LOCUS       c00102_gnlPro..        10576 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BNKOPIDN_110.
ACCESSION   c00102_gnlPro..
VERSION     c00102_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:57:45
            Original ID  :: gnl|Prokka|BNKOPIDN_110
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 188
            Orig. end    :: 10764
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1272
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_1"
                     /sec_met_domain="HGD-D (E-value: 1.1e-55, bitscore: 181.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWEAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLWPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERAFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     protocluster    1..10576
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[188:3132]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..2944
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..10576
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10576
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             1265..2944
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_2"
                     /sec_met_domain="HGD-D (E-value: 6.7e-17, bitscore: 53.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 4.8e-65, bitscore:
                     211.3, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPEGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDEKGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
     CDS             3448..4863
                     /locus_tag="ctg102_3"
                     /transl_table=11
                     /translation="MWEAINSFLTTVDNLVWGVPLMVLIMAGGILLTARLGLLQMRRLP
                     LALKWMFKNEEEGDGEISSFAALCTALSATIGTGNIVGVATAVCAGGPGALFWMILAAF
                     FGMATKFSEGLLAVKYRVVAEDGHSLGGPFYYIEKGMGTKWKWLAKIFAFFGVCVGLFG
                     IGTFSQVNGISSAVQNFFDPNKSNCVNIPFLGEYSWAVVISSLILAACVAAILIGGLKR
                     IATVSQIIVPFMAVIYLIFSVALILLNITEIPAAIVTVVKGAFNPSAVTGGVVGTMIVS
                     MQKGVARGIFSNEAGLGSAPIAAAAAQTKEPVRQGLVSMTGTFIDTIVICTMTGLSIVL
                     TGAWQVEGLEGVQVTTYAFQHGLPIPGQISAFVLMICLVFFAFTTILGWDYYSERCLEY
                     LTNGHKKTILTYRWLYILAVFIGPYMTVSAVWTIADIFNGLMAIPNMIALFALSGVIVK
                     ETKAFFAAEKHKM"
     CDS             5175..6086
                     /locus_tag="ctg102_4"
                     /transl_table=11
                     /translation="MIYTVTFNPSLDYIVSVDDFKLGLTNRTSSELMLPGGKGINVSTV
                     LMNLGIENTALGFTAGFVGKKIIRRLHEMGVKSEFIQISEGVSRINLKLKSIDGTEING
                     AGPVISKDKVEELMKKLEELGEGDVLFLAGSIPSSMPDDMYEQIMARLDGKGVMIVVDA
                     TKDLLVNVLKYHPFLVKPNNHELGEIFGVELKTRKDVIPYGKKLQEKGARNVLISMAGE
                     GAVLVAEDGQVFEEPAPKGRLVNGVGAGDSMVAGFVAGWMEKKDYEHAFHMGIAAGSAS
                     AFSENLATKEEIEAVYRQITEK"
     CDS             6104..8017
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg102_5"
                     /sec_met_domain="PTS_EIIC (E-value: 7.6e-21, bitscore:
                     66.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRITDLLDRRSVSLTAAPKTKSETLDMAVDLMVKSEKISDREAYR
                     KQVYLREEESTTGIGEGIAIPHGKCDAVKKPGLAAMVIKNGVEFEALDDEPVTLLFLIA
                     APNTEDNIHLDVLSKLSVMLMDEEFTESLRNASSVDEFMDIIDRADSEKKDIDERLADT
                     GSAEGTQAKILAVTSCPTGIAHTYMAAEGIEKAAKAKNCFVKIETRGSGGAKNVLTDQE
                     IADADCIIVAADAKVPMERFDGKKVIECQVSDGISKADQLIDRAINGDAPVYHAAAGSQ
                     TSSAGNKSGGSVGHKIYMQLMNGVSHMLPLVVGGGILIAIAFLIDGLSVDLSALPADQR
                     ANFGTITPVAALFKGIGNTAFGFMLPILAGFIAMAIGDRPALALGLVGGMMAANGKSGF
                     LGALLAGFAAGYIILGLRKLCDKLPEALEKIAPVLIYPVVGILIIGLLMTFIVEPVMGG
                     INTGLNNALTGMGSSSKVILGIVLGGMMAIDMGGPFNKAAYVFGTAAIAAGNYDIMAAV
                     MIGGMTPPCAIALATLLFKDKFTKEERDAGPTNFIMGLAFITEGAIPFAASDPLRVLPS
                     CIVGSAVAGAISMAFDCTLMAPHGGIFVFPVVGNAVMYLVALVVGTVISAVLLGLLKKK
                     AA"
     CDS             8077..8334
                     /locus_tag="ctg102_6"
                     /transl_table=11
                     /translation="MKEFKYVVTDNEGIHARPAGELVKLVKGFESTISIEKEGKKVDCR
                     KLLALMGLGVKKGHEVTFTIEGADEEAAYEAVSKFMQDNL"
     CDS             8629..9372
                     /locus_tag="ctg102_7"
                     /transl_table=11
                     /translation="MLTEQRFDIILKLLEEKKSVTVTELRELLDASESTVRRDITALDK
                     AGKLTKVFGGAVALNHKVTAYEPTVAQKSELNKEEKQKIAKYAASLITPDDFVYLDAGT
                     TTGLMLEYLAGVRAAFVTNAVSHAQTLAKMGIRVYLIGGELKSSTEAVVGSQAMQMIQM
                     YHFTKGFFGTNGITRREGFTTPDTSEAIVKSTAMKQCKDVYILTDKSKFGEVSSVTFGG
                     FTDAKILTEEIPEEYQDSKNILKVK"
     CDS             9440..10576
                     /locus_tag="ctg102_8"
                     /transl_table=11
                     /translation="MKFAHIGDLHIGKRVHDFSMLEDQRYILDQMMKIFAEQKVDGVLI
                     AGDVYDKTVPSAEAVQLFDEFITGLAKAEIPVYMISGNHDSAERLSFGAKLFESSDIYI
                     SQVYDGEMKRIVLKDQYGPISVYLLPFLKPAAVRHALQRDDINTYEEGVMAALQECEID
                     TTQRNVLVAHQFVTGADRSDSEETWVGGLDNVSAEVFKDFDYVALGHIHRPQKMGRETL
                     RYSGTPLKYSFSEADHKKSVTIVELLEKGNVRVSTVPLIPRRDMRKLRGTYMDVTAKDH
                     YTAENKMDYLQITLTDEEDVPGALQKLRTVYPNLMRLEYDNKRTRENREVQAVEVQEQK
                     SELELFEEFYELLNNEPMKEEQTEFVEKLIQDLKEVRV"
ORIGIN
        1 atggagatta ttgagacatt tggtcattat gtggaaaatc tgacggataa aaagcctcag
       61 tcagcccgcc ggctgttaaa aaccggttgg gaggcgcaga atctgaagtt ccgttacatg
      121 caggacaaga gactgatgcc tgcagacagg catcttgcaa acctgatgat ggataccatg
      181 ctgtggcccc ttcagaaacc ggaagattct gttattgtaa gtatttttac accctgcgaa
      241 atgatgcagg aggtgggatt acatccctat aatgtagaag gattttcctg ctatctttct
      301 gcaagcaaag cagagagggc atttttgcag caggcagaga atcagggaat tgcagagaca
      361 ctgtgcagtt atcacaagac atttcttggt gcagcgcaga aaggacttct gccaaagcct
      421 aaatgtattg tttataccaa cctgacctgc gatgctaacc tgctcacctt ccgtaccctg
      481 gcagattttt accaggtacc tgtatttgcc attgatgtac catggaatca gaccacagag
      541 aatgtacagt atgtggcaga tcagttaaag gatttaaaaa tatttctgga aaaaaataca
      601 ggaaaaacaa tctctgagga cagattaaag gaacgtcttg cctgcagtaa gcggactctg
      661 gagaattaca aaaaatatca gcagatgcgt gcagacagat atgtgccctc tgatctggtc
      721 acacccttgt atgcaggaat gacaaacaat atccttctgg gaacagcaga agaagagaag
      781 tatacacaga tgcttcttga agatattaag aaagcaccgg cagcgaaagg gaagcacatt
      841 tactggatgc ataccattcc attctggtcg gatgcagtgc gccaggagct ttgcttcagt
      901 gagaaagccc agatcgtagg atgtgaactt gcagaaacct gtgagccgga ttttgatcct
      961 gagaacccct ttgaagcaat ggcagaaaga atggtatatc attcactgaa cggaagtgcc
     1021 cttagaagga ttgaagccgg tatccgccat gcgaaacagg caggagcaga cggtgctgtg
     1081 tggtttggac attggggatg taaacatacg cttggtgcgg cacagcttgc aaagaagaag
     1141 ttcgaggaag ccggtctgcc ccttttgatc ctggacggtg acgggtgtga tcgaagccat
     1201 ggaggagaag gacagacttc caccaggctg ggagcttttc tggaaatgct gggaggtgct
     1261 gagaatgaat aaaacttact atgtctgtaa atatacccca attgaacttc tggaatctct
     1321 tggcggggaa tgtgagaact ttaatcatat gccggaggga tttgacctgg ccgatcaggt
     1381 ttcacatccc aatatctgcg gttttggaaa aacacttctg gaaggagtca tggaggggaa
     1441 aatcaaggaa cttgtcctgg tgagctgctg tgatactatc cggagtgtct atgacattct
     1501 gcttgaaagc ggcaagctgg attttctcta tattttggat gtgcttcact gtgacagtgc
     1561 ctgtagcaga gagcgtatgg ctgtacagtt aaaagggctg gcgaaggctt atgcacagta
     1621 caaaggcaca gagtttgatg ccggaaaatt ccgggctgct ttccatgcac aggagaaaat
     1681 cacaaagtcc catattgcag tgcttggcgc cagaatgggg caggaattat ttgaaatgac
     1741 cagtaaagct atgcctcttc ctgtagagaa tgatacctgc gtgcataacc gttctgtggg
     1801 aaatatactt ccaccggagg gtgcttcttt tgatgagttg atggactggt atgcaggtga
     1861 gattctgggg cagattccat gtatgcgtat gatggacccg acaggtcgta agaagcttta
     1921 taatgatccg tctgttgcgg ggattattta tcatacagtg aaattttgtg atttttacag
     1981 cttcgaatat gctgagatca agaatcatac agatgtacct cttttaaaaa tcgaatcaga
     2041 ttatactatt cagagcagcg gtcagcttct taccagactg gaagcttttg cagagagcat
     2101 tcagcctgaa acactggagc agaccataga tggagacaca aaaggagaga gaaaaatggg
     2161 aaaaggttat ttcgcaggga ttgacagtgg ttccaccagt acagatgtgg tgattttaaa
     2221 taaagatcat gagattgtga ccagcattat cctgcctaca ggagcaggag ctgctatcgg
     2281 agcagaccgt gcccttgcag aggcattgaa ggaggccgga ttgcagagag aagatattga
     2341 tgcgctggtt actaccggat acggacgtac agctattaaa aatggtgata agagtatcac
     2401 agagatcacc tgtcatgcaa gaggtgcgca tttcctgaat ccggaagtcc gtactgttat
     2461 tgatattggc ggacaggaca gcaaggtgat ccgactggat gagaaaggtg cagttgcaaa
     2521 ctttgttatg aatgacaaat gtgcggcagg aaccggacga tttctggaaa tgatggcacg
     2581 taccatggaa atgaatctgg atcagatgag cgaatgtggg ctggaattca aagaagatat
     2641 tacaatttcc agtatgtgta cagtatttgc agaatcagaa gttgtatccc tgatcgccca
     2701 gaataaggca acagatgata ttgttcatgg tctgaataag gcggttgccg taaaaaccgc
     2761 agctcttacc agacgtgtgg gcggtgagga gaaatatatg atgaccggtg gtgtttctaa
     2821 gaataagggc ctggtaaaga cactggaaga gaagcttgga acaaagctgg taatcagtga
     2881 caaggctcag ctttgcggtg cacttggcgc ggcgctgttt gcagctgata tggctgatgt
     2941 ataaaaatta tttaaatatc cagggatttt acaaggtgga aatctctgga atttttatac
     3001 tttttttata aaagtttaat tttctattga cgagttcaaa tttaagagct atagtatacc
     3061 acagtaacag caaattaacg aggtgaagtt tgcaggaaag aggaagccac ataaaaggct
     3121 atacccgccg aaggagtaaa actctcaggt tccctggatg cagggaagaa ctgcaaatgg
     3181 atcgtttctc tggagacacc cgttagatcg ggggccgaag gtgcaaataa cacgaattat
     3241 caatagctgc ccacaaatgg ttatctgatt cgtgtcttga atctctcagg caaaaggaca
     3301 gaggatgctt tatcatcccc gctgattcat atgaactata tgaacagtat tttctgaact
     3361 tctgattttt gaaacggtct gttattactt tgtttcccag ctgtacaata tattacactt
     3421 tttaaaagaa aaaggagatt tattattatg tgggaagcga tcaattcttt tttgacaaca
     3481 gtagacaatc tggtctgggg cgtgcccctt atggtcctga ttatggcagg tggtatcctg
     3541 ttaactgcca gacttggact tcttcagatg cgaagactcc ctcttgcatt gaaatggatg
     3601 tttaagaacg aagaagaagg cgatggtgag atttccagct ttgcagcttt atgtacagca
     3661 ctgagcgcca caatcggaac cggtaatatc gtcggcgttg caactgctgt ctgtgccgga
     3721 ggtcccggag ctttattctg gatgattctt gcagcattct tcggaatggc aacaaaattt
     3781 tccgaaggtc ttcttgcagt gaaataccgt gtggtagcag aagatggtca cagccttggc
     3841 ggtcctttct attatattga gaaaggtatg ggaacaaaat ggaaatggct tgcaaagatt
     3901 tttgcattct ttggtgtatg tgtaggtctt ttcggaatcg gtacattcag ccaggtaaat
     3961 ggtatttcca gtgcagttca gaacttcttt gatccgaaca aatcaaactg cgtaaatatt
     4021 ccgttccttg gagagtattc ctgggcagtt gtaatttctt ccctgattct tgcagcctgt
     4081 gttgcagcaa tcctcatcgg tggtctgaaa cgaattgcaa cagtcagcca gattattgta
     4141 ccgtttatgg cggtgatcta tctgatcttc agtgttgcgc tgattctttt aaacattaca
     4201 gagatcccgg cagctatcgt aacagttgtg aagggagcct ttaatccgtc agcagtgaca
     4261 ggtggtgtgg taggaacaat gatcgtatcc atgcagaaag gtgtggctcg tggtatcttt
     4321 tcaaatgaag caggtcttgg tagcgcacct atcgcagcag cagcagctca gacaaaagag
     4381 cctgtacgtc agggtcttgt aagcatgact ggtacattta ttgatacgat cgtgatctgt
     4441 acaatgacag gtctttccat cgttctgaca ggtgcatggc aggtagaagg tctggaaggt
     4501 gttcaggtaa caacctatgc attccagcat ggacttccga tccctggaca gatttctgca
     4561 tttgtattaa tgatctgtct ggtattcttt gcatttacta caattcttgg atgggattat
     4621 tacagtgaaa gatgtctgga atatctgaca aacggacata agaaaacaat ccttacatat
     4681 cgctggcttt acattctggc agtatttatc ggaccgtaca tgacagtaag tgctgtatgg
     4741 acaatcgcag atatcttcaa cggactgatg gcgattccga atatgatcgc attgttcgca
     4801 ttaagtggag tgatcgtaaa agaaacaaaa gcgttctttg cagcagaaaa gcataaaatg
     4861 taaggaatca aaagtaataa aataacagta aatcctctga ttatggaatt tatagcaatc
     4921 ctgatcagag gattttttct gcttgcattt gactgattat gactttttgt gcaaagtaaa
     4981 ccaaaatcag tcattatttt tatgaattag tttgattgac tttggatgaa tatgacagta
     5041 tactaagatc ataaacaaaa aacagtcatg aacatgcaga aaagacatga caatatgtac
     5101 ttttggaatc ttttggtgaa agtgaaataa agactccgaa aggataccaa tataaaacgg
     5161 gagggcaaga agagatgatt tacacagtga cttttaatcc atctctggac tatatcgttt
     5221 cggtagatga ttttaaactg gggctgacaa acagaacaag ttcagagctg atgcttccgg
     5281 ggggaaaggg aattaatgtt tccacagtcc ttatgaatct tgggattgag aacactgcac
     5341 ttggatttac tgcagggttt gtagggaaaa aaattatccg tagattacat gagatgggag
     5401 tgaaatctga gttcattcag attagtgaag gggtttcaag gatcaatctg aaactgaaat
     5461 ctattgacgg aaccgagatc aatggtgcag gaccggtgat cagcaaggat aaagtagagg
     5521 aactgatgaa gaaactggaa gagcttggag aaggcgatgt acttttcctg gcaggcagca
     5581 ttccatcttc tatgccggat gacatgtatg aacagatcat ggcaaggctg gatggaaaag
     5641 gtgtgatgat cgtagttgat gccacaaagg atcttctggt caatgtcctg aaatatcatc
     5701 cgttccttgt aaaaccaaat aatcatgaac tgggcgaaat cttcggtgta gaattaaaaa
     5761 caagaaaaga tgtaattcct tatggaaaga aacttcagga aaaaggtgca agaaatgtgc
     5821 tgatctccat ggccggcgaa ggtgcagttc tggtagcaga ggatggacag gtatttgaag
     5881 aacctgcacc aaaaggcagg ctggtaaatg gtgtgggtgc aggagattcc atggtagcag
     5941 gattcgttgc aggctggatg gagaagaagg attacgaaca tgcattccac atgggaattg
     6001 cagcaggaag tgcaagtgca ttttctgaaa atcttgcaac aaaggaagaa atagaagcgg
     6061 tttatcgtca gataaccgaa aaataataaa gggggaagaa gagatgagaa taacagacct
     6121 gcttgacaga cgaagcgtat cgttaacagc tgctccgaaa acaaagtcag aaactctgga
     6181 tatggcagtt gatctgatgg taaagagtga gaagatcagc gaccgtgagg cttatcgtaa
     6241 acaggtatat ttaagagaag aagagagcac aacaggtatt ggcgagggaa ttgccattcc
     6301 tcatggtaaa tgtgatgcag ttaagaagcc gggacttgcg gcaatggtca tcaaaaatgg
     6361 tgtagagttt gaggcactgg atgatgaacc tgtaacctta ttattcctga tcgcagcgcc
     6421 gaatacagag gataacattc acctggatgt actcagcaag ctctctgtga tgctgatgga
     6481 tgaggagttt acagaatctc ttcgcaatgc atcgtctgta gatgagttta tggatattat
     6541 tgacagggca gacagtgaaa agaaagatat tgatgagaga ctggcagata ccggatcagc
     6601 agaaggaaca caggctaaga tccttgctgt tacttcctgt cctaccggta tcgcacatac
     6661 gtacatggca gcagaaggaa ttgaaaaagc tgcaaaagca aagaactgtt ttgtaaagat
     6721 cgaaacccgc ggatccggcg gtgcaaagaa tgtgctgaca gatcaggaga ttgctgatgc
     6781 agactgtatt attgtcgcag cagatgccaa ggttcccatg gaacgtttcg atggtaaaaa
     6841 agtgatcgaa tgtcaggtat ccgacggaat cagtaaagca gatcagctca ttgacagagc
     6901 aatcaatggg gatgcaccgg tctaccacgc agcagccggt tcccagacat cttctgccgg
     6961 taacaaatcc ggcggcagtg taggacataa gatctatatg cagctgatga atggcgtatc
     7021 tcatatgctt ccgttggttg taggcggtgg tatcctgatc gccattgcgt tcctgatcga
     7081 tggattaagt gtagatttaa gtgcgcttcc ggcagatcag agagcaaatt tcggtaccat
     7141 tactccggta gcggctctgt ttaaaggaat cggtaataca gcattcggat ttatgcttcc
     7201 gatccttgcc ggatttattg caatggcaat cggtgacaga ccggcacttg cacttggtct
     7261 ggtaggcggt atgatggcag ccaatggtaa atctggtttc cttggagctt tgcttgcagg
     7321 ctttgcagcc ggatatatta ttcttggact tcgtaaatta tgtgataaac ttccggaagc
     7381 cctggaaaag atcgcccctg ttttgatcta tcctgtagtt ggaatcctta ttataggact
     7441 cctgatgaca tttattgtag agccggttat gggcggtatc aacacaggtc tgaataatgc
     7501 cttgacagga atgggaagtt ctagtaaagt aatacttggt attgtgcttg gcggaatgat
     7561 ggctattgat atgggtggtc cgttcaacaa agcagcatat gtattcggaa cagctgcaat
     7621 tgcagcaggt aactatgata ttatggcagc agttatgatc ggcggtatga cacctccctg
     7681 tgcaattgca ctggcaacac tgctatttaa ggataagttc acaaaagaag agagagatgc
     7741 aggtcctacc aactttatca tgggtcttgc atttatcaca gaaggtgcga ttccattcgc
     7801 agcatctgac ccccttcgtg tacttccttc ctgtatcgta ggatctgcgg tggcaggagc
     7861 gatttccatg gcgtttgact gtacattgat ggcaccacac ggtggaattt ttgtattccc
     7921 tgtagttgga aatgcagtta tgtatctggt tgcattggtt gtgggaacag taatctctgc
     7981 agttctgctt ggcctgttaa agaaaaaagc agcataagca gtgaaataaa aaagcaataa
     8041 caaaaaatta aaataaagaa catggaggat atcaaaatga aagaatttaa gtatgtagtt
     8101 acagacaacg aaggaatcca cgcacgtcct gcaggagaac ttgtaaaact ggtaaaggga
     8161 tttgagtcaa caatctctat tgaaaaagaa ggtaaaaaag tagactgcag aaaacttctt
     8221 gcactgatgg gacttggcgt taagaaaggt catgaagtaa cattcacaat tgaaggcgct
     8281 gatgaagaag cagcatatga agcagtgagc aaattcatgc aggacaacct gtaaatttac
     8341 ggaataaaat aagaaactga cagacaggag atgatgcatt catctcctgt ttctgttata
     8401 atgaaatatc agggtcaaaa ggcagaaagt cgttcgtgct tgcacgataa gacttttgaa
     8461 cttgggaccc gccaaacatg aggaagtagc gatttacgaa gtaaatctgc ggattccgaa
     8521 tgtttgtaga attgcgggag ctacgaagca gcggagcaat tcgtagatat cggagaaaat
     8581 aatcagaagt aaacaatcaa agcaaatata caatggaggc aggggtacat gcttacagaa
     8641 cagagatttg atattattct gaagcttctg gaagaaaaaa agagtgttac agtaacagaa
     8701 ctgagagaac ttctggatgc atcagagtcc acagtgcgca gagacattac tgcattggac
     8761 aaagcaggaa aacttaccaa ggttttcggc ggtgcagtag cattaaatca taaagtaact
     8821 gcctatgaac cgacagtagc gcagaaatca gaattaaata aagaagaaaa gcaaaagatc
     8881 gcaaaatatg cagccagcct gatcacaccg gatgattttg tttatctgga cgcaggaacc
     8941 accactggcc tgatgctgga atatctggca ggtgtaagag ctgcctttgt caccaatgca
     9001 gtatcccacg cccagactct ggcaaagatg ggaatccggg tttatttgat cggaggagaa
     9061 ctgaagagtt ccacagaagc agtcgtaggc agtcaggcaa tgcagatgat ccagatgtat
     9121 cattttacaa agggattttt cggaacaaat ggaatcacca gaagagaagg cttcaccaca
     9181 ccggatacca gcgaagcaat tgtaaagagt actgcaatga agcagtgcaa agatgtatat
     9241 attctgacag ataagtcaaa gtttggcgaa gtaagttctg tgacattcgg cgggtttaca
     9301 gatgctaaaa ttcttacaga agaaattccg gaggagtatc aggatagcaa aaatattctg
     9361 aaagtgaaat aaataattga cagtatgccg ccggcagaca gagcaggcag gaatgatatt
     9421 aagattggag agatgtggga tgaagtttgc gcatattggg gatttgcata ttggaaaaag
     9481 ggtgcatgat ttttccatgc tggaggatca gaggtatatt ctggatcaga tgatgaaaat
     9541 ctttgcggaa cagaaagtgg atggagtttt aatcgcaggg gatgtttatg ataagacagt
     9601 gccgtcggca gaggcagtgc agttgtttga tgagtttatt acaggactgg ctaaagctga
     9661 gattcctgtg tacatgatca gtggaaatca tgattcagca gaaaggcttt cctttggggc
     9721 aaagctgttt gaaagcagtg atatttatat ttcgcaggtt tatgatggag agatgaaaag
     9781 gattgtgtta aaagatcagt atggaccaat atctgtatat cttctgcctt ttttgaaacc
     9841 tgcggcagta cgccatgctt tgcagaggga tgacattaat acttatgaag agggtgttat
     9901 ggctgctctg caggagtgtg agatcgatac gacacagaga aatgtgctgg tggcacatca
     9961 gtttgtgacc ggagcagaca gaagtgactc agaagaaaca tgggttggcg gtcttgacaa
    10021 tgtcagtgcg gaagtattta aggattttga ctatgtggca ctgggacaca tccacagacc
    10081 tcagaaaatg gggagagaga ccttgcgtta cagtgggacg ccgcttaagt attctttttc
    10141 ggaagcagat cataaaaagt cggtaacgat tgtggagctt ctggagaagg gaaatgtgag
    10201 ggtcagtaca gtacctttga ttcccagacg ggatatgcgt aagctgaggg gaacctatat
    10261 ggatgtgaca gcgaaggatc attatactgc tgaaaataag atggattatc ttcagattac
    10321 tctgacagat gaggaagatg tgccgggggc actccagaag ctgcgtactg tttatcccaa
    10381 tctgatgcgt ctggaatatg acaataaacg aacacgtgag aaccgggagg ttcaggcagt
    10441 ggaggttcag gaacaaaagt cagaactgga gctgtttgag gagttttatg agctgttaaa
    10501 taatgaacct atgaaagaag agcagacaga gtttgtggaa aaactgatcc aggatctgaa
    10561 ggaggtgcgc gtatga
//
