	COG0008@1|root,COG0008@2|Bacteria,2GKMT@201174|Actinobacteria,4CYRY@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	gluQ	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
AKELHBIC_00320	216816.GS08_09670	0.0	1602.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CZDY@85004|Bifidobacteriales	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
AKELHBIC_00321	216816.GS08_09690	2e-200	554.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4CZH5@85004|Bifidobacteriales	201174|Actinobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
AKELHBIC_00322	702459.BBPR_0285	2.86e-05	50.4	29W7E@1|root,30HSM@2|Bacteria,2HZTK@201174|Actinobacteria,4D1PX@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4854)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4854
AKELHBIC_00323	566552.BIFCAT_01710	1.42e-109	339.0	COG2865@1|root,COG2865@2|Bacteria,2GP7C@201174|Actinobacteria,4CZRD@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
AKELHBIC_00325	216816.GS08_09710	1.85e-282	772.0	COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4CZ2W@85004|Bifidobacteriales	201174|Actinobacteria	M	UDP-galactopyranose mutase	glf	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3809c	GLF,NAD_binding_8
AKELHBIC_00326	1437600.JDUI01000013_gene970	9.39e-231	644.0	COG3934@1|root,COG3934@2|Bacteria,2GNN6@201174|Actinobacteria,4CZEH@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
AKELHBIC_00327	158787.BSCA_1686	9.45e-161	454.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4D014@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AKELHBIC_00328	158787.BSCA_1685	3.37e-154	441.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4D0DM@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K17330	ko02010,map02010	M00207,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.33	-	-	BPD_transp_1
AKELHBIC_00329	158787.BSCA_1802	4.13e-220	617.0	COG1653@1|root,COG1653@2|Bacteria,2GJSR@201174|Actinobacteria,4D08C@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_00330	78346.BRUM_0133	6.38e-88	269.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00331	216816.GS08_09715	1.1e-255	703.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CZZY@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rmlB	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3464	GDP_Man_Dehyd
AKELHBIC_00332	216816.GS08_09720	0.0	973.0	COG1106@1|root,COG1106@2|Bacteria,2IH2Y@201174|Actinobacteria,4D0R4@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23
AKELHBIC_00333	216816.GS08_09725	2.55e-174	486.0	2A74Q@1|root,30W0F@2|Bacteria,2ISJ1@201174|Actinobacteria,4D1A8@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00334	326426.Bbr_0312	2.37e-274	754.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D01G@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00335	566552.BIFCAT_01966	6.78e-85	264.0	COG5263@1|root,COG5263@2|Bacteria,2IBQA@201174|Actinobacteria,4CZYV@85004|Bifidobacteriales	201174|Actinobacteria	M	Cell wall-binding repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
AKELHBIC_00336	518635.BIFANG_02134	9.65e-192	541.0	COG3594@1|root,COG3594@2|Bacteria,2HVW3@201174|Actinobacteria,4D0F5@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
AKELHBIC_00337	566552.BIFCAT_01955	7.47e-267	746.0	2DM53@1|root,31R8Y@2|Bacteria,2IBMY@201174|Actinobacteria,4D0GA@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00338	518635.BIFANG_02137	5.48e-200	559.0	COG1215@1|root,COG1215@2|Bacteria,2GKKV@201174|Actinobacteria,4CZEG@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2,GtrA
AKELHBIC_00339	216816.GS08_09710	1.11e-282	772.0	COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4CZ2W@85004|Bifidobacteriales	201174|Actinobacteria	M	UDP-galactopyranose mutase	glf	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3809c	GLF,NAD_binding_8
AKELHBIC_00340	518635.BIFANG_02121	0.0	1191.0	COG1216@1|root,COG1216@2|Bacteria,2GM9N@201174|Actinobacteria,4CZ30@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyltransferase like family 2	glfT	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009273,GO:0009987,GO:0010383,GO:0016020,GO:0016043,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0022607,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0035250,GO:0035496,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0046483,GO:0052573,GO:0055086,GO:0070589,GO:0070592,GO:0071554,GO:0071555,GO:0071704,GO:0071766,GO:0071769,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901576,GO:1903509	2.4.1.288	ko:K16650	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	iNJ661.Rv3808c	Glyco_tranf_2_3
AKELHBIC_00341	518635.BIFANG_02126	4.91e-286	784.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4CZ1B@85004|Bifidobacteriales	201174|Actinobacteria	GM	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,Wzt_C
AKELHBIC_00342	518635.BIFANG_02127	1.18e-185	520.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4CZ73@85004|Bifidobacteriales	201174|Actinobacteria	U	Transport permease protein	tagG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
AKELHBIC_00343	518635.BIFANG_02128	0.0	1127.0	COG1216@1|root,COG1216@2|Bacteria,2GNJN@201174|Actinobacteria,4CZ2V@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
AKELHBIC_00344	518635.BIFANG_02129	1.81e-230	642.0	COG2327@1|root,COG2327@2|Bacteria,2H0DT@201174|Actinobacteria,4D0FB@85004|Bifidobacteriales	201174|Actinobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
AKELHBIC_00345	518635.BIFANG_02130	0.0	889.0	COG1216@1|root,COG1216@2|Bacteria,2GNJN@201174|Actinobacteria,4CZ2V@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
AKELHBIC_00346	216816.GS08_09810	7.01e-141	397.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CZZY@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3464	GDP_Man_Dehyd
AKELHBIC_00347	216816.GS08_09815	8.25e-255	704.0	COG1835@1|root,COG1835@2|Bacteria,2H65A@201174|Actinobacteria,4D2BH@85004|Bifidobacteriales	201174|Actinobacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00348	216816.GS08_09820	0.0	1297.0	COG2976@1|root,COG2976@2|Bacteria,2GNIS@201174|Actinobacteria,4D2V4@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
AKELHBIC_00349	216816.GS08_09825	1.45e-294	811.0	COG0577@1|root,COG0577@2|Bacteria,2GMGJ@201174|Actinobacteria,4CZBN@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
AKELHBIC_00350	216816.GS08_09830	8.62e-237	655.0	COG1136@1|root,COG1136@2|Bacteria,2GNFW@201174|Actinobacteria,4CZAW@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_00352	216816.GS08_09840	7.18e-170	474.0	COG2206@1|root,COG2206@2|Bacteria,2GNQR@201174|Actinobacteria,4CYT9@85004|Bifidobacteriales	201174|Actinobacteria	T	HD domain	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
AKELHBIC_00353	216816.GS08_09845	1.2e-203	563.0	COG0121@1|root,COG0121@2|Bacteria,2IBFV@201174|Actinobacteria,4CYX2@85004|Bifidobacteriales	201174|Actinobacteria	S	Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6
AKELHBIC_00354	216816.GS08_09850	0.0	1560.0	COG3158@1|root,COG3158@2|Bacteria,2GMPQ@201174|Actinobacteria,4CZM3@85004|Bifidobacteriales	201174|Actinobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
AKELHBIC_00355	216816.GS08_09855	2.72e-237	651.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CYZI@85004|Bifidobacteriales	201174|Actinobacteria	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
AKELHBIC_00357	216816.GS08_09860	2.63e-195	546.0	COG0657@1|root,COG0657@2|Bacteria,2HGIX@201174|Actinobacteria,4CZUK@85004|Bifidobacteriales	201174|Actinobacteria	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
AKELHBIC_00358	1437610.BREU_0420	1.5e-154	455.0	COG0477@1|root,COG0477@2|Bacteria,2HC9X@201174|Actinobacteria,4D2XP@85004|Bifidobacteriales	201174|Actinobacteria	U	Sugar (and other) transporter	gtr	-	-	ko:K08139	ko04113,map04113	-	-	-	ko00000,ko00001,ko02000	2.A.1.1	-	-	Sugar_tr
AKELHBIC_00359	1403948.Q618_VCMC00001G0518	3.77e-79	251.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4D52K@85005|Actinomycetales	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
AKELHBIC_00360	644284.Arch_0331	1.45e-114	333.0	COG3010@1|root,COG3010@2|Bacteria,2GTWV@201174|Actinobacteria,4D3JQ@85005|Actinomycetales	201174|Actinobacteria	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
AKELHBIC_00361	401473.BDP_1318	1.43e-32	129.0	COG2207@1|root,COG2207@2|Bacteria,2I65M@201174|Actinobacteria,4D17X@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
AKELHBIC_00362	1437610.BREU_1848	2.12e-33	125.0	COG1510@1|root,COG3177@1|root,COG1510@2|Bacteria,COG3177@2|Bacteria,2HZGJ@201174|Actinobacteria,4D0D3@85004|Bifidobacteriales	201174|Actinobacteria	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
AKELHBIC_00363	158787.BSCA_1760	1.31e-20	90.9	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2GKW1@201174|Actinobacteria,4CYXY@85004|Bifidobacteriales	201174|Actinobacteria	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
AKELHBIC_00364	1437610.BREU_1219	2.78e-251	690.0	COG3177@1|root,COG3177@2|Bacteria,2IAAQ@201174|Actinobacteria,4CZAM@85004|Bifidobacteriales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
AKELHBIC_00365	1437610.BREU_1220	0.0	1149.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZ32@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AKELHBIC_00366	1437610.BREU_1221	0.0	1243.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4D028@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AKELHBIC_00367	216816.GS08_09990	0.0	924.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4CZTD@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
AKELHBIC_00368	216816.GS08_09995	1.42e-58	181.0	COG1373@1|root,COG1373@2|Bacteria,2GM3Y@201174|Actinobacteria,4CZTJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_00369	216816.GS08_10000	1.23e-257	703.0	COG3507@1|root,COG3507@2|Bacteria,2I2H2@201174|Actinobacteria,4CZDP@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
AKELHBIC_00370	1437610.BREU_2297	2.58e-196	545.0	COG0395@1|root,COG0395@2|Bacteria,2GM2W@201174|Actinobacteria,4D05E@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
AKELHBIC_00371	1437610.BREU_2296	9.38e-229	630.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZCI@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
AKELHBIC_00372	216816.GS08_10015	9.99e-309	840.0	COG1653@1|root,COG1653@2|Bacteria,2HZAD@201174|Actinobacteria,4CZ9S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
AKELHBIC_00373	216816.GS08_10020	3.01e-251	689.0	COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria,4D041@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00374	216816.GS08_10025	0.0	1437.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ6K@85004|Bifidobacteriales	201174|Actinobacteria	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
AKELHBIC_00375	216816.GS08_10030	0.0	923.0	COG1373@1|root,COG1373@2|Bacteria,2HCYQ@201174|Actinobacteria,4D2TP@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_00376	216816.GS08_10035	0.0	884.0	COG0477@1|root,COG0477@2|Bacteria,2I3AP@201174|Actinobacteria,4D0YC@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_00378	216816.GS08_10040	0.0	1116.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria,4CZ3S@85004|Bifidobacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
AKELHBIC_00379	1437610.BREU_2280	0.0	1384.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CYU0@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	oppD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
AKELHBIC_00380	1437610.BREU_2279	4.98e-226	624.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CYQF@85004|Bifidobacteriales	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
AKELHBIC_00381	216816.GS08_10055	8.3e-227	625.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CYS5@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	oppB1	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
AKELHBIC_00382	1437610.BREU_2276	0.0	978.0	COG3579@1|root,COG3579@2|Bacteria,2HCVR@201174|Actinobacteria,4CZD8@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase C1-like family	-	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1_2
AKELHBIC_00383	216816.GS08_10065	1.49e-217	602.0	COG2852@1|root,COG2852@2|Bacteria,2HTNX@201174|Actinobacteria,4D0CP@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00384	1437610.BREU_2271	3.2e-64	196.0	2AWD6@1|root,31N94@2|Bacteria,2IP9F@201174|Actinobacteria,4D137@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00385	216816.GS08_10075	0.0	1188.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CZ20@85004|Bifidobacteriales	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
AKELHBIC_00386	216816.GS08_10080	5.09e-148	416.0	2AU2N@1|root,31JNZ@2|Bacteria,2IJNI@201174|Actinobacteria,4D047@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00387	1437610.BREU_2330	2.34e-38	132.0	2B10P@1|root,31TDZ@2|Bacteria,2GS86@201174|Actinobacteria,4D1GZ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00388	216816.GS08_10090	4.41e-235	648.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CZ03@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
AKELHBIC_00390	326426.Bbr_1824	4.86e-313	856.0	COG2211@1|root,COG2211@2|Bacteria,2HZ98@201174|Actinobacteria,4CZ0N@85004|Bifidobacteriales	201174|Actinobacteria	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
AKELHBIC_00391	216816.GS08_10105	3.06e-238	656.0	COG1477@1|root,COG1477@2|Bacteria,2H8YU@201174|Actinobacteria,4CZW7@85004|Bifidobacteriales	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
AKELHBIC_00392	216816.GS08_10110	0.0	1144.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZTU@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AKELHBIC_00393	216816.GS08_10115	0.0	1107.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CYYV@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AKELHBIC_00394	216816.GS08_10120	2.11e-101	296.0	COG1846@1|root,COG1846@2|Bacteria,2IMKE@201174|Actinobacteria,4CYZZ@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34,MarR
AKELHBIC_00395	216816.GS08_10145	0.0	926.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4CZAY@85004|Bifidobacteriales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K03293	-	-	-	-	ko00000	2.A.3.1	-	-	AA_permease
AKELHBIC_00396	216816.GS08_10205	0.0	1768.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,2I2FK@201174|Actinobacteria,4CZJR@85004|Bifidobacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
AKELHBIC_00397	216816.GS08_10210	3.65e-158	444.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4CYT2@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_00398	1437610.BREU_2258	0.0	893.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4CZ4X@85004|Bifidobacteriales	201174|Actinobacteria	E	aromatic amino acid transport protein AroP K03293	aroP	-	-	ko:K03293,ko:K11732	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.1	-	-	AA_permease
AKELHBIC_00399	216816.GS08_10235	1.36e-133	380.0	COG5578@1|root,COG5578@2|Bacteria,2IBKF@201174|Actinobacteria,4D0E0@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
AKELHBIC_00400	216816.GS08_10240	1.06e-194	540.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4CYZ9@85004|Bifidobacteriales	201174|Actinobacteria	G	ABC transporter permease	-	-	-	ko:K02026,ko:K10119	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
AKELHBIC_00401	216816.GS08_10245	9.46e-200	553.0	COG1175@1|root,COG1175@2|Bacteria,2I330@201174|Actinobacteria,4CZJC@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	msmF	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
AKELHBIC_00402	216816.GS08_10250	7.73e-233	642.0	COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4CZ1Y@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00403	216816.GS08_10255	0.0	870.0	COG1653@1|root,COG1653@2|Bacteria,2GWCY@201174|Actinobacteria,4CYWG@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	amyE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
AKELHBIC_00404	216816.GS08_10260	7.2e-176	489.0	COG0406@1|root,COG0406@2|Bacteria,2GNRS@201174|Actinobacteria,4CZD2@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	gpm2	GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
AKELHBIC_00405	216816.GS08_10265	5.29e-78	233.0	2B5DJ@1|root,31Y80@2|Bacteria,2IRRR@201174|Actinobacteria,4D1E6@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4235
AKELHBIC_00406	216816.GS08_10270	2.58e-180	502.0	COG0778@1|root,COG0778@2|Bacteria,2I65Z@201174|Actinobacteria,4CZ5R@85004|Bifidobacteriales	201174|Actinobacteria	C	Nitroreductase family	nfrA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
AKELHBIC_00407	216816.GS08_10275	0.0	1427.0	COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ9R@85004|Bifidobacteriales	201174|Actinobacteria	S	YhgE Pip domain protein	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,DUF3533
AKELHBIC_00408	216816.GS08_10280	0.0	1070.0	COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ2A@85004|Bifidobacteriales	201174|Actinobacteria	S	YhgE Pip domain protein	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
AKELHBIC_00410	445975.COLSTE_02537	1.1e-35	142.0	2AHMW@1|root,317ZU@2|Bacteria,2HC22@201174|Actinobacteria	201174|Actinobacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00411	463191.SSEG_10754	6.49e-17	80.9	2EPJ6@1|root,33H5U@2|Bacteria,2IT42@201174|Actinobacteria	201174|Actinobacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00412	445975.COLSTE_02537	1.1e-35	142.0	2AHMW@1|root,317ZU@2|Bacteria,2HC22@201174|Actinobacteria	201174|Actinobacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00413	216816.GS08_10300	6.67e-188	521.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4CYUW@85004|Bifidobacteriales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
AKELHBIC_00414	216816.GS08_10305	4.32e-297	811.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4CYW0@85004|Bifidobacteriales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	ilvA	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1559	PALP,Thr_dehydrat_C
AKELHBIC_00415	326426.Bbr_1855	0.0	1157.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CZT7@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha amylase, catalytic domain protein	-	-	3.2.1.10	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R01718,R01791,R06199	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
AKELHBIC_00416	1437603.BMON_1916	2.25e-12	68.6	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_00417	326426.Bbr_1865	7.15e-197	546.0	COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria,4D02Q@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
AKELHBIC_00418	326426.Bbr_1866	2.22e-207	575.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZPG@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
AKELHBIC_00419	326426.Bbr_1867	3.26e-312	850.0	COG1653@1|root,COG1653@2|Bacteria,2GN9T@201174|Actinobacteria,4CZ4V@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_00420	326426.Bbr_1868	1.59e-287	785.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2GMBH@201174|Actinobacteria,4CZK4@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
AKELHBIC_00421	216816.GS08_10375	0.0	1512.0	COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4CZJB@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 36 N-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
AKELHBIC_00422	326426.Bbr_1870	7.75e-106	305.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4D0V0@85004|Bifidobacteriales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
AKELHBIC_00423	216816.GS08_10385	0.0	1268.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4CZC4@85004|Bifidobacteriales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	nhaP	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
AKELHBIC_00424	216816.GS08_10390	7.51e-190	526.0	COG0400@1|root,COG0400@2|Bacteria,2I5NR@201174|Actinobacteria,4CZJQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
AKELHBIC_00425	216816.GS08_10395	3.85e-178	499.0	2BFMF@1|root,329FS@2|Bacteria,2IGC7@201174|Actinobacteria,4D0RD@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00426	216816.GS08_10400	4.97e-143	402.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4CZEB@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
AKELHBIC_00427	216816.GS08_10405	7.91e-203	582.0	2DDMI@1|root,2ZIJN@2|Bacteria,2ICIR@201174|Actinobacteria,4D00F@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR
AKELHBIC_00428	702459.BBPR_1021	2.58e-220	623.0	COG1823@1|root,COG1823@2|Bacteria,2I862@201174|Actinobacteria,4D08P@85004|Bifidobacteriales	201174|Actinobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K06956	-	-	-	-	ko00000	-	-	-	SDF
AKELHBIC_00429	1437600.JDUI01000002_gene1568	3.58e-209	595.0	COG3469@1|root,COG3525@1|root,COG3469@2|Bacteria,COG3525@2|Bacteria,2ICVB@201174|Actinobacteria,4D04M@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase, family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
AKELHBIC_00431	216816.GS08_10410	0.0	1758.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CZ1I@85004|Bifidobacteriales	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	pacL2	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
AKELHBIC_00432	1437609.BCAL_1414	4.22e-19	85.9	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZ05@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00433	326426.Bbr_1879	1.19e-107	311.0	COG2190@1|root,COG2190@2|Bacteria,2INQB@201174|Actinobacteria,4D11R@85004|Bifidobacteriales	201174|Actinobacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1	-	-	2.7.1.208	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12	-	-	PTS_EIIA_1
AKELHBIC_00434	326426.Bbr_1880	0.0	992.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,2GKPM@201174|Actinobacteria,4D069@85004|Bifidobacteriales	201174|Actinobacteria	G	phosphotransferase system, EIIB	nagE	-	2.7.1.193	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
AKELHBIC_00435	158787.BSCA_2285	2.74e-274	785.0	COG3934@1|root,COG3934@2|Bacteria,2I5AM@201174|Actinobacteria	201174|Actinobacteria	G	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
AKELHBIC_00436	158787.BSCA_0158	7.59e-61	190.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
AKELHBIC_00437	158787.BSCA_0159	4.62e-14	67.8	COG3293@1|root,COG3293@2|Bacteria,2GX1N@201174|Actinobacteria,4D2D5@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2
AKELHBIC_00438	266940.Krad_4190	9.88e-92	282.0	COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AKELHBIC_00439	266940.Krad_4189	4.9e-96	293.0	COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AKELHBIC_00440	43759.JNWK01000061_gene2644	9.63e-73	242.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_00441	1246448.ANAZ01000035_gene168	4.7e-60	203.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4EHAQ@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00442	216816.GS08_10420	0.0	881.0	COG1373@1|root,COG1373@2|Bacteria,2HJ52@201174|Actinobacteria,4D2TQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_00443	326426.Bbr_1881	3.26e-260	716.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria,4CZVY@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
AKELHBIC_00444	216816.GS08_10430	2.64e-220	609.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CZB1@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
AKELHBIC_00445	216816.GS08_10435	0.0	928.0	COG0515@1|root,COG0515@2|Bacteria,2I2F0@201174|Actinobacteria,4CZ2E@85004|Bifidobacteriales	201174|Actinobacteria	KLT	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
AKELHBIC_00446	216816.GS08_10440	1.47e-267	733.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CYU6@85004|Bifidobacteriales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	ugpC	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
AKELHBIC_00447	216816.GS08_10445	6.64e-279	763.0	COG0463@1|root,COG0463@2|Bacteria,2I2GT@201174|Actinobacteria,4CZ0W@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
AKELHBIC_00448	216816.GS08_10450	7.28e-243	666.0	COG0208@1|root,COG0208@2|Bacteria,2GK46@201174|Actinobacteria,4CYQ2@85004|Bifidobacteriales	201174|Actinobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0090304,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
AKELHBIC_00450	216816.GS08_10460	0.0	1416.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CZF3@85004|Bifidobacteriales	201174|Actinobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdE	GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0051063,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN
AKELHBIC_00451	216816.GS08_10465	2.42e-105	304.0	COG1780@1|root,COG1780@2|Bacteria,2IM4D@201174|Actinobacteria,4D0XV@85004|Bifidobacteriales	201174|Actinobacteria	F	Probably involved in ribonucleotide reductase function	nrdI	-	-	ko:K03647	-	-	-	-	ko00000	-	-	-	Flavodoxin_NdrI
AKELHBIC_00452	216816.GS08_10470	9.4e-57	176.0	COG0695@1|root,COG0695@2|Bacteria,2IRCP@201174|Actinobacteria,4D17U@85004|Bifidobacteriales	201174|Actinobacteria	O	Glutaredoxin	nrdH	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
AKELHBIC_00453	216816.GS08_10475	1.95e-140	398.0	COG1396@1|root,COG1396@2|Bacteria,2IF66@201174|Actinobacteria,4CZYD@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
AKELHBIC_00454	216816.GS08_10485	1.4e-55	179.0	COG1226@1|root,COG1226@2|Bacteria,2GKNF@201174|Actinobacteria,4CZUV@85004|Bifidobacteriales	201174|Actinobacteria	U	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
AKELHBIC_00455	216816.GS08_10490	1.02e-259	712.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4CZV8@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
AKELHBIC_00456	216816.GS08_10495	0.0	899.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4CYQG@85004|Bifidobacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
AKELHBIC_00457	216816.GS08_10500	3.73e-180	507.0	COG1651@1|root,COG1651@2|Bacteria,2GN3N@201174|Actinobacteria,4CZBD@85004|Bifidobacteriales	201174|Actinobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
AKELHBIC_00459	216816.GS08_10510	3.62e-275	763.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4CYY0@85004|Bifidobacteriales	201174|Actinobacteria	S	G5	rpfB	GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
AKELHBIC_00460	216816.GS08_10515	1.3e-211	585.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CYS9@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
AKELHBIC_00461	216816.GS08_10520	2.19e-221	611.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4CZMW@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
AKELHBIC_00462	216816.GS08_10525	3.99e-141	399.0	2E1BJ@1|root,32WRF@2|Bacteria,2IKG0@201174|Actinobacteria,4D0S1@85004|Bifidobacteriales	201174|Actinobacteria	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
AKELHBIC_00463	216816.GS08_10530	0.0	947.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4CYUH@85004|Bifidobacteriales	201174|Actinobacteria	J	Probable RNA and SrmB- binding site of polymerase A	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
AKELHBIC_00464	216816.GS08_10535	8.3e-247	684.0	COG0494@1|root,COG0494@2|Bacteria,2GWEB@201174|Actinobacteria,4CZAV@85004|Bifidobacteriales	201174|Actinobacteria	L	Belongs to the Nudix hydrolase family	mutT4	-	-	-	-	-	-	-	-	-	-	-	NUDIX
AKELHBIC_00465	216816.GS08_10540	0.0	1276.0	2CETP@1|root,33P5Y@2|Bacteria,2GMJ0@201174|Actinobacteria,4CZCV@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00466	326426.Bbr_1917	0.0	1444.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CZ8M@85004|Bifidobacteriales	201174|Actinobacteria	KLT	MviN-like protein	mviN	GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
AKELHBIC_00467	216816.GS08_10550	1.79e-13	68.9	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CZ8M@85004|Bifidobacteriales	201174|Actinobacteria	KLT	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
AKELHBIC_00468	216816.GS08_10555	3.04e-235	648.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CYU9@85004|Bifidobacteriales	201174|Actinobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
AKELHBIC_00469	216816.GS08_10560	2.76e-291	799.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4CYUE@85004|Bifidobacteriales	201174|Actinobacteria	K	Belongs to the ParB family	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
AKELHBIC_00470	216816.GS08_10565	1.49e-227	627.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CZ2D@85004|Bifidobacteriales	201174|Actinobacteria	D	CobQ CobB MinD ParA nucleotide binding domain protein	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
AKELHBIC_00471	216816.GS08_10570	2.41e-157	441.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4CZ29@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
AKELHBIC_00472	216816.GS08_10575	4.48e-120	343.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4CYQQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative single-stranded nucleic acids-binding domain	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
AKELHBIC_00473	216816.GS08_10580	1.04e-224	621.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CYZ2@85004|Bifidobacteriales	201174|Actinobacteria	U	Membrane protein insertase, YidC Oxa1 family	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
AKELHBIC_00474	1122228.AQXR01000009_gene1328	3.25e-20	80.9	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4D1EF@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
AKELHBIC_00475	216816.GS08_00005	0.0	979.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CZDW@85004|Bifidobacteriales	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
AKELHBIC_00476	216816.GS08_00010	2.52e-263	722.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CZTV@85004|Bifidobacteriales	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
AKELHBIC_00477	216816.GS08_00015	2.35e-285	781.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CZQT@85004|Bifidobacteriales	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
AKELHBIC_00478	216816.GS08_00020	2.31e-105	304.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4D157@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
AKELHBIC_00479	216816.GS08_00025	0.0	1371.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CZ47@85004|Bifidobacteriales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
AKELHBIC_00480	216816.GS08_00030	0.0	1698.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CYRP@85004|Bifidobacteriales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
AKELHBIC_00481	216816.GS08_00035	1.08e-105	308.0	COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria,4D0XB@85004|Bifidobacteriales	201174|Actinobacteria	S	Transmembrane domain of unknown function (DUF3566)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3566
AKELHBIC_00482	216816.GS08_00040	0.0	942.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4CZTD@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
AKELHBIC_00483	1437610.BREU_1933	8.36e-18	83.2	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4D04H@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00484	326426.Bbr_0012	9.28e-317	863.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4CYTN@85004|Bifidobacteriales	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
AKELHBIC_00485	158787.BSCA_0146	1.82e-142	428.0	COG1409@1|root,COG2365@1|root,COG1409@2|Bacteria,COG2365@2|Bacteria	2|Bacteria	T	protein tyrosine phosphatase activity	cpdA	-	2.1.2.2,3.1.3.48,3.1.4.17,3.1.4.53	ko:K01104,ko:K01120,ko:K03651,ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,ko02025,map00230,map00670,map01100,map01110,map01130,map02025	M00048	R00191,R01234,R04325,R04326	RC00026,RC00197,RC00296,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Metallophos,Y_phosphatase3
AKELHBIC_00486	158787.BSCA_0147	4.65e-127	377.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CZPE@85004|Bifidobacteriales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
AKELHBIC_00487	158787.BSCA_0148	1.83e-243	686.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
AKELHBIC_00488	158787.BSCA_0149	1.27e-165	473.0	COG1840@1|root,COG1840@2|Bacteria,2I8D6@201174|Actinobacteria	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
AKELHBIC_00489	158787.BSCA_0150	1.24e-86	266.0	COG1737@1|root,COG1737@2|Bacteria,2HY2W@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator, rpir family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
AKELHBIC_00490	411471.SUBVAR_05571	6.73e-38	129.0	COG3041@1|root,COG3041@2|Bacteria,1VENE@1239|Firmicutes,24MW1@186801|Clostridia,3WJV4@541000|Ruminococcaceae	186801|Clostridia	S	addiction module toxin, RelE StbE family	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
AKELHBIC_00491	1050201.KB913034_gene1271	3.58e-38	129.0	COG3077@1|root,COG3077@2|Bacteria,1VABY@1239|Firmicutes,3VS2P@526524|Erysipelotrichia	526524|Erysipelotrichia	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
AKELHBIC_00492	702459.BBPR_0068	1.37e-56	191.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_00493	1437608.BBIA_0506	2.6e-28	115.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	tnpA	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_00494	356829.BITS_1714	1.49e-48	165.0	292A9@1|root,2ZPUU@2|Bacteria,2GSI5@201174|Actinobacteria,4D2CQ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00496	1688.BCUN_2047	3.21e-17	84.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
AKELHBIC_00499	1158608.I583_02319	8.64e-74	243.0	COG0737@1|root,COG0737@2|Bacteria,1TVGD@1239|Firmicutes,4I2HX@91061|Bacilli,4AZS9@81852|Enterococcaceae	91061|Bacilli	F	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
AKELHBIC_00500	1158608.I583_02320	1.17e-104	311.0	COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,4HBI5@91061|Bacilli,4B6VX@81852|Enterococcaceae	91061|Bacilli	U	Binding-protein-dependent transport system inner membrane component	ptxC	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
AKELHBIC_00501	1158609.I586_02120	7.25e-101	301.0	COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,4HBT8@91061|Bacilli,4B0SX@81852|Enterococcaceae	91061|Bacilli	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
AKELHBIC_00502	1158608.I583_02322	1.7e-104	310.0	COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,4HC3N@91061|Bacilli,4B1GW@81852|Enterococcaceae	91061|Bacilli	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
AKELHBIC_00503	1158608.I583_02323	2.87e-145	418.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,4B0DG@81852|Enterococcaceae	91061|Bacilli	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
AKELHBIC_00504	1123065.ATWL01000002_gene1504	1.12e-24	107.0	COG1737@1|root,COG1737@2|Bacteria,2HY2W@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator, rpir family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
AKELHBIC_00505	443906.CMM_2194	2.63e-34	130.0	COG1011@1|root,COG1011@2|Bacteria,2I53Y@201174|Actinobacteria,4FTPD@85023|Microbacteriaceae	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
AKELHBIC_00506	762211.BSTEL_1913	8.71e-257	710.0	COG1373@1|root,COG1373@2|Bacteria,2ICQ6@201174|Actinobacteria,4D04Z@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_00507	216816.GS08_00110	2.49e-187	521.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4CZF9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
AKELHBIC_00508	1437608.BBIA_2393	1.16e-43	149.0	COG2186@1|root,COG2186@2|Bacteria,2GKBM@201174|Actinobacteria,4CYZS@85004|Bifidobacteriales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
AKELHBIC_00510	216816.GS08_00120	0.0	871.0	COG1373@1|root,COG1373@2|Bacteria,2GM3Y@201174|Actinobacteria,4D05H@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_00511	326426.Bbr_0016	7.7e-110	316.0	COG0783@1|root,COG0783@2|Bacteria,2IFDP@201174|Actinobacteria,4CZV3@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
AKELHBIC_00512	326426.Bbr_0035	3.36e-305	834.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CZKA@85004|Bifidobacteriales	201174|Actinobacteria	P	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
AKELHBIC_00513	326426.Bbr_0036	1.5e-257	707.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4CZV8@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
AKELHBIC_00514	762211.BSTEL_0971	1.66e-86	273.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2GKEU@201174|Actinobacteria,4D1IQ@85004|Bifidobacteriales	201174|Actinobacteria	V	Forkhead associated domain	-	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K01990,ko:K21397	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA,Yop-YscD_cpl
AKELHBIC_00515	216816.GS08_00145	7.4e-155	435.0	COG0288@1|root,COG0288@2|Bacteria,2GT5H@201174|Actinobacteria,4D06V@85004|Bifidobacteriales	201174|Actinobacteria	P	Reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
AKELHBIC_00516	216816.GS08_00150	9.71e-138	389.0	COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria,4CZXS@85004|Bifidobacteriales	201174|Actinobacteria	O	C-terminal domain of 1-Cys peroxiredoxin	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
AKELHBIC_00517	216816.GS08_00155	0.0	1154.0	COG0492@1|root,COG3634@1|root,COG0492@2|Bacteria,COG3634@2|Bacteria,2GKD2@201174|Actinobacteria,4CZ6G@85004|Bifidobacteriales	201174|Actinobacteria	C	Thioredoxin domain	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
AKELHBIC_00518	216816.GS08_00160	6.52e-307	837.0	COG0477@1|root,COG2814@2|Bacteria,2I2ID@201174|Actinobacteria,4CZX9@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
AKELHBIC_00519	1437610.BREU_1930	2.32e-53	171.0	COG1373@1|root,COG1373@2|Bacteria,2GK4E@201174|Actinobacteria,4CZX6@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_00520	78344.BIGA_1786	1.21e-52	167.0	COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
AKELHBIC_00521	216816.GS08_09870	6.38e-259	709.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria,4D2KU@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
AKELHBIC_00522	216816.GS08_03825	5.55e-247	676.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria,4D2Q1@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
AKELHBIC_00523	216816.GS08_02215	3.49e-290	792.0	COG0582@1|root,COG0582@2|Bacteria,2HB7R@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
AKELHBIC_00524	1437610.BREU_1897	7.81e-214	599.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_2
AKELHBIC_00525	78346.BRUM_0133	1.43e-250	692.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00526	326426.Bbr_0626	0.0	1025.0	COG1215@1|root,COG1215@2|Bacteria,2GN8M@201174|Actinobacteria,4D042@85004|Bifidobacteriales	201174|Actinobacteria	M	probably involved in cell wall	-	-	-	-	-	-	-	-	-	-	-	-	EAL,Glyco_trans_2_3
AKELHBIC_00527	547043.BIFPSEUDO_04293	1.22e-37	135.0	COG1609@1|root,COG1609@2|Bacteria,2GJDS@201174|Actinobacteria,4CZR6@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00528	547043.BIFPSEUDO_04293	1.61e-168	476.0	COG1609@1|root,COG1609@2|Bacteria,2GJDS@201174|Actinobacteria,4CZR6@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00529	547043.BIFPSEUDO_04291	0.0	880.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4CYX5@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_00530	547043.BIFPSEUDO_04290	4.73e-214	592.0	COG1175@1|root,COG1175@2|Bacteria,2GJZD@201174|Actinobacteria,4CYTH@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
AKELHBIC_00531	547043.BIFPSEUDO_04289	4.43e-193	537.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4CYRC@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10119	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
AKELHBIC_00532	566552.BIFCAT_00237	1.88e-290	796.0	COG1215@1|root,COG4030@1|root,COG1215@2|Bacteria,COG4030@2|Bacteria,2GJFD@201174|Actinobacteria,4CZ06@85004|Bifidobacteriales	201174|Actinobacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
AKELHBIC_00533	547043.BIFPSEUDO_04286	1.51e-159	449.0	COG0657@1|root,COG0657@2|Bacteria,2HZCA@201174|Actinobacteria,4CZQE@85004|Bifidobacteriales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
AKELHBIC_00534	1437610.BREU_1897	6.5e-30	115.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_2
AKELHBIC_00535	326426.Bbr_0356	5.4e-293	800.0	COG1373@1|root,COG1373@2|Bacteria,2I96U@201174|Actinobacteria,4CZD7@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_00536	216816.GS08_00175	0.0	1065.0	COG1414@1|root,COG2865@1|root,COG1414@2|Bacteria,COG2865@2|Bacteria,2I3IG@201174|Actinobacteria,4CZRW@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,MarR_2
AKELHBIC_00537	216816.GS08_00180	1.95e-45	146.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4CZS0@85004|Bifidobacteriales	201174|Actinobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
AKELHBIC_00538	566552.BIFCAT_00537	0.0	1257.0	COG3409@1|root,COG3409@2|Bacteria,2GMEN@201174|Actinobacteria,4D0FU@85004|Bifidobacteriales	201174|Actinobacteria	M	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,PG_binding_1
AKELHBIC_00539	78345.BMERY_0419	1.58e-12	69.7	2A2J6@1|root,30QX2@2|Bacteria,2H59P@201174|Actinobacteria,4D29B@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00540	86416.Clopa_1034	1.34e-237	673.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,36EUU@31979|Clostridiaceae	186801|Clostridia	E	family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
AKELHBIC_00541	1195236.CTER_2894	1.64e-157	449.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
AKELHBIC_00542	272562.CA_C3181	1.73e-121	357.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N,RCC1_2
AKELHBIC_00543	864069.MicloDRAFT_00031430	1e-185	545.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,1JSFR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K13892	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	ABC_tran,oligo_HPY
AKELHBIC_00544	216816.GS08_00195	8.61e-50	166.0	COG3409@1|root,COG3409@2|Bacteria,2GMEN@201174|Actinobacteria,4D1HF@85004|Bifidobacteriales	201174|Actinobacteria	M	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,PG_binding_1
AKELHBIC_00546	216816.GS08_00205	0.0	1819.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4CZS0@85004|Bifidobacteriales	201174|Actinobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
AKELHBIC_00547	216816.GS08_00210	0.0	1226.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,2HZ8C@201174|Actinobacteria,4CYR2@85004|Bifidobacteriales	201174|Actinobacteria	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
AKELHBIC_00548	345341.KUTG_01732	1e-57	204.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
AKELHBIC_00549	1120959.ATXF01000011_gene203	2.07e-14	75.9	COG0640@1|root,COG0640@2|Bacteria,2II9U@201174|Actinobacteria,4FPUJ@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
AKELHBIC_00550	518635.BIFANG_03609	8.25e-121	364.0	COG0477@1|root,COG2814@2|Bacteria,2I8QF@201174|Actinobacteria,4CZF1@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
AKELHBIC_00551	216816.GS08_00215	0.0	948.0	COG0591@1|root,COG0591@2|Bacteria,2I041@201174|Actinobacteria,4CZS2@85004|Bifidobacteriales	201174|Actinobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
AKELHBIC_00552	1437608.BBIA_2535	8.11e-72	221.0	COG5340@1|root,COG5340@2|Bacteria,2IMTJ@201174|Actinobacteria,4D150@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00553	1437608.BBIA_2536	6.39e-136	394.0	COG2253@1|root,COG2253@2|Bacteria,2IHDQ@201174|Actinobacteria,4D0UC@85004|Bifidobacteriales	201174|Actinobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
AKELHBIC_00554	216816.GS08_00230	9.83e-260	712.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4CYXM@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
AKELHBIC_00555	326426.Bbr_0058	4.19e-58	182.0	2EGRW@1|root,32FNP@2|Bacteria,2HZNH@201174|Actinobacteria,4D120@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3073)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3073
AKELHBIC_00556	216816.GS08_00240	2.3e-139	395.0	COG2197@1|root,COG2197@2|Bacteria,2IF55@201174|Actinobacteria,4D0XW@85004|Bifidobacteriales	201174|Actinobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
AKELHBIC_00557	216816.GS08_00245	1.36e-267	733.0	COG4585@1|root,COG4585@2|Bacteria,2IC0A@201174|Actinobacteria,4D04K@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00558	216816.GS08_00250	3.83e-311	850.0	COG0477@1|root,COG0477@2|Bacteria,2I3AP@201174|Actinobacteria,4D0YC@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_00559	216816.GS08_00255	7.77e-98	284.0	COG3255@1|root,COG3255@2|Bacteria,2IQBF@201174|Actinobacteria,4D10H@85004|Bifidobacteriales	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
AKELHBIC_00560	216816.GS08_00260	0.0	1632.0	COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4CZ3V@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
AKELHBIC_00561	216816.GS08_00265	2.06e-46	149.0	2BFAJ@1|root,3293I@2|Bacteria,2ISGB@201174|Actinobacteria,4D185@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00562	216816.GS08_00270	2.37e-162	455.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4CZJ0@85004|Bifidobacteriales	201174|Actinobacteria	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
AKELHBIC_00563	216816.GS08_00275	2.89e-104	301.0	2E4NY@1|root,32ZHR@2|Bacteria,2GQPW@201174|Actinobacteria,4D0ZH@85004|Bifidobacteriales	201174|Actinobacteria	D	Involved in cell division	crgA	-	-	-	-	-	-	-	-	-	-	-	CrgA
AKELHBIC_00564	216816.GS08_00280	9.04e-154	436.0	COG3879@1|root,COG3879@2|Bacteria,2GJ9Y@201174|Actinobacteria,4CZ1A@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
AKELHBIC_00565	216816.GS08_00285	9.08e-299	815.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4CYZ5@85004|Bifidobacteriales	201174|Actinobacteria	M	Sortase family	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
AKELHBIC_00566	216816.GS08_00290	3.18e-154	432.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4D09E@85004|Bifidobacteriales	201174|Actinobacteria	EH	para-aminobenzoate synthase glutamine amidotransferase component II	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
AKELHBIC_00567	216816.GS08_00295	0.0	1179.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CZFU@85004|Bifidobacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
AKELHBIC_00568	216816.GS08_00300	2.56e-220	608.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4CYUK@85004|Bifidobacteriales	201174|Actinobacteria	T	Protein tyrosine kinase	pknA	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
AKELHBIC_00569	216816.GS08_00305	0.0	911.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4CYTI@85004|Bifidobacteriales	201174|Actinobacteria	M	penicillin-binding protein	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
AKELHBIC_00570	216816.GS08_00310	0.0	908.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CZ67@85004|Bifidobacteriales	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
AKELHBIC_00571	216816.GS08_00315	0.0	924.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CZDN@85004|Bifidobacteriales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
AKELHBIC_00572	1437610.BREU_0878	3.15e-85	255.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4D0RN@85004|Bifidobacteriales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
AKELHBIC_00573	216816.GS08_00325	6.12e-166	464.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CYUI@85004|Bifidobacteriales	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
AKELHBIC_00574	216816.GS08_00330	0.0	1509.0	COG1506@1|root,COG1506@2|Bacteria,2GJ6A@201174|Actinobacteria,4CZAE@85004|Bifidobacteriales	201174|Actinobacteria	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	pepX	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
AKELHBIC_00575	216816.GS08_00335	3.86e-263	720.0	COG2267@1|root,COG2267@2|Bacteria,2HZ9U@201174|Actinobacteria,4CZ5E@85004|Bifidobacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	pldB	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
AKELHBIC_00576	216816.GS08_00365	1.21e-187	526.0	COG0697@1|root,COG0697@2|Bacteria,2GM6M@201174|Actinobacteria,4CZPP@85004|Bifidobacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
AKELHBIC_00577	216816.GS08_00375	9.78e-291	801.0	COG0627@1|root,COG0627@2|Bacteria,2GP6Q@201174|Actinobacteria,4CYXF@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
AKELHBIC_00578	216816.GS08_00380	0.0	1664.0	COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria,4CYW5@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	lysX	-	-	-	-	-	-	-	-	-	-	-	DUF2156,Rhomboid
AKELHBIC_00579	216816.GS08_00385	8.45e-237	650.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,2GJ1S@201174|Actinobacteria,4CZXJ@85004|Bifidobacteriales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0016491,GO:0016667,GO:0016671,GO:0020012,GO:0030682,GO:0033744,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0075136	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
AKELHBIC_00580	216816.GS08_00390	9.21e-142	400.0	COG3467@1|root,COG3467@2|Bacteria,2IGUA@201174|Actinobacteria,4D0SF@85004|Bifidobacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
AKELHBIC_00581	216816.GS08_00395	7.56e-209	577.0	COG1215@1|root,COG1215@2|Bacteria,2I2IF@201174|Actinobacteria,4CYW6@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
AKELHBIC_00582	326426.Bbr_0085	0.0	2130.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,2GJ4Y@201174|Actinobacteria,4CZNN@85004|Bifidobacteriales	201174|Actinobacteria	KL	Domain of unknown function (DUF3427)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
AKELHBIC_00583	216816.GS08_00405	9.5e-98	283.0	COG0494@1|root,COG0494@2|Bacteria,2I2GY@201174|Actinobacteria,4D0UJ@85004|Bifidobacteriales	201174|Actinobacteria	L	NUDIX domain	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
AKELHBIC_00584	216816.GS08_00410	1.23e-69	210.0	COG0393@1|root,COG0393@2|Bacteria,2IQNY@201174|Actinobacteria,4D0ZM@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
AKELHBIC_00585	216816.GS08_00415	7.45e-109	314.0	COG2153@1|root,COG2153@2|Bacteria,2HZKP@201174|Actinobacteria,4D0UN@85004|Bifidobacteriales	201174|Actinobacteria	Q	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
AKELHBIC_00586	326426.Bbr_0087	5.92e-168	473.0	COG1272@1|root,COG1272@2|Bacteria,2HRAC@201174|Actinobacteria,4D0D6@85004|Bifidobacteriales	201174|Actinobacteria	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
AKELHBIC_00587	1680.BADO_0041	1.69e-92	271.0	COG0071@1|root,COG0071@2|Bacteria,2HZHR@201174|Actinobacteria,4D0H9@85004|Bifidobacteriales	201174|Actinobacteria	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
AKELHBIC_00588	1211817.CCAT010000062_gene3991	5.49e-72	224.0	COG0693@1|root,COG0693@2|Bacteria,1TPJK@1239|Firmicutes,24BTV@186801|Clostridia,36DI2@31979|Clostridiaceae	186801|Clostridia	S	PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
AKELHBIC_00590	1408311.JNJM01000016_gene3494	9.53e-29	112.0	2BZT8@1|root,32W5F@2|Bacteria,1UGQC@1239|Firmicutes,24Q23@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
AKELHBIC_00593	216816.GS08_00435	0.0	889.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,4CZNX@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
AKELHBIC_00594	216816.GS08_00440	0.0	978.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CZAP@85004|Bifidobacteriales	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	degP	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
AKELHBIC_00595	216816.GS08_00445	0.0	1165.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ4F@85004|Bifidobacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
AKELHBIC_00596	158787.BSCA_0636	3.07e-244	679.0	COG0683@1|root,COG0683@2|Bacteria,2I8ME@201174|Actinobacteria,4D087@85004|Bifidobacteriales	201174|Actinobacteria	E	Receptor family ligand binding region	urtA	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
AKELHBIC_00597	1437609.BCAL_2279	6.46e-164	464.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4D0FD@85004|Bifidobacteriales	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	urtB	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
AKELHBIC_00598	1437609.BCAL_2280	1.1e-202	568.0	COG4177@1|root,COG4177@2|Bacteria,2GNZK@201174|Actinobacteria,4CZJ2@85004|Bifidobacteriales	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	urtC	-	-	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
AKELHBIC_00599	158787.BSCA_0633	4.04e-147	422.0	COG4674@1|root,COG4674@2|Bacteria,2GP3Y@201174|Actinobacteria,4D03S@85004|Bifidobacteriales	201174|Actinobacteria	S	Branched-chain amino acid ATP-binding cassette transporter	urtD	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
AKELHBIC_00600	1437609.BCAL_2282	2.05e-128	369.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4D0EB@85004|Bifidobacteriales	201174|Actinobacteria	E	ABC transporter	urtE	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
AKELHBIC_00601	1444306.JFZC01000038_gene2861	1.87e-138	403.0	COG2042@1|root,COG3376@2|Bacteria,1TSSI@1239|Firmicutes,4HEUV@91061|Bacilli	91061|Bacilli	U	Belongs to the NiCoT transporter (TC 2.A.52) family	hoxN	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
AKELHBIC_00602	158787.BSCA_0625	6.14e-123	355.0	COG0831@1|root,COG0832@1|root,COG0831@2|Bacteria,COG0832@2|Bacteria,2IKNA@201174|Actinobacteria,4CZA2@85004|Bifidobacteriales	201174|Actinobacteria	E	Urease, gamma subunit	ureA	-	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
AKELHBIC_00603	1437608.BBIA_0134	0.0	1053.0	COG0804@1|root,COG0804@2|Bacteria,2GM7X@201174|Actinobacteria,4D0G9@85004|Bifidobacteriales	201174|Actinobacteria	E	Urease alpha-subunit, N-terminal domain	ureC	-	3.5.1.5	ko:K01427,ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
AKELHBIC_00604	1437609.BCAL_2304	5.83e-114	330.0	COG2371@1|root,COG2371@2|Bacteria,2IDSE@201174|Actinobacteria,4D05Y@85004|Bifidobacteriales	201174|Actinobacteria	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C
AKELHBIC_00605	1437609.BCAL_2303	2.61e-100	301.0	COG0830@1|root,COG0830@2|Bacteria,2HZCE@201174|Actinobacteria,4CZRB@85004|Bifidobacteriales	201174|Actinobacteria	J	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
AKELHBIC_00606	1437609.BCAL_2302	2.59e-127	363.0	COG0378@1|root,COG0378@2|Bacteria,2GNUV@201174|Actinobacteria,4D0FK@85004|Bifidobacteriales	201174|Actinobacteria	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
AKELHBIC_00607	1437609.BCAL_2301	1.98e-113	335.0	COG0829@1|root,COG0829@2|Bacteria,2HZI9@201174|Actinobacteria,4D0IT@85004|Bifidobacteriales	201174|Actinobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
AKELHBIC_00608	398513.BBNG_01395	2.72e-121	360.0	COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales	201174|Actinobacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
AKELHBIC_00609	398513.BBNG_01398	2.1e-262	735.0	COG4932@1|root,COG4932@2|Bacteria,2IMAM@201174|Actinobacteria,4D2UC@85004|Bifidobacteriales	201174|Actinobacteria	M	LPXTG cell wall anchor motif	-	-	-	-	-	-	-	-	-	-	-	-	GramPos_pilinBB,Gram_pos_anchor
AKELHBIC_00610	566552.BIFCAT_00266	6.61e-19	84.3	2AWBM@1|root,31N7D@2|Bacteria,2IP6P@201174|Actinobacteria,4D14B@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00611	216816.GS08_00455	0.0	943.0	COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,4CZIT@85004|Bifidobacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	fprA	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
AKELHBIC_00612	216816.GS08_00460	1.18e-205	571.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CYVY@85004|Bifidobacteriales	201174|Actinobacteria	O	Belongs to the peptidase M48B family	htpX	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
AKELHBIC_00614	326426.Bbr_0312	4.77e-274	754.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D01G@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00615	742742.HMPREF9452_02057	2.47e-124	409.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.2.1.4	ko:K01179,ko:K21449	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	1.B.40.2	GH5,GH9	-	DUF1929,Laminin_G_3,Metallophos
AKELHBIC_00617	216816.GS08_00470	6.67e-263	722.0	COG0477@1|root,COG2814@2|Bacteria,2HZWA@201174|Actinobacteria,4D211@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_00619	216816.GS08_00475	1.72e-153	432.0	COG3663@1|root,COG3663@2|Bacteria,2GNS5@201174|Actinobacteria,4D132@85004|Bifidobacteriales	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
AKELHBIC_00620	216816.GS08_00480	1.15e-262	719.0	COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,4CZJI@85004|Bifidobacteriales	201174|Actinobacteria	G	Fructose-bisphosphate aldolase class-II	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
AKELHBIC_00621	1123075.AUDP01000030_gene1808	3.23e-45	163.0	COG3950@1|root,COG3950@2|Bacteria,1TQIC@1239|Firmicutes,24EDD@186801|Clostridia,3WKZ3@541000|Ruminococcaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
AKELHBIC_00622	216816.GS08_00500	0.0	864.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CZ0U@85004|Bifidobacteriales	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
AKELHBIC_00623	216816.GS08_00505	0.0	977.0	COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,2GPPN@201174|Actinobacteria,4CZQR@85004|Bifidobacteriales	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	TrkA_C,Voltage_CLC
AKELHBIC_00624	326426.Bbr_0097	2.48e-198	556.0	COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D0RK@85004|Bifidobacteriales	201174|Actinobacteria	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
AKELHBIC_00625	547043.BIFPSEUDO_04070	1.88e-83	247.0	COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D14T@85004|Bifidobacteriales	201174|Actinobacteria	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
AKELHBIC_00626	216816.GS08_00545	1.15e-257	706.0	COG1609@1|root,COG1609@2|Bacteria,2GMHV@201174|Actinobacteria,4CZ3G@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
AKELHBIC_00627	216816.GS08_00550	0.0	1022.0	COG0366@1|root,COG0366@2|Bacteria,2GNEC@201174|Actinobacteria,4CZ4T@85004|Bifidobacteriales	201174|Actinobacteria	G	Domain of unknown function (DUF1964)	gtfA	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF1964
AKELHBIC_00628	216816.GS08_00555	0.0	1020.0	COG2211@1|root,COG2211@2|Bacteria,2GJZG@201174|Actinobacteria,4CZ93@85004|Bifidobacteriales	201174|Actinobacteria	G	Transporter major facilitator family protein	scrT	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2
AKELHBIC_00629	216816.GS08_00560	0.0	890.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4CYY8@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
AKELHBIC_00630	216816.GS08_00565	8.38e-259	708.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CZBR@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
AKELHBIC_00631	327277.JHAL01000002_gene48	5.46e-66	208.0	COG0619@1|root,COG0619@2|Bacteria,2IQMQ@201174|Actinobacteria,4D23J@85004|Bifidobacteriales	201174|Actinobacteria	P	Cobalt transport protein	bioN	-	-	ko:K16783	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25.1	-	-	CbiQ
AKELHBIC_00632	327277.JHAL01000002_gene49	4.04e-91	275.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4D23W@85004|Bifidobacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	bioM	-	-	ko:K16784	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25.1	-	-	ABC_tran
AKELHBIC_00633	218140.BPSY_0937	2.7e-75	231.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4D0BB@85004|Bifidobacteriales	201174|Actinobacteria	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
AKELHBIC_00634	216816.GS08_00570	1.02e-259	711.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CZBR@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
AKELHBIC_00635	216816.GS08_00575	6.4e-187	519.0	28JTN@1|root,2Z9IV@2|Bacteria,2IH1U@201174|Actinobacteria,4D20Y@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00636	216816.GS08_00580	1.36e-244	672.0	COG1846@1|root,COG1846@2|Bacteria,2IR8X@201174|Actinobacteria,4D23Q@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00637	216816.GS08_00585	0.0	1260.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CZ1E@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha-amylase domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
AKELHBIC_00638	216816.GS08_00590	1.99e-238	656.0	COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4CZ1Y@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00639	1437610.BREU_0342	0.0	1465.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CZ0F@85004|Bifidobacteriales	201174|Actinobacteria	G	4-alpha-glucanotransferase	malQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
AKELHBIC_00640	1680.BADO_1460	0.0	1095.0	COG1785@1|root,COG1785@2|Bacteria,2GM8A@201174|Actinobacteria,4CYZF@85004|Bifidobacteriales	201174|Actinobacteria	P	Alkaline phosphatase homologues	strK	-	3.1.3.1,3.1.3.39	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	M00126	R02135,R02228,R04620	RC00017,RC00078	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
AKELHBIC_00641	216816.GS08_00660	0.0	1130.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CZDX@85004|Bifidobacteriales	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
AKELHBIC_00642	326426.Bbr_0125	5.65e-90	271.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4CZJ6@85004|Bifidobacteriales	201174|Actinobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
AKELHBIC_00643	216816.GS08_00670	3.79e-231	637.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CZ68@85004|Bifidobacteriales	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
AKELHBIC_00644	326426.Bbr_0127	5.09e-128	365.0	COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria,4D0Q7@85004|Bifidobacteriales	201174|Actinobacteria	K	transcriptional regulator, MerR family	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
AKELHBIC_00645	1437610.BREU_1929	1.43e-270	748.0	COG2233@1|root,COG2233@2|Bacteria,2GV9H@201174|Actinobacteria,4CZYX@85004|Bifidobacteriales	201174|Actinobacteria	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
AKELHBIC_00646	1437610.BREU_1928	1.02e-261	718.0	COG1541@1|root,COG1541@2|Bacteria,2HZHX@201174|Actinobacteria,4D0HV@85004|Bifidobacteriales	201174|Actinobacteria	H	long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
AKELHBIC_00647	1437610.BREU_1927	2.88e-292	806.0	COG1012@1|root,COG1012@2|Bacteria,2HZAQ@201174|Actinobacteria,4CZDA@85004|Bifidobacteriales	201174|Actinobacteria	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
AKELHBIC_00648	326426.Bbr_0129	1.31e-180	503.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4D0FH@85004|Bifidobacteriales	201174|Actinobacteria	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
AKELHBIC_00649	216816.GS08_00680	2.41e-158	444.0	COG0637@1|root,COG0637@2|Bacteria,2GJNG@201174|Actinobacteria,4CYZV@85004|Bifidobacteriales	201174|Actinobacteria	S	HAD hydrolase, family IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
AKELHBIC_00650	216816.GS08_00710	2.59e-171	478.0	COG0586@1|root,COG0586@2|Bacteria,2GKGR@201174|Actinobacteria,4CZ7Y@85004|Bifidobacteriales	201174|Actinobacteria	S	SNARE associated Golgi protein	dedA1	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
AKELHBIC_00651	216816.GS08_00720	5.15e-161	455.0	COG0455@1|root,COG0455@2|Bacteria,2HZIH@201174|Actinobacteria,4D0JG@85004|Bifidobacteriales	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	ParA
AKELHBIC_00652	216816.GS08_00725	5.32e-244	671.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4CZF2@85004|Bifidobacteriales	201174|Actinobacteria	U	Type II IV secretion system protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
AKELHBIC_00653	216816.GS08_00730	2.54e-137	390.0	COG4965@1|root,COG4965@2|Bacteria,2GRXU@201174|Actinobacteria,4D1A3@85004|Bifidobacteriales	201174|Actinobacteria	U	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	-
AKELHBIC_00654	216816.GS08_00735	5.47e-130	370.0	COG2064@1|root,COG2064@2|Bacteria,2I2FP@201174|Actinobacteria,4D16W@85004|Bifidobacteriales	201174|Actinobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
AKELHBIC_00655	216816.GS08_00740	3.54e-53	167.0	2EHCF@1|root,33B4A@2|Bacteria,2GR72@201174|Actinobacteria,4D1FR@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4244)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4244
AKELHBIC_00656	216816.GS08_00750	4.43e-70	212.0	2DRBM@1|root,33B4F@2|Bacteria,2HZRZ@201174|Actinobacteria,4D1G6@85004|Bifidobacteriales	201174|Actinobacteria	S	TIGRFAM helicase secretion neighborhood TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad
AKELHBIC_00657	216816.GS08_00755	7.36e-273	746.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4CZ1S@85004|Bifidobacteriales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain protein	-	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
AKELHBIC_00658	216816.GS08_00760	9.91e-137	387.0	COG1309@1|root,COG1309@2|Bacteria,2GND5@201174|Actinobacteria,4CZUU@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
AKELHBIC_00659	216816.GS08_00765	0.0	1439.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CZMY@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA polymerase III subunit gamma tau	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
AKELHBIC_00660	216816.GS08_00770	8.17e-141	397.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CZRI@85004|Bifidobacteriales	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
AKELHBIC_00661	216816.GS08_00775	1.22e-253	697.0	COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales	201174|Actinobacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
AKELHBIC_00663	326426.Bbr_0147	5.55e-168	471.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CYSD@85004|Bifidobacteriales	201174|Actinobacteria	E	Amino acid kinase family	ask	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
AKELHBIC_00664	216816.GS08_00785	1.17e-125	358.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4D00P@85004|Bifidobacteriales	201174|Actinobacteria	E	ACT domain	ask	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
AKELHBIC_00665	326426.Bbr_0149	1.03e-266	729.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4CZPY@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3708c	Semialdhyde_dh,Semialdhyde_dhC
AKELHBIC_00666	216816.GS08_00795	4.19e-146	411.0	2C7PT@1|root,2ZXN2@2|Bacteria,2GM64@201174|Actinobacteria,4CYPY@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00667	216816.GS08_00800	0.0	1056.0	COG1409@1|root,COG1409@2|Bacteria,2GNKK@201174|Actinobacteria,4CZMC@85004|Bifidobacteriales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
AKELHBIC_00668	326426.Bbr_0175	0.0	1248.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CZYW@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
AKELHBIC_00669	216816.GS08_00810	0.0	1228.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CZQZ@85004|Bifidobacteriales	201174|Actinobacteria	M	Transglycosylase	pbp5	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
AKELHBIC_00670	216816.GS08_00815	2.57e-212	591.0	COG0671@1|root,COG0671@2|Bacteria,2HIXE@201174|Actinobacteria,4CYS6@85004|Bifidobacteriales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
AKELHBIC_00671	216816.GS08_00820	0.0	1863.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4CZ85@85004|Bifidobacteriales	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
AKELHBIC_00672	216816.GS08_00825	6.05e-157	441.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4CYQ8@85004|Bifidobacteriales	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3,Thymidylate_kin
AKELHBIC_00673	326426.Bbr_0180	6.63e-259	711.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4CZ4Y@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA polymerase III	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
AKELHBIC_00674	326426.Bbr_0181	1.6e-131	375.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZ05@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00675	326426.Bbr_0182	1.47e-50	160.0	COG1925@1|root,COG1925@2|Bacteria,2GQX6@201174|Actinobacteria,4D19B@85004|Bifidobacteriales	201174|Actinobacteria	G	PTS HPr component phosphorylation site	hpr	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
AKELHBIC_00677	326426.Bbr_0183	0.0	1024.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CZ52@85004|Bifidobacteriales	201174|Actinobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
AKELHBIC_00678	326426.Bbr_0186	5.1e-136	384.0	COG1881@1|root,COG1881@2|Bacteria,2I5K1@201174|Actinobacteria,4CZSW@85004|Bifidobacteriales	201174|Actinobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
AKELHBIC_00679	216816.GS08_00840	0.0	1076.0	COG4690@1|root,COG4690@2|Bacteria,2GM80@201174|Actinobacteria,4CZI5@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase family C69	pepD	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
AKELHBIC_00680	216816.GS08_00845	0.0	996.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4CZ7P@85004|Bifidobacteriales	201174|Actinobacteria	F	Formate-tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
AKELHBIC_00681	216816.GS08_00850	5.49e-82	242.0	COG1942@1|root,COG1942@2|Bacteria,2II0W@201174|Actinobacteria,4D0VC@85004|Bifidobacteriales	201174|Actinobacteria	S	Macrophage migration inhibitory factor (MIF)	-	-	-	-	-	-	-	-	-	-	-	-	MIF
AKELHBIC_00682	216816.GS08_00855	1.83e-124	354.0	COG2246@1|root,COG2246@2|Bacteria,2HZBR@201174|Actinobacteria,4CZM6@85004|Bifidobacteriales	201174|Actinobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
AKELHBIC_00683	1437609.BCAL_1651	2.5e-255	711.0	COG2345@1|root,COG2865@1|root,COG2345@2|Bacteria,COG2865@2|Bacteria,2IBE4@201174|Actinobacteria,4D01K@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative DNA-binding domain	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2
AKELHBIC_00684	216816.GS08_00860	0.0	926.0	COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria,4CZ6D@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_00685	216816.GS08_00865	2.93e-157	441.0	COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria,4CZ0Z@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	His_Phos_1
AKELHBIC_00686	216816.GS08_00870	9.75e-202	560.0	2BR5C@1|root,32K3E@2|Bacteria,2I8T9@201174|Actinobacteria,4CZ8U@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00687	216816.GS08_00875	1.67e-217	599.0	COG0676@1|root,COG0676@2|Bacteria,2IIUH@201174|Actinobacteria,4CZWN@85004|Bifidobacteriales	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
AKELHBIC_00688	216816.GS08_00880	6.09e-205	574.0	COG3152@1|root,COG3152@2|Bacteria,2IQHK@201174|Actinobacteria,4D0Q2@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
AKELHBIC_00689	216816.GS08_00920	0.0	998.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CZHK@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iNJ661.Rv2992c	tRNA-synt_1c
AKELHBIC_00691	1437610.BREU_1315	1.45e-35	132.0	COG1373@1|root,COG1373@2|Bacteria,2HVUN@201174|Actinobacteria,4CZHJ@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_00692	1437608.BBIA_0903	2.91e-78	244.0	COG1373@1|root,COG1373@2|Bacteria,2GK1Q@201174|Actinobacteria,4CZNQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_00695	216816.GS08_01855	2.09e-126	361.0	COG2452@1|root,COG2452@2|Bacteria,2IDNQ@201174|Actinobacteria,4CZVV@85004|Bifidobacteriales	201174|Actinobacteria	L	Resolvase, N terminal domain	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07450	-	-	-	-	ko00000	-	-	-	Resolvase
AKELHBIC_00696	33905.BTHE_0571	5.81e-245	681.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4CZ11@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
AKELHBIC_00697	216816.GS08_00935	8.81e-103	298.0	29ZFS@1|root,30MFB@2|Bacteria,2ISQI@201174|Actinobacteria,4D189@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00698	216816.GS08_00940	1.23e-175	492.0	COG3619@1|root,COG3619@2|Bacteria,2GKDV@201174|Actinobacteria,4CZC9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
AKELHBIC_00699	326426.Bbr_0201	0.0	888.0	COG2865@1|root,COG2865@2|Bacteria,2I3IG@201174|Actinobacteria,4CZRW@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_IclR
AKELHBIC_00701	398513.BBNG_00093	0.0	954.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D0BX@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_00702	326426.Bbr_0204	4.43e-25	105.0	COG0331@1|root,COG1028@1|root,COG3321@1|root,COG0331@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,2HZQU@201174|Actinobacteria,4D1A9@85004|Bifidobacteriales	201174|Actinobacteria	IQ	[acyl-carrier-protein] S-malonyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KR,PP-binding,PS-DH
AKELHBIC_00703	216816.GS08_00960	4.51e-148	417.0	COG1309@1|root,COG1309@2|Bacteria,2IRA8@201174|Actinobacteria,4D0DY@85004|Bifidobacteriales	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
AKELHBIC_00704	326426.Bbr_0209	2.73e-120	346.0	COG2977@1|root,COG2977@2|Bacteria,2IIA2@201174|Actinobacteria,4D0IW@85004|Bifidobacteriales	201174|Actinobacteria	Q	4'-phosphopantetheinyl transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
AKELHBIC_00705	326426.Bbr_1114	0.0	956.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_00706	326426.Bbr_1115	8.64e-179	498.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales	201174|Actinobacteria	L	IstB-like ATP binding protein	istB	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
AKELHBIC_00707	1680.BADO_1495	2.62e-27	114.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4D0EV@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
AKELHBIC_00709	216816.GS08_01070	0.0	1062.0	2E07M@1|root,32VVG@2|Bacteria,2ICM1@201174|Actinobacteria,4D036@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00710	216816.GS08_01075	0.0	1150.0	COG0672@1|root,COG0672@2|Bacteria,2GJ22@201174|Actinobacteria,4D01C@85004|Bifidobacteriales	201174|Actinobacteria	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
AKELHBIC_00711	216816.GS08_01080	1.37e-152	430.0	COG3470@1|root,COG3470@2|Bacteria,2GNAD@201174|Actinobacteria,4CZCG@85004|Bifidobacteriales	201174|Actinobacteria	P	Fe2+ transport protein	-	-	-	ko:K07230	-	-	-	-	ko00000,ko02000	2.A.108.2.10,2.A.108.2.4,2.A.108.2.9	-	-	Iron_transport
AKELHBIC_00712	216816.GS08_01085	3.02e-293	801.0	COG4393@1|root,COG4393@2|Bacteria,2GMS6@201174|Actinobacteria,4CZ19@85004|Bifidobacteriales	201174|Actinobacteria	S	Predicted membrane protein (DUF2318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318
AKELHBIC_00713	216816.GS08_01090	2.35e-287	788.0	COG0577@1|root,COG0577@2|Bacteria,2I91N@201174|Actinobacteria,4CZGK@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
AKELHBIC_00714	216816.GS08_01095	2.12e-274	753.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4CZEZ@85004|Bifidobacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
AKELHBIC_00715	216816.GS08_01100	4.85e-188	522.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4CYTA@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_00716	216816.GS08_01105	9.42e-111	320.0	COG3976@1|root,COG3976@2|Bacteria,2IQ4E@201174|Actinobacteria,4D0YM@85004|Bifidobacteriales	201174|Actinobacteria	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
AKELHBIC_00717	216816.GS08_01110	9.91e-137	387.0	COG1309@1|root,COG1309@2|Bacteria,2HZI8@201174|Actinobacteria,4D0IS@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_9,TetR_N
AKELHBIC_00718	216816.GS08_01115	0.0	1238.0	COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ2A@85004|Bifidobacteriales	201174|Actinobacteria	S	YhgE Pip domain protein	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
AKELHBIC_00719	216816.GS08_01120	0.0	1444.0	COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ9R@85004|Bifidobacteriales	201174|Actinobacteria	S	YhgE Pip domain protein	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3
AKELHBIC_00721	216816.GS08_01125	1.29e-297	813.0	COG4905@1|root,COG4905@2|Bacteria,2IBSV@201174|Actinobacteria,4D05G@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
AKELHBIC_00722	326426.Bbr_0232	0.0	947.0	COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4CZFG@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
AKELHBIC_00723	216816.GS08_01135	1.63e-198	550.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4CZRG@85004|Bifidobacteriales	201174|Actinobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
AKELHBIC_00724	216816.GS08_01140	2.27e-247	679.0	COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4CZI4@85004|Bifidobacteriales	201174|Actinobacteria	G	Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
AKELHBIC_00725	216816.GS08_01145	0.0	1027.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CYQM@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
AKELHBIC_00727	77635.BISU_2110	4.54e-184	521.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZ5C@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives	tnp3503b	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00728	405948.SACE_0913	4.45e-12	69.3	2CM5B@1|root,32SDR@2|Bacteria,2IRBQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00730	35754.JNYJ01000002_gene6859	3.9e-15	85.1	COG0477@1|root,COG2814@2|Bacteria,2I8QF@201174|Actinobacteria,4DAU9@85008|Micromonosporales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
AKELHBIC_00731	158787.BSCA_0287	2.44e-27	111.0	COG2197@1|root,COG2197@2|Bacteria,2IGZD@201174|Actinobacteria,4D0TY@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
AKELHBIC_00732	216816.GS08_07040	7.86e-13	78.2	COG4585@1|root,COG4585@2|Bacteria,2I370@201174|Actinobacteria,4D0JE@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00733	857290.HMPREF9156_00676	1.95e-11	61.2	2A7F1@1|root,30WCI@2|Bacteria,2HAHQ@201174|Actinobacteria,4D2PI@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00734	566552.BIFCAT_00154	0.0	920.0	COG4690@1|root,COG4690@2|Bacteria,2GM80@201174|Actinobacteria,4CYT0@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase family C69	-	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
AKELHBIC_00735	566552.BIFCAT_00156	3.18e-237	653.0	COG0463@1|root,COG0463@2|Bacteria,2GMDK@201174|Actinobacteria,4CZIS@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
AKELHBIC_00736	216816.GS08_01165	9.09e-156	443.0	COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria,4CYUD@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	icaR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
AKELHBIC_00737	216816.GS08_01170	1.37e-60	186.0	COG3877@1|root,COG3877@2|Bacteria,2INCH@201174|Actinobacteria,4D10P@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
AKELHBIC_00738	518635.BIFANG_02033	2.16e-28	102.0	2B599@1|root,31Y3D@2|Bacteria,2H050@201174|Actinobacteria,4D1S0@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00739	216816.GS08_01180	1.88e-226	632.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CZZX@85004|Bifidobacteriales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
AKELHBIC_00740	326426.Bbr_0241	3.91e-305	832.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CZA0@85004|Bifidobacteriales	201174|Actinobacteria	U	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
AKELHBIC_00741	216816.GS08_01190	7.34e-72	216.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4D0VD@85004|Bifidobacteriales	201174|Actinobacteria	K	Nitrogen regulatory protein P-II	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
AKELHBIC_00742	216816.GS08_01195	0.0	1199.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4D07P@85004|Bifidobacteriales	201174|Actinobacteria	O	Nucleotidyltransferase domain	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
AKELHBIC_00743	216816.GS08_01200	2.03e-290	799.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,4CZ75@85004|Bifidobacteriales	201174|Actinobacteria	V	MatE	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
AKELHBIC_00744	216816.GS08_01205	0.0	907.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CYY3@85004|Bifidobacteriales	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
AKELHBIC_00745	216816.GS08_01210	0.0	903.0	COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,4CYTP@85004|Bifidobacteriales	201174|Actinobacteria	M	Domain of unknown function (DUF1727)	murE	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
AKELHBIC_00746	216816.GS08_01215	1.1e-181	505.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4CZJ1@85004|Bifidobacteriales	201174|Actinobacteria	S	CobB/CobQ-like glutamine amidotransferase domain	cobQ2	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
AKELHBIC_00747	216816.GS08_01220	3.41e-51	162.0	COG3937@1|root,COG3937@2|Bacteria,2GS3M@201174|Actinobacteria,4D1FE@85004|Bifidobacteriales	201174|Actinobacteria	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
AKELHBIC_00748	326426.Bbr_0249	0.0	1140.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CZ45@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
AKELHBIC_00749	216816.GS08_01230	2.4e-171	481.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4CZUY@85004|Bifidobacteriales	201174|Actinobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
AKELHBIC_00750	216816.GS08_01250	6.23e-243	667.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CZPM@85004|Bifidobacteriales	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
AKELHBIC_00751	216816.GS08_01260	2.77e-64	196.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4D10X@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
AKELHBIC_00752	216816.GS08_01265	4.24e-97	288.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CZ5V@85004|Bifidobacteriales	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
AKELHBIC_00753	216816.GS08_01270	2.15e-48	154.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4D103@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
AKELHBIC_00754	216816.GS08_01275	1.35e-91	269.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4D0P9@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
AKELHBIC_00756	216816.GS08_01285	3.79e-19	79.3	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
AKELHBIC_00757	216816.GS08_01290	1.13e-77	247.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CZ52@85004|Bifidobacteriales	201174|Actinobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N
AKELHBIC_00758	326426.Bbr_0267	2.03e-165	463.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4CZ7F@85004|Bifidobacteriales	201174|Actinobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
AKELHBIC_00759	216816.GS08_01300	0.0	1648.0	COG2217@1|root,COG4633@1|root,COG2217@2|Bacteria,COG4633@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ24@85004|Bifidobacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
AKELHBIC_00760	216816.GS08_01305	9.49e-57	176.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4D1A2@85004|Bifidobacteriales	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042221,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0046688,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
AKELHBIC_00761	216816.GS08_01310	4.94e-284	783.0	COG1322@1|root,COG1322@2|Bacteria,2GP4U@201174|Actinobacteria,4CZA5@85004|Bifidobacteriales	201174|Actinobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
AKELHBIC_00762	1437610.BREU_0461	4.22e-127	363.0	COG0461@1|root,COG0461@2|Bacteria,2HZDS@201174|Actinobacteria,4CZZ6@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE1	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00763	216816.GS08_01320	1.46e-202	560.0	COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4CZE8@85004|Bifidobacteriales	201174|Actinobacteria	J	RNA methyltransferase TrmH family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
AKELHBIC_00764	216816.GS08_01325	2.71e-234	644.0	COG5340@1|root,COG5340@2|Bacteria,2ICPH@201174|Actinobacteria,4CZJ7@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00765	398513.BBNG_01427	1.47e-67	205.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4D10U@85004|Bifidobacteriales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
AKELHBIC_00766	326426.Bbr_0277	0.0	994.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4CZ1X@85004|Bifidobacteriales	201174|Actinobacteria	F	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
AKELHBIC_00767	216816.GS08_01340	0.0	982.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CYUY@85004|Bifidobacteriales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
AKELHBIC_00768	216816.GS08_01345	3.38e-251	689.0	COG1670@1|root,COG1670@2|Bacteria,2I2GV@201174|Actinobacteria,4CYPW@85004|Bifidobacteriales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
AKELHBIC_00769	216816.GS08_01350	2.66e-68	206.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4D0UV@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
AKELHBIC_00770	401473.BDP_1985	0.0	992.0	2DBBJ@1|root,2Z889@2|Bacteria,2GKDX@201174|Actinobacteria,4CZGI@85004|Bifidobacteriales	201174|Actinobacteria	S	Histidine phosphatase superfamily (branch 2)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_2
AKELHBIC_00771	216816.GS08_01355	0.0	1099.0	COG1232@1|root,COG1232@2|Bacteria,2HZ9K@201174|Actinobacteria,4CZ3Z@85004|Bifidobacteriales	201174|Actinobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
AKELHBIC_00772	216816.GS08_01360	0.0	1042.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4CZ2Z@85004|Bifidobacteriales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
AKELHBIC_00774	216816.GS08_01370	6.34e-81	240.0	COG1605@1|root,COG1605@2|Bacteria,2IQ46@201174|Actinobacteria,4D12A@85004|Bifidobacteriales	201174|Actinobacteria	E	Chorismate mutase type II	tyrA	-	5.4.99.5	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
AKELHBIC_00775	216816.GS08_01375	0.0	1098.0	COG1511@1|root,COG1511@2|Bacteria,2I9PN@201174|Actinobacteria,4CZC2@85004|Bifidobacteriales	201174|Actinobacteria	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00776	216816.GS08_01380	0.0	1856.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4CYVG@85004|Bifidobacteriales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
AKELHBIC_00777	216816.GS08_01385	0.0	970.0	COG0747@1|root,COG0747@2|Bacteria,2GM5G@201174|Actinobacteria,4CYUZ@85004|Bifidobacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
AKELHBIC_00778	216816.GS08_01390	4.67e-163	456.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4CZ31@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
AKELHBIC_00779	216816.GS08_01395	1.14e-176	493.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CZB9@85004|Bifidobacteriales	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	glnR	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
AKELHBIC_00780	216816.GS08_01400	1.02e-121	352.0	2A0I6@1|root,30NNB@2|Bacteria,2GJ8M@201174|Actinobacteria,4D0ZN@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00781	326426.Bbr_0294	6.72e-127	362.0	COG1971@1|root,COG1971@2|Bacteria,2GNBU@201174|Actinobacteria,4D01X@85004|Bifidobacteriales	201174|Actinobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
AKELHBIC_00782	216816.GS08_01410	9.28e-118	336.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4CYWS@85004|Bifidobacteriales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
AKELHBIC_00783	216816.GS08_01415	0.0	1465.0	COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria,4CZSK@85004|Bifidobacteriales	201174|Actinobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
AKELHBIC_00784	216816.GS08_01420	0.0	1179.0	COG5624@1|root,COG5624@2|Bacteria,2H7AK@201174|Actinobacteria,4CZMA@85004|Bifidobacteriales	201174|Actinobacteria	K	RNA polymerase II activating transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00787	1403948.Q618_VCMC00001G0002	2.94e-18	79.3	2E3TC@1|root,32DPP@2|Bacteria,2GU2H@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00788	1437610.BREU_0488	1.26e-31	113.0	COG2929@1|root,COG2929@2|Bacteria,2GW9X@201174|Actinobacteria,4D1SS@85004|Bifidobacteriales	201174|Actinobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
AKELHBIC_00789	216816.GS08_01430	1.15e-262	717.0	COG1897@1|root,COG1897@2|Bacteria,2GK5E@201174|Actinobacteria,4CZRK@85004|Bifidobacteriales	201174|Actinobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
AKELHBIC_00790	216816.GS08_01435	2.49e-188	523.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CYZD@85004|Bifidobacteriales	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
AKELHBIC_00791	1437608.BBIA_0293	4.22e-41	135.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,4D16J@85004|Bifidobacteriales	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
AKELHBIC_00792	216816.GS08_01445	1.74e-101	296.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4CYY5@85004|Bifidobacteriales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
AKELHBIC_00793	216816.GS08_01450	1.54e-186	520.0	COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria,4CZ9V@85004|Bifidobacteriales	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
AKELHBIC_00794	216816.GS08_01455	0.0	1058.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CZI7@85004|Bifidobacteriales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
AKELHBIC_00795	216816.GS08_01460	9.04e-205	568.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CYVJ@85004|Bifidobacteriales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
AKELHBIC_00796	216816.GS08_01465	0.0	966.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CZGY@85004|Bifidobacteriales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
AKELHBIC_00797	216816.GS08_01470	2.55e-65	198.0	COG0355@1|root,COG0355@2|Bacteria,2HZPJ@201174|Actinobacteria,4D16F@85004|Bifidobacteriales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
AKELHBIC_00798	216816.GS08_01475	3.64e-174	486.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4CYXA@85004|Bifidobacteriales	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
AKELHBIC_00799	216816.GS08_01480	1.39e-206	574.0	COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,4CZEF@85004|Bifidobacteriales	201174|Actinobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
AKELHBIC_00800	216816.GS08_01485	1.51e-239	660.0	2DMQ0@1|root,32SYI@2|Bacteria,2IA0N@201174|Actinobacteria,4CYQ0@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00801	216816.GS08_01490	1.51e-233	643.0	28PR0@1|root,2ZCCY@2|Bacteria,2GNNZ@201174|Actinobacteria,4CYX7@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00802	216816.GS08_01495	3.99e-212	588.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria,4CZHU@85004|Bifidobacteriales	201174|Actinobacteria	O	Tetratricopeptide repeat	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
AKELHBIC_00803	216816.GS08_01500	3.88e-152	427.0	COG2954@1|root,COG2954@2|Bacteria,2GWD8@201174|Actinobacteria,4CZKD@85004|Bifidobacteriales	201174|Actinobacteria	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00805	216816.GS08_01510	1.82e-80	239.0	COG0251@1|root,COG0251@2|Bacteria,2IFCR@201174|Actinobacteria,4D0QD@85004|Bifidobacteriales	201174|Actinobacteria	J	Endoribonuclease L-PSP	psp1	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
AKELHBIC_00806	216816.GS08_01515	1.93e-232	638.0	COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria,4CZG0@85004|Bifidobacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
AKELHBIC_00807	216816.GS08_01520	9.31e-227	626.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4CZHP@85004|Bifidobacteriales	201174|Actinobacteria	I	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
AKELHBIC_00808	216816.GS08_01525	1.59e-288	787.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4CZ1R@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
AKELHBIC_00809	216816.GS08_01530	7.37e-271	742.0	COG1840@1|root,COG1840@2|Bacteria,2GJFH@201174|Actinobacteria,4CZHC@85004|Bifidobacteriales	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
AKELHBIC_00810	216816.GS08_01535	8.65e-205	569.0	COG4132@1|root,COG4132@2|Bacteria,2GNDF@201174|Actinobacteria,4CZHE@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
AKELHBIC_00811	216816.GS08_01540	1.21e-170	480.0	COG1177@1|root,COG1177@2|Bacteria,2GM0E@201174|Actinobacteria,4CZ2N@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
AKELHBIC_00812	216816.GS08_01545	2.85e-285	782.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CZPE@85004|Bifidobacteriales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
AKELHBIC_00813	216816.GS08_01550	9.53e-226	624.0	COG1266@1|root,COG1266@2|Bacteria,2I3DW@201174|Actinobacteria,4CZJZ@85004|Bifidobacteriales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
AKELHBIC_00814	216816.GS08_01555	9.65e-179	499.0	COG0668@1|root,COG0668@2|Bacteria,2GZI1@201174|Actinobacteria,4CZ0A@85004|Bifidobacteriales	201174|Actinobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
AKELHBIC_00815	216816.GS08_01560	0.0	923.0	COG1027@1|root,COG1027@2|Bacteria,2I2HG@201174|Actinobacteria,4CZ6N@85004|Bifidobacteriales	201174|Actinobacteria	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
AKELHBIC_00816	216816.GS08_01565	1.56e-173	484.0	COG1309@1|root,COG1309@2|Bacteria,2I8SX@201174|Actinobacteria,4CZXQ@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
AKELHBIC_00817	216816.GS08_01570	2.44e-304	833.0	COG1073@1|root,COG1073@2|Bacteria,2GMT6@201174|Actinobacteria,4CZ4Q@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974
AKELHBIC_00818	216816.GS08_01575	5.34e-110	317.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4D10F@85004|Bifidobacteriales	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
AKELHBIC_00819	1437610.BREU_0523	7.63e-15	73.2	COG0431@1|root,COG0431@2|Bacteria,2GMA7@201174|Actinobacteria,4D163@85004|Bifidobacteriales	201174|Actinobacteria	S	NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
AKELHBIC_00823	77635.BISU_2110	1.06e-182	518.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZ5C@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives	tnp3503b	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00824	216816.GS08_01635	2.26e-27	100.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
AKELHBIC_00825	216816.GS08_01625	3.04e-32	112.0	2BSWU@1|root,32N0G@2|Bacteria,2HA44@201174|Actinobacteria,4D2Q5@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00826	326426.Bbr_1716	1.58e-241	665.0	COG1476@1|root,COG1476@2|Bacteria,2IBHI@201174|Actinobacteria,4CZ2T@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
AKELHBIC_00827	216816.GS08_01635	1.18e-34	118.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
AKELHBIC_00828	216816.GS08_01640	2.94e-71	214.0	COG3077@1|root,COG3077@2|Bacteria,2IJU2@201174|Actinobacteria,4D0WU@85004|Bifidobacteriales	201174|Actinobacteria	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
AKELHBIC_00829	216816.GS08_01645	3.67e-89	261.0	COG2337@1|root,COG2337@2|Bacteria,2IFQF@201174|Actinobacteria,4D0PF@85004|Bifidobacteriales	201174|Actinobacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00830	216816.GS08_01650	1.38e-169	474.0	COG0789@1|root,COG0789@2|Bacteria,2HZI3@201174|Actinobacteria,4D0I1@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
AKELHBIC_00831	216816.GS08_01655	1.19e-296	810.0	COG2270@1|root,COG2270@2|Bacteria,2GJCW@201174|Actinobacteria,4CZU3@85004|Bifidobacteriales	201174|Actinobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
AKELHBIC_00832	216816.GS08_01660	3.78e-249	683.0	COG0524@1|root,COG0524@2|Bacteria,2IA3T@201174|Actinobacteria,4CYSM@85004|Bifidobacteriales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH,PfkB
AKELHBIC_00833	216816.GS08_01665	3.03e-40	132.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4D17Q@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal L28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
AKELHBIC_00834	216816.GS08_01670	0.0	1515.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CYTV@85004|Bifidobacteriales	201174|Actinobacteria	L	helicase superfamily c-terminal domain	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
AKELHBIC_00835	398513.BBNG_00227	1.77e-131	392.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	steT	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
AKELHBIC_00836	216816.GS08_01675	3.43e-86	262.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZI0@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00837	1437610.BREU_1226	4.6e-253	699.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D0ME@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_00838	1680.BADO_1070	2.7e-143	406.0	COG2801@1|root,COG2801@2|Bacteria,2H928@201174|Actinobacteria,4CZCP@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
AKELHBIC_00839	78346.BRUM_0813	1.45e-98	290.0	COG2963@1|root,COG2963@2|Bacteria,2IF4K@201174|Actinobacteria,4D0JP@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28
AKELHBIC_00840	547043.BIFPSEUDO_03226	3.29e-205	569.0	COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZW4@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AKELHBIC_00841	547043.BIFPSEUDO_03225	5.99e-219	605.0	COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4CZTQ@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AKELHBIC_00842	216816.GS08_01690	5.32e-205	582.0	COG1653@1|root,COG1653@2|Bacteria,2I5GP@201174|Actinobacteria,4D2XQ@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
AKELHBIC_00843	216816.GS08_01695	5.55e-80	249.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4D0EI@85004|Bifidobacteriales	201174|Actinobacteria	M	Enolase C-terminal domain-like	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
AKELHBIC_00844	547043.BIFPSEUDO_03223	1.08e-27	110.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4D0EI@85004|Bifidobacteriales	201174|Actinobacteria	M	Enolase C-terminal domain-like	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
AKELHBIC_00845	543734.LCABL_29330	3.8e-126	377.0	COG0477@1|root,COG2814@2|Bacteria,1TQZ7@1239|Firmicutes,4HERG@91061|Bacilli,3F54C@33958|Lactobacillaceae	91061|Bacilli	EGP	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_00846	37659.JNLN01000001_gene503	1.44e-248	709.0	COG1874@1|root,COG1874@2|Bacteria,1TT9J@1239|Firmicutes,24CY9@186801|Clostridia,36G14@31979|Clostridiaceae	186801|Clostridia	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
AKELHBIC_00848	762211.BSTEL_0015	1.12e-66	227.0	COG1002@1|root,COG1002@2|Bacteria,2IA5I@201174|Actinobacteria,4D1CS@85004|Bifidobacteriales	201174|Actinobacteria	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
AKELHBIC_00849	762211.BSTEL_0015	2.41e-130	402.0	COG1002@1|root,COG1002@2|Bacteria,2IA5I@201174|Actinobacteria,4D1CS@85004|Bifidobacteriales	201174|Actinobacteria	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
AKELHBIC_00850	762211.BSTEL_0015	8.24e-78	259.0	COG1002@1|root,COG1002@2|Bacteria,2IA5I@201174|Actinobacteria,4D1CS@85004|Bifidobacteriales	201174|Actinobacteria	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
AKELHBIC_00851	857290.HMPREF9156_00753	8.88e-51	181.0	COG1002@1|root,COG1002@2|Bacteria,2IA5I@201174|Actinobacteria,4D1CS@85004|Bifidobacteriales	201174|Actinobacteria	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
AKELHBIC_00854	216816.GS08_01725	3.17e-135	384.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4D0GU@85004|Bifidobacteriales	201174|Actinobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
AKELHBIC_00855	216816.GS08_01730	1.11e-196	545.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4CZ7A@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
AKELHBIC_00856	216816.GS08_01735	0.0	1078.0	COG0826@1|root,COG0826@2|Bacteria,2GKTB@201174|Actinobacteria,4CZA1@85004|Bifidobacteriales	201174|Actinobacteria	O	Peptidase family U32 C-terminal domain	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
AKELHBIC_00857	216816.GS08_01740	1.24e-232	640.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CZBI@85004|Bifidobacteriales	201174|Actinobacteria	Q	Multi-copper polyphenol oxidoreductase laccase	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
AKELHBIC_00858	216816.GS08_01745	1.25e-203	564.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4CYVZ@85004|Bifidobacteriales	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	1.1.1.405,2.7.7.40,2.7.7.60	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	M00096	R01525,R02921,R05633	RC00002,RC00089	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
AKELHBIC_00859	216816.GS08_01750	2.31e-157	441.0	COG2039@1|root,COG2039@2|Bacteria,2GN39@201174|Actinobacteria,4CZ57@85004|Bifidobacteriales	201174|Actinobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
AKELHBIC_00860	216816.GS08_01755	2.73e-157	465.0	COG1196@1|root,COG1196@2|Bacteria,2HZ99@201174|Actinobacteria,4CZ0S@85004|Bifidobacteriales	201174|Actinobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
AKELHBIC_00861	216816.GS08_01760	0.0	902.0	COG3579@1|root,COG3579@2|Bacteria,2GNYU@201174|Actinobacteria,4CZDZ@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase C1-like family	pepC2	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1_2
AKELHBIC_00862	216816.GS08_01765	3.63e-269	737.0	COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CZMR@85004|Bifidobacteriales	201174|Actinobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
AKELHBIC_00863	216816.GS08_01770	3.85e-299	815.0	COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CZ7I@85004|Bifidobacteriales	201174|Actinobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
AKELHBIC_00864	216816.GS08_01785	2.99e-159	447.0	COG0775@1|root,COG0775@2|Bacteria,2I8GZ@201174|Actinobacteria,4CYTM@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
AKELHBIC_00865	216816.GS08_01790	5.03e-295	807.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4CZFF@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
AKELHBIC_00866	216816.GS08_01795	3.27e-259	718.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CZ42@85004|Bifidobacteriales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K07636,ko:K07768	ko02020,map02020	M00434,M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4
AKELHBIC_00867	326426.Bbr_1683	5.87e-180	501.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CZTX@85004|Bifidobacteriales	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
AKELHBIC_00868	216816.GS08_01805	6.29e-238	658.0	COG0226@1|root,COG0226@2|Bacteria,2GJXD@201174|Actinobacteria,4CYTZ@85004|Bifidobacteriales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
AKELHBIC_00869	326426.Bbr_1681	3.53e-207	575.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria,4CYV0@85004|Bifidobacteriales	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
AKELHBIC_00870	216816.GS08_01815	2.32e-215	597.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4D2UW@85004|Bifidobacteriales	201174|Actinobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
AKELHBIC_00871	216816.GS08_01820	3.17e-190	527.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4CYVE@85004|Bifidobacteriales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
AKELHBIC_00872	216816.GS08_01825	1.03e-121	348.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CZE2@85004|Bifidobacteriales	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
AKELHBIC_00873	216816.GS08_00995	8.53e-230	634.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZTH@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00874	216816.GS08_01830	0.0	1422.0	COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
AKELHBIC_00875	216816.GS08_01830	3.81e-16	79.3	COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
AKELHBIC_00876	326426.Bbr_0375	1.54e-130	400.0	COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
AKELHBIC_00877	326426.Bbr_0375	5.35e-71	235.0	COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
AKELHBIC_00878	326426.Bbr_0376a	9.63e-14	64.3	29W0J@1|root,30HIU@2|Bacteria,2HBEV@201174|Actinobacteria,4D2JK@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00879	216816.GS08_01845	9.24e-213	587.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4CZB6@85004|Bifidobacteriales	201174|Actinobacteria	C	Oxidoreductase, aldo keto reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
AKELHBIC_00880	216816.GS08_01850	7.35e-249	683.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZ0Y@85004|Bifidobacteriales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
AKELHBIC_00881	1437609.BCAL_1438	2.08e-153	440.0	COG1609@1|root,COG1609@2|Bacteria,2GJDS@201174|Actinobacteria,4CZR6@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00882	1437603.BMON_1236	2.28e-176	505.0	COG1653@1|root,COG1653@2|Bacteria,2HZAD@201174|Actinobacteria,4CZ9S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_00883	1437603.BMON_1237	6.88e-152	434.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZCI@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
AKELHBIC_00884	1437603.BMON_1238	7.48e-143	409.0	COG0395@1|root,COG0395@2|Bacteria,2GM2W@201174|Actinobacteria,4D05E@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
AKELHBIC_00885	1437603.BMON_1239	3.74e-276	781.0	2DC0D@1|root,2ZC7A@2|Bacteria,2GJTX@201174|Actinobacteria,4D0Y0@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00886	1437610.BREU_1590	3.61e-226	630.0	COG3550@1|root,COG3550@2|Bacteria,2IA5Z@201174|Actinobacteria,4D1XC@85004|Bifidobacteriales	201174|Actinobacteria	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
AKELHBIC_00887	216816.GS08_01865	3.36e-61	188.0	COG1396@1|root,COG1396@2|Bacteria,2HZR9@201174|Actinobacteria,4D1D2@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
AKELHBIC_00888	216816.GS08_01870	3.18e-140	396.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4D0C6@85004|Bifidobacteriales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
AKELHBIC_00889	216816.GS08_01875	1.24e-47	152.0	COG1837@1|root,COG1837@2|Bacteria,2IQ4C@201174|Actinobacteria,4D16Z@85004|Bifidobacteriales	201174|Actinobacteria	S	Belongs to the UPF0109 family	-	GO:0008150,GO:0040007	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
AKELHBIC_00890	216816.GS08_01880	1.66e-83	249.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4D0PE@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
AKELHBIC_00891	216816.GS08_01885	1.23e-181	506.0	COG0115@1|root,COG0115@2|Bacteria	2|Bacteria	E	branched-chain-amino-acid transaminase activity	pabC	-	2.6.1.42,2.6.1.85,4.1.3.38	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R01716,R02199,R05553,R10991	RC00006,RC00010,RC00036,RC01418,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
AKELHBIC_00892	216816.GS08_01890	0.0	935.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4D20E@85004|Bifidobacteriales	201174|Actinobacteria	EH	chorismate binding enzyme	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
AKELHBIC_00893	216816.GS08_01895	1.87e-270	739.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4D2XR@85004|Bifidobacteriales	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
AKELHBIC_00894	216816.GS08_01900	4.16e-143	404.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4D024@85004|Bifidobacteriales	201174|Actinobacteria	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
AKELHBIC_00895	216816.GS08_01905	5.44e-299	814.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4D0N2@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
AKELHBIC_00896	216816.GS08_01910	3.04e-105	304.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria,4CZPT@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0040007,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
AKELHBIC_00897	216816.GS08_01915	2.84e-230	638.0	COG3021@1|root,COG3021@2|Bacteria,2GK2H@201174|Actinobacteria,4CYS3@85004|Bifidobacteriales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
AKELHBIC_00898	216816.GS08_01920	0.0	998.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4CYY1@85004|Bifidobacteriales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
AKELHBIC_00899	216816.GS08_01925	5.5e-208	576.0	COG3965@1|root,COG3965@2|Bacteria,2H4CC@201174|Actinobacteria,4CZ1H@85004|Bifidobacteriales	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
AKELHBIC_00900	216816.GS08_01930	0.0	1078.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CZZ9@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
AKELHBIC_00901	216816.GS08_01935	3.75e-175	489.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4CYR4@85004|Bifidobacteriales	201174|Actinobacteria	F	Peptidase C26	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,Methyltransf_11
AKELHBIC_00902	216816.GS08_01940	0.0	1449.0	COG0488@1|root,COG0488@2|Bacteria,2GJ5M@201174|Actinobacteria,4CZCU@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC transporter	yjjK	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
AKELHBIC_00903	1437610.BREU_1819	9.76e-83	246.0	COG1487@1|root,COG1487@2|Bacteria,2IS29@201174|Actinobacteria,4D1D3@85004|Bifidobacteriales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
AKELHBIC_00904	216816.GS08_01945	1.07e-57	179.0	COG4691@1|root,COG4691@2|Bacteria,2GRCV@201174|Actinobacteria,4D1GB@85004|Bifidobacteriales	201174|Actinobacteria	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	Arc
AKELHBIC_00905	216816.GS08_01950	7.31e-118	338.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4CYXX@85004|Bifidobacteriales	201174|Actinobacteria	E	ACT domain	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
AKELHBIC_00906	216816.GS08_01955	0.0	1251.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CYR0@85004|Bifidobacteriales	201174|Actinobacteria	H	Thiamine pyrophosphate enzyme, central domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
AKELHBIC_00907	216816.GS08_01960	1.55e-168	471.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CZ98@85004|Bifidobacteriales	201174|Actinobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
AKELHBIC_00908	216816.GS08_01965	3.14e-42	137.0	COG0333@1|root,COG0333@2|Bacteria,2GQP3@201174|Actinobacteria,4D18N@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
AKELHBIC_00909	216816.GS08_01970	8.82e-154	431.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4CZ0J@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
AKELHBIC_00910	216816.GS08_01975	3.31e-174	490.0	2EKTZ@1|root,33EHP@2|Bacteria,2HZD3@201174|Actinobacteria,4CZV9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00911	216816.GS08_01980	4.94e-114	327.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CYR5@85004|Bifidobacteriales	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
AKELHBIC_00912	216816.GS08_01985	1.59e-68	206.0	2CAFG@1|root,32ZDZ@2|Bacteria,2I800@201174|Actinobacteria,4D107@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
AKELHBIC_00913	216816.GS08_01990	1.93e-241	663.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CZ25@85004|Bifidobacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
AKELHBIC_00914	326426.Bbr_0399	7.11e-91	266.0	COG0789@1|root,COG0789@2|Bacteria,2HZMI@201174|Actinobacteria,4D0Y1@85004|Bifidobacteriales	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
AKELHBIC_00915	216816.GS08_02000	2.16e-149	420.0	2DSRR@1|root,33H72@2|Bacteria,2I2H5@201174|Actinobacteria,4CZAT@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00916	216816.GS08_02005	1.7e-315	859.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CYUR@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
AKELHBIC_00917	326426.Bbr_0312	4.1e-275	756.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D01G@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00918	1437608.BBIA_0616	6.45e-106	317.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_00919	702459.BBPR_1619	5.89e-94	281.0	COG2826@1|root,COG2826@2|Bacteria,2GSCE@201174|Actinobacteria,4D1V0@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_38
AKELHBIC_00920	216816.GS08_02010	1.85e-204	565.0	2B8QT@1|root,3220I@2|Bacteria,2H680@201174|Actinobacteria,4D2CV@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00921	216816.GS08_02015	1.29e-184	513.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4CZBF@85004|Bifidobacteriales	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
AKELHBIC_00922	216816.GS08_02020	2.46e-170	476.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4CZ3F@85004|Bifidobacteriales	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
AKELHBIC_00924	216816.GS08_02030	9.24e-288	788.0	COG2348@1|root,COG2348@2|Bacteria,2HZ91@201174|Actinobacteria,4CYZJ@85004|Bifidobacteriales	201174|Actinobacteria	V	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K12554	ko00550,ko01100,map00550,map01100	-	R08780	RC00055,RC00064	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
AKELHBIC_00925	216816.GS08_02035	1.19e-313	854.0	COG2348@1|root,COG2348@2|Bacteria,2HZ91@201174|Actinobacteria,4CYZJ@85004|Bifidobacteriales	201174|Actinobacteria	V	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K12554	ko00550,ko01100,map00550,map01100	-	R08780	RC00055,RC00064	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
AKELHBIC_00926	216816.GS08_02040	1.74e-310	845.0	COG2348@1|root,COG2348@2|Bacteria,2HZ91@201174|Actinobacteria,4CYZJ@85004|Bifidobacteriales	201174|Actinobacteria	V	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K12554	ko00550,ko01100,map00550,map01100	-	R08780	RC00055,RC00064	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
AKELHBIC_00927	216816.GS08_02045	4.72e-220	609.0	COG0679@1|root,COG0679@2|Bacteria,2GN0R@201174|Actinobacteria,4CZ6C@85004|Bifidobacteriales	201174|Actinobacteria	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
AKELHBIC_00930	216816.GS08_02060	0.0	1137.0	COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4CYVV@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
AKELHBIC_00931	216816.GS08_02065	0.0	894.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,2GN33@201174|Actinobacteria,4D00C@85004|Bifidobacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
AKELHBIC_00932	216816.GS08_02070	0.0	1136.0	COG4986@1|root,COG4986@2|Bacteria,2GNF7@201174|Actinobacteria,4CZJS@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
AKELHBIC_00933	216816.GS08_02075	6.79e-79	234.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4D0V2@85004|Bifidobacteriales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
AKELHBIC_00934	216816.GS08_02080	1.23e-188	525.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CZEY@85004|Bifidobacteriales	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
AKELHBIC_00935	216816.GS08_02085	6.38e-190	528.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4CZ1U@85004|Bifidobacteriales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
AKELHBIC_00936	216816.GS08_02090	3.76e-268	734.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4CYR6@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00937	543734.LCABL_29330	1.67e-116	352.0	COG0477@1|root,COG2814@2|Bacteria,1TQZ7@1239|Firmicutes,4HERG@91061|Bacilli,3F54C@33958|Lactobacillaceae	91061|Bacilli	EGP	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_00938	1416759.AYMR01000006_gene1028	7.62e-171	494.0	COG3669@1|root,COG3669@2|Bacteria,2HUEI@201174|Actinobacteria,4FRB2@85023|Microbacteriaceae	201174|Actinobacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
AKELHBIC_00939	216816.GS08_02135	0.0	1182.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CZZP@85004|Bifidobacteriales	201174|Actinobacteria	I	AMP-binding enzyme	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
AKELHBIC_00940	216816.GS08_02140	1.88e-22	90.1	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	araE	GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	-	ko:K02100	-	-	-	-	ko00000,ko02000	2.A.1.1.2	-	-	Sugar_tr
AKELHBIC_00941	326426.Bbr_0415	7.41e-89	291.0	COG1132@1|root,COG4988@1|root,COG1132@2|Bacteria,COG4988@2|Bacteria,2GITR@201174|Actinobacteria,4CYSB@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.129,3.A.1.21	-	-	ABC_membrane,ABC_tran
AKELHBIC_00942	1437609.BCAL_0907	3.07e-311	878.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria,4CZW6@85004|Bifidobacteriales	201174|Actinobacteria	U	Sugar (and other) transporter	-	-	-	ko:K02100	-	-	-	-	ko00000,ko02000	2.A.1.1.2	-	-	Sugar_tr
AKELHBIC_00943	1437609.BCAL_1108	1.67e-125	377.0	COG4585@1|root,COG4585@2|Bacteria,2I01E@201174|Actinobacteria,4D2MK@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00944	158787.BSCA_0364	2.34e-34	129.0	COG2197@1|root,COG2197@2|Bacteria,2IQKB@201174|Actinobacteria,4D0VR@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
AKELHBIC_00945	76636.JOEC01000001_gene1069	1.95e-26	101.0	2EAM0@1|root,334PN@2|Bacteria,2GWMS@201174|Actinobacteria	201174|Actinobacteria	S	Bacteriocin (Lactococcin_972)	-	-	-	-	-	-	-	-	-	-	-	-	Lactococcin_972
AKELHBIC_00946	1437609.BCAL_1106	1.43e-301	840.0	COG4652@1|root,COG4652@2|Bacteria,2ICAU@201174|Actinobacteria,4D1WE@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00947	1437609.BCAL_1105	2.53e-129	371.0	COG1136@1|root,COG1136@2|Bacteria,2IAY5@201174|Actinobacteria,4D11T@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_00949	216816.GS08_09320	4.29e-31	116.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_00950	326426.Bbr_0420	6.79e-22	99.4	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ38@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location Cytoplasmic, score 8.87	bga1	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
AKELHBIC_00951	216816.GS08_02175	3.84e-217	604.0	COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria,4D040@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
AKELHBIC_00952	216816.GS08_02180	3.45e-106	337.0	COG3867@1|root,COG3867@2|Bacteria,2GP0I@201174|Actinobacteria,4CZYM@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 53	galA	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Big_3,Big_3_5,Big_4,Glyco_hydro_53
AKELHBIC_00953	216816.GS08_02185	1.65e-207	573.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CYUN@85004|Bifidobacteriales	201174|Actinobacteria	S	Oxidoreductase, aldo keto reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
AKELHBIC_00954	216816.GS08_02190	7.42e-174	485.0	COG2356@1|root,COG2356@2|Bacteria,2GJ38@201174|Actinobacteria,4CZCY@85004|Bifidobacteriales	201174|Actinobacteria	L	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524
AKELHBIC_00955	216816.GS08_02200	2.97e-279	769.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4CZZB@85004|Bifidobacteriales	201174|Actinobacteria	P	H( )-stimulated, divalent metal cation uptake system	mntH	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0030001,GO:0034220,GO:0034755,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071421,GO:0071577,GO:0071578,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
AKELHBIC_00956	78346.BRUM_0813	3.4e-97	286.0	COG2963@1|root,COG2963@2|Bacteria,2IF4K@201174|Actinobacteria,4D0JP@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28
AKELHBIC_00957	1680.BADO_1070	2.7e-143	406.0	COG2801@1|root,COG2801@2|Bacteria,2H928@201174|Actinobacteria,4CZCP@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
AKELHBIC_00958	326426.Bbr_0428	0.0	900.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales	201174|Actinobacteria	U	Drug resistance MFS transporter, drug H antiporter-2 family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_00959	1437610.BREU_2357	2.57e-165	474.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4CZV8@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
AKELHBIC_00960	1226325.HMPREF1548_01586	1.37e-213	597.0	2CET6@1|root,2Z92J@2|Bacteria,1TQGV@1239|Firmicutes,24ARS@186801|Clostridia,36RZZ@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00962	702459.BBPR_0778	4.13e-197	553.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_00963	1437610.BREU_1666	7.81e-109	325.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZA9@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
AKELHBIC_00964	326426.Bbr_1074	1.06e-26	102.0	2B7KG@1|root,320RD@2|Bacteria,2H4J4@201174|Actinobacteria,4D260@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00966	1437608.BBIA_0785	3.01e-16	77.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZA9@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
AKELHBIC_00968	1134413.ANNK01000144_gene3847	1.93e-15	77.0	2B0KJ@1|root,31SY8@2|Bacteria,1UAIC@1239|Firmicutes,4IKWU@91061|Bacilli,1ZPB1@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00969	1437610.BREU_1625	3.45e-87	267.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_00970	216816.GS08_09320	2.69e-159	449.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_00971	762211.BSTEL_0160	4.38e-163	461.0	COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4D03A@85004|Bifidobacteriales	201174|Actinobacteria	S	EamA-like transporter family	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
AKELHBIC_00972	216816.GS08_02610	9.68e-163	461.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_00973	326426.Bbr_1114	0.0	956.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_00974	326426.Bbr_1115	8.64e-179	498.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales	201174|Actinobacteria	L	IstB-like ATP binding protein	istB	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
AKELHBIC_00975	77635.BISU_2110	1.06e-182	518.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZ5C@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives	tnp3503b	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00976	525246.HMPREF0058_1985	1.46e-15	79.0	COG3064@1|root,COG3064@2|Bacteria,2GQVM@201174|Actinobacteria,4D803@85005|Actinomycetales	201174|Actinobacteria	M	Excalibur calcium-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur
AKELHBIC_00977	78345.BMERY_0912	1.01e-56	182.0	2C9KH@1|root,33E34@2|Bacteria,2HZZG@201174|Actinobacteria,4D2DM@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00978	78345.BMERY_0913	1.29e-25	99.4	COG1598@1|root,COG1598@2|Bacteria,2GZ8D@201174|Actinobacteria,4D2M2@85004|Bifidobacteriales	201174|Actinobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00979	78345.BMERY_0914	5.75e-31	110.0	COG1724@1|root,COG1724@2|Bacteria,2GX5V@201174|Actinobacteria,4D2IM@85004|Bifidobacteriales	201174|Actinobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
AKELHBIC_00980	1437608.BBIA_2190	1.19e-172	494.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZKR@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	int8	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
AKELHBIC_00981	1437608.BBIA_0616	2.37e-184	526.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_00983	1437608.BBIA_2590	7.88e-72	228.0	COG0842@1|root,COG0842@2|Bacteria,2IQ57@201174|Actinobacteria,4D0ZR@85004|Bifidobacteriales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
AKELHBIC_00984	1437608.BBIA_2591	2.15e-115	345.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4D2RY@85004|Bifidobacteriales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_00987	1437610.BREU_1925	4.32e-32	123.0	COG2197@1|root,COG2197@2|Bacteria,2IJP9@201174|Actinobacteria,4D0Z2@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
AKELHBIC_00989	216816.GS08_02610	3.21e-168	475.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_00990	77635.BISU_2110	1.06e-182	518.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZ5C@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives	tnp3503b	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_00992	1437609.BCAL_0537	1.12e-42	143.0	2BH3J@1|root,32B4F@2|Bacteria,2IHK5@201174|Actinobacteria,4D0RP@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_00993	1437609.BCAL_0606	4.32e-298	813.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZA9@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
AKELHBIC_00994	1437609.BCAL_0605	1.47e-101	299.0	2DQQK@1|root,33842@2|Bacteria,2GS39@201174|Actinobacteria,4D0HX@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
AKELHBIC_00995	1437609.BCAL_0604	6.28e-165	462.0	29YC4@1|root,30K6H@2|Bacteria,2H0Z2@201174|Actinobacteria,4D0DD@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
AKELHBIC_00998	1437609.BCAL_0599	1.81e-310	845.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZA9@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
AKELHBIC_00999	1437609.BCAL_0598	7.39e-134	399.0	COG3525@1|root,COG3525@2|Bacteria,2HZCI@201174|Actinobacteria,4CZS1@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
AKELHBIC_01000	326426.Bbr_1556	3.67e-172	499.0	COG3525@1|root,COG3525@2|Bacteria,2HZCI@201174|Actinobacteria,4CZS1@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
AKELHBIC_01001	326426.Bbr_1073	1.27e-86	255.0	2B3VD@1|root,31QFH@2|Bacteria,2IS1C@201174|Actinobacteria,4D1BE@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01002	326426.Bbr_1072	2.76e-216	596.0	COG1131@1|root,COG1131@2|Bacteria,2GNQJ@201174|Actinobacteria,4D0SJ@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
AKELHBIC_01003	326426.Bbr_1071	5.17e-176	491.0	2B5A1@1|root,31Y46@2|Bacteria,2HZNW@201174|Actinobacteria,4D13D@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
AKELHBIC_01004	326426.Bbr_1070	8.36e-138	390.0	2AYSN@1|root,31QXY@2|Bacteria,2ISV3@201174|Actinobacteria,4D18V@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01006	326426.Bbr_1068	2.71e-124	355.0	COG1595@1|root,COG1595@2|Bacteria,2HG2H@201174|Actinobacteria,4D1CQ@85004|Bifidobacteriales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
AKELHBIC_01007	702459.BBPR_1115	3.95e-147	425.0	COG4767@1|root,COG4767@2|Bacteria,2H595@201174|Actinobacteria,4CZBZ@85004|Bifidobacteriales	201174|Actinobacteria	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	RDD,VanZ
AKELHBIC_01009	649743.HMPREF0972_00933	7.55e-131	393.0	COG4403@1|root,COG4403@2|Bacteria,2GPKJ@201174|Actinobacteria,4D73I@85005|Actinomycetales	201174|Actinobacteria	V	Psort location Cytoplasmic, score	-	-	-	ko:K20484	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	LANC_like
AKELHBIC_01010	649743.HMPREF0972_00932	8.19e-187	578.0	2C4IS@1|root,2Z81U@2|Bacteria,2GP0Z@201174|Actinobacteria,4D71C@85005|Actinomycetales	201174|Actinobacteria	S	Thiopeptide-type bacteriocin biosynthesis domain protein	-	-	-	ko:K20483	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	Lant_dehydr_C,Lant_dehydr_N
AKELHBIC_01012	1437610.BREU_1690	0.0	1060.0	COG1132@1|root,COG1132@2|Bacteria,2GJTA@201174|Actinobacteria,4D20I@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Transglut_core3
AKELHBIC_01013	1437610.BREU_1691	1.82e-93	273.0	2D1GW@1|root,32TAQ@2|Bacteria,2IQ3W@201174|Actinobacteria	201174|Actinobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core3
AKELHBIC_01014	1437610.BREU_1692	2.87e-42	152.0	COG0367@1|root,COG0367@2|Bacteria,2GMIY@201174|Actinobacteria,4D1Z9@85004|Bifidobacteriales	201174|Actinobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
AKELHBIC_01015	1437609.BCAL_0580	0.0	1004.0	COG0367@1|root,COG0367@2|Bacteria,2GMIY@201174|Actinobacteria,4D1Z9@85004|Bifidobacteriales	201174|Actinobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
AKELHBIC_01016	1437609.BCAL_0579	1.06e-24	92.0	2BEP0@1|root,328EK@2|Bacteria,2HE79@201174|Actinobacteria,4D2MJ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01017	1437609.BCAL_0578	2.21e-156	439.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4D00Y@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_01018	1437609.BCAL_0577	1.55e-160	450.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4D0EU@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
AKELHBIC_01019	1437609.BCAL_0576	3.12e-291	798.0	COG4585@1|root,COG4585@2|Bacteria,2GVYN@201174|Actinobacteria,4D1I8@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
AKELHBIC_01020	1437608.BBIA_0798	1.16e-23	96.3	COG3505@1|root,COG3505@2|Bacteria,2HZ9D@201174|Actinobacteria,4CZ1V@85004|Bifidobacteriales	201174|Actinobacteria	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
AKELHBIC_01023	1437608.BBIA_0802	6.33e-155	442.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4D00Y@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
AKELHBIC_01026	216816.GS08_02610	8.49e-255	699.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_01027	216816.GS08_05135	8.73e-154	432.0	COG1131@1|root,COG1131@2|Bacteria,2IEJK@201174|Actinobacteria,4D0K4@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_01028	216816.GS08_05140	3.3e-138	394.0	2EXFX@1|root,33QS8@2|Bacteria,2IC7Z@201174|Actinobacteria,4CZUQ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01029	762211.BSTEL_0148	2.76e-104	306.0	2F10A@1|root,33U1T@2|Bacteria,2IAKS@201174|Actinobacteria,4D01S@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01030	1437608.BBIA_0816	1.07e-237	697.0	COG3064@1|root,COG3064@2|Bacteria,2I2HK@201174|Actinobacteria,4D2VM@85004|Bifidobacteriales	201174|Actinobacteria	M	Cell surface antigen C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Antigen_C
AKELHBIC_01033	77635.BISU_1251	6.52e-157	454.0	COG2856@1|root,COG2856@2|Bacteria,2GRH0@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_M78
AKELHBIC_01034	1437608.BBIA_0818	2.46e-36	125.0	2B6SJ@1|root,31ZRP@2|Bacteria,2IQ17@201174|Actinobacteria,4D142@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01035	1437609.BCAL_0537	1.03e-91	268.0	2BH3J@1|root,32B4F@2|Bacteria,2IHK5@201174|Actinobacteria,4D0RP@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01036	1437608.BBIA_0820	1.43e-47	152.0	2AYK3@1|root,31QQD@2|Bacteria,2ISGT@201174|Actinobacteria,4D1C9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01037	1437608.BBIA_0821	5.1e-134	380.0	COG1192@1|root,COG1192@2|Bacteria,2ICWE@201174|Actinobacteria,4D14U@85004|Bifidobacteriales	201174|Actinobacteria	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
AKELHBIC_01038	1437609.BCAL_0534	3.71e-127	361.0	2A2Z4@1|root,30RDK@2|Bacteria,2IDG0@201174|Actinobacteria,4D038@85004|Bifidobacteriales	201174|Actinobacteria	S	Transcription factor WhiB	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
AKELHBIC_01039	1437609.BCAL_0532	2.59e-296	808.0	29W79@1|root,30HSG@2|Bacteria,2IC42@201174|Actinobacteria,4CZCZ@85004|Bifidobacteriales	201174|Actinobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36
AKELHBIC_01040	1437608.BBIA_0824	3.18e-30	107.0	2BA3Q@1|root,323HI@2|Bacteria,2H863@201174|Actinobacteria,4D2FS@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01041	1437608.BBIA_0825	4.53e-16	72.8	2AWD3@1|root,31N90@2|Bacteria,2IP9B@201174|Actinobacteria,4D14C@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01043	216816.GS08_08540	8.11e-202	559.0	COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria,4CZKF@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
AKELHBIC_01044	216816.GS08_08535	2.29e-254	696.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4CZDB@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
AKELHBIC_01047	216816.GS08_00995	7.01e-229	632.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZTH@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01048	216816.GS08_08520	4.42e-136	394.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria,4D016@85004|Bifidobacteriales	201174|Actinobacteria	M	Mycolic acid cyclopropane synthetase	cfa	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
AKELHBIC_01049	216816.GS08_08520	2.87e-41	146.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria,4D016@85004|Bifidobacteriales	201174|Actinobacteria	M	Mycolic acid cyclopropane synthetase	cfa	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
AKELHBIC_01050	216816.GS08_08520	1.02e-91	281.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria,4D016@85004|Bifidobacteriales	201174|Actinobacteria	M	Mycolic acid cyclopropane synthetase	cfa	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
AKELHBIC_01051	216816.GS08_08515	3.91e-267	732.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CZ71@85004|Bifidobacteriales	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	fucO	-	1.1.1.77,1.1.99.37,1.2.98.1	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	-	R00614,R01781,R02257	RC00034,RC00087,RC00099,RC00188	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
AKELHBIC_01052	216816.GS08_08510	5.43e-227	624.0	COG1215@1|root,COG1215@2|Bacteria,2GNPU@201174|Actinobacteria,4CZ7E@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
AKELHBIC_01053	216816.GS08_08505	0.0	986.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4CZD1@85004|Bifidobacteriales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
AKELHBIC_01054	216816.GS08_08500	1.14e-294	804.0	COG1215@1|root,COG1215@2|Bacteria,2HZ9V@201174|Actinobacteria,4CZ5J@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
AKELHBIC_01055	216816.GS08_08495	4.48e-206	571.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CZ0Q@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_01056	216816.GS08_08490	0.0	1038.0	2BWH2@1|root,2Z89R@2|Bacteria,2GMNW@201174|Actinobacteria,4CZP3@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
AKELHBIC_01057	216816.GS08_08485	0.0	891.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4CYXQ@85004|Bifidobacteriales	201174|Actinobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
AKELHBIC_01058	216816.GS08_08480	2.1e-269	738.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CYSY@85004|Bifidobacteriales	201174|Actinobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
AKELHBIC_01059	216816.GS08_08475	2.03e-124	355.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CZNJ@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
AKELHBIC_01060	216816.GS08_08470	0.0	1323.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CZ6U@85004|Bifidobacteriales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
AKELHBIC_01062	216816.GS08_08460	7.27e-139	392.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4CZ5S@85004|Bifidobacteriales	201174|Actinobacteria	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
AKELHBIC_01063	216816.GS08_08455	1.25e-203	564.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CZWW@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
AKELHBIC_01064	216816.GS08_08450	0.0	917.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,2H3G6@201174|Actinobacteria,4D0EJ@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
AKELHBIC_01065	216816.GS08_08445	3.16e-119	341.0	2DRQG@1|root,33CMQ@2|Bacteria,2HZP6@201174|Actinobacteria,4D14M@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3180)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3180
AKELHBIC_01066	216816.GS08_08440	9.18e-211	583.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4CZRC@85004|Bifidobacteriales	201174|Actinobacteria	I	Thioesterase-like superfamily	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
AKELHBIC_01067	702459.BBPR_1438	0.0	1190.0	COG3525@1|root,COG5492@1|root,COG3525@2|Bacteria,COG5492@2|Bacteria,2GK90@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase family 20, catalytic	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Big_2,F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,NPCBM_assoc,RicinB_lectin_2
AKELHBIC_01068	216816.GS08_08435	0.0	1112.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4CYWH@85004|Bifidobacteriales	201174|Actinobacteria	S	ATP-binding cassette protein, ChvD family	yjjK	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
AKELHBIC_01070	1280671.AUJH01000004_gene2770	5.6e-25	102.0	2E5U7@1|root,330IH@2|Bacteria,1VIPX@1239|Firmicutes,24R2I@186801|Clostridia,4BZZS@830|Butyrivibrio	186801|Clostridia	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
AKELHBIC_01071	1280679.ATVX01000012_gene2534	8.28e-36	122.0	COG3655@1|root,COG3655@2|Bacteria,1W0PD@1239|Firmicutes,252UZ@186801|Clostridia,4BZYE@830|Butyrivibrio	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
AKELHBIC_01073	216816.GS08_05945	1.54e-80	240.0	COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,rve,rve_2
AKELHBIC_01074	398513.BBNG_01665	9.13e-65	203.0	2EINA@1|root,33CDM@2|Bacteria,2ICYX@201174|Actinobacteria,4CZUT@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01075	216816.GS08_06345	4.16e-121	353.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4D06Q@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_01076	401473.BDP_1060	8.35e-317	908.0	COG0577@1|root,COG0577@2|Bacteria,2GN24@201174|Actinobacteria,4D07Y@85004|Bifidobacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
AKELHBIC_01077	401473.BDP_1061	1.42e-78	240.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4D0ZC@85004|Bifidobacteriales	201174|Actinobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
AKELHBIC_01079	326426.Bbr_1489	0.0	1021.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D0BX@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_01081	216816.GS08_08420	3.95e-224	618.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4CZF6@85004|Bifidobacteriales	201174|Actinobacteria	G	ROK family	glkA	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
AKELHBIC_01082	216816.GS08_08380	1.36e-42	149.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4D2XT@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_01083	216816.GS08_08375	1.35e-205	568.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CYUN@85004|Bifidobacteriales	201174|Actinobacteria	S	Oxidoreductase, aldo keto reductase family protein	dkg	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
AKELHBIC_01084	158787.BSCA_2217	3.84e-89	262.0	COG0242@1|root,COG0242@2|Bacteria,2IJQ5@201174|Actinobacteria,4D14S@85004|Bifidobacteriales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	fms	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
AKELHBIC_01085	216816.GS08_08365	3.39e-184	513.0	2A54I@1|root,30TT6@2|Bacteria,2IETW@201174|Actinobacteria,4CZX3@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01086	1437609.BCAL_0501	2.87e-23	99.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales	201174|Actinobacteria	U	Drug resistance MFS transporter, drug H antiporter-2 family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_01087	216816.GS08_08355	7.45e-33	114.0	COG0477@1|root,COG2814@2|Bacteria,2H8SZ@201174|Actinobacteria,4D2D2@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_01088	216816.GS08_08240	8.39e-85	265.0	COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4CZH0@85004|Bifidobacteriales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, C-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
AKELHBIC_01089	216816.GS08_08235	5.8e-289	790.0	COG1940@1|root,COG1940@2|Bacteria,2GJIE@201174|Actinobacteria,4CZPD@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	xylR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,MarR_2,ROK
AKELHBIC_01091	216816.GS08_08225	6.44e-49	155.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4D17F@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds the 23S rRNA	rpmE	GO:0008150,GO:0040007	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
AKELHBIC_01092	216816.GS08_08220	9.57e-246	676.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4CYX4@85004|Bifidobacteriales	201174|Actinobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0008150,GO:0040007	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
AKELHBIC_01093	326426.Bbr_1480	6.13e-201	557.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CZB3@85004|Bifidobacteriales	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25,Methyltransf_31
AKELHBIC_01094	326426.Bbr_1479	3.32e-265	728.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CZYU@85004|Bifidobacteriales	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
AKELHBIC_01095	326426.Bbr_1478	6.95e-170	480.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4CZQ6@85004|Bifidobacteriales	201174|Actinobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
AKELHBIC_01096	326426.Bbr_1477	1.66e-217	605.0	COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4CYTE@85004|Bifidobacteriales	201174|Actinobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
AKELHBIC_01097	326426.Bbr_1476	1.49e-193	538.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CZBX@85004|Bifidobacteriales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
AKELHBIC_01098	326426.Bbr_1475	1.08e-155	438.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CZE0@85004|Bifidobacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	livF	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
AKELHBIC_01099	216816.GS08_00995	8.53e-230	634.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZTH@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01100	216816.GS08_08205	1.68e-154	434.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4CYVA@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
AKELHBIC_01101	216816.GS08_08200	9.99e-274	753.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CZ4P@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
AKELHBIC_01102	216816.GS08_08195	0.0	998.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria,4CZ2S@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
AKELHBIC_01103	1437610.BREU_1275	4.86e-150	422.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4CYZY@85004|Bifidobacteriales	201174|Actinobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
AKELHBIC_01104	216816.GS08_08185	0.0	923.0	COG0507@1|root,COG0507@2|Bacteria,2HFY1@201174|Actinobacteria,4CZ0C@85004|Bifidobacteriales	201174|Actinobacteria	L	PIF1-like helicase	-	-	-	-	-	-	-	-	-	-	-	-	PIF1
AKELHBIC_01105	216816.GS08_08180	3.44e-77	246.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,2ISCW@201174|Actinobacteria,4D0HC@85004|Bifidobacteriales	201174|Actinobacteria	S	AMMECR1	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
AKELHBIC_01106	216816.GS08_08180	5.14e-43	153.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,2ISCW@201174|Actinobacteria,4D0HC@85004|Bifidobacteriales	201174|Actinobacteria	S	AMMECR1	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
AKELHBIC_01108	216816.GS08_08165	0.0	1194.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CZ6E@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
AKELHBIC_01109	216816.GS08_08160	6.86e-70	221.0	COG0629@1|root,COG0629@2|Bacteria,2GQIQ@201174|Actinobacteria,4D17E@85004|Bifidobacteriales	201174|Actinobacteria	L	Single-strand binding protein family	ssb2	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
AKELHBIC_01110	216816.GS08_08155	0.0	1434.0	COG3590@1|root,COG3590@2|Bacteria,2GNJY@201174|Actinobacteria,4CYVU@85004|Bifidobacteriales	201174|Actinobacteria	O	Peptidase family M13	pepO	-	3.4.24.11,3.4.24.71	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
AKELHBIC_01111	216816.GS08_08150	6.42e-180	507.0	COG3247@1|root,COG3247@2|Bacteria,2H3AT@201174|Actinobacteria,4D00R@85004|Bifidobacteriales	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
AKELHBIC_01112	216816.GS08_08145	1.07e-193	536.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CZAA@85004|Bifidobacteriales	201174|Actinobacteria	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
AKELHBIC_01113	216816.GS08_08140	1.05e-313	854.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CZ2J@85004|Bifidobacteriales	201174|Actinobacteria	C	Citrate synthase, C-terminal domain	gltA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
AKELHBIC_01114	216816.GS08_08135	2.74e-222	615.0	COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,4CYVT@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1201c	Hexapep_2,THDPS_M
AKELHBIC_01115	216816.GS08_08130	1.47e-269	736.0	COG2378@1|root,COG2378@2|Bacteria,2IAIA@201174|Actinobacteria,4CYRS@85004|Bifidobacteriales	201174|Actinobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
AKELHBIC_01116	216816.GS08_08125	0.0	2666.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,2GISC@201174|Actinobacteria,4CZSD@85004|Bifidobacteriales	201174|Actinobacteria	KL	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
AKELHBIC_01117	216816.GS08_08110	3.33e-46	150.0	COG0454@1|root,COG0456@2|Bacteria,2II91@201174|Actinobacteria,4D0SH@85004|Bifidobacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
AKELHBIC_01118	216816.GS08_08105	5.51e-109	314.0	COG3727@1|root,COG3727@2|Bacteria,2IKPY@201174|Actinobacteria,4D0R6@85004|Bifidobacteriales	201174|Actinobacteria	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
AKELHBIC_01119	216816.GS08_08100	8.57e-248	681.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4CYXG@85004|Bifidobacteriales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
AKELHBIC_01120	216816.GS08_08095	1.33e-293	801.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZQP@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class-V	aspB	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
AKELHBIC_01121	216816.GS08_08090	1e-45	156.0	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4CYW8@85004|Bifidobacteriales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx1	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
AKELHBIC_01122	216816.GS08_08085	4.37e-246	678.0	COG3568@1|root,COG3568@2|Bacteria,2I2GX@201174|Actinobacteria,4CYTX@85004|Bifidobacteriales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	ko:K18353	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	Exo_endo_phos
AKELHBIC_01124	216816.GS08_08070	1.01e-99	289.0	COG3613@1|root,COG3613@2|Bacteria,2IHGG@201174|Actinobacteria,4D0T2@85004|Bifidobacteriales	201174|Actinobacteria	F	Nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
AKELHBIC_01125	216816.GS08_08060	0.0	1207.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYYC@85004|Bifidobacteriales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
AKELHBIC_01126	216816.GS08_08055	4.17e-119	340.0	COG2249@1|root,COG2249@2|Bacteria,2HZE1@201174|Actinobacteria,4D11H@85004|Bifidobacteriales	201174|Actinobacteria	S	Flavodoxin-like fold	ywrO	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
AKELHBIC_01127	216816.GS08_08045	1.05e-295	805.0	COG3550@1|root,COG3550@2|Bacteria,2GZFV@201174|Actinobacteria,4D1TH@85004|Bifidobacteriales	201174|Actinobacteria	S	peptidyl-serine autophosphorylation	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01128	216816.GS08_08040	6.67e-58	180.0	COG1722@1|root,COG1722@2|Bacteria,2GR0U@201174|Actinobacteria,4D18C@85004|Bifidobacteriales	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
AKELHBIC_01129	216816.GS08_08035	0.0	875.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4CZU4@85004|Bifidobacteriales	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
AKELHBIC_01130	216816.GS08_08030	0.0	1652.0	COG1328@1|root,COG1328@2|Bacteria,2GMGA@201174|Actinobacteria,4CYV3@85004|Bifidobacteriales	201174|Actinobacteria	F	Anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
AKELHBIC_01131	326426.Bbr_1446	3.06e-184	511.0	COG0602@1|root,COG0602@2|Bacteria,2H0HA@201174|Actinobacteria,4CYSC@85004|Bifidobacteriales	201174|Actinobacteria	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
AKELHBIC_01132	216816.GS08_08020	0.0	3258.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2I1VH@201174|Actinobacteria,4CZ6Y@85004|Bifidobacteriales	201174|Actinobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
AKELHBIC_01133	216816.GS08_08015	0.0	879.0	COG3572@1|root,COG3572@2|Bacteria,2GJPI@201174|Actinobacteria,4CYZP@85004|Bifidobacteriales	201174|Actinobacteria	H	Glutamate-cysteine ligase family 2(GCS2)	egtA	GO:0003674,GO:0003824,GO:0004357,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0044464,GO:0071944	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3704c	GCS2
AKELHBIC_01134	216816.GS08_08005	5.45e-23	97.4	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZT6@85004|Bifidobacteriales	201174|Actinobacteria	G	Fibronectin type III-like domain	bgl2	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
AKELHBIC_01135	216816.GS08_08005	1.88e-34	132.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZT6@85004|Bifidobacteriales	201174|Actinobacteria	G	Fibronectin type III-like domain	bgl2	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
AKELHBIC_01136	158787.BSCA_0782	1.44e-61	189.0	COG1669@1|root,COG1669@2|Bacteria,2IMP4@201174|Actinobacteria,4D145@85004|Bifidobacteriales	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
AKELHBIC_01137	326426.Bbr_1439	3.1e-92	269.0	COG1669@1|root,COG1669@2|Bacteria,2IJSQ@201174|Actinobacteria,4D0XU@85004|Bifidobacteriales	201174|Actinobacteria	S	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
AKELHBIC_01138	216816.GS08_07990	5.25e-296	807.0	COG2730@1|root,COG2730@2|Bacteria,2I8WH@201174|Actinobacteria,4CZV7@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4,3.2.1.58	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	-	R00308,R03115,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
AKELHBIC_01139	1437610.BREU_0902	3.12e-107	312.0	COG1309@1|root,COG1309@2|Bacteria,2I8DN@201174|Actinobacteria,4CZXN@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
AKELHBIC_01140	1437610.BREU_0903	0.0	1310.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZ2P@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 3 N-terminal domain protein	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
AKELHBIC_01141	326426.Bbr_0040	0.0	1383.0	COG0451@1|root,COG0451@2|Bacteria,2ICHN@201174|Actinobacteria,4CYZ7@85004|Bifidobacteriales	201174|Actinobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
AKELHBIC_01142	216816.GS08_07970	3.18e-208	577.0	28H6W@1|root,2Z7J7@2|Bacteria,2ICGP@201174|Actinobacteria,4CZUA@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01143	216816.GS08_07965	0.0	1202.0	COG4878@1|root,COG4878@2|Bacteria,2IERA@201174|Actinobacteria,4D00K@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterised protein conserved in bacteria (DUF2194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2194
AKELHBIC_01144	326426.Bbr_0044	0.0	961.0	COG0438@1|root,COG0438@2|Bacteria,2GKEA@201174|Actinobacteria,4CZ5G@85004|Bifidobacteriales	201174|Actinobacteria	M	Domain of unknown function (DUF3492)	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glyco_trans_1_4,Glycos_transf_1
AKELHBIC_01145	216816.GS08_07955	0.0	976.0	COG4267@1|root,COG4267@2|Bacteria,2IE76@201174|Actinobacteria,4CZ7D@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative exopolysaccharide Exporter (EPS-E)	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
AKELHBIC_01146	216816.GS08_07950	0.0	1144.0	COG5337@1|root,COG5337@2|Bacteria,2ID5Z@201174|Actinobacteria,4D02F@85004|Bifidobacteriales	201174|Actinobacteria	M	CotH kinase protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
AKELHBIC_01147	216816.GS08_07945	1.52e-200	555.0	COG5036@1|root,COG5036@2|Bacteria,2HZIY@201174|Actinobacteria,4D0MA@85004|Bifidobacteriales	201174|Actinobacteria	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
AKELHBIC_01148	216816.GS08_07940	2e-141	400.0	COG1285@1|root,COG1285@2|Bacteria,2HZFV@201174|Actinobacteria,4D0AX@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
AKELHBIC_01149	216816.GS08_07935	0.0	1374.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,2I2FR@201174|Actinobacteria,4D09B@85004|Bifidobacteriales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	3.1.4.52	ko:K14051	ko02024,ko02026,map02024,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4
AKELHBIC_01150	216816.GS08_07930	0.0	1141.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZMX@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AKELHBIC_01151	216816.GS08_07925	0.0	1283.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZPJ@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AKELHBIC_01152	216816.GS08_07920	4.71e-59	192.0	COG1609@1|root,COG1609@2|Bacteria,2GNVD@201174|Actinobacteria,4CZNG@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	rbsR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
AKELHBIC_01153	547043.BIFPSEUDO_02356	2.6e-209	580.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZIN@85004|Bifidobacteriales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	rihB	-	3.2.2.1,3.2.2.8	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	-	R01245,R01273,R01677,R01770,R02137,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
AKELHBIC_01154	547043.BIFPSEUDO_02355	3.46e-250	697.0	COG0477@1|root,COG2814@2|Bacteria,2H8UD@201174|Actinobacteria,4CZ16@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
AKELHBIC_01155	1437603.BMON_0302	8.18e-44	152.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZ0Y@85004|Bifidobacteriales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	iunH2	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
AKELHBIC_01156	158787.BSCA_0809	1e-40	145.0	COG0477@1|root,COG0477@2|Bacteria,2GJV6@201174|Actinobacteria,4CZH3@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08168	-	M00704	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3.16,2.A.1.3.22,2.A.1.3.6	-	-	MFS_1
AKELHBIC_01157	158787.BSCA_0810	2.87e-206	573.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CZIB@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
AKELHBIC_01158	216816.GS08_07885	3.76e-223	617.0	COG1609@1|root,COG1609@2|Bacteria,2H5ZG@201174|Actinobacteria,4CZ8A@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulator, LacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
AKELHBIC_01159	1437603.BMON_1678	3.27e-138	396.0	COG2186@1|root,COG2186@2|Bacteria,2GJ82@201174|Actinobacteria,4D0K7@85004|Bifidobacteriales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
AKELHBIC_01160	1437603.BMON_1677	4.94e-182	510.0	COG0648@1|root,COG0648@2|Bacteria,2I8IU@201174|Actinobacteria,4D0HP@85004|Bifidobacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF4862)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4862
AKELHBIC_01161	1437603.BMON_1676	2.63e-152	436.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4D0EX@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
AKELHBIC_01162	1437603.BMON_1675	1.59e-147	417.0	COG3010@1|root,COG3010@2|Bacteria,2GTWV@201174|Actinobacteria,4CZK9@85004|Bifidobacteriales	201174|Actinobacteria	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
AKELHBIC_01163	1437603.BMON_1674	0.0	1192.0	COG4409@1|root,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria,4D02H@85004|Bifidobacteriales	201174|Actinobacteria	G	BNR repeat-like domain	neu	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Laminin_G_3
AKELHBIC_01164	1437603.BMON_1673	0.0	939.0	COG0747@1|root,COG0747@2|Bacteria,2GK4Y@201174|Actinobacteria,4CYSK@85004|Bifidobacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA7	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5,TAT_signal
AKELHBIC_01165	1437603.BMON_1672	9.16e-215	594.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4D2RG@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	oppB6	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
AKELHBIC_01166	1437603.BMON_1671	0.0	1238.0	COG0444@1|root,COG1173@1|root,COG0444@2|Bacteria,COG1173@2|Bacteria,2GIXV@201174|Actinobacteria,4D0C4@85004|Bifidobacteriales	201174|Actinobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	oppCD2	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,OppC_N,oligo_HPY
AKELHBIC_01167	1437603.BMON_1670	5.48e-181	506.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4CYR3@85004|Bifidobacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	oppF	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
AKELHBIC_01168	1437603.BMON_1669	4.26e-206	573.0	COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4D04B@85004|Bifidobacteriales	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	nanA	-	4.1.3.3,4.3.3.7	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01811,R10147	RC00159,RC00600,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
AKELHBIC_01169	216816.GS08_07875	1.85e-307	836.0	COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4CZFH@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase, class I II	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
AKELHBIC_01170	216816.GS08_07870	0.0	2225.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CYT7@85004|Bifidobacteriales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
AKELHBIC_01172	290340.AAur_2352	6.74e-44	157.0	COG1653@1|root,COG1653@2|Bacteria,2I3WZ@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_01173	762211.BSTEL_1538	2.76e-68	209.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	HIT
AKELHBIC_01174	762211.BSTEL_1537	1.73e-218	617.0	COG1904@1|root,COG1904@2|Bacteria,2I8PE@201174|Actinobacteria,4D085@85004|Bifidobacteriales	201174|Actinobacteria	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
AKELHBIC_01175	762211.BSTEL_1536	2.41e-241	674.0	COG0246@1|root,COG0246@2|Bacteria,2GJ4F@201174|Actinobacteria,4D0F8@85004|Bifidobacteriales	201174|Actinobacteria	G	Mannitol dehydrogenase C-terminal domain	mtlD	-	1.1.1.57,1.1.1.58	ko:K00040,ko:K00041	ko00040,ko01100,map00040,map01100	M00061,M00631	R02454,R02555	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
AKELHBIC_01176	762211.BSTEL_1535	1.82e-295	806.0	COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
AKELHBIC_01177	1437610.BREU_0418	6.66e-288	801.0	COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4CZFG@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
AKELHBIC_01178	762211.BSTEL_1539	4.05e-89	278.0	COG1609@1|root,COG1609@2|Bacteria,2GMUU@201174|Actinobacteria,4D0SY@85004|Bifidobacteriales	201174|Actinobacteria	K	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
AKELHBIC_01179	1122933.JNIY01000003_gene198	6.63e-68	223.0	COG1609@1|root,COG1609@2|Bacteria,2GMUU@201174|Actinobacteria,4F1RR@85016|Cellulomonadaceae	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
AKELHBIC_01180	1437609.BCAL_1609	9.21e-58	196.0	COG2211@1|root,COG2211@2|Bacteria,2IAMT@201174|Actinobacteria,4CZNI@85004|Bifidobacteriales	201174|Actinobacteria	G	MFS/sugar transport protein	-	-	-	ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2.5	-	-	MFS_2,Peripla_BP_3
AKELHBIC_01181	1437609.BCAL_1135	6.46e-27	109.0	COG2211@1|root,COG2211@2|Bacteria,2IAMT@201174|Actinobacteria,4CZNI@85004|Bifidobacteriales	201174|Actinobacteria	G	MFS/sugar transport protein	-	-	-	ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2.5	-	-	MFS_2,Peripla_BP_3
AKELHBIC_01183	1158606.I579_01182	2.35e-219	622.0	COG2211@1|root,COG2211@2|Bacteria,1U037@1239|Firmicutes,4HBZK@91061|Bacilli,4B4RK@81852|Enterococcaceae	91061|Bacilli	G	MFS/sugar transport protein	uxuT	-	-	ko:K03292,ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.5	-	-	MFS_2
AKELHBIC_01184	78344.BIGA_1651	3.11e-169	483.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_01185	1693.BMIN_0233	3.99e-40	141.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
AKELHBIC_01186	216816.GS08_07860	1.02e-64	204.0	COG0582@1|root,COG0582@2|Bacteria,2HUXN@201174|Actinobacteria,4CZ21@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_5,Phage_integrase
AKELHBIC_01188	1437610.BREU_0807	2.38e-77	233.0	28PY9@1|root,2ZCI0@2|Bacteria,2INBV@201174|Actinobacteria,4D13Q@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01189	1437609.BCAL_0961	3.25e-09	55.8	COG0394@1|root,COG0394@2|Bacteria,2GMPR@201174|Actinobacteria,4D0GD@85004|Bifidobacteriales	201174|Actinobacteria	T	Low molecular weight phosphatase family	etp	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
AKELHBIC_01190	158787.BSCA_1760	1.02e-29	118.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2GKW1@201174|Actinobacteria,4CYXY@85004|Bifidobacteriales	201174|Actinobacteria	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
AKELHBIC_01191	216816.GS08_07740	3.31e-57	177.0	COG0776@1|root,COG0776@2|Bacteria,2IKQR@201174|Actinobacteria,4D11V@85004|Bifidobacteriales	201174|Actinobacteria	L	Belongs to the bacterial histone-like protein family	hup	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
AKELHBIC_01192	216816.GS08_07735	0.0	1519.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4CYRT@85004|Bifidobacteriales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
AKELHBIC_01193	216816.GS08_07730	0.0	961.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4CYV6@85004|Bifidobacteriales	201174|Actinobacteria	F	Adenylosuccinate lyase C-terminal	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
AKELHBIC_01194	1479623.JHEL01000007_gene1791	4.32e-14	67.4	2DZ2S@1|root,34C82@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01195	216816.GS08_07715	0.0	1006.0	COG1075@1|root,COG1075@2|Bacteria,2IHFB@201174|Actinobacteria,4CZ17@85004|Bifidobacteriales	201174|Actinobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Abhydrolase_8,PGAP1
AKELHBIC_01196	216816.GS08_07710	7.7e-69	208.0	2B109@1|root,31TDG@2|Bacteria,2GS74@201174|Actinobacteria,4D1MD@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01197	216816.GS08_07705	1.49e-80	244.0	2BG6D@1|root,32A37@2|Bacteria,2IR67@201174|Actinobacteria,4D18W@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01198	216816.GS08_07700	7.86e-224	619.0	COG2304@1|root,COG2304@2|Bacteria,2GJMP@201174|Actinobacteria,4CZ8P@85004|Bifidobacteriales	201174|Actinobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
AKELHBIC_01199	216816.GS08_07695	3.04e-237	654.0	COG2304@1|root,COG2304@2|Bacteria,2I9VM@201174|Actinobacteria,4CZ00@85004|Bifidobacteriales	201174|Actinobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
AKELHBIC_01200	216816.GS08_07690	1.96e-112	324.0	2AUTC@1|root,31KGE@2|Bacteria,2IKRN@201174|Actinobacteria,4D134@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01201	216816.GS08_07685	1.72e-218	603.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4CYYD@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
AKELHBIC_01202	216816.GS08_07680	3.76e-246	677.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CZ2I@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
AKELHBIC_01203	216816.GS08_07675	6.65e-168	468.0	COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria,4CZ3Y@85004|Bifidobacteriales	201174|Actinobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
AKELHBIC_01204	216816.GS08_07670	1.82e-97	290.0	2DP6P@1|root,330SA@2|Bacteria,2GQYA@201174|Actinobacteria,4CZYT@85004|Bifidobacteriales	201174|Actinobacteria	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
AKELHBIC_01205	216816.GS08_07665	2.18e-51	162.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4D1FB@85004|Bifidobacteriales	201174|Actinobacteria	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
AKELHBIC_01206	216816.GS08_07660	0.0	1005.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CZJK@85004|Bifidobacteriales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
AKELHBIC_01207	216816.GS08_07655	2.78e-55	173.0	COG4842@1|root,COG4842@2|Bacteria,2GQI8@201174|Actinobacteria,4D17K@85004|Bifidobacteriales	201174|Actinobacteria	S	Proteins of 100 residues with WXG	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
AKELHBIC_01208	216816.GS08_07650	5.32e-113	329.0	2B59T@1|root,31Y3Y@2|Bacteria,2HZNR@201174|Actinobacteria,4D12Q@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
AKELHBIC_01209	216816.GS08_07645	2.26e-170	476.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CYPS@85004|Bifidobacteriales	201174|Actinobacteria	KT	Response regulator receiver domain protein	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
AKELHBIC_01210	216816.GS08_07640	0.0	1249.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4CZNF@85004|Bifidobacteriales	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
AKELHBIC_01211	216816.GS08_07635	1.01e-86	255.0	COG1278@1|root,COG1278@2|Bacteria,2IKXN@201174|Actinobacteria,4D0V4@85004|Bifidobacteriales	201174|Actinobacteria	K	'Cold-shock' DNA-binding domain	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
AKELHBIC_01212	216816.GS08_07630	3.16e-247	683.0	28NWB@1|root,2ZBU7@2|Bacteria,2GJ74@201174|Actinobacteria,4CYW9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3027)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3027
AKELHBIC_01213	216816.GS08_07595	1.43e-224	619.0	COG0589@1|root,COG0589@2|Bacteria,2IA7S@201174|Actinobacteria,4CZZ0@85004|Bifidobacteriales	201174|Actinobacteria	T	Belongs to the universal stress protein A family	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
AKELHBIC_01214	216816.GS08_07590	0.0	1587.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CZCH@85004|Bifidobacteriales	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
AKELHBIC_01215	216816.GS08_07560	0.0	1064.0	COG0737@1|root,COG0737@2|Bacteria,2GKC3@201174|Actinobacteria,4D0CZ@85004|Bifidobacteriales	201174|Actinobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
AKELHBIC_01216	216816.GS08_07555	0.0	869.0	COG3266@1|root,COG3266@2|Bacteria,2I2EC@201174|Actinobacteria,4CYYM@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
AKELHBIC_01217	216816.GS08_07550	0.0	904.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CYR9@85004|Bifidobacteriales	201174|Actinobacteria	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
AKELHBIC_01218	216816.GS08_07545	0.0	1203.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4CYWQ@85004|Bifidobacteriales	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
AKELHBIC_01220	216816.GS08_07540	3.55e-232	638.0	COG2852@1|root,COG2852@2|Bacteria,2GN40@201174|Actinobacteria,4CZJT@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
AKELHBIC_01221	1437608.BBIA_0610	2.37e-27	110.0	COG4585@1|root,COG4585@2|Bacteria,2GRUK@201174|Actinobacteria,4D1I0@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
AKELHBIC_01222	326426.Bbr_1346	1.93e-181	507.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CYXE@85004|Bifidobacteriales	201174|Actinobacteria	E	ATP-binding protein of ABC transporter for glutamate K02028	gluA	-	-	ko:K10008	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.9	-	-	ABC_tran
AKELHBIC_01223	216816.GS08_07525	2.31e-193	537.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4CZA4@85004|Bifidobacteriales	201174|Actinobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	gluB	-	-	ko:K10005	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	SBP_bac_3
AKELHBIC_01224	326426.Bbr_1344	3.05e-137	390.0	COG0765@1|root,COG0765@2|Bacteria,2GNUR@201174|Actinobacteria,4CZ5M@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	gluC	-	-	ko:K10006	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	BPD_transp_1
AKELHBIC_01225	216816.GS08_07515	2.69e-238	658.0	COG0765@1|root,COG0765@2|Bacteria,2GNBH@201174|Actinobacteria,4CZB4@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	gluD	-	-	ko:K10007	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	BPD_transp_1
AKELHBIC_01226	216816.GS08_07510	0.0	979.0	COG0671@1|root,COG0671@2|Bacteria,2I4ZG@201174|Actinobacteria,4CZ80@85004|Bifidobacteriales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
AKELHBIC_01227	216816.GS08_07505	2.51e-39	146.0	COG0737@1|root,COG3204@1|root,COG0737@2|Bacteria,COG3204@2|Bacteria,2GKC3@201174|Actinobacteria,4D03Y@85004|Bifidobacteriales	201174|Actinobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Exo_endo_phos,LTD,Metallophos
AKELHBIC_01228	216816.GS08_07495	2.88e-249	685.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4CZZU@85004|Bifidobacteriales	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
AKELHBIC_01229	216816.GS08_07490	0.0	1697.0	COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria,4CZVX@85004|Bifidobacteriales	201174|Actinobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
AKELHBIC_01230	216816.GS08_07485	1.58e-313	856.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CZ2K@85004|Bifidobacteriales	201174|Actinobacteria	L	Recombination factor protein RarA	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
AKELHBIC_01231	216816.GS08_07445	0.0	868.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZ0R@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
AKELHBIC_01232	216816.GS08_07440	9.11e-236	648.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4CZUN@85004|Bifidobacteriales	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
AKELHBIC_01233	216816.GS08_07435	1.48e-106	313.0	COG2314@1|root,COG2314@2|Bacteria,2IQB3@201174|Actinobacteria,4D11Z@85004|Bifidobacteriales	201174|Actinobacteria	J	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
AKELHBIC_01234	216816.GS08_07430	8.24e-71	214.0	COG1950@1|root,COG1950@2|Bacteria,2HZND@201174|Actinobacteria,4D117@85004|Bifidobacteriales	201174|Actinobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
AKELHBIC_01235	216816.GS08_07425	3.84e-62	191.0	COG1534@1|root,COG1534@2|Bacteria,2IKSS@201174|Actinobacteria,4D10K@85004|Bifidobacteriales	201174|Actinobacteria	J	CRS1_YhbY	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
AKELHBIC_01236	216816.GS08_07420	0.0	1428.0	COG0619@1|root,COG1129@1|root,COG0619@2|Bacteria,COG1129@2|Bacteria,2I2G4@201174|Actinobacteria,4CZJE@85004|Bifidobacteriales	201174|Actinobacteria	GP	ABC transporter, ATP-binding protein	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ
AKELHBIC_01237	216816.GS08_07415	5.79e-138	392.0	COG3601@1|root,COG3601@2|Bacteria,2IAX0@201174|Actinobacteria,4CZQD@85004|Bifidobacteriales	201174|Actinobacteria	U	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
AKELHBIC_01238	216816.GS08_07410	1.82e-257	704.0	COG1216@1|root,COG1216@2|Bacteria,2GMQQ@201174|Actinobacteria,4CZRJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
AKELHBIC_01239	216816.GS08_07405	1.56e-179	500.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4CYR1@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
AKELHBIC_01240	216816.GS08_07400	7.89e-288	788.0	COG0436@1|root,COG0436@2|Bacteria,2GNMB@201174|Actinobacteria,4CZ48@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
AKELHBIC_01241	216816.GS08_07395	9.84e-178	496.0	COG1122@1|root,COG1122@2|Bacteria,2I9PF@201174|Actinobacteria,4D04S@85004|Bifidobacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16784	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25.1	-	-	ABC_tran
AKELHBIC_01242	216816.GS08_07390	0.0	1403.0	COG1807@1|root,COG1807@2|Bacteria,2GNXR@201174|Actinobacteria,4CZXK@85004|Bifidobacteriales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01243	216816.GS08_07385	0.0	2265.0	COG0457@1|root,COG0457@2|Bacteria,2GWSR@201174|Actinobacteria,4CZ33@85004|Bifidobacteriales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
AKELHBIC_01244	216816.GS08_07380	0.0	1796.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4CZBC@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
AKELHBIC_01245	216816.GS08_07375	1.91e-259	712.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,2GJUZ@201174|Actinobacteria,4CZDC@85004|Bifidobacteriales	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	GO:0008150,GO:0040007	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
AKELHBIC_01246	216816.GS08_07345	0.0	1120.0	COG3525@1|root,COG3525@2|Bacteria,2HZCI@201174|Actinobacteria,4CZS1@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
AKELHBIC_01247	216816.GS08_07310	2.21e-162	457.0	COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,4CYRQ@85004|Bifidobacteriales	201174|Actinobacteria	V	Uncharacterised protein family (UPF0014)	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
AKELHBIC_01248	216816.GS08_07305	2.16e-145	413.0	COG1136@1|root,COG1136@2|Bacteria,2I8QP@201174|Actinobacteria,4CZZG@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
AKELHBIC_01249	216816.GS08_07300	7.09e-136	384.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CYY6@85004|Bifidobacteriales	201174|Actinobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
AKELHBIC_01250	216816.GS08_07295	1.42e-121	348.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4D0WG@85004|Bifidobacteriales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
AKELHBIC_01251	216816.GS08_07290	6.07e-303	827.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4CYQ1@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
AKELHBIC_01252	216816.GS08_07285	0.0	2209.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CZJ4@85004|Bifidobacteriales	201174|Actinobacteria	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
AKELHBIC_01253	216816.GS08_07280	4.92e-213	589.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4D2UX@85004|Bifidobacteriales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
AKELHBIC_01254	216816.GS08_07275	3.08e-134	380.0	COG0194@1|root,COG0194@2|Bacteria,2I2FT@201174|Actinobacteria,4CYUT@85004|Bifidobacteriales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
AKELHBIC_01256	216816.GS08_07270	3.69e-168	469.0	COG2176@1|root,COG2176@2|Bacteria,2I2FU@201174|Actinobacteria,4D10C@85004|Bifidobacteriales	201174|Actinobacteria	L	Exonuclease, DNA polymerase III, epsilon subunit family	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T
AKELHBIC_01257	216816.GS08_07265	0.0	1491.0	COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria,4CZM5@85004|Bifidobacteriales	201174|Actinobacteria	J	Elongation factor G, domain IV	tetM	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
AKELHBIC_01258	216816.GS08_07260	3.71e-154	432.0	COG0400@1|root,COG0400@2|Bacteria,2I5NR@201174|Actinobacteria,4CZJQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
AKELHBIC_01259	566552.BIFCAT_01772	5.83e-125	359.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4CZ8E@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	glnP2	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
AKELHBIC_01260	518635.BIFANG_02430	7.57e-142	402.0	COG0765@1|root,COG0765@2|Bacteria,2GN44@201174|Actinobacteria,4CZG7@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	glnP	-	-	ko:K02029,ko:K10040	ko02010,map02010	M00228,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
AKELHBIC_01261	401473.BDP_0689	3.79e-145	414.0	COG1126@1|root,COG1126@2|Bacteria,2H1ZM@201174|Actinobacteria,4CZTK@85004|Bifidobacteriales	201174|Actinobacteria	E	ATP binding protein of ABC transporter for glutamate aspartate K02028	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
AKELHBIC_01262	566552.BIFCAT_01775	2.34e-167	473.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4CZAC@85004|Bifidobacteriales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	glnH	-	-	ko:K02030,ko:K10039	ko02010,map02010	M00228,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
AKELHBIC_01263	216816.GS08_07255	1.35e-283	776.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CZKK@85004|Bifidobacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metC1	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
AKELHBIC_01264	216816.GS08_07250	2.28e-57	177.0	COG0695@1|root,COG0695@2|Bacteria,2HZQB@201174|Actinobacteria,4D18H@85004|Bifidobacteriales	201174|Actinobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
AKELHBIC_01265	216816.GS08_07245	1.16e-198	549.0	COG0346@1|root,COG0346@2|Bacteria,2IH7I@201174|Actinobacteria,4D0TJ@85004|Bifidobacteriales	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
AKELHBIC_01266	216816.GS08_07240	1.33e-186	519.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4CZK0@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
AKELHBIC_01267	216816.GS08_07235	1.82e-256	702.0	COG0407@1|root,COG0407@2|Bacteria,2IBXM@201174|Actinobacteria,4D067@85004|Bifidobacteriales	201174|Actinobacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
AKELHBIC_01268	216816.GS08_07230	5.91e-280	765.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CZYU@85004|Bifidobacteriales	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
AKELHBIC_01269	216816.GS08_07225	0.0	1114.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4D2SK@85004|Bifidobacteriales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
AKELHBIC_01270	216816.GS08_07220	0.0	1163.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GKSQ@201174|Actinobacteria,4CZE0@85004|Bifidobacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
AKELHBIC_01271	216816.GS08_07215	1.27e-292	798.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4D053@85004|Bifidobacteriales	201174|Actinobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
AKELHBIC_01272	216816.GS08_07210	1.05e-309	844.0	COG2873@1|root,COG2873@2|Bacteria,2I8JG@201174|Actinobacteria,4CZ6W@85004|Bifidobacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
AKELHBIC_01273	216816.GS08_07205	2.79e-176	491.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4D0CN@85004|Bifidobacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	ehuA	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
AKELHBIC_01274	216816.GS08_07200	4.62e-184	513.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4D0FX@85004|Bifidobacteriales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
AKELHBIC_01275	216816.GS08_07195	2.37e-143	405.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4CZIX@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	tcyA/tcyB	-	-	ko:K02029,ko:K02424,ko:K10009	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1,SBP_bac_3
AKELHBIC_01276	216816.GS08_07190	5.79e-173	488.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CYTU@85004|Bifidobacteriales	201174|Actinobacteria	O	prohibitin homologues	hflK	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
AKELHBIC_01277	216816.GS08_02610	1.41e-266	729.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_01278	1089455.MOPEL_088_00010	2.65e-76	260.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
AKELHBIC_01279	762051.LKI_03390	2.32e-22	97.1	COG0531@1|root,COG0531@2|Bacteria,1TPVA@1239|Firmicutes,4HAWC@91061|Bacilli,4AXM6@81850|Leuconostocaceae	91061|Bacilli	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
AKELHBIC_01280	1423743.JCM14108_3151	3.98e-26	110.0	COG0531@1|root,COG0531@2|Bacteria,1TPVA@1239|Firmicutes,4HAWC@91061|Bacilli,3F56G@33958|Lactobacillaceae	91061|Bacilli	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
AKELHBIC_01281	78346.BRUM_0133	3.83e-247	682.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01284	216816.GS08_07185	2.32e-199	552.0	COG4667@1|root,COG4667@2|Bacteria,2I8R7@201174|Actinobacteria,4CZUH@85004|Bifidobacteriales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
AKELHBIC_01285	216816.GS08_07180	1.83e-187	521.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CZ54@85004|Bifidobacteriales	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
AKELHBIC_01286	216816.GS08_07175	1.48e-214	592.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4CYQP@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
AKELHBIC_01287	216816.GS08_07170	1.04e-163	459.0	COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria,4CZN1@85004|Bifidobacteriales	201174|Actinobacteria	S	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
AKELHBIC_01288	216816.GS08_07165	1.87e-217	599.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4CYQ5@85004|Bifidobacteriales	201174|Actinobacteria	S	DNA polymerase alpha chain like domain	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
AKELHBIC_01289	216816.GS08_07160	1.13e-44	144.0	2AS45@1|root,31HGW@2|Bacteria,2HZSD@201174|Actinobacteria,4D1H9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
AKELHBIC_01290	216816.GS08_07155	0.0	1032.0	COG3173@1|root,COG3173@2|Bacteria,2I8R6@201174|Actinobacteria,4CYPR@85004|Bifidobacteriales	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	mphA	-	-	-	-	-	-	-	-	-	-	-	APH
AKELHBIC_01291	216816.GS08_07150	0.0	1004.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4CZ3A@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA helicase	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
AKELHBIC_01292	216816.GS08_07145	0.0	1090.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria,4CYU7@85004|Bifidobacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
AKELHBIC_01293	216816.GS08_07140	4.86e-202	560.0	COG3480@1|root,COG3480@2|Bacteria,2GMFX@201174|Actinobacteria,4CYUP@85004|Bifidobacteriales	201174|Actinobacteria	T	Belongs to the peptidase S16 family	sdrC	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C
AKELHBIC_01294	216816.GS08_07135	2.15e-65	202.0	2B57P@1|root,31Y1M@2|Bacteria,2IFRB@201174|Actinobacteria,4D307@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3052)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
AKELHBIC_01296	216816.GS08_07120	0.0	959.0	COG3170@1|root,COG3170@2|Bacteria,2I2GE@201174|Actinobacteria,4CZDF@85004|Bifidobacteriales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01297	216816.GS08_07115	5.81e-271	743.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4CZVC@85004|Bifidobacteriales	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
AKELHBIC_01298	216816.GS08_07110	2.79e-295	805.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CYQB@85004|Bifidobacteriales	201174|Actinobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
AKELHBIC_01299	216816.GS08_07105	0.0	974.0	COG0657@1|root,COG0657@2|Bacteria,2I2GD@201174|Actinobacteria,4CZUD@85004|Bifidobacteriales	201174|Actinobacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01300	216816.GS08_07100	7.4e-145	411.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CZCN@85004|Bifidobacteriales	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
AKELHBIC_01301	216816.GS08_07095	4.53e-196	542.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CZAR@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.86,2.5.1.88	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	-	R06447,R09244,R09731	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
AKELHBIC_01302	1437610.BREU_0334	5.54e-265	728.0	COG1957@1|root,COG1957@2|Bacteria,2I9SG@201174|Actinobacteria,4CZWE@85004|Bifidobacteriales	201174|Actinobacteria	F	nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
AKELHBIC_01303	216816.GS08_07085	9.84e-261	714.0	COG0715@1|root,COG0715@2|Bacteria,2HZ9T@201174|Actinobacteria,4CZ56@85004|Bifidobacteriales	201174|Actinobacteria	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
AKELHBIC_01304	216816.GS08_07080	2.67e-178	497.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4CZ9Q@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
AKELHBIC_01305	326426.Bbr_1324	0.0	1039.0	COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria,4CZ8W@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 32 family	fosC	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
AKELHBIC_01306	401473.BDP_1602	1.8e-306	837.0	COG2807@1|root,COG2807@2|Bacteria,2GJRD@201174|Actinobacteria,4CYTK@85004|Bifidobacteriales	201174|Actinobacteria	P	LacY proton/sugar symporter	lacY	-	-	ko:K02532	-	-	-	-	ko00000,ko02000	2.A.1.5	-	-	LacY_symp
AKELHBIC_01307	216816.GS08_07060	2.17e-243	669.0	COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria,4CYU5@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
AKELHBIC_01308	326426.Bbr_1320	0.0	913.0	COG4826@1|root,COG4826@2|Bacteria,2GJ5T@201174|Actinobacteria,4D0C1@85004|Bifidobacteriales	201174|Actinobacteria	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
AKELHBIC_01309	216816.GS08_07050	4.43e-24	100.0	2CK5B@1|root,2ZYDK@2|Bacteria,2HU05@201174|Actinobacteria,4D0JT@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01310	216816.GS08_07040	9.95e-86	269.0	COG4585@1|root,COG4585@2|Bacteria,2I370@201174|Actinobacteria,4D0JE@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01311	216816.GS08_07030	6.69e-81	240.0	COG0011@1|root,COG0011@2|Bacteria,2IQ7E@201174|Actinobacteria,4D14E@85004|Bifidobacteriales	201174|Actinobacteria	S	Thiamine-binding protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
AKELHBIC_01312	216816.GS08_07025	6.13e-187	520.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4CYQA@85004|Bifidobacteriales	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	GO:0008150,GO:0040007	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
AKELHBIC_01313	216816.GS08_07020	1.08e-285	781.0	COG1222@1|root,COG1222@2|Bacteria,2I5C1@201174|Actinobacteria,4D0DP@85004|Bifidobacteriales	201174|Actinobacteria	O	AAA domain (Cdc48 subfamily)	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA
AKELHBIC_01314	216816.GS08_07015	0.0	1817.0	COG0352@1|root,COG0422@1|root,COG0352@2|Bacteria,COG0422@2|Bacteria,2GJ3Y@201174|Actinobacteria,4D2W5@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
AKELHBIC_01315	216816.GS08_07010	1.85e-212	588.0	COG2145@1|root,COG2145@2|Bacteria,2IC73@201174|Actinobacteria,4CZU8@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
AKELHBIC_01316	216816.GS08_07005	0.0	1025.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CYZU@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
AKELHBIC_01317	326426.Bbr_1304	6.49e-306	833.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4CZFD@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
AKELHBIC_01318	216816.GS08_06995	1.5e-259	714.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CZ10@85004|Bifidobacteriales	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
AKELHBIC_01319	216816.GS08_06990	2.78e-103	299.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4D0RJ@85004|Bifidobacteriales	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
AKELHBIC_01320	216816.GS08_06985	3.18e-56	176.0	COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria,4D17B@85004|Bifidobacteriales	201174|Actinobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
AKELHBIC_01321	216816.GS08_06980	6.92e-142	421.0	COG1566@1|root,COG1566@2|Bacteria,2I2G9@201174|Actinobacteria,4CZ5W@85004|Bifidobacteriales	201174|Actinobacteria	V	DivIVA protein	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
AKELHBIC_01322	216816.GS08_06975	3.64e-117	336.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4D0WR@85004|Bifidobacteriales	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
AKELHBIC_01323	216816.GS08_06970	2.49e-229	631.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CYYR@85004|Bifidobacteriales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
AKELHBIC_01324	1680.BADO_1353	6.62e-31	122.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01325	1437610.BREU_0220	1.13e-22	107.0	COG4585@1|root,COG4585@2|Bacteria,2IKQ3@201174|Actinobacteria,4D15W@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
AKELHBIC_01326	401473.BDP_2017	4.78e-38	139.0	COG2197@1|root,COG2197@2|Bacteria,2IQKB@201174|Actinobacteria,4D1A1@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
AKELHBIC_01327	698964.CDPW8_2179	2.31e-21	92.4	2EP87@1|root,31XYZ@2|Bacteria,2GZXP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01329	566552.BIFCAT_01291	3.92e-162	461.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4CZHQ@85004|Bifidobacteriales	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
AKELHBIC_01330	326426.Bbr_0312	2.37e-274	754.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D01G@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01331	216816.GS08_06965	2.63e-164	463.0	COG1295@1|root,COG1295@2|Bacteria,2GN79@201174|Actinobacteria,4CZM4@85004|Bifidobacteriales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
AKELHBIC_01332	216816.GS08_06960	0.0	2366.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CZKT@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA polymerase III alpha subunit	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
AKELHBIC_01333	216816.GS08_06955	9.06e-99	286.0	2DMJC@1|root,32RYJ@2|Bacteria,2IHZV@201174|Actinobacteria,4D0UY@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4186)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4186
AKELHBIC_01334	216816.GS08_06950	0.0	1298.0	COG4716@1|root,COG4716@2|Bacteria,2GKZ8@201174|Actinobacteria,4CYZK@85004|Bifidobacteriales	201174|Actinobacteria	S	MCRA family	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
AKELHBIC_01335	445975.COLSTE_02537	1.09e-36	142.0	2AHMW@1|root,317ZU@2|Bacteria,2HC22@201174|Actinobacteria	201174|Actinobacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01336	216816.GS08_06925	9.11e-198	548.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CZ1F@85004|Bifidobacteriales	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
AKELHBIC_01337	216816.GS08_06920	0.0	924.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4D2SW@85004|Bifidobacteriales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
AKELHBIC_01338	216816.GS08_06915	0.0	882.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4CZ3E@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1599	Histidinol_dh
AKELHBIC_01339	216816.GS08_06910	9.06e-279	762.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4CZDT@85004|Bifidobacteriales	201174|Actinobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
AKELHBIC_01340	216816.GS08_06905	6.75e-144	405.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4CZDD@85004|Bifidobacteriales	201174|Actinobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
AKELHBIC_01341	216816.GS08_06900	2.21e-140	402.0	2EKCN@1|root,33E2Y@2|Bacteria,2GNIC@201174|Actinobacteria,4D0B5@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01342	216816.GS08_06895	6.18e-157	439.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4CZGA@85004|Bifidobacteriales	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
AKELHBIC_01343	216816.GS08_06890	4.81e-167	467.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4CZEA@85004|Bifidobacteriales	201174|Actinobacteria	E	Histidine biosynthesis protein	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
AKELHBIC_01344	216816.GS08_06885	9.93e-26	104.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4CZIY@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
AKELHBIC_01345	216816.GS08_06880	0.0	912.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CZ0G@85004|Bifidobacteriales	201174|Actinobacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
AKELHBIC_01346	216816.GS08_06875	3.48e-243	673.0	COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4CZH1@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K18567,ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.25,2.A.1.2.65	-	-	MFS_1,Sugar_tr
AKELHBIC_01347	158787.BSCA_1773	4.13e-187	523.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4D071@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	appC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
AKELHBIC_01348	158787.BSCA_1774	3.79e-226	624.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4D0MU@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
AKELHBIC_01349	158787.BSCA_1775	0.0	1080.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,4D09J@85004|Bifidobacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
AKELHBIC_01350	158787.BSCA_1776	0.0	1058.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CYU0@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
AKELHBIC_01351	158787.BSCA_1777	9.21e-221	610.0	COG5479@1|root,COG5479@2|Bacteria,2HYIN@201174|Actinobacteria,4CYU1@85004|Bifidobacteriales	201174|Actinobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01352	216816.GS08_06830	0.0	2638.0	COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,4CZ3C@85004|Bifidobacteriales	201174|Actinobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
AKELHBIC_01353	216816.GS08_06825	3.86e-157	440.0	COG2813@1|root,COG2813@2|Bacteria,2IFG7@201174|Actinobacteria,4CZP1@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	rsmC	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
AKELHBIC_01354	216816.GS08_06820	0.0	944.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CZCB@85004|Bifidobacteriales	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
AKELHBIC_01355	216816.GS08_06815	4.62e-225	620.0	COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria,4CYWK@85004|Bifidobacteriales	201174|Actinobacteria	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
AKELHBIC_01356	216816.GS08_06810	6.04e-201	559.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4CZAB@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
AKELHBIC_01357	216816.GS08_06805	2.78e-166	465.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CZ26@85004|Bifidobacteriales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
AKELHBIC_01358	216816.GS08_06800	2.11e-48	155.0	COG1388@1|root,COG1388@2|Bacteria,2HVH4@201174|Actinobacteria,4D1G8@85004|Bifidobacteriales	201174|Actinobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
AKELHBIC_01359	216816.GS08_06795	4.7e-101	293.0	COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4D0P7@85004|Bifidobacteriales	201174|Actinobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
AKELHBIC_01360	216816.GS08_06790	1.31e-289	790.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CYPT@85004|Bifidobacteriales	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
AKELHBIC_01361	216816.GS08_06785	0.0	1466.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4CYUF@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2,Viral_helicase1
AKELHBIC_01362	216816.GS08_06780	3.86e-119	340.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4D0P1@85004|Bifidobacteriales	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
AKELHBIC_01363	216816.GS08_06775	9.64e-249	684.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CYRM@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
AKELHBIC_01364	216816.GS08_06770	2.74e-96	281.0	COG2919@1|root,COG2919@2|Bacteria,2IKUA@201174|Actinobacteria,4D109@85004|Bifidobacteriales	201174|Actinobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01365	216816.GS08_06765	0.0	1150.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CYS8@85004|Bifidobacteriales	201174|Actinobacteria	M	Penicillin-binding protein, transpeptidase domain protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
AKELHBIC_01366	216816.GS08_06760	6.85e-196	544.0	COG0769@1|root,COG0769@2|Bacteria,2GMZF@201174|Actinobacteria,4CYWT@85004|Bifidobacteriales	201174|Actinobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01367	216816.GS08_06755	0.0	889.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CZ7U@85004|Bifidobacteriales	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
AKELHBIC_01368	216816.GS08_06750	7.84e-264	723.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CYRX@85004|Bifidobacteriales	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
AKELHBIC_01369	216816.GS08_06745	0.0	945.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CZKI@85004|Bifidobacteriales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2155c	AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M
AKELHBIC_01370	216816.GS08_06740	6.74e-286	781.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4CYPZ@85004|Bifidobacteriales	201174|Actinobacteria	D	Belongs to the SEDS family	ftsW	GO:0008150,GO:0040007	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
AKELHBIC_01371	216816.GS08_06735	5.46e-279	763.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4CYQS@85004|Bifidobacteriales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	-	R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
AKELHBIC_01372	216816.GS08_06730	0.0	984.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4CZ3B@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
AKELHBIC_01373	216816.GS08_06725	9.32e-233	643.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4D04A@85004|Bifidobacteriales	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
AKELHBIC_01375	398513.BBNG_00723	4.49e-101	302.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZUB@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	tnp3521a2	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
AKELHBIC_01376	883069.HMPREF9238_01632	3.04e-138	399.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4D63Y@85005|Actinomycetales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_01377	883069.HMPREF9238_01633	2.98e-109	321.0	COG0842@1|root,COG0842@2|Bacteria,2HM0S@201174|Actinobacteria,4D65M@85005|Actinomycetales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
AKELHBIC_01378	883069.HMPREF9238_01634	2.95e-37	144.0	COG1944@1|root,COG1944@2|Bacteria,2GKBS@201174|Actinobacteria	201174|Actinobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
AKELHBIC_01379	883069.HMPREF9238_01634	6.1e-85	273.0	COG1944@1|root,COG1944@2|Bacteria,2GKBS@201174|Actinobacteria	201174|Actinobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
AKELHBIC_01381	1120933.ATUY01000001_gene945	2.88e-34	121.0	2AU29@1|root,31JNG@2|Bacteria,2IJMS@201174|Actinobacteria,4D5T5@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01383	216816.GS08_06710	1.76e-57	178.0	COG3636@1|root,COG3636@2|Bacteria,2IRAI@201174|Actinobacteria,4D1DK@85004|Bifidobacteriales	201174|Actinobacteria	K	Addiction module	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01384	1002804.HBZC1_18030	4.31e-13	64.7	COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,42V2I@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	TIGRFAM Addiction module killer protein	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
AKELHBIC_01385	216816.GS08_06700	6.47e-64	195.0	2AZUG@1|root,31S3T@2|Bacteria,2GQ7F@201174|Actinobacteria,4D1BR@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01386	216816.GS08_06695	1.95e-109	315.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4D0VE@85004|Bifidobacteriales	201174|Actinobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
AKELHBIC_01387	326426.Bbr_1150	0.0	2020.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4CYWB@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
AKELHBIC_01388	216816.GS08_06685	0.0	1934.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4CYWB@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
AKELHBIC_01389	216816.GS08_06600	0.0	905.0	COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria,4D2RC@85004|Bifidobacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
AKELHBIC_01390	518635.BIFANG_02623	3.78e-221	614.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CZSV@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
AKELHBIC_01391	216816.GS08_06590	2.67e-230	640.0	COG1173@1|root,COG1173@2|Bacteria,2GKAW@201174|Actinobacteria,4CZ2Y@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
AKELHBIC_01392	216816.GS08_06585	0.0	1026.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CYU0@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
AKELHBIC_01393	216816.GS08_06645	2.03e-212	593.0	COG1609@1|root,COG1609@2|Bacteria,2GJHF@201174|Actinobacteria,4CZCC@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
AKELHBIC_01394	216816.GS08_06640	1.62e-296	809.0	COG2942@1|root,COG2942@2|Bacteria,2GMJ7@201174|Actinobacteria,4CZNY@85004|Bifidobacteriales	201174|Actinobacteria	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
AKELHBIC_01395	326426.Bbr_1139	0.0	887.0	COG3538@1|root,COG3538@2|Bacteria,2HHAF@201174|Actinobacteria,4CZYN@85004|Bifidobacteriales	201174|Actinobacteria	S	Metal-independent alpha-mannosidase (GH125)	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
AKELHBIC_01396	216816.GS08_06630	4.97e-218	601.0	COG0524@1|root,COG0524@2|Bacteria,2HZB3@201174|Actinobacteria,4CZFC@85004|Bifidobacteriales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
AKELHBIC_01397	216816.GS08_06625	1.57e-279	765.0	COG1940@1|root,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4CYV9@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,MarR_2,ROK
AKELHBIC_01398	216816.GS08_06620	9.11e-208	575.0	COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria,4CZII@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
AKELHBIC_01399	216816.GS08_06615	6.36e-257	706.0	COG1940@1|root,COG1940@2|Bacteria,2GKMZ@201174|Actinobacteria,4CZUF@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	Crp,ROK
AKELHBIC_01400	216816.GS08_06610	3.16e-191	531.0	COG0363@1|root,COG0363@2|Bacteria,2GK7F@201174|Actinobacteria,4CYYE@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
AKELHBIC_01401	216816.GS08_06605	1.02e-293	803.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4CZKB@85004|Bifidobacteriales	201174|Actinobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
AKELHBIC_01402	1341695.BBOMB_1153	1.11e-254	706.0	COG1653@1|root,COG1653@2|Bacteria,2HZAD@201174|Actinobacteria,4CZ9S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_01403	1341695.BBOMB_1154	1.18e-139	403.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZQU@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
AKELHBIC_01404	1341695.BBOMB_1155	1.83e-158	451.0	COG0395@1|root,COG0395@2|Bacteria,2I8S0@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AKELHBIC_01406	398513.BBNG_00491	1.47e-98	288.0	COG1051@1|root,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria,4CZS4@85004|Bifidobacteriales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
AKELHBIC_01407	216816.GS08_06575	0.0	1037.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CZIA@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminopeptidase P, N-terminal domain	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
AKELHBIC_01408	216816.GS08_06570	1.3e-202	563.0	COG5340@1|root,COG5340@2|Bacteria,2ICPH@201174|Actinobacteria,4CZJ7@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01409	216816.GS08_06565	0.0	1013.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CZG9@85004|Bifidobacteriales	201174|Actinobacteria	H	Mur ligase middle domain	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2447c	Mur_ligase_C,Mur_ligase_M
AKELHBIC_01410	216816.GS08_06560	0.0	2039.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CZ8Q@85004|Bifidobacteriales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
AKELHBIC_01411	216816.GS08_06555	5.54e-243	667.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4CZT9@85004|Bifidobacteriales	201174|Actinobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
AKELHBIC_01412	216816.GS08_06550	0.0	1014.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CZAF@85004|Bifidobacteriales	201174|Actinobacteria	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
AKELHBIC_01413	216816.GS08_06545	9.69e-166	465.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CZ09@85004|Bifidobacteriales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
AKELHBIC_01414	216816.GS08_06540	6.7e-72	216.0	29M53@1|root,3082I@2|Bacteria,2GTWX@201174|Actinobacteria,4D1EJ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01415	216816.GS08_06535	3.18e-238	653.0	COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria,4CYWN@85004|Bifidobacteriales	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
AKELHBIC_01416	216816.GS08_06530	2.97e-245	671.0	COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria,4CYWN@85004|Bifidobacteriales	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
AKELHBIC_01417	216816.GS08_06525	1.43e-229	633.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CZ8B@85004|Bifidobacteriales	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
AKELHBIC_01418	216816.GS08_06430	1.3e-115	331.0	COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria,4CZFI@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
AKELHBIC_01419	216816.GS08_06425	1.05e-253	696.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CZ97@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
AKELHBIC_01420	216816.GS08_06420	7.74e-173	482.0	COG1564@1|root,COG1564@2|Bacteria,2HQZZ@201174|Actinobacteria,4CZBY@85004|Bifidobacteriales	201174|Actinobacteria	H	Thiamin pyrophosphokinase, vitamin B1 binding domain	-	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
AKELHBIC_01421	216816.GS08_06415	3.43e-111	323.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CZA3@85004|Bifidobacteriales	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
AKELHBIC_01422	216816.GS08_06410	1.4e-36	123.0	COG0291@1|root,COG0291@2|Bacteria,2HZRM@201174|Actinobacteria,4D1EV@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
AKELHBIC_01423	216816.GS08_06405	9.07e-80	237.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4D0QF@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
AKELHBIC_01424	326426.Bbr_1227	8.54e-240	663.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4CZRH@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
AKELHBIC_01425	326426.Bbr_1226	1.35e-183	514.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZ69@85004|Bifidobacteriales	201174|Actinobacteria	D	recombinase XerD	xerD	GO:0008150,GO:0040007	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
AKELHBIC_01426	216816.GS08_06395	9.42e-192	535.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CYV4@85004|Bifidobacteriales	201174|Actinobacteria	D	CobQ CobB MinD ParA nucleotide binding domain protein	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
AKELHBIC_01427	216816.GS08_06390	5.17e-198	551.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4CYRV@85004|Bifidobacteriales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
AKELHBIC_01428	216816.GS08_06385	2.34e-152	430.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4D0QW@85004|Bifidobacteriales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
AKELHBIC_01429	216816.GS08_06380	7.49e-197	545.0	COG1051@1|root,COG1051@2|Bacteria,2GNMT@201174|Actinobacteria,4CZNZ@85004|Bifidobacteriales	201174|Actinobacteria	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
AKELHBIC_01430	216816.GS08_06375	0.0	866.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,4D0AI@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
AKELHBIC_01431	216816.GS08_06370	0.0	1036.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4D01P@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	GO:0008150,GO:0040007	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1595	FAD_binding_2,Succ_DH_flav_C
AKELHBIC_01432	216816.GS08_06365	5.3e-208	575.0	COG0157@1|root,COG0157@2|Bacteria,2GV9P@201174|Actinobacteria,4CZWA@85004|Bifidobacteriales	201174|Actinobacteria	H	Quinolinate phosphoribosyl transferase, N-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
AKELHBIC_01433	216816.GS08_06360	2.78e-274	753.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4CZVW@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class-V	iscS1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
AKELHBIC_01434	216816.GS08_06335	0.0	1258.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CYX3@85004|Bifidobacteriales	201174|Actinobacteria	T	Elongation factor G C-terminus	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
AKELHBIC_01436	1437609.BCAL_0608	1.01e-09	61.6	COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria,4D2TR@85004|Bifidobacteriales	201174|Actinobacteria	K	Divergent AAA domain protein	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
AKELHBIC_01437	216816.GS08_06330	2.17e-97	283.0	2E9EF@1|root,333MW@2|Bacteria,2IKWQ@201174|Actinobacteria,4D10T@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01438	216816.GS08_06325	9.17e-245	671.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CZ61@85004|Bifidobacteriales	201174|Actinobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
AKELHBIC_01439	216816.GS08_06320	7.95e-250	686.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CYV2@85004|Bifidobacteriales	201174|Actinobacteria	E	Prephenate dehydrogenase	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
AKELHBIC_01440	216816.GS08_06315	3.75e-57	177.0	2BGJ3@1|root,32AHC@2|Bacteria,2IR91@201174|Actinobacteria,4D17H@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01441	216816.GS08_06310	6.93e-239	658.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZCX@85004|Bifidobacteriales	201174|Actinobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
AKELHBIC_01442	216816.GS08_06305	0.0	1077.0	COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales	201174|Actinobacteria	E	ABC transporter, substrate-binding protein, family 5	dppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
AKELHBIC_01443	216816.GS08_06300	1.55e-201	560.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CZSV@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	dppB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
AKELHBIC_01444	326426.Bbr_1203	1.28e-229	633.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CYQF@85004|Bifidobacteriales	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	dppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
AKELHBIC_01445	216816.GS08_06290	0.0	1277.0	COG0444@1|root,COG1123@1|root,COG0444@2|Bacteria,COG4172@2|Bacteria,2GIXV@201174|Actinobacteria,4D2V0@85004|Bifidobacteriales	201174|Actinobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
AKELHBIC_01446	216816.GS08_06285	1.08e-215	594.0	COG0708@1|root,COG0708@2|Bacteria,2GKIS@201174|Actinobacteria,4CYVB@85004|Bifidobacteriales	201174|Actinobacteria	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
AKELHBIC_01447	216816.GS08_06280	8.7e-196	543.0	28J4D@1|root,30NZ9@2|Bacteria,2I2E9@201174|Actinobacteria,4D2VD@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3710)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3710
AKELHBIC_01448	216816.GS08_06275	1.87e-173	485.0	2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,4CYQX@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159
AKELHBIC_01449	216816.GS08_06270	2.87e-307	837.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4CYYN@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
AKELHBIC_01450	216816.GS08_06265	2.54e-148	419.0	2AVVG@1|root,31MP9@2|Bacteria,2INFG@201174|Actinobacteria,4D12J@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
AKELHBIC_01451	216816.GS08_06260	0.0	1463.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CYS1@85004|Bifidobacteriales	201174|Actinobacteria	P	E1-E2 ATPase	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
AKELHBIC_01452	216816.GS08_06255	0.0	1801.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4CZ3T@85004|Bifidobacteriales	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
AKELHBIC_01453	216816.GS08_06250	2.89e-75	225.0	COG3077@1|root,COG3077@2|Bacteria,2IT2R@201174|Actinobacteria,4D175@85004|Bifidobacteriales	201174|Actinobacteria	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
AKELHBIC_01454	216816.GS08_06245	6.28e-111	319.0	COG2402@1|root,COG2402@2|Bacteria,2I5GT@201174|Actinobacteria,4D2B6@85004|Bifidobacteriales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
AKELHBIC_01455	216816.GS08_06240	0.0	1396.0	COG1479@1|root,COG1479@2|Bacteria,2I99F@201174|Actinobacteria,4CZ4G@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
AKELHBIC_01456	216816.GS08_06235	3.2e-152	427.0	COG1246@1|root,COG1246@2|Bacteria,2I61X@201174|Actinobacteria,4D2U1@85004|Bifidobacteriales	201174|Actinobacteria	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
AKELHBIC_01457	216816.GS08_06225	1.51e-188	526.0	COG0670@1|root,COG0670@2|Bacteria,2I98Y@201174|Actinobacteria,4CZIJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
AKELHBIC_01458	216816.GS08_06220	2.85e-220	610.0	COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria,4D0BH@85004|Bifidobacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
AKELHBIC_01459	216816.GS08_06215	1.9e-174	488.0	COG2357@1|root,COG2357@2|Bacteria,2GKF8@201174|Actinobacteria,4CYXP@85004|Bifidobacteriales	201174|Actinobacteria	S	Region found in RelA / SpoT proteins	ywaC	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
AKELHBIC_01460	1693.BMIN_1095	2.51e-218	610.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01464	1035195.HMPREF9997_01927	6.2e-08	58.2	COG0452@1|root,COG0452@2|Bacteria,2HTRU@201174|Actinobacteria,22R4N@1653|Corynebacteriaceae	201174|Actinobacteria	H	Flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavoprotein
AKELHBIC_01467	1096756.ATKN01000019_gene1552	4.47e-76	257.0	COG0488@1|root,COG0488@2|Bacteria,2GJHN@201174|Actinobacteria,1WB68@1268|Micrococcaceae	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
AKELHBIC_01468	1437608.BBIA_0616	2.6e-256	707.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_01469	1437610.BREU_2323	1.83e-97	294.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4D0M5@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
AKELHBIC_01470	1437610.BREU_2323	2.41e-113	336.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4D0M5@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
AKELHBIC_01471	216816.GS08_06210	0.0	952.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CZFB@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
AKELHBIC_01472	216816.GS08_06205	1.51e-234	645.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CZNS@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
AKELHBIC_01473	216816.GS08_06200	5.81e-177	493.0	COG2184@1|root,COG2184@2|Bacteria,2IN0D@201174|Actinobacteria,4D03T@85004|Bifidobacteriales	201174|Actinobacteria	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Fic
AKELHBIC_01474	216816.GS08_06195	0.0	1800.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CZ5T@85004|Bifidobacteriales	201174|Actinobacteria	D	FtsK SpoIIIE family protein	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
AKELHBIC_01475	216816.GS08_06190	9.72e-151	424.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CZ36@85004|Bifidobacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
AKELHBIC_01476	216816.GS08_06185	1.83e-119	342.0	COG1546@1|root,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4D0CM@85004|Bifidobacteriales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
AKELHBIC_01477	216816.GS08_06180	1.06e-106	309.0	COG1426@1|root,COG1426@2|Bacteria,2I2G5@201174|Actinobacteria,4D0PT@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
AKELHBIC_01478	216816.GS08_06175	4.64e-52	163.0	2EFU9@1|root,339KE@2|Bacteria,2GQJW@201174|Actinobacteria,4D16T@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3046)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3046
AKELHBIC_01479	216816.GS08_06170	3.4e-259	713.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CYYY@85004|Bifidobacteriales	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
AKELHBIC_01480	216816.GS08_06165	2.52e-129	368.0	COG2137@1|root,COG2137@2|Bacteria,2INKM@201174|Actinobacteria,4D0Y4@85004|Bifidobacteriales	201174|Actinobacteria	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
AKELHBIC_01481	216816.GS08_06160	1.43e-144	409.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CZ3H@85004|Bifidobacteriales	201174|Actinobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
AKELHBIC_01482	216816.GS08_06155	0.0	1824.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4CYX6@85004|Bifidobacteriales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
AKELHBIC_01483	1437608.BBIA_0938	1.68e-83	253.0	COG2755@1|root,COG2755@2|Bacteria,2IDIX@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
AKELHBIC_01484	158787.BSCA_1512	2.13e-219	608.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4CZKZ@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
AKELHBIC_01485	326426.Bbr_1176	3.27e-108	317.0	2AP35@1|root,31E4N@2|Bacteria,2IBUY@201174|Actinobacteria,4D0R7@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01486	216816.GS08_06120	1.56e-166	465.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4CZBB@85004|Bifidobacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
AKELHBIC_01487	216816.GS08_06115	0.0	1369.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CYTR@85004|Bifidobacteriales	201174|Actinobacteria	KLT	PASTA	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
AKELHBIC_01488	216816.GS08_06110	2.35e-245	675.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4CZQV@85004|Bifidobacteriales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
AKELHBIC_01489	216816.GS08_06105	2.71e-158	443.0	2B5AP@1|root,31Y4U@2|Bacteria,2IF9M@201174|Actinobacteria,4D15J@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4192
AKELHBIC_01490	216816.GS08_06100	1.19e-242	677.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CZQC@85004|Bifidobacteriales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
AKELHBIC_01491	216816.GS08_06095	0.0	1482.0	COG0187@1|root,COG0187@2|Bacteria,2GM1E@201174|Actinobacteria,4CYXR@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA topoisomerase (ATP-hydrolyzing)	gyrB2	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
AKELHBIC_01492	216816.GS08_06090	3.87e-266	732.0	COG0738@1|root,COG0738@2|Bacteria,2HWKN@201174|Actinobacteria,4CYRZ@85004|Bifidobacteriales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_01493	216816.GS08_06085	3.03e-102	305.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CZIB@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
AKELHBIC_01494	216816.GS08_06080	0.0	3055.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4D01F@85004|Bifidobacteriales	201174|Actinobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
AKELHBIC_01495	216816.GS08_06075	4.17e-167	469.0	COG0745@1|root,COG0745@2|Bacteria,2ISFD@201174|Actinobacteria,4D188@85004|Bifidobacteriales	201174|Actinobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
AKELHBIC_01496	216816.GS08_06070	0.0	1717.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CYVH@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA topoisomerase (ATP-hydrolyzing)	gyrA2	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
AKELHBIC_01497	216816.GS08_06065	1.43e-296	810.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,4CZCK@85004|Bifidobacteriales	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
AKELHBIC_01498	216816.GS08_06060	7.13e-237	654.0	29W72@1|root,30HS9@2|Bacteria,2HZB4@201174|Actinobacteria,4CZFJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3071
AKELHBIC_01499	216816.GS08_06055	1.42e-62	191.0	2ATJW@1|root,3361K@2|Bacteria,2I80Y@201174|Actinobacteria,4D10Y@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4193)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4193
AKELHBIC_01500	326426.Bbr_1158	3.4e-108	311.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CZUJ@85004|Bifidobacteriales	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
AKELHBIC_01501	216816.GS08_06045	0.0	1511.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CZCW@85004|Bifidobacteriales	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
AKELHBIC_01502	216816.GS08_06040	5.15e-132	375.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4CZSU@85004|Bifidobacteriales	201174|Actinobacteria	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
AKELHBIC_01504	216816.GS08_06030	6.02e-37	124.0	COG1476@1|root,COG1476@2|Bacteria,2GQIU@201174|Actinobacteria,4D1HQ@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
AKELHBIC_01505	78344.BIGA_1648	2.61e-269	742.0	COG2801@1|root,COG2801@2|Bacteria,2I8Z0@201174|Actinobacteria,4D0BU@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_01506	216816.GS08_06025	2.63e-36	122.0	2B0NT@1|root,31T0I@2|Bacteria,2GRGK@201174|Actinobacteria,4D1EC@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01507	216816.GS08_06020	2.27e-54	176.0	COG2184@1|root,COG2184@2|Bacteria,2IN0D@201174|Actinobacteria,4D03T@85004|Bifidobacteriales	201174|Actinobacteria	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Fic
AKELHBIC_01508	78344.BIGA_1648	2.14e-268	739.0	COG2801@1|root,COG2801@2|Bacteria,2I8Z0@201174|Actinobacteria,4D0BU@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_01509	216816.GS08_06000	5.35e-305	832.0	COG0477@1|root,COG2814@2|Bacteria,2I8QF@201174|Actinobacteria,4CZF1@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
AKELHBIC_01510	216816.GS08_05995	4.64e-61	188.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
AKELHBIC_01511	216816.GS08_05950	7.91e-91	270.0	COG3415@1|root,COG3415@2|Bacteria,2IQ1N@201174|Actinobacteria,4D14Z@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01512	216816.GS08_05945	1.47e-78	235.0	COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,rve,rve_2
AKELHBIC_01513	216816.GS08_05975	9.48e-237	650.0	COG4823@1|root,COG4823@2|Bacteria,2HWAP@201174|Actinobacteria,4D0Z3@85004|Bifidobacteriales	201174|Actinobacteria	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
AKELHBIC_01515	216816.GS08_05970	1.31e-98	285.0	2ATF2@1|root,31IYI@2|Bacteria,2IIKG@201174|Actinobacteria,4D0ZG@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01517	326426.Bbr_1154	1.5e-312	852.0	COG3550@1|root,COG3550@2|Bacteria,2IEM1@201174|Actinobacteria,4CZPH@85004|Bifidobacteriales	201174|Actinobacteria	S	HipA-like C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HipA_C
AKELHBIC_01518	216816.GS08_05955	4.18e-201	556.0	COG3177@1|root,COG3177@2|Bacteria,2ICFW@201174|Actinobacteria,4D01T@85004|Bifidobacteriales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
AKELHBIC_01521	356829.BITS_1882	1.66e-10	62.8	2B29P@1|root,31UTG@2|Bacteria,2GUFB@201174|Actinobacteria,4D1HY@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01523	326426.Bbr_0312	5.56e-273	751.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D01G@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01524	525254.HMPREF0072_1942	7e-134	381.0	COG1136@1|root,COG1136@2|Bacteria,1V3NN@1239|Firmicutes,24I94@186801|Clostridia,22HGS@1570339|Peptoniphilaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_01525	525254.HMPREF0072_1944	1.53e-212	605.0	COG4652@1|root,COG4652@2|Bacteria,1UYA7@1239|Firmicutes,250QA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01526	401473.BDP_1440	6.64e-34	126.0	COG0842@1|root,COG0842@2|Bacteria,2H9HW@201174|Actinobacteria,4CZ1J@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
AKELHBIC_01527	332101.JIBU02000012_gene1073	5.19e-114	335.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,36DP9@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter ATP-binding	mutF	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
AKELHBIC_01528	1235798.C817_02684	2.31e-77	241.0	COG4200@1|root,COG4200@2|Bacteria,1V78D@1239|Firmicutes,25D9T@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	mutE	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
AKELHBIC_01529	1121115.AXVN01000067_gene3467	1.41e-70	223.0	COG4200@1|root,COG4200@2|Bacteria,1V4AY@1239|Firmicutes,24EXR@186801|Clostridia,3Y0KJ@572511|Blautia	186801|Clostridia	S	Lantibiotic protection ABC transporter permease subunit, MutG family	mutG	-	-	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
AKELHBIC_01530	1232447.BAHW02000002_gene32	4.56e-113	333.0	28JBR@1|root,2Z96E@2|Bacteria,1V0A1@1239|Firmicutes,24D16@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K20489	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	-
AKELHBIC_01531	1232447.BAHW02000002_gene31	6.85e-127	364.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,26APR@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
AKELHBIC_01532	411459.RUMOBE_02511	5.37e-145	427.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,3Y01W@572511|Blautia	186801|Clostridia	T	subtilin biosynthesis sensor protein SpaK	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
AKELHBIC_01533	216816.GS08_05935	2.17e-129	380.0	2E39G@1|root,32Y91@2|Bacteria,2IMAD@201174|Actinobacteria,4D0XM@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01534	216816.GS08_05930	6.21e-214	592.0	COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria,4D011@85004|Bifidobacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
AKELHBIC_01535	216816.GS08_05925	2.86e-93	272.0	COG3576@1|root,COG3576@2|Bacteria,2IJK2@201174|Actinobacteria,4D0W8@85004|Bifidobacteriales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	pdxH	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
AKELHBIC_01536	216816.GS08_05920	2.21e-312	851.0	COG0742@1|root,COG0742@2|Bacteria,2HZAY@201174|Actinobacteria,4CZEU@85004|Bifidobacteriales	201174|Actinobacteria	L	ribosomal rna small subunit methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95,Methyltransf_15,PCMT
AKELHBIC_01537	216816.GS08_05915	5.33e-209	577.0	COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4CZI8@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	gpmB	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	3.1.3.85,5.4.2.11	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
AKELHBIC_01538	216816.GS08_05910	1.42e-217	601.0	COG0598@1|root,COG0598@2|Bacteria,2HZ8V@201174|Actinobacteria,4CYWX@85004|Bifidobacteriales	201174|Actinobacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
AKELHBIC_01539	216816.GS08_05905	3.24e-192	535.0	COG0834@1|root,COG0834@2|Bacteria,2I9PU@201174|Actinobacteria,4D09U@85004|Bifidobacteriales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K10005	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	SBP_bac_3
AKELHBIC_01540	216816.GS08_05900	0.0	2025.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CZHV@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
AKELHBIC_01541	216816.GS08_05895	1.82e-99	293.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4D176@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
AKELHBIC_01542	216816.GS08_05890	0.0	961.0	COG0658@1|root,COG0658@2|Bacteria,2GJGR@201174|Actinobacteria,4CZ6X@85004|Bifidobacteriales	201174|Actinobacteria	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
AKELHBIC_01543	216816.GS08_05885	7.1e-226	623.0	COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,4CZ07@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
AKELHBIC_01544	216816.GS08_05880	9.29e-132	374.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4D0PH@85004|Bifidobacteriales	201174|Actinobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
AKELHBIC_01545	216816.GS08_05875	3.03e-190	528.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,4D0A2@85004|Bifidobacteriales	201174|Actinobacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
AKELHBIC_01546	216816.GS08_05870	3.74e-128	365.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,4D0Q0@85004|Bifidobacteriales	201174|Actinobacteria	K	FR47-like protein	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
AKELHBIC_01547	326426.Bbr_1123	7.64e-249	683.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CZ0K@85004|Bifidobacteriales	201174|Actinobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
AKELHBIC_01549	1437609.BCAL_0561	3.67e-154	444.0	2AQRU@1|root,31FZM@2|Bacteria,2IABZ@201174|Actinobacteria,4D0HM@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01550	1437609.BCAL_0562	2.26e-124	361.0	2BM4R@1|root,32FN7@2|Bacteria,2HZNA@201174|Actinobacteria,4D0ZT@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative amidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6
AKELHBIC_01551	1437610.BREU_2146	1.51e-174	495.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_01552	326426.Bbr_1114	0.0	956.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_01553	326426.Bbr_1115	8.64e-179	498.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales	201174|Actinobacteria	L	IstB-like ATP binding protein	istB	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
AKELHBIC_01554	1437610.BREU_2146	9.93e-46	157.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_01555	78346.BRUM_1693	1.92e-210	592.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4D0H8@85004|Bifidobacteriales	201174|Actinobacteria	K	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HTH_3,HTH_31,Transposase_20
AKELHBIC_01556	762211.BSTEL_0161	1.39e-26	103.0	COG5658@1|root,COG5658@2|Bacteria,2GWJG@201174|Actinobacteria,4D1RC@85004|Bifidobacteriales	201174|Actinobacteria	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
AKELHBIC_01559	1122994.AUFR01000044_gene440	7.01e-33	127.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,Fer4_12,Fer4_14,Radical_SAM,SPASM
AKELHBIC_01561	991905.SL003B_2116	4.14e-34	137.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	2.1.1.303	ko:K20421	ko01059,ko01130,map01059,map01130	M00830	R10963	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	MTS
AKELHBIC_01562	435830.HMPREF0045_01141	4.06e-51	175.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	-	ko:K18996,ko:K19171	-	-	-	-	ko00000,ko02048,ko03032	-	-	-	ABC_membrane,ABC_tran,RP-C,RP-C_C,Trans_reg_C
AKELHBIC_01563	1437609.BCAL_0563	1.54e-86	270.0	COG3505@1|root,COG3505@2|Bacteria,2HZ9D@201174|Actinobacteria,4CZ1V@85004|Bifidobacteriales	201174|Actinobacteria	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
AKELHBIC_01564	641146.HMPREF9020_01339	1.4e-26	104.0	COG0582@1|root,COG4974@1|root,COG0582@2|Bacteria,COG4974@2|Bacteria,2IH6A@201174|Actinobacteria,4CZ62@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
AKELHBIC_01568	216816.GS08_05830	9.27e-73	224.0	COG3177@1|root,COG3177@2|Bacteria,2GW8P@201174|Actinobacteria,4D1U2@85004|Bifidobacteriales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
AKELHBIC_01569	1688.BCUN_0730	1.42e-60	202.0	COG0323@1|root,COG0323@2|Bacteria,2GPWU@201174|Actinobacteria,4CZXB@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Relaxase mobilization nuclease family protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
AKELHBIC_01570	216816.GS08_05820	1.89e-253	696.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4CZMS@85004|Bifidobacteriales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K20459	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
AKELHBIC_01571	216816.GS08_05815	7.26e-181	505.0	2EIFD@1|root,33C6R@2|Bacteria,2ICFX@201174|Actinobacteria,4D0JQ@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K20460	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
AKELHBIC_01572	216816.GS08_05810	4.89e-183	511.0	2EDR0@1|root,337KK@2|Bacteria,2GM9U@201174|Actinobacteria,4D0B2@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	ko:K20461	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
AKELHBIC_01573	216816.GS08_05805	4.48e-90	266.0	28PS7@1|root,33EAY@2|Bacteria,2H508@201174|Actinobacteria,4D281@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01575	216816.GS08_05795	3.74e-302	825.0	COG4585@1|root,COG4585@2|Bacteria,2GVYN@201174|Actinobacteria,4D0I7@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,HisKA_3
AKELHBIC_01576	216816.GS08_05790	5.21e-155	436.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4D0EU@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
AKELHBIC_01579	216816.GS08_05775	1.18e-136	389.0	COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4D199@85004|Bifidobacteriales	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
AKELHBIC_01580	216816.GS08_05770	0.0	929.0	COG4213@1|root,COG4213@2|Bacteria,2HZAK@201174|Actinobacteria,4CZCR@85004|Bifidobacteriales	201174|Actinobacteria	G	ABC transporter substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
AKELHBIC_01581	216816.GS08_05765	1.35e-306	834.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria,4CZ8V@85004|Bifidobacteriales	201174|Actinobacteria	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
AKELHBIC_01582	216816.GS08_05760	6.2e-264	723.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CZDK@85004|Bifidobacteriales	201174|Actinobacteria	F	IMP dehydrogenase family protein	guaB3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
AKELHBIC_01583	326426.Bbr_1108	1.98e-91	270.0	2BGJW@1|root,32AI7@2|Bacteria,2IR97@201174|Actinobacteria,4D19G@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01584	216816.GS08_05750	0.0	1286.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYVD@85004|Bifidobacteriales	201174|Actinobacteria	I	long-chain-fatty acid CoA ligase	fadD3	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
AKELHBIC_01585	216816.GS08_05745	4.26e-113	324.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4CZ63@85004|Bifidobacteriales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
AKELHBIC_01586	216816.GS08_05740	1.37e-186	520.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CZ96@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
AKELHBIC_01587	216816.GS08_05735	2.65e-185	517.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CYVQ@85004|Bifidobacteriales	201174|Actinobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
AKELHBIC_01588	326426.Bbr_1103	4.09e-166	465.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CZEK@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
AKELHBIC_01589	216816.GS08_05725	3.22e-116	334.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CYTF@85004|Bifidobacteriales	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
AKELHBIC_01590	216816.GS08_05720	1.03e-216	600.0	COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,4CYZM@85004|Bifidobacteriales	201174|Actinobacteria	I	Cytidylyltransferase family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
AKELHBIC_01591	216816.GS08_05715	7.52e-284	775.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CZG2@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
AKELHBIC_01592	216816.GS08_05710	9.51e-97	283.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria,4D0H3@85004|Bifidobacteriales	201174|Actinobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
AKELHBIC_01593	216816.GS08_05705	5.87e-180	501.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4CZ8Z@85004|Bifidobacteriales	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007	4.1.3.27	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023,M00026	R00985,R00986,R04558	RC00010,RC01190,RC01943,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
AKELHBIC_01594	216816.GS08_05700	3.99e-92	270.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4D0WW@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1606	PRA-CH
AKELHBIC_01595	216816.GS08_05695	0.0	1015.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CZHW@85004|Bifidobacteriales	201174|Actinobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
AKELHBIC_01596	216816.GS08_05690	2.4e-145	410.0	COG2039@1|root,COG2039@2|Bacteria,2GN39@201174|Actinobacteria,4D03R@85004|Bifidobacteriales	201174|Actinobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
AKELHBIC_01597	216816.GS08_05685	3.69e-209	580.0	COG3817@1|root,COG3817@2|Bacteria,2I9GU@201174|Actinobacteria,4D0KP@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF979)	-	-	-	-	-	-	-	-	-	-	-	-	DUF979
AKELHBIC_01598	216816.GS08_05680	5.49e-153	432.0	COG3819@1|root,COG3819@2|Bacteria,2GP03@201174|Actinobacteria,4CZMP@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF969)	-	-	-	-	-	-	-	-	-	-	-	-	DUF969
AKELHBIC_01599	216816.GS08_05675	0.0	1030.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CYS2@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
AKELHBIC_01600	216816.GS08_05670	1.44e-165	463.0	COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria,4CZA7@85004|Bifidobacteriales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
AKELHBIC_01601	216816.GS08_05665	3.61e-208	575.0	COG2852@1|root,COG2852@2|Bacteria,2IGTN@201174|Actinobacteria,4D0W9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
AKELHBIC_01602	216816.GS08_05660	3.77e-46	150.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4D10G@85004|Bifidobacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
AKELHBIC_01603	1437610.BREU_0058	3.72e-23	100.0	COG1129@1|root,COG1129@2|Bacteria,2I2G1@201174|Actinobacteria,4CZ58@85004|Bifidobacteriales	201174|Actinobacteria	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
AKELHBIC_01604	1437610.BREU_0058	2.35e-24	103.0	COG1129@1|root,COG1129@2|Bacteria,2I2G1@201174|Actinobacteria,4CZ58@85004|Bifidobacteriales	201174|Actinobacteria	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
AKELHBIC_01605	1437610.BREU_0056	5.68e-19	84.3	2BY0N@1|root,321KG@2|Bacteria,2IEYW@201174|Actinobacteria,4CZZD@85004|Bifidobacteriales	201174|Actinobacteria	S	Hypothetical bacterial integral membrane protein (Trep_Strep)	-	-	-	ko:K16926	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.31	-	-	Trep_Strep
AKELHBIC_01606	1437609.BCAL_1840	7.45e-153	452.0	COG0642@1|root,COG0642@2|Bacteria,2I436@201174|Actinobacteria,4D01R@85004|Bifidobacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K18351	ko01502,ko02020,map01502,map02020	M00651,M00658	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
AKELHBIC_01607	216816.GS08_05640	1.74e-149	421.0	COG0745@1|root,COG0745@2|Bacteria,2GKYV@201174|Actinobacteria,4D0I8@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
AKELHBIC_01608	216816.GS08_05635	4.13e-188	523.0	2C1Z0@1|root,2ZDUM@2|Bacteria,2IFSE@201174|Actinobacteria,4D0QC@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01609	1437608.BBIA_0748	5.69e-188	531.0	COG3409@1|root,COG3409@2|Bacteria,2I9HW@201174|Actinobacteria,4D007@85004|Bifidobacteriales	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
AKELHBIC_01610	216816.GS08_05625	3.52e-175	489.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4D0EN@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_01611	1437608.BBIA_0746	1.46e-207	583.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4D000@85004|Bifidobacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
AKELHBIC_01612	216816.GS08_05615	0.0	1020.0	2ETEZ@1|root,33KYW@2|Bacteria,2HXGA@201174|Actinobacteria,4CZSC@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3375
AKELHBIC_01613	216816.GS08_05610	3.27e-150	423.0	2APK1@1|root,31EP8@2|Bacteria,2IEAB@201174|Actinobacteria,4D0C3@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
AKELHBIC_01614	216816.GS08_05605	0.0	2298.0	COG4913@1|root,COG4913@2|Bacteria,2GMIP@201174|Actinobacteria,4CYWR@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
AKELHBIC_01615	216816.GS08_05595	0.0	2006.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CYRU@85004|Bifidobacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
AKELHBIC_01616	216816.GS08_05590	0.0	1518.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CYVX@85004|Bifidobacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
AKELHBIC_01617	216816.GS08_05585	8.76e-236	648.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CZCM@85004|Bifidobacteriales	201174|Actinobacteria	E	Shikimate dehydrogenase substrate binding domain	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2552c	Shikimate_DH,Shikimate_dh_N
AKELHBIC_01618	216816.GS08_05580	2.61e-235	647.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4CZ70@85004|Bifidobacteriales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
AKELHBIC_01619	216816.GS08_05575	1.42e-217	601.0	COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,4CYTD@85004|Bifidobacteriales	201174|Actinobacteria	K	May be required for sporulation	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
AKELHBIC_01620	216816.GS08_05570	3.72e-281	769.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CZJ3@85004|Bifidobacteriales	201174|Actinobacteria	F	Phosphoglycerate kinase	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
AKELHBIC_01621	216816.GS08_05565	7.71e-186	517.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CYSG@85004|Bifidobacteriales	201174|Actinobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
AKELHBIC_01622	326426.Bbr_0996	2.51e-47	152.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,4D16U@85004|Bifidobacteriales	201174|Actinobacteria	U	Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
AKELHBIC_01623	216816.GS08_05555	5.61e-224	617.0	COG0039@1|root,COG0039@2|Bacteria,2IASS@201174|Actinobacteria,4CZRT@85004|Bifidobacteriales	201174|Actinobacteria	C	Belongs to the LDH MDH superfamily	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
AKELHBIC_01624	216816.GS08_05550	5.34e-210	579.0	COG0561@1|root,COG0561@2|Bacteria,2HZYB@201174|Actinobacteria,4CZQW@85004|Bifidobacteriales	201174|Actinobacteria	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
AKELHBIC_01625	1437610.BREU_0030	0.0	874.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZVJ@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase, class I II	aspC	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	iNJ661.Rv0337c	Aminotran_1_2
AKELHBIC_01626	216816.GS08_05540	5.57e-271	747.0	COG0534@1|root,COG0534@2|Bacteria,2GXXK@201174|Actinobacteria,4D04E@85004|Bifidobacteriales	201174|Actinobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AKELHBIC_01627	326426.Bbr_1001	1.17e-276	762.0	COG1114@1|root,COG1114@2|Bacteria,2GNMD@201174|Actinobacteria,4CZIP@85004|Bifidobacteriales	201174|Actinobacteria	U	Component of the transport system for branched-chain amino acids	brnQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
AKELHBIC_01628	216816.GS08_05525	3.03e-256	703.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales	201174|Actinobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
AKELHBIC_01629	216816.GS08_05520	0.0	1390.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales	201174|Actinobacteria	H	Belongs to the transketolase family	tkt	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
AKELHBIC_01630	216816.GS08_05515	4.28e-238	658.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CZK3@85004|Bifidobacteriales	201174|Actinobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
AKELHBIC_01631	216816.GS08_05510	3.8e-273	747.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4D03K@85004|Bifidobacteriales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
AKELHBIC_01632	216816.GS08_05505	1.78e-198	548.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,4CZ4W@85004|Bifidobacteriales	201174|Actinobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
AKELHBIC_01633	216816.GS08_05500	8e-197	547.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CZ83@85004|Bifidobacteriales	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
AKELHBIC_01634	216816.GS08_05495	2.11e-206	570.0	COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria,4CYSJ@85004|Bifidobacteriales	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
AKELHBIC_01640	326426.Bbr_1009	0.0	1352.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4CZD3@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
AKELHBIC_01641	326426.Bbr_1010	8.91e-142	399.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4CZS7@85004|Bifidobacteriales	201174|Actinobacteria	FG	HIT domain	-	GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
AKELHBIC_01642	326426.Bbr_1011	1.19e-156	442.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CZ9X@85004|Bifidobacteriales	201174|Actinobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
AKELHBIC_01643	326426.Bbr_1012	1.58e-126	361.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CZ79@85004|Bifidobacteriales	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
AKELHBIC_01644	216816.GS08_05445	4.97e-114	330.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CZCE@85004|Bifidobacteriales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
AKELHBIC_01645	216816.GS08_05440	3.32e-242	667.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CZGU@85004|Bifidobacteriales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
AKELHBIC_01646	216816.GS08_05435	4.71e-51	166.0	COG1862@1|root,COG1862@2|Bacteria,2IKUJ@201174|Actinobacteria,4D139@85004|Bifidobacteriales	201174|Actinobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
AKELHBIC_01647	216816.GS08_05430	5.63e-115	332.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4CZ9H@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
AKELHBIC_01648	216816.GS08_05425	1.87e-269	739.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CZCQ@85004|Bifidobacteriales	201174|Actinobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
AKELHBIC_01649	216816.GS08_05420	3.68e-202	561.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CYX1@85004|Bifidobacteriales	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
AKELHBIC_01650	216816.GS08_05415	3.26e-309	845.0	2EKVE@1|root,33EIZ@2|Bacteria,2HZ8H@201174|Actinobacteria,4CYRN@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01651	216816.GS08_05410	0.0	1067.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4CZ3P@85004|Bifidobacteriales	201174|Actinobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
AKELHBIC_01652	1437608.BBIA_1467	3.3e-41	137.0	2AXAE@1|root,31P9H@2|Bacteria,2IQKC@201174|Actinobacteria,4D18B@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3017
AKELHBIC_01653	216816.GS08_05405	1.55e-208	579.0	COG0580@1|root,COG0580@2|Bacteria,2HZ9W@201174|Actinobacteria,4CZ5Q@85004|Bifidobacteriales	201174|Actinobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
AKELHBIC_01654	216816.GS08_05400	4.49e-184	511.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4CZGG@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
AKELHBIC_01655	216816.GS08_05395	0.0	1368.0	COG0283@1|root,COG1160@1|root,COG0283@2|Bacteria,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4CYSE@85004|Bifidobacteriales	201174|Actinobacteria	F	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
AKELHBIC_01657	216816.GS08_05385	0.0	1016.0	COG4284@1|root,COG4284@2|Bacteria,2I2G3@201174|Actinobacteria,4CYTQ@85004|Bifidobacteriales	201174|Actinobacteria	G	UTP-glucose-1-phosphate uridylyltransferase	ugp	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
AKELHBIC_01658	216816.GS08_05380	0.0	1221.0	COG2378@1|root,COG2378@2|Bacteria,2I8M5@201174|Actinobacteria,4CZWF@85004|Bifidobacteriales	201174|Actinobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
AKELHBIC_01659	216816.GS08_05375	1.86e-64	197.0	2B5BE@1|root,31Y5K@2|Bacteria,2IQT5@201174|Actinobacteria,4D17A@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01660	216816.GS08_05370	0.0	1675.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4CZEC@85004|Bifidobacteriales	201174|Actinobacteria	L	DEAD DEAH box helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
AKELHBIC_01661	216816.GS08_05365	6.43e-81	239.0	2CNY9@1|root,32SI2@2|Bacteria,2IMK6@201174|Actinobacteria,4D0V5@85004|Bifidobacteriales	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RbpA
AKELHBIC_01662	216816.GS08_05360	6.36e-171	477.0	COG0546@1|root,COG0546@2|Bacteria,2HFGX@201174|Actinobacteria,4CYSF@85004|Bifidobacteriales	201174|Actinobacteria	S	HAD-hyrolase-like	nt5e	GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0071704,GO:0140096,GO:1901564	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
AKELHBIC_01663	326426.Bbr_1031	2.44e-50	159.0	2BB9R@1|root,324SH@2|Bacteria,2H9QN@201174|Actinobacteria,4D2DN@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01665	203267.TWT_175	2.34e-56	185.0	COG1136@1|root,COG1136@2|Bacteria,2GNB3@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	hrtA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_01667	644284.Arch_0526	1.86e-91	274.0	COG2197@1|root,COG2197@2|Bacteria,2GTBG@201174|Actinobacteria,4D3VJ@85005|Actinomycetales	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg,Sigma70_r4_2
AKELHBIC_01668	585199.HMPREF0577_0410	1.83e-81	261.0	COG4585@1|root,COG4585@2|Bacteria,2IJ42@201174|Actinobacteria,4D4YU@85005|Actinomycetales	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HisKA_3
AKELHBIC_01670	216816.GS08_05350	3.24e-75	227.0	29TZI@1|root,30F8H@2|Bacteria,2ISJH@201174|Actinobacteria,4D0Z6@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01671	216816.GS08_05345	6.65e-145	409.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4CZ0X@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
AKELHBIC_01672	216816.GS08_05340	1.17e-96	281.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4D0R3@85004|Bifidobacteriales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	garA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
AKELHBIC_01673	216816.GS08_05335	1.26e-178	499.0	COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria,4CYYH@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
AKELHBIC_01674	216816.GS08_05330	7.03e-51	163.0	COG3856@1|root,COG3856@2|Bacteria,2IKJW@201174|Actinobacteria,4D12G@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1290)	sbp	-	-	-	-	-	-	-	-	-	-	-	DUF1290
AKELHBIC_01675	216816.GS08_05325	1.83e-197	551.0	COG3879@1|root,COG3879@2|Bacteria,2GMS5@201174|Actinobacteria,4CZ72@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
AKELHBIC_01676	216816.GS08_05320	3.16e-136	386.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4CZGD@85004|Bifidobacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
AKELHBIC_01677	216816.GS08_05315	1.84e-201	558.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CZ66@85004|Bifidobacteriales	201174|Actinobacteria	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
AKELHBIC_01678	216816.GS08_05310	3.56e-56	174.0	COG0140@1|root,COG0140@2|Bacteria,2IQ4D@201174|Actinobacteria,4D108@85004|Bifidobacteriales	201174|Actinobacteria	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0044403,GO:0044419,GO:0044464,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0071944,GO:0075136,GO:0075139	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
AKELHBIC_01679	216816.GS08_05305	2.27e-142	403.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CYX0@85004|Bifidobacteriales	201174|Actinobacteria	G	Ribulose-phosphate 3-epimerase	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
AKELHBIC_01680	216816.GS08_05300	6.94e-238	652.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CYV8@85004|Bifidobacteriales	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	LGT
AKELHBIC_01681	326426.Bbr_1043	2.94e-206	570.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4D0A3@85004|Bifidobacteriales	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
AKELHBIC_01682	216816.GS08_05290	0.0	1355.0	COG0133@1|root,COG0134@1|root,COG0133@2|Bacteria,COG0134@2|Bacteria,2GM7Z@201174|Actinobacteria,4CZJW@85004|Bifidobacteriales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PALP
AKELHBIC_01683	326426.Bbr_1045	1.84e-170	475.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4CZPW@85004|Bifidobacteriales	201174|Actinobacteria	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
AKELHBIC_01684	216816.GS08_05280	5.06e-197	546.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4CZ0H@85004|Bifidobacteriales	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
AKELHBIC_01685	216816.GS08_05275	0.0	889.0	COG0833@1|root,COG0833@2|Bacteria,2I2DX@201174|Actinobacteria,4D2V7@85004|Bifidobacteriales	201174|Actinobacteria	E	amino acid	-	-	-	ko:K16235	-	-	-	-	ko00000,ko02000	2.A.3.1.10	-	-	AA_permease
AKELHBIC_01686	216816.GS08_05270	9.24e-106	308.0	COG0477@1|root,COG2814@2|Bacteria,2I8QF@201174|Actinobacteria,4CZF1@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
AKELHBIC_01687	326426.Bbr_1049	1.41e-239	659.0	COG4767@1|root,COG4767@2|Bacteria,2H595@201174|Actinobacteria,4CZBZ@85004|Bifidobacteriales	201174|Actinobacteria	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	RDD,VanZ
AKELHBIC_01688	749414.SBI_00921	4.69e-62	206.0	COG0520@1|root,COG0520@2|Bacteria,2GNM2@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase, class V	cefD	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
AKELHBIC_01689	326426.Bbr_1054	9.09e-33	115.0	COG4367@1|root,COG4367@2|Bacteria,2IPTA@201174|Actinobacteria,4D10S@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2316)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2316
AKELHBIC_01690	216816.GS08_05230	1.1e-129	367.0	COG3981@1|root,COG3981@2|Bacteria,2HEQC@201174|Actinobacteria,4D0EK@85004|Bifidobacteriales	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
AKELHBIC_01691	158787.BSCA_0158	3.41e-34	122.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
AKELHBIC_01692	762211.BSTEL_1667	0.0	1105.0	COG0591@1|root,COG0591@2|Bacteria,2GKPW@201174|Actinobacteria,4D21N@85004|Bifidobacteriales	201174|Actinobacteria	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
AKELHBIC_01693	762211.BSTEL_1668	9.29e-57	178.0	2C74X@1|root,305RB@2|Bacteria,2HZZ3@201174|Actinobacteria,4D2BV@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01694	216816.GS08_05225	1.06e-46	152.0	2B0WB@1|root,31T91@2|Bacteria,2GRYR@201174|Actinobacteria,4D1GV@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01695	326426.Bbr_1057	1.14e-154	436.0	arCOG08992@1|root,333S7@2|Bacteria,2IPD5@201174|Actinobacteria,4CZX8@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
AKELHBIC_01696	77635.BISU_2110	4.54e-184	521.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZ5C@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives	tnp3503b	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01697	326426.Bbr_0312	4.77e-274	754.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D01G@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01698	158787.BSCA_2269	4.5e-48	169.0	COG4585@1|root,COG4585@2|Bacteria,2GVWR@201174|Actinobacteria,4D03H@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
AKELHBIC_01699	216816.GS08_05200	5.25e-99	296.0	COG4585@1|root,COG4585@2|Bacteria,2GVWR@201174|Actinobacteria,4D03H@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
AKELHBIC_01700	326426.Bbr_1063	4.6e-31	119.0	COG0845@1|root,COG0845@2|Bacteria,2IFY7@201174|Actinobacteria,4D13B@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
AKELHBIC_01701	216816.GS08_05175	5.23e-09	57.8	COG0577@1|root,COG0577@2|Bacteria,2HXTZ@201174|Actinobacteria,4CZYZ@85004|Bifidobacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
AKELHBIC_01702	326426.Bbr_1066	3.65e-54	169.0	COG3077@1|root,COG3077@2|Bacteria,2GV25@201174|Actinobacteria,4D179@85004|Bifidobacteriales	201174|Actinobacteria	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
AKELHBIC_01703	326426.Bbr_1067	2.55e-65	198.0	COG3041@1|root,COG3041@2|Bacteria,2GSX9@201174|Actinobacteria,4D1AZ@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacterial toxin of type II toxin-antitoxin system, YafQ	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
AKELHBIC_01704	158787.BSCA_2269	3.47e-65	210.0	COG4585@1|root,COG4585@2|Bacteria,2GVWR@201174|Actinobacteria,4D03H@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
AKELHBIC_01705	326426.Bbr_1086	5.79e-41	142.0	COG0789@1|root,COG0789@2|Bacteria,2HAHU@201174|Actinobacteria,4D2NY@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01706	216816.GS08_05120	5.2e-139	394.0	2BNX6@1|root,32HM5@2|Bacteria,2GQ6P@201174|Actinobacteria,4D027@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01707	216816.GS08_05115	9.63e-61	187.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K20391	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_3,HTH_31,TPR_8
AKELHBIC_01708	216816.GS08_05075	8.82e-78	241.0	COG0477@1|root,COG0477@2|Bacteria,2I2GG@201174|Actinobacteria,4D2V3@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_01709	326426.Bbr_1090	0.0	992.0	COG0833@1|root,COG0833@2|Bacteria,2I2DX@201174|Actinobacteria,4D2V7@85004|Bifidobacteriales	201174|Actinobacteria	E	amino acid	-	-	-	ko:K16235	-	-	-	-	ko00000,ko02000	2.A.3.1.10	-	-	AA_permease
AKELHBIC_01710	326426.Bbr_1091	5.66e-13	65.1	2B5AB@1|root,31YAH@2|Bacteria,2HZT2@201174|Actinobacteria,4D1NJ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01711	78344.BIGA_1648	2.14e-268	739.0	COG2801@1|root,COG2801@2|Bacteria,2I8Z0@201174|Actinobacteria,4D0BU@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_01712	326426.Bbr_1092	1.3e-82	245.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria,4D18P@85004|Bifidobacteriales	201174|Actinobacteria	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
AKELHBIC_01713	326426.Bbr_1093	5.87e-99	287.0	2ATA8@1|root,31IT9@2|Bacteria,2IICV@201174|Actinobacteria,4D0W4@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01714	326426.Bbr_1094	8.39e-201	561.0	COG2865@1|root,COG2865@2|Bacteria,2IF0U@201174|Actinobacteria,4D0I9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01715	326426.Bbr_1095	7e-21	89.7	COG3738@1|root,COG3738@2|Bacteria,2IBMJ@201174|Actinobacteria,4CZM2@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
AKELHBIC_01717	1693.BMIN_1405	1.49e-60	199.0	COG3654@1|root,COG3943@1|root,COG3654@2|Bacteria,COG3943@2|Bacteria,2IA5J@201174|Actinobacteria,4D0WF@85004|Bifidobacteriales	201174|Actinobacteria	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
AKELHBIC_01718	216816.GS08_05005	1.34e-73	221.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria,4D18P@85004|Bifidobacteriales	201174|Actinobacteria	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
AKELHBIC_01719	216816.GS08_05000	2.88e-177	495.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4D2TF@85004|Bifidobacteriales	201174|Actinobacteria	KL	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Helicase_C,Lsr2,ResIII
AKELHBIC_01720	216816.GS08_04995	3.24e-293	799.0	COG0436@1|root,COG0436@2|Bacteria,2GPM3@201174|Actinobacteria,4CZ6T@85004|Bifidobacteriales	201174|Actinobacteria	E	Psort location Cytoplasmic, score 8.87	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
AKELHBIC_01721	216816.GS08_04990	0.0	1105.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CZC5@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
AKELHBIC_01722	216816.GS08_04985	1.85e-155	435.0	COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,4D00B@85004|Bifidobacteriales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
AKELHBIC_01723	326426.Bbr_0981	7.35e-220	606.0	COG0583@1|root,COG0583@2|Bacteria,2HZCU@201174|Actinobacteria,4CZT8@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
AKELHBIC_01724	326426.Bbr_0980	7.48e-260	713.0	COG1073@1|root,COG1073@2|Bacteria,2GMT6@201174|Actinobacteria,4CZ4Q@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974
AKELHBIC_01725	216816.GS08_04970	1.08e-39	131.0	2B3KJ@1|root,31W9X@2|Bacteria,2GWXF@201174|Actinobacteria,4D1NA@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01726	216816.GS08_04965	9.36e-160	448.0	COG0461@1|root,COG0461@2|Bacteria,2GM5A@201174|Actinobacteria,4CZHB@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
AKELHBIC_01727	216816.GS08_04960	1.98e-232	639.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CYU2@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
AKELHBIC_01728	216816.GS08_04955	4.54e-202	558.0	COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria,4CZC1@85004|Bifidobacteriales	201174|Actinobacteria	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
AKELHBIC_01729	216816.GS08_04950	4.09e-222	613.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4CZAK@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
AKELHBIC_01730	216816.GS08_04945	0.0	985.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4CZIW@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
AKELHBIC_01731	216816.GS08_04940	3.7e-96	280.0	COG1781@1|root,COG1781@2|Bacteria,2IFDF@201174|Actinobacteria,4D0QN@85004|Bifidobacteriales	201174|Actinobacteria	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
AKELHBIC_01732	216816.GS08_04935	1.18e-227	627.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CYZR@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
AKELHBIC_01733	216816.GS08_04930	0.0	2000.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4CYQE@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
AKELHBIC_01734	326426.Bbr_0971	6.95e-239	655.0	COG3049@1|root,COG3049@2|Bacteria,2GK9Z@201174|Actinobacteria,4CZNU@85004|Bifidobacteriales	201174|Actinobacteria	M	Linear amide C-N hydrolase, choloylglycine hydrolase family protein	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
AKELHBIC_01735	216816.GS08_04920	2.23e-198	550.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4CZ22@85004|Bifidobacteriales	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
AKELHBIC_01736	326426.Bbr_0969	0.0	1458.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4CYWM@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0040007,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
AKELHBIC_01737	216816.GS08_04910	6.55e-126	358.0	COG2062@1|root,COG2062@2|Bacteria,2GJ0I@201174|Actinobacteria,4D05N@85004|Bifidobacteriales	201174|Actinobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
AKELHBIC_01738	216816.GS08_04905	2.55e-247	680.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4CYUG@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
AKELHBIC_01739	326426.Bbr_0966	1.47e-120	348.0	COG0400@1|root,COG0400@2|Bacteria,2GNIF@201174|Actinobacteria,4D0TH@85004|Bifidobacteriales	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
AKELHBIC_01740	326426.Bbr_0964	1.04e-05	50.8	COG0819@1|root,COG0819@2|Bacteria,2IA0S@201174|Actinobacteria,4CZUI@85004|Bifidobacteriales	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
AKELHBIC_01741	326426.Bbr_0963	5.68e-93	279.0	COG4186@1|root,COG4186@2|Bacteria,2IRS9@201174|Actinobacteria,4D018@85004|Bifidobacteriales	201174|Actinobacteria	S	phosphoesterase or phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
AKELHBIC_01742	1437608.BBIA_0952	3.04e-28	109.0	COG4989@1|root,COG4989@2|Bacteria,2GM3C@201174|Actinobacteria,4CZZ2@85004|Bifidobacteriales	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
AKELHBIC_01743	1437608.BBIA_0952	3.75e-14	72.8	COG4989@1|root,COG4989@2|Bacteria,2GM3C@201174|Actinobacteria,4CZZ2@85004|Bifidobacteriales	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
AKELHBIC_01744	326426.Bbr_0961	9.21e-216	596.0	COG0657@1|root,COG0657@2|Bacteria,2GNKU@201174|Actinobacteria,4CZVA@85004|Bifidobacteriales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
AKELHBIC_01746	326426.Bbr_0959	2.23e-165	462.0	2EINA@1|root,33CDM@2|Bacteria,2ICYX@201174|Actinobacteria,4CZUT@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
AKELHBIC_01747	326426.Bbr_0958	5.12e-163	454.0	COG3012@1|root,COG3012@2|Bacteria,2I5YJ@201174|Actinobacteria,4D17C@85004|Bifidobacteriales	201174|Actinobacteria	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
AKELHBIC_01748	158787.BSCA_1450	2.46e-41	146.0	COG2962@1|root,COG2962@2|Bacteria,2GKCP@201174|Actinobacteria,4D0PS@85004|Bifidobacteriales	201174|Actinobacteria	S	EamA-like transporter family	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
AKELHBIC_01751	216816.GS08_04890	1.95e-22	102.0	COG0346@1|root,COG4279@1|root,COG0346@2|Bacteria,COG4279@2|Bacteria,2HZT1@201174|Actinobacteria,4D1NI@85004|Bifidobacteriales	201174|Actinobacteria	E	Rard protein	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01752	1435051.BMOU_0078	1.66e-253	725.0	COG3410@1|root,COG3410@2|Bacteria,2HNSJ@201174|Actinobacteria,4CZG3@85004|Bifidobacteriales	201174|Actinobacteria	L	Uncharacterized conserved protein (DUF2075)	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075
AKELHBIC_01753	547043.BIFPSEUDO_03874	3.01e-37	129.0	COG1694@1|root,COG1694@2|Bacteria,2IKRC@201174|Actinobacteria,4D155@85004|Bifidobacteriales	201174|Actinobacteria	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
AKELHBIC_01754	1437608.BBIA_0524	6.4e-14	71.6	COG0300@1|root,COG0300@2|Bacteria,2IIVW@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
AKELHBIC_01755	158787.BSCA_1447	1.03e-78	248.0	COG4279@1|root,COG4715@1|root,COG4279@2|Bacteria,COG4715@2|Bacteria	2|Bacteria	S	zinc ion binding	CP_1020	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
AKELHBIC_01756	326426.Bbr_0948	6.73e-179	500.0	2ARR4@1|root,31H25@2|Bacteria,2IG5G@201174|Actinobacteria,4D0U6@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01757	326426.Bbr_0947	1.26e-120	345.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4D0PN@85004|Bifidobacteriales	201174|Actinobacteria	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
AKELHBIC_01758	1680.BADO_1353	1e-71	230.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01759	1680.BADO_1353	2.81e-22	95.9	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01761	525365.HMPREF0548_1339	1.28e-119	347.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,3F56D@33958|Lactobacillaceae	91061|Bacilli	H	ThiF family	moeB	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
AKELHBIC_01762	216816.GS08_04795	5.5e-264	725.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_01765	398513.BBNG_00001	1.49e-67	209.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D1MQ@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_01766	326426.Bbr_1114	0.0	956.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_01767	326426.Bbr_1115	8.64e-179	498.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales	201174|Actinobacteria	L	IstB-like ATP binding protein	istB	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
AKELHBIC_01768	216816.GS08_07340	4.28e-22	90.5	COG2826@1|root,COG2826@2|Bacteria,2H4CW@201174|Actinobacteria,4D25Y@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
AKELHBIC_01769	1116231.SMA_1917	2.77e-67	225.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	yxaM	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_01770	1680.BADO_1353	1e-71	230.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01771	1680.BADO_1353	1.08e-37	137.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01773	216816.GS08_04780	3.6e-207	572.0	COG0561@1|root,COG0561@2|Bacteria,2GNWG@201174|Actinobacteria,4CZY9@85004|Bifidobacteriales	201174|Actinobacteria	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
AKELHBIC_01774	216816.GS08_04775	2.42e-201	557.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4CZDS@85004|Bifidobacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
AKELHBIC_01775	216816.GS08_04770	1.04e-306	835.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4CZKY@85004|Bifidobacteriales	201174|Actinobacteria	G	Starch synthase catalytic domain	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
AKELHBIC_01776	216816.GS08_04765	2.82e-105	304.0	2BI32@1|root,32C84@2|Bacteria,2IDD6@201174|Actinobacteria,4D0PC@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PsbJ
AKELHBIC_01777	216816.GS08_04760	0.0	1339.0	28J61@1|root,2Z91S@2|Bacteria,2HZIR@201174|Actinobacteria,4D0KC@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyl hydrolases related to GH101 family, GH129	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_129
AKELHBIC_01778	216816.GS08_04755	0.0	1088.0	COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales	201174|Actinobacteria	E	ABC transporter, substrate-binding protein, family 5	dppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
AKELHBIC_01779	216816.GS08_04750	0.0	1040.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4CZ7B@85004|Bifidobacteriales	201174|Actinobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3858c	Fer4_20,Pyr_redox_2
AKELHBIC_01780	216816.GS08_04745	0.0	3005.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,4CZB8@85004|Bifidobacteriales	201174|Actinobacteria	E	glutamate synthase NADPH large subunit	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
AKELHBIC_01781	216816.GS08_04715	7.3e-227	627.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4CZS8@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
AKELHBIC_01784	158787.BSCA_1948	2.18e-75	239.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4CZRH@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
AKELHBIC_01785	326426.Bbr_0932	2.36e-226	632.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4CZ81@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
AKELHBIC_01786	216816.GS08_04675	0.0	1238.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CYWI@85004|Bifidobacteriales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
AKELHBIC_01787	216816.GS08_04670	6.75e-47	151.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4D18U@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
AKELHBIC_01788	326426.Bbr_0929	2.16e-161	454.0	COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria,4CZ51@85004|Bifidobacteriales	201174|Actinobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
AKELHBIC_01789	326426.Bbr_0928	5.12e-11	62.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4CZ9U@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score 8.87	mazG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
AKELHBIC_01790	326426.Bbr_0927	2.61e-286	780.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CZD9@85004|Bifidobacteriales	201174|Actinobacteria	E	Amino-transferase class IV	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
AKELHBIC_01791	216816.GS08_04650	1.54e-112	327.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CZ7W@85004|Bifidobacteriales	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
AKELHBIC_01792	216816.GS08_04645	7.63e-248	680.0	COG1073@1|root,COG1073@2|Bacteria,2HZEB@201174|Actinobacteria,4D02D@85004|Bifidobacteriales	201174|Actinobacteria	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4
AKELHBIC_01793	216816.GS08_04640	2.57e-309	847.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4CZF5@85004|Bifidobacteriales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
AKELHBIC_01794	216816.GS08_04635	5.05e-58	180.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4D12D@85004|Bifidobacteriales	201174|Actinobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
AKELHBIC_01795	216816.GS08_04630	1.5e-257	708.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4CZZ3@85004|Bifidobacteriales	201174|Actinobacteria	C	NAD(P) transhydrogenase subunit alpha part 1 K00324	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
AKELHBIC_01796	216816.GS08_04625	0.0	1330.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYYJ@85004|Bifidobacteriales	201174|Actinobacteria	I	AMP-binding enzyme	fadD2	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
AKELHBIC_01797	216816.GS08_04620	1.32e-232	642.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CYZH@85004|Bifidobacteriales	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
AKELHBIC_01798	216816.GS08_04615	0.0	870.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4CZ1W@85004|Bifidobacteriales	201174|Actinobacteria	S	CBS domain	corC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
AKELHBIC_01799	216816.GS08_04610	1.44e-132	375.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4CZJF@85004|Bifidobacteriales	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
AKELHBIC_01800	216816.GS08_04605	4.59e-270	740.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CZJH@85004|Bifidobacteriales	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
AKELHBIC_01801	216816.GS08_04600	9.63e-77	228.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4D130@85004|Bifidobacteriales	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
AKELHBIC_01802	216816.GS08_04595	3.82e-185	515.0	COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,4CZAD@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
AKELHBIC_01804	216816.GS08_04585	1.25e-208	577.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4CYQ6@85004|Bifidobacteriales	201174|Actinobacteria	J	SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
AKELHBIC_01805	216816.GS08_04580	5.12e-306	833.0	COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4CZ4E@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
AKELHBIC_01806	216816.GS08_04575	1e-144	407.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4CYRH@85004|Bifidobacteriales	201174|Actinobacteria	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
AKELHBIC_01807	216816.GS08_04570	1.18e-132	375.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4CZU5@85004|Bifidobacteriales	201174|Actinobacteria	C	SUF system FeS assembly protein, NifU family	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
AKELHBIC_01808	216816.GS08_04565	1.46e-301	823.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CZIU@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
AKELHBIC_01809	216816.GS08_04560	3.98e-184	512.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CZU1@85004|Bifidobacteriales	201174|Actinobacteria	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
AKELHBIC_01810	216816.GS08_04555	3.57e-300	818.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CZEE@85004|Bifidobacteriales	201174|Actinobacteria	O	FeS assembly protein SufD	sufD	GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
AKELHBIC_01811	216816.GS08_04550	0.0	1005.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CZPQ@85004|Bifidobacteriales	201174|Actinobacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
AKELHBIC_01812	216816.GS08_04545	0.0	1109.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CYWE@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1699	CTP_synth_N,GATase
AKELHBIC_01813	216816.GS08_04540	2.09e-104	301.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4D0Q6@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
AKELHBIC_01814	216816.GS08_04535	0.0	1069.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2GIUZ@201174|Actinobacteria,4CZ2G@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
AKELHBIC_01815	216816.GS08_04530	3.16e-279	764.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CZ43@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
AKELHBIC_01816	216816.GS08_04525	8.73e-101	293.0	2B59B@1|root,31Y3G@2|Bacteria,2GRM1@201174|Actinobacteria,4D110@85004|Bifidobacteriales	201174|Actinobacteria	S	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
AKELHBIC_01817	216816.GS08_04520	1.92e-263	724.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CZID@85004|Bifidobacteriales	201174|Actinobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
AKELHBIC_01818	216816.GS08_04515	2.61e-102	296.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4D0WQ@85004|Bifidobacteriales	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
AKELHBIC_01819	216816.GS08_04510	0.0	1745.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CZQN@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
AKELHBIC_01820	216816.GS08_04505	2.29e-48	154.0	2B9VR@1|root,3238X@2|Bacteria,2IQYT@201174|Actinobacteria,4D16I@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01821	216816.GS08_04500	3.5e-84	249.0	COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria,4D0VH@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
AKELHBIC_01822	326426.Bbr_0895	1.84e-161	452.0	COG0406@1|root,COG0406@2|Bacteria,2GK2I@201174|Actinobacteria,4CZH2@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
AKELHBIC_01823	398513.BBNG_00001	2.63e-39	134.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D1MQ@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_01824	326426.Bbr_0894	1.48e-64	196.0	COG3077@1|root,COG3077@2|Bacteria,2GRAY@201174|Actinobacteria,4D1J9@85004|Bifidobacteriales	201174|Actinobacteria	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
AKELHBIC_01825	216816.GS08_04480	2.05e-83	246.0	COG2337@1|root,COG2337@2|Bacteria,2GZTW@201174|Actinobacteria,4D25G@85004|Bifidobacteriales	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
AKELHBIC_01826	216816.GS08_04475	1.03e-143	405.0	COG1305@1|root,COG1305@2|Bacteria,2GM42@201174|Actinobacteria,4D0N1@85004|Bifidobacteriales	201174|Actinobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
AKELHBIC_01827	326426.Bbr_0891	3.53e-66	202.0	COG5658@1|root,COG5658@2|Bacteria,2GWJG@201174|Actinobacteria,4D1RC@85004|Bifidobacteriales	201174|Actinobacteria	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
AKELHBIC_01828	216816.GS08_04465	1.43e-115	330.0	COG0295@1|root,COG0295@2|Bacteria,2IMXP@201174|Actinobacteria,4D1XM@85004|Bifidobacteriales	201174|Actinobacteria	F	cytidine deaminase activity	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
AKELHBIC_01829	326426.Bbr_0889	3.43e-190	527.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4D043@85004|Bifidobacteriales	201174|Actinobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
AKELHBIC_01830	216816.GS08_04455	1.29e-141	400.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CYSP@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
AKELHBIC_01831	216816.GS08_04450	5.15e-195	545.0	COG1136@1|root,COG1136@2|Bacteria,2IATV@201174|Actinobacteria,4CZMH@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_01832	216816.GS08_04445	5.8e-271	744.0	COG0577@1|root,COG0577@2|Bacteria,2H8C2@201174|Actinobacteria,4CZB5@85004|Bifidobacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
AKELHBIC_01833	216816.GS08_04440	3.5e-84	249.0	2CBVU@1|root,3324G@2|Bacteria,2IKKE@201174|Actinobacteria,4D106@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4418)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4418
AKELHBIC_01834	216816.GS08_04435	0.0	1559.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CYRJ@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
AKELHBIC_01835	216816.GS08_04430	5.78e-133	377.0	COG0503@1|root,COG0503@2|Bacteria,2GJ3S@201174|Actinobacteria,4CYSZ@85004|Bifidobacteriales	201174|Actinobacteria	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
AKELHBIC_01836	326426.Bbr_0882	2.75e-303	830.0	COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4CZ9F@85004|Bifidobacteriales	201174|Actinobacteria	F	Permease family	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
AKELHBIC_01837	216816.GS08_04420	6.32e-42	137.0	COG3655@1|root,COG3655@2|Bacteria,2GQZM@201174|Actinobacteria,4D1EQ@85004|Bifidobacteriales	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
AKELHBIC_01838	326426.Bbr_0880	1.11e-54	171.0	2B2KB@1|root,31V5N@2|Bacteria,2GV1B@201174|Actinobacteria,4D1EE@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
AKELHBIC_01839	216816.GS08_04410	1.25e-203	562.0	COG2267@1|root,COG2267@2|Bacteria,2GNRY@201174|Actinobacteria,4D02B@85004|Bifidobacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
AKELHBIC_01840	216816.GS08_04405	1.92e-213	590.0	COG0791@1|root,COG0791@2|Bacteria,2I38D@201174|Actinobacteria,4D2XJ@85004|Bifidobacteriales	201174|Actinobacteria	M	pfam nlp p60	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01841	216816.GS08_04400	4.58e-94	274.0	COG0346@1|root,COG0346@2|Bacteria,2II51@201174|Actinobacteria,4D0XJ@85004|Bifidobacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
AKELHBIC_01842	216816.GS08_04395	5.73e-143	403.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4CYTT@85004|Bifidobacteriales	201174|Actinobacteria	Q	Isochorismatase family	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
AKELHBIC_01843	216816.GS08_04390	2.62e-145	409.0	COG3340@1|root,COG3340@2|Bacteria,2GN35@201174|Actinobacteria,4D10R@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase family S51	pepE	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
AKELHBIC_01844	326426.Bbr_0875	3.53e-261	719.0	2CGVZ@1|root,33209@2|Bacteria,2IEU5@201174|Actinobacteria,4CZAJ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01845	158787.BSCA_0879	1.05e-135	391.0	2BE5B@1|root,327W0@2|Bacteria,2GP1A@201174|Actinobacteria,4CZYK@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01846	158787.BSCA_1372	1.08e-29	111.0	COG2755@1|root,COG2755@2|Bacteria,2IPPH@201174|Actinobacteria,4D0X0@85004|Bifidobacteriales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
AKELHBIC_01847	158787.BSCA_1372	2.69e-31	117.0	COG2755@1|root,COG2755@2|Bacteria,2IPPH@201174|Actinobacteria,4D0X0@85004|Bifidobacteriales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
AKELHBIC_01848	158787.BSCA_1372	3.2e-42	145.0	COG2755@1|root,COG2755@2|Bacteria,2IPPH@201174|Actinobacteria,4D0X0@85004|Bifidobacteriales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
AKELHBIC_01849	216816.GS08_04370	3.15e-115	331.0	COG3311@1|root,COG3311@2|Bacteria,2IQFY@201174|Actinobacteria,4D15C@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
AKELHBIC_01850	216816.GS08_04365	5.01e-124	354.0	COG1569@1|root,COG1569@2|Bacteria,2IMP1@201174|Actinobacteria,4D13G@85004|Bifidobacteriales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
AKELHBIC_01851	398513.BBNG_00718	0.0	980.0	COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria,4CYSX@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_24,HTH_5
AKELHBIC_01852	216816.GS08_04355	0.0	868.0	COG0842@1|root,COG0842@2|Bacteria,2H9HW@201174|Actinobacteria,4CZ1J@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
AKELHBIC_01853	216816.GS08_04350	7.02e-287	785.0	COG0842@1|root,COG0842@2|Bacteria,2IBJP@201174|Actinobacteria,4CZD5@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
AKELHBIC_01854	326426.Bbr_0870	2.52e-237	652.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CYUQ@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
AKELHBIC_01855	158787.BSCA_2234	2.12e-14	71.6	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4D20B@85004|Bifidobacteriales	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
AKELHBIC_01856	216816.GS08_04335	1.26e-288	792.0	COG4585@1|root,COG4585@2|Bacteria,2I9G4@201174|Actinobacteria,4CZHY@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
AKELHBIC_01857	216816.GS08_04330	8.58e-140	396.0	COG2197@1|root,COG2197@2|Bacteria,2IBZ9@201174|Actinobacteria,4D07J@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
AKELHBIC_01858	216816.GS08_04325	1.58e-146	412.0	COG1392@1|root,COG1392@2|Bacteria,2HNQ5@201174|Actinobacteria,4CZVQ@85004|Bifidobacteriales	201174|Actinobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
AKELHBIC_01859	216816.GS08_04320	2.33e-240	662.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4CZM7@85004|Bifidobacteriales	201174|Actinobacteria	P	Phosphate transporter family	pitB	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	iNJ661.Rv2281	PHO4
AKELHBIC_01860	216816.GS08_04315	0.0	897.0	COG0366@1|root,COG0366@2|Bacteria,2GJUT@201174|Actinobacteria,4D075@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha amylase, catalytic domain	nplT	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
AKELHBIC_01861	216816.GS08_04310	5.45e-08	52.8	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D0BX@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_01862	216816.GS08_04310	4.01e-07	56.2	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D0BX@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_01863	216816.GS08_04305	0.0	1290.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CZ4K@85004|Bifidobacteriales	201174|Actinobacteria	JKL	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
AKELHBIC_01864	216816.GS08_04300	4.34e-297	812.0	COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4CZR8@85004|Bifidobacteriales	201174|Actinobacteria	F	Permease family	rutG	-	-	ko:K02824,ko:K03458	-	-	-	-	ko00000,ko02000	2.A.40,2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
AKELHBIC_01865	326426.Bbr_0861	2.09e-208	575.0	COG0406@1|root,COG0406@2|Bacteria,2GN7B@201174|Actinobacteria,4CZFM@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
AKELHBIC_01866	326426.Bbr_0860	7.32e-136	384.0	COG0560@1|root,COG0560@2|Bacteria,2GMVR@201174|Actinobacteria,4D0CF@85004|Bifidobacteriales	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
AKELHBIC_01867	326426.Bbr_0859	1.31e-302	828.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4D02G@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1,MFS_3
AKELHBIC_01869	326426.Bbr_0857	8.96e-79	234.0	COG0346@1|root,COG0346@2|Bacteria,2II51@201174|Actinobacteria,4D0V7@85004|Bifidobacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
AKELHBIC_01870	566552.BIFCAT_01933	3.22e-168	473.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,4CZ65@85004|Bifidobacteriales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
AKELHBIC_01873	1680.BADO_0644	1.5e-47	153.0	COG1918@1|root,COG1918@2|Bacteria,2GS42@201174|Actinobacteria,4D1FW@85004|Bifidobacteriales	201174|Actinobacteria	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
AKELHBIC_01874	216816.GS08_04245	0.0	1238.0	COG0477@1|root,COG0517@1|root,COG0517@2|Bacteria,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales	201174|Actinobacteria	U	Drug resistance MFS transporter, drug H antiporter-2 family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MFS_1
AKELHBIC_01875	547043.BIFPSEUDO_04438	1.1e-16	72.0	29G83@1|root,3035W@2|Bacteria,2GQWW@201174|Actinobacteria,4D1G9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01876	216816.GS08_04235	3.48e-153	431.0	COG1309@1|root,COG1309@2|Bacteria,2HZJX@201174|Actinobacteria,4D0QJ@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
AKELHBIC_01877	216816.GS08_04230	1.8e-274	754.0	COG2271@1|root,COG2271@2|Bacteria,2HZ9S@201174|Actinobacteria,4CZ4Z@85004|Bifidobacteriales	201174|Actinobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_01878	326426.Bbr_0830	3.1e-309	842.0	COG3550@1|root,COG3550@2|Bacteria,2IEMD@201174|Actinobacteria,4CZ2C@85004|Bifidobacteriales	201174|Actinobacteria	S	HipA-like C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HipA_C
AKELHBIC_01879	216816.GS08_04220	1.03e-50	160.0	COG3077@1|root,COG3077@2|Bacteria,2IRS1@201174|Actinobacteria,4D1BV@85004|Bifidobacteriales	201174|Actinobacteria	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
AKELHBIC_01880	326426.Bbr_0828	1.64e-68	207.0	COG2337@1|root,COG2337@2|Bacteria,2IICB@201174|Actinobacteria,4D102@85004|Bifidobacteriales	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
AKELHBIC_01881	326426.Bbr_0827	1.67e-110	321.0	COG1917@1|root,COG1917@2|Bacteria,2IHSV@201174|Actinobacteria,4D0ZF@85004|Bifidobacteriales	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
AKELHBIC_01882	326426.Bbr_0826	6.44e-205	567.0	COG0030@1|root,COG0030@2|Bacteria,2I2II@201174|Actinobacteria,4CZIK@85004|Bifidobacteriales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
AKELHBIC_01883	216816.GS08_04200	1.35e-79	238.0	COG3304@1|root,COG3304@2|Bacteria,2IKS5@201174|Actinobacteria,4D11K@85004|Bifidobacteriales	201174|Actinobacteria	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
AKELHBIC_01884	216816.GS08_04195	7.47e-298	813.0	COG1510@1|root,COG3177@1|root,COG1510@2|Bacteria,COG3177@2|Bacteria,2HZGJ@201174|Actinobacteria,4D0D3@85004|Bifidobacteriales	201174|Actinobacteria	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
AKELHBIC_01885	216816.GS08_00995	4.19e-32	122.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZTH@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_01886	326426.Bbr_0822	0.0	1482.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CYXB@85004|Bifidobacteriales	201174|Actinobacteria	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
AKELHBIC_01887	326426.Bbr_0821	1.82e-311	851.0	COG0534@1|root,COG0534@2|Bacteria,2GXXK@201174|Actinobacteria,4D04E@85004|Bifidobacteriales	201174|Actinobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AKELHBIC_01889	326426.Bbr_0820	4.15e-39	131.0	COG3743@1|root,COG3743@2|Bacteria	2|Bacteria	S	rRNA binding	-	-	-	ko:K02890,ko:K07343	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	TfoX_C
AKELHBIC_01890	326426.Bbr_0819	2.63e-207	573.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,2GVAR@201174|Actinobacteria	201174|Actinobacteria	K	Arac family	tetD	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
AKELHBIC_01891	326426.Bbr_0818	4.15e-258	708.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CZBU@85004|Bifidobacteriales	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
AKELHBIC_01892	216816.GS08_04185	7.07e-183	510.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4CZIV@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
AKELHBIC_01893	216816.GS08_04180	0.0	975.0	COG0596@1|root,COG0596@2|Bacteria,2GK03@201174|Actinobacteria,4CZ9T@85004|Bifidobacteriales	201174|Actinobacteria	S	alpha/beta hydrolase fold	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
AKELHBIC_01894	216816.GS08_04175	0.0	1507.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4CZ1M@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
AKELHBIC_01895	216816.GS08_04170	4.03e-178	499.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4CYQW@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
AKELHBIC_01896	216816.GS08_04165	0.0	1609.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CZUR@85004|Bifidobacteriales	201174|Actinobacteria	MV	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
AKELHBIC_01897	326426.Bbr_0808	1.31e-185	520.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CZ04@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_01898	326426.Bbr_0807	7.59e-316	860.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4CZCT@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class-V	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
AKELHBIC_01899	216816.GS08_04150	3.75e-209	578.0	COG2240@1|root,COG2240@2|Bacteria,2HS59@201174|Actinobacteria,4CYQC@85004|Bifidobacteriales	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	pdxY	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
AKELHBIC_01900	216816.GS08_04145	2.98e-120	343.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4D191@85004|Bifidobacteriales	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
AKELHBIC_01901	216816.GS08_04140	0.0	1001.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,4CYUB@85004|Bifidobacteriales	201174|Actinobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
AKELHBIC_01902	216816.GS08_04135	0.0	1066.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4CYVW@85004|Bifidobacteriales	201174|Actinobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
AKELHBIC_01903	216816.GS08_04130	0.0	1166.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CYT5@85004|Bifidobacteriales	201174|Actinobacteria	C	Succinate dehydrogenase flavoprotein subunit	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
AKELHBIC_01904	216816.GS08_04125	2.06e-233	642.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4CZWJ@85004|Bifidobacteriales	201174|Actinobacteria	C	4Fe-4S dicluster domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
AKELHBIC_01905	216816.GS08_04120	6.02e-142	402.0	COG4122@1|root,COG4122@2|Bacteria,2HXV7@201174|Actinobacteria,4CZZN@85004|Bifidobacteriales	201174|Actinobacteria	S	O-methyltransferase	safC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
AKELHBIC_01906	216816.GS08_04115	8.86e-199	553.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4CZ8R@85004|Bifidobacteriales	201174|Actinobacteria	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
AKELHBIC_01907	216816.GS08_04110	5.39e-307	841.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4CZES@85004|Bifidobacteriales	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
AKELHBIC_01910	216816.GS08_04095	1.27e-308	843.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CYT6@85004|Bifidobacteriales	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
AKELHBIC_01911	216816.GS08_04090	1.81e-158	445.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CZVF@85004|Bifidobacteriales	201174|Actinobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
AKELHBIC_01912	216816.GS08_04085	4.2e-151	424.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,4CYUU@85004|Bifidobacteriales	201174|Actinobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP1	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
AKELHBIC_01913	216816.GS08_04080	2.82e-78	233.0	2A3Y6@1|root,30SGI@2|Bacteria,2IM76@201174|Actinobacteria,4D10Z@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01914	216816.GS08_04075	2.03e-297	818.0	COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria,4CZPX@85004|Bifidobacteriales	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
AKELHBIC_01915	216816.GS08_04070	2.45e-304	833.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CZ6P@85004|Bifidobacteriales	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
AKELHBIC_01916	216816.GS08_04065	8.06e-315	857.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CYUV@85004|Bifidobacteriales	201174|Actinobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
AKELHBIC_01917	216816.GS08_04060	4.52e-153	429.0	2B58P@1|root,31Y2Q@2|Bacteria,2HZMM@201174|Actinobacteria,4D0Y9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3000
AKELHBIC_01918	216816.GS08_04055	8.26e-219	602.0	COG1180@1|root,COG1180@2|Bacteria,2GN2B@201174|Actinobacteria,4CZ5Y@85004|Bifidobacteriales	201174|Actinobacteria	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
AKELHBIC_01919	216816.GS08_04050	0.0	1599.0	COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales	201174|Actinobacteria	C	Pyruvate formate lyase-like	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
AKELHBIC_01920	216816.GS08_04045	3.36e-46	148.0	2EHMB@1|root,33BD3@2|Bacteria,2HZRX@201174|Actinobacteria,4D1G1@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01921	216816.GS08_04040	0.0	1106.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CZ14@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
AKELHBIC_01922	216816.GS08_04035	9.89e-286	779.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4CZC6@85004|Bifidobacteriales	201174|Actinobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
AKELHBIC_01923	216816.GS08_04030	5.54e-146	413.0	COG2011@1|root,COG2011@2|Bacteria,2GY65@201174|Actinobacteria,4CZWG@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
AKELHBIC_01924	216816.GS08_04025	1.2e-280	768.0	COG1135@1|root,COG1135@2|Bacteria,2GJ9P@201174|Actinobacteria,4CZYI@85004|Bifidobacteriales	201174|Actinobacteria	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
AKELHBIC_01925	216816.GS08_04020	2.11e-224	619.0	COG1464@1|root,COG1464@2|Bacteria,2GMNI@201174|Actinobacteria,4CZNB@85004|Bifidobacteriales	201174|Actinobacteria	P	NLPA lipoprotein	-	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
AKELHBIC_01926	216816.GS08_03995	0.0	1683.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales	201174|Actinobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
AKELHBIC_01927	216816.GS08_03990	0.0	1036.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4CZC3@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
AKELHBIC_01928	1121334.KB911072_gene2546	6.76e-20	89.7	COG3206@1|root,COG3206@2|Bacteria,1UNHF@1239|Firmicutes,25H28@186801|Clostridia	186801|Clostridia	M	Plasmid recombination enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
AKELHBIC_01929	1007096.BAGW01000016_gene1000	1.56e-25	104.0	COG3206@1|root,COG3206@2|Bacteria,1UNHF@1239|Firmicutes,25H28@186801|Clostridia,2N8AF@216572|Oscillospiraceae	186801|Clostridia	M	Plasmid recombination enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
AKELHBIC_01930	1519439.JPJG01000056_gene2254	5.09e-37	127.0	2AZMT@1|root,303EX@2|Bacteria,1TUBU@1239|Firmicutes,257XK@186801|Clostridia,2N8SV@216572|Oscillospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01931	658659.HMPREF0983_02930	8.95e-38	129.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
AKELHBIC_01932	478749.BRYFOR_06465	1.41e-207	578.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia	186801|Clostridia	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
AKELHBIC_01934	1235792.C808_01386	2.16e-50	163.0	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia,27PJ6@186928|unclassified Lachnospiraceae	186801|Clostridia	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
AKELHBIC_01935	1291050.JAGE01000001_gene1123	4.98e-195	547.0	COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes,24958@186801|Clostridia,3WIBW@541000|Ruminococcaceae	186801|Clostridia	P	TIGRFAM arsenical-resistance protein	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
AKELHBIC_01936	411474.COPEUT_00384	5.48e-75	226.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
AKELHBIC_01937	1437608.BBIA_0506	2.9e-146	421.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	tnpA	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_01939	216816.GS08_03980	0.0	1186.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4D0BY@85004|Bifidobacteriales	201174|Actinobacteria	I	Psort location CytoplasmicMembrane, score 9.99	yrhL	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
AKELHBIC_01940	216816.GS08_03975	1.59e-244	671.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CYRD@85004|Bifidobacteriales	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
AKELHBIC_01942	216816.GS08_03965	0.0	885.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4CZ4C@85004|Bifidobacteriales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
AKELHBIC_01943	216816.GS08_03960	5.2e-82	243.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4D11U@85004|Bifidobacteriales	201174|Actinobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
AKELHBIC_01944	216816.GS08_03955	7.97e-157	441.0	COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4CYXK@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	gpmB	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	3.1.3.85,5.4.2.11	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
AKELHBIC_01947	216816.GS08_03940	0.0	1080.0	COG0280@1|root,COG0280@2|Bacteria,2GJ5U@201174|Actinobacteria,4CZE6@85004|Bifidobacteriales	201174|Actinobacteria	C	phosphate acetyltransferase	pta	GO:0005575,GO:0005576	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
AKELHBIC_01948	216816.GS08_03935	1.22e-290	794.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4CZ7V@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0409	Acetate_kinase
AKELHBIC_01949	216816.GS08_03930	2.81e-314	857.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4CZBG@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
AKELHBIC_01950	216816.GS08_03925	3.34e-251	692.0	2DSXT@1|root,32UTZ@2|Bacteria,2GKR7@201174|Actinobacteria,4CZBW@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
AKELHBIC_01953	216816.GS08_03785	2.13e-19	82.4	COG1476@1|root,COG1476@2|Bacteria,2IGPZ@201174|Actinobacteria,4D0N7@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,TipAS,Zn_ribbon_2
AKELHBIC_01954	216816.GS08_03775	0.0	1459.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4CZGR@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
AKELHBIC_01955	216816.GS08_03770	2.32e-161	451.0	COG0494@1|root,COG0494@2|Bacteria,2IIY0@201174|Actinobacteria,4D0P8@85004|Bifidobacteriales	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
AKELHBIC_01956	216816.GS08_03765	8.02e-228	626.0	COG0327@1|root,COG0327@2|Bacteria,2GKHZ@201174|Actinobacteria,4CYXC@85004|Bifidobacteriales	201174|Actinobacteria	L	NIF3 (NGG1p interacting factor 3)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
AKELHBIC_01957	216816.GS08_03760	0.0	1858.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CYVK@85004|Bifidobacteriales	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
AKELHBIC_01958	216816.GS08_03755	3.54e-163	459.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4CYS7@85004|Bifidobacteriales	201174|Actinobacteria	T	Response regulator receiver domain protein	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
AKELHBIC_01959	1437608.BBIA_2543	1.48e-184	529.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZA9@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
AKELHBIC_01963	1437608.BBIA_0066	3.07e-14	67.4	2B12Y@1|root,31TGH@2|Bacteria,2GSE7@201174|Actinobacteria,4D1GD@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
AKELHBIC_01964	762211.BSTEL_0336	5.25e-50	160.0	2C1YZ@1|root,343Q3@2|Bacteria,2GUYU@201174|Actinobacteria,4D1PA@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01967	77635.BISU_0820	2.37e-08	54.7	2EBJH@1|root,335JZ@2|Bacteria,2GSCQ@201174|Actinobacteria,4D1KB@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01968	401473.BDP_0983	2.15e-167	488.0	COG0741@1|root,COG0791@1|root,COG3942@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,COG3942@2|Bacteria,2GM11@201174|Actinobacteria,4D2YH@85004|Bifidobacteriales	201174|Actinobacteria	M	Bacteriophage peptidoglycan hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	SLT
AKELHBIC_01971	401473.BDP_0980	3.48e-84	276.0	291ID@1|root,2ZP4W@2|Bacteria,2ISKB@201174|Actinobacteria,4D18I@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01972	401473.BDP_0979	1.67e-174	506.0	29ZCV@1|root,30MBH@2|Bacteria,2HZK2@201174|Actinobacteria,4D0R5@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01979	585530.HMPREF0183_0048	2.8e-83	260.0	COG0338@1|root,COG0338@2|Bacteria,2I9P4@201174|Actinobacteria	201174|Actinobacteria	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
AKELHBIC_01980	880070.Cycma_3994	1.43e-66	226.0	2F0UH@1|root,33TWE@2|Bacteria,4P2NN@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01981	78345.BMERY_0315	1.6e-25	114.0	2DDMI@1|root,2ZIJN@2|Bacteria,2ICIR@201174|Actinobacteria,4D112@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
AKELHBIC_01982	356829.BITS_1625	0.0	1050.0	COG3087@1|root,COG3087@2|Bacteria,2HRQY@201174|Actinobacteria,4CYQ9@85004|Bifidobacteriales	201174|Actinobacteria	D	Cell surface antigen C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Antigen_C
AKELHBIC_01983	1123302.KB904167_gene386	1.31e-10	72.8	COG4932@1|root,COG4932@2|Bacteria,1UXYC@1239|Firmicutes	1239|Firmicutes	M	cell wall anchor domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GramPos_pilinBB,Gram_pos_anchor
AKELHBIC_01984	903814.ELI_1175	9.34e-89	328.0	COG3209@1|root,COG3209@2|Bacteria,1UK8Y@1239|Firmicutes,24M4J@186801|Clostridia,25XIP@186806|Eubacteriaceae	186801|Clostridia	M	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Flg_new,LRR_5
AKELHBIC_01985	33905.BTHE_0501	3.47e-58	199.0	COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales	201174|Actinobacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
AKELHBIC_01986	1437610.BREU_1615	2.34e-74	268.0	COG1196@1|root,COG1196@2|Bacteria,2IR58@201174|Actinobacteria,4D1AN@85004|Bifidobacteriales	201174|Actinobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	CAP
AKELHBIC_01987	1150600.ADIARSV_3510	9.59e-17	76.3	COG3093@1|root,COG3093@2|Bacteria,4NSBZ@976|Bacteroidetes,1ITK1@117747|Sphingobacteriia	976|Bacteroidetes	K	Helix-turn-helix	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
AKELHBIC_01990	1158606.I579_01932	1.55e-23	96.3	2E4E5@1|root,32Z9D@2|Bacteria,1VZM0@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01993	1437610.BREU_3759	3.01e-64	198.0	2BIXD@1|root,32D5N@2|Bacteria,2GTT7@201174|Actinobacteria,4D1KW@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_01994	1437605.BACT_1427	5.58e-39	131.0	COG2161@1|root,COG2161@2|Bacteria,2GPZJ@201174|Actinobacteria,4D19X@85004|Bifidobacteriales	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
AKELHBIC_01995	1437609.BCAL_1168	6.74e-53	166.0	COG4115@1|root,COG4115@2|Bacteria,2IQAJ@201174|Actinobacteria,4D1D5@85004|Bifidobacteriales	201174|Actinobacteria	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
AKELHBIC_02000	401473.BDP_0960	1.42e-234	665.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria,4D0A1@85004|Bifidobacteriales	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02001	401473.BDP_0959	2.4e-269	761.0	COG3505@1|root,COG3505@2|Bacteria,2GNQ7@201174|Actinobacteria,4D08H@85004|Bifidobacteriales	201174|Actinobacteria	U	TraM recognition site of TraD and TraG	-	-	-	-	-	-	-	-	-	-	-	-	TraG-D_C
AKELHBIC_02008	158787.BSCA_1052	3.15e-42	142.0	2B1KQ@1|root,31U26@2|Bacteria,2GTCU@201174|Actinobacteria,4D1M4@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02009	1437608.BBIA_2539	1.99e-195	555.0	COG3550@1|root,COG3550@2|Bacteria,2IEM1@201174|Actinobacteria,4CZPH@85004|Bifidobacteriales	201174|Actinobacteria	S	HipA-like C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HipA_C
AKELHBIC_02011	401473.BDP_0942	0.0	1142.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4D0HT@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
AKELHBIC_02021	1206732.BAGD01000280_gene6510	1.91e-11	67.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4FU72@85025|Nocardiaceae	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
AKELHBIC_02023	1235835.C814_02358	2.71e-15	74.3	COG4734@1|root,COG4734@2|Bacteria,1VCQ0@1239|Firmicutes,24PDW@186801|Clostridia,3WKSS@541000|Ruminococcaceae	186801|Clostridia	L	Domain of unknown function (DUF3846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3846
AKELHBIC_02028	1437608.BBIA_2090	1.95e-84	256.0	2B5AS@1|root,31Y4Y@2|Bacteria,2HZPI@201174|Actinobacteria,4D160@85004|Bifidobacteriales	201174|Actinobacteria	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
AKELHBIC_02029	1437608.BBIA_2091	1.36e-95	295.0	2BMPR@1|root,32G92@2|Bacteria,2H55R@201174|Actinobacteria,4D28G@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02030	1437608.BBIA_2534	1.02e-61	193.0	COG2944@1|root,COG2944@2|Bacteria,2GYQ6@201174|Actinobacteria,4D1PY@85004|Bifidobacteriales	201174|Actinobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02032	1437610.BREU_1787	4.64e-35	121.0	2B12Y@1|root,30DWC@2|Bacteria,2GWJ2@201174|Actinobacteria,4D1TU@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
AKELHBIC_02033	1437610.BREU_1786	7.28e-76	230.0	COG0454@1|root,COG0454@2|Bacteria,2IC6K@201174|Actinobacteria,4D0SR@85004|Bifidobacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
AKELHBIC_02035	762211.BSTEL_0236	1.83e-195	564.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4D01D@85004|Bifidobacteriales	201174|Actinobacteria	F	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
AKELHBIC_02037	1123300.AUIN01000009_gene68	1.05e-68	220.0	COG2852@1|root,COG2852@2|Bacteria,1V2TW@1239|Firmicutes,4HHGA@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02039	158787.BSCA_1054	1.63e-97	286.0	COG5340@1|root,COG5340@2|Bacteria,2IMTJ@201174|Actinobacteria,4D150@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02040	158787.BSCA_1053	5.96e-126	370.0	COG2253@1|root,COG2253@2|Bacteria,2IHDQ@201174|Actinobacteria,4D0UC@85004|Bifidobacteriales	201174|Actinobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
AKELHBIC_02045	158787.BSCA_0402	1.03e-22	95.9	2DNNA@1|root,32Y8E@2|Bacteria,2ISEY@201174|Actinobacteria,4D1A0@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02046	1437608.BBIA_0611	2.71e-52	171.0	2ENST@1|root,33GDY@2|Bacteria,2GS3W@201174|Actinobacteria,4D1ME@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02049	1435051.BMOU_0850	1.16e-43	155.0	2B5N5@1|root,31YHE@2|Bacteria,2GZBA@201174|Actinobacteria,4D2BD@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
AKELHBIC_02050	1437608.BBIA_1654	6.32e-81	259.0	29W79@1|root,31UKN@2|Bacteria,2GU4T@201174|Actinobacteria,4D1IW@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36
AKELHBIC_02055	326426.Bbr_1115	8.64e-179	498.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales	201174|Actinobacteria	L	IstB-like ATP binding protein	istB	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
AKELHBIC_02056	326426.Bbr_1114	0.0	956.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_02058	401473.BDP_0911	1.43e-69	231.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	ydhQ	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AIDA,Pertactin,Pkinase
AKELHBIC_02063	216816.GS08_03745	5.34e-37	129.0	COG0494@1|root,COG0494@2|Bacteria,2HEH8@201174|Actinobacteria,4CZD0@85004|Bifidobacteriales	201174|Actinobacteria	L	NUDIX domain	aspA	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
AKELHBIC_02064	1680.BADO_1070	2.7e-143	406.0	COG2801@1|root,COG2801@2|Bacteria,2H928@201174|Actinobacteria,4CZCP@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
AKELHBIC_02065	78346.BRUM_0813	3.4e-97	286.0	COG2963@1|root,COG2963@2|Bacteria,2IF4K@201174|Actinobacteria,4D0JP@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28
AKELHBIC_02066	216816.GS08_03740	0.0	947.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CZA8@85004|Bifidobacteriales	201174|Actinobacteria	G	Pyruvate kinase	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
AKELHBIC_02067	216816.GS08_03735	6.59e-229	631.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4CYW2@85004|Bifidobacteriales	201174|Actinobacteria	P	Integral membrane protein, TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
AKELHBIC_02068	216816.GS08_03730	0.0	1357.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4CZR0@85004|Bifidobacteriales	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
AKELHBIC_02069	78344.BIGA_1187	3.36e-80	261.0	COG4585@1|root,COG4585@2|Bacteria,2I370@201174|Actinobacteria,4D0JE@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02070	78344.BIGA_1188	1.85e-81	249.0	COG2197@1|root,COG2197@2|Bacteria,2IAQ5@201174|Actinobacteria,4D0E3@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
AKELHBIC_02072	78344.BIGA_1189	4.91e-177	525.0	COG4652@1|root,COG4652@2|Bacteria	2|Bacteria	-	-	XK27_10205	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DUF1430
AKELHBIC_02073	78344.BIGA_1190	5.03e-94	280.0	COG1136@1|root,COG1136@2|Bacteria,2IAY5@201174|Actinobacteria,4D0ZP@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_02074	1680.BADO_0719	8e-95	282.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4D0PG@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
AKELHBIC_02075	216816.GS08_03720	0.0	897.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CZ6S@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
AKELHBIC_02076	216816.GS08_03715	9.81e-201	556.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4CZ53@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0040007,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
AKELHBIC_02077	216816.GS08_03710	8.87e-253	697.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4CZ99@85004|Bifidobacteriales	201174|Actinobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
AKELHBIC_02078	216816.GS08_03705	5.11e-210	580.0	COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria,4CZEV@85004|Bifidobacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02074	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
AKELHBIC_02079	216816.GS08_03700	6.66e-176	493.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4CYTG@85004|Bifidobacteriales	201174|Actinobacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
AKELHBIC_02080	216816.GS08_03695	4.87e-118	338.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4D0X6@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
AKELHBIC_02081	216816.GS08_03690	5.29e-131	372.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CZXD@85004|Bifidobacteriales	201174|Actinobacteria	K	CarD-like/TRCF domain	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
AKELHBIC_02082	216816.GS08_03685	0.0	1545.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CZMD@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
AKELHBIC_02083	216816.GS08_03680	2.47e-164	460.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CZS5@85004|Bifidobacteriales	201174|Actinobacteria	T	Response regulator receiver domain protein	cseB	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
AKELHBIC_02084	216816.GS08_03675	1.4e-240	663.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4CZNA@85004|Bifidobacteriales	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
AKELHBIC_02085	216816.GS08_03670	1.69e-80	239.0	COG1974@1|root,COG1974@2|Bacteria,2GPJI@201174|Actinobacteria,4D0WP@85004|Bifidobacteriales	201174|Actinobacteria	KT	Peptidase S24-like	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
AKELHBIC_02086	326426.Bbr_0743	1.31e-71	225.0	COG1040@1|root,COG1040@2|Bacteria,2I9PA@201174|Actinobacteria,4D11A@85004|Bifidobacteriales	201174|Actinobacteria	S	Phosphoribosyl transferase domain	pyrE_1	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
AKELHBIC_02087	216816.GS08_03665	1.45e-190	529.0	COG0561@1|root,COG0561@2|Bacteria,2HZD0@201174|Actinobacteria,4CZ4N@85004|Bifidobacteriales	201174|Actinobacteria	T	Eukaryotic phosphomannomutase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,PMM
AKELHBIC_02088	216816.GS08_03660	2.03e-84	248.0	COG3824@1|root,COG3824@2|Bacteria,2IS6W@201174|Actinobacteria,4D0YK@85004|Bifidobacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
AKELHBIC_02089	216816.GS08_03655	0.0	920.0	2DNQG@1|root,32YJZ@2|Bacteria,2I2FY@201174|Actinobacteria,4CZE9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02090	216816.GS08_03650	0.0	1918.0	COG1216@1|root,COG5617@1|root,COG1216@2|Bacteria,COG5617@2|Bacteria,2I2FX@201174|Actinobacteria,4CYVM@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
AKELHBIC_02091	216816.GS08_03645	7.16e-75	223.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4D12I@85004|Bifidobacteriales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
AKELHBIC_02092	216816.GS08_03635	1.79e-207	582.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4CYQY@85004|Bifidobacteriales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
AKELHBIC_02093	216816.GS08_03630	0.0	1015.0	COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria,4CYU3@85004|Bifidobacteriales	201174|Actinobacteria	D	FtsK/SpoIIIE family	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE,Yop-YscD_cpl
AKELHBIC_02094	1437610.BREU_1071	3.32e-61	187.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,4D11W@85004|Bifidobacteriales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
AKELHBIC_02095	216816.GS08_03620	0.0	957.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4CYV1@85004|Bifidobacteriales	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2,PAS_4
AKELHBIC_02096	216816.GS08_03600	1.36e-175	495.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4CZGT@85004|Bifidobacteriales	201174|Actinobacteria	S	Haemolysin-III related	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
AKELHBIC_02097	216816.GS08_03595	7.1e-106	306.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4D0QM@85004|Bifidobacteriales	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
AKELHBIC_02098	216816.GS08_03590	5.53e-96	279.0	COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,4D0V6@85004|Bifidobacteriales	201174|Actinobacteria	G	Peptidyl-prolyl cis-trans	fkbP	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
AKELHBIC_02099	216816.GS08_03585	0.0	962.0	COG1760@1|root,COG1760@2|Bacteria,2GJPA@201174|Actinobacteria,4CZ6I@85004|Bifidobacteriales	201174|Actinobacteria	E	Serine dehydratase alpha chain	sdaA	GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
AKELHBIC_02100	216816.GS08_03580	9.54e-121	346.0	2ASIR@1|root,31HZA@2|Bacteria,2IHD9@201174|Actinobacteria,4D0QP@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02102	216816.GS08_03570	6.84e-229	631.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4CZCS@85004|Bifidobacteriales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
AKELHBIC_02103	216816.GS08_03565	3.94e-133	377.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,4CZQX@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
AKELHBIC_02104	216816.GS08_03560	2.63e-101	298.0	COG2919@1|root,COG2919@2|Bacteria,2IR5G@201174|Actinobacteria,4D0SS@85004|Bifidobacteriales	201174|Actinobacteria	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
AKELHBIC_02105	216816.GS08_03555	3.54e-313	853.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CYT3@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
AKELHBIC_02106	216816.GS08_03550	1.14e-230	634.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4CZ9P@85004|Bifidobacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
AKELHBIC_02107	216816.GS08_03545	0.0	2316.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CZ8X@85004|Bifidobacteriales	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
AKELHBIC_02108	216816.GS08_03540	4.23e-147	413.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CZBE@85004|Bifidobacteriales	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
AKELHBIC_02109	216816.GS08_03535	1.49e-93	273.0	COG5573@1|root,COG5573@2|Bacteria,2INXT@201174|Actinobacteria,4D138@85004|Bifidobacteriales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
AKELHBIC_02110	216816.GS08_03530	1.36e-62	192.0	2AYTE@1|root,31QYR@2|Bacteria,2ISWI@201174|Actinobacteria,4D19M@85004|Bifidobacteriales	201174|Actinobacteria	S	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
AKELHBIC_02111	216816.GS08_03520	9.24e-114	326.0	COG1247@1|root,COG1247@2|Bacteria,2HZCB@201174|Actinobacteria,4CZQI@85004|Bifidobacteriales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
AKELHBIC_02112	216816.GS08_03515	0.0	1956.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4CYW1@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
AKELHBIC_02113	216816.GS08_03510	4.54e-266	731.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4CZ6R@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
AKELHBIC_02114	216816.GS08_03505	3.25e-175	489.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CZ82@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
AKELHBIC_02115	216816.GS08_03500	1.86e-129	368.0	2A13J@1|root,30P9F@2|Bacteria,2GKGD@201174|Actinobacteria,4D0QR@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02116	216816.GS08_03495	7.75e-296	809.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4CZ2H@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2427c	Aldedh
AKELHBIC_02117	216816.GS08_03485	0.0	863.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4CZBV@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009069,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019752,GO:0019842,GO:0020012,GO:0030170,GO:0030312,GO:0030682,GO:0036094,GO:0042133,GO:0042783,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0071944,GO:0075136,GO:0097159,GO:1901363,GO:1901564,GO:1901605	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
AKELHBIC_02118	216816.GS08_03480	0.0	970.0	COG0498@1|root,COG0498@2|Bacteria,2GIRY@201174|Actinobacteria,4CYS0@85004|Bifidobacteriales	201174|Actinobacteria	E	Threonine synthase N terminus	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
AKELHBIC_02119	762211.BSTEL_0364	1.12e-297	828.0	COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria,4CYSX@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_24,HTH_5,HTH_IclR,TrmB
AKELHBIC_02120	216816.GS08_03455	7.45e-54	169.0	COG0474@1|root,COG0474@2|Bacteria	2|Bacteria	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	pacL2	-	3.6.3.8	ko:K01537,ko:K12955	-	-	-	-	ko00000,ko01000	3.A.3.2,3.A.3.24	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
AKELHBIC_02121	216816.GS08_03450	2.08e-93	277.0	2B3RX@1|root,31PYJ@2|Bacteria,2IRDS@201174|Actinobacteria,4D16Y@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
AKELHBIC_02122	216816.GS08_03445	8.58e-159	446.0	2ARYF@1|root,31HAF@2|Bacteria,2IK3T@201174|Actinobacteria,4D0YH@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
AKELHBIC_02123	216816.GS08_03440	6.07e-223	614.0	COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria,4CZBH@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_02124	216816.GS08_03435	3.46e-78	233.0	COG1725@1|root,COG1725@2|Bacteria,2IQEW@201174|Actinobacteria,4D152@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
AKELHBIC_02125	1437609.BCAL_2143	1.19e-41	148.0	COG2197@1|root,COG2197@2|Bacteria,2IQKB@201174|Actinobacteria,4D0VR@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
AKELHBIC_02127	471856.Jden_0092	1.27e-75	248.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
AKELHBIC_02128	471856.Jden_0093	6.23e-84	257.0	COG0603@1|root,COG0603@2|Bacteria,2I8NZ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
AKELHBIC_02129	216816.GS08_03430	1.55e-141	400.0	COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria,4CZ8D@85004|Bifidobacteriales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
AKELHBIC_02130	216816.GS08_03425	0.0	1048.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CYYF@85004|Bifidobacteriales	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
AKELHBIC_02131	216816.GS08_03420	1.14e-235	649.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CYZ0@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
AKELHBIC_02132	216816.GS08_03405	3.72e-124	357.0	2B0CX@1|root,31SQ3@2|Bacteria,2GR13@201174|Actinobacteria,4D1JN@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02133	216816.GS08_03400	1.18e-175	490.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4CZSS@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal RNA large subunit methyltransferase J	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
AKELHBIC_02135	216816.GS08_03390	3e-250	686.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4CZ1Z@85004|Bifidobacteriales	201174|Actinobacteria	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
AKELHBIC_02136	216816.GS08_03385	1.7e-210	607.0	COG0457@1|root,COG0457@2|Bacteria,2GKX5@201174|Actinobacteria,4CYXN@85004|Bifidobacteriales	201174|Actinobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
AKELHBIC_02137	216816.GS08_03380	0.0	874.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CZKG@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
AKELHBIC_02138	216816.GS08_03375	2.04e-175	489.0	COG4905@1|root,COG4905@2|Bacteria,2IA3M@201174|Actinobacteria,4CZY7@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
AKELHBIC_02139	216816.GS08_03370	7.47e-128	363.0	COG1418@1|root,COG1418@2|Bacteria,2IFXP@201174|Actinobacteria,4D0P2@85004|Bifidobacteriales	201174|Actinobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
AKELHBIC_02140	326426.Bbr_0696	1.76e-73	221.0	COG0607@1|root,COG0607@2|Bacteria,2ISA2@201174|Actinobacteria,4D2SX@85004|Bifidobacteriales	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
AKELHBIC_02141	216816.GS08_03360	9.78e-190	527.0	COG0476@1|root,COG0476@2|Bacteria,2GJB6@201174|Actinobacteria,4D06G@85004|Bifidobacteriales	201174|Actinobacteria	H	ThiF family	thiF	-	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
AKELHBIC_02142	326426.Bbr_0694	2.93e-201	558.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4CZ4A@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
AKELHBIC_02143	216816.GS08_03350	5.04e-39	129.0	COG2104@1|root,COG2104@2|Bacteria,2GSKM@201174|Actinobacteria,4D1GS@85004|Bifidobacteriales	201174|Actinobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
AKELHBIC_02144	216816.GS08_03345	0.0	962.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CZ50@85004|Bifidobacteriales	201174|Actinobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
AKELHBIC_02145	216816.GS08_03340	1.99e-302	824.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CZ2R@85004|Bifidobacteriales	201174|Actinobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1658	Arginosuc_synth
AKELHBIC_02146	216816.GS08_03335	4.34e-110	317.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4D0VM@85004|Bifidobacteriales	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
AKELHBIC_02147	216816.GS08_03330	7.19e-234	643.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4CZGN@85004|Bifidobacteriales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
AKELHBIC_02148	216816.GS08_03325	4.64e-313	852.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4CZGW@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class-III	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
AKELHBIC_02149	216816.GS08_03320	1.9e-214	593.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CYYX@85004|Bifidobacteriales	201174|Actinobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
AKELHBIC_02150	216816.GS08_03315	2.28e-270	741.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4CZQQ@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
AKELHBIC_02151	216816.GS08_03310	2.14e-259	711.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4CZNC@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
AKELHBIC_02152	216816.GS08_03305	7.54e-144	407.0	2AHAX@1|root,317M8@2|Bacteria,2IPJ5@201174|Actinobacteria,4D11M@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02153	216816.GS08_03300	0.0	1748.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4CYUM@85004|Bifidobacteriales	201174|Actinobacteria	J	Phenylalanyl-tRNA synthetase beta	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
AKELHBIC_02154	216816.GS08_03295	5.24e-258	706.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CZ78@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
AKELHBIC_02155	216816.GS08_03290	1.64e-204	566.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4CYZQ@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
AKELHBIC_02156	216816.GS08_03285	1.89e-190	529.0	COG0619@1|root,COG0619@2|Bacteria,2IDC9@201174|Actinobacteria,4CZM8@85004|Bifidobacteriales	201174|Actinobacteria	P	Cobalt transport protein	ykoC	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
AKELHBIC_02157	216816.GS08_03280	0.0	951.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CYZ6@85004|Bifidobacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ykoD	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ
AKELHBIC_02158	216816.GS08_03275	5.33e-141	398.0	COG4721@1|root,COG4721@2|Bacteria,2IDAN@201174|Actinobacteria,4D00D@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC-type cobalt transport system, permease component	ykoE	-	-	ko:K16925	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.30	-	-	ABC_cobalt
AKELHBIC_02159	216816.GS08_03270	0.0	895.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CYZT@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
AKELHBIC_02160	216816.GS08_03265	1.56e-137	390.0	2AN86@1|root,31D67@2|Bacteria,2HWWU@201174|Actinobacteria,4CZZS@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3043)	-	GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	-	-	-	-	-	-	-	-	-	DUF3043
AKELHBIC_02161	216816.GS08_03260	0.0	964.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CZEI@85004|Bifidobacteriales	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
AKELHBIC_02162	216816.GS08_03255	3.64e-176	492.0	2AUFS@1|root,2ZBYU@2|Bacteria,2I87Z@201174|Actinobacteria,4CYT8@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4191)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4191
AKELHBIC_02163	216816.GS08_03250	0.0	968.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,4CZNK@85004|Bifidobacteriales	201174|Actinobacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
AKELHBIC_02164	158787.BSCA_1953	1.13e-28	114.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CZ6B@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
AKELHBIC_02165	216816.GS08_03240	1.42e-231	640.0	COG0679@1|root,COG0679@2|Bacteria,2GMWC@201174|Actinobacteria,4D0CA@85004|Bifidobacteriales	201174|Actinobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
AKELHBIC_02166	216816.GS08_03230	5.34e-27	104.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CZ5H@85004|Bifidobacteriales	201174|Actinobacteria	S	Maltose acetyltransferase	-	-	2.3.1.18,2.3.1.79	ko:K00633,ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
AKELHBIC_02167	216816.GS08_03230	1.88e-51	167.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CZ5H@85004|Bifidobacteriales	201174|Actinobacteria	S	Maltose acetyltransferase	-	-	2.3.1.18,2.3.1.79	ko:K00633,ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
AKELHBIC_02168	158787.BSCA_2016	8.25e-109	315.0	COG1695@1|root,COG1695@2|Bacteria,2I8K2@201174|Actinobacteria,4D0KJ@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
AKELHBIC_02169	216816.GS08_03225	9.84e-150	422.0	COG2231@1|root,COG2231@2|Bacteria,2ICDU@201174|Actinobacteria,4D03Q@85004|Bifidobacteriales	201174|Actinobacteria	L	endonuclease III	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
AKELHBIC_02170	216816.GS08_03220	3.27e-310	847.0	COG0534@1|root,COG0534@2|Bacteria,2GXXK@201174|Actinobacteria,4CZU6@85004|Bifidobacteriales	201174|Actinobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AKELHBIC_02171	216816.GS08_03215	0.0	1603.0	COG0178@1|root,COG0178@2|Bacteria,2GNMW@201174|Actinobacteria,4CZ5X@85004|Bifidobacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate	uvrA3	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
AKELHBIC_02172	216816.GS08_03205	0.0	1111.0	COG2959@1|root,COG2959@2|Bacteria,2I2HI@201174|Actinobacteria,4CYVN@85004|Bifidobacteriales	201174|Actinobacteria	H	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
AKELHBIC_02173	1437608.BBIA_0139	1.39e-119	356.0	COG1373@1|root,COG1373@2|Bacteria,2HCYQ@201174|Actinobacteria,4D2TP@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_02174	216816.GS08_03195	7.11e-172	480.0	COG1304@1|root,COG1304@2|Bacteria,2HHRH@201174|Actinobacteria,4CZI2@85004|Bifidobacteriales	201174|Actinobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02175	216816.GS08_03190	1e-122	353.0	COG1846@1|root,COG1846@2|Bacteria,2GSTZ@201174|Actinobacteria,4D1IE@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
AKELHBIC_02176	1007103.AFHW01000149_gene800	1.38e-05	45.1	COG0789@1|root,COG0789@2|Bacteria,1V7AK@1239|Firmicutes,4HJVT@91061|Bacilli,276BW@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
AKELHBIC_02177	326426.Bbr_0616	0.0	881.0	COG1373@1|root,COG1373@2|Bacteria,2HJ52@201174|Actinobacteria,4D2TQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_02178	326426.Bbr_0615	7.02e-245	673.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4CZJY@85004|Bifidobacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	adh	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
AKELHBIC_02179	326426.Bbr_0614	9.41e-21	85.5	COG0789@1|root,COG0789@2|Bacteria,2HZK3@201174|Actinobacteria,4D0RM@85004|Bifidobacteriales	201174|Actinobacteria	K	MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
AKELHBIC_02180	326426.Bbr_0614	2.43e-23	92.0	COG0789@1|root,COG0789@2|Bacteria,2HZK3@201174|Actinobacteria,4D0RM@85004|Bifidobacteriales	201174|Actinobacteria	K	MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
AKELHBIC_02181	326426.Bbr_0613	1.74e-113	327.0	COG0239@1|root,COG0239@2|Bacteria,2IJGQ@201174|Actinobacteria,4D11I@85004|Bifidobacteriales	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	-	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
AKELHBIC_02182	326426.Bbr_0612	1.37e-78	234.0	COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D14T@85004|Bifidobacteriales	201174|Actinobacteria	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
AKELHBIC_02183	158787.BSCA_2006	1.36e-42	145.0	COG2246@1|root,COG2246@2|Bacteria,2II4Y@201174|Actinobacteria,4D0YG@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
AKELHBIC_02184	326426.Bbr_0610	2.39e-235	649.0	COG2855@1|root,COG2855@2|Bacteria,2GS6E@201174|Actinobacteria,4CZWB@85004|Bifidobacteriales	201174|Actinobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
AKELHBIC_02185	326426.Bbr_0609	1.23e-184	514.0	COG0583@1|root,COG0583@2|Bacteria,2HZCS@201174|Actinobacteria,4CZT1@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
AKELHBIC_02186	326426.Bbr_0608	1.17e-127	365.0	28XY7@1|root,2ZJU4@2|Bacteria,2GN31@201174|Actinobacteria,4CZQG@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4391)	tmp1	-	-	-	-	-	-	-	-	-	-	-	DUF4391
AKELHBIC_02187	216816.GS08_03105	5.83e-293	799.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
AKELHBIC_02188	216816.GS08_03100	0.0	1402.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CYTB@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
AKELHBIC_02189	158787.BSCA_2042	1.1e-103	300.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4CZQJ@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
AKELHBIC_02190	566552.BIFCAT_01828	1.16e-80	239.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4D0PK@85004|Bifidobacteriales	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
AKELHBIC_02192	216816.GS08_03085	3.58e-241	664.0	COG0385@1|root,COG0385@2|Bacteria,2GMAM@201174|Actinobacteria,4CZ1K@85004|Bifidobacteriales	201174|Actinobacteria	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
AKELHBIC_02194	216816.GS08_03075	7.29e-244	670.0	COG2008@1|root,COG2008@2|Bacteria,2GJ0V@201174|Actinobacteria,4CZ7G@85004|Bifidobacteriales	201174|Actinobacteria	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
AKELHBIC_02195	216816.GS08_03070	9.71e-274	749.0	COG0438@1|root,COG0438@2|Bacteria,2HEH6@201174|Actinobacteria,4CZSN@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
AKELHBIC_02196	326426.Bbr_0600	1.2e-238	662.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZCF@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class I and II	-	-	2.6.1.1,2.6.1.2,2.6.1.66,2.6.1.83	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00034,M00527	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396,R07613	RC00006,RC00008,RC00036,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
AKELHBIC_02197	216816.GS08_03065	5.57e-295	809.0	COG0027@1|root,COG0027@2|Bacteria,2GMCS@201174|Actinobacteria,4CZXH@85004|Bifidobacteriales	201174|Actinobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008776,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044444,GO:0044464	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0389	ATP-grasp,Epimerase
AKELHBIC_02198	158787.BSCA_2049	4.25e-82	243.0	COG0346@1|root,COG0346@2|Bacteria,2II51@201174|Actinobacteria,4D0V7@85004|Bifidobacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
AKELHBIC_02199	326426.Bbr_0598	9.74e-176	490.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4CZGQ@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
AKELHBIC_02200	216816.GS08_03050	0.0	2392.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,2GKG6@201174|Actinobacteria,4CZ7C@85004|Bifidobacteriales	201174|Actinobacteria	F	CobB/CobQ-like glutamine amidotransferase domain	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
AKELHBIC_02201	216816.GS08_03045	3.63e-306	835.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4CYYK@85004|Bifidobacteriales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
AKELHBIC_02202	216816.GS08_03040	0.0	888.0	COG1020@1|root,COG1020@2|Bacteria,2H4CN@201174|Actinobacteria,4D0AP@85004|Bifidobacteriales	201174|Actinobacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02203	216816.GS08_03035	4.95e-140	397.0	COG1020@1|root,COG1020@2|Bacteria,2GIS8@201174|Actinobacteria,4D0BP@85004|Bifidobacteriales	201174|Actinobacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02204	326426.Bbr_0588	7.68e-129	366.0	COG3663@1|root,COG3663@2|Bacteria,2IGMS@201174|Actinobacteria,4D0QQ@85004|Bifidobacteriales	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	nnrE	-	-	-	-	-	-	-	-	-	-	-	UDG,YjeF_N
AKELHBIC_02205	1437610.BREU_0673	1.51e-215	602.0	COG3550@1|root,COG3550@2|Bacteria,2IA5Z@201174|Actinobacteria,4D09R@85004|Bifidobacteriales	201174|Actinobacteria	S	HipA N-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
AKELHBIC_02206	77635.BISU_0426	1.93e-41	137.0	COG1396@1|root,COG1396@2|Bacteria,2IQPX@201174|Actinobacteria,4D19Q@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
AKELHBIC_02207	1437610.BREU_0675	7.52e-60	192.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CZ8K@85004|Bifidobacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
AKELHBIC_02208	216816.GS08_02985	2.72e-42	138.0	2DTWH@1|root,33MZC@2|Bacteria,2GUGG@201174|Actinobacteria,4D1FM@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02209	216816.GS08_02980	0.0	947.0	COG0389@1|root,COG0389@2|Bacteria,2GQX7@201174|Actinobacteria,4CZ0D@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA-damage repair protein (DNA polymerase IV) K00961	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
AKELHBIC_02210	1437610.BREU_0654	3.09e-241	675.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4D0FJ@85004|Bifidobacteriales	201174|Actinobacteria	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
AKELHBIC_02211	1437610.BREU_0653	4.55e-303	830.0	COG0402@1|root,COG0402@2|Bacteria,2HXRT@201174|Actinobacteria,4CZYF@85004|Bifidobacteriales	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
AKELHBIC_02212	1435051.BMOU_1746	7.06e-86	255.0	COG3542@1|root,COG3542@2|Bacteria,2IFG5@201174|Actinobacteria,4D0WA@85004|Bifidobacteriales	201174|Actinobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5,DUF952
AKELHBIC_02213	1437610.BREU_0651	4.99e-165	466.0	COG0834@1|root,COG0834@2|Bacteria,2GN3G@201174|Actinobacteria,4CZ9E@85004|Bifidobacteriales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030,ko:K02424,ko:K17073	ko02010,map02010	M00234,M00236,M00589	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.20	-	-	SBP_bac_3
AKELHBIC_02214	1435051.BMOU_1744	4.54e-161	457.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4D010@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
AKELHBIC_02215	158787.BSCA_1190	2.57e-153	434.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CZ92@85004|Bifidobacteriales	201174|Actinobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028,ko:K02029	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
AKELHBIC_02216	326426.Bbr_0584	0.0	980.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CZ89@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
AKELHBIC_02217	326426.Bbr_0583	3.06e-238	656.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4CZ3K@85004|Bifidobacteriales	201174|Actinobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
AKELHBIC_02218	216816.GS08_02945	3.84e-296	809.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4CZ3I@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the GARS family	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
AKELHBIC_02219	216816.GS08_02940	0.0	953.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CZQF@85004|Bifidobacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	aldH	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
AKELHBIC_02220	216816.GS08_02935	0.0	1291.0	COG1368@1|root,COG1368@2|Bacteria,2HVID@201174|Actinobacteria,4CZ6J@85004|Bifidobacteriales	201174|Actinobacteria	M	Psort location CytoplasmicMembrane, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
AKELHBIC_02221	326426.Bbr_0579	4.11e-201	559.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4CZ99@85004|Bifidobacteriales	201174|Actinobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
AKELHBIC_02222	158787.BSCA_2091	7.37e-28	115.0	COG0803@1|root,COG3443@1|root,COG0803@2|Bacteria,COG3443@2|Bacteria,2GM1K@201174|Actinobacteria,4D07D@85004|Bifidobacteriales	201174|Actinobacteria	P	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment	-	-	-	ko:K02077,ko:K09815	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZinT,ZnuA
AKELHBIC_02223	326426.Bbr_0575	4.76e-250	688.0	COG0701@1|root,COG0701@2|Bacteria,2GJQ0@201174|Actinobacteria,4D057@85004|Bifidobacteriales	201174|Actinobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
AKELHBIC_02224	326426.Bbr_0574	1.56e-177	494.0	COG3689@1|root,COG3689@2|Bacteria,2I8JS@201174|Actinobacteria,4CZZQ@85004|Bifidobacteriales	201174|Actinobacteria	S	TIGRFAM TIGR03943 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1980
AKELHBIC_02225	326426.Bbr_0573	1.36e-111	321.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4D15A@85004|Bifidobacteriales	201174|Actinobacteria	P	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
AKELHBIC_02226	326426.Bbr_0572	3.43e-85	250.0	2AUUP@1|root,31KHW@2|Bacteria,2IKU9@201174|Actinobacteria,4D15K@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02227	1437608.BBIA_0566	6.99e-90	270.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4CYT2@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AKELHBIC_02228	158787.BSCA_2103	3.91e-32	127.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,2I2FK@201174|Actinobacteria,4CZJR@85004|Bifidobacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
AKELHBIC_02230	158787.BSCA_2103	3.12e-68	232.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,2I2FK@201174|Actinobacteria,4CZJR@85004|Bifidobacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
AKELHBIC_02231	326426.Bbr_0569	3.14e-94	275.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4D0XG@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
AKELHBIC_02232	216816.GS08_02915	4.04e-285	778.0	COG0026@1|root,COG0026@2|Bacteria,2GJCU@201174|Actinobacteria,4CYWP@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
AKELHBIC_02233	326426.Bbr_0567	2.07e-111	320.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4CYQZ@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3275c	AIRC
AKELHBIC_02234	216816.GS08_02905	1.66e-223	617.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4D00X@85004|Bifidobacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	yogA	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
AKELHBIC_02235	216816.GS08_02900	0.0	1180.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4CZ2M@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
AKELHBIC_02236	216816.GS08_02895	0.0	889.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GIRW@201174|Actinobacteria,4CZMQ@85004|Bifidobacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
AKELHBIC_02237	216816.GS08_02890	1.38e-172	493.0	COG1361@1|root,COG1361@2|Bacteria,2GP6I@201174|Actinobacteria,4D013@85004|Bifidobacteriales	201174|Actinobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02238	216816.GS08_02885	2.38e-168	472.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4D2SJ@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	GO:0008150,GO:0009405,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
AKELHBIC_02240	216816.GS08_02875	5.84e-274	751.0	COG2865@1|root,COG2865@2|Bacteria,2IBZQ@201174|Actinobacteria,4D03J@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_27
AKELHBIC_02241	216816.GS08_02870	1.02e-201	559.0	COG1737@1|root,COG1737@2|Bacteria,2HY2W@201174|Actinobacteria,4D050@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
AKELHBIC_02242	216816.GS08_02865	0.0	1454.0	COG3534@1|root,COG3534@2|Bacteria,2GP9Z@201174|Actinobacteria,4CZ95@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,Big_3_5,CBM_4_9,DUF1349,Laminin_G_3
AKELHBIC_02243	216816.GS08_02860	1.47e-48	156.0	2B4W6@1|root,31XNV@2|Bacteria,2GZB9@201174|Actinobacteria,4D1T7@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02244	216816.GS08_02855	2.75e-38	140.0	COG1055@1|root,COG1055@2|Bacteria,2GP6U@201174|Actinobacteria,4CZ37@85004|Bifidobacteriales	201174|Actinobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
AKELHBIC_02245	216816.GS08_02840	0.0	933.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4CZGJ@85004|Bifidobacteriales	201174|Actinobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000,ko03000	-	-	-	Aminotran_1_2,GntR
AKELHBIC_02246	216816.GS08_02835	4.67e-146	412.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4CYUS@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
AKELHBIC_02247	326426.Bbr_0549	1.9e-198	551.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CZ5P@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
AKELHBIC_02248	216816.GS08_02825	0.0	1372.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4CYZG@85004|Bifidobacteriales	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
AKELHBIC_02249	216816.GS08_02820	3.59e-315	858.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4CYYP@85004|Bifidobacteriales	201174|Actinobacteria	F	Phosphohydrolase-associated domain	dgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
AKELHBIC_02250	216816.GS08_02815	0.0	865.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CZ2Q@85004|Bifidobacteriales	201174|Actinobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
AKELHBIC_02251	216816.GS08_02810	0.0	945.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4CYZA@85004|Bifidobacteriales	201174|Actinobacteria	E	aromatic amino acid transport protein AroP K03293	aap1	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
AKELHBIC_02252	216816.GS08_02805	1.45e-131	372.0	COG1670@1|root,COG1670@2|Bacteria,2HBE2@201174|Actinobacteria,4CZTR@85004|Bifidobacteriales	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	cysE	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02253	216816.GS08_02800	9.65e-120	341.0	COG1854@1|root,COG1854@2|Bacteria,2GJVF@201174|Actinobacteria,4CYZ4@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
AKELHBIC_02254	216816.GS08_02795	0.0	1262.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4CZ0I@85004|Bifidobacteriales	201174|Actinobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
AKELHBIC_02255	216816.GS08_02790	0.0	1036.0	COG1376@1|root,COG1376@2|Bacteria,2GQ7D@201174|Actinobacteria,4CZ5A@85004|Bifidobacteriales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
AKELHBIC_02256	216816.GS08_02785	1.11e-283	775.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CYY2@85004|Bifidobacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
AKELHBIC_02257	216816.GS08_02780	1.14e-64	208.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CYQ4@85004|Bifidobacteriales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
AKELHBIC_02258	1232436.CAPF01000043_gene330	0.000141	47.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria,4CV60@84998|Coriobacteriia	84998|Coriobacteriia	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
AKELHBIC_02259	401473.BDP_2025	1.59e-224	632.0	COG0477@1|root,COG0477@2|Bacteria,2GJV6@201174|Actinobacteria,4CZH3@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08168	-	M00704	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3.16,2.A.1.3.22,2.A.1.3.6	-	-	MFS_1
AKELHBIC_02260	698961.CGSMWGv6119V5_01143	1.18e-184	517.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZ0Y@85004|Bifidobacteriales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	iunH2	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
AKELHBIC_02261	216816.GS08_02775	6.08e-148	421.0	COG4608@1|root,COG4608@2|Bacteria,2GP46@201174|Actinobacteria,4CYXD@85004|Bifidobacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
AKELHBIC_02262	216816.GS08_02770	5.98e-157	446.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4CZ3U@85004|Bifidobacteriales	201174|Actinobacteria	EP	oligopeptide transport protein of the ABC superfamily, ATP-binding component	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
AKELHBIC_02263	216816.GS08_02765	4.21e-181	509.0	COG1173@1|root,COG1173@2|Bacteria,2GNQ5@201174|Actinobacteria,4CZ84@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
AKELHBIC_02264	216816.GS08_02760	2.78e-206	573.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4CYST@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
AKELHBIC_02265	216816.GS08_02755	0.0	1037.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4CYWF@85004|Bifidobacteriales	201174|Actinobacteria	E	ABC transporter, substrate-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
AKELHBIC_02266	216816.GS08_02750	2.9e-310	846.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4D0GJ@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
AKELHBIC_02267	216816.GS08_02745	4.65e-181	504.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4CZQS@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
AKELHBIC_02268	216816.GS08_02740	0.0	910.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CYRE@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_02270	326426.Bbr_0529	0.0	1422.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ38@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location Cytoplasmic, score 8.87	bga1	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
AKELHBIC_02271	216816.GS08_02685	2.54e-149	424.0	COG0564@1|root,COG0564@2|Bacteria,2GJ2Z@201174|Actinobacteria,4CZB2@85004|Bifidobacteriales	201174|Actinobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
AKELHBIC_02272	216816.GS08_02680	0.0	1227.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4CZ1G@85004|Bifidobacteriales	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
AKELHBIC_02273	216816.GS08_02675	2.39e-189	526.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CZSB@85004|Bifidobacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	tcyC	-	3.6.3.21	ko:K02028,ko:K02029	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
AKELHBIC_02274	326426.Bbr_0522	6.99e-219	605.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4CYSN@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	yecS	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
AKELHBIC_02275	216816.GS08_02665	3.96e-205	570.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CZ6H@85004|Bifidobacteriales	201174|Actinobacteria	ET	ABC transporter, substrate-binding protein, family 3	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
AKELHBIC_02276	216816.GS08_02660	1.15e-194	543.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CZ6H@85004|Bifidobacteriales	201174|Actinobacteria	ET	ABC transporter, substrate-binding protein, family 3	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
AKELHBIC_02277	216816.GS08_02655	8.01e-107	308.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4CZG4@85004|Bifidobacteriales	201174|Actinobacteria	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
AKELHBIC_02278	216816.GS08_02650	6.94e-286	786.0	COG3942@1|root,COG3942@2|Bacteria,2GZG8@201174|Actinobacteria,4CYQJ@85004|Bifidobacteriales	201174|Actinobacteria	D	CHAP domain protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	CHAP
AKELHBIC_02279	216816.GS08_02645	3.16e-205	569.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CZSQ@85004|Bifidobacteriales	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
AKELHBIC_02280	216816.GS08_02640	3.56e-235	652.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4CYYQ@85004|Bifidobacteriales	201174|Actinobacteria	D	Cell division ATP-binding protein FtsE	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
AKELHBIC_02281	216816.GS08_02635	3.59e-263	721.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CZJX@85004|Bifidobacteriales	201174|Actinobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
AKELHBIC_02282	216816.GS08_02630	0.0	881.0	COG1373@1|root,COG1373@2|Bacteria,2HJ52@201174|Actinobacteria,4D2TQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
AKELHBIC_02283	216816.GS08_02625	0.0	954.0	COG0847@1|root,COG0847@2|Bacteria,2IC59@201174|Actinobacteria,4CZY1@85004|Bifidobacteriales	201174|Actinobacteria	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02284	216816.GS08_02620	1.84e-159	446.0	COG0242@1|root,COG0242@2|Bacteria,2GNZ9@201174|Actinobacteria,4CZ7M@85004|Bifidobacteriales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
AKELHBIC_02285	216816.GS08_02615	0.0	889.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4CYZX@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
AKELHBIC_02286	216816.GS08_03170	1.42e-131	384.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4D0GQ@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K05814	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
AKELHBIC_02287	216816.GS08_03165	7.79e-124	360.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4D29F@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
AKELHBIC_02288	216816.GS08_03160	2.99e-200	568.0	COG1653@1|root,COG1653@2|Bacteria,2HP0P@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
AKELHBIC_02289	216816.GS08_03155	2.07e-126	368.0	COG0584@1|root,COG0584@2|Bacteria,2INE1@201174|Actinobacteria	201174|Actinobacteria	C	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4996,GDPD
AKELHBIC_02290	216816.GS08_02585	0.0	1712.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4CZH4@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
AKELHBIC_02291	216816.GS08_02580	0.0	1212.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CZEJ@85004|Bifidobacteriales	201174|Actinobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
AKELHBIC_02292	216816.GS08_02575	8.94e-213	588.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4CZ34@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
AKELHBIC_02293	216816.GS08_02570	1.26e-167	469.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CZJ5@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
AKELHBIC_02294	216816.GS08_02565	3.04e-297	813.0	COG2271@1|root,COG2271@2|Bacteria,2I2GK@201174|Actinobacteria,4CZ0T@85004|Bifidobacteriales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_02295	216816.GS08_02560	0.0	2514.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4CZ49@85004|Bifidobacteriales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
AKELHBIC_02296	216816.GS08_02555	0.0	2573.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4CYQU@85004|Bifidobacteriales	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,PDDEXK_1,UvrD-helicase,UvrD_C
AKELHBIC_02297	216816.GS08_02550	0.0	918.0	COG0515@1|root,COG0515@2|Bacteria,2GIW5@201174|Actinobacteria,4CZ9N@85004|Bifidobacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknK	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
AKELHBIC_02298	216816.GS08_02545	0.0	3618.0	COG4733@1|root,COG4733@2|Bacteria,2GMKC@201174|Actinobacteria,4CZFT@85004|Bifidobacteriales	201174|Actinobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
AKELHBIC_02299	216816.GS08_02540	3.66e-232	652.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CZ3M@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
AKELHBIC_02300	216816.GS08_02535	1e-288	789.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4CZWT@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
AKELHBIC_02301	216816.GS08_02530	0.0	1537.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4CZ3X@85004|Bifidobacteriales	201174|Actinobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
AKELHBIC_02302	216816.GS08_02525	7.49e-32	118.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CZNH@85004|Bifidobacteriales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	BofC_C,PP2C,PP2C_2
AKELHBIC_02303	216816.GS08_02520	1.1e-94	282.0	COG5602@1|root,COG5602@2|Bacteria,2GRHT@201174|Actinobacteria,4D0W6@85004|Bifidobacteriales	201174|Actinobacteria	B	Belongs to the OprB family	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02304	216816.GS08_02515	1.46e-115	334.0	COG1716@1|root,COG1716@2|Bacteria,2IIXF@201174|Actinobacteria,4D0UU@85004|Bifidobacteriales	201174|Actinobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
AKELHBIC_02305	216816.GS08_02450	0.0	2547.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CZ1D@85004|Bifidobacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
AKELHBIC_02306	216816.GS08_02445	0.0	2360.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CZ3W@85004|Bifidobacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
AKELHBIC_02307	216816.GS08_02440	9.1e-151	426.0	2E5CN@1|root,3304R@2|Bacteria,2I2GJ@201174|Actinobacteria,4D0SD@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02308	216816.GS08_02435	2.32e-233	641.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CYRB@85004|Bifidobacteriales	201174|Actinobacteria	L	FES	mutY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
AKELHBIC_02309	158787.BSCA_0673	6.53e-148	417.0	COG0219@1|root,COG0219@2|Bacteria,2IHN9@201174|Actinobacteria,4CZ0E@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	spoU	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
AKELHBIC_02310	33905.BTHE_0898	1.56e-51	163.0	COG2026@1|root,COG2026@2|Bacteria,2GSVC@201174|Actinobacteria,4D1NW@85004|Bifidobacteriales	201174|Actinobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
AKELHBIC_02311	33905.BTHE_0899	6.12e-44	143.0	COG4710@1|root,COG4710@2|Bacteria,2GSB2@201174|Actinobacteria,4D1HJ@85004|Bifidobacteriales	201174|Actinobacteria	S	CopG domain protein DNA-binding domain protein	-	-	-	ko:K18918	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
AKELHBIC_02312	1134445.AJJM01000052_gene2080	1.91e-23	101.0	COG2977@1|root,COG2977@2|Bacteria,2IIA2@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the P-Pant transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
AKELHBIC_02313	216816.GS08_07035	3.77e-150	440.0	COG2271@1|root,COG2271@2|Bacteria,2I32P@201174|Actinobacteria,4D2WZ@85004|Bifidobacteriales	201174|Actinobacteria	G	Sugar (and other) transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,MFS_4,Sugar_tr
AKELHBIC_02314	1680.BADO_1346	2.33e-281	769.0	COG1181@1|root,COG1181@2|Bacteria,2I2GF@201174|Actinobacteria,4D0FN@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02315	443218.AS9A_4425	1.78e-71	269.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,2GISR@201174|Actinobacteria,233YJ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
AKELHBIC_02316	1680.BADO_1345	3.98e-277	760.0	COG0477@1|root,COG2814@2|Bacteria,2IFA0@201174|Actinobacteria,4D0EP@85004|Bifidobacteriales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AKELHBIC_02317	78346.BRUM_0033	1.69e-49	169.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4CZTD@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
AKELHBIC_02318	78346.BRUM_0033	3.22e-209	590.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4CZTD@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
AKELHBIC_02319	216816.GS08_02425	0.0	869.0	COG2848@1|root,COG2848@2|Bacteria,2HHMF@201174|Actinobacteria,4CZGB@85004|Bifidobacteriales	201174|Actinobacteria	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
AKELHBIC_02320	326426.Bbr_0493	4.59e-58	179.0	COG3830@1|root,COG3830@2|Bacteria,2IKS1@201174|Actinobacteria,4D11D@85004|Bifidobacteriales	201174|Actinobacteria	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
AKELHBIC_02321	216816.GS08_02415	0.0	1332.0	COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria,4CZ8W@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N
AKELHBIC_02322	216816.GS08_02410	3.52e-253	695.0	COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria,4CYU5@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
AKELHBIC_02323	216816.GS08_02405	1.37e-149	422.0	COG5578@1|root,COG5578@2|Bacteria,2H1AM@201174|Actinobacteria,4CYSQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
AKELHBIC_02324	216816.GS08_02400	2.26e-216	598.0	COG0395@1|root,COG0395@2|Bacteria,2GJPQ@201174|Actinobacteria,4CYTJ@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
AKELHBIC_02325	216816.GS08_02395	1.14e-218	604.0	COG4209@1|root,COG4209@2|Bacteria,2GKSR@201174|Actinobacteria,4CZIC@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
AKELHBIC_02326	1680.BADO_1396	0.0	1081.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
AKELHBIC_02327	216816.GS08_02375	1.24e-298	815.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4CZNV@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6,2.7.7.12	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955,R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
AKELHBIC_02328	216816.GS08_02370	0.0	866.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CYXZ@85004|Bifidobacteriales	201174|Actinobacteria	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
AKELHBIC_02329	326426.Bbr_0490	2.43e-156	441.0	COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria,4CZMT@85004|Bifidobacteriales	201174|Actinobacteria	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
AKELHBIC_02330	216816.GS08_02360	8.47e-287	782.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CYWW@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
AKELHBIC_02331	216816.GS08_02355	0.0	887.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CZ9Z@85004|Bifidobacteriales	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
AKELHBIC_02332	216816.GS08_02350	0.0	1419.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CZAZ@85004|Bifidobacteriales	201174|Actinobacteria	M	Transglycosylase	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
AKELHBIC_02333	216816.GS08_02345	6.09e-169	473.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4CYYW@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
AKELHBIC_02334	216816.GS08_02340	1.74e-252	693.0	COG0095@1|root,COG0095@2|Bacteria,2GJV5@201174|Actinobacteria,4CZYA@85004|Bifidobacteriales	201174|Actinobacteria	H	Biotin/lipoate A/B protein ligase family	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
AKELHBIC_02335	216816.GS08_02335	1.26e-245	674.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4CZ08@85004|Bifidobacteriales	201174|Actinobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
AKELHBIC_02336	216816.GS08_02330	0.0	1712.0	COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,4CZ2X@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase, S9A B C family, catalytic domain protein	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
AKELHBIC_02337	216816.GS08_02325	0.0	871.0	COG4850@1|root,COG4850@2|Bacteria,2GKPS@201174|Actinobacteria,4CZ13@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
AKELHBIC_02338	216816.GS08_02320	1.94e-92	270.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4D0W7@85004|Bifidobacteriales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
AKELHBIC_02339	216816.GS08_02315	9.74e-294	803.0	COG2816@1|root,COG2816@2|Bacteria,2GJZY@201174|Actinobacteria,4CZE5@85004|Bifidobacteriales	201174|Actinobacteria	L	NADH pyrophosphatase zinc ribbon domain	nudC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
AKELHBIC_02340	216816.GS08_02310	9.92e-207	571.0	COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria,4CYXW@85004|Bifidobacteriales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
AKELHBIC_02341	216816.GS08_02305	2.01e-152	428.0	COG1051@1|root,COG1051@2|Bacteria,2GJGZ@201174|Actinobacteria,4CYT1@85004|Bifidobacteriales	201174|Actinobacteria	F	Domain of unknown function (DUF4916)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4916
AKELHBIC_02342	216816.GS08_02300	5.55e-79	235.0	COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria,4D11J@85004|Bifidobacteriales	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	-	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
AKELHBIC_02343	216816.GS08_02295	5.99e-220	608.0	COG3583@1|root,COG3583@2|Bacteria,2I2GH@201174|Actinobacteria,4CYVC@85004|Bifidobacteriales	201174|Actinobacteria	S	G5	-	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,SLT
AKELHBIC_02344	1437609.BCAL_0952	8.23e-26	102.0	COG1396@1|root,COG1396@2|Bacteria,2HZTJ@201174|Actinobacteria,4D1PW@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K15773	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,HTH_31
AKELHBIC_02345	218140.BPSY_0265	2.29e-165	479.0	COG3550@1|root,COG3550@2|Bacteria,2IH51@201174|Actinobacteria,4D001@85004|Bifidobacteriales	201174|Actinobacteria	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
AKELHBIC_02346	216816.GS08_02285	1.05e-244	682.0	2DDMI@1|root,2ZIJN@2|Bacteria,2ICIR@201174|Actinobacteria,4D00F@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR
AKELHBIC_02347	326426.Bbr_0474	2.89e-311	852.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4CZKW@85004|Bifidobacteriales	201174|Actinobacteria	DM	Psort location CytoplasmicMembrane, score	wcoI	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
AKELHBIC_02348	326426.Bbr_0472	0.0	912.0	2C04M@1|root,32Y5W@2|Bacteria,2IBPG@201174|Actinobacteria,4D07E@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02349	547043.BIFPSEUDO_03283	2.98e-29	107.0	COG3274@1|root,COG3274@2|Bacteria,2GITX@201174|Actinobacteria,4D0JX@85004|Bifidobacteriales	201174|Actinobacteria	S	enterobacterial common antigen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
AKELHBIC_02350	1680.BADO_1370	5.66e-235	655.0	COG1106@1|root,COG1106@2|Bacteria,2GMVX@201174|Actinobacteria,4CZWP@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
AKELHBIC_02351	1680.BADO_1369	8.31e-115	333.0	2B5AK@1|root,31Y4R@2|Bacteria,2IPRY@201174|Actinobacteria,4D15E@85004|Bifidobacteriales	201174|Actinobacteria	S	RloB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	RloB
AKELHBIC_02353	78344.BIGA_0353	1.18e-24	99.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4CZ5F@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0334	NTP_transferase
AKELHBIC_02355	944560.HMPREF9058_1962	2.07e-33	116.0	2E7PK@1|root,33256@2|Bacteria,2ISIC@201174|Actinobacteria,4D6CQ@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02356	78346.BRUM_0813	2.27e-64	201.0	COG2963@1|root,COG2963@2|Bacteria,2IF4K@201174|Actinobacteria,4D0JP@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28
AKELHBIC_02357	78345.BMERY_1183	0.0	1192.0	COG0433@1|root,COG0433@2|Bacteria,2INIE@201174|Actinobacteria,4D1JH@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
AKELHBIC_02358	699248.SRA_06071	1.2e-60	205.0	2C171@1|root,2Z7ZR@2|Bacteria,1VCWV@1239|Firmicutes,4HNFG@91061|Bacilli	91061|Bacilli	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
AKELHBIC_02359	1437608.BBIA_1062	8.69e-46	155.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZUB@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	tnp3521a2	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
AKELHBIC_02360	216816.GS08_09870	6.38e-259	709.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria,4D2KU@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
AKELHBIC_02361	216816.GS08_03825	7.58e-203	562.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria,4D2Q1@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
AKELHBIC_02362	465515.Mlut_06470	3.34e-218	614.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,1W7QH@1268|Micrococcaceae	201174|Actinobacteria	L	PFAM Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
AKELHBIC_02363	216816.GS08_03825	1.25e-169	477.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria,4D2Q1@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
AKELHBIC_02364	216816.GS08_02215	1.14e-271	744.0	COG0582@1|root,COG0582@2|Bacteria,2HB7R@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
AKELHBIC_02365	78344.BIGA_0003	0.0	994.0	COG1484@1|root,COG4584@1|root,COG1484@2|Bacteria,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,IstB_IS21,rve
AKELHBIC_02366	445975.COLSTE_02474	5.24e-80	251.0	COG3631@1|root,COG3631@2|Bacteria,2IHRJ@201174|Actinobacteria,4CW51@84998|Coriobacteriia	84998|Coriobacteriia	S	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
AKELHBIC_02367	700015.Corgl_1392	2.73e-160	459.0	COG3049@1|root,COG3049@2|Bacteria,2GK9Z@201174|Actinobacteria,4CUI0@84998|Coriobacteriia	84998|Coriobacteriia	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
AKELHBIC_02368	216816.GS08_00995	8.53e-230	634.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZTH@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
AKELHBIC_02369	700015.Corgl_1393	6.29e-164	466.0	COG3238@1|root,COG3238@2|Bacteria,2IB1U@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
AKELHBIC_02370	908339.HMPREF9265_1427	7.44e-104	308.0	COG5426@1|root,COG5426@2|Bacteria,1TNZD@1239|Firmicutes,4HTH8@91061|Bacilli	91061|Bacilli	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
AKELHBIC_02371	1445613.JALM01000003_gene4997	6.57e-89	276.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4DZYD@85010|Pseudonocardiales	201174|Actinobacteria	K	Periplasmic binding protein-like domain	-	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
AKELHBIC_02372	398513.BBNG_01833	7.83e-12	63.5	COG2801@1|root,COG2801@2|Bacteria,2H9F1@201174|Actinobacteria,4D2FY@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_2
AKELHBIC_02373	762211.BSTEL_0440	7.01e-52	176.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D0ME@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_02374	326426.Bbr_1115	8.64e-179	498.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales	201174|Actinobacteria	L	IstB-like ATP binding protein	istB	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
AKELHBIC_02375	326426.Bbr_1114	0.0	956.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
AKELHBIC_02376	1437608.BBIA_0904	1.12e-150	433.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D0ME@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
AKELHBIC_02377	702459.BBPR_0778	9.86e-184	519.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_02378	326426.Bbr_1533	1.15e-133	385.0	COG1040@1|root,COG1040@2|Bacteria,2HZQY@201174|Actinobacteria,4D1AY@85004|Bifidobacteriales	201174|Actinobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
AKELHBIC_02379	326426.Bbr_1532	2.33e-193	541.0	COG0758@1|root,COG0758@2|Bacteria,2IFTH@201174|Actinobacteria,4D0JN@85004|Bifidobacteriales	201174|Actinobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
AKELHBIC_02380	398513.BBNG_01485	2.73e-100	301.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
AKELHBIC_02381	702459.BBPR_1619	2.37e-111	328.0	COG2826@1|root,COG2826@2|Bacteria,2GSCE@201174|Actinobacteria,4D1V0@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_38
AKELHBIC_02382	566552.BIFCAT_01245	3.03e-204	572.0	COG3274@1|root,COG3274@2|Bacteria,2GITX@201174|Actinobacteria,4D0JX@85004|Bifidobacteriales	201174|Actinobacteria	S	enterobacterial common antigen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
AKELHBIC_02384	326426.Bbr_0467	5.16e-115	329.0	COG1396@1|root,COG1396@2|Bacteria,2H7PX@201174|Actinobacteria,4D2H1@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
AKELHBIC_02386	547043.BIFPSEUDO_03286	2.72e-22	96.3	2D8CX@1|root,32TR0@2|Bacteria,2GPZP@201174|Actinobacteria,4D1AM@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacteriophage abortive infection AbiH	-	-	-	-	-	-	-	-	-	-	-	-	AbiH
AKELHBIC_02388	326426.Bbr_0464	1.8e-91	291.0	COG1413@1|root,COG1413@2|Bacteria,2GPDJ@201174|Actinobacteria	201174|Actinobacteria	C	Domain of unknown function (DUF4365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4365
AKELHBIC_02390	326426.Bbr_0464	1.66e-141	426.0	COG1413@1|root,COG1413@2|Bacteria,2GPDJ@201174|Actinobacteria	201174|Actinobacteria	C	Domain of unknown function (DUF4365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4365
## 2150 queries scanned
## Total time (seconds): 2.4767580032348633
## Rate: 868.07 q/s