GCA_017366965.1 - 8 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaAFNEFDJD_1 (original name was: gnl|Prokka|AFNEFDJD_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	RaS-RiPP	81,846	103,396

gnlProkkaAFNEFDJD_4 (original name was: gnl|Prokka|AFNEFDJD_4)

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	RaS-RiPP	231,620	254,846

gnlProkkaAFNEFDJD_9 (original name was: gnl|Prokka|AFNEFDJD_9)

Region	Type	From	To	Most similar known cluster		Similarity
Region 9.1	RRE-containing	192,650	213,783

gnlProkkaAFNEFDJD_14 (original name was: gnl|Prokka|AFNEFDJD_14)

Region	Type	From	To	Most similar known cluster		Similarity
Region 14.1	NRPS-like	8,269	51,160	asukamycin	Polyketide:Type II polyketide	4%

gnlProkkaAFNEFDJD_17 (original name was: gnl|Prokka|AFNEFDJD_17)

Region	Type	From	To	Most similar known cluster		Similarity
Region 17.1	lanthipeptide-class-i	1	23,752

gnlProkkaAFNEFDJD_21 (original name was: gnl|Prokka|AFNEFDJD_21)

Region	Type	From	To	Most similar known cluster		Similarity
Region 21.1	NRPS-like	1	4,084

gnlProkkaAFNEFDJD_29 (original name was: gnl|Prokka|AFNEFDJD_29)

Region	Type	From	To	Most similar known cluster		Similarity
Region 29.1	RiPP-like	4,842	19,034

gnlProkkaAFNEFDJD_30 (original name was: gnl|Prokka|AFNEFDJD_30)

Region	Type	From	To	Most similar known cluster		Similarity
Region 30.1	RaS-RiPP	256,512	278,936	streptide	RiPP	100%

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	RaS-RiPP	81,846	103,396
Region 4.1	RaS-RiPP	231,620	254,846
Region 9.1	RRE-containing	192,650	213,783
Region 14.1	NRPS-like	8,269	51,160	asukamycin	Polyketide:Type II polyketide	4%
Region 17.1	lanthipeptide-class-i	1	23,752
Region 21.1	NRPS-like	1	4,084
Region 29.1	RiPP-like	4,842	19,034
Region 30.1	RaS-RiPP	256,512	278,936	streptide	RiPP	100%

Compact view

gnlProkkaAFNEFDJD_1 - Region 1 - RaS-RiPP

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Location: 81,846 - 103,396 nt. (total: 21,551 nt) Show pHMM detection rules used

RaS-RiPP: (PF04055 and TIGR01716)

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core biosynthetic genes

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaAFNEFDJD_4 - Region 1 - RaS-RiPP

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Location: 231,620 - 254,846 nt. (total: 23,227 nt) Show pHMM detection rules used

RaS-RiPP: (PF04055 and TIGR01716)

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core biosynthetic genes

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KnownClusterBlast

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

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gnlProkkaAFNEFDJD_9 - Region 1 - RRE-containing

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Location: 192,650 - 213,783 nt. (total: 21,134 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

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core biosynthetic genes

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
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gnlProkkaAFNEFDJD_14 - Region 1 - NRPS-like

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Location: 8,269 - 51,160 nt. (total: 42,892 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

KnownClusterBlast

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

NRPS/PKS substrates

NRPS/PKS substrate predictions

ctg14_30

Search NORINE for peptide: strict or relaxed

AMP-binding (6..388): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVTSCALIYK
Nearest Stachelhaus code(s):: Ala DVTNFALIYK (62% 8Å match)
Stachelhaus code match:: 80% (moderate)

gnlProkkaAFNEFDJD_17 - Region 1 - lanthipeptide-class-i

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Location: 1 - 23,752 nt. (total: 23,752 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03604))

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core biosynthetic genes

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KnownClusterBlast

Lanthipeptides

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.

gnlProkkaAFNEFDJD_21 - Region 1 - NRPS-like

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Location: 1 - 4,084 nt. (total: 4,084 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 4084:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg21_1

AMP-binding (194..561): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: pro (Pro)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVTALAVVYK
Nearest Stachelhaus code(s):: Ala DVFSLAVVYK (65% 8Å match)
Stachelhaus code match:: 80% (moderate)

gnlProkkaAFNEFDJD_29 - Region 1 - RiPP-like

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Location: 4,842 - 19,034 nt. (total: 14,193 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

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core biosynthetic genes

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
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No matches found.

gnlProkkaAFNEFDJD_30 - Region 1 - RaS-RiPP

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Location: 256,512 - 278,936 nt. (total: 22,425 nt) Show pHMM detection rules used

RaS-RiPP: (PF04055 and TIGR01716)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1