LOCUS       c00022_gnlPro..        29921 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LLILHNAC_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:04:30
            Original ID  :: gnl|Prokka|LLILHNAC_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 6866
            Orig. end    :: 36787
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     cand_cluster    1..29921
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="neighbouring"
                     /product="Rnf_complex"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..29921
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     protocluster    1..25071
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[16866:21937]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15071
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..25071
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     CDS             complement(1114..1554)
                     /locus_tag="ctg22_9"
                     /transl_table=11
                     /translation="MAEKTSAEVIIGGKVYTLSGYEGEEYLQKVATYINNKLGEFQGME
                     ELRHLSGDMKATLLQLNIADDYFKAKTQVEKLEREIEQKEKEIYDLKHDLISNQIKAES
                     DEKARKELEEQNKELLINKAKLEASLEDALLGKVTEKDKTEE"
     CDS             complement(1633..2631)
                     /locus_tag="ctg22_10"
                     /transl_table=11
                     /translation="MEKRVISTQVQEEDLKIEKSLRPQTLDDYIGQQKAKENLKIYIEA
                     AKARGESLDHVLFYGPPGLGKTTLAGIIANEMGTHMKVTSGPAIGKPGEMAAILSNLQE
                     GDVLFVDEIHRLNRQVEEVLYPAMEDYAIDIMLGKGATARSIRLDLPKFTLVGATTRAG
                     LLSAPLRDRFGVVHHLEFYTVEELKTIILHSALTLGVEIDEEGAYEMARRSRGTPRLAN
                     RLLKRVRDFAQVKYDGRISKEVASFALDLLEVDKMGLDQNDRNILMTMIGKFAGGPVGL
                     DTLAAAIGEDAGTIEDVYEPYLVKNGLINRTPKGRVVTELAYQHLGIEHSV"
     CDS             complement(2671..3282)
                     /locus_tag="ctg22_11"
                     /transl_table=11
                     /translation="VYAYIKGVLADVEEESVVVEAGGIGYRIYTTGQTFDYLPAVGEEV
                     KLYTYLNVREDAMILYGFLTKDDLRVFKLLIGVNGIGPKGALAVLSVMTTDDLRFAVLG
                     DDAKAIAKAPGIGAKTAQRVILELKDKLSLEEAFELKSEHVSRQNENGSSGVKNEAVQA
                     LVALGYASSEALKALNGIEITDDMDVETLLKAALKNMAFL"
     CDS             complement(3296..3814)
                     /locus_tag="ctg22_12"
                     /transl_table=11
                     /translation="VKKTDSTPLRDKVAYLGVFLALALICSYVESLIPFYFGIPGVKLG
                     LTNIVVVLMLYCVGTKEAFAISMLRIVLAGFLFGNLFSILYSLAGGMFSFLVMYLLKRT
                     GKLGVLPVSVAGGMSHNIGQIAVAAFVVENINIFYYLPVLFVAGIVTGLLIGVAAQEII
                     LRIGGRLKR"
     CDS             complement(3780..4166)
                     /locus_tag="ctg22_13"
                     /transl_table=11
                     /translation="MKKRISRNDVIFLAILLAVVTVFLVIYERTGMRADAGACVRVTVD
                     GSVYGTYALGEEQEIPIVQDGVTTNVLTIRDGRADMTEADCPDKLCVHQKAISKNHEMI
                     VCLPNKVVVEVTGSEENGFDSIAR"
     CDS             complement(4163..5626)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_14"
                     /sec_met_domain="Radical_SAM (E-value: 3.2e-36, bitscore:
                     116.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKIDIEIIDKKQIPQSEPERQYYFMDIAKNYVEQLSAKKGSPL
                     TFHVTTFGCQMNARDSEKLVGILERIGYVETDTEDADFVIYNTCTVRENANNKVYGRLG
                     VLQNYKKKNPHMLIGLCGCMMQETVVVEKLKESYRFVDLIFGTHNIYKFAELIVTAMES
                     DSMTIDIWKDTDQIVEDLPVERKYSFKSGVNIMFGCNNFCSYCIVPYVRGRERSREPKE
                     IIREIEQLVADGVVEVMLLGQNVNSYGKNLKEPVTFAQLLEEVEKIEGLERIRFMTSHP
                     KDLSDELIEVMGRSKKICKHLHLPLQSGSSRILKIMNRRYDKEHYLELVDKIRAAVPDI
                     ALTTDIIVGFPGETEEDFEETMDVVRKVRYDSAFTFIYSKRTGTPAASMEEQVPEDVIK
                     ARFDRLLKEVQKISAEKAEALTGQTLPVLIEEQNEQDASLVTGRLSNNSVVHLPGTADM
                     IGKILDVKLTECRGFYYLGERADGNGQTV"
     CDS             complement(5642..6925)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_15"
                     /sec_met_domain="Aldedh (E-value: 2.3e-23, bitscore: 73.7,
                     seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTELCKSAKEVSRQIGNLDTNTKNEVLRAAAEAIVAHTEEIIR
                     ENEKDLARGRENHMPEGLLDRLMLNPSRMEQMAEGLRQVADLADPIGEVLSMKKRPNGL
                     MIGKKRVPLGVVGMIYEARPNVTVDAFALCFKTGNAVILKGGSDAILSNIVIVSVLQEV
                     LEAHGIPRAAVSLIEDTSRETAAAFMKMNEYVDVLIPRGGAGLIRAVVNQATIPVIETG
                     TGNCHIYVDESADFDMAIRIILNAKTQRIGVCNACESLVIHEKIVDAFMPKLAAALQQK
                     DVVIHADEKSLAAAERREAANGGDLKKELLSAATEEDWGREYLDYMISVKTVSSLDEAI
                     AHINRYNTGHSEAIITENYTNAQRFLDEIDAACVYVNASTRFSDGFEFGFGAEIGISTQ
                     KLHARGPMGLDALTSTKYIIYGNGQTRP"
     CDS             complement(6945..7589)
                     /locus_tag="ctg22_16"
                     /transl_table=11
                     /translation="MEKRQDFPDAALTQEKARQQIRARHKAWRLELPQEEVQEKSRKIC
                     ERLAASDWYHNSAVIYGYYPLGAEADCLPFLAQALSDGKTVALPVTSKERLQRDCGQVK
                     RMQDTHRMEFYRIRELSRVREGAFHVMEPDESCKRIGEEDAVVLVPGLVFDRKGNRYGY
                     GGGYYDRYFARFPKLSRMAVAFEGQIEEQLAALPTDVRMHRIYTEEREYRI"
     CDS             complement(7564..7788)
                     /locus_tag="ctg22_17"
                     /transl_table=11
                     /translation="MNQEQIDRINALYRKSKAEGLTEEEKKEQALLRKQYVADVKKNLA
                     AQLNNIDMVNPDGSVENLGDKYGKKTGLS"
     CDS             complement(7810..8511)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_18"
                     /sec_met_domain="AA_kinase (E-value: 2.4e-34, bitscore:
                     110.3, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVCLVSSGAIAVGRQTLGMDERPKDISTKQACAAVGQARLMMIY
                     QRLFAEYNQVAGQVLMTKNTMVNPVSRENAKNTFDELFRLGAIPIVNENDTVSTYEMQF
                     GDNDTLSAIVASLIGADLLILLSDIDGLFTDDPHKNPDAKLIEVVEEMDASIYGMAKSS
                     TGSDVGTGGMATKLTAAKIATLSGTDMIIANGRDVCILHHIFDDSFKGTIFQAKKKESF
                     RIEDFILETIG"
     CDS             8840..9880
                     /locus_tag="ctg22_19"
                     /transl_table=11
                     /translation="MMRKKKVLSCLLVPLLSANLLLSGCSRTADEPVTKSGFYFNTVIS
                     VSIYEKGSEELLDDCFALAQKYEGYFSNTIPDSDISKINDAGGAPVTVHDETIELLKTG
                     IAYGDLSGGKFDITIGRLSDLWDISTKALLDQTDASMIPSDADIQTALATVDYREIQID
                     GNTVTLQNPDARIDLGGIAKGYIADQMKAYLNQKGITSGYINLGGNVLALGAKTDGSAY
                     TIGIQRPFGEENEAIASVSITDQTVVSSGVYERYFEVDGTRYHHILDTATGYPYDNGLL
                     EVTIITGASVDGDGLSTTCFSLGLEDGMALVESLDATEAIFITDDYEVHTSSGMGTVIP
                     YEILED"
     CDS             complement(10001..10792)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4_9"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:4Fe-4S dicluster domain (Score: 32.3; E-value:
                     2.8e-10)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_20"
                     /sec_met_domain="Fer4_7 (E-value: 6e-09, bitscore: 27.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_9 (E-value: 1.8e-10, bitscore: 32.3,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.4e-08, bitscore: 24.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2.7e-16, bitscore: 50.4,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.7e-05, bitscore: 16.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVTAILFAALIVGGVGILIGFFLGISGEKFKVEVDEKEEAILGV
                     LPGNNCGGCGYAGCSGLAAAIAKGEAPVNQCPVGGAPVAAKIGEIMGVAAEEGERKVAF
                     VKCAGTCEKAGRDYEYTGNEDCAAMAFVPNGGPKSCNYGCLGYGSCVKACPFDAIHIVD
                     GIAQVDKEVCKACGKCVAACPKHLIELVPYKAKHIVQCSSKDKGKDVMKACSVGCIGCH
                     LCEKNCPKDAVHVIDNVAYIDQEKCVGCGICAQKCPKKIIL"
     CDS             complement(10806..11402)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_21"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.7e-65, bitscore:
                     210.5, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLLLIAIGSAIVNNVVLSQFLGICPFLGVSKKTETAAGMGGAV
                     VFVITISSFVTALIYKYILANSYLMSKGIDLTYLQTIVFILVIAALVQFVEMFLKKSMP
                     ALYQSLGVYLPLITTNCAVLGVALTNVTKEYGILESVVNGFATAFGFLIAIVLMAGVRE
                     KIEYNDIPKPFQGTAIVLISACLMSIAFMGFSGMI"
     CDS             complement(11417..12139)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_22"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.7e-69, bitscore:
                     224.7, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKNVERLYNGLIKENPTFVLMLGMCPTLAVTSSAINGLGMGLST
                     TVVLVLSNMLISAFRKVIPDGVRMPAYIVIVASLVTVVQFIMQAYTPSLSESLGVYIPL
                     IVVNCIILGRAESYASKNPVVPSLFDGLGMGLGFTMGLTLIGLFRELLGAGQIFGFQIL
                     SLSWFTPITIFVMAPGAFLVLACLVAVMKIVREKMAAKGKPLAEPSGCITGDCAGCGMS
                     AACTGKKPAAEAPAEKAE"
     CDS             complement(12143..12751)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_23"
                     /sec_met_domain="FMN_bind (E-value: 3.1e-20, bitscore:
                     64.0, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIVHDALVLFAFTVVLGLILGVVYGITKGPIDQVNYEKTQSA
                     YKQVFEDADSFEEYADFDTAAAEDLMAQNGYSDDIEAVNTALDASGNPLGYVLTVTAKD
                     GSQGSITFSVGIQNDGTVNGYSITSISETPGLGMKAQEEPFYSQFEGKNVDSFTVVKST
                     PSADNEIEAISGSTITSKAMANGVNACLTYFHSVLEGGN"
     CDS             complement(12754..13719)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_24"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 8.2e-119,
                     bitscore: 387.6, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSDLYHVSSSPHVRAKDTTSRIMLYVIIALLPTSLFGIYNFGYKA
                     LVLILVTIASCVASEWVFNKIVHKKQTIDDLSAVVTGLLLALNLPATLPWWEAVIGGVF
                     AIVVVKCLFGGLGQNFMNPALGARCFLLIAFAADMTKFGITKNGIEVYSSVTPLAAMRN
                     GEAVNTMDMLIGRTAGTIGETSAIAILIGAIFLILMGVINLRIPASYIITFAVFMLLFG
                     GHGFDGSYLTAQLCGGGLMLGAFFMATDYVTSPITPMGQIIFGICCGILTGLFRCFGAN
                     AEGVSFAIILSNILVPLIEKHTVPMAFGQVKEAKKQEGGK"
     protocluster    13109..29921
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[29974:35205]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      23109..28339
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="2"
     cand_cluster    13109..29921
                     /candidate_cluster_number="3"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="2"
                     /tool="gutsmash"
     CDS             complement(13752..15071)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4_9"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_25"
                     /sec_met_domain="Fer4_9 (E-value: 1.8e-10, bitscore: 32.4,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1e-08, bitscore: 26.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.7e-15, bitscore: 47.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.9e-54, bitscore:
                     174.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 3.8e-42, bitscore: 133.8,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.3e-05, bitscore: 16.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSKTFKGGVHPYEGKELAKDQPIVEVLPKGDLVYPLSQHIGAPA
                     TPVVAVGDKVLKGQKIAEAGGFVSSPIYASASGTVKAIEPHRVAVGDMVNSIVIENDGA
                     FEEVEYTPCEDVTALSKEEIVNKVKEAGVVGMGGAGFPTHVKLSPKEPEKIEYVIANCA
                     ECEPYLTADYRRMLENPEELIGGMKIILQLFDHAKGVLGIEDNKPDCIEKLTELVKDEP
                     RIEVCPLQTKYPQGGERQLIYAVTGRAINSKMLPADAGCIVDNVETIIAVYRAVKLGRP
                     VTNRISTITGDAIANPGNFLYSIGTSYAELVEAAGGFKTQPEKIISGGPMMGFAMFSLD
                     IPTTKTSSSLLCLSKDEVSKVEPSACINCGRCVEACPEQLIPSRLAKFSNNGLAEAFES
                     WHGLECVECGSCSFVCPARRQLAQSIKTMKKQVLAAKRKK"
     CDS             15487..16596
                     /locus_tag="ctg22_26"
                     /transl_table=11
                     /translation="MITWHEELIFDFSDPVSNEVFTENCIFFDIETTGFSPARTDLYLI
                     GCATRRGSLLCIDQFFSENVADQKNVLSAFLELLSGYDTILTFNGIGFDIPYLKAKCKT
                     LHLSDPFDAHSYIDLYKEVSRFKFLFALTSYKQKSIELFLGIDRIDAYSGGELIEVYKE
                     YVRHPAKDSLALLKQHNYEDVLYMPKLLPVLSYPKLWEQAFSLQSLQASEYRSMDGASG
                     NKELFFTLALQYPVPKPVSFSYDDCYLSMSGSTARLRVRLFEGELRFFYDGSPKDYYYL
                     PEEDIAVHKSIASAVDKEHRVQANASNCYGKKYAIFLPQYDAMFSPVFREQPRGRKCYF
                     ELSADFAADPAMQMDYVLHLLETMRSHRK"
     CDS             complement(16722..17504)
                     /locus_tag="ctg22_27"
                     /transl_table=11
                     /translation="MLETDNYEKFKKDILALAKIDLNSYKEKQMRRRINTLITKNHIAT
                     YDEYVALIKKDKEKFEQFINFLTINVSEFYRNPDQWKILENEVFPKLIQKFGKNLKIWS
                     AACSTGDEPYSLVMALSRHLPLANIKVIATDIDKQVIDTARMGLYNEKSIASVPDDLKK
                     KYFTKVGNSYQISDEIKKRVEFKEHDLLKDPYPGGCNLIVCRNVVIYFTEEAKDEIYAK
                     FYKALATGGVLFIGSTEQIMNYREIGFERDKSFFFEKA"
     CDS             complement(17482..17598)
                     /locus_tag="ctg22_28"
                     /transl_table=11
                     /translation="MIAELQIGLHVGGSLFLYLHHVDNKESRGIKYAGNGQL"
     CDS             complement(17611..18729)
                     /locus_tag="ctg22_29"
                     /transl_table=11
                     /translation="MSEMSFEQMLEESFKTIRNGEVVEGTVIDVKPDEIVLNIGYKADG
                     IITRNEYTNEANVDLTTLVSVGDTMEAKVLKVNDGEGQVLLTYKRLAAEKGSKRLEEAF
                     ENKEVLTAKVAQVLDGGLCVNVDETRVFIPASLVSDTYEKDLSKYKDQEIEFVISEFNP
                     KRRRIIGDRKQLLVAKKLEQQKELFARIKIGDVLEGTVKNVTDFGAFIDLGGADGLLHI
                     SEMSWGRVESPKKVFKVGDQVRVFIKDINENKIALSMKFPAENPWNGAAEKFAIGNVVK
                     GKVARMTDFGAFVELAPGVDALLHVSQISKEHVEKPSDVLKVGQEIEAKIVDFNEEEKK
                     ISLSMKALLAPEEDADADVADVDIDAVAKEEE"
     CDS             complement(18710..19561)
                     /locus_tag="ctg22_30"
                     /transl_table=11
                     /translation="MNVILAKSAGFCFGVKRAVDTVYERILEKEPLYTFGPIIHNEEVV
                     RDLEEKGVVVVNDVDELAGKPQGTVIIRAHGVERGVCEKIQTLGFSIVDATCPFVLKIH
                     RLVERYSGEDCHIVIVGNASHPEVKGIKSWSNAEDTRVIGTREEAEKYDASHGKKVCIV
                     SQTTFNYNKFQELVEIIKEKGYDIIVLNTICNATEERQTEARAIAEQVDAMIVIGGRNS
                     SNTQKLFEICKNECKNTYYIQTVKDLDLAEVRSVDNVGITAGASTPNNIIEEVQKNVRN
                     EL"
     CDS             complement(19567..20229)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_31"
                     /sec_met_domain="Cytidylate_kin (E-value: 1.7e-80,
                     bitscore: 261.1, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMNIAIDGPAGAGKSTIAKKLAKKLAFVYVDTGAMYRAMAYYFL
                     QNGIAPDDEQAIAAACPKVDVTIVYENGEQQVLLNGENVNGVIRTEEVGNMASATSVYP
                     VVRTKLVELQRQLATKTDVIMDGRDIGTCVLPDAQVKIYLTASVATRAKRRYDELTAKG
                     TQCNLEEIEKDIEDRDYRDMHRETSPLKQAKDAVLVDSSEMNIDEVVDAIYQIYARV"
     CDS             complement(20248..21438)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HI0933_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_32"
                     /sec_met_domain="HI0933_like (E-value: 8.7e-128, bitscore:
                     417.8, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFAAIAAAERGHEVVLLEKNEKLGKKLYITGKGRCNITNAGDMDT
                     LFANVMTNPKFLYSAFYDYDNQRVIDFFEENGLATKVERGNRVFPVSDHSSDVIATLQR
                     VLKRTGVMVQLHAEVRQILTGEGAVRGVKLADGSVLEAERVILATGGFSYQTTGSTGDG
                     YRFARELGHTVTQITPSLVPFYVKETCAARMQGLALKNVQVRIRDGKKLLYDEFGEMLF
                     THFGVSGPLILSASAAIKPGRVEKELAMEIDLKPALTEEQLDARLLREFEEAKNKQFKN
                     AVVHLFPAKMIPVMLEAGAIDPEKKVNEITREERMGFVHLIKAFPLTLCGVRDFNEAII
                     TRGGVSVKEVNPSTMESKLVPGLYFCGELLDLDAMTGGFNLQIAWSTGHLAGESIE"
     CDS             complement(21470..22402)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SIS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_33"
                     /sec_met_domain="SIS (E-value: 4.7e-24, bitscore: 76.1,
                     seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNTNDLSNRINDAYSKLSKGQKRLATYITDNYDKAVFLTAAKLG
                     EVVGVSESTVVRFATHLGYKGYPEFQSALEELVRNKLNSIQRMEVTYGRISQSKILETV
                     LKSDADKIHSTLEKIDQNAFELAVDTILHAKHIYIIGIRSCAPLASFMAFYFTLMFPNV
                     HLIQTSSSSEIFEQMVRIGKEDVIIGISFPRYSMRTLKAMEFANNRSAKVITLTDSVHS
                     PMNLYSSCNLIADSDMASIVDSLVAPLSVINALIVALCMKKQNEVAKTLEMLEDIWDEY
                     QVYENDEINYIDDSIKMRYGKVGDAELYE"
     CDS             22564..23046
                     /locus_tag="ctg22_34"
                     /transl_table=11
                     /translation="MRDITPATNFIHTLMQSPPDASAWIAGGNNFPSISGLARFYATDY
                     EGTLVEVEVFGLPNVATPGSSNFYGMHIHENGVCVSPFTSAGAHYSRTPAEHPNHSGDM
                     PPLLGNQGYAWMTFYDKRFTIPEIIGKSLIIHRMPDNFTTQPAGDSGERIACGVIK"
     CDS             complement(23109..24527)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: PYC_OADA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_35"
                     /sec_met_domain="HMGL-like (E-value: 3.1e-45, bitscore:
                     146.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 3.9e-59, bitscore:
                     191.1, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEVVKKPLKITETVLRDAHQSLIATRMTTEQMLPIVDKMDKVGY
                     NAVECWGGATFDACLRFLKEDPWDRLRKLRDGFKNTKLQMLFRGQNILGYRPYADDVVE
                     YFVQKSIANGIDIIRIFDCLNDVRNLQTAVTACNKEKGHAQVALSYTLGDAYTLDYWME
                     MAKKVEDMGADSLCIKDMAGLLVPTKATELIQALKSATNLPIELHTHYTSGVASMTYMK
                     AVEAGCDIIDTAMSPFSMGTSQPATEVMVEAFKGTEFDTGLDQNLLAEIADYFRPMREE
                     ALESGLMNPKVLGVNIKTLLYQVPGGMLSNLLSQLKEQGKEDKFEEVLAEVPRVRKDLG
                     EPPLVTPSSQIVGTQAVFNVLMGERYKVATKETKDVLLGKYGQTVKPFNPEIVDKVLGE
                     EKKNAITCRPADLLEPELDKIEAEMKQWKQQDEDVLSYALFPQVATEFFKYREAQQKKV
                     DASVADTKNGAYPV"
     CDS             complement(24593..25741)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_36"
                     /sec_met_domain="OAD_beta (E-value: 8.8e-157, bitscore:
                     512.8, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYFSETMGNLLHQTAFFNLTWGNFVMIIVACFFLYLAIAKGFEP
                     LLLVPIAFGMLLVNIYPDIFADPEQMSNGVGGLFHYFYVLDEWSILPSLIFLGVGAMTD
                     FGPLIANPISFLLGAAAQFGIFGAYFLAIMMGFNDKAAAAVSIIGGADGPTSIFLAGKL
                     GQSGLMGPIAVAAYSYMALVPIIQPPIMKLFTTKKERAIKMENLRPVSKLEKILFPIVV
                     TVVVCTILPTTAPLVGMLMLGNLFRESGVVRQLTDTASNALMYIVVILLGTSVGASTSA
                     EAFLNTTTLKIVALGLIAFMFGTAAGVLFGKLLCFLTKGKINPLIGSAGVSAVPMAARV
                     SQKVGAEEDPTNFLLMHAMGPNVAGVIGTAVAAGVFMAIFGI"
     CDS             complement(25757..26122)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 61.7; E-value:
                     1.5e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_37"
                     /sec_met_domain="Biotin_lipoyl (E-value: 9.4e-20, bitscore:
                     61.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYTITVNGNVYDVTVEENGAVSAPAAAPRRAAAPAAAPAAKPA
                     AAAGAGSVKIEAGAAGKVFKLEKSVGDAVKKGDSIMVLEIMKMETPVVATQDGTVASIN
                     VSVGDMVEAGALLATLN"
     CDS             complement(26164..26916)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_38"
                     /sec_met_domain="OAD_gamma (E-value: 1.6e-25, bitscore:
                     81.0, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQNRKVKFMKKKLSLILCLCFMALGLAACGTDPTTVDYFGMTYD
                     ELQSSMEQEVSALVGLTDDNRTYIQSYGSDTAMKLVESWDEATSDVGAYQGLGEFNITK
                     AQKTLTVDQYVEYQNREVIVSYIYTYNYETEQPELTDASADKVYTLGEKMEKAALNTLM
                     GMGTVFVVLILISLIIYCFRFISVIQNKAAGKGKKNEAEAGAVVEQIGQREEQLTDDLE
                     LVAVISAAVAASTGASADSFVVRSIRRR"
     CDS             complement(26903..28339)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_39"
                     /sec_met_domain="CT_Vparvula (E-value: 9.9e-125, bitscore:
                     408.3, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSSNDSLAMQRITRLVDENSFIEIGSLVTARSTDFNLAATDTPS
                     DGVITGHGLIDGNLVFIYSQDASVLNGTIGEMHAKKIAAVYDMAMKMGAPVIGFIDCAG
                     VRLQESVDALDGFGLIYAKEVAASGVVPQISAVFGSCGGGLAVVPALSDFAFIEESKGK
                     MFVNSPNAIDGNRIEKCDTSSAAFQADENGCIDATGTEDEILADIRELVGMLPLNNEGD
                     VYTDECADDLNRACESMDAMKGDPRYLLSEISDSHTFFETKAGYARDMVTGFIKLNGMT
                     VGAVANCTTVYDEEGKESEKFDNVLSAKGCEKAAEFVSFCDAFEIPVLTLTNVKGYKAC
                     KCSEKRLAKALAHLTSAFAGATCPKVNLITGEAYGTAYVAMNSKSIGADFVYAWPDAKV
                     GMMDADLAVKIMYADASADELAEKAKEYDALQGSVMTAARRGYVDLIVDPADTRKYLVD
                     AFELLYTKCAYTPDKKHGTK"
     CDS             complement(28524..29921)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_40"
                     /sec_met_domain="Peptidase_S11 (E-value: 3.8e-50, bitscore:
                     161.9, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="NAHIFLQRIFHLHFHMKSPSVFLIILLIKARYAYYGSSLLRAVSV
                     LQKMRDAYTSVKSFWENGMYRRFLSLLLSMSLLIFSPVRVRAQDVPAESELYAKSAVLM
                     DADSGRILYEKNGHEAMANASTTKILTCIVALENCDPASVVTVSKNAASQPKVHLGMHE
                     GQQFYLRDLLYGLMLESYNDCAVAIAEFAAGDVQGFAALMNAKAEELGCEDSYFITPNG
                     LDAKDDAGFHHTTAADLAKIMKYCIKESLKSDEFLGITRTAQYSFSDAEGKCTYQCTNH
                     NAFLQMMEGALSGKTGFTGTAGYCYVGALQREDKTLIVALLACGWPNNKTYKWSDTRKL
                     MNYGLEQFKKIDLLQIEPDETELALIEVRDGQGGQIGETVYLKPVVRNYAGEESILAPL
                     SSEVTLKYEIADRLYAPVKSGDYIGKIRYMLGEETLAERCVVAGETIGKIDYPWCLGQV
                     LRLLWIE"
ORIGIN
        1 atatagtgtt cccgcaccgt cttctgcagt gcctcgtctg tcttcgcatg tcccggggaa
       61 tcaaaggtaa tcatctccct gccatttctg cggaaatagt acccgtcggt aaaaccgctg
      121 cggttgccga gcgccagcag ctttctgtga tcctcctccg ttaccgcgta agccttcttc
      181 gcccgccggc gtgcctcatc ctcgctgcag ctgcccgctc tctcctcatt cagccggtcc
      241 agataacggt ccatatactg ccggtaaacg gatacaacgc ctgccgcata ctccgcctgc
      301 ttcatccgtc cctcaatctt aaaggagaat atgccgctct ctgcaagtgc gggaatggca
      361 tcaatcgtac acagatcctt cgggcttaac acgtaattgc cgcacgcgat acgggatttc
      421 tgatcctttt tgtagacctc atagggaagc cggcacggct gtgcacagcg cccacggttg
      481 ccgcttctgc cgcccagcat actgctgagc agacattgcc cggaataaca gtaacacagt
      541 gcaccgtgca caaaactctc gatctcgatt cccaccttgt catggatttc tcttatctcg
      601 gcaaacgaca tctcccgcgc catgaccacc cggctcgcac cgagctgctt catgtacgcc
      661 gcacccgccg cgccggtcac agtcatctgc gtgctggtgt gaatatccat cctagggaac
      721 atgcttcgta tccttgcaaa cgcccccata tcctgcacga tcaccgcatc gagcccctgc
      781 tcgtaatacg gcagcagata ctcatagagt ccctgttcca gttcctcctc cttgaacagg
      841 gtgttcaccg tcagatacac ctgtctgcca tggatatgtg catagtcgat ggcacgcagc
      901 aattcttcct cattaaaatt attcgcatat gcgcgggctc caaaatggct gccgcccaga
      961 tataccgcgt ccgcccccgc ccgtatgacc gcctcaaacg tctcgtatga tcccgccgga
     1021 gccagcagct ccaattctct tttctgcatc atttttctta cctgttatat gaaaataagg
     1081 gacgaaagca aatctcttac gtccccgtat tgtctattct tctgttttat ctttttccgt
     1141 tactttgccg agcagcgcat cctcgagact cgcctccagc ttagccttgt tgattaaaag
     1201 ctccttgttc tgctcctcga gctcttttct ggctttctcg tcgctctctg ccttgatctg
     1261 attggaaata agatcatgtt tgagatcgta gatttccttt tccttctgct cgatctcacg
     1321 ctcaagcttc tccacctgtg tcttcgcctt aaagtaatca tccgcgatat ttaactgcaa
     1381 cagcgtcgcc ttcatgtcgc cggatagatg tcttaactct tccatgccct gaaactcgcc
     1441 cagcttattg ttgatatagg tggcaacctt ctgtaggtac tcctcgccct cataaccgct
     1501 cagtgtgtat acctttccac cgatgatcac ttcggcgctt gtcttctctg ccataccatt
     1561 tcctccaaac tcgggtatcc gctacaatat atagtatatt atactgacat atttaaggaa
     1621 aagcaactat ttctatacgg aatgttcgat tcccagatgc tggtatgcca gctctgtcac
     1681 cacccgtccc ttcggcgtgc ggttgatcag cccgttcttt accagatacg gttcatatac
     1741 gtcctcgatg gttccggcat cctcaccgat tgctgccgcc agcgtgtcca gcccgaccgg
     1801 tccgcccgca aattttccga tcatcgtcat caaaatgttc ctgtcattct gatcgagccc
     1861 catcttgtca acctccagca gatccagtgc aaaggacgct acctcctttg aaatccggcc
     1921 gtcgtatttt acctgcgcga aatcgcgcac gcgctttaac agccggttcg ccagacgcgg
     1981 ggttccgcgc gagcgtctcg ccatctcgta agcaccctcc tcatcgatct ccaccccaag
     2041 tgtcaatgcc gaatgcagga tgatcgtttt taactcctcc accgtgtaga actccagatg
     2101 atgcaccacg ccaaaacggt ctcttaacgg tgccgacaaa agtcccgcgc gcgtggtcgc
     2161 tcccaccagg gtaaacttcg gcagatccag acggatggag cgcgctgtgg ctcccttgcc
     2221 aagcatgata tcaatggcat aatcctccat tgccgggtac agcacctcct ccacctggcg
     2281 gttcagccgg tggatctcgt cgacaaagag gacatctccc tcctgcagat tgcttaggat
     2341 cgctgccatt tcccccggtt ttccgatggc aggtcccgaa gtgaccttca tatgtgttcc
     2401 catctcattg gcaatgattc cggcgagcgt ggtctttcca agtccgggcg gtccgtagaa
     2461 cagcacatgg tcgagagatt cccccctcgc ctttgccgcc tcgatatata tttttaaatt
     2521 ttcctttgcc ttctgctgtc cgatataatc gtccagcgtc tgcggccgga gacttttctc
     2581 gatcttaaga tcttcctcct gcacctgcgt ggatatgacc cgcttctcca tgtcccagct
     2641 ttcctttctt ccgccttgcc gcttccctta ctacaggaat gccatattct taagcgcggc
     2701 ttttaacagt gtttccacat ccatatcatc cgtgatctca atgccgttta acgcctttaa
     2761 cgcttccgaa gaggcatagc cgagcgccac aagcgcctgc accgcctcat tcttcacacc
     2821 gctgcttccg ttctcgttct gtctgctcac atgctcggat ttgagttcaa acgcctcctc
     2881 aagcgacagc ttgtccttca gttctaaaat cacacgctgt gccgtctttg caccgattcc
     2941 gggcgctttg gcgatcgcct tcgcgtcatc gccaagcacc gcaaatcgca gatcatcggt
     3001 tgtcatcaca gacagcaccg ccagcgcccc cttcgggccg ataccgttga cgccgattaa
     3061 cagcttgaag acacgcaggt catccttcgt caggaacccg tacagaatca tcgcatcttc
     3121 gcgcacattc agatacgtat agagcttgac ttcctctccc acagccggaa gatagtcaaa
     3181 cgtctgcccg gtcgtataga tccggtatcc gattccgcct gcctccacaa ccacgctctc
     3241 ttcttccaca tccgcaagga cgccttttat atatgcgtac acacgtattt cctccttatc
     3301 gtttcagccg tccgccaatc cttagtatga tctcctgggc tgccacaccg atcagcagtc
     3361 ccgtaacgat gcctgccacg aaaagcaccg gcagatagta aaaaatgttg atattctcca
     3421 ccacaaacgc cgccacggca atctgaccga tgttgtgtga cattccgccc gcgacgctga
     3481 ccggcagcac accgagcttt ccggtccgtt tcaaaagata catcaccaga aagctgaaca
     3541 ttccgccggc aaggctgtat aagatactga acagattgcc aaacagaaaa cccgccagta
     3601 caatccggag catcgagatg gcaaacgcct ccttagtgcc gacacagtac agcatcagta
     3661 ccaccacaat attggtgagc cccagcttta cccccggtat tccgaaataa aacgggatca
     3721 gggattccac atagctgcag attaaggcaa gcgcaagaaa aaccccgaga tacgccacct
     3781 tatctcgcaa tggagtcgaa tccgttttct tcacttcccg tcacctccac aaccactttg
     3841 ttcggcagac agacaatcat ctcatgattc ttagagattg ccttctgatg gacacacagc
     3901 ttgtccgggc agtccgcctc cgtcatgtcc gccctgccat cgcggattgt caggacattc
     3961 gttgtcacgc cgtcctgcac aatcggtatc tcctgctcct ccccgagcgc ataggtcccg
     4021 tacacgctgc cgtccacggt gacgcgcaca caggcacccg catccgcgcg cattcccgtc
     4081 cgctcataga tcacaagaaa taccgtaacc acggcaagca gtattgcaag aaaaatcaca
     4141 tcgtttctgc tgattcgctt tttcataccg tctgaccatt tccgtctgcc cgctcgccaa
     4201 ggtaataaaa gccccggcac tcggtcagct ttacatccag aatctttccg atcatgtccg
     4261 ctgtccccgg cagatgtacc accgagttat tgctgagtct tcccgtcaca agcgaagcat
     4321 cctgctcgtt ttgctcttca atcagcaccg gcagcgtctg tccggtcagc gcctccgctt
     4381 tttctgcgga gatcttctgc acttccttaa gcaggcggtc aaaacgcgcc ttgatcacat
     4441 cctccggcac ctgctcttcc atggatgccg ccggtgtccc ggtacgtttg gaatagataa
     4501 acgtgaacgc gctgtcataa cgcacttttc gcaccacgtc catcgtctcc tcgaagtcct
     4561 cctccgtctc ccccgggaat cccacgataa tatccgtcgt cagcgcaatg tccggcactg
     4621 ccgcgcggat cttgtccacc agttccagat aatgttcctt atcatatctg cggttcatga
     4681 tctttaagat ccggctgctc ccggactgta atggcaggtg cagatgtttg cagatctttt
     4741 tggatcgtcc catcacctcg atcagctcgt ccgagagatc cttcgggtgg gaggtcataa
     4801 aacggatacg ctctaacccc tcaatcttct ccacttcctc taaaagctgc gcaaacgtca
     4861 ccggctcctt cagattcttg ccgtaggaat tgacattctg tccgagcagc atgacctcga
     4921 caacgccgtc cgccacgagc tgttcgatct cacggatgat ctctttcggc tccctgctgc
     4981 gctcccttcc gcgcacatac ggtacgatac agtagctgca gaaattattg catccgaaca
     5041 tgatattgac gccggattta aacgaatact tccgctctac cgggaggtcc tccacgatct
     5101 ggtccgtgtc cttccagata tcaatcgtca tggaatccga ttccatcgcc gtcacaatca
     5161 gctctgcaaa tttgtagata ttatgtgttc cgaagatcag atccacaaag cggtagcttt
     5221 cttttaattt ttcaacaact accgtctcct gcatcatgca gccgcagagt ccgatcagca
     5281 tatgtggatt tttcttttta taattctgga gtaccccgag tcttccatag actttgttat
     5341 ttgcattttc acgcaccgtg caggtattgt aaataacaaa atccgcgtcc tccgtatccg
     5401 tctccacata accgatgcgc tctaagatac cgacaagctt ctcagaatcg cgcgcgttca
     5461 tctggcagcc gaacgtcgtg acatgaaagg tcagcggact gccttttttt gcagagagct
     5521 gttccacata atttttagca atgtccataa agtaatactg acgctccggc tcgctctgcg
     5581 ggatctgctt tttatcgatt atttcaatgt ctattttctt tttcatcttc atccttacca
     5641 tctacggacg tgtctgcccg tttccatata taatatattt tgtgctggtc agcgcatcca
     5701 gtcccatcgg tcctcttgcg tgaagcttct gggtactgat gccgatctcc gcgccaaatc
     5761 caaattcaaa tccgtctgaa aaacgcgtcg atgcgttgac atagacgcag gcagcatcga
     5821 tctcatccag gaaccgctgc gcgttcgtgt agttttctgt gatgattgcc tccgaatgcc
     5881 cggtattgta gcggttgatg tgtgcgatcg cctcgtcgag ggacgacacc gtcttcacgg
     5941 agatcatata atcgagatac tccctgcccc agtcttcctc cgtcgccgcc gacaacagtt
     6001 cctttttcag gtctccgcca tttgccgcct cccggcgctc tgccgctgca agacttttct
     6061 catccgcatg aataacaaca tccttctgct gcagtgccgc cgcaagcttt ggcataaatg
     6121 catccacgat tttctcatgg atcacgagtg attcacaggc attgcacaca ccgatccgct
     6181 gggtctttgc gtttaaaata atacggattg ccatatcgaa atccgcactc tcatccacat
     6241 agatatgaca gttgccggtt cccgtctcaa tcacaggaat cgtcgcctga ttgacgacgg
     6301 cgcggatcag ccctgctcct ccgcgcggaa tcagcacatc cacatattcg ttcatcttca
     6361 tgaacgcagc cgccgtctcc cggcttgtat cttcaatcag cgatactgcc gcacgcggaa
     6421 tgccatgtgc ctccaaaact tcctgcagaa ccgaaacaat gacgatattg gacaaaatgg
     6481 cgtcactgcc gccttttaag atcactgcgt tgcccgtctt aaaacacagc gcaaacgcat
     6541 ccaccgtcac attcggtctc gcctcataga tcatgccgac cacaccgagc gggacgcgct
     6601 ttttaccgat cataagaccg ttcgggcgct tcttcatgga aaggacttcg ccgatcggat
     6661 cagcaaggtc tgcaacctgc cgcagcccct ccgccatctg ctccatccgg gatgggttga
     6721 gcatcagacg gtccaacagt ccctcgggca tatgattttc tctgccgcgg gcgagatcct
     6781 tctcattctc gcggataatc tcttcggtat gtgccacaat tgcctctgcc gctgcacgca
     6841 gcacctcgtt cttcgtattc gtgtccagat tgccaatctg tctgctcact tcttttgcgc
     6901 tcttacaaag ttctgtcagt tccatatcct ttccatcctt tctgtcagat ccgatattcc
     6961 cgctcctccg tataaatccg atgcatccgc acgtcggtgg gaagcgccgc aagctgttcc
     7021 tcgatctgcc cttcaaacgc taccgccatg cgggacagct tcggaaacct tgcaaaatag
     7081 cggtcataat aaccgccgcc atacccgtac cggttcccct tacggtcaaa gactagtccg
     7141 ggcaccagca ccaccgcatc ctcttccccg atccgtttgc agctctcatc cggctccatc
     7201 acatgaaagg cgccctcccg caccctggaa agctctctga tccggtaaaa ctccatccgg
     7261 tgtgtgtcct gcattctctt cacctggccg cagtcccgct gcagccgctc ttttgatgta
     7321 accggaagcg ccaccgtctt gccgtccgaa agtgcctgtg ccagaaacgg cagacagtca
     7381 gcctccgcgc cgagcggata atagccgtag atgacagcgc tgttatgata ccagtcagac
     7441 gccgccagcc tctcacagat ctttctgctc ttttcctgca cttcctcctg cggcagttcc
     7501 agccgccatg ctttgtgccg cgcccttatc tgctgacgcg ccttctcctg tgtcagcgct
     7561 gcgtcaggaa agtcctgtct tttttccata cttatctcca aggttctcca cggaaccgtc
     7621 cggattcacc atatcgatat tgttaagctg cgccgccaga tttttcttca catccgcaac
     7681 atactgcttg cgcagcagcg cctgctcctt tttttcttcc tccgtcagcc cttccgcctt
     7741 cgacttgcgg tataacgcat tgattctgtc aatctgttcc tggttcatag tgctcctttt
     7801 cctgtattct taaccgatcg tctccaaaat aaaatcttca atccggaaag attctttctt
     7861 ctttgcctga aaaatggttc ccttaaagga atcatcaaat atatgatgca gaatgcagac
     7921 atccctgccg ttcgcaataa tcatgtctgt tcccgagagc gttgcaatct ttgcggctgt
     7981 cagtttggtc gccatgccgc cggttccaac atcactaccg gtcgaacttt tcgccatgcc
     8041 gtagatcgac gcatccatct cctccaccac ttcaatgagc tttgcatccg gattcttgtg
     8101 cggatcgtcg gtaaaaagcc catcgatatc cgagagcagg atcaaaagat ccgccccgat
     8161 cagagaagcc acgattgccg agagcgtgtc gttgtcgcca aactgcatct cataagtaga
     8221 aaccgtatca ttttcattca caattgggat tgcgccaaga cggaacaatt cgtcgaacgt
     8281 attcttcgca ttctctctcg agacagggtt caccatcgtg ttcttcgtca tcagcacctg
     8341 ccctgccacc tgattgtatt ccgcaaaaag ccgctgatag atcatcatca gccgcgcctg
     8401 gccgaccgcc gcgcatgcct gctttgtcga aatgtccttc ggccgctcat ccatgccgag
     8461 cgtctgtctg cccacggcaa tcgcgccgga gcttaccagg cacacatcca tcccgcggtt
     8521 ccgcagattg cagagttctc ttaccagatg ctccagcttg gtgaaattca gattgcccgt
     8581 ctccccgtaa ttcagtgagg aagatccgat cttgactaca actctctttt tctcattaaa
     8641 atgaaaatgc ttttgttcca tctgtctaac gtccccttta tatgtaacat tttccaatca
     8701 ttcatcccaa atgggcatag agtctcatac tgtattactc tatcatatct tcatcaaaat
     8761 ggcaaattga tgttttcaca ttgtatgaac agaaagttta tggtacattg gatgggaaac
     8821 atcagaaatg gagattttta tgatgagaaa aaagaaggta ctctcctgtc ttctggttcc
     8881 cctgctctct gcaaatctgc tgctctccgg ctgcagccgc acggcggacg aaccggttac
     8941 caagtcagga ttttatttta acaccgtcat ctcggtctcg atctatgaaa aagggagcga
     9001 ggaactgctc gatgactgtt ttgcccttgc gcaaaagtac gagggatatt tttccaatac
     9061 gattccggac agcgatattt ccaaaatcaa cgatgcgggc ggcgctcccg tgacagtaca
     9121 cgacgagacg atcgaacttc ttaagaccgg catcgcatat ggcgacttaa gcggcggcaa
     9181 attcgacatt accatcggcc ggctttccga tctgtgggat atctcgacca aggcactgct
     9241 tgatcagacc gatgcctcca tgatcccctc cgacgcggac attcagacgg ctcttgccac
     9301 agtggattac cgggagattc agattgacgg caacacagtg actctgcaaa atcccgatgc
     9361 caggattgat ctgggcggca tcgccaaagg ctatatcgcg gatcagatga aagcctacct
     9421 gaaccagaag ggaattactt ccggttacat caatctcggc gggaatgtac ttgcgctcgg
     9481 cgcgaagacg gacggttcgg catacaccat cggcatacag cgtccgttcg gtgaggaaaa
     9541 cgaagcgatt gcctccgtct ccatcaccga tcagaccgtc gtatcctccg gcgtctacga
     9601 acgctatttt gaagtagatg ggacgcgtta tcaccatatc ctggacaccg cgaccggtta
     9661 cccttacgat aacgggctcc ttgaggtcac gatcatcacc ggtgcatcgg tggacggcga
     9721 cggtctctcc accacctgtt tctccctcgg gctggaagac ggtatggcgc tcgttgaaag
     9781 ccttgatgct acggaagcta ttttcatcac agacgactat gaagtacaca ccagctccgg
     9841 catgggaacc gtcattccct atgagattct ggaagattaa acaacaaaac aggcgtgaag
     9901 aattcgtact tattaccgcg aattcttcac acctgttttt atttcacact tgcattccac
     9961 gaaacgattc ttacaggatg attttcggag aaaatcattc ttacagaata attttctttg
    10021 gacacttctg tgcacagata ccgcatccga cacacttctc ctgatcaatg tatgccacgt
    10081 tgtcaatgac atgaactgca tccttcgggc agttcttctc acacagatga catccgatac
    10141 atcctacgga acatgccttc atgacatcct tgcccttatc cttggagctg cactgtacaa
    10201 tgtgctttgc cttgtaagga acaagctcga tcagatgctt cggacatgca gcaacacatt
    10261 ttccacatgc cttacatact tccttgtcaa cctgcgcaat gccgtccacg atatgaatcg
    10321 catcaaacgg acaagccttt acacagctac cgtatccaag gcatccgtaa ttacaggact
    10381 tcggtccgcc gttcggcacg aatgccatgg ctgcacagtc ctcgttgccg gtatactcgt
    10441 aatcgcgtcc tgccttctca caggttcccg cacactttac aaatgctacc ttgcgctcgc
    10501 cttcctcggc tgccacaccc atgatctcac cgatcttggc tgctaccggc gcgccgccga
    10561 ccggacactg attgaccgga gcctcgccct ttgcgattgc tgctgccaga ccggaacaac
    10621 cggcataacc acagccacca cagttatttc ccggaagcac acctaagatt gcttcctctt
    10681 tttcatctac ctctaccttg aacttttctc cggaaatacc aaggaaaaat ccaatcaaga
    10741 tacctacgcc gcccacgatt aaggctgcaa ataaaattgc tgtaacgttc atcttctttt
    10801 tcctcctaaa tcattcctga gaatcccatg aatgcgattg acatcagaca tgcggaaatc
    10861 aatacgattg cagtaccctg aaacggcttc gggatatcat tgtactcgat cttctcacgc
    10921 acacctgcca ttaaaacgat cgcaatcagg aaaccaaatg cggttgcaaa accgtttacc
    10981 acgctctcca aaataccgta ttccttggta acattcgtca gtgcaacacc gagaacggca
    11041 cagtttgtcg taatcagcgg aaggtataca ccaaggctct ggtataatgc cggcatggac
    11101 ttcttcaaga acatctcaac gaactgtacc agtgcagcga ttacaagaat aaatacaatc
    11161 gtctgcaggt aggtaaggtc aatgcccttg ctcatcagat agctgttggc aaggatatat
    11221 ttgtagatca gcgctgtcac gaacgaagag atcgtgataa cgaatacaac tgcgccaccc
    11281 attccggcag cggtctctgt tttcttggaa acgcctaaaa acggacagat accaaggaac
    11341 tgacttaata caacgttatt gacaatggca gagccgattg caattaaaag taatgttttc
    11401 atccgtatct atcctcctat tctgcttttt ctgccggagc ttccgctgcc ggtttcttac
    11461 cggtgcatgc agcagacata ccgcatcctg cacagtctcc ggtgatacat ccggacggct
    11521 cggcaagcgg cttgcccttg gctgccatct tctcacggac gatcttcatc acagctacca
    11581 gacatgccag tacgaggaat gctcccggtg ccataacaaa gatggtgatc ggtgtgaacc
    11641 agcttaagga cagaatctgg aaaccaaaga tctgacctgc gcccagaagc tcacggaaca
    11701 gtccgatcag ggtaagaccc atcgtaaatc caagtcccat accaagtcca tcgaaaagag
    11761 acggaactac cggattcttg gaagcatagc tctcagcacg gccgaggata atacagttta
    11821 caacgattaa cgggatgtac acacccagcg actcggagag gctcggggta tacgcctgca
    11881 tgataaactg caccactgtt accagcgatg caacgataac aatgtatgcc ggcatacgca
    11941 cgccgtccgg aatcacctta cggaatgcgg aaatcagcat attggaaagt accagtacca
    12001 ctgttgtgga aagtcccatg ccaagtccgt tgattgcgga ggatgtgaca gcaagtgtcg
    12061 gacacatacc aagcatcaga acgaaagtag gattttcctt aatgagtcca ttatataaac
    12121 gttctacatt cttgttcatt gattagttac ctccttctaa tacgctgtgg aagtatgtaa
    12181 ggcaggcatt cacaccgttc gccatcgcct tggaagtaat ggtggaaccg gaaattgcct
    12241 cgatctcatt gtccgcagac ggtgtcgact tcacaaccgt aaaggagtct acgttcttgc
    12301 cctcaaactg gctgtagaac ggctcttcct gtgctttcat accaagtccc ggtgtctcgg
    12361 aaatacttgt gatggaataa ccgttgaccg taccgtcatt ctggatgccg acagagaatg
    12421 taatgctgcc ctggcttccg tccttcgccg ttacggtaag cacatagccg agcggattgc
    12481 cggaagcgtc aagtgctgtg ttgacagcct cgatatcgtc agaatatcca ttctgcgcca
    12541 taagatcttc cgctgcagcg gtgtcgaaat cagcgtactc ctcaaaggaa tccgcatcct
    12601 caaatacctg cttgtaagcg gactgtgtct tctcataatt tacctggtcg atcgggcctt
    12661 tggtaatgcc gtagaccacg ccgaggatca gacctaatac aacagtaaaa gcaaataaaa
    12721 ccaatgcgtc atgtacaatc ttcttgttca tttctatttg cctccttcct gcttcttcgc
    12781 ttccttcacc tgaccgaatg ccatcggcac cgtgtgcttc tcaataagcg gcacaaggat
    12841 attgcttaag atgatggcga aggaaacacc ctctgcattc gcgccgaagc agcggaacaa
    12901 tccggtcagg ataccgcagc agataccaaa gatgatctgc cccatcggtg taatcgggga
    12961 tgtcacataa tccgttgcca tgaagaatgc gccgagcatc agaccgccgc cgcaaagctg
    13021 tgcggtaaga tagctgccgt caaatccatg accgccgaat aaaagcatga atacagcaaa
    13081 tgtaataatg taagatgccg ggatgcgaag gttgatcaca cccatcagga tcaggaaaat
    13141 agctccgatc aggatagcga tcgcagatgt ctcaccaatg gtacctgcgg tgcgtccgat
    13201 cagcatatcc atcgtattga ccgcctcacc gttacgcatg gcagcaagcg gtgttacgct
    13261 ggaatacact tcaatcccgt tctttgtgat gccgaacttt gtcatatcag cagcaaatgc
    13321 aatcaaaagg aagcatcttg cgcccagcgc cgggttcatg aaattctgtc ccagtccgcc
    13381 aaacagacat tttacaacca cgattgcaaa cacaccgccg attaccgcct cccaccacgg
    13441 aagggttgcc ggaaggttca atgccagaag cagtcccgtt acaacagcgc tcaggtcatc
    13501 gatcgtctgc tttttatgta caatcttatt aaatacccac tctgatgcca cacagcttgc
    13561 aatcgttacc agaatcagaa ccaatgcctt atatccgaaa ttgtaaattc cgaacaggct
    13621 tgtcggaagc aatgcaataa tcacatacag cataatacgg cttgtggtat ctttggcacg
    13681 aacgtgtggt gatgatgaaa catgatataa atcactcacg ataatccacc tctctcttct
    13741 tgttttttga attatttttt gcgttttgca gcaagtacct gctttttcat cgtcttaatg
    13801 gactgtgcga gctgtctgcg tgcagggcat acaaaactgc agcttccgca ctccacgcac
    13861 tcgagtccgt gccaggattc aaacgcctca gccagaccgt tattggaaaa cttggcaagt
    13921 cttgacggta tcagctgctc cgggcatgct tccacacagc ggccgcagtt gatacatgcg
    13981 gacggctcca ccttggacac ttcgtccttg cttaagcaaa gcagtgagga agatgtcttt
    14041 gtcgtaggaa tatccaggct aaacattgca aatcccatca tcggaccacc ggaaataatc
    14101 ttctccggct gtgtcttaaa tccgccggca gcctccacca gttctgcata gctggtaccg
    14161 atgctgtata agaagttgcc cgggttggca atggcatcgc ctgtaatcgt agaaatacga
    14221 ttggttaccg gtctgccaag ctttaccgca cggtaaacag caatgatggt ctccacatta
    14281 tccacgatac atcctgcatc tgccggaagc atcttggaat tgatggcgcg gcctgtcact
    14341 gcataaatga gctgacgctc accaccctgc gggtacttgg tctgtaaagg acagacctca
    14401 attctcggtt catccttgac aagctctgtc agcttttcaa tacaatccgg cttgttgtcc
    14461 tcgatgccga gaacaccctt cgcatgatcg aacagctgga gaatgatctt cattccaccg
    14521 atcagttctt ccggattttc gagcattctg cggtagtccg ccgtcagata cggctcacac
    14581 tctgcgcagt ttgcaattac atattcaatc ttttccggct ctttcggaga cagcttcaca
    14641 tgtgtcggga aacctgcacc gcccatgccg acaacgcctg cctcttttac cttattgaca
    14701 atctcctcct tggagagagc cgtcacgtct tcacacggcg tgtactccac ctcttcaaac
    14761 gccccgtcgt tctcaatgac gatggaattc accatgtcac cgactgccac acggtgcggt
    14821 tcgattgcct ttactgtacc ggatgccgac gcatagatcg gggatgacac aaagccacct
    14881 gcctctgcga tcttctgtcc tttcagcacc ttgtcaccaa ccgctaccac cggagtcgcc
    14941 ggtgcaccga tatgctgtga caacgggtat accagatcac ccttaggtag aacttctacg
    15001 atcggctgat cctttgccag ttcctttcct tcataaggat ggacgccgcc tttaaatgtc
    15061 ttagaaccca tttctcgtgc cccactttct cttatctata ttatattcta tgccaaaagt
    15121 catagaatac cctcgtgtag attatagcac aatcactcgg aaattgtagc aatttattgt
    15181 attttttcac gaacctattg acaaagaatt cacaatattt tttccccatt tatgttataa
    15241 tgtacgtgaa ggcaaaagtg agcatggagc aaaaacatac gctcatgctt gcatgcagcg
    15301 gatggttctg ctccatgtga acgcgcccgc gagtccggga agccgcaggc tttccggact
    15361 tttgccgaag cgtacattgc tatttgccgc gaacgcccgc gagtccggga aatctatgcc
    15421 tttccagacc tgcacagcgg caaaattgga actcttaccc taatattaca tacagaggat
    15481 tttcagatga taacctggca tgaagaactg atttttgatt tttcagaccc cgtttccaac
    15541 gaggtattta cagaaaactg catttttttt gatattgaga caaccggctt ctcgccggcg
    15601 cgcacggatc tctacctgat cggctgcgcc acaaggcgcg gcagtctttt gtgcatcgac
    15661 cagttctttt ccgagaacgt cgccgatcag aaaaatgtcc tttccgcctt tctggagctc
    15721 ttgtccggct atgataccat tctgacgttc aacggtatcg gcttcgacat tccatacctg
    15781 aaggcgaaat gcaagacgct gcacctttcc gatccgtttg atgcgcacag ttatatcgat
    15841 ctttataagg aagtctcacg tttcaaattt ctgtttgccc tgaccagcta caagcaaaaa
    15901 tccatcgaat tgtttctcgg gatcgaccgc atcgatgcct actccggcgg cgagctgatc
    15961 gaagtctaca aagagtacgt gcggcatccc gcaaaggatt cccttgcact gctgaaacag
    16021 cacaactatg aggacgttct ctatatgccg aagcttctgc ccgtcctctc ctacccgaaa
    16081 ctctgggaac aggcattttc gctgcagtcg ctccaggcgt ccgagtaccg gtcgatggac
    16141 ggtgcctccg gcaacaagga gctgtttttt acactggcgc tgcagtaccc cgttcccaaa
    16201 ccggtctcct tctcctacga tgactgttat ctctccatga gcggaagtac cgcccggctg
    16261 cgcgtgcgtc tcttcgaggg agaactgcgc ttcttttatg acggcagtcc caaagattac
    16321 tactatctcc ccgaggagga tatcgcagtt cacaagagca ttgcttctgc tgtcgacaag
    16381 gaacaccgcg tacaggcaaa cgcttccaac tgctacggca aaaaatatgc catctttctt
    16441 ccgcagtatg acgccatgtt ttccccggtg ttccgtgaac agccgcgcgg caggaaatgc
    16501 tattttgaat tatccgcgga ctttgccgcc gatcccgcta tgcagatgga ctatgttctg
    16561 catctgttag aaaccatgcg ttcccaccgc aaataaacac atggcagaaa gccctgatat
    16621 aattaccacc aaaaacggca ggaaagaatc tggcatatac tgcacagctt ctttcctgcc
    16681 gcttttttgc tttatagaaa aatgcgttct ctgaagtaac cttacgcctt ctcaaagaaa
    16741 aaggacttgt ctctctcaaa tccgatctcc cggtaattca tgatctgctc cgtgcttccg
    16801 atgaaaagca cgccgcctgt tgcaagcgcc ttatagaact tcgcataaat ctcgtccttt
    16861 gcctcctcgg taaaatagat cacaacattc cggcacacaa tcagattgca tccgcctgga
    16921 tacggatctt ttaaaagatc atgctccttg aattccacac gtttcttgat ttcatccgag
    16981 atctgatacg aattgccgac cttggtaaaa tacttcttct tcaagtcatc cggcacactc
    17041 gcaatactct tctcattgta gagtcccatc cgcgccgtat caatcacctg cttgtcaatg
    17101 tcggtcgcaa tcaccttgat gtttgcaagc ggcaggtgtc tggacaatgc cattaccagc
    17161 gaatacggct catctccggt cgagcaggca gcactccaga ttttcagatt cttgccaaac
    17221 ttctgaatca gcttcgggaa tacctcattc tccagaatct tccactgatc cggattgcgg
    17281 taaaactccg acacattgat ggtcaggaaa ttgataaact gttcaaactt ctctttgtcc
    17341 ttcttgatca gcgccacata ctcatcatat gtcgcaatat gattcttcgt aatcagcgtg
    17401 ttgattctgc gccgcatctg cttttcctta taagaattca gatcaatctt tgcaagcgct
    17461 aaaatatcct ttttaaactt ttcataattg tccgtttcca gcatatttta tccctcggct
    17521 ctctttgtta tctacatgat gcaaatacag aaataggctt ccaccaacgt gcaagcctat
    17581 ctgtaactct gcaatcatcg aaatcagaga ttactcctct tcctttgcaa ccgcatcaat
    17641 atctacatct gcaacatctg catccgcatc ttcttccggt gcgagcagtg ccttcataga
    17701 taaactgatc ttcttctctt cctcgttgaa atcaacgatc tttgcctcga tctcctgtcc
    17761 aacttttaat acgtcggacg gcttctctac atgctccttg gaaatctggg atacatgaag
    17821 gagtgcatcc acccccggtg caagctcaac aaatgcgccg aagtctgtca ttcttgcaac
    17881 tttgcccttt acaacgttgc cgattgcgaa cttctctgct gcgccgttcc acggattctc
    17941 tgccgggaac ttcatgctga gtgcaatctt attctcattg atatccttga tgaatacgcg
    18001 aacctgatcg cctaccttga ataccttctt cgggctctct actctgcccc aggacatctc
    18061 ggaaatatga agcagaccgt ctgctccgcc aagatcaata aacgcaccga aatctgttac
    18121 attcttaact gttccctcta atacatcacc gatcttgatt cttgcgaaca gttctttctg
    18181 ctgctctaac ttcttagcaa ccagaagctg ctttctgtca ccgatgattc ttcttctctt
    18241 cggattgaac tcgctgataa cgaactcgat ctcctgatcc ttgtatttgg aaagatcttt
    18301 ctcgtaggta tctgatacaa gacttgccgg aataaatact cttgtctcat ctacgtttac
    18361 gcataatcct ccatccagta cctgtgcaac cttagcggtc agcacttcct tgttctcaaa
    18421 tgcttcctct aatctcttgc ttcccttctc ggcagccaga cgcttgtatg tcagtaatac
    18481 ctgaccctca ccgtcattta cctttaaaac ctttgcttcc atggtgtcgc cgacggatac
    18541 caatgtggta aggtctacgt ttgcttcgtt tgtgtattca ttacgagtaa tgattccgtc
    18601 tgccttgtag ccgatattca gaacgatctc atcaggtttc acatcgataa cggtaccctc
    18661 aactacctct ccatttctta ttgttttaaa tgattcttcc agcatttgtt caaagctcat
    18721 ttctgacatt cttttgaacc tcctcaataa tattgtttgg ggtagaagcc cctgcggtaa
    18781 tacctacgtt atcgacagac ctgacttcgg caaggtcaag atcctttaca gtttgtatat
    18841 agtaagtatt tttgcattcg tttttacata tttcaaatag cttctgcgtg ttggagctgt
    18901 tcctgccacc gatcacaatc atggcatcca cctgctccgc gattgcccgg gcttccgtct
    18961 gacgttcctc cgtagcattg cagattgtat ttaaaacaat tatatcataa cctttttctt
    19021 ttataatttc aactaattct tgaaatttat tgtaattaaa tgtcgtttgt gatacaatac
    19081 ataccttttt cccatgggaa gcatcgtatt tttcggcctc ttcgcgggtt ccgatcacgc
    19141 gcgtatcctc tgcattcgac cagcttttga tgccctttac ctccgggtgg ctggcattcc
    19201 cgacgatcac aatgtgacag tcctccccac tgtagcgctc caccagccgg tgaatcttta
    19261 acacaaacgg gcaggtcgcg tccacgatgg aaaagccgag cgtctgtatt ttctcgcaga
    19321 cacctctctc cacgccgtgt gcccggatga ttaccgtccc ctgcggcttc cccgcaagtt
    19381 cgtccacatc gtttaccacg acgacgccct tttcctccag atcgcgcacc acttcttcat
    19441 tgtggatgat cggtccgaac gtgtagagcg gttctttttc cagaatccgt tcatataccg
    19501 tatccacggc acgttttacc ccgaagcaga agcccgcact ctttgccaag attacattca
    19561 tattctctat accctcgcat aaatctgata gattgcgtcc accacttcgt cgatgttcat
    19621 ctcggagctg tccactaaca ccgcatcctt ggcctgcttt aacggcgatg tctcccggtg
    19681 catatcgcgg taatcgcggt cttcaatatc tttctcgatc tcttccagat tgcactgggt
    19741 tcccttggcg gtcagttcat catatctgcg ctttgcgcgc gttgcaacgc ttgccgtgag
    19801 atatattttt acctgcgcat ccggaagcac acaggtgccg atatcccttc cgtccatgat
    19861 gacgtccgtc tttgtcgcaa gctgccgctg cagttccaca agctttgtgc gcacaaccgg
    19921 atagacactg gtcgctgatg ccatattgcc gacttcctcc gtccggatga cgccgtttac
    19981 attctctccg tttaagagca cctgctgttc gccgttctca tacacaatcg tcacgtcaac
    20041 cttcgggcag gctgccgcaa tcgcctgctc atcatctggt gcaatgccgt tctgtaaaaa
    20101 atagtatgcc atcgcacggt acattgctcc cgtatccaca tagacaaacg ccagcttttt
    20161 cgccagtttt ttcgcaattg tgctcttccc ggcgcctgcc ggtccgtcaa tcgcaatatt
    20221 catactcatc tcttcttctc tcctcttcta ttcgatactc tcacccgcca gatgcccggt
    20281 cgaccaggca atctgcagat taaatccgcc ggtcatcgca tccagatcca atagttcccc
    20341 gcagaaatac aatcccggca caagctttga ttccatcgtg gaagggttca cttcctttac
    20401 gctgacaccc ccgcgtgtga tgatcgcttc attgaaatct ctgacaccgc agagcgtcag
    20461 cggaaacgcc ttgatcagat gcacaaatcc catccgctcc tctctcgtga tctcgttgac
    20521 cttcttctcc ggatcaatcg ctccggcttc taacatcacc ggaatcatct tcgccgggaa
    20581 cagatgcacg acggcgtttt taaactgctt attctttgcc tcctcgaatt cacgcagaag
    20641 tctcgcatcc agctgttcct ccgtgagtgc cggctttaag tcgatctcca tcgccagttc
    20701 cttctccacg cggcccggct tgattgccgc actggcgctt aaaatcagcg gtccgcttac
    20761 cccgaaatgg gtaaagagca tctcgccgaa ttcgtcatac aacagctttt ttccgtcccg
    20821 gatgcgcacc tgcacatttt tcagcgccag cccctgcatc ctcgccgcgc aggtctcctt
    20881 cacgtagaac ggaaccagtg acggcgtaat ctgtgtcacc gtatgtccga gttccctcgc
    20941 aaaacggtag ccgtctccag tcgaaccggt cgtctgataa gaaaatcctc cggttgcaag
    21001 aatcacgcgc tctgcttcaa gaacgcttcc gtcggcaagc ttcacgccgc gcaccgcgcc
    21061 ttccccggtg aggatctgcc gcacttccgc atgaagctgc accataacac ccgtgcgctt
    21121 tagtacccgc tgcagcgtgg cgatcacatc cgaagaatga tccgataccg ggaatacacg
    21181 gttgccgcgc tccaccttcg tcgccagacc attctcctca aaaaaatcaa tcactctctg
    21241 attgtcataa tcgtaaaaag cgctgtataa aaacttcggg ttcgtcatca cattggcaaa
    21301 cagggtgtcc atatcccccg cattcgtgat gttgcaccgc cctttgccgg tgatgtagag
    21361 ctttttccca agcttttcat ttttctcgag caaaacgacc tcatgtcccc gctccgccgc
    21421 cgcaatggca gcaaacattc ccgccggccc gccgccgact acgatcacct tactcataca
    21481 gttccgcatc tcctactttt ccataccgca tcttgatgga atcatcgata taattgatct
    21541 catcgttctc ataaacctgg tattcgtccc agatatcctc taacatctca agcgttttcg
    21601 ccacctcgtt ctgctttttc atgcagagcg ccacaatcag cgcattgatc accgacagcg
    21661 gggcaaccag ggaatccaca atggaagcca tatcgctgtc cgcaatcaga ttgcaggaag
    21721 aatagaggtt catcggggaa tgcacgctgt cggtgagtgt gattaccttc gcactccggt
    21781 tattcgcaaa ttccatcgcc tttaaagtac gcatggaata acgcggaaaa ctgattccga
    21841 tgatcacatc ctccttgccg atgcgcacca tctgttcaaa aatctcgctc gaactgcttg
    21901 tctgaatcag atgaacgttc ggaaacatca gggtaaaata aaaagccatg aagctggcaa
    21961 gcggcgcaca gctccggatt ccgatgatat agatatgttt ggcgtgcagg atcgtgtcaa
    22021 ccgcgagttc aaatgcgttc tgatcaatct tttccagtgt ggaatgaatc ttgtccgcat
    22081 cggatttcag caccgtctcc agaatcttcg actggctgat cctgccgtaa gtaacctcca
    22141 tgcgctgaat ggagttcagc ttattgcgca ccagttcctc cagcgcactc tggaattccg
    22201 gatacccctt atatcccaga tgcgttgcaa agcgcaccac cgtggactcg ctcacaccta
    22261 caacctcgcc cagctttgca gcggtcagaa ataccgcctt gtcataattg tccgtaatgt
    22321 aggttgccag ccgtttctgt cccttgctca gcttactgta agcatcattg atgcggttac
    22381 tcaggtcatt tgtattgctc atgcttctcc tcacttctgc ggaattgtga tccgcccaat
    22441 gtttttatta tatcaaatac attgtgtttt gcaagaaatt atgcatggaa ctttcctcac
    22501 atgcagcgca tttttccgcc gctgcatata ataaaccaat aacactcttc cattgaggca
    22561 gctatgcgcg atatcacacc agcaaccaat tttattcata cactgatgca gtctccgccg
    22621 gatgcatccg cctggattgc cggcggcaac aattttcctt ccatctccgg gcttgcccgg
    22681 ttctatgcca cagactacga aggaactctc gtggaggttg aagtcttcgg tcttccgaac
    22741 gtcgcgactc ccggctccag taatttttac ggcatgcaca tccacgaaaa cggcgtgtgc
    22801 gtctccccgt ttaccagtgc cggtgcccat tacagccgta cgccggccga acacccgaat
    22861 cacagcggcg acatgcctcc gcttctgggc aaccagggtt atgcctggat gacattttat
    22921 gacaagcgtt ttacaattcc ggaaatcatc ggaaaatccc tcatcattca ccggatgccg
    22981 gataacttta caacgcagcc cgcgggcgac tccggcgaac ggattgcctg cggtgtgata
    23041 aaatagcaaa aaaggcagca aaaaagcagg tgactactca cccgcttttt gttttaactg
    23101 ttttttgatt ataccggata tgctccgttc ttggtatctg cgacgcttgc atcgactttc
    23161 ttctgctgcg cctcacggta cttgaagaat tcggttgcaa cctgcgggaa cagtgcgtag
    23221 gagagtacat cctcatcctg ctgcttccac tgcttcatct cagcctcgat cttatccagc
    23281 tccggctcaa gcagatctgc cggacggcag gtaatggcgt tcttcttctc ctcgccaagt
    23341 accttgtcta cgatctccgg gttgaacggt tttacagtct gaccgtactt tccaagcagt
    23401 acgtctttgg tctccttggt tgccactttg tagcgctctc ccatcagtac gttgaacaca
    23461 gcctgtgtac caacgatctg tgaggacggt gtaacaagtg gcggctcacc gaggtcttta
    23521 cgcacacgcg gaacctctgc aagaacctcc tcgaacttgt cttccttacc ctgctctttt
    23581 aactgagaca gaaggttgga taacatacca cccggtacct gatataacag agtcttgatg
    23641 ttaacgccga gaaccttcgg gttcatcaga ccgctctcta acgcttcctc acgcatcgga
    23701 cggaagtagt cagcgatctc agctaacagg ttctgatcca gaccggtatc gaactctgtg
    23761 cccttgaatg cctctaccat aacctcggtt gccggctggc tggttcccat ggagaacgga
    23821 gacattgctg tatcgataat gtcacagcct gcctcaaccg ccttcatgta tgtcatggaa
    23881 gcgacaccgg aagtatagtg tgtatggagc tcgatcggaa ggttggttgc agactttaat
    23941 gcctgaatca gctcggttgc cttcgtcgga accaaaagac ctgccatatc cttgatacat
    24001 aaggaatcag cacccatatc ctctaccttc ttcgccatct ccatccagta atccagagtg
    24061 taggcatcgc caagtgtata ggataatgcg acctgtgcat gtcctttttc tttgttacat
    24121 gcggtaacgg ctgtctgcag gttgcggaca tcgtttaagc agtcgaaaat acgaatgata
    24181 tcaataccgt ttgcgatcga tttctgtacg aaatactcta ccacatcatc tgcatacgga
    24241 cgatatccta agatgttctg tccacgaaac agcatctgaa gcttggtgtt cttaaatccg
    24301 tctcttaact tgcggagacg atcccacgga tcttccttca ggaaacgaag gcatgcatcg
    24361 aaggtagcac cgccccagca ctcaaccgca ttgtatccga ccttatccat cttgtctacg
    24421 atcggaagca tctgctcggt tgtcattctt gtcgcaatca gggactggtg cgcatcacgc
    24481 agcaccgtct ctgttatttt taaaggtttt ttaacaactt ctgacatttt ttcctcctta
    24541 tcagcggata ctttgatacc gctatccgtc tatgacggca tttgctcttt cactaaattc
    24601 cgaaaattgc catgaataca ccggctgcta ctgcagtacc gataacgccg gcaacgttcg
    24661 gtcccatcgc atgcatcagc aggaagttcg tcggatcttc ctccgcgccg actttctggg
    24721 atacacgggc tgccatagga acggcagata caccggcaga tccgatcaga ggattgatct
    24781 tgccctttgt gaggaagcat aacagcttac caaacaggac accggctgct gtaccgaaca
    24841 taaatgcaat cagtccaagt gcaacgatct ttaatgtcgt tgtatttaag aacgcctccg
    24901 cactcgtaga tgcacctacg gaagtaccga gcaggataac tacgatgtac atcaatgcgt
    24961 tggatgcggt atcggtcagc tggcggacca caccgctctc gcggaacagg ttaccgagca
    25021 tcagcatacc aaccagcggc gctgtcgtcg gaagaatcgt acatacaacc accgtaacca
    25081 cgatcgggaa gagaatcttc tccagcttgg aaaccggtct taagttctcc atcttgatgg
    25141 cacgctcttt tttggttgta aacagcttca taattggcgg ctggatgatc ggcacaagcg
    25201 ccatatagga atatgccgcc acagcgatcg gtcccatcag tcccgactgt cctaactttc
    25261 cggcaaggaa aatggaggtc ggtccgtcgg ctccaccgat gatggaaaca gcagctgctg
    25321 ccttatcatt aaagcccatc atgattgcaa ggaagtacgc tccgaaaata ccgaactgag
    25381 ctgcagctcc aagcaggaaa ctgatcgggt ttgcaatcag cggtccgaaa tctgtcatag
    25441 caccgactcc aaggaaaatc agagacggta agattgacca ctcgtctaac acataaaagt
    25501 agtggaataa accacctaca ccattgctca tctgctccgg gtctgcaaaa atatccggat
    25561 agatatttac aagcagcata ccgaatgcaa tcggaacaag aagcaatggc tcaaacccct
    25621 tcgcgatagc cagatacagg aaaaagcatg cgacaatgat catcacaaaa tttccccagg
    25681 taaggttaaa gaaagcggtc tgatgcagga ggttccccat tgtctcacta aaatagctca
    25741 ttgtcttcct cctaaattag tttaatgttg caagtaatgc gcccgcttct accatatctc
    25801 caacacttac gttgatactt gctaccgtac cgtcctgcgt tgcaacgacc ggagtctcca
    25861 tcttcatgat ctcaagaacc atgatgctgt ctcccttctt aacggcatca ccgacagact
    25921 tctcaagttt gaataccttt cctgctgcgc ctgcctcgat cttaacgctg cctgcgcctg
    25981 ctgcagcagc cggctttgct gcaggtgctg ccgccggtgc tgctgcacgt ctcggtgctg
    26041 ctgccggtgc gctcactgcg ccgttctctt ctacggttac atcatataca ttgccgttta
    26101 ctgtaattgt atagcttttc attgaaatat cctcctaata tgatttcttt tcatttatac
    26161 gaattagcgt ctgcggatcg atctcacaac gaaagaatcc gcggatgcac cggtgcttgc
    26221 cgcaaccgct gcggaaataa ctgccacaag ttcaagatca tcggtaagct gctcttcacg
    26281 ctgtccgatc tgctctacca cagcgcctgc ctctgcctcg ttcttcttgc ccttgccggc
    26341 cgccttgttc tgtattacag agataaagcg gaaacagtaa ataataaggc tgatcaggat
    26401 tagaaccacg aatacggttc ccattcccat cagggtattt aacgcagcct tctccatctt
    26461 ctcacccagc gtatatacct tgtccgcgga tgcatcagta agctccggct gctcggtctc
    26521 gtaattgtat gtatagatgt aagaaacgat gacttcacga ttctgatact ctacatactg
    26581 atctactgtt aaggttttct gtgcctttgt gatattgaat tctccaagtc cctgatatgc
    26641 gccgacatca cttgtcgcct catcccagct ctcgacaagt ttcattgccg tatcgctgcc
    26701 gtaggactgg atataggttc tgttgtcgtc cgtaagacca accagcgcgg aaacttcctg
    26761 ttccatgctg ctctgcagtt catcgtaagt cattccgaaa tagtcaaccg ttgtcggatc
    26821 tgttccgcat gctgcaagtc ccagagccat aaagcaaaga caaagtataa gagataattt
    26881 tttcttcata aacttcacct ttctattttg ttccatgttt cttgtccggt gtatatgcac
    26941 actttgtgta taacagttca aacgcatcta ccagatactt tctcgtatct gccggatcaa
    27001 cgatcagatc cacatagcct cttctggctg ctgtcataac gctgccctgc agtgcatcat
    27061 attcctttgc cttctctgca agctcatccg cagatgcatc cgcgtacatg atctttactg
    27121 caagatccgc atccatcatg ccgacctttg cgtccggcca tgcatatacg aaatccgcac
    27181 cgatagactt ggaattcata gcaacataag cggtaccgta tgcctctccc gtgatcaggt
    27241 tcaccttcgg acatgtagct cccgcaaatg cggaggtcag atgagcaagt gcctttgcaa
    27301 gacgcttttc agagcacttg catgccttgt agcccttgac attcgtcaga gtcagtaccg
    27361 gaatctcgaa tgcgtcgcag aaagatacga actctgctgc cttctcacat ccctttgcag
    27421 aaagaacatt gtcaaacttc tcgctctctt tgccctcttc gtcgtatacc gttgtgcagt
    27481 ttgcaactgc gccgaccgtc ataccgttta acttgataaa tccggtcacc atatctctgg
    27541 catagcctgc ctttgtctcg aagaatgtat ggctgtccga aatctcactg agaagatatc
    27601 tcggatcacc cttcatggca tccatgctct cgcatgcacg gttcaggtca tccgcacact
    27661 cgtctgtgta gacatctccc tcgttgttga gcggaagcat gccgaccagc tcacggatgt
    27721 ctgcaaggat ctcatcctct gttcccgtcg cgtcgatgca gccgttctca tctgcctgga
    27781 atgccgcaga tgatgtgtcg cacttctcga tgcggtttcc gtcaattgcg ttcggagaat
    27841 tcacaaacat ctttcctttg gattcttcga taaaagcaaa atcagaaagt gccggtacca
    27901 ctgccagtcc accgccgcag ctgccgaata cggctgaaat ctgcggaacc acgccggatg
    27961 ctgcaacttc ttttgcatag atcagtccga agccgtcaag cgcatctaca gactcctgta
    28021 aacggactcc cgcgcaatcg ataaagccga tcaccggtgc tcccatcttc atcgccatgt
    28081 catacactgc agcgatcttc ttcgcatgca tctcgccgat tgttccgttt aaaacagaag
    28141 cgtcctggct gtaaatgaac accagattgc cgtcaatcag gccgtgtcct gtgatgactc
    28201 cgtcggaagg agtatccgtt gctgcaagat taaaatctgt gcttcttgcg gttacgagag
    28261 aaccgatctc aatgaaactg ttctcgtcga ctaacctggt gatgcgctgc atagccaggc
    28321 tatcattgct actattcatt ctttttgccc tccatctata aattgttgtc cacatccatt
    28381 tgggatgcgg cttcatagtg aatgatgtaa atccatgcgt ctttgtataa aaattcaaca
    28441 aattacgcta tgttaaatta taattgcttt tctgcaatat ttcaagtaaa ttgttaattt
    28501 tttgacgctt ttgtttgtgt tttttattcg atccagagaa gccgaagcac ctgccccaga
    28561 caccacggat aatcgatctt tccgattgtc tccccggcta ccacacatcg ctccgcgagc
    28621 gtctcctccc ccagcatata acgaatcttt ccgatgtaat ctccgctctt caccggtgca
    28681 tacagccggt ctgcaatctc atacttaagc gtaacctcac tgcttagcgg cgccaggata
    28741 ctctcctccc ctgcatagtt cctgacaacc ggttttaaat acaccgtttc gccgatttgt
    28801 ccgccctgtc cgtcccgcac ctctatgagc gcaagttccg tttcgtccgg ctcaatctgc
    28861 aacaggtcga tctttttgaa ctgctccaat ccgtaattca tgagttttct ggtgtcggac
    28921 cacttatagg tcttgttgtt cggccatcca caggcgagca gcgccacgat cagcgttttg
    28981 tcctcccgct gcagcgctcc gacatagcag tatccggcgg ttccggtaaa tcccgttttt
    29041 ccggaaagcg ccccttccat catctgcaaa aatgcattgt ggttcgtgca ctggtacgta
    29101 catttcccct ctgcatcaga aaaagaatac tgcgccgttc gtgtaatccc gagaaattcg
    29161 tcgcttttta acgattcctt aatacaatat ttcataatct tagcaaggtc tgccgccgtc
    29221 gtgtgatgaa acccggcatc atccttcgca tccagtccgt tcggtgtaat aaagtagctg
    29281 tcctcacagc cgagttcctc tgccttcgca ttcatcagcg cggcaaatcc ctgcacatcc
    29341 cccgccgcaa attccgcgat ggccaccgca cagtcattgt aggattccag catcaggcca
    29401 tataaaagat ccctcagata aaactgttgt ccctcgtgca tccccagatg taccttcggc
    29461 tgtgacgctg cattttttga caccgtaacc acgctcgccg gatcacagtt ttccagtgcc
    29521 acgatacagg ttagaatctt tgtcgtactc gcattcgcca tcgcttcatg cccgtttttc
    29581 tcatagagaa ttcttccgga atccgcatcc atcaaaacgg cagattttgc gtacagttcc
    29641 gactctgccg gcacatcctg cgcccggaca cgcacaggcg aaaaaataag taagctcata
    29701 cttaacaata gagaaagaaa gcgtcgatac atgccattct cccaaaatga cttcactgat
    29761 gtatatgcgt ccctcatttt ttgcagaaca gaaacggcac gcaataagga actgccgtaa
    29821 taagcatatc gcgctttgat aagtaatatt attagaaaca cacttgggga tttcatgtgg
    29881 aaatgcagat ggaatattcg ttggagaaaa atgtgagcat t
//
