LOCUS       c00020_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OPNONDBM_23.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 04:25:36
            Original ID  :: gnl|Prokka|OPNONDBM_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 44063
            Orig. end    :: 67312
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[54063:57312]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1456..2913
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_42"
                     /sec_met_domain="FGGY_C (E-value: 6.1e-38, bitscore: 122.6,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 4.2e-80, bitscore: 260.8,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYSLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARSLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(3024..3959)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg20_43"
                     /sec_met_domain="LysR_substrate (E-value: 2.3e-33,
                     bitscore: 107.4, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.4e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFEHYTYQKEQ
                     LLLAVPKNYSVNTRLQKYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4075..5499
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_44"
                     /sec_met_domain="Lyase_1 (E-value: 1.5e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 5.6e-22, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5632..7317)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_45"
                     /sec_met_domain="FTHFS (E-value: 2.8e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_46"
                     /sec_met_domain="OKR_DC_1_C (E-value: 1.6e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 3.6e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EKSFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_47"
                     /sec_met_domain="Spermine_synth (E-value: 2e-53, bitscore:
                     172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 3e-15, bitscore:
                     48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_48"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 2.5e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 2.1e-35,
                     bitscore: 113.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKIDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_49"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 7.6e-15,
                     bitscore: 47.1, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTGASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDVECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRVGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_50"
                     /sec_met_domain="PAD_porph (E-value: 3.6e-128, bitscore:
                     419.3, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGDFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTQED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14490..15368
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_51"
                     /sec_met_domain="CN_hydrolase (E-value: 1.2e-55, bitscore:
                     180.7, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGVYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15596..16057
                     /locus_tag="ctg20_52"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIVLLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             16259..20968
                     /locus_tag="ctg20_53"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGESNCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDTGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVSNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEILVSQTKQDVKAVNVVITDELPSCLQLLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGTQSMEVLGVQQQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGEAETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEMVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEAYVKAKAEPTATPTPSVTPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYANSGGYSGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             20965..21852
                     /locus_tag="ctg20_54"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSKS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             22044..23135
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_55"
                     /sec_met_domain="Peripla_BP_3 (E-value: 3.5e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCKKIL"
ORIGIN
        1 gatgtaaaca aagcagagtg taatgcgctg gttgttttcc ttggaaactt cggacctgaa
       61 actcctgaaa ctctgatcgc agagagattt gacggacctt gtatgtatgt agcagcagca
      121 gaaggtgacg gtgatatgat caacggcaga ggtgatgctt actgtggtat gcttaactgc
      181 tcctacaact taaaaatgcg tcatctgaaa gcatatattc cggaataccc tgttggaaca
      241 gcagatgata ttgcaaagat gatcgctgat ttcgtaccgg ttgcacgtgc agtcatcggt
      301 gtcagcaatc ttaagatcat tactttcgga ccacgtccac aggacttctt cgcatgcaac
      361 gcacctatta aaggcctcta tgagctgggt gttgagattg aagagaactc agagcttgat
      421 cttcttgttt ctttcaaaga gcatgaaaat gatcctcgta tcccggaagt ttgtgcagat
      481 atggcaaaag agatgggcga aggcaaatat tatgctgacc ttaatgtgaa aatggcacag
      541 tttgagctta cacttcttga ctgggcagag gctcataagg gagcaagaaa atacgttgca
      601 tttgctgaca aatgctggcc tgcattcccg tcacagtttg gatttgaacc ttgctatgta
      661 aatagccgtc tggcttccag aggaattccg gtatcctgtg aggttgatat ctacggagca
      721 ctcagcgagt acatcggact ttgcatttcc aatgatgcag ttacactgct tgatatcaac
      781 aactctgttc cacagtatat ctatgatgaa gatattaaag gaaaatacga ttataagctt
      841 actgatacat ttatgggatt ccattgtgga aatactcctg catgcaagat gtgtgattcc
      901 agagctgtta aatatcagct gatccagcac agacttcttg agccggcagg atctgaacca
      961 gacttcacaa gaggaactct tgaaggtgat atcgctgcat ctgacattac attctatcgt
     1021 ttacagtgca attccgaggg cgagctggtt tcttatgttg cagaaggtga agtactggat
     1081 gtacctacaa gatcattcgg tggtatcggt attttcgcaa tcaaagaaat gggaagattc
     1141 taccgtcacg tactgatcga gggcaactat ccgcatcatg gagcagttat gtttggacat
     1201 tacggaaaag cattctatga ggtagtgaaa ttccttggac tggatgttaa gaagattgga
     1261 tacaaccagc cggcaggcgt aagatacccg acagaaaatc catggggtta atgaaaaatc
     1321 agtaaaacgg attattaatg ttcatgtgaa gtgaatgaat ctgaatacag aataaataaa
     1381 ctgacactat attaaaggca tcccggggct ttgctctggg atgtattaga ttagaaatag
     1441 aaaaggagag cacttatgta ttatattggt attgaccttg gtacttccgc tgtaaaactg
     1501 cttcttatgg aagaatcagg aaaaatctgt aacatcgtat ccagagaata ttctttattc
     1561 tttccacatc cgggctggtc tgagcagaaa ccggaggact ggtttgcgca gagtatggaa
     1621 ggcatgaaag agctgacaaa ggatatcgac agagcgcagg tagcaggaat tggttttggc
     1681 ggccagatgc atggtctggt aacacttgac aaggatgata atgtgatccg tcctgcaatc
     1741 ctctggaatg acggacgtac aggcgaagag acagaatatc tgaatacagt gatcggaaaa
     1801 gacaaacttt cacagtatac agcaaatatt gctttcgcag gcttcacagc accgaagatc
     1861 ctctggatgc agaaaaatga gcctgagaac tttaagaagg tagtaaagat tatgcttcct
     1921 aaggattatc tggcatatcg tctgtccggt tctttttgta cagatgtttc tgatgcttcc
     1981 ggtatgcttc ttcttgatgt gaagaaccgc tgctggtcaa aagaaatgct ggagatctgt
     2041 ggaatcacag aagagcagct tccgaaactg tatgagagtt gggaagtagt aggaactctg
     2101 aaacctgaga ttgcgaaaga acttggattc agtgagaatg taaaagttgt tgcaggtgca
     2161 ggtgacaatg cggcagctgc tgtaggaaca ggtacagttg gtgacggtca gtgtaatatt
     2221 tcccttggaa catccggaac tgtgtttatt tccagtaaaa actttggtgt ggacgaaaat
     2281 aacgcacttc attctttctg tcatgcagat ggaagctatc atctgatggg atgcatgctc
     2341 agcgcagctt cctgtaacaa atggtgggca gaggagattc ttcagacaaa ggatttcgca
     2401 gcagagcagg ctccaattca gaagctggga gagaatcatg tattcttcct tccatatttg
     2461 atgggagagc gctcacctca taataatcct gatgcaagag gtgtattctt cggaatgtcc
     2521 atggacagca caagagcaga catgacacag gctgttctgg aaggtgttgc ctttggtctt
     2581 cgtgattccc tggaagttgc aagaagcctt ggaatcaaga ttgagagaac caagatttgc
     2641 ggtggcggag ctaagagccc actgtggaag aagatcattg caaacgttat gaacctgaag
     2701 gttgatgttc tggagaacga agaaggaccg tccatgggtg gagctatgct ggcagcagta
     2761 ggctgtggtg cttacccgga tgtagaaacc atcggtaaga aatttgccaa agttgttgat
     2821 acagtagaac cggatcctga actggttgca aaatatgaag agagatatca gaagttcaga
     2881 actctgtatc cggcgatgaa gccattgttc taatcgaata tctgcctgac atactggggt
     2941 tgttgtgctt atttagcaca acaaccccat tttgacgtac atctgatgat gaccaatcac
     3001 catagcctat tgattatgac atatcaggaa aagggcagct tcaggaattc ttccatggct
     3061 ctgctgatat agcggccttt cttccagtaa aaaaacacag tgcgtttact actctgaccg
     3121 ggcagcttat aaaaaacaag ttctgaattt gttggaactc tggagagcag aagatccccg
     3181 atgaaagtga tacccattcc caaacatgca atattatagg cagtcatctg ctgatccagg
     3241 cgaaatacta cagaaggcga aaagtgattt tcctgacaaa tggtaagtgc acgcttaccg
     3301 gtatcattat ctgaacgaag aataataaat ggttcgttct cgaatttgtt taatggaaca
     3361 gaaggaatat gagaagaacg gaactgcccg ttccggattt cctcaatagg aatctgatat
     3421 ttctgcagtc tggtatttac tgaataattt ttgggaaccg ctagaagaag ttgttctttc
     3481 tggtaggtat aatgttcaaa aatctggtta tccaggatgc agttatcgat taccagatct
     3541 aactttccgg cctggagaaa ctgggatagc tttgctgtac tttcttctac aagagaaatt
     3601 tgaacatggg ggaatttttg ggaaaaatca gcaataaggg gaggcagaat ccacgaagaa
     3661 aaaaagttac tgccacctac attaagagtt cctgttttga gatttcccag atccagtagg
     3721 tagttttcga gattattttc aatatccatg actttttcaa cagcctgtat ataatgtttt
     3781 ccgacttcag ttaactgtaa aggtttggta cttcgatcaa aaataggata accaatgcgg
     3841 ttttccacac gttttacatt ggcgcttaaa gaaggctgcg aaatgaaaag agcagcagca
     3901 gctttggaaa agcttttttc cttgtagacc tcatagatgt attccattcc ctgaaacata
     3961 caaactcctc cgatatataa tttaaacact atatatttta taaaaatata tgtatttgat
     4021 tatattatag cagagatata taatgagggc aaatacatgg gagggcgaat aactatgaaa
     4081 aaaacagact atcgtgtaga aagggattct attggtgtaa aggatattcc ggaagatgta
     4141 tattatggag tacaatcctt acgtgcggct gaaaatttcc acattacggg gctgaatatg
     4201 catccggaaa ttattaacag tcttgcatac ataaaaaaag cagcagcgat aaccaattgt
     4261 gaggtggggc ttcttgagaa gaaaaaagca caggcgattg tccaggcatg tgatgaaatt
     4321 gtttcaggaa aattccataa tgaatttatt gtggatcctg ttcagggagg agctggcaca
     4381 tctttaaata tgaatgccaa tgaagtaatt gcaaatcgcg cgattgagat actgggagga
     4441 aaaaagggcg attatacaat tataaatcct aacgatgatg tgaattgtgg acagtctacc
     4501 aatgacgtta ttcctactgc cggtaaaatg acttctcttc gtttgttgca gaatctgaaa
     4561 aaacagcttc ttcgcctcta tgatgctctt aatgaaaaag ctacagagtt tgatcacata
     4621 ataaaaatgg ggcgtacaca gatgcaggat gcagtaccaa ttcgtctggg acaggaattt
     4681 aaggcatatt cggtagcaat catgcgtgat atccacagaa tggataaagc aatggatgaa
     4741 atgcggactc ttaatatggg aggtactgct attggaacag gaattaatgc agatgagggc
     4801 tatctgagaa gaattgttcc aaatctcact gaaatatcgg gaatggactt tatacaggct
     4861 tttgatctga ttgattccac tcagaatctg gatccatttg tagccgtttc cggtgctgtg
     4921 aaagcatgtg cggtaactct ttccaaaatg tcaaatgatc tccgcctgat gtcctctggt
     4981 cctcgtaccg gatttggaga aatcaatctt ccggcaaaac agaatggctc ctctataatg
     5041 ccgggtaaag tcaatccggt tattcctgaa gtagtgaatc aggtggcttt taatattatt
     5101 ggtaatgatg ttaccattac catggctgca gaggctggtc agctggaatt aaatgcattt
     5161 gagccgatta ttttctattg tatgttccag tctatcgata ctcttggcta tgcagtccag
     5221 acactggtag ataattgtat tgtaggaatt acagcaaatg aagaaaggtg ccgttatctg
     5281 gtagaaaaca gtgtaggtat tatcactgcg atcagccccc atcttgggta tcagaaggct
     5341 gcggatattg caaaaaaggc aattaagaca ggcgaatctg taagaagtct gattctgaaa
     5401 gaaaagctta tggacgagga tgaacttaat cgcattctgg atccgatcca tatgacggaa
     5461 cctggtattt ccggaaaaga ttatcttata aaaaaataaa gaaaaaaaca ggcgggaaaa
     5521 tcttcccgcc tgtaaaatcg tctggacata tatcatatat aaatatgatt tttatatttt
     5581 tgaattattc gattgaatac ggatgatttt atccgtttga tttcaactgg attagaacag
     5641 acctgtgatc ttacctgtct cgtctacgtc gattctctca gcagccggaa ctttaggaag
     5701 acctggcatt gtcatgatct cacctgtaag agctacgatg aatcctgcac cagcggaaat
     5761 cttcaggtta cgtactgtaa cttcgaagtc tgtaggagca cccagtttag tctggtcatc
     5821 tgttaagctg tactgtgtct tagctacaca aatcgggcag ttgccaaagc caagagcttc
     5881 taactgttta gcctgtttct gagcgttagc tgtcagaact actttcttac cgccatatac
     5941 tttctgaacg atctggttca gcttgtcttc gatagaacct tccagttcat atgcatagga
     6001 gaagtcgttt ggttcttcta caagacggat aacttcttct gcaagtttga ttccgccttc
     6061 gccgcctttt gcccatactt cagaaagagc aacgttaacg cccagttctt tacatttagc
     6121 ttctacaaag tcaagctctg cttttgtatc tgtagggaat gcgttgatag caacaacaca
     6181 tggaagtttg tatacgtttt tgatgttgga aacgtgtttt aacaggttcg ggataccttt
     6241 ttcaagagct tccaggtttt cattgttaag gtcagcttta gcaacgccgc cgttgtattt
     6301 cagggcacgt actgtagcta cgattacaac tgcgcttggt tttaaaccag ccatacggca
     6361 tttgatatca aggaatttct cagcaccaag gtcagcaccg aaaccagctt ctgtgattgc
     6421 ataatcagca agcttcatag ccatctttgt agctgttaca gagttacatc catgagcgat
     6481 gtttgcgaat ggtccaccat gtacgattgc aggaacgtgt tccagagtct gtacaaggtt
     6541 tggtttcaga gcatctttta acagggctgt catagcgcct tctgcgtgaa ggtcacctgc
     6601 tgttacaggt ttctgctcgg aaacttttcc gtatgtatat ccgatgatga tcttggataa
     6661 tctttctttc aggtctttga tgtcgcttgc aagacagaga actgccatga tttcagatgc
     6721 aactgtgatg tcgtatccgt cttcacgagg cataccgttt gtctttccgc caagaccatc
     6781 tactacgtta cgaagctgac ggtcgttcat atctacacat cttctccatg tgatcttacg
     6841 tgggtcgatg tttaatgcat tgccctggaa gatgtggttg tcgatcatgg ctgcaagtaa
     6901 gttgttagct gcgccgattg catggaagtc acctgtgaag tgaaggttga tgtcttccat
     6961 cggaacaacc tgtgcgtatc cgccgcctgc tgcaccacct tttacaccga ataccggtcc
     7021 taaggatggc tcacgaagag ctaccataac actcttgcca agtctctgca taccatctgc
     7081 aagacctaca gtagtagtag ttttaccttc tcctgctgga gttgggttga tagctgtaac
     7141 gaggattaat tttccatcct tcttatcact ttctttcaga agattgtagt cgatttttgc
     7201 tttgtatttt ccgtactgct ccagatattt gtcgtcaata cctgctttct ctgcgatctg
     7261 agtaattgga agcatctcgc attcctgtgc aatttcaatg tctgatttga atcccataat
     7321 tgtttttctc ctttcgtttc cgcataacat gaaaaacttc tgttgctgtt cactccgcga
     7381 tcagcaacaa ttattaattg aaagaagtat cggccggtct gtctgacatt cctgatttct
     7441 gctccggaaa ttataaaaaa aggccagtat ctgaatactt caaatactgc ccagacggtc
     7501 ggctcccaca aacctccgac tccacgtggt ttgcactcca ctctttccgt cagtactcga
     7561 aggttctttc aattgatgaa tacaatatat cattttgaga aaaaaatgtc aagaaatttt
     7621 tgttgaaacg tcaaaaaatg tgagtaaact ggataaaagt tgtgcaaatt gataagagaa
     7681 gagaatcgta atccctggta atgaaagaaa atacgttttc tcaagggaag aaattgttaa
     7741 aaaataaaca cagctttccc tgataaatga agaaaatata aaaagcgggt aaagctagag
     7801 cgtgtctgaa aaatcattcc cgcaatctgc acgccccact ttgcgggata tttcacccga
     7861 attcagttgc cgtagcccgc tacggcgccc tcatccgggc aaaatatccc acaaattgtg
     7921 acgcacatct tgcagaaagc ctttttcaga cacgctctag tgcaaaatat ggaaaatgga
     7981 attgacaaca gttcagaaga tatgttattc tcatctttag tatgaaaaga cactatcgtt
     8041 ttcatgcaaa tatttgctca cattcagaga cagtttctga atgttaagcc atacggacag
     8101 gcggggcagt tgccgggtgg gagacaccac attattgatt gagttaggag ctcaaatttt
     8161 ataagttgat tactttataa taatcagtgc gtaagcacac atcatcttgt gaaacggtca
     8221 ataagagcat agcatatatt tgccagcgat tgaagacgac agcagtcatg aatatttcag
     8281 aatacgggaa caggcacagg atacagacgg atttatacgg gaaatccggt cagtatataa
     8341 agagacagag cctgagaaat tctatagatc atgagagaag cagatggtga atgaacttat
     8401 ctgcttcttt ttttgtgcag atatagcaaa tatatataga aataattgaa tcattgtgcc
     8461 ggtttgaggc agtatacaat tgctgaatga tagaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccggagctt gcacagttgc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc acccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcgc atgcattcct tatggtagga ggaaccacat
     8821 ctgcagtgca gagcatgatc ctgtctgtct gcaaggcagg ggataagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg cggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgcg cagctgggca tttcccttgg catggaagtc agtcaggtgg
     9001 agaaggctat ggatgagaat ccggatgcgg tggcagttct tgtaaataac cctacctatt
     9061 atggaatttg ttcggatctg cggactatcg taaagaaggc tcatgcaaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtgtccg
     9181 gaatggcggc aggtgctgac atggcggcag tttctatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agcgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggccctcagg ggagagaaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gttattatgc atatggtatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc catttataca ctgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccatcgg agacaggctt caggatattg
     9661 agagactggt aggggcactg gctgatattg aacgtctgta taagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cagagaaaga atctctgccc atggaacagg cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctggaga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaaca tcttcaggtc ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtattct ctgataaaga tgaatttatt tatgatgaaa tggtcacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg atcatcggcg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtggaatc
    10321 cgataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggtggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaacagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaagatagat
    11041 gcggataatg cagcagaggt cgcagaattg atcagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggcgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctatgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgagaaatt taaggaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt atttagtgcc tatgccctga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaacggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct acgatttccc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa aaatattccg
    11641 ggagtacaga ggatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaatgg acaggaaatc
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatattgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttccg gctttgctct gtatcccatg attggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatagag gaactggatc ggatctgtga
    12421 ccatattatc tttaattcca cagcacagct gaagaaattt aaagaagtgt gtaccggagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg cgatctatga
    12541 tccctgtgcg ccgggttcca ggctgggggt taccagagag aactttgacg tggaatgtct
    12601 gaaatggatc gacggactgc attttcatac gctctgcgaa cagaatgcgg atgacctgga
    12661 gaaaacattg caggcggtag aggagaagtt tggagaattt ctgtctgagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatgagat
    12901 cagaacgctg attttggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgtctgg caggagatgt aatcggagat tattcctttg acagagagat
    13081 ccgggtcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaat ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcacaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agcttgggaa tgtttccggt gtgactttgc tggaatgcga gacagatgac gcctgggcca
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggagga gactttgatg gactttaccg gaactgggag aaggacgaca
    13681 gggtggctgc ctttatctgc aggactctcg gttgtccatg tctggatgcc agaccttttg
    13741 tgctggaggg cggttccatc cattctgacg gagaggggac tctgattgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtctct ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccag gaagatgtgg atggctttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggctgcca gttacgtgaa tttctatatt tccaatggag
    14221 ggatcatcct tccacaattt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gtcggcggtg
    14341 gaaatattca ctgtattacc cagcagattc ccggaaaaaa tatctgacct tgatgcagaa
    14401 aaactttgag agtcatgtgt ttgagggtta ttacctgaaa gttatgaaaa aacttactta
    14461 tgtaaacagg agcaggagga acagacagga tgagaaatgt aacagtggca gcagttcaga
    14521 tgaaatgcag taaaagtgtg gagaaaaata ttgcccatgc agaggaactg gtgcgtcagg
    14581 cagcagcaaa gggagctgag attgttcttc ttccggagct ttttgaacgg ccctatttct
    14641 gccaggagcg cagatatgag tattatgaat atgcgcagac tgcagaggaa aaccctgcag
    14701 tgcgtcattt cagcagggta gcggcagagc tggggattgt gatcccggtc agtttttatg
    14761 aaaaagaggt caataatacc tataacagcg ttgcggttct ggatgcagat gggaagaatc
    14821 tcggcgttta ccggaaaaca catattccgg atgaccatta ttatcaggaa aaattctatt
    14881 tcacaccggg agataccggc tttaaggttt ttgataccag atttggaacc attggagttg
    14941 gaatctgctg ggatcagtgg ttcccggaaa cggcaagatg tatggcactg cagggagcag
    15001 agcttctctt ttatcccact gccatcggca gtgaacccat cctggaatgt gacagcatgg
    15061 aacactggag aagatgtatg cagggacacg ctgcctccaa cctgatccct gtgatcgctg
    15121 ccaacagaat cggtgaggaa acagtggagc catgtccgga aaacggaatg cagaaatctg
    15181 ctcttaattt ttacggctct tcttttatca cagacaacac aggtgctctc tgtgcagaac
    15241 tgcccggagg ggaagagggg gtgcttgtaa gcacttttga cctggatgca ttaaaggcag
    15301 acagactgaa ctggggactt ttcagagacc gcagaccgga gatgtatgca aaaattgtcg
    15361 ggaaatgaca tacaagccaa aattccattg ccgcaggcaa tctggaatga attttggctc
    15421 agttactgag aacggagtga acagtaactg agtttataag aatttcataa aaagtttatg
    15481 attatattag ttgctacctg cggtatatat ggtaaaataa gagtacgaac gttactgata
    15541 acggagagag cagtagagtt ttgatatgta tttctggcaa aatggagtgt agaagatgaa
    15601 cagaaaagaa tttttggaaa tcctgagaag ccagcttgcc gggcagatgc aggaaggcaa
    15661 agcagcggca catatcaggt attatgaaga ttatatacag tctcaggtac gtggcggacg
    15721 ttcagagcag gaggtactgc aggaactggg agatccacat ctgatagcaa aaactctgat
    15781 cgatacagat gatggaagta cacaggaaga ttacggagag tattcttctt acggaagcag
    15841 ttatggcaat gagacagagc ttcctcatca gcaggagaaa agatggaaaa aagtaatcga
    15901 tctttctacc tggcatggca gggctgttgt tattgcagca gcggctgtta taattgtttt
    15961 actgatactg ataatcggag ttgcgattcc gttttttata attcttgcaa ttattcttta
    16021 ttttctttca tggctgaaga aaagaaatga tcaatgaaaa tctatgcagg gtttcagaaa
    16081 agaaaccctg cgcagaatct taaaatctta agtgtaaacg ttcttgtttc acgatattaa
    16141 ttccccttga atatttataa tcatacattt caacttattt ctattcttta atcctgcctg
    16201 gtgcagggaa aaatcccaca tttattttta tattttttgt tcggaaagga gacggaaaat
    16261 gaaacacaat ttcaaactga aagaacgcct tggagctttg ctgcttgcaa tgctttttat
    16321 tctgcaggca attctggggc ttgtgcctgt ctgcgtaact caggcggcac cgttaactgt
    16381 agaaacatgg gacagtgaca aggtggtaga ttatggttat cgctttaaca tgaagtttca
    16441 gcccggaatt accacatatg aatcttttgg gtgtgataat ctggacaggg aagctttttc
    16501 agacaatgga aaaagcgaac gtgacacaga gtgcgttcgt gtaggagcgg actataaagc
    16561 cggaagcgca gggatgcgtt ataacaatgt aggaaaagat ggaaatggaa atattgttga
    16621 tgtcagactc attcttgtgg gagtagagaa tgcagaaccc cgttatgatc tgcgcactgc
    16681 agaatcgatt gttcagaata aaggcggagc tacgtttgca tggaaagata atgaagctta
    16741 tccaatggtt ggcttttcca aaaacagtat cggtgtattt atttattctg taggatacgc
    16801 aaaggttaag tttcagtttc tgaagcatgg aacagaagaa acactgccga tcagtggcca
    16861 tggaaccata cgtgatattg atgcgggaca gggagtccgt attccgtcag acagcagtct
    16921 ggataatgca tatgttctga aaaacaatga ttatctgacg gtagatggaa attctgtaag
    16981 ctcacccctt ggttccgttg agccggatga tccgagagga tggctgaatc ttttttataa
    17041 tacagataat tttacggtag aattctgtca tcagttcaga ctggataaat gggataaaag
    17101 tcgtgaagat gccattgcaa aagccggttc tcaggaaaga tgggcagaga ttacaagaaa
    17161 taaatatctg gatccatcag gcaacagtta ttgtccgaac tttaaaggac agaaatactg
    17221 taaagcatat gcatattttg attttacatc ctattgtttc ggcgatgttg agatgaaaaa
    17281 agcacctgag aaacgtgtgg gagagtcaaa ctgtacatgg gaacaggcag ctgccgcatc
    17341 aaaagaaaaa ccttttggca ttcgtcaggg acaggaattt cagtatatga tccgggcaga
    17401 ggtgacaccc aatagactga aatcctttgt agtgcaggat atacttgagg attgtcttac
    17461 tatagaggat gcatcaaaag tcagtattgt gaatgataca gggcagacag tgacagactg
    17521 gtttgatgtt gctgttgaag gacagaaagt gacctgcagg gccaaagcag agagccttca
    17581 ggatgaagca tttacagata atcagactta cacatttact ttaaaagtac gccagagacc
    17641 ggaatcagaa attaacattt caaaatacct tgcagaggat ggatacagta ttcttgtatc
    17701 aaaccatgca tccatgagtt atgaacgtac aaacggaagc ggagatacaa tggatacgga
    17761 aacagtgtgg gtaaagggtg tgattccacc ggaactggaa gtaaagaaaa atacttctca
    17821 gtatgaatgg aaaacgggag atatcataga ttatgagatt ctggtttctc agacaaaaca
    17881 ggatgtaaaa gcagtaaatg ttgttattac agacgagctt ccatcatgtc tgcagcttct
    17941 ggaagggcag tatgctgtag agacaagtca gggaggtgag aactgtacgc ttaccggaca
    18001 gggagaaaat ggatggaaag cagagtgtcc gtccctgaag tatggggaga cgatcacaat
    18061 ccgttttaaa tgtcaggcat ctgcggattc caatggacag gaatgggaaa atattgtgac
    18121 tgcaacagcg gataatctga tcaatcctga gacaggagaa caggaatcca gaaaggatat
    18181 ggcagaagta tggccgaaca gtccacagct tgaaattgat aaaacagcag acaaatatga
    18241 atggcaggca ggagagcagg tagcttaccg gatcgtggtg aataatgtaa cggcaggaac
    18301 aattgcaaaa gatgtaacta ttactgatat tggtctgccg cagggactgg ttctggcagg
    18361 tggtacacag agcatggaag tactgggagt tcagcaacag gtaaactatc ccgtaccgga
    18421 taagaaaaca ggacaggcat atgaagcgag acctgtggat tctcagttga atgcagatga
    18481 gaacggattt tccttttatt gttcttatgt gccatacagt cagcctgtaa cgattatttt
    18541 ccattgtatc gcacaggaag aggcaaatgg acacgaaagc gtaaatgcag caactgtaaa
    18601 agctgctaat acagatgaga gatctgatga tgcagaagta tatgtaaatt caggagaatt
    18661 ctggattgag aaatctgcag atcattatga atggcaggtc ggagaacagg tacagtacaa
    18721 tgtggtggtg gagaataaaa aagcaggtac agtggcccgg aacgtaactg tctgggatac
    18781 cggtatgccg gcaggacttg cgctttcatc ggcagaggat gtatcggtaa gcggaatccc
    18841 gcagaatatt acgcagctga cagcagggac caaagatgtt ttgaaccagc tcaatccgga
    18901 attttataat gagacatcag agaaaccggt gaattatgaa tttcttcagg agggaagcgg
    18961 atggagactg aacatttcag atcttccggc aaatactccg gttatgattt ctttcctttg
    19021 cacagttacg gaagcggcaa atggaatgga aagcattaat gttgccaatg tgcaggcgca
    19081 gaatgcccct gtttcacagg atgacgcaga agtgtatgta aatacagcag ttctttctat
    19141 tgagaaaagt tttcagaatc catatctggc agccggggac ggacgtgcgg aaaatgaatt
    19201 tcgggtagga gaacaggtga attatcaggt tacggttaat aatcttcaga agggatctat
    19261 cgcaagaaat cttgtgatca gtgatctttc ccttcctgaa gggctggctc tggacggagc
    19321 tgaagatgct gttactgtaa gcggtgttcc ggctgttatt cagaatccgg tggcaggaac
    19381 tgatgatgca ggaaatcagc tgaatccgga aaattataaa gaaacagtgg aaaaaccggt
    19441 cagctgtcag gttacacgtc agggaaccgg atggatcgtg acgatttcag atcttccgta
    19501 tcagacacct gtgactgtta atttccgctg tactgcgcag gaaagcgtaa atgggatgga
    19561 gattgtaaat acagcacagg cgtatgcaga taatgcacag aaagtaaagg actcctcaaa
    19621 aatctgggtg aactcgcctg ttcttaaagt agagaagacg acggacaaac cattttacaa
    19681 atatggtgat attattacat atcgcattgt cctgacacag gagcagaccg gatgtgtggc
    19741 gcgtaatgtt actttgcagg atgtgatcga tactcaggga gtacgtcttc tgaaggattc
    19801 ggtgattctg atggatgaga aaggaaatgt ggcagatgct gatgtacaga tcaatgatga
    19861 taatactttc ctgatgtcaa caggcaggac actggtcagg gatagtagat atagtatctg
    19921 cgataatgat aaaggcggtc tttttgagca ggtaatgtat aatcctctgg actgtcagga
    19981 acagaaaagt atgatcgtgg aatatcaggc agcagtgatt gatgcagccc tggcaggaca
    20041 gaaagtgcac aatactgcag ttgcagacag cagtgaaaag atacctgcaa ccggggaagc
    20101 agagacagag gtacacagtc cgattctgga aattgtgaag gaatcagata agaaagagta
    20161 tgcgtccggt gaaaaaggat attataaact gacagtaaga caactgcgtg aggatgtcac
    20221 agatcagaat attgttatcg aagataaact ggaaacccaa ggggcttcca ttgtaaaaga
    20281 cagcattttt gtgaagaaaa acggtataga actgaaagat gccaaaatag aggcagatga
    20341 tacaggattt gtaattcaga caggagcatc gttgtcagat atggataaaa ttgaagtctg
    20401 ctatgaaatg gtatttaaaa cagaaagcac agagcctgaa aaaattgtaa acacagcgaa
    20461 agcaagaggt gatatttcac cggaaattac tgcacagcag gaggcatatg tgaaagcaaa
    20521 agcagaaccg actgccacac caacaccgtc tgtaacaccg aaaccaacag aaacaccaaa
    20581 gccgacagag acaccaaaac ctacagaagt accgaaaccg acagagcagc caaaagccac
    20641 accaacacca tctgtaccgg gaacctgccc gaaaatgact cctgtaccga cgaaagcacc
    20701 gttggcatct tacaatggtg gaaataatgg aggaacgact tccggaagcg gaggcagcag
    20761 ttacgcaaat tcgggtggat attccggtgg atacggaagc tatcagggtg gttccatggc
    20821 aggaagttct aaaacaggag atgtcagacc gtttaaaatg atggctgttc ttggacttat
    20881 cggaatggga ctgctgacag gaggtgtggt gatctacaga agaactgttt ccgggaaaag
    20941 aaatataaag ggtatgccgc ggaaatgaaa aaactcagaa catttgcagt aagtatgatc
    21001 atagcagcaa tcgggcttct tatatattgt gccggcttct atataaaaag ttatgaacag
    21061 aatcttgcag caaggcagga atatgcagag ctttcccaaa tggcaggggt gaagaacaga
    21121 gaaggtgccg gattattggc agatggcaaa aaaactgatg aagacagcag tacaaaaaac
    21181 agtgaaaaaa aacgcaggaa aaaacagaga agatcttctg aatcaaaaaa caaaaactgt
    21241 acagatgaaa tcagggaatc cttcgggatt tcctgggaaa atttaagaaa gatcaactct
    21301 cagacagttg cctggattac tgtcccggga gccgatattt cttatcctgt agttcaggcg
    21361 gcagatgatg aatattacct gaaacataat ttcagaggag aggaagatct gtttggatgt
    21421 atttttctgg aacatgacat aaaaaagaat tttacagatt cccacagtat tctttacggg
    21481 cataatatag aaggtaatat gatgtttgca aatctgaacc gttatgaaca gcctgaattt
    21541 ctgaaaaaat gtcctgaaat tgagatcaca acaccaaaaa gaaagtttct gtacaaaatt
    21601 ttttctgtgg aacaggcatc ttccaaaagc ccggcatttg aatatggata caagttatcc
    21661 agtcctgcat acaggagaca attatctata ttgaaaaata attccatgta tgacacagga
    21721 gtagagcctg atgaaaggga gagaatggtg actctgatca cctgtaattc acgtctggat
    21781 aaagaaatac gtatggcggt acatgggatt tgccatgaat gttatggtat agaaaaagct
    21841 gagccgaagt gatgttgaaa tcaatcggat attggtaact ttcgtaaagg atgaactgtt
    21901 actgttcaca tatcactatc cctcgaggtg ttttggaaaa aactaatgaa aaatctctcg
    21961 atattttgta taatttatgc ataaaaaaca acttgttcgt acgtgcgtac aagttgtatc
    22021 ctaaatacag gagggaagaa gacatgacag ataatggaaa gccgaaatat ttctcactga
    22081 tggaacagct cagaagtgat attatgtcag gagctatccg accgggagag aagcttcctt
    22141 cagaaaacga gctttcacag aaatattccc tgagcagaca tacagttcgt aaagcactgg
    22201 gaatcctgga gcaggacgga tatgtagagg catttcacgg aagaggtact tattgctctg
    22261 agaatatgcg ccatataaag aattcaaaga atattgcggt agtgaccaca tatatttctg
    22321 attatatttt tccgagactg atacagggaa tggataatgt cctttcagaa agcggttaca
    22381 gtattatcct gaaaaacaca gcaaacagca gacagaaaga ggccagatgt ctggaggaac
    22441 ttctgaagaa agatattgat ggactgatca ttgaaccaag caaaagtgag atgatctgta
    22501 aacacagaaa tctttatcag aatctggata aatttgaaat tccgtatgtg tttattcagg
    22561 gaatctattc agaaatgagg gataaacctc atattcttat ggatgatgca cagggaggct
    22621 atcttgtaac aaaatatctg ctggaactgg gacataaaaa gatcaagggt ttctttaagg
    22681 cagacgatat gcagggactg gagcgccaca agggatatgt gaaggcctta caggagtcag
    22741 ggattgccta tgatcctgat gatgttgtct ggtttcatac agaggacagg aaagtaaaac
    22801 ctgcactgat ggcaaaagaa atggtacaga gcggacagct tccggatgga atcgtctgtt
    22861 acaatgatca gattgctgtt caggttatgg aagaactgga gaaaatggga gtcaggatac
    22921 cggatgatat ttccattacc ggttatgaca attcactgta tgctcagcga ggaagcggaa
    22981 tcacaacgat agctcatccg caggaaaagc tgggagaaat ggcagcagag cttatacttg
    23041 agaagatcaa cggagttcct gaagaagaaa gtaaggttga aagactgatt tatccggaac
    23101 tgatcatacg gggatcatgc aaaaaaatat tgtaaacaaa tgaaataaat aaaaaataaa
    23161 tccaggagga attttatcat gaaaacagga agaaactata agttctggtt ttgtacaggt
    23221 tcacaggatc tttacggaga tgagtgctt
//
