LOCUS       gnlProkkaBNKOPIDN_167  15369 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BNKOPIDN_167.
ACCESSION   gnlProkkaBNKOPIDN_167
VERSION     gnlProkkaBNKOPIDN_167
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:31:13
            Original ID  :: gnl|Prokka|BNKOPIDN_167
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 3721
            Orig. end    :: 19090
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15369
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10869]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10869
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..15369
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15369
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             305..859
                     /locus_tag="ctg159_5"
                     /transl_table=11
                     /translation="MKAAVFFPGIGYHCDKPLLYYSRKLAQECGYEETIALSYTYDGGN
                     IRGNEEKMQQAFESLYEQAEKSLSAIDFDKYDEILFVAKSVGTIIASAYAEKHSIRCRQ
                     ILYTPLKYTYNFVHRDAIAFIGTSDPWSIVPEVQALSQKQQVPMYTYKNANHSLETTDT
                     LENLKILQDVMGKTKGFLERK"
     CDS             1014..1637
                     /locus_tag="ctg159_6"
                     /transl_table=11
                     /translation="MNFQDQIQQIFGTTDIHELKQISRDADNYRCLNADMNNSIISEKK
                     KNTGRKNSFTEEQLAHILALQDRGEKITDIARQYHVSRQTIYSQIKRAYNFSDDPDVKM
                     RMNFMNHDDLCTTIDIDFRHEKIKIKNYTDQIIFRAFGVVTDPDWADFEYFLEERCFPR
                     TRDHRKDILREMGLPFYDPLLIIEKTQGRMSDDHQWIMILKKEG"
     CDS             1644..2465
                     /locus_tag="ctg159_7"
                     /transl_table=11
                     /translation="MEIRNFDAYSPLHKSGHTSKGDQLKWKIDDRWYKADYMGYEGLSE
                     VLVSDLLQKSTCPFPFVEYEAAVIEYNGKIFQGCSSLDFLKANQVLIPLEKLYRRYTGE
                     SLAVKLSDFADVSERIQYLVTQVEEITKIDNFGAYLTAMLEIDAFFMNEDRHTNNIAVI
                     YNEKTQKYELSPFFDQGLCMFADINQDYPIDQSLEYCLEKIEAKPFSSDFDIQLDAAEE
                     LYGIQIGFQFTFKDIQIYLQKNSENYPREVIRRVEQLLRGQMRKYGYLMKK"
     CDS             complement(2573..2746)
                     /locus_tag="ctg159_8"
                     /transl_table=11
                     /translation="MLVCDYIVESIDGDYAHLRRTDLPEEELKLVARALLPFEITEGCR
                     LHYEMMQYSIID"
     CDS             2904..3119
                     /locus_tag="ctg159_9"
                     /transl_table=11
                     /translation="MSKVVKLSSVMEREEKLKEIYEGLEEIKDQLTALIDEYEEEETHT
                     GKADELIEALDALEDASETIEDVLEN"
     CDS             3119..4018
                     /locus_tag="ctg159_10"
                     /transl_table=11
                     /translation="MKEKAYFHLPGLFEFYELYRMFLPLFREHREYFYDWCEIGSIYGA
                     PADCIWGGGRAGFGENDPEEVLELMQEYGISARLTFSNSLLRQEHLSDRKCTALCRLFE
                     RNREPQNGVIIYSELLLEYIKEQYPGLYFVSSTTKVLTDFTQLEEEIRRKDFHYVVPDF
                     RLNKAFDKLNTLSQAEKDKVEFLCNECCWFGCRDRKACYETVSRKNLGENCLEHYCKAP
                     ERERGYLFSKAIENPGFIGINDIRDIYLPMGFSNFKIEGRGLGSALILEFLLYYMTRPE
                     YQIHVREKIYLDSMLDLF"
     CDS             4220..4549
                     /locus_tag="ctg159_11"
                     /transl_table=11
                     /translation="MAIEKSLVSGSMTMLILKLLSEKDMYGYEMIDTLRQKSQNVFELK
                     AGTLYPLLHSLEDKGFLTVYEQEAAGKTRKYYSLTGQGRGFLEKKVEEWKEYSAAVTNV
                     LVMEV"
     CDS             4553..6085
                     /locus_tag="ctg159_12"
                     /transl_table=11
                     /translation="MDEYLKTLLEQIRCKKARPYVKQEFQDHIEDQIEANMQAGMDREQ
                     AEREAVRDMGDPVETGISLDSVHRPQVAWKLLGIIVLISIAGVLIHAGIAGKISENAAA
                     GSDRYVFHVVIGLAVMMILYLLDYTVLARFSKIIAVILLFACLVTLLGGYQLNGARYFI
                     VLPGGRGISMQTLMLFYVPIYGAILYKYHGWGYKGLMRAIIWMIAPVILVYAMPALMPA
                     CMMLVSMLVMLTIAIQKNWFTVRKKKAICGIWAGFLAMPVAAFLIRYLSSSLTEYQIAR
                     LQAIFSDGGEEDYFTGMLHSFWQQNKWIGKSESDVMGNLPAFNADYILTYLSSVYGTIA
                     AVLLCCVLAVLIFAVFNTSMRQKNQLGMMMGCGCGIVFLVNFSINILENLGVFPQSVTF
                     LPFLSAGGSCIIVSYGLMGIVLSTYRYKNIYPRHLKIGFKFDKTKARKALYVSKMSMCI
                     LTGGTVAVMCIAIYWDLCKAYMNIPFKIIAIVLILLLVGNMRRIVQYNEMNR"
     CDS             complement(6164..6484)
                     /locus_tag="ctg159_13"
                     /transl_table=11
                     /translation="MFKEAICLAKPNIELSAEKATAMLYTLADKFLDRAELDEIKEVMR
                     MTRLGQMLMDEGMEKGIELKETDSIKKLMKNMNLTIDQAMNALEVPTDKREKYRKTITP
                     DN"
     CDS             complement(6626..7753)
                     /locus_tag="ctg159_14"
                     /transl_table=11
                     /translation="MILHKKKDTLNRLCCIMKVTKQTLQHLRKKVPLTNTIHYSTFIYN
                     QLKKLNLCKSFSNRVIGHLMSILISIFISGYHGKTTDFSQNSSCPRTTIAHFLNSGKWD
                     DTLLENTLKSSVVEIIYSEAQRTGKPVFCIVDDTIASKTKPSSQAMHPIEDAYFHQSHL
                     KRKQDYDHQAVAVMLSCNGIVLNYAFVLYNKSISKIDIVQNIAKELPEPPVMSYFLCDC
                     WYVSEKIINTFVQKGFHTIGALKTNRLLYPSGMKKKLSELAAELSVTEKGFDPVTVKNR
                     KYYVCRWTIGVFFRQCKTRLALDTYQIRSSKGIQRYWLLMSMAHYICVISTGQYQSFQE
                     GYQLIRSTIQQEKYQYLFQCAKSCVDFEAFMKLAG"
     CDS             7835..8614
                     /locus_tag="ctg159_15"
                     /transl_table=11
                     /translation="MDKNNRVIYGIAGDGEIMRVVICDDEKVTCSEIEKMLSFFAFEKC
                     IKLEVDVFFDGDTLTEYLKKEKAPDILFLDIELPGMNGVEVGKYIRDILRNTDMFMIYI
                     SSKKEYALELFQNQPFDFLIKPIKKERLYHVMEKIFSIIGKNECNFEYKNQGNSYRIMY
                     KDILYFQSDGRKINIVMEKKIESFYGKLSEIEQMCPEGLFLRIHKSYLINMCHAKEITY
                     KWIKMINGDVLDISRSNRVAIRRKLMESMANEIRNDS"
     CDS             8592..9875
                     /locus_tag="ctg159_16"
                     /transl_table=11
                     /translation="MKFVMIAELLLILFSNGIRFYAVKRYIDFFAAREKCLWKYNWILY
                     TFACIGTYIVSIIFESPNLNIISNVIALFLLACPYKIKLSKKFLMTFIIYSINLLADII
                     VVQLLAGYVPGQRVGSAYQFITSLAILIPTAFFSEFTKKKTQDSLPLMNVFILGMIPLV
                     SIVCMHSIATLTENNKPVVLTVAFSLILINSFLFYLYYTLTQFYVAKMNEKKLEQIIDV
                     YAHQLDVVQESQEHIKKLRHDMKHHLIELSAMAQQDKNKDMMRYLEHMEKFMLNPAEKV
                     STGNKEIDGVLNYMLRRADELLKIVNLDIQIPKSLYRNNFNICVILGNLVDNAVRESSK
                     SDEKYLSISVRVQKDILIILIENSYSGSIVQKGNIFQTSQIDTSIHGLGLESVKQVVEA
                     CGGDIKIEYTEKRFWVQVLLYLSNIVEN"
     CDS             10001..10147
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg159_17"
                     /sec_met_domain="TIGR04223 (E-value: 3.3e-09, bitscore:
                     27.5, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKDILKLGMKIVKNTAIKLAERDANTTCPYYGYQAELPCAVKKL
                     KKP"
     CDS             10303..10869
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg159_18"
                     /sec_met_domain="AgrB (E-value: 4.9e-38, bitscore: 121.0,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHRKKFSIRLIEKIGHDEEEREIIQYGLHQGFLILLNLLTTVV
                     CGILWKELPFVLLVFWGIFFLRPYAGGYHADTELRCYFLSTAMMNMVVFLKKTIVLSNI
                     MFIIIWIITVIFIWIYAPVENTIHCLDEDARKKYANNTKKILLCNGIVMLVGIWVNQRI
                     VVDAIIWSQVMIAIAMIAGLWKYST"
     CDS             11081..11458
                     /locus_tag="ctg159_19"
                     /transl_table=11
                     /translation="MRKIIKRTLCVLSATMCVLGTAATASADTVSFNVTIPGDPYSYAV
                     RKADTEQRFYVTGTSFNKSGTLRCRSGKAGQGTSSNSAYISSGSRASSASYTSYAAPNY
                     TYEMYATSGTSGLNVRGRFTP"
     CDS             11515..12606
                     /locus_tag="ctg159_20"
                     /transl_table=11
                     /translation="MRKGLRQAMIVLGICMCLGGCEKETEAKTEPEGETVQSEDGDFFP
                     ESYSEETEKVKFECVVNVPEKFEVTNFHAPIIKGVSNIDAETAYKKYVEGKVVTEEYHD
                     EPTIENEKGNDTYILEDGTVIGLSGVFLYNTPESSIYRQVVRMSERSAPKDNFKFASGD
                     DCTEQVKEELRSLGCPVDEYQFDWFSTSGEDYAILEKRALDDGMIDSQRAKQDGWTEAN
                     NSYEIYGWQLYEGLQVLPPWITSAMSRAFESYQKAPISAVYTKQGMLSLALTEAPCIFE
                     HSDETLEFLKFPEIADILEEKYSALLDDAVYTVTYAKLVLRTYFDEGQKLAAEPVWYFE
                     VTDGTSMEVALLNAVTGTEIFLN"
     CDS             12646..13425
                     /locus_tag="ctg159_21"
                     /transl_table=11
                     /translation="MIILQCFINYLRTDFRRLGKSYRWLAGIVGVVAILFFSLESVLFQ
                     KGLENGNVLSTYVYSTNMTGFLIAYSFCAFPFAGVYPEEQEHKYIRYNVIRGSLKSYVL
                     SKTTVIYISSLSIMILGSVLFLFLCRTYVPWTDWSIDSYGIELNGCYGSILEEGHVILY
                     CTLYALNLGLIAGALSNMAALCSVFISNTVLVLVFPVLAFRVLVSVNIADYNIYAFYAY
                     TKIFASDGVNLLFLTVISVGISALSAAGCYWGLKKKM"
     CDS             13441..14319
                     /locus_tag="ctg159_22"
                     /transl_table=11
                     /translation="MKTLKYIMKTSAQKIFNVKFATFCAAFLILSWTYDQPYLQFVKEK
                     NYPISWCIFPFYMSSFGILSIFYVGIVYIHSDVPFMQHINMYQVIRTGRERWALSQIAG
                     ILIRSFFAVILSAIAAVLPFWGHIEFSTDWGKVIKTLASQRADEGFGFGMGQMLDFRFH
                     YGILGKFTPVQLMIITVLICTLICTFLGILMFLISLYAGKILAVAVTMMSVVALFIVEN
                     IYGEWKLIVAHVVPTYWAEVALSATPVSGRYRIPSLTYIFTFLIVAVVFMSVIIFCKVK
                     HTEFHWENEDA"
     CDS             14344..14988
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 162.4; E-value:
                     2.3e-49)"
                     /gene_kind="transport"
                     /locus_tag="ctg159_23"
                     /transl_table=11
                     /translation="MEKQRIEVNHVFKSFKEKEVLKDVSLTCESGKIYGIVGHNGSGKT
                     VLFKCICGFFYCDRGEIRVNGKCMGKDADMLQNAGIIIEEPGFLRQWSGFHNLEFLYTI
                     RNKLNKKYMYSVLEKVGLEPRSKIPVGKYSLGMRQRLAIGQAIMENPDILILDEPMNGL
                     DKNGVQEMRGLFEQMKNEGKLIILASHNREDIDVLCDEVYEMENGILKKRR"
     CDS             15014..15202
                     /locus_tag="ctg159_24"
                     /transl_table=11
                     /translation="MIIPYEIFKENKRFKESIDNAQNETDILLYNAAKEYSNSVRKRAK
                     AVTDIIMERIEKEIKNS"
     CDS             complement(15236..15367)
                     /locus_tag="ctg159_25"
                     /transl_table=11
                     /translation="MTKKELFFTKNTNYFTLPAFTEDDYSALSLTPLMSGKMTRKDI"
ORIGIN
        1 tgccttattc ttcccaagag aatccccact ggtaaatgct ttatacaaag cttacacaga
       61 tgtaacaggc gatacagaga acaagccgat ggtgatcggc ggtggaactt atgcaaaatc
      121 tcttaagaat atcattgcat ttggacctga gaagccggga attgattatc gtatccacag
      181 cgcagatgaa tttattctcg tatccggtat ggaagaggca gttctggttt atatggaagc
      241 aattaagaat cttctggcaa tctgatgaaa aatgatggag cagctattaa atggagagca
      301 gaacatgaag gcagcagtat ttttccctgg tattgggtat cattgtgaca agccactttt
      361 atattattca cgaaagctgg cgcaggaatg tggctatgaa gaaacaattg cattaagcta
      421 tacttatgat ggcggaaata tccggggaaa tgaagaaaaa atgcagcagg cattcgaaag
      481 cctttatgaa caggcagaga aaagtctttc tgccattgac tttgacaaat atgatgaaat
      541 attatttgtc gcaaaaagcg taggcacgat catagcatcc gcatatgcag agaaacacag
      601 catcagatgt cggcagatac tatacacacc attgaaatac acatataatt ttgttcatag
      661 agatgccatt gcctttatcg gaacttcaga tccatggagt attgttcctg aagtacaggc
      721 tctttcacaa aaacagcagg tgccaatgta tacttataaa aatgcaaacc attcactgga
      781 aacaacagat acactggaaa acctgaaaat tctccaggat gttatgggga aaaccaaggg
      841 atttttggag cggaaataag aaaaagcaca taatcatatt gagtagatat gggtgaagaa
      901 gtgtcaagaa actatttctt gacacttctt tttgctccat gctatactca attagacaaa
      961 ctgttatatg tgaaagtggt ttccataatg tctttttagg tggtgatgtg aatatgaact
     1021 ttcaagatca gatacagcag atttttggaa caacagatat tcatgaactg aagcagatat
     1081 ccagagatgc cgacaattac agatgcttga atgctgatat gaataacagc attatttcag
     1141 aaaagaaaaa aaataccgga aggaaaaatt cgtttacaga agaacagctg gcacatattt
     1201 tggcactgca ggaccgggga gaaaaaatta cagatattgc cagacagtat cacgtttccc
     1261 gtcagacgat ttacagtcag ataaagcgag cctataattt ttctgatgat ccggatgtga
     1321 aaatgcgtat gaatttcatg aatcatgatg atctgtgtac aacgatagat attgatttca
     1381 ggcatgaaaa aattaagatt aaaaactata cagatcagat tattttccgg gcatttggag
     1441 ttgtaactga tccggattgg gctgattttg aatattttct ggaagaacgc tgttttccca
     1501 gaacacgcga tcacaggaaa gatattctga gagagatggg gcttccattt tatgatccgt
     1561 tattaattat tgaaaaaaca caggggcgca tgtcagatga tcatcaatgg attatgattc
     1621 taaaaaagga gggctgatca aaaatggaaa ttcgcaattt tgatgcatat tctcccttgc
     1681 ataagagcgg tcatacttcc aagggagatc agctcaaatg gaaaattgat gacaggtggt
     1741 ataaggctga ttatatggga tatgaaggtt tatctgaagt tcttgtatct gaccttttgc
     1801 agaagagtac ctgtcctttc ccttttgttg agtatgaagc agctgtaatt gagtataatg
     1861 ggaaaatatt tcagggctgt tccagtttgg attttctgaa agcaaatcag gttctgattc
     1921 cgctggaaaa attgtatcgt cgatatacag gtgaaagtct ggcagtaaag ctctcagatt
     1981 ttgcggatgt ttcagaacgc attcagtacc tggtaactca ggtggaagaa attactaaaa
     2041 tagataattt tggagcgtat ctgactgcaa tgctggaaat agatgcgttt ttcatgaatg
     2101 aggacagaca taccaacaat attgcggtca tttataatga aaaaacacag aaatatgaac
     2161 tgagtccttt ttttgatcag ggactttgta tgtttgccga cataaatcag gattatccta
     2221 ttgatcagtc attggaatat tgtctggaaa aaattgaggc gaagccattt agctctgatt
     2281 ttgatataca gctggatgca gcagaagaac tgtatggcat tcagattggt ttccaattta
     2341 cctttaaaga tattcagata tacttacaga agaattcgga aaattatccc agggaagtaa
     2401 taagacgcgt ggagcagctg ttaagagggc agatgcgtaa atatgggtat ctgatgaaaa
     2461 aatgatatta cagagagtgt atgaagttac aggcagataa aggataaaaa agtcacttat
     2521 ctgccttttc tggtaaactt tttgtaacgg ctgtgaggcg gagactgtca aatcagtcaa
     2581 tgatactata ctgcatcatt tcataatgta atctgcatcc ttctgtaatc tcaaagggca
     2641 gaagtgcccg tgctacgagt tttaactctt cttcaggcag atctgttctg cgaagatgtg
     2701 catagtcacc gtcaatagat tctacgatat aatcacaaac taacataaaa atcctccact
     2761 ttatattttg cgtaacgcaa tgatcatatc tatagaatac cacagaggaa aagggtatca
     2821 caagtgcctt cagattatat agacataaaa agagggcagt gttataattt ttcctaaaga
     2881 aaatgcatat gggaggtatc gcaatgtcta aagttgtaaa gctttcatcc gtaatggaaa
     2941 gggaagaaaa attaaaggaa atctatgaag gtctggaaga gataaaagat cagctgacag
     3001 cactgattga tgagtatgaa gaagaggaga cacatacagg aaaagcagat gaactgatcg
     3061 aagccctgga tgctcttgag gatgcttcgg aaaccataga ggatgtgctg gaaaattaat
     3121 gaaggagaaa gcatattttc acctgcccgg gctgtttgag ttttatgagc tgtaccggat
     3181 gttcctgcct ttattccggg aacacaggga atatttttac gactggtgtg aaattggctc
     3241 catatatggt gctccggcag actgtatctg gggtggaggc agggctggct tcggagagaa
     3301 tgacccggag gaggttcttg aactgatgca ggaatatggg atttctgccc gactgacttt
     3361 cagcaattcc ctgcttcgcc aggagcacct ttcagacaga aaatgcactg cactgtgccg
     3421 gttgtttgag agaaacagag aaccgcaaaa cggcgtgatc atttattcag aattgctctt
     3481 ggaatatatt aaggagcagt atccgggact ctattttgtt tcctccacta ccaaggttct
     3541 gacagatttt acacagcttg aggaagaaat caggagaaaa gatttccatt atgttgtgcc
     3601 ggatttccgg ctaaacaagg cttttgataa gttaaataca ttgtctcagg ctgagaagga
     3661 caaagtagaa tttctctgca atgaatgctg ctggttcggc tgcagggaca gaaaagcctg
     3721 ctatgaaacg gtcagccgca agaatctggg tgaaaactgc ctggagcatt actgcaaggc
     3781 accggagaga gagaggggct atcttttttc aaaagctata gagaatccag ggtttattgg
     3841 aatcaatgat atccgggata tctatctgcc aatgggattt tcaaatttta aaatagaagg
     3901 aagaggactc ggcagtgccc tgatactgga atttctgctc tattacatga ccagaccgga
     3961 ataccagata catgtcagag aaaaaatata tctggacagt atgctggatc tgttttgaga
     4021 gatttatacc accgcattgt gttactatat gacaatgcgg tggtttttct gtccgaaaaa
     4081 gtatgtagat acctgaactc ggttgccata gcagtgaagt tttcaaaatt attccggaaa
     4141 cagttgacat agcatatagg ttcttatatt atatagataa ccgatatata gacaatctat
     4201 acaatgggag gtgaatacta tggctattga aaaatcactg gtttccggga gtatgacaat
     4261 gcttatactg aaattgctgt cagaaaagga tatgtatgga tatgagatga tcgataccct
     4321 gcgacagaaa tctcagaacg tgtttgaact gaaagcagga actctgtatc cgttactgca
     4381 cagtctggag gataagggat ttctgacagt atacgaacag gaggcagccg gaaagaccag
     4441 aaagtattac agtctgactg gacagggaag gggatttctg gaaaaaaaag tagaagaatg
     4501 gaaagagtat tctgcagcag tgaccaacgt gcttgtaatg gaggtgtgat ctatggacga
     4561 atatctgaaa acattactgg aacagattcg ctgtaagaaa gcgcggcctt atgtaaaaca
     4621 ggaatttcag gatcatatag aagatcagat cgaggcaaat atgcaggcag gtatggatcg
     4681 tgaacaggca gagagggaag ctgtccggga tatgggagat cctgtggaaa caggaatctc
     4741 tcttgacagt gtccacaggc ctcaggttgc atggaaactt ctggggataa tcgttcttat
     4801 cagcattgca ggcgttttga tacatgcagg gattgccgga aaaatcagtg agaacgctgc
     4861 ggccggttcg gacagatatg tgttccatgt tgtgatcgga cttgcagtta tgatgatttt
     4921 atatcttctg gattacactg tactggcaag attttcgaaa ataattgccg tcattttact
     4981 gtttgcctgt ctggttacat tgttgggtgg ctatcagtta aatggggcaa gatacttcat
     5041 tgtactgccg ggaggaagag gaatatccat gcagactctg atgctgtttt atgttcccat
     5101 atatggagca attttgtata aatatcatgg atggggatat aagggcttga tgagagcaat
     5161 catatggatg attgcaccgg ttatattggt ctatgccatg ccggcgctta tgccggcctg
     5221 catgatgctg gtatctatgc tggttatgct gacaatcgca attcaaaaga actggttcac
     5281 tgtgagaaaa aagaaagcca tctgcggaat ctgggctggt tttctggcta tgcctgtggc
     5341 agcttttctg atcaggtatc tgagcagcag tctgacagaa tatcagattg cacgtttaca
     5401 ggctattttt tcagatggtg gagaggaaga ttatttcacc ggaatgctac attcattctg
     5461 gcagcagaat aaatggatag ggaaaagcga atcagatgta atgggaaatc tgccggcttt
     5521 taatgcggat tatattttga cctatctgtc atctgtatat ggaacaattg cagccgtgct
     5581 tttatgctgt gttctggcag ttttgatttt cgcagttttt aacacttcca tgaggcagaa
     5641 gaatcagctt ggaatgatga tgggatgtgg atgcggaatt gtattccttg taaacttttc
     5701 cataaatatc ctggaaaatc tgggtgtatt tccacaatca gtaacatttc ttcccttttt
     5761 atcagcagga ggaagctgca ttatagtttc ctatggactg atggggattg tactgagtac
     5821 atacagatat aaaaatatct atccacggca tctgaaaata ggttttaaat ttgataaaac
     5881 caaagcgaga aaagccctgt atgtctcaaa aatgtccatg tgcatattga caggaggcac
     5941 tgttgctgtt atgtgcattg ccatatattg ggatttgtgc aaggcttata tgaatattcc
     6001 gtttaaaatt atagccattg tactgatatt gcttctggtt ggaaatatga gaaggattgt
     6061 gcagtacaat gaaatgaaca gatagaaaat gtaaaaaaac tgtattaaaa aaaataccgc
     6121 cattattgat tgtgataagt caatatggcg gtacttttat ccattaattg tcaggagtga
     6181 ttgtcttgcg gtatttttca cgtttatctg tcggaacctc cagagcgttc attgcctgat
     6241 caatggtcag gttcatattt ttcataagtt ttttgataga gtcggtttct ttaagttcaa
     6301 tacccttttc catgccctca tccattaaca tctgtccaag tctggtcatt cgcattacct
     6361 ccttaatttc gtctaactca gctctgtcta agaacttgtc agccagtgta tacaacatag
     6421 cggttgcctt ttcagcactc agctcaatat tgggctttgc cagacaaatt gcttctttaa
     6481 acatatcctt gcggctcatt tttccggaca tcaatggtgt cagggaaaga gcagcgtaat
     6541 catcttcagt aaaagcttca ccgttatcct gcttctgctt taattattaa gctataaatg
     6601 agcaaatttg aaaaaatgca caaaactatc ctgctaattt cataaacgct tcaaaatcga
     6661 cacaggattt tgcacattga aacaaatatt gatacttttc ctgctgaatg gtactgcgaa
     6721 tcagttgata tccttcctgg aaagactgat attgcccagt gcttataaca cagatataat
     6781 gtgccattga catcaacagc cagtacctct ggattccttt cgaggaacgt atctgatagg
     6841 tatccaacgc cagacgggtt ttacattgtc tgaaaaatac ccctattgtc caccggcaca
     6901 cataatattt tcggtttttg actgtcacag ggtcaaatcc tttctctgtt accgataatt
     6961 cagcagcaag ttcgctgagc ttctttttca ttcctgacgg gtacagcagg cggtttgttt
     7021 ttaaagctcc aatggtatgg aaccccttct gtacaaatgt gttgattatt ttttcagaaa
     7081 cataccagca gtcacaaagg aaatatgaca tgactggagg ttctggcagt tcctttgcaa
     7141 tgttctgcac aatatcaatc ttggaaatgg atttattgta cagtacaaaa gcatagttca
     7201 ggacaatgcc attgcacgaa agcataacag caactgcctg atggtcataa tcctgttttc
     7261 tctttaaatg ggactggtgg aaatacgcat cttcaattgg atgcatagcc tgtgacgaag
     7321 gctttgtctt tgaagctatg gtatcatcca caatacagaa aacaggtttt ccggtgcgct
     7381 gtgcttctga ataaataatt tcaactacgg aggattttaa agtattttca agtaaggtat
     7441 catcccattt cccagaattg aggaaatgtg cgatggtagt tctggggcag gaactgtttt
     7501 gtgaaaagtc ggtagtcttt ccgtggtaac ctgagataaa gatactgatc aggatactca
     7561 tgagatgacc gatcactctg ttcgaaaaag atttgcataa atttaatttc ttaagctggt
     7621 tgtatatgaa tgtagaataa tgtatagtat ttgtgagagg caccttcttt cgtaaatgtt
     7681 gcaatgtttg tttggtcact ttcattatac aacacaaacg atttaaggtg tctttctttt
     7741 tatgcaaaat cacgaacttg ctcatttata gttatattct tgctaacata cttctaaaga
     7801 tgaagtttat gaaaaattga aaggagtagc ttgcatggat aaaaataata gagtaatata
     7861 cggaatagca ggagatggag aaataatgcg agtagtaata tgcgatgatg agaaagtaac
     7921 ttgttcagag atagagaaaa tgcttagttt ttttgcgttc gaaaaatgta taaagttgga
     7981 agtggacgtg ttttttgatg gagatacttt gacagaatat ttgaaaaaag aaaaagctcc
     8041 agacattctt tttttagata ttgaacttcc gggaatgaat ggggttgagg tcggaaaata
     8101 tatcagggat atattgagga atacagatat gtttatgata tatatatctt ctaaaaagga
     8161 atatgcttta gaactgtttc aaaaccagcc atttgatttt ctgataaaac caataaaaaa
     8221 agaacggctg tatcatgtta tggagaaaat atttagtatt attggaaaaa atgagtgcaa
     8281 ttttgagtat aaaaatcaag gaaatagtta cagaattatg tacaaagata ttttgtattt
     8341 tcaaagtgat ggaagaaaaa ttaatattgt aatggaaaag aaaatagaaa gtttttatgg
     8401 taagttatct gagattgaac agatgtgtcc agaggggttg tttttgcgta ttcacaaatc
     8461 atatttgatc aatatgtgcc atgcgaaaga aattacttat aaatggataa aaatgataaa
     8521 cggagatgtg ttggatatta gcagatcgaa ccgtgtggct ataagaagaa aactaatgga
     8581 gagtatggca aatgaaattc gtaatgatag ctgaactgtt gcttatattg ttttcaaatg
     8641 gaattcgatt ttatgcagtt aaaaggtaca tagatttttt tgctgccaga gaaaaatgtc
     8701 tatggaaata taattggatt ctatatactt ttgcatgtat tgggacttat attgttagta
     8761 ttatatttga atcgccaaat ttgaatataa tttcgaatgt cattgcttta tttctactgg
     8821 catgcccgta taagataaag ctgtctaaaa aattcctaat gacatttatt atatattcta
     8881 ttaatttact agcagatatt atagttgttc aactgttggc aggatatgtt cccggacaaa
     8941 gagtaggctc agcttatcaa tttataacta gcttggcgat tttaattcca actgcttttt
     9001 tttcagaatt tacaaagaaa aaaacgcagg attctctacc acttatgaat gtattcatat
     9061 tgggtatgat tcccttggtt agcattgttt gtatgcacag cattgcaact ttaacagaaa
     9121 ataacaaacc tgtagttctt acagtagcat tcagtttgat actcatcaat tcatttttgt
     9181 tttatttata ttacacatta acccaatttt atgtggcgaa aatgaatgag aagaaactgg
     9241 agcagataat tgatgtatat gcacatcagc ttgatgtggt gcaggaatct caggagcata
     9301 ttaaaaaatt gcgtcacgat atgaagcatc atttaataga attatctgct atggcacagc
     9361 aggataagaa taaggatatg atgagatatt tagaacacat ggaaaaattt atgttaaatc
     9421 cagcagaaaa agtttcgaca gggaataaag aaattgatgg ggttttaaat tacatgctca
     9481 ggcgtgcgga tgaattattg aaaattgtga atctggatat tcagattcca aaatcactat
     9541 acagaaataa ttttaatatt tgtgtgattt taggaaattt ggtagataat gcggtcaggg
     9601 aatcgagtaa atctgatgaa aagtatttat ccattagtgt gcgtgtgcaa aaagatatcc
     9661 tgattatttt gatagaaaat agttatagtg gttcaattgt gcaaaaaggt aatatatttc
     9721 aaaccagcca aattgataca tctattcacg ggttaggttt ggaaagtgtg aaacaggtag
     9781 tagaagcatg tggtggagat ataaagattg aatatacgga aaaacgattt tgggtacagg
     9841 ttttattata tttgtcaaat attgtagaga actaaaaaga gccacttggc tcttttttag
     9901 ttccaatttt gacaaaaaaa tatacagttt ttgacaataa aaggcatatg aagagaattt
     9961 atggtatgtt ataaaaaata tatgtttagg aggatgtaac atgaaaaaag atattttgaa
    10021 attgggtatg aaaatagtaa aaaatactgc tataaagtta gcagagcgtg atgcaaatac
    10081 aacatgtccg tattacggtt atcaggcaga acttccatgt gccgtcaaaa agctgaaaaa
    10141 accgtgattt tgtaaattgg ttgatttttt aaagaaaata tggaagtata tagttccttt
    10201 taggaacaat aaaagtaatc aggttgccat agactataga gttttcttat gaaaacatag
    10261 tagtttgtgg caactgtgtt tttgaagaaa atgaggtttt taatggaaaa gcatagaaaa
    10321 aaattctcaa tacgattgat agaaaaaatt ggacatgatg aggaagaacg agaaattatc
    10381 caatatggat tgcatcaggg gtttctgata ttacttaatt tattgacaac agtagtttgt
    10441 ggaatactct ggaaagaact gccttttgta ttattggtat tttgggggat attttttttg
    10501 agaccttatg ctggaggata tcatgcagat acagaattac gttgttattt tctatcgaca
    10561 gcaatgatga acatggttgt ctttttgaaa aaaacaatag ttttatcaaa tataatgttt
    10621 ataataatat ggattattac tgttatattt atttggatat atgccccagt agaaaatact
    10681 attcattgtt tagacgaaga tgcacgcaaa aagtatgcga ataatacaaa gaaaattttg
    10741 ttatgtaatg gaatcgtaat gctagtggga atatgggtaa accaaagaat tgtcgtagat
    10801 gcaattattt ggagtcaagt gatgattgcg attgcaatga tagctggatt atggaaatat
    10861 agtacctaat aaataattta tataggagaa taaagaaaaa agtgtgaata tacaaaaagg
    10921 cattagtctt gacagaagtt ccatttttga cacaattata tacagttttt ggcaaggtgc
    10981 gttttaagag ataattctat gctatagtaa attcaacaaa caagttggtg ccaatgttgt
    11041 ttaataactg aaaaactttt ttagaaaggg gaaatgattt atgagaaaaa ttattaaaag
    11101 aacactttgc gttttaagtg caacaatgtg tgtgctgggg acagcagcta cagcaagtgc
    11161 ggatacagtt tcatttaatg tgacgattcc gggtgatcca tactcttatg cagtaaggaa
    11221 agcggataca gaacagagat tctatgtaac aggaacatcg tttaataaaa gcggtacatt
    11281 gagatgcaga tctggaaaag caggacaggg aacaagctcc aattcggcgt atatttcttc
    11341 tggttcaaga gcttcctctg ccagctacac atcttatgca gcgcctaatt atacatacga
    11401 gatgtatgct accagtggaa caagtggatt gaatgttagg ggacgtttca caccgtaaat
    11461 aaaactgtag atgaaggcgg agaaatccgc cttcgttttt tcaaggagga ctatatgaga
    11521 aaaggcttga gacaagcaat gatagtgctg ggaatatgta tgtgtttagg gggctgtgaa
    11581 aaagaaacgg aggcaaaaac agagccggaa ggagagacgg tacagagcga agacggagat
    11641 ttttttccgg aatcatattc agaggaaaca gagaaggtga aatttgagtg tgtagtaaac
    11701 gttccggaga aatttgaagt taccaacttc cacgccccta ttataaaagg tgtttctaac
    11761 attgatgcag aaacagctta caaaaaatat gttgagggaa aagtagttac agaagaatat
    11821 catgacgaac caactattga aaatgaaaaa ggaaatgata cgtatatatt ggaggacgga
    11881 acagtgatag ggttatcggg agtgtttctg tacaatacac ccgaatcctc aatatacaga
    11941 caggtagtga gaatgagcga acgcagcgct ccaaaagata attttaaatt tgcatcagga
    12001 gacgattgca cagaacaggt aaaagaagaa ttaagatcac tgggctgccc tgttgatgaa
    12061 tatcagtttg actggttctc taccagcgga gaagattatg caatattgga gaagcgagct
    12121 ttagatgacg gaatgattga cagtcaaagg gcaaaacagg acggctggac agaagccaat
    12181 aattcttatg agatatatgg gtggcagctt tatgagggac tgcaggttct tccgccgtgg
    12241 ataacaagcg cgatgtcacg ggcgtttgaa agctatcaga aagcgcccat atctgctgtt
    12301 tacacaaaac agggtatgtt gagtctggca ctgacagaag cgccatgtat atttgaacat
    12361 tctgatgaaa ccctggagtt tctgaagttc cctgaaattg cagatatact ggaagaaaaa
    12421 tacagtgctt tattagacga tgccgtttat acggtgactt atgcaaaatt agtcctgcgg
    12481 acttattttg atgagggtca gaaattagcg gcagagccgg tctggtattt tgaagtaaca
    12541 gacggtactt ctatggaggt tgctttgctt aatgcggtta caggaactga aattttcctg
    12601 aattagcaac gcttgtcata ccagattttg cctgagaaag agagtgtgat aattttgcag
    12661 tgttttataa attaccttcg gacagatttt cgccggcttg gaaaaagtta tcgatggctg
    12721 gctggaattg ttggtgtagt ggcaatcctg tttttttctc tggaaagcgt gttgtttcaa
    12781 aaagggcttg aaaatggaaa cgtactgtct acctatgtgt attctacaaa tatgacagga
    12841 tttctgattg catattcttt ctgcgctttt ccatttgcag gggtatatcc ggaagaacag
    12901 gagcataagt atattcgtta caatgtgata agaggaagct taaagtcata tgtactatct
    12961 aaaacaaccg ttatctatat cagttcactg agcattatga tattgggatc agttttgttt
    13021 ctgtttttgt gccgtacata tgttccgtgg acagactgga gtatagattc gtatggaata
    13081 gaattaaacg gctgttatgg aagcattctg gaagagggac atgtaatttt atactgtacg
    13141 ctgtacgcat tgaatctggg gcttattgcg ggggcattgt cgaatatggc tgccttatgt
    13201 tctgtgttta tatcaaatac tgtgctggtt cttgtctttc cggtactggc atttcgcgtt
    13261 ctggtatctg tgaatatagc tgattacaat atctacgctt tttatgcgta tacgaaaata
    13321 tttgcaagtg acggagtaaa ccttttgttt ctgacggtta tatcagtggg catttccgct
    13381 ctatcagccg cggggtgcta ttgggggctg aaaaagaaaa tgtagcggag ggaggactat
    13441 atgaaaacat taaaatacat aatgaaaact tctgcgcaaa aaatatttaa tgttaaattt
    13501 gcgactttct gcgcggcgtt tttaatcttg tcgtggacgt atgatcagcc atatttacag
    13561 tttgttaagg aaaaaaatta tccgatttca tggtgcattt ttccttttta tatgtcctca
    13621 tttggaattt tatctatttt ttatgtagga attgtttata ttcattctga tgttccattt
    13681 atgcagcata ttaatatgta tcaggtaatc cgtaccggga gggaacgctg ggcactcagc
    13741 cagattgccg gtatcctgat aaggtctttt tttgcagtta tcctgtctgc aatcgcagct
    13801 gttcttccgt tttggggaca tatagaattt tcgacagact ggggaaaagt tataaaaacg
    13861 ctcgcttcgc aaagagcaga tgagggattt ggatttggaa tggggcaaat gcttgatttt
    13921 cgcttccatt atgggattct tgggaaattt acgccggtac agcttatgat aattactgtc
    13981 ctgatatgta cattgatatg tacgtttctt ggcattttga tgtttcttat cagtttgtat
    14041 gccggtaaaa tccttgcagt cgcagtgaca atgatgagtg tggttgcatt atttattgtg
    14101 gagaatatat atggggaatg gaaactgatt gtggcgcatg ttgtacctac atactgggcg
    14161 gaggtggcat taagcgcgac gcctgtcagc ggacgttatc gaatcccttc cctgacatat
    14221 atttttacat ttttaattgt tgcggttgtt ttcatgtctg tgataatttt ctgtaaagta
    14281 aaacatacag agtttcactg ggaaaatgag gacgcgtagc ttacagacag gaggacagga
    14341 cagatggaaa aacagaggat tgaagtaaat catgtattta aaagctttaa ggaaaaagaa
    14401 gtgttaaaag atgtatcgct gacctgtgaa agcggaaaaa tatacggaat cgtaggacat
    14461 aacgggtctg gcaaaaccgt acttttcaaa tgtatctgcg gattttttta ctgtgacaga
    14521 ggagaaatca gagtaaatgg gaaatgtatg gggaaagatg ccgacatgct gcagaatgcc
    14581 ggaattatta tagaagaacc gggttttttg cgccagtgga gcgggtttca taatctggaa
    14641 tttctgtata caatccgaaa taaactgaat aaaaaataca tgtattccgt tctggaaaag
    14701 gtgggacttg aaccacgttc aaaaattcct gtaggaaaat attctcttgg tatgcggcag
    14761 cgtttagcaa tcggtcaggc gattatggaa aatccagata ttttaatact ggatgaacct
    14821 atgaacggtt tagataaaaa tggggtacag gaaatgaggg gactgtttga gcagatgaaa
    14881 aacgagggaa aactgattat cctggcaagc cataatagag aggatattga tgtgttgtgt
    14941 gatgaagtat atgaaatgga aaatggtata ttgaaaaaac gaagataatt aaaagatata
    15001 gttggaggtt agtatgataa taccatatga aatttttaag gaaaacaaaa gatttaaaga
    15061 aagtatagat aatgcccaga atgagacaga tatattgttg tataatgcgg ctaaagaata
    15121 tagtaatagt gtgaggaaaa gggcaaaagc ggtaacggat ataatcatgg aacgaattga
    15181 aaaagagatc aagaacagtt aaacaaaata agtggcatct gtcaaaatga taccattata
    15241 tatccttgcg ggtcattttt ccggacatca atggtgtcag ggaaagagct gagtaatcat
    15301 cttccgtaaa agctggtagt gtaaaatagt ttgtgttttt ggtaaaaaat aactcctttt
    15361 tggtaagaa
//
