LOCUS       c00064_gnlPro..        14384 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OPNONDBM_67.
ACCESSION   c00064_gnlPro..
VERSION     c00064_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 04:25:36
            Original ID  :: gnl|Prokka|OPNONDBM_67
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14384
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14384
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8992:11244]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8993..11244
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14384
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14384
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             3..182
                     /locus_tag="ctg64_1"
                     /transl_table=11
                     /translation="NLEAVENFKGSRDEKLVVLYCKQLGINYKNLSDEEFRWLIRILKK
                     SKKMGTPISQRKKR"
     CDS             complement(278..928)
                     /locus_tag="ctg64_2"
                     /transl_table=11
                     /translation="MKEKSKSEVSIIGGADGPTSIFIAGRTRKKPLKVRIRNIIYRYRR
                     KIVEKKVVADSHTLDELVQYAMNTYNLIETNSTERKYIEQQKNLKESLILQHKPEVLGE
                     MKDIPKPDVSNEESVREYFCKIKTRSEMIAEMPDNVIPMNFHLYEIRIGDDSLEMEIDY
                     IWNIFGISYSGNKKVMKQFEKISKDLYIYYGVSEDDIKKKTERYLSLVTALSS"
     CDS             complement(976..1593)
                     /locus_tag="ctg64_3"
                     /transl_table=11
                     /translation="MNGKHLFLTSAGLTDKMKEKFFDIIGKCPKDVKVLYIPTAGIETD
                     GARESLAICFHELFLMGIQYENILVYNLELILSKDYQRTYSSYVTTPFMLTRLLTFEEL
                     NQFDAVFVSGGDVSVLCREMSRTGFDRILNNAIKNGLIYVGISAGSMYAAGNLTDGLHI
                     IDNPIIPHWNGSETTVLPNGKEEIKLADGKAVYVEDNYMSVI"
     CDS             complement(1704..3002)
                     /locus_tag="ctg64_4"
                     /transl_table=11
                     /translation="METKLERIAEISANSPGPEFTSLYHLINKEMLLQCHKELDGNKAV
                     GVDEITKKEYGRNLEQNLDDLVERLKRKSYKPQPSIRVYIPKSNGKLRPLGIACYEDKI
                     VQLALKKILEAIYEPRFLNCMYGFRPNRGCHNAIKELCKRLNNTKICYIVDTDIKGFFD
                     HMKHEWIIKFLKLYIKDPNIIGLVKKYLKVGVLDNGELMANEEGSAQGNIISPILANIY
                     MHNVLTLWYKFIITKECKGDNFLIVYADDFVAGFQYKWEAENYYKLLKERMEKFGLQLE
                     DSKSRLLQSGAYIARAKQKSGECIRLQTFDFLGFTFYCGRSRKGMPYIMPKTSSKKFRQ
                     KIRDIKVWLYANRDQPLKKLMGMLNLKLIGHYRYYGISFNGRMISNYKQQVRELLFKVL
                     NRRSDRKSYTREGFIEMLKYYPLAMPKIYVSLF"
     CDS             complement(3518..3901)
                     /locus_tag="ctg64_5"
                     /transl_table=11
                     /translation="MSGLKKHIYEEKNGLHYTLNGDYYLPDLKLPEEHRPIGKYGRMHR
                     EYLREVHPARLNTLTLTGELWTYLADLNEQAQKRLDTIIEQMKAAEGVTEELKSICQME
                     WVQRCNNIHNRAEEIVLHEMIYS"
     CDS             complement(4268..4933)
                     /locus_tag="ctg64_6"
                     /transl_table=11
                     /translation="MEVVVNDSVTREAISRAEERKFLRFVKEDPHFCRYYEGIYILFKT
                     GLRISEFCGLTISDIDFKEHTINIDHQLQKKSKIGYYIQETKTTSGTRKIPMTADVEEC
                     FRKIIEKRNPPKAEPMVDGKSGFLYFDKNESICYSLHWEHYFQHIIQKYNNTYKVQMPV
                     ITPHVCRHTYCSNMAKSGMNPKALQYLMGHSDISVTLNTYTHVNLEDAREEVARIQVV"
     CDS             complement(5028..5462)
                     /locus_tag="ctg64_7"
                     /transl_table=11
                     /translation="MSEKRRDHRGRILHNGEIQLSDGRYRFKYVDEMGKERCVYSWRLD
                     HNDATPKGKRRTLSLREMEKKIEADHFEQIATNGGNMTVLELVEKYTSTKTGVRPTTVA
                     GYGTVINLLKKDPFGKRRIDTVRISDAKCWLIHLQQVEKL"
     CDS             complement(5598..5807)
                     /locus_tag="ctg64_8"
                     /transl_table=11
                     /translation="MNHTEKTIPVWEKYSLNVSEAAEYYRIGEKRLRQIAGENEGADFI
                     LEVGSHIRFKRKLFEDYLDTASTV"
     CDS             complement(5804..6619)
                     /locus_tag="ctg64_9"
                     /transl_table=11
                     /translation="MREEDTVCVGSDGLKYCKVCGEAKEAFFPKGGFMGMKKHSRQCAC
                     DRKVYEEEQKYFKDKEHRELVSRNTSICFDESRMEEWTFENADMSDTVMHRAKKYVDNW
                     EEMKRNHIGCLFWGPVGTGKSFIAGCIANELLKQEVMVKMTNFNTIIDDIFPLADKTEY
                     INALASYQLLIIDDLGVERNSEYALGIIFSVIDRRIRSGRPLIITTNLPLKEIKNETML
                     DKRRIYDRILEMCTPMYVGGTSKREVIASMKMEKAKTLLNTNRGEEDCE"
     CDS             complement(6619..7146)
                     /locus_tag="ctg64_10"
                     /transl_table=11
                     /translation="MKYEYMKESEQMLQYFQFPKFLLKLRISQTAKFLYMILYDRARIS
                     RKNSWIDKYGNVYLIFPIDELSVQIDKCKSSVKTALKELDDVGLLVRRSGGFSKPNHLY
                     VKIPSDEIGLQPVDNKAVEKIVATEPEKPPSSGRKNGCGGVGNVAPSKVTEKYKSNKYH
                     EVNYCYGEGESL"
     CDS             complement(7193..7585)
                     /locus_tag="ctg64_11"
                     /transl_table=11
                     /translation="VYYSIVILTILYYLRVADLMGITSPYPRENIIAGNYILADTQAFL
                     SKCHRQQNKEILIRHSPRIGECFLLSNIQLTEKIKKISSGGCKNASQRFVLMKGYLGGK
                     NKKLSSRACIYALHLLNICKDIFEPT"
     CDS             complement(7819..8232)
                     /locus_tag="ctg64_12"
                     /transl_table=11
                     /translation="MNKKKVAFICVHNSCRSQIAEALGKHLASDVFESYSAGTETKLQI
                     NQDAVRIMKELYGIDMEAEGQYSKLIDEIPVPDIAISMGCNVGCPFIERPFDDNWGLED
                     PTGKSDEEFKKVIDEIRMQIFILKQRLDEFEEN"
     CDS             complement(8225..8968)
                     /locus_tag="ctg64_13"
                     /transl_table=11
                     /translation="MYEENQKLKTWITPDLATEYLAGAVLLGAAPCTAMVFVWSTLTKG
                     NPAYTVVQVASNDIIILFAFVPIVKFLLGVSNVSVPFQTLFMSVVLFVVIPLAAGIITR
                     LLVVRKKGTEYFEQTFLHKFDSATTVGLLLTLILIFMFQGEVVLDNPLHIILIAVPLII
                     QTFFIFFLAFGVCRIIRLPYDIAAPAGMIGASNFFELAVAVAVALFGTSSPAALATTVG
                     VLTEVPVMLTLVKIANKLKEKFKYE"
     CDS             complement(8993..9694)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 89.6; E-value: 4.3e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg64_14"
                     /sec_met_domain="Fer2_3 (E-value: 1.3e-28, bitscore: 89.6,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00075, bitscore: 10.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVYKIRIRRQESQKSDSYWQEFEFDGSKNSSVANVLKELNSRTPL
                     KDNSGNIVTPISWECSCMVRKCGACAMLINECPRLACSTFLHTLKGSTITLEPLSKFPL
                     VRDLIVDRSILFENLKKLNLWLESEAYMNPWTHEPRYQSARCLMCGCCLEVCPNFSANG
                     TFAGAVAAVNAFRILNEEQESTHLNEISAEYKKKYFEGCGKSLSCHDICPIGLPVEELL
                     VRSNAAAVWGK"
     CDS             complement(9700..11244)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 269.9; E-value:
                     1.4e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg64_15"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.1e-83, bitscore:
                     269.9, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.9e-17,
                     bitscore: 52.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTIIIIGAGLAGLSAALQAAENGCNVKLVSSLPSERAQSVMAE
                     GGINAALNTKDENDSPEEHFTDTIKAACGLADPNAVWGMTQAAPELVHWLLKLGVKFNM
                     SGYDDVDLRNFGGQKKKRTAFAQSDTGKQIMTAMIDAVRRKEAFGMVERFSHHSFLTLR
                     LCGNICCGCVIRDEYSQETVELPGDAVIVATGGMHGLFGNTTGSLSNTGEVTAELFRLG
                     VPLANGEMIQYHPTTVKCGGKRMLISEAARGEGGRLFAMKDGKQWYFMEEKYPELGNLM
                     PRDITAREIWKVSHESEVFLDMTEISEEIISNKLSGLADDCMTYLHKDIRKEPVSVLPG
                     IHYFMGGILVDEQHRTPIQNLYAAGECCAQYHGANRLGGNSLLGALYGGRVAAKSACEQ
                     ADVVDLSCATQIDFPPASQISEIKQLNKVMQETMGVVRNENTLLNGIQTVQALTGNLPL
                     LGMAVLKSALARKESRGAHWREDYPKSNDDDYLKTTVARFDGKQIQISFVPVPERR"
     CDS             complement(11241..11780)
                     /locus_tag="ctg64_16"
                     /transl_table=11
                     /translation="MRKWNTILSVLMLLIFMIHGIMGSFMLNGVGSSAGKLLAWIGVGI
                     LVVHTVIGVILTVQSLQTAKQSGKMYLKQNAIFWARRASGLAILILLFFHIGLFGKVQN
                     GTYILFPFTTVKMVTQLLFVAAIFVHIFINIRPLLVSLGIISYKERRGDIYLILSVLLL
                     FIAGAVIFYYIGWQYL"
     CDS             complement(11791..12309)
                     /locus_tag="ctg64_17"
                     /transl_table=11
                     /translation="VKRKLILLVVTIVFLVGFGVILHSPPSMIDAVTGATPKSKKAAQA
                     SAQLEGSYVLGINMMSDGLDNENTRNKLKELALDDSETNETDLMKTDISFRLYVSETDY
                     PLASYAKKLCDRLKQAGFFVDLKEYSNTMMLSRVVSGKYDVFLASDDFIDVTTLSQMDY
                     MIMDSEEMR"
     CDS             complement(12326..14383)
                     /locus_tag="ctg64_18"
                     /transl_table=11
                     /translation="VGELDGVQSSVVNLMKQTLTINVAQTAADTIASQIETIVHSHEPD
                     VEVSEIVQESYIPEKKQEANESYNNEDKKLTVRLATGAAIYAIGMALTVFAKVPLPIEL
                     AFLIVSYVILGGDVVWQAVRNISKGRVFDEHFLMSVSTIGAFVIGEYPEAVAVMLFYQV
                     GEFFQSLAVKRSRKSISDLMDIRPDSATVRRNGELITISPENVSIGEIIIVKPGEKIPL
                     DGVVLDGDSMLDTRALTGESVPRSVHKGDEALSGCMNQTGVLMIKTTKAFGESTASKII
                     DLVENASSRKAPTENFITTFARYYTPVVVILAAFLAILPPIILGGGWTEWIRRGFVFLV
                     VSCPCALVISIPLTFFGGIGAASKRGVLVKGSNYLEALNNVSVIVFDKTGTLTKGVFNV
                     TDILPANGFSKEQVLEYAAEAESFSNHPIAKSILAAYGKEMDQSVIFDYKEISGYGISV
                     MAGEKKVFAGNTKLMDTECIEYTTCEKAGTKVYLAVDGQYAGCILITDEVKPDSKKAIS
                     DLKHIGVEKTVMLTGDDEKIGKAVAEELQLDEYYAQLFPDQKVEKFELLDSKKRQGSKL
                     AFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKLVDAIDVAKATKQI
                     VMQNIVIALGIKSVFLILGALGIAGMWEAVFGDVGVTIIAVLNAMRILKK"
ORIGIN
        1 aaaatctgga agcggtcgaa aatttcaagg gcagccggga tgaaaagctc gttgtacttt
       61 actgcaagca gctcggtatc aactataaaa atctgtcaga cgaagaattt cgctggctga
      121 ttcggattct caaaaaatca aagaaaatgg gaacgcctat cagccagagg aaaaaacggt
      181 aacaaaaaac cgctgttgca tggttgtgtt agcttccatg tagcagcggt ttatgctgtg
      241 gttattcagt tgaaatttca gaaagacagg ctggaattta tgaacttaat gccgttacca
      301 atgataaata tctttctgtc tttttcttaa tatcatcttc actaacacca taatagatat
      361 acaaatcttt tgaaattttc tcaaactgtt tcattacttt cttgtttcca gaataagata
      421 taccgaatat attccaaata taatctatct ccatctcaag agaatcatca ccgattctta
      481 tttcatatag atgaaagttc ataggaatta cattatctgg catttcggca atcatttcgc
      541 ttcgagtctt tattttacaa aaatattctc tgacagattc ttcattagaa acatccggct
      601 ttggaatatc cttcatttca cctaaaactt ctggtttatg ctgtaaaatc aaactctcct
      661 ttaggttttt ttgttgttca atatattttc tctcagttga attagtttca attagattgt
      721 aggtattcat tgcatattgt accaattcat caagagtatg tgaatctgca accactttct
      781 tctctactat cttacgtcta tatctgtaga taatatttcg tatccttact tttagaggct
      841 ttttccgtgt tctgccagct ataaaaatac ttgttgggcc atctgcacca cctattattg
      901 aaacttcact tttgcttttt tctttcataa gtgttcatcc tcgcaaattg gaatttgact
      961 aatcctacat gtgcatcata ttacactcat gtaattatcc tctacataaa cagcttttcc
     1021 atcagcaagc ttaatctctt ctttgccgtt cggtaatact gttgtttcag aaccattcca
     1081 atgggggata ataggattgt caataatatg taatccatct gttaaatttc ccgccgcata
     1141 catacttcct gcactgattc cgacatatat aagtccgttt ttaattgcat tattaagtat
     1201 tctatcaaaa ccagttctag acatttcacg acaaagcaca gatacatcac caccactgac
     1261 aaaaacagca tcaaattggt ttaattcttc aaaagttaat agccttgtaa gcataaacgg
     1321 ggttgtaaca tacgaagaat aggttctttg atagtctttt gaaagaatta attccagatt
     1381 gtacactaat atattttcgt actgaattcc cattagaaag agttcatgaa aacatattgc
     1441 aagcgactct cttgcaccat ctgtttcaat gccagctgtt ggaatataaa gcactttcac
     1501 atccttcgga cactttccaa taatatcaaa gaatttctct ttcatcttat cggtcaaccc
     1561 tgcagatgta agaaatagat gttttccatt catattcttt tacctcgtca gtcgagtaga
     1621 cttacacctc acaatgtaag cccctcacag aaccgtacgt gcggctttcc cgcatacggc
     1681 tcttcataat aatatttaca gtctcaaaac aagctgacat aaatctttgg cattgccaat
     1741 ggataatatt tcagcatttc aatgaatcct tctcttgtat aactctttct gtcacttcgt
     1801 ctattcagca ccttaaacag aagttctctc acttgttgtt tgtagtttga aatcattctg
     1861 ccattaaaac ttatgccata gtacctataa tggcctatta gtttcagatt tagcataccc
     1921 attagtttct ttagcggttg gtctctattc gcatataacc ataccttgat gtctcgaatt
     1981 ttctgtctga atttcttaga gcttgtcttt ggcattatat atggcatgcc tttgcgtgaa
     2041 cgcccacaat agaatgtgaa tcccagaaaa tcaaatgttt gtaatctgat acactcaccg
     2101 ctcttttgct ttgcccttgc aatataagca ccgctttgta agagacgact tttactgtct
     2161 tctaattgca aaccgaactt ttccattcgt tctttaagaa gcttgtagta attctctgct
     2221 tcccatttat attgaaatcc tgcaacaaaa tcatctgcat atacaattag aaagttatct
     2281 cccttgcatt ctttggtaat aataaactta taccatagtg tcaatacatt gtgcatatat
     2341 atgtttgcta ggattggact tatgatattg ccttgagctg aaccttcttc attcgccata
     2401 agttcaccat tatccagcac tcccacttta agatacttct tgacaagacc aattatgttg
     2461 gggtctttaa tataaagttt gagaaacttg ataatccatt catgcttcat atggtcgaag
     2521 aatcctttga tgtcagtatc cacaatatag cagattttcg tgttgtttaa tctcttacac
     2581 agttctttta ttgcgttatg acatcctcga tttggtctga atccgtacat gcagttcaga
     2641 aatctcggtt catagatagc ttccaatatc ttctttaatg ctaattggac tattttgtcc
     2701 tcatagcatg caattcctaa tggtcgaagt tttccattgc ttttagggat atatacccta
     2761 attgatggct gtggtttgta tgattttctt ttcagtcttt ctaccaagtc atctaagttt
     2821 tgctccagat ttctcccgta ctctttctta gtaatctcat caacaccgac tgctttgttt
     2881 ccgtctaatt ctttgtgaca ttgcaaaagc atttctttat tgattagatg atacaacgat
     2941 gtgaactctg gtcccggcga atttgccgat atttctgcta ttctttctaa tttcgtttcc
     3001 atcaatacct ccgtccctga gtacggttga tgtgtcctca gaaagaccat tattatgtag
     3061 ctccctttcc tccgttggca ttacccaact tcttcagtac tatgaagcta tccgactgcc
     3121 tactgttctt ttgacattct cctgttttgc agttgtttgc catacttgca atggcaagaa
     3181 acaataggct ctccccagtt gactgaataa tcacaatgta aaacataaag tgctctttga
     3241 ccccgcagaa gcaaaccatt tctcaccaat gcgaattgat ttgtattgct ttccgtcgaa
     3301 attagaacgt cagccttcta aatgtcaaaa tttcgaggct caatcacact ctctattttc
     3361 tcgctgtcta cgcttagcaa ctaccattac tgacagtcac ccaagactcg ctactggcgg
     3421 ttggttaggc cttaccagac aggcattcca cctgctagac tactcgccct tatctgggcg
     3481 cacaactccg atttatcata atcattctac cataccgtta tgaataaatc atctcatgca
     3541 aaacaatttc ttctgcccga ttgtgaatgt tattgcaacg ctgcacccat tccatctgac
     3601 agatactctt taattcttct gtgaccccct cagcagcttt catctgctct atgattgtat
     3661 ctaatcgctt ctgtgcctgt tcgttcagat ctgcaagata tgtccataat tcccctgtca
     3721 gggtcaatgt attcaatctg gctgggtgga cttctcttaa atattcccgg tgcatccgtc
     3781 cgtactttcc gatagggcgg tgttcctccg gcaatttcaa atctggtaaa taataatctc
     3841 cattcagagt gtaatgcagt ccgtttttct cttcataaat gtgtttcttt aatccgctca
     3901 tatttttaat ctcctcattc tggtttgttg tttctgcaag tctgactctc cagaaatatt
     3961 ggtaaatcat tggtaaaatc gagaattgaa cacaagaaat gctatttata gaagtattta
     4021 agacgattta agactttttc tcacgaacag taaatcctgc cgtggcagat aaatagtact
     4081 tttatcattg ttgcataacc tcgcatttct tagtttttct tggtttttcg ggctttgtaa
     4141 gcctttgtaa atttttgctt tctggcataa cctggtttat tttcgcataa tatcgtcagc
     4201 aaaaggtgta aaataaggtg tatgtttttc cattttacac cttgctattt tcaattaaaa
     4261 atcgtaatta cacaacctga atccgggcaa cttcttccct ggcatcctca agatttacat
     4321 gcgtatatgt attcagcgtt acgctgatgt ctgagtggcc catcaaatat tgcaatgctt
     4381 ttggattcat tccggatttt gccatatttg agcaataggt gtgccgacat acatgcggtg
     4441 taatgacagg catctgtact ttataagtat tattatactt ctgaatgatg tgttgaaaat
     4501 aatgctccca atgcagggaa taacagatac tttcattttt atcaaagtat aagaatccac
     4561 tttttccatc taccataggt tctgctttgg gcgggtttcg tttttctatt attttccgaa
     4621 agcattcctc tacatccgca gtcataggta tctttctcgt tccactggtt gttttagtct
     4681 cttgaatata atatccgatt tttgatttct tctgcaattg atgatcaatg ttgattgtat
     4741 gctccttgaa atcaatatca gaaatcgtta aaccacaaaa ttccgaaatg cgaagacctg
     4801 ttttaaacaa tatgtagatt ccctcataat acctgcaaaa atgaggatcc tccttcacaa
     4861 atcgtagaaa ctttcgttcc tcagccctgc tgattgcctc tcttgtcaca ctgtcattca
     4921 caaccacttc cattagctga aactgaaatg aatttttcct gatcaggtca tcatccactg
     4981 ccaactggaa tgccggacga agaactcctc ggattgaatg gatggaacta taacttttct
     5041 acctgctgaa gatgtatcag ccaacatttt gcatccgaaa tccgaaccgt atcaatcctt
     5101 ctttttccaa atggatcttt cttcaataaa ttgataactg ttccgtatcc tgcaactgta
     5161 gtaggtctga caccggtttt tgttgatgta tatttttcaa ccagttccag taccgtcata
     5221 tttccgccat ttgttgcaat ctgctcaaaa tggtccgcct cgattttctt ctccatctcc
     5281 cgaagcgaca aagtacggcg ctttcctttc ggagttgcat cgttatggtc taagcgccag
     5341 ctatatacgc agcgctcctt tcccatctca tcgacatact taaatcgata tctgccatca
     5401 gataactgta tttctccatt gtgtaatata cgtcctctat gatctctcct tttttcactc
     5461 ataatatttt agtctccttc atcaaatgtt catttaactt ggaagaccgt ctcggtttat
     5521 tcattatacc acaagacctt tccttcgcta agataaaatg aacattattt tcattactat
     5581 ttcttctatt ctgtcactta aactgtgctg gctgtatcca gataatcttc aaacaatttc
     5641 cttttgaatc gaatatgaga acctacttcc aaaatgaaat ccgctccctc attttcacct
     5701 gcgatttgtc tcaatctctt ttctccaatt ctgtaatatt ctgctgcttc ggatacattt
     5761 aaagaatatt tctcccaaac aggtattgtt ttttctgtat gattcattcg cagtcctcct
     5821 cccctctgtt tgtattcaac aacgttttcg ctttctccat tttcatactt gcaatcactt
     5881 ctctcttact tgtgcctcca acatacatag gcgtacacat ttctaaaata cggtcataga
     5941 tacgtctttt atctaacatg gtctcatttt ttatttcttt cagcggaaga ttggtcgtaa
     6001 tgatcaaagg tcgtcctgaa cggattcttc gatctatgac gctaaaaata attcctaacg
     6061 catattctga atttcgttcc actccaagat catcaataat caaaagctga taagacgcca
     6121 atgcattgat atattccgtt ttgtctgcca gtggaaatat atcatcaata atggtattga
     6181 aatttgtcat ctttaccatt acttcttgct taagaagttc attggcaatg caccccgcaa
     6241 taaaactttt cccggtacca accggtcccc agaacaaaca gcctatatga tttcttttca
     6301 tttcctccca gttatcaaca tatttttttg ctctatgcat taccgtatct gacatatctg
     6361 cattctcaaa tgtccactct tccattctgc tctcgtcaaa acagatactt gtatttctgc
     6421 tgactaattc ccggtgctct ttgtctttaa aatatttttg ttcttcttca tatacttttc
     6481 tgtcacaggc acattgcctg gaatgtttct tcattcccat aaatccaccc ttggggaaaa
     6541 atgcttcttt cgcttcccca cagactttgc agtatttcaa gccatcactg cctacacata
     6601 cagtatcttc ttctctcatc acaaactctc tccttcccca tagcaataat ttacttcatg
     6661 atatttatta cttttatatt tctcagttac tttactaggt gccacatttc cgactcctcc
     6721 acagccattt ttacgaccag atgaaggtgg cttttccggc tctgttgcaa ctatcttttc
     6781 aaccgcctta ttgtcaaccg gctgtaaacc tatctcatca gatggaattt tcacatataa
     6841 atgattgggt tttgaaaatc caccggatct gcgaaccaat agtcccacat catctaattc
     6901 cttcaacgct gtttttacag aagatttgca tttatcgatt tgaacagaca attcatctat
     6961 tggaaatatc agataaacat ttccatactt gtctatccag ctattctttc tcgatatccg
     7021 tgcccggtca tacaaaatca tataaaggaa ttttgcagtt tgagaaattc gcagctttaa
     7081 taaaaacttc ggaaactgga agtactgaag catctgctct gactccttca tgtattcata
     7141 tttcattctt ttctcgcctc atttctgttt ctaattattg taaaaatcat ttttatgtcg
     7201 gctcaaaaat gtccttacat atattcaaaa gatgaagggc ataaatacag gctcttgagg
     7261 aaagtttttt atttttcccg cccaaatacc ctttcattaa tacgaaacgc tgagaggcat
     7321 ttttacagcc ccctgatgaa atttttttaa ttttttcggt taattgaata tttgaaagca
     7381 aaaaacactc acctattcta ggtgaatgcc ttatcaaaat ttccttattt tgttgtctgt
     7441 gacacttact cagaaacgct tgcgtatctg ctaaaatgta attgcctgca attatatttt
     7501 cacgtgggta tggggacgta atccccatca agtctgctac tcgtaagtaa tacaaaattg
     7561 tcaaaatgac aatactgtaa tacacgggtg gatcttgctc tggatgtaac atatgaattc
     7621 atgcaataat aggcccaaat gggcactttc gccatttgag cctatatatt gtatgtcttt
     7681 tggatgcccc tttgaaatag cctctgctgg cataaaagaa ggcagacagt cttgttataa
     7741 aaccacctgc cttgttgatt attcttatat gtttttttgt atctcatccg ttcgacaaac
     7801 tgcaatttct caacttcttt agttttcttc aaattcatcc aatcgttgtt tcaatataaa
     7861 aatttgcatc cttatctcat caataacctt cttaaactct tcgtcactct ttccggttgg
     7921 atcttcaagt ccccaattat catcaaacgg tctttcgata aacggacatc ccacattaca
     7981 acccattgaa attgcaatat ccggtactgg tatctcatca atcagcttac tatattgtcc
     8041 ttctgcttcc atatcaattc catacaattc tttcataatc cggactgcat cctgattaat
     8101 ctgtagtttt gtttctgtcc ctgccgaata actttcaaat acatccgaag ccagatgttt
     8161 tcccaaagct tctgcaatct ggcttctgca tgaattatga acgcatataa aagcaacttt
     8221 tttcttattc atacttgaac ttctccttta atttgtttgc aatcttcaca agagtaagca
     8281 ttaccgggac ttctgttaat acacctactg tagttgccag tgccgctgga cttgatgtac
     8341 caaataaagc tacagcgact gcaacagcta actcaaagaa attcgatgca ccaatcattc
     8401 cagccggggc tgcaatatca tacggaagtc tgataattct gcatactcca aatgccagaa
     8461 agaatataaa gaatgtctga atgatcagcg gaactgcaat caatataatg tgcagtggat
     8521 tgtccagcac cacctcgccc tgaaacataa aaatcagtat cagcgtgagc aaaagtccca
     8581 ctgttgttgc ggaatcaaat ttatgcagaa aagtctgctc aaagtattcc gtacctttct
     8641 ttctgactac cagcagcctt gttatgattc cggctgcaag tggtattact acaaatagaa
     8701 ccacactcat aaataacgtc tgaaacggaa cactaacatt agaaacacca agcagaaatt
     8761 tcacaatcgg tacaaatgca aataatataa taatgtcatt tgatgccacc tgaactactg
     8821 tataagccgg atttcccttt gtcagcgtac tccagacaaa taccatagcg gtacatggag
     8881 ctgctccgag aagcacggct cctgcgagat actccgtcgc aagatccggt gtgatccatg
     8941 tcttaagttt ttgattctct tcatacattc attatagctt ttatcatcca ttttatttgc
     9001 cccaaacagc cgctgcattc gaccttacaa gcagttcttc cacaggcaga ccaatcggac
     9061 aaatatcatg acaagataac gacttcccgc atccctcaaa atatttcttc ttatattcag
     9121 cagaaatctc attcaaatga gtgctttcct gttcttcatt cagaatccga aatgcgttga
     9181 ctgcagcaac agcgcctgcg aaagtcccat ttgcagagaa gttgggacac acttcaaggc
     9241 agcagccaca catcagacag cgtgccgact ggtatctcgg ttcatgtgtc cacggattca
     9301 tataagcttc actttcaagc caaaggttca gttttttcaa attttcaaac agaattgacc
     9361 ggtcaacgat caaatctctt acaagcggaa atttgcttaa aggttccaag gtgattgtag
     9421 aaccttttaa cgtatgtaga aatgtagagc atgccagcct cggacattcg ttaatcagca
     9481 tggcgcaagc cccacatttt cgcaccatac agctacattc ccagctgatg ggagtaacta
     9541 tattccctga attatctttc aaaggggttc tactgttcaa ttcctttaga acattggcaa
     9601 cagagctgtt tttgcttccg tcaaactcaa attcctgcca ataactgtct gatttctgac
     9661 tctcctgccg cctgattctt attttatata ccaagtgaat caccgccttt ctggaacagg
     9721 tacaaaggaa atctgtatct gctttccatc aaatctggct accgttgttt taaggtaatc
     9781 atcgtcattg ctcttcggat aatcctcccg ccagtgtgca ccacggcttt cttttcttgc
     9841 aagagcactc tttagaactg ccatgccaag caatggaaga tttcctgtca gcgcttgtac
     9901 cgtttgaatc ccatttaaca acgtattctc atttctgaca acgcccatag tctcctgcat
     9961 cactttgttt aattgcttta tttctgaaat ttgagacgct ggtggaaaat ctatctgtgt
    10021 cgcacaagat agatctacta catctgcctg ttcgcatgct gattttgccg caacacgtcc
    10081 tccgtataac gctcctaaca gagaatttcc accaagacgg ttggcaccat gatattgggc
    10141 acagcattct ccggcagcgt aaagattctg aatcggcgtt ctgtgctgct catccaccag
    10201 aatacctccc ataaaatagt gaattcccgg taaaacagac accggttcct ttcgtatatc
    10261 tttatgcaaa taggtcatac aatcgtctgc cagaccagat agcttatttg aaataatctc
    10321 ctccgatatt tccgtcatgt caagaaatac ctctgattca tggctgacct tccatatctc
    10381 tctggcggta atatctcgtg gcatcagatt tccaagctcc gggtattttt cctccatgaa
    10441 ataccattgt tttccatctt tcatggcaaa caacctgcca ccttcccctc tggccgcctc
    10501 gctgatgagc atgcgttttc caccacattt cacagttgtc ggatgatact ggatcatctc
    10561 gccatttgcc agaggaacac caagccggaa caattctgcg gtgacttctc ctgtattgct
    10621 cagcgaaccc gttgtatttc caaacaatcc gtgcatacca ccggtggcaa caataaccgc
    10681 atcccccggt aattccacag tctcctgact gtattcatcc ctgattacgc agccacaaca
    10741 aatattgcca cacagacgaa gtgttaggaa agaatgatgg ctgaaccgtt ctaccatacc
    10801 aaatgcttct ttcctgcgaa cagcgtctat catagctgtc atgatctgct tcccggtatc
    10861 gctctgtgca aaagcagtcc gtttcttttt ctgcccgcca aaatttcgca gatccacatc
    10921 atcatagcca ctcatgttaa atttaactcc aagttttagc agccagtgca ccagctccgg
    10981 tgctgcctgt gtcattcccc aaactgcatt tggatctgcc agaccacatg ctgcctttat
    11041 tgtatctgta aaatgttctt cgggactgtc gttttcatct tttgtattca aagctgcgtt
    11101 gataccgccc tccgccataa cagactgtgc ccgctctgac ggaagggagg aaaccagttt
    11161 tacattgcat ccattttccg ctgcctgcaa agccgctgaa agtcctgcca gtccagcacc
    11221 tataataata attgtcttac tcatagatat tgccacccaa tataatagaa aataactgcg
    11281 cccgctataa acagaaggag caccgaaaga atcaaataaa tatcacccct tcgttcttta
    11341 taactgatga ttcccagcga tacgagcaat gggcggatat tgataaaaat atgaacaaag
    11401 attgccgcca cgaacaaaag ctgagttacc atctttaccg ttgtaaaagg gaacaaaata
    11461 tatgtcccat tctgcacctt tccaaacaag ccaatatgga agaacagcag gatcagtatt
    11521 gccagcccac tggctcgtct cgcccagaat atggcgttct gtttcagata catttttccg
    11581 gattgcttcg ctgtctgtaa actctgaact gtcaggatga caccaatcac cgtatgcaca
    11641 acaagaatac caacaccaat ccatgcaaga agtttccctg cactacttcc aactccgttc
    11701 agcataaagc ttcccatgat tccatgaatc ataaaaatga gaagcattaa aacagacaaa
    11761 atcgtattcc attttctcat aaattcccgc tcacctcatt tcttcgctgt ccatgatcat
    11821 atagtccatc tgtgataacg ttgtaacgtc aataaaatca tccgatgcca ggaatacatc
    11881 atactttcca cttaccactc ttgatagcat cattgtgtta ctgtactctt tcagatctac
    11941 gaaaaaaccg gcctgtttca acctgtcaca gagtttctta gcataactgg caagcggata
    12001 atccgtctca gatacatata accgaaaact aatgtccgtt ttcatgagat ctgtttcatt
    12061 tgtttccgaa tcgtccagtg ccaattcttt taatttattc cgggtgttct cgttgtcgag
    12121 accatctgac atcatattaa taccgagaac ataagagcct tccaactgtg cggaggcttg
    12181 agccgccttt tttgacttcg gtgttgctcc tgtgactgca tcaatcatag aaggcggtga
    12241 atgtaatatg acaccaaaac ctacaagaaa aacaatcgta acaactaaca gaatcagttt
    12301 tcgtttcaca ttcccacctc atttcctatt ttttcaaaat tctcattgcg ttcaaaacag
    12361 caattatggt aacgcctaca tcaccaaata cagcttccca cattcccgca ataccaagag
    12421 cgccaagaat caggaacaca ctcttaattc caagggcaat cactatattc tgcatgacaa
    12481 tttgctttgt cgcttttgcc acatcaatcg catccaccag cttagatggt tcatctgtca
    12541 tcagaaccac atccgcagct tcaatggccg catctgaacc aagaccaccc attgcaatac
    12601 caacatccgc acgagcaagg acaggagcgt cattgatacc atcaccaaca aaagctaatt
    12661 tgcttccctg tctcttttta ctgtctaaaa gctcaaactt ttccactttt tgatcaggaa
    12721 acagttgtgc ataatattca tccaactgca attcttccgc aacagccttt ccgatttttt
    12781 catcatcacc agtaagcatg actgtttttt ccacaccgat atgtttcaaa tcagaaattg
    12841 cttttttact gtccggcttc acttcatctg ttatcaaaat acatcctgca tattgaccat
    12901 ctacagccaa ataaactttt gtacctgctt tttcacaggt tgtgtactct atacattctg
    12961 tatccataag tttcgtattg ccagcaaaaa ctttcttttc ccctgccatt acactgattc
    13021 catatcctga aatttcctta taatcaaaaa tcactgactg atccatttct tttccataag
    13081 cagcaagaat ggattttgca ataggatggt tagaaaaact ctctgcctct gccgcatact
    13141 ccagaacctg ttcttttgaa aatccatttg caggcaaaat atccgtcaca ttgaaaacac
    13201 cttttgtaag tgttccggtt ttatcgaaca caataacgct gacattatta agtgcctcta
    13261 aataattgct tccttttaca agaacacctc gtttagatgc tgcaccaatg ccgccgaaga
    13321 aagtcagcgg gattgaaata accaatgcac atggacaaga taccacaagg aaaacaaatc
    13381 ctctgcgaat ccactctgtc cagcctccgc caagaatgat cggtggcaga atcgccagaa
    13441 aagctgctaa gattacaacc acaggtgtat aataacgtgc aaatgtagta ataaaatttt
    13501 ctgttggtgc ttttcggctt gacgcatttt ccacaagatc aataatcttt gaagccgtag
    13561 attcaccaaa tgcttttgtt gtcttaatca ttaagacacc cgtctgattc atacaaccgg
    13621 aaagtgcttc gtctccttta tgaacacttc tcggaactga ttctcctgtt aaggcccttg
    13681 tatccagcat agaatctcca tccaatacca caccgtctaa tggaattttt tcaccaggct
    13741 ttacaataat aatctcacca atggagacat tttctggaga tatggtaatc aattccccat
    13801 ttcttcttac tgtagcagaa tctggacgta tatccattaa gtctgatata gattttctgg
    13861 aacgcttaac agccaatgac tgaaaaaatt cacctacctg atagaataac ataacagcaa
    13921 ctgcttctgg atattcacca atgacaaaag ccccaatcgt agaaacactc atcaaaaaat
    13981 gttcatcaaa tacacgcccc tttgaaatgt tcctcacagc ctgccataca acatctccac
    14041 caagaataac ataagaaaca atgagaaaag ctaactcgat aggcagtggc actttcgcaa
    14101 aaacagtcaa tgccatacca atggcataga ttgctgcacc agtcgctaaa cgaactgtca
    14161 acttcttatc ctcattgtta taggattcat tggcctcctg ctttttttcc ggtatataag
    14221 attcctgtac aatttcagaa acttccacat ctggctcatg gctatgaaca atcgtttcaa
    14281 tctgactggc tatcgtatct gcggctgtct gagcaacatt gattgtaagc gtctgcttca
    14341 tcagatttac cactgaggat tgcactccat ccaactctcc gact
//
