LOCUS       gnlProkkaBNKOPIDN_176  13688 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BNKOPIDN_176.
ACCESSION   gnlProkkaBNKOPIDN_176
VERSION     gnlProkkaBNKOPIDN_176
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:31:13
            Original ID  :: gnl|Prokka|BNKOPIDN_176
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13688
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13688
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1435:4129]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1436..4129
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..13688
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13688
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             complement(328..558)
                     /locus_tag="ctg168_1"
                     /transl_table=11
                     /translation="METTVMNVAVSQGIWAVLAVFLLIYIVKSNEQRDTKQEEREKNYQ
                     TVIESLTEKFQILNQVQSDLKEIKDNLFNKN"
     CDS             859..1383
                     /locus_tag="ctg168_2"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILRYISENK"
     CDS             complement(1436..4129)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     762.3; E-value: 1.3e-230)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg168_3"
                     /sec_met_domain="DUF4135 (E-value: 5.7e-94, bitscore:
                     304.9, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.4e-52, bitscore:
                     168.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLKLDYLCRKNRTMFLKILILDVHRQKNFGNLKGSTPKEQYDYY
                     EKKYLNNATYVKSLLQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRK
                     FSGTVGIYMSKGDTHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGIS
                     CRTVQYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAH
                     GEYPVIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNS
                     RVLISAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYT
                     ECIIRGFCRAYMVTMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRE
                     CRKALLNVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLP
                     CTPYESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIY
                     SQIRKIVHRICSRAIIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLH
                     DFEEKNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLT
                     GKRVWMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADME
                     KDLWKKGQETGNGYGWRLKGTDGPLAGMSHGNSGFLMAYAALYECNHKAEYADKIQLLL
                     RYEDSLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLN
                     AADSLFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAK
                     ISGTEYLNLAFMNGISGTGMALMEIL"
     CDS             complement(4120..4248)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg168_4"
                     /transl_table=11
                     /translation="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYGTIVCC"
     CDS_motif       complement(4138..4248)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /locus_tag="ctg168_4_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4120..4137)
                     /prepeptide="core"
                     /locus_tag="ctg168_4_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="519.7"
                     /monoisotopic_mass="519.2"
                     /core_sequence="TIVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /leader_location="[4137:4248](-)"
     CDS             complement(4265..5746)
                     /locus_tag="ctg168_5"
                     /transl_table=11
                     /translation="MLKVLLYGLATFMETGIGVWIFSQTFSERRILEKKYYVLEWLLYS
                     LIFFGIYNFSVSLWQIDKKIEKYVIKVICIYIIGLIAGIIYDIFFVKKKEMVLRRILYI
                     GMIFWLTAQYWAGYQSLLMIILGSGIIVLYVFCYFDCTFKQAYVWNFFYAVNIGLIKEA
                     YVVYAGVFNHKQWDDFYSYPRGHTYQEVIFWILGCLFIFWIIKFILSVNSIKGILRTRL
                     KELFIIGLLEYVLLIVSIIYKFGTIKKENFVMTACLLAVSNIALIGVYVKFQKKTLEMR
                     NQILDMRCKLMEEEYEELRMSYDRYRCLVHDEKHLLLYIKECLENGELDSCITFLNHYK
                     RESIRYSGVAWTGIPEINFMLNIKVRKMEEKNIFFKVDSKIEKIPMKDIDFVVLLGNLL
                     DNAIEAAEKCEEGKGKITCIFRNINDMFIFKVKNTSIYKPYEKNTKFYTSKKEKDEHGW
                     GIESVKQIVRKYNGEIDFKYDKDFFEVEIIISDNT"
     CDS             complement(5750..6457)
                     /locus_tag="ctg168_6"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKDITEQYFAEKNVDCTVTIYQNVEWFLL
                     GLNEEKFDMYILDIRMPGENGIEAAREIRRLYPDPVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKEKLPQAYDALLPGIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTVEKELNSKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGV"
     CDS             complement(6463..7017)
                     /locus_tag="ctg168_7"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTIREILKKTGKTREDFFPKGYLLGKRIKLTKSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKGDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             7136..7471
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.6; E-value: 4e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg168_8"
                     /transl_table=11
                     /translation="MKNNTIGKRIAEARINRNITQEHLEELSGLSVSTISRIETGKYMP
                     TIENLLKLSEILDVGLDYFLYDLLPHNKDIQSPAIQDAISIMNQMGERQTEYIVKILKI
                     YQASHQD"
     CDS             7659..8552
                     /locus_tag="ctg168_9"
                     /transl_table=11
                     /translation="MTKTEKAVTWAIRIANDPAHGYDQDNRWGPDYDCSSLVISAWQQA
                     GVPVKTKGATYTGNMKSVFLSCGFKDVTSKVNLSTGSGMKRGDVLLNIASHTVMHIGNG
                     QVVSASKNENNGYHGGKPGDQSGKEIKLQSYYNFPWDCVLRYTEDSSTTDPDPEPQPTA
                     GNAKIRKGQGYANKFANAGISITGKRDAATKKAGVKVLQTALNRDYGAGLDVDGIWGTN
                     TDNALGQHYVKNGETQYMVTAAEILLLLRAYDPNGVEIPGTFGSGLLSAVKAFQKAQGL
                     TVSGTCDRNTFLKLIS"
     CDS             complement(8698..9456)
                     /locus_tag="ctg168_10"
                     /transl_table=11
                     /translation="MKQKKIAIIMAGILAAAAAMTGCAEQNKTETQVDYTQNSQEKSEQ
                     TKQKTAEKSQPDKKQVNKSTSIGKEDSNQTADKKTKISASSNNAGDVQNSENGTDSTAG
                     TDTDDSQTTGVDTSASEDNGSTGNGGTQSDQRADQAMIYDSEGNGRLISEADDGNWYDS
                     DGNYYGSWEDIEDAMVNENGVTDQDGNKYYWTAPHDASEEVTDPYDLYSWDPGTNSYIP
                     FQAAESDCSPVGRGNGWYYYDEDSGEYVPW"
     CDS             complement(9696..12377)
                     /locus_tag="ctg168_11"
                     /transl_table=11
                     /translation="MKSNYKIFTAVFLSAIMTAAAPLTVCGAEVFSAGESFSDGTGSIP
                     AILTDMVLPGGEIGTEYQVQLEADTDVSWSLEEGSELPAGLTLSSGGVISGTPQKEGSF
                     SFTVQADNGIGVSSQELSLYVAQREQEPVIKQYELTSGTALINLGIHAEGEQSRKRLFL
                     YNAGTDSLHLSDFPQSRYFDFSYAPIFDTNTDEEMQPGSCAAVDIDDKKNLPAGNYEET
                     VTFETKEGASCKVTLKVIVGASSEKDYELSIETGTEEEFTESDFYDPEFRVEKYVVVRN
                     SGKKETRIRIDTSGLKNFEVDDQMAKWTEDYEEQDSKKLLKPGETLYFYILPKQEYGIY
                     DETFAFLADDGSRYPLHVTMNREKNPTEKKQLEITEKSAGGFPTMQWGYKTLPEAKTYI
                     LKNVTDTDMKLSFNRSKECSVLLSGNAYLAPGESTELRLWPKLGLSVGKYSFQVTVTAK
                     TVAGEHLTTQNLYNSFIVGDRTYQGLADAVAPVTGITNGAEKTADALHLPKSLEVYGAE
                     VNGEKTTFSASVKWDVENCAYDPKSKAAQSFLVNGSLELNEDENNEGLDTAVQIMVQVD
                     AYQTLNRPVIDTRWTRVITNYAMLYLRDLSNEADGYQFVTAKSQKDLKKGNYTAQTKIT
                     NSELNQYPELKYIPEGTHSLYCRAYKENSSHVMEYGEWSDGVPVTVKAKTPDAPVVQKV
                     QVKKNDVRIVLNSKGEEPDGYDVVAARSKNGKEPSDYIKVKSGYSGSSKELILRGVPAG
                     TWYIGVHAYKYLNGSNTKVLSKWAEVRKVTVKTSLVTGKPAVKSAKVSRQGTKRNVAVT
                     FTVPKSCDGTDWVLAKKVSKSDNGSYTGVSSYAYTKKNQTKTTVVFKNVKPGVYYLAGR
                     AYVKGYAKSYTKWSKIKKIVVK"
     CDS             complement(12572..13540)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 214.8; E-value: 3.4e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg168_12"
                     /transl_table=11
                     /translation="MKLGILGAGGIASTMAKTVAGMKDVEAYAVAARDLERARVFAQKY
                     EVKKAYGSYEEMLADDEVGLVYIATPHSHHYLHAKMCLEAGKHVLCEKAFTVNAEQAQK
                     LFDLAKEKKLLITEAIWTRYMPSRKMINDIIESGVIGEVTAVTANLSYTVSHVERIRKP
                     ELAGGALLDVGVYPINFASMVLGDKVKDVKATAIFQNGVDILDSIAMVFEGDRMATLQC
                     GAREISDRMGSIFGTRGYMQVQNINNPEKITVFDTEHKEVASYVVPEQISGYEYEVESC
                     MKAIHEGKTECPEMPHAETIRIMKIMDDIRKSWNYEIPCIE"
ORIGIN
        1 ctatttctta tcagaaagat ttactttcca tagacacaag aatttttaca ccctcgcata
       61 aacacttgga ttgcggccat tttttttaat ctattttaca ctacccaaaa gtcaggtttt
      121 attatcataa tataccattt actatacgaa catctgtaaa tctgggatta aaagtattct
      181 aatggacacg aatgttatgc ttatattcat ctaccatttt agtaaacata tttttctcaa
      241 attaacctat tttcttacct aaaatgacag aagccctctc cgctggaaaa atatatcctg
      301 cagaaaaggc ttttttcttt tccctattta atttttgtta aaaagattat ccttaatctc
      361 tttcagatcg ctttgaacct gattcagaat ctgaaatttc tcagttaaac tctcaatcac
      421 cgtctggtaa tttttctctc gttcttcctg ctttgtatcc ctctgttcat ttgatttcac
      481 aatgtaaatc agaagaaaaa ccgcaagcac agcccagatt ccctgtgaaa ctgccacatt
      541 cataaccgtt gtttccatgg tttctgcctc cttccttaat cttcttttat tatgcaaact
      601 ttttctatgt tttgtctact aaaagtcttt tctaatctta ttattaccgt tttaatttaa
      661 agcatatttc tattctctac aattattttg caaatctctt tttaccatgt atttcttctc
      721 ctatcgctga tctaaatttg caacctcact taataaagag ttttttctct tccatttgta
      781 aactcacaaa tttttttctt ttttagtttc tgatcagcag ttttcttact acttccccta
      841 aaaaggaggt agatacctat gaaaacactg acagaactta tccaaaatta tcaaaatggt
      901 atcccagatt cagacagtga aattctcaaa cgtatggaac cgcttgtgaa aggatatgca
      961 tcccggattc actgcatgga acgcgaagat tccacacagg aattgtatct tactttgtta
     1021 aagacattgc catatttaag ttcttcatcc tcagaaggtg aatgtatcag atacatgcag
     1081 acctctgtcg aaaacagata tcgttccctt tgccgcagtt gtctttccga acctgaaaaa
     1141 gatgattttg attcttgttc tgtttcatta caggctcccg acagttttga tgacacctat
     1201 tatgatgtaa ccgcatatat caactcttac ccttcggaca gtgtccagag aaaaattctg
     1261 tccatgtact tttatcagga taaaagcgat gcccagattg cccggaaact gaagctgtcc
     1321 cgccagtacg tcaatcggat gaagaagaaa ctaattctca gatatatttc cgaaaacaaa
     1381 taaaagaaac acctgctgac cataaattta cagtctgcag gtgttccctt agttttcata
     1441 aaatttccat taatgccatt cccgtaccgg aaatgccatt cataaaagcc agattcagat
     1501 attctgtccc agatattttt gccgggtgat ccagttgaaa taaaaggcag tcacataacg
     1561 cctcatattg ctccttcatt tttttattac catattttcg aaggtacttc ttcataataa
     1621 gtaaattccc ggacatccca tgacacagac aaattttttc atcctgttct ccataaaaca
     1681 aagagtctgc agcatttaac ctgtcttttt taatctgcat atcctcagga aacagctctt
     1741 ccagtttcat tcgtgaaagc aggattcccg gcgccccatg gcaccatgca ttcatgaagc
     1801 tttcccctga actctctcgt aaatccttcc agtttccggc tttctctgag tacagagaat
     1861 cctcatatct cagcaaaagc tgtattttat cagcatattc cgctttatga ttacattcat
     1921 acaacgctgc ataagccatc agaaatccac tgttgccatg agacattcca gccagcggtc
     1981 cgtctgttcc ttttaatctc catccgtatc catttccggt ttcctgtcct ttcttccaca
     2041 aatctttttc catatctgcc gctatttcat aatatttcag atttccggtt tctttatata
     2101 acatcactgc cactacaata gctccggcat ttccgctcag ataatccagt tgtgaatctt
     2161 ctttccatac cctctcaata atgctgaaat gcttttccgc ataaatcatc cacactcttt
     2221 ttcctgtaag tttaaacaga taaagatagg tatataccac cgagctttct ccatttacaa
     2281 tacctgtcag aagattttta tcataaatct gttttttgtg tatttcatct gtataagctt
     2341 tcaatctcaa aacagcaaga tgataaattt cttctgcact tgcattcttt tcttcaaaat
     2401 catgaagata ttttgcaaga aacaagacta tcccggatat tccatcatat aaatatattc
     2461 cacctgatct gagattccag tgaccattat cccagaattg cagacccgcc cagccggcgc
     2521 tctgttcccg gataattgct ctgctgcaga ttcgatgaac tatctttctg atctgactgt
     2581 atattttgcg ctctttatct gtgtcatatc cctttatcct ggtcggaaac atctttttct
     2641 ttccatcaga tgccttcagc atttccatgg acagcctgat ataatcacac tgacattcca
     2701 tatcagagta actcatctgc ttcatatgca ttcgccatga ctcataagga gtacagggca
     2761 gatattcttt atgttctccg ccatttccat cataaacaga tctgctgttc gcatcaatct
     2821 caaagcaggg tatatccatt tccagaaggc tgtcaatttc ataatcatga atctctttca
     2881 taaaagaaga ttccccctct ttgtgaatca cattcaaaag agctttcctg cattctcttg
     2941 acttcatata atccggatga aacgaagcca taagatacat tgcatactgt tgggtatgcc
     3001 gcagtacaac tctggaacgt ccgtcaaaaa agccggacaa catcacctcc actttcttat
     3061 ctgccattgt caccatgtac gctctgcaaa atcctctgat aatgcattcc gtataatctg
     3121 ccgcattgat aacctgatca tttagtctta caatgcattc ctttatctgc atttccacag
     3181 gttcatattc tatgtgaata tcagatgttt tatcatcctt taccacagga agtttaaacg
     3241 gcgtttttat cttttcctct gttcccattg cacttataag aactctgctg tttcctctgc
     3301 cccatgtgag aacagggagc attcctgtat gtataaccga atttgccaat tttatttctg
     3361 tacttttgtt tattttttct tctacactac ttccgtcttt ttctgattgt tgttttaaat
     3421 atcccggata cgtttccata tcgataatca caggatattc tccatgtgcg ataatatttt
     3481 caccatgaag atctgttgct ccaagggcat atcccaaaaa cagatgtatg cccattctga
     3541 aataataatg ctccacctca ctttcgtttt tacagggaat attctcaatt ttttcttccc
     3601 atccatagga atcatgagat aaatattgta ccgtcctgca ggaaattcct gtttttctgc
     3661 ataaatagtt ataaagttcc tgatatttta tattcttatc aagactatgt ggcttatagt
     3721 acagaattgt tccattatcc aattctacct tcgccacact tcgtcctcct ctgtgtgtat
     3781 cgcctttcga catgtaaatt cccacagtcc cggaaaactt tcttccatca cagaatattt
     3841 tttgtatctg ttctttttct gcataaagag atttcctgat ttcacattct gctctctgga
     3901 tagagttatt ttttaattca agcagacgtt ttaactcggg atattcctgc agtaaagatt
     3961 ttacatatgt tgcattgtta agatattttt tttcataata atcatattgt tcttttggcg
     4021 tacttccttt tagatttcca aaatttttct gccgatgtac atctaagatt aatattttaa
     4081 gaaacatagt tcgatttttt ctgcataaat aatccaattt cagcaacaca ctatagttcc
     4141 atatacaata aaagacaatt tctcttctat actttccgta tctattatct ctatttcatc
     4201 taattctttt tccacatttc ctattatttt atcattcatt tcgttcataa ccgtcactct
     4261 cccattatgt attatcgcta attattattt ctacttcaaa aaaatcttta tcatatttaa
     4321 aatctatttc accattatac tttcttacaa tttgtttgac actttcaatc ccccatccgt
     4381 gctcatcttt ctctttttta cttgtataaa atttagtgtt tttttcataa ggtttatata
     4441 tgcttgtatt ctttacttta aaaataaaca tatcattaat atttcgaaaa atacacgtaa
     4501 ttttaccttt tccctcttca cacttttcag cagcttctat tgcattatcc aaaagatttc
     4561 ctaggagtac aacaaaatct atgtctttca tcggaatttt ttctattttt gaatctactt
     4621 taaaaaaaat attcttttct tccatttttc gcacttttat attcaacata aaatttattt
     4681 ctggaattcc tgtccacgct actccactat atctaatgct ttctctcttg taatgattca
     4741 aaaaagtgat acatgaatcc agttctccat tttccaggca ttcttttata tataaaagca
     4801 aatgtttttc atcgtgcacc aaacaccgat accggtcata tgacattctc aattcttcat
     4861 attcttcttc cattaatttg catctcatat ctaaaatctg atttctcatt tctagggtct
     4921 ttttttgaaa cttaacatat acaccaatca atgctatatt actaactgct aataaacatg
     4981 cggtcattac aaaattttcc tttttaatcg taccaaattt gtatatgatg ctaactatta
     5041 ataaaacata ctctaacaat ccaataataa aaagttcctt cagacgtgta cgcaatattc
     5101 cttttatact gtttactgac aaaataaatt taattatcca aaatatgaat aaacagccta
     5161 aaatccaaaa tataacttcc tgatatgtat gtcctctcgg atatgaataa aaatcatccc
     5221 actgtttatg gttaaacacc cctgcatata caacataagc ctcttttatc aatcctatat
     5281 taactgcata gaaaaaattc caaacatatg cctgtttaaa tgtgcaatca aagtagcaaa
     5341 aaacatataa tacaattatt ccactcccaa gaataatcat taacaacgat tgatatccag
     5401 cccaatactg ggcagttaac caaaatatca tgccgatata taatattctt cttaagacca
     5461 tctccttttt ctttacaaaa aaaatatcat atataattcc tgcaattaat ccaattatgt
     5521 atatacaaat aacttttatg acatattttt ctattttttt atcaatctgc cataatgaaa
     5581 cagaaaaatt ataaattcca aaaaaaatca aagaatacaa cagccattct agaacataat
     5641 attttttttc taatattctt cgttcagaaa acgtctggct aaatatccag acacctatcc
     5701 ctgtctccat aaacgttgcc agtccataca ataaaacttt cagcattctt catacccccc
     5761 agtaattcag aattgcttct ctgacacctt tgaatctttc tctgccaact gtaataatat
     5821 taccgtcccg catataaaga tcccttcctt tcatcttcat cacatgttgg atgtttgcaa
     5881 gatatcctct gtcagatata ataaattctt ttgaattcag ttccttttct actgttgaca
     5941 gacttgctct gatctttact tccccacgcc tgtgcacaaa aatgacatat tttccttctt
     6001 ttttcatata gaaaatatca gaatatgcca gtttttcaac ttcatttctt ttatttatga
     6061 tatagtaccg ctcttctttc tccataattc caggaagaag cgcatcataa gcctgcggaa
     6121 gtttttcctt cagacactct ttggggatat aacgataggt gtttacctca tatgcttcta
     6181 ttgcataatc cacaaaattt gtaataaata taataaccgg atccggataa agtctgcgaa
     6241 tttccctcgc tgcctctatt ccgttttctc caggcatccg gatatccaga atatacatat
     6301 cgaatttttc ttcattcaat cccagcagaa accattccac attctggtat atcgttaccg
     6361 tgcaatctac gtttttctct gcaaaatact gttctgtgat atccttttct tttttcagat
     6421 acatttcgtc atcatccaga atcattattc ttatcatagc aattattcct ccatgaatgt
     6481 ataaaatctg aatttcttca catcataaaa ataactttca tccttattga tgaccagctc
     6541 ataaacctcg atatcccctt tggttgtcac atcagttctg tgatactgat aaatgtatct
     6601 gccttcctca tggtttttta cctttctgat gatatcatcc accagttctc cgattgtcat
     6661 cggactgtct ctggaaggtc tccatcttcc aatcatacca cgaacctgtg acttggtcag
     6721 tttaattctc tttccaagaa gatatccttt cgggaaaaag tcttctctgg tctttcctgt
     6781 cttttttaat atctcacgta ttgtcttatt ttcttcatct aaagcaaatc ccatattagc
     6841 ataagcctgc atatgaagca acgctaattc gagatattta ctgttttcag attctttatt
     6901 ccataacagt aatttgtcca gacttttata tacagtttct ctgattgtaa ttccctgatt
     6961 ttgcaaagtc tgtaaagaaa acatcatggt atacaaatcc tttgtatatt cgtccatatt
     7021 cctatattcc tcctgtcata aaacatatca aatttgatta ttcgcttgtc atttatatcc
     7081 ttatacatat ttaattccgt ctgttaaact ttatcaaagg aaaggatttt tatttatgaa
     7141 aaacaatact atcggaaaaa gaattgcaga agctcggatc aacagaaata ttacccagga
     7201 acacctggaa gaattaagtg gtttatctgt aagtacgatc agccggattg aaacaggtaa
     7261 gtatatgcct actattgaaa atctccttaa gctttctgaa attcttgatg tgggacttga
     7321 ctattttctt tatgatctgc ttcctcataa taaagatatt caaagcccgg ctattcagga
     7381 tgcgatttca atcatgaatc aaatgggtga acgccagact gaatacattg taaaaatact
     7441 gaaaatatac caggcctctc atcaggatta aatataatta caattcgaca attttcgtgt
     7501 ttttgtcctc gaaaagcatt tttctgacct cgaagcaaca atcaggaaat gctttttatt
     7561 tttttctgtt tcatgtttac atttttccct tttctcactc tttataagat gtatcaccgg
     7621 tgagcaaata aataatcaaa tttcaggagg ataaaaaaat gacaaaaaca gaaaaagcag
     7681 taacatgggc aattagaatc gcaaacgatc cggcacacgg atatgatcag gataacagat
     7741 ggggaccgga ctacgattgt tcttcactgg taatctccgc atggcagcag gctggtgttc
     7801 ctgtaaaaac aaaaggagcc acttatacag gaaatatgaa atccgttttt ctgtcctgcg
     7861 gctttaagga tgtaacttcc aaagttaatc tcagcacagg aagtggcatg aaacgtggcg
     7921 atgtattatt aaacatcgca agtcatacag taatgcacat tggtaatggt caggtggtat
     7981 ctgccagcaa aaatgaaaat aatggatatc atggtggtaa acccggagat cagagcggaa
     8041 aagagatcaa acttcagagt tattacaatt tcccctggga ttgcgttctc cgttatactg
     8101 aagattcttc aactactgat cctgatcctg aacctcagcc aactgcagga aatgcaaaaa
     8161 tccgcaaagg tcagggttat gccaataaat tcgccaatgc aggaatctct attaccggaa
     8221 aaagagacgc tgctaccaaa aaagcaggcg ttaaagttct tcagacagct ctgaacaggg
     8281 attatggtgc cggtctggat gtagacggta tctggggaac aaacacagac aatgctcttg
     8341 gacagcatta tgtaaaaaat ggtgaaacac agtatatggt aactgccgct gagattctcc
     8401 ttcttttacg tgcttatgat ccaaacggtg tagagattcc cggtaccttt ggctcaggac
     8461 ttctctctgc tgtaaaggca ttccagaagg cacagggctt aacagtttcc ggaacctgtg
     8521 acagaaatac tttcctgaaa ctgatcagct gatctttacc agataaacat ccggcagaat
     8581 tctgtcccct gattctgtcg gatatacccc ttcactattc atgtatataa caaaaagaag
     8641 caattttgaa acccattaaa atggtctcaa aactgcttct tttcgcattt ttatattcta
     8701 ccacggaaca tattcgccgc tgtcttcatc ataataatac cagccgtttc ctctgcctac
     8761 aggactacag tcagattccg cagcctgaaa cggtatatag gaattggttc ccggatccca
     8821 ggaatacagg tcatacggat ctgtgacctc ttctgatgca tcgtgaggtg ctgtccagta
     8881 atatttattg ccatcctgat ctgtgacacc attttcattt accatagcat cttcaatatc
     8941 ttcccagctt ccatagtaat ttccgtcact gtcataccag tttccatcat cagcttcaga
     9001 aatcagcctt ccatttccct cactgtcata tatcattgcc tgatctgccc tctgatcaga
     9061 ttgagtacca ccattacctg ttgaaccatt atcttcagat gcagaagtgt ccacccctgt
     9121 ggtctgggaa tcgtctgtat cagttcccgc agtactgtct gttccattct ctgaattctg
     9181 tacgtcgcct gcattattgg atgaagcaga tattttcgtc ttcttatccg cagtctgatt
     9241 tgaatcttct tttccaatgg atgtactttt atttacctgt tttttatccg gctgagattt
     9301 ttctgctgtt ttttgttttg tctgttcgga tttctcctgt gagttctgcg tataatcaac
     9361 ctgtgtctct gttttattct gttccgcaca gccagtcata gcagccgctg ctgctaaaat
     9421 ccctgccata ataattgcaa tctttttctg cttcattttg ttatcctttc tacatttgtt
     9481 aaaaatgtcg atgcctttat cataatgtgc ttttcctgtt cattatgaca tacttcacag
     9541 gcttcgatgc ctcatatgtc ccttatctgt catgaaatgt accccatttt tttccaaaat
     9601 ctttacccca taattttgcc ttataaacgc ttggtaaaag gggaatatct tttttcttaa
     9661 aagtgaaatc tctgtgaaac aaatggcagc agtacttatt tcacaactat tttctttatt
     9721 ttcgaccatt tcgtataact ttttgcataa ccttttacat aggcacgtcc tgcaaggtag
     9781 tagactccgg gcttcacatt tttaaagacc accgtggttt ttgtctgatt tttctttgtg
     9841 taagcataac tgcttacacc agtatagctg ccattatcag atttggaaac tttctttgcc
     9901 agtacccagt ctgttccatc acaggacttt ggaacagtaa acgtcaccgc cacgtttctt
     9961 tttgttccct gtctggaaac cttagctgat ttaacagcag gttttcctgt tacaaggctt
    10021 gtttttacag ttaccttcct gacctctgcc catttactga gcactttggt attgctccca
    10081 ttcagatatt tataagcatg tacgccaata taccacgttc ctgccggtac gccccgtaag
    10141 ataagctctt tactgcttcc ggaataccca ctctttacct ttatataatc cgatggttct
    10201 tttccgttct tacttctggc agcaacaaca tcgtaaccgt ccggttcctc acccttgctg
    10261 ttaagtacta ttctgacatc atttttcttc acctgcacct tctgaaccac aggtgcgtcc
    10321 ggagtctttg cctttaccgt aaccggaacc ccgtctgacc attccccata ttccataaca
    10381 tggctgctgt tctctttgta tgccctgcaa taaagactat gtgttccctc cggaatatac
    10441 ttcagctcag gatattgatt cagttcagaa tttgtaattt ttgtctgcgc agtataattc
    10501 ccctttttca gatccttctg agatttcgct gtcacaaact gatagccgtc cgcttcattg
    10561 gaaagatctc tcagataaag cattgcataa tttgtgatca ctctggtcca ccgcgtatca
    10621 ataactggtc tgtttaatgt ctgataagca tccacctgta ccattatctg tacggcagtg
    10681 tccagccctt cattattttc atcctcattc agttccagag atccgttgac cagaaaactt
    10741 tgagctgcct tgcttttcgg atcataagca caattctcca catcccactt cacagacgca
    10801 gaaaatgttg ttttctctcc attcacctcg gcgccataga cttccagcga cttcggcaga
    10861 tgcaaagcat cagcagtttt ttctgcacca ttggtaattc cggtcacagg cgcaacagca
    10921 tctgccagtc cctgataagt ccggtctcct acaataaaag aattatacag attctgcgtt
    10981 gtcaggtgtt ctcctgccac tgttttcgca gtcacagtca cctgaaaact atattttccc
    11041 accgaaagcc ccagtttggg ccagagtctc agttctgtgc tctccccagg tgccagataa
    11101 gcatttccag ataataacac actacattct ttactacggt taaaagacag cttcatatct
    11161 gtatcagtaa catttttcag aatatatgtc tttgcttccg gaagtgtctt atagccccac
    11221 tgcattgtcg gaaaaccccc ggcagacttt tcagtaattt ccagctgctt cttttctgtc
    11281 ggattcttct ctctgttcat tgtaacatga agaggatatc tgcttccgtc atctgcgaga
    11341 aatgcaaacg tttcatcata aattccgtat tcctgcttcg gcaatatata aaaataaagc
    11401 gtttctcccg gtttcagcag ctttttggaa tcctgttcct cataatcttc tgtccacttt
    11461 gccatctggt catccacttc aaaattctta agaccagaag tatctatccg tattctggtt
    11521 tccttttttc ctgaatttct gaccactaca tacttctcca cacgaaattc cgggtcatag
    11581 aaatcgcttt ctgtaaattc ttcttctgta cctgtttcta tactcagctc ataatctttt
    11641 tcagaggaag ctcccacaat tactttcaga gtaaccttac aggaagcacc ctcttttgtc
    11701 tcaaatgtca ctgtctcttc ataatttccg gcaggcagat tcttcttatc atcaatgtcc
    11761 acagccgcac aacttccggg ctgcatttct tcatccgtat ttgtatcgaa aatcggtgcg
    11821 taggaaaaat caaaatatct gctctgcgga aaatcagaga gatgaagcga atctgttcct
    11881 gcattataaa gaaataaccg cttacgtgac tgttctccct ctgcatgaat tcccagattg
    11941 atcaaagcag tacctgatgt cagctcatac tgctttataa caggttcctg ctcacgctgt
    12001 gcaacataaa ggctcagttc ctgtgaagaa actccaatac cattgtccgc ctgtacagta
    12061 aagctgaaac tcccttcctt ctgcggtgtt ccgctgatca ctcccccgga agacaacgta
    12121 agtcccgccg gaagctcgct tccctcctcc agactccagc tcacatctgt atcagcttca
    12181 agctgtacct gatattctgt tccaatctct ccacccggca gaaccatatc tgtcaatatg
    12241 gcaggaatac tccctgttcc atcactgaaa gattctcccg ccgaaaaaac ttccgccccg
    12301 catactgtta acggagctgc tgctgtcata attgccgata aaaaaactgc tgtaaaaatt
    12361 ttgtaattac ttttcattct tctcctccag ataataaaat ataaaagtat caatttacct
    12421 aattaatatt aatataccac tggacgggaa tgtttctgta attacggaat gacatgttgt
    12481 ctaatggtca tgaatatcag aaaagccagt aatgtttcgg gtatatgtca aaaacattac
    12541 tggtcttttt tataagatta ttccacactt tttattcgat acagggaatc tcataattcc
    12601 aggatttacg gatgtcgtcc atgattttca tgatccttat tgtttccgca tgaggcattt
    12661 ccggacactc cgtttttccc tcatgaattg ctttcatgca ggattctacc tcatattcat
    12721 atcctgagat ctgttccggc acaacataag aagccacttc tttatgttcg gtatcaaaca
    12781 ctgtaatctt ttccggatta ttgatattct gcacctgcat atatcctctg gttccgaaaa
    12841 tacttcccat tctgtctgag atttctcttg ctccacactg aagggttgcc atgcggtctc
    12901 cctcaaacac catggcaatg ctgtccagaa tatccactcc attctgaaag attgcagtag
    12961 cctttacatc ctttacctta tcgccaagca ccatggaggc aaaattgatc ggatatacgc
    13021 ctacatccag aagagcacct cctgcaagct ccggtttacg gatacgttcc acatgactta
    13081 ctgtatagct gagattcgcg gtaactgccg taacttctcc gatcacacca ctttcaataa
    13141 tatcgttgat catctttctg gacggcatat atcttgtcca gattgcttct gtgatcagaa
    13201 gctttttctc ttttgcaagg tcaaataatt tttgtgcctg ctctgcattt acagtaaatg
    13261 ccttttcaca aagcacatgc tttcccgctt ccagacacat tttcgcatgc agataatggt
    13321 gtgaatgagg agttgcgata taaaccagtc caacctcatc atctgccagc atttcctcat
    13381 aggatccata tgcttttttt acttcatatt tctgtgcaaa tacccgggca cgttccagat
    13441 cacgagcagc aaccgcatac gcctccacat ctttcattcc tgccactgtt ttcgccatag
    13501 tagaagcaat gcctcctgct cccagaatac ctaacttcat tttactgtcc gttactgaaa
    13561 acttataaaa agttataaac ttctatgttt cattcctact tcaacgagta tgcttttgat
    13621 gatataaata tctatctact cacaagttct tgtactctcc ataggcgtaa attccggact
    13681 aacgtatc
//
