LOCUS       gnlProkkaHMFIBMKN_2    14212 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HMFIBMKN_2.
ACCESSION   gnlProkkaHMFIBMKN_2
VERSION     gnlProkkaHMFIBMKN_2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 07:01:26
            Original ID  :: gnl|Prokka|HMFIBMKN_2
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14212
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14212
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3371:4212]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3372..4212
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..14212
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14212
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(41..358)
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="MTQPKTDLSYLRSEKAKAEQKLRSCQHREKILERRMSELNRRERV
                     HRLCTRAGMLESFLVCPGELTDNQVMELLKISFRQPEVVLALAKMVHDVHERSNVQNPL
                     E"
     CDS             complement(437..1699)
                     /locus_tag="ctg2_2"
                     /transl_table=11
                     /translation="MYYFIELAGSVTNIALLSLFMSRLFVRNKIQSKWHSVFLTLLCTG
                     QCVLSLFPNWVIPRTLYLLLGGFLLARLFYEVQTWPAAFASGSFFVLGSVVEILAMLLI
                     GVRLPDTDLLMQAGAVRVIYVVFSNLLQIPLLILVSHFFNREESDLRIVWLFPLISIQL
                     ASISVCYVVQCHAADKDFPDYMVFFIAVLLFVNIMIVFYVEALRKNEKEKYLAELTEQH
                     YHLQIEYYQQLLEKQQETKALWHDIKKYTAAMQAVAAQNDSEKLRQIAQAAEDAYERVK
                     DISAVGNPVVDALLNQYLRSAKENQIQVLLDITIPEVLAISTLLLSVVIGNTFDNAIEA
                     CRLINPEKREIHLQLRKQNRILFYSIENPYIDAVTQLRVGKHHGYGLKNVERAVNQNNG
                     NFQLEKVDGNFIVQIRLNCEN"
     CDS             complement(1701..2399)
                     /locus_tag="ctg2_3"
                     /transl_table=11
                     /translation="MAKYTVAVCDDEKEDLSFIVRKITEYDTHQLFEIKTYTDGELLFD
                     ELKSQKISIDLLLLDIEMPSNGFQLARTLQALPKHPMVIFVTRQHEYAVQGYGIAFRYL
                     TKPLNDLLFKSAMDAATQELASRRFLVECDGGTLSLETANIYYIESYGHTILVHSKGKD
                     FQLRMNIQDAAKQLPKRCFTAPHRCYLVNMEHILYTSLDEIMLSNGAKLPISRRKRQEF
                     NQAFNTYLGR"
     CDS             complement(2725..2970)
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MNRRIVQVIGGCDFIATVSVNLVLKMRTDGVVFNRISTVDNGIAI
                     CSSLNRSVWTNRNGSMFAVVQLNRTRFTDGCNIIGL"
     CDS             3372..4028
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_5"
                     /sec_met_domain="AgrB (E-value: 1.3e-36, bitscore: 117.8,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTSCEQTGIRQYKEDARLFLFINENFMLERTISRKVVEWLYGHE
                     IIERSESNIYVYAYELLISSTISIFLILIASCVCGNIWYSLAFLLGFIPLRIYLGGYHA
                     SSHFNCYLAFLSVFLASVVLSYQIVATYGFRLMTTCLLFIIAFLYAPVEAKNKRLPTEK
                     KRKYRHISICLTGFDVILVTTDILPLSRFTTIYYFSKWALIIFAVIPCLTRKFQR"
     CDS             4084..4212
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_6"
                     /sec_met_domain="TIGR04223 (E-value: 8.7e-14, bitscore:
                     43.5, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIYWLSKLTCVVAMGMAVASVNSTCFFTAYQPDVPEDLK"
     CDS             4232..4414
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MDTEYTSPIIEEFDDPTDTFKDNEFVYTYAILAVVGVVAITFGAV
                     LIEMVSLDADGKPVA"
     CDS             4479..5330
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MISINLNNKENLKLTPIFVKNRIPYIRNENNGCITIALPEKRIPQ
                     YKILNKSAVEFSNLMDGTNTVQMILDLLAKKYGENHRTAITADMGIVLSTFLSLKLIIF
                     KKGEFPTMDGITMPLNDKLVVKFAFEHDLKNIVLALDSVKTSDNFTFSSPLAYNAIPDL
                     LQLRSSVFELGKIYFLLLDDTETIRGIAEFETSAISRYITNSVAILSYVSCPSKNLDEF
                     VKGCASLINKVALCRTTKIRTYIPVDQPEAIESFSHSGFEKAAFLKEEYGKIDVCMMDY
                     FV"
     CDS             5341..6399
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_9"
                     /sec_met_domain="PF04055 (E-value: 1.3e-18, bitscore: 60.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.8e-11, bitscore: 36.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVSKTKDSVTGPLHLALDITNKCNYRCLHCYNASGENCVVNNEL
                     TDEEVLELINQISKIKPHTFCFCGGEPLLRKDLIVNCSEILYRNGVSAISAVSNGYYLT
                     EEIADELVQAHVSGIQISLDGFSKNSCFELRQNVDAFSRAVRAIEILSKYKDKISIGVA
                     FCPTKFNTGEFEAVYNFCKANGVRQLRVQPLMIIGRASKHVEEIKPSDEQYVQLIRKIY
                     ELNKSSIQVVSNEKKHVLYKNPICIEWGDPLDHIFRYREGNDSCYTTMSIKANGDIAPS
                     PYLPLSIGNIRCHTLQEYWDSGYSKIWKLPILKKMASTLNTVDDMQCDSMGYNTWIDRD
                     YSCDIVDEHLME"
     CDS             6486..7010
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MIPNNIIRMLFGLFFAIISVAFLLMHKNDIILEEGDRKNNYSISI
                     ICISVILLLFIIVGYIILKELQVIVLSDSQEIFLSEILVFGFMAIFGNCSKKLPFNKYV
                     GLRLPWTLDNCLTWRYAHMLLYELTFPTILLGITFLFALPNKSKTVMIWSILLYIGTPS
                     ILSYFYCRKRH"
     CDS             7015..8679
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 158.8; E-value:
                     3.5e-48)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MHDLNMKTIICFLQKHFLGQTPQILFVTCFSMVVALLSQSSVYIS
                     GKFVDFLTTTQNDMSAYKTLLNYSVLFVILNLTAVLINFAINRMVTILYSNTFYSITRT
                     VSQHIQSISLYKEIKFNSSKITHQLQVDAKEIVSFSLGIFQNFPLNICKLLFSIIMLYF
                     LSKSVLLIIILLVFVYVFFYASLKPKLFKSIKELKTVQSKFFSKLFEQIQFSSYVKRHG
                     LLSSFINRLNLPFKSLYEKMLENQILQFQFSGIDSIILTIGQIMLFILGGYLVLSQKLS
                     VGEFSVINLYFSSIITTIRYFYSVGTSFQNMRVSFNRIYEFLKIPCIENGNETIDSIIN
                     VSIENLKIQFDSKIVISEFHKEFIQGKMYIVAGANGSGKSTLLHTMAGLYDDLYLGSIK
                     YNNIDIRKLDMEMLRHSQIGFVEQDAPLIEGTILYNLYPSKTQEDYSANEILRAKEMVD
                     MFGLHDRILKSCDGLNMRIDEKNHLLSGGERQKIAIIRELLKQPSLLLLDEPTASMDQT
                     SAEILLNELNSIKKDVIVVITTHDERILSYGEEILYL"
     CDS             complement(8765..9046)
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="MKRNQNPDHNHSQKVLSCRYNMDTNRVEARFEDGTTLSIDCIAIE
                     DEYGNTPTQRAELDWLFYNKPLEYAKLVLRGEIEHYLSLGCDHGRLEY"
     CDS             complement(9132..9449)
                     /locus_tag="ctg2_13"
                     /transl_table=11
                     /translation="MKLVLAEKPSVAMSLSKVIGADQRGDGYMEGNGYLVSWCVGHLVE
                     LSQPEAYDEKYAKWKYDDLPILPEHWQYQVSASTKKQFGILKKLMQRKDVESLICATDA
                     G"
     CDS             complement(9790..11508)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 69.6; E-value: 5.2e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_14"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1e-37, bitscore:
                     121.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRREEVVGGGMGAIKATSANGWTRREKVEGADAWARSEQAEGRDI
                     GPGKVSRNIRVSTGGFYGTTRSSFLMEVPMEPKVSIIVPVYNAEKSLARCVDSILNQEF
                     RDFELILMDDGSKDRSGEICDGYARADARVVVVHKENTGVSDTRNQAIARARGTFLQFV
                     DSDDWLTADATKLMVRAAEETGCDMVIADFYRVVGEMVSRKGDIDADQVIGREAFVGFM
                     MENPADYYYGVLWNKLYRRSLVEAHGIRMDAKLSWCEDFLFNLEYVRYATTFYALRTPV
                     YYYVKTKGSLVNQKISFARTVEMKLAMFECYNDFFKHVLDEDAYERKRLQVYHFLVDAA
                     KDGFVFPATIPGTQKLGEERSQALQEVISEDGIIVEKYRDRKLLERYLESVALKYDMTL
                     AELSLLLYRKDAGKALTRGAEAQMPAREDAVEATDRKDAGKSLSRKDLAELMHMSRGDL
                     RAALQKLVSRGMLEVVDVPRKRREAAEIAEATGLFGKRGEAQDADANGMTKKKREPRNI
                     RLELLPASDSVLQDIAAAERDYEQAKFRGFTEDELRQYTALERRVQENEKQILQK"
     CDS             11800..12141
                     /locus_tag="ctg2_15"
                     /transl_table=11
                     /translation="MEYLYKVLGIKATVQRAEFDHLPNYIAVRYRLQKVSMDGQKVIFL
                     YPKTELEQIEDLKAQLKSTGDAILAECAVKDHIWGIGLSMKDPDRLDVKKWHGTNLLGY
                     ALMIVRERV"
     CDS             complement(12452..13615)
                     /locus_tag="ctg2_16"
                     /transl_table=11
                     /translation="MKKMMAMLLASVMAAGTFTTTAFAYTGDDVQKNTPVSTAAQETDA
                     AESTNAGKTDNTDSIEIDPDMQVLPDGYEVSTDADGNLIVTVGGKEYNIGSEKSQKQTG
                     TVVPGITSLHFRSGPGMDQEIIGYLHSGDTVEIVEKCGDWYKVNFNGKTGYAHGKYLNV
                     TDSAKDSSMFSEDALKLFLDLMQSGMSYEDETKSSAALTPEGNMTLVDDIGEEEDKSSQ
                     QFITLVTKAGNTFYLIIDRDKDGNQNVHFLNMVDEADLLALMDEEEAAKYREKEPEVTE
                     PAETEKPQETEPAPEEQKTESEQKKSSPLPMIMLLLFVIGAAGVGGYLYIKMKGVKPAS
                     KKNQPDPDADYHDEDEDTLQLPEDDGDEDEEVDVNEDYEAESEDEPV"
     CDS             complement(13612..13863)
                     /locus_tag="ctg2_17"
                     /transl_table=11
                     /translation="MSLKLEKIAAEREKARRKRDEWEERRKEWDRKYHEQENSEICEMV
                     HAQSLTPEQLAVIIQLAQAAVPNPENLKLDEKETEDME"
ORIGIN
        1 aagaccgcaa tttcaccgga acggtgtata attgcgccct ttattctaaa gggttttgga
       61 cgttgctgcg ttcgtgaacg tcatgcacca tctttgcaag cgccagcacg acttccggct
      121 gacggaacga gattttcaaa agctccatca cctgattgtc ggtcagttct cccggacaga
      181 ccagaaagct ttccagcatt ccggcacgag tgcaaagacg atgtacacgc tctctccggt
      241 tcagctccga catcctgcgc tcaaggattt tctctctatg ctgacaagag cgcagcttct
      301 gctctgcttt ggctttttcg ctgcggaggt aagaaaggtc ggttttcggt tgggtcatgg
      361 catcacactc ctttttcaga aaataaaaag ccaaacaatc agtatggagg ctgatcattt
      421 ggctgtggaa acatatttaa ttctcacagt ttaaacggat ttgcacaata aaatttccat
      481 caactttctc cagctgaaaa ttaccattgt tttgattcac agcgcgttct acgtttttca
      541 gcccgtaacc atggtgcttc cctacgcgca actgggtgac agcatctata tatggatttt
      601 cgatactgta aaacaggatt cggttctgtt ttcgtagttg caagtgaatc tctcttttct
      661 ctggattgat aagtcggcaa gcctcaattg cattatcgaa tgtattacca ataacaacgc
      721 ttaacaacaa tgttgagata gcaagaactt ctggaattgt tatatccaaa agaacttgga
      781 tctggttttc ttttgcagaa cggagatatt gatttagtaa agcatcgact acaggattac
      841 caacagcaga gatgtctttc acacgttcat aagcatcctc agctgcttga gcaatctgac
      901 ggagtttttc agagtcattt tgcgctgcaa ccgcttgcat tgcggcggta tattttttaa
      961 tgtcatgcca aagagccttt gtttcctgct gcttttccag aagttgctga tagtactcta
     1021 tttgtaaatg atagtgctgt tctgttagtt ctgccaaata cttttctttt tcatttttcc
     1081 gcagggcttc cacatagaaa acgatcataa tattcacaaa aagcaggacg gctatgaaga
     1141 aaaccatata gtccggaaag tctttatctg ctgcatggca ctgtacaaca tagcacacgg
     1201 agatacttgc aagttgaata ctgattagag gaaaaagcca tacaatccgt aaatcacttt
     1261 cttcgcggtt gaaaaaatgc gacactaaaa taagaagtgg tatttgaagc agattagaga
     1321 acacaacata aatcactcgc actgctccgg cctgcattaa aagatctgta tctggcagac
     1381 gaacgccaat caataacatc gcaagaatct ctaccacgga acccaagaca aaaaatgaac
     1441 cgcttgcgaa agccgctggc caagtctgaa cttcatagaa cagccttgct agtaaaaaac
     1501 ctccaagcag taagtaaagc gtcctcggta tcacccaatt cggaaaaaga cttagaacgc
     1561 actgccctgt acatagtaaa gtaagaaaga cagagtgcca tttgctttga atcttgtttc
     1621 gcacaaacaa tcgactcata aacagactga gcagtgcaat gtttgtaaca cttccggcca
     1681 attctataaa ataatacatt ttaccgtcct aaatatgtgt taaacgcttg attgaattcc
     1741 tgacgttttc ttcggctaat aggcagcttt gccccgttgg aaagcataat ttcgtccaat
     1801 gaagtataaa ggatgtgttc catattaaca agatagcacc tatggggtgc tgtaaagcag
     1861 cgtttaggaa gctgcttggc tgcatcttga atattcatcc gaagctgaaa gtctttacct
     1921 ttgctgtgaa ctaaaattgt atgaccataa ctttcaatat agtaaatatt tgcagtttcc
     1981 agcgataatg ttccaccatc acattcaaca aggaatcggc gtgatgcaag ttcttgagtt
     2041 gccgcatcca ttgcggattt aaacaatagg tcgtttaatg gctttgtcaa atagcgaaaa
     2101 gctattccat aaccttggac ggcatactca tgttgtctag tcacaaaaat caccattgga
     2161 tgttttggca aagcttgtag agttcgtgca agttgaaatc cattggatgg catctctatg
     2221 tccaaaagca agagatcaat ggatattttt tgtgatttta attcgtcaaa aagtagttct
     2281 ccatctgtat aggttttgat ctcaaagagc tggtgtgtgt catattctgt gatttttctt
     2341 acgatgaaac ttaagtcttc tttttcatca tcgcagaccg cgactgtata ttttgccatc
     2401 tgaagatcct ccaattagat ttggtgttta caaccattat aaatggtagg ataggaatca
     2461 gcaagtctcc aaattgaccg ttcgtgccag aaagctaacc attcacgaca aatagattac
     2521 ttttgtttga aattatggta tcatcaacta aaaatcatga tgtatagcgt tagctatatg
     2581 tctatgattt gtaaatttca ttttaggagg tcgatcacca tgaaaaagct ttctcggcgt
     2641 agcttccttg cactatccgg tagtgctgcc cttttgatgg cagtaaatcc tttaatggca
     2701 aacgccgcaa tcactgagcc ggaactaaag tcctattatg ttgcacccat cggtgaatct
     2761 ggtacgattc agttggacaa cagcgaacat ggaaccatta cgattcgtcc agacactccg
     2821 attcagggac gagcaaatgg cgatcccgtt atccacggta cttatacggt tgaatacaac
     2881 tccatcggtt cgcattttga gtacaaggtt gacactaaca gtagctataa aatcacagcc
     2941 gcctatgact tggactatac gacggttcat gagattctct ctcatagtct tacacacaca
     3001 tcgactatgg cgagcctgaa aattgaattc aaatatttca gcgttgcagg aactgctaat
     3061 gcatacctta attttgtaat ccgaaacgga aaaatctatg ttgaaacaaa catgtgattt
     3121 caacatacgc taccgggaga tataataatg gaaaaatcaa ctggaattct gttactaata
     3181 gccgtagcgt ttcgattgtt ggttcttttt ttcttttcgc aaagcatctt tttaacccag
     3241 ctttccattt ctacttttat cgtggtgatg atcattgcca ttatactgtt gataaggaaa
     3301 tggcttcatt ggcgaaactc gaaataaaat caattactgc tatctactcg cttagttaaa
     3361 aagtttcatt cttgttaact tcttgtgaac agacgggcat ccgacaatac aaggaggatg
     3421 cccgtctgtt tctttttata aatgaaaatt ttatgttaga gcgtactatc tctcgaaaag
     3481 tcgtcgaatg gctatatggt catgaaatta ttgaacgcag tgaatcaaat atttatgtat
     3541 atgcctatga attgttgatt tcatcaacaa taagtatttt cctcattctt atcgcatcat
     3601 gtgtttgcgg taatatatgg tactcattgg cttttctcct cggcttcatc ccacttcgaa
     3661 tatacctagg aggatatcat gcatcctcac attttaactg ctacttggct ttcttatctg
     3721 tctttcttgc aagtgtcgtt ttaagttatc aaattgtggc gacatatgga tttcggttga
     3781 tgacgacttg tttactattc ataattgcat ttttgtatgc ccctgttgaa gccaaaaaca
     3841 agagacttcc cacagaaaag aagcgaaagt ataggcatat tagcatctgt ttgactggtt
     3901 ttgatgtcat ccttgtgaca actgatattc taccactctc aagatttaca acaatttact
     3961 atttttcgaa gtgggcattg attatatttg cagtcattcc ttgcctgaca cgaaaatttc
     4021 aaagatgaac tcggttttcc ttttgggtga ccgttttcaa aaatcaaaag aaaggagaaa
     4081 aaaatgaaaa aaataatata ttggctgagt aagctcactt gcgttgttgc aatgggcatg
     4141 gcagtagcaa gtgtaaatag cacctgcttc ttcaccgcat atcagccgga cgttcccgaa
     4201 gatctaaaat aaaatgaagg agagaaatat tatggatact gagtacactt ctccgataat
     4261 cgaagaattc gatgatccca ctgatacttt taaagacaat gaatttgtct atacctatgc
     4321 tatcctcgca gtcgtaggag tagtcgcaat aacctttggg gcagttttga tagagatggt
     4381 ttcgcttgat gcagatggta agcccgtagc ataatagagg agaaaccgtc agccgttgtg
     4441 agtggtctcg tcaaggctga cggtttttag gtgaaaatat gatctcgatt aatttgaata
     4501 ataaggaaaa tttgaaactg acacctatat tcgtgaagaa tcgtattcca tatataagaa
     4561 acgaaaataa tggttgcatt actatagcac ttccggaaaa gcgtatccca caatataaaa
     4621 tcttaaataa aagtgctgtt gaattttcca atcttatgga tgggaccaat acggtacaaa
     4681 tgattttaga cttactcgca aaaaaatacg gcgaaaatca tcgcaccgct ataacagccg
     4741 atatgggcat agtgctttcg acttttttaa gtttgaaact tattattttt aaaaaaggag
     4801 aatttccaac tatggatggg ataacaatgc ctctcaatga taaactggtc gtcaagtttg
     4861 catttgagca cgatttaaaa aatatcgtgc ttgctcttga ttcagttaaa acatcggata
     4921 atttcacgtt ttctagtccc cttgcatata atgctattcc agatcttcta caattaagat
     4981 cttctgtatt tgaactcgga aaaatttatt ttttactctt ggatgacacg gaaactatcc
     5041 gtggaattgc agaatttgaa acatctgcga tatccagata tataactaat agtgttgcga
     5101 ttctgtcata tgtgagctgc ccatctaaaa atctggatga atttgtaaaa ggctgtgcat
     5161 ctcttattaa caaagtagct ctttgccgta caacaaaaat tcgaacatat atcccagtag
     5221 atcaacctga agcaatagaa agcttctcgc attccggatt tgaaaaagct gcatttttaa
     5281 aagaagagta tggaaaaatt gatgtttgta tgatggatta tttcgtgtga ggataagtat
     5341 atgggagttt caaaaacaaa agactcggtg acgggtccac tgcatttggc tttggatata
     5401 accaacaaat gcaattatcg ttgtctgcat tgctataatg ccagcggtga aaattgtgtt
     5461 gttaataatg aattgacgga tgaagaagtc ctagaactta ttaatcaaat ttcaaaaatc
     5521 aagccgcaca ctttttgctt ctgtggagga gaaccgcttt tgcgcaaaga tttaattgta
     5581 aattgctctg agattctcta cagaaatggg gtttccgcaa tatcagctgt atcaaatggt
     5641 tactatttaa ccgaggaaat agcagatgag ttagtacagg ctcatgtatc tggaattcaa
     5701 ataagccttg atgggttttc aaaaaatagt tgttttgaat taagacaaaa tgttgatgca
     5761 tttagtcgag cggttagggc aatcgaaatt ctatcaaaat ataaggacaa gatttcaatc
     5821 ggtgtggctt tttgccccac aaaattcaat actggagagt ttgaagccgt ttataatttt
     5881 tgtaaagcta atggtgtacg tcaattgcga gtccaaccat tgatgattat cggtcgtgca
     5941 agcaagcatg tggaagaaat caaaccctcg gatgaacaat atgtacaatt aataaggaaa
     6001 atctatgaac tgaacaaaag ttctattcaa gtcgtttcca acgaaaagaa acatgttcta
     6061 tataaaaatc ctatttgtat tgaatggggt gatccactag atcatatttt caggtatcgt
     6121 gaagggaatg atagttgtta tactacaatg tcgattaaag caaatggaga tattgctcct
     6181 tcaccatatt tgccactttc gattggaaat attcgttgtc atacacttca agaatattgg
     6241 gactccggct attccaaaat ttggaagctc cccattttga agaaaatggc cagtacatta
     6301 aacaccgtag atgatatgca atgtgattca atgggctata acacctggat cgatagggac
     6361 tattcttgcg atattgttga tgaacatctt atggaatgat tttaggtttg aggtgagaaa
     6421 agatgaaaca cgacaaactg ttccttgtaa gaattttgtg tttgatcgga attgcaggag
     6481 aattattgat tcccaataat atcattcgta tgttatttgg tctgtttttt gcaataataa
     6541 gtgttgcttt tttgttgatg cacaagaatg atataatttt ggaagaaggt gacagaaaaa
     6601 acaattattc aatttctata atatgtatta gcgttattct acttttattt attatcgttg
     6661 gttatataat attaaaagag ttgcaagtca ttgtgctatc tgattcgcag gaaatttttc
     6721 tttcagagat tctcgtgttt ggctttatgg ctatctttgg aaattgctct aaaaagcttc
     6781 cattcaataa gtatgttggt ttgcgtttac catggacatt agacaattgt ctaacatgga
     6841 gatatgcaca catgctttta tatgaattaa cttttcctac tatactttta ggtattacat
     6901 ttctttttgc tctgcccaat aaatcgaaaa cggtcatgat ttggtcaata ctattgtata
     6961 ttggcactcc gtccatcctt tcttattttt actgcagaaa aaggcattaa taagatgcac
     7021 gatttaaata tgaaaaccat aatatgcttt ttgcagaaac attttttggg acaaacaccc
     7081 caaattcttt ttgtgacttg tttttcgatg gttgtcgctt tactttccca aagttctgtg
     7141 tatatttctg gaaaatttgt ggattttttg acaaccactc aaaatgacat gtcagcatat
     7201 aaaacgcttc taaactatag tgttcttttt gtgattttga atttaacagc tgtgttaata
     7261 aactttgcga ttaaccggat ggttactatt ctttattcaa acacttttta ctcaatcaca
     7321 agaactgttt cacagcatat acaaagcatc tctttgtaca aagaaataaa attcaactct
     7381 tcaaaaatca cacatcagct tcaggttgat gccaaagaga tcgtttcctt ttcgctgggg
     7441 atttttcaga attttccact aaatatatgt aaacttcttt tttccattat aatgctatat
     7501 tttttgagca aaagtgtatt gctgattatt atcctcttgg ttttcgtgta tgtctttttt
     7561 tatgcatcat taaaaccaaa actctttaag tcaatcaaag agttaaaaac cgttcagtca
     7621 aaattttttt ccaagctgtt tgaacagatt cagttttcat cttatgtaaa aagacacggc
     7681 cttttaagtt cttttattaa tcgactcaat cttccgttta agagcctata tgaaaaaatg
     7741 ttagagaatc aaattcttca atttcaattt tcaggaattg attcaattat tctaacgatt
     7801 ggacaaataa tgctctttat attgggtggc tatttggttc tcagtcaaaa attatcggtc
     7861 ggagaatttt cagtcattaa tctttatttt tcatctatca ttacaactat tcgatatttt
     7921 tattcggtcg gcacatcttt tcagaatatg cgagtttcat ttaatcgaat ttatgaattc
     7981 ttaaaaattc catgtattga aaatggaaat gaaaccatcg atagcattat taacgtgtca
     8041 attgagaatt tgaaaatcca gtttgactcc aaaattgtca taagcgaatt tcataaagaa
     8101 tttatccaag ggaaaatgta tatcgttgca ggagcaaatg gtagtggaaa atcaaccctg
     8161 ttacatacaa tggctggact atatgatgac ctatatctgg gaagtatcaa atacaataat
     8221 attgatataa gaaaactgga tatggagatg ttgcgtcact cccaaattgg ttttgtcgaa
     8281 caggacgcgc cacttattga aggcacaatt ttgtataatc tttacccatc aaaaacgcaa
     8341 gaagattatt cggctaatga aattcttcgt gcaaaagaaa tggttgacat gtttggtctc
     8401 cacgatcgta tcttaaaatc atgtgatgga ctaaacatga gaatagacga gaagaatcat
     8461 ctgctttcag gaggagaaag gcaaaagata gcaataatcc gcgaattact gaaacagcca
     8521 tcgttacttt tgttggatga accaacggcg tctatggatc aaacaagtgc tgaaatttta
     8581 cttaatgaat tgaattctat caaaaaggac gttattgtcg ttattacaac acatgacgag
     8641 agaatactat cctatggaga agaaatttta tatctataac tcataagaag ctgagcttta
     8701 taatagccct ctatttgcaa cggctgcaaa tagagggcta ttgttttgct ttggatatta
     8761 agggttagta ctccagtcta ccatggtcgc aaccaagcga gagataatgt tcaatttcac
     8821 cccgcagcac aagcttggca tactccaaag gcttattata aaatagccaa tccagctctg
     8881 ctcgctgcgt aggggtgttg ccgtattcgt cctcaatggc gatgcagtcg atcgaaagag
     8941 tagttccatc ttcaaatcgg gcttccaccc ggttggtgtc catgttgtag cggcaggaaa
     9001 gcactttttg agagtgatta tggtcaggat tctgatttcg tttcatttga atggctcctt
     9061 taataatttt ggaatttgat tttcaacgag atgaggtctc ttttttcttt ctcttaagtc
     9121 acctaaccac actatcctgc atcggttgca cagatcagac tctccacatc tttccgctgc
     9181 atgagctttt tcaggattcc gaactgcttt ttcgtgctgg cggacacctg atactgccaa
     9241 tgttccggca aaatcggaag atcatcatac ttccactttg catacttttc atcataggct
     9301 tccggctggg aaagttccac cagatgcccc acacaccaac tgacaaggta gccattgccc
     9361 tccatataac cgtccccgcg ctgatctgcc ccgatcactt tcgagagact catggcaacc
     9421 gagggctttt ccgctaatac aagcttcatt cgatactgct cctttcgcaa aaaaattagc
     9481 agccaggcac cgaagcgcat gactgctatg taaggaacgg tattctgttt taggtctaca
     9541 aactggggct tttatgatct tgccacagct tatcagtcta tgcacgtcaa ctgttgaaac
     9601 cgccgtgtac cgaacggtac gcacggtggt gtgagaggac ggcggctagt caccgcctcc
     9661 tactcgcttg tgcccatgtt tcggccctcc acatcatcac tccgcgcatg cgttgtgcct
     9721 cgccgcaacg cattctgccc ctcgctgact catcgccagg catcgctgat ggtgttcgtc
     9781 tgcccatcct cacttctgca gtatctgctt ttcgttctcc tgcacacgcc gctcgagcgc
     9841 tgtatactgc cggagctcgt cctcggtaaa tccccggaac ttcgcctgct cgtagtcacg
     9901 ctccgcggcc gcgatatcct gcagcaccga atccgacgcc ggcagcagct cgagacgaat
     9961 attccgcggc tcgcgttttt tcttcgtcat tccgttcgcg tctgcatcct gtgcctcgcc
    10021 acgctttccg aaaagaccgg tcgcctcggc tatttccgcc gcttcacgtc gtttcctcgg
    10081 cacgtcgacc acttcgagca tcccgcgtga gaccagcttc tgcagcgcgg cgcgcagatc
    10141 cccgcggctc atatgcatca gctccgcgag atccttccgg ctcagcgact ttccggcatc
    10201 ctttcgatca gtcgcctcca cggcatcttc ccgcgcaggc atctgcgctt cagcccctcg
    10261 agtgagcgcc tttcccgcgt ccttccgata cagcagcagc gacagctccg ccagcgtcat
    10321 atcatacttc agcgccaccg actcgagata gcgctcgagc agcttccggt cgcggtactt
    10381 ctccacgatg atcccatcct ccgaaatcac ctcctgcagc gcctggctcc gctcctcacc
    10441 gagcttctgc gtccccggaa tcgtcgccgg gaacacgaaa ccatccttcg ccgcatccac
    10501 tagaaaatga tagacctgca gccgcttccg ctcatacgca tcctcatcca gcacatgctt
    10561 gaagaagtcg ttgtagcact cgaacatcgc gagtttcatc tccaccgtcc gcgcgaagct
    10621 gatcttctga ttcaccagcg aacccttcgt cttcacataa tagtagaccg gcgtccgcag
    10681 cgcatagaac gtcgtcgcat agcgcacata ctcgagatta aacagaaaat cctcgcacca
    10741 gctgagcttc gcatccatcc ggatcccgtg cgcctccaca agcgagcgcc ggtacagctt
    10801 attccacagc accccatagt agtagtccgc cgggttctcc atcatgaagc caacgaacgc
    10861 ttcacgcccg atcacctggt ccgcgtcgat atcccccttc cgcgacacca tctctccgac
    10921 gacacgatag aaatccgcga tcaccatgtc gcagcccgtc tcctcggccg cccgcaccat
    10981 cagcttcgtc gcatccgccg tcagccagtc atcactgtcc acgaactgca gaaacgtacc
    11041 ccgcgcccgc gcgatcgcct ggtttcgcgt atccgacacc cccgtattct ccttatgcac
    11101 gaccaccacg cgcgcatccg cccgcgcata tccgtcgcag atctccccgg accgatcctt
    11161 acttccatca tccatgagga tcagctcgaa atcccgaaac tcctgattca gaatactgtc
    11221 cacacagcgc gcgagactct tctccgcgtt atacaccggc acgatgatac tgaccttcgg
    11281 ctccataggc acctccatca aaaaactact tctagttgta ccataaaacc ctcccgttga
    11341 cactcgtata tttctgctca cttttcccgg gccaatgtct cggccctccg cctgctcact
    11401 ccgcgcccac gcgtccgcac cctccacctt ctcacgtcgc gtccacccat tcgcactcgt
    11461 tgcctttatc gcgcccatgc ctccgcccac cacctcctca cgtcgcatcg aagcaccaat
    11521 tccctcatga aaatgtcata ttacagcata aattcgctca tgaaagtgta atgaagcacg
    11581 gattattccc tcatgaaagt ggcaaaatac tgaaaagaac gctcataaaa gtggcagagc
    11641 acggaaatct gagaggaaaa agaaggtgcc atggtgttaa attattctta tgatatttcc
    11701 gcttcctgat gatttttttg aattatctta actttaatat cgaaacttaa cttaaaacaa
    11761 gttataatac aaaaatagag ttaaatagaa ggagaacata tggaatatct ctataaagtt
    11821 ctgggaatta aagcgacagt tcagcgcgca gagtttgacc atctgcccaa ttatatagct
    11881 gtaaggtatc gtttacagaa ggtatccatg gatggacaga aagtgatttt tctttatcca
    11941 aagacagagt tggagcagat cgaagacctg aaggctcagc tcaaatccac cggcgacgcc
    12001 atcctcgcag agtgcgccgt caaggaccac atctggggca tcggcttatc gatgaaggac
    12061 ccagatcgac tcgacgtgaa aaagtggcac ggaacgaacc tgctggggta tgcactcatg
    12121 atcgtacgag aacgggtgtg aagggcgaaa atccagatac caatataaat acgtatttga
    12181 tgatttatag atatgaataa atgcagatca aaatgcgcag aatatgagca cttatagaca
    12241 tttaatcaac actatatgaa aatatgccta ttatttttga gagatgctgg atggtaaaat
    12301 tccgagttgt tgagctgttc ttactttcta ttttatcaga tatcgcctac agagtccata
    12361 gcttcatagc tcaaaacagt tcacccacca accatttggc tatgtaaagg ggacggcttt
    12421 tcagccgccc caccggtcaa cgctgcgtta atcagacagg ttcatcttcc gattccgctt
    12481 cataatcctc gttgacatcc acttcttcgt cctcgtcacc atcatcctcc ggcagctgga
    12541 gcgtatcttc atcctcatcg tgataatccg catccgggtc cggctgattt ttcttggacg
    12601 caggctttac gcccttcatc ttgatataga gataaccgcc gacaccggct gcaccgatca
    12661 caaacagaag cagcataatc atcggaagcg gagacgattt cttctgctcg ctctctgttt
    12721 tctgctcttc cggtgccggt tccgtctcct gcggcttttc ggtttccgca ggttccgtga
    12781 cttccggctc cttctcccga tacttggcag cttcctcttc atccatcagc gcaagcagat
    12841 cggcctcgtc caccatgttc aggaaatgca cattctggtt gccgtcttta tcgcggtcga
    12901 tgatcagata aaaggtgttg cccgcctttg tcaccagcgt aatgaactgc tggctggatt
    12961 tatcttcttc ctcaccgata tcgtccacca gcgtcatatt tccttccgga gtcaaagctg
    13021 cactggattt cgtctcatcc tcgtatgaca ttccactctg catcagatcc agaaacagct
    13081 tcagcgcatc ttcactgaac atgctgctgt cttttgcaga atccgtgaca ttcaggtact
    13141 ttccatgtgc atacccggtt ttgccgttga agtttacctt ataccagtca ccgcattttt
    13201 cgacaatctc caccgtatcg ccggaatgca gatatccgat aatctcctga tccatgccgg
    13261 gaccggaacg aaaatgcaga ctggtgatcc ccggcaccac cgtaccagtc tgcttttggg
    13321 acttttcgct gccgatattg tattctttgc cgcccaccgt aacgatcagg ttcccatccg
    13381 catccgtaga gacctcatag ccatccggca gaacctgcat gtccgggtcg atttcgatgc
    13441 tgtcggtatt gtccgttttc cccgcatttg tgctttctgc tgcatccgtc tcctgtgcag
    13501 cggtactgac aggcgtgttc ttctgcacat catcgcccgt ataggcaaat gcagtggtcg
    13561 taaaggttcc tgccgccatc acgctggcaa gcagcattgc catcatcttt ttcattccat
    13621 atcctccgtt tctttctcat ccagtttcag gttctccggg ttgggaaccg cagcctgcgc
    13681 cagctgaatg atgactgcca gctgttccgg ggtcaggctc tgggcatgta ccatttcaca
    13741 gatttcgctg ttttcctgct cgtggtactt tctgtcccat tcctttctgc gctcctccca
    13801 ttcatcgcgt ttcctgcggg ctttctcgcg ctccgcagca atcttttcca gtttcaagct
    13861 catatcgtat cctttccggg cgaataaacg ccctattttt atcgaattct tcccatgcag
    13921 tagtagtgct gccgccagta gctcgtctca atggaagcat aggaaattgg tgagccacag
    13981 tggatcatca tcccgttgcc gacataaatg cccacatggg atgcgccact ggtgttgtag
    14041 gttttctgga agaagatcag gtctccgggc tttgcctcac tcttcgggat aatgtcgcat
    14101 tttcccatca gaccgttggc cgtctgcctg cctacattcc agccattgcc gcagtggttg
    14161 atgacccagc ttacaaaacc ggagcagtca aaactggtac tcggcgagct gc
//
